Compounds > acetylcysteine

acetylcysteine and Granulocytic Leukemia, Chronic

acetylcysteine has been researched along with Granulocytic Leukemia, Chronic in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (44.44)	29.6817
2010's	5 (55.56)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chen, X; Huang, L; Ke, F; Tian, J; Wu, L; Xu, J; Zhang, N; Zheng, M	1
Bagchi, J; Bandyopadhyay, S; Bhattacharjee, S; Biswas, N; Chaudhuri, U; Ganguly, D; Ghosh, M; Mandal, L; Paul, K; Rakshit, S	1
Altman, JK; Dolniak, B; Glaser, H; Goussetis, DJ; Kroczynska, B; McNeer, JL; Platanias, LC; Sassano, A	1
Meshkini, A; Yazdanparast, R	1
Chodaparambil, JV; Felsher, DW; Huang, M; Kusler, B; Mitchell, BS; Pollyea, DA; Whang, P; Xu, L	1
McKallip, RJ; Sun, J	1
Adjei, AA; Bone, N; Bruzek, LM; Chandra, J; Hackbarth, J; Karp, JE; Kaufmann, SH; Kay, NE; Le, S; Loegering, D; Narayanan, VL; Sausville, EA; Tefferi, A	1
AbdulKarim, B; Bourhis, J; Deutsch, E; Dugray, A; Eschwege, F; M'Kacher, R; Maggiorella, L; Marangoni, E; Rasy, SD; Turhan, AG; Vaganay, S; Vainchenker, W	1
Grune, T; Ullrich, O	1

Other Studies

9 other study(ies) available for acetylcysteine and Granulocytic Leukemia, Chronic

Article	Year
A novel synthetic novobiocin analog, FM-Nov17, induces DNA damage in CML cells through generation of reactive oxygen species. Pharmacological reports : PR, 2016, Volume: 68, Issue:2 Topics: Acetylcysteine; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Damage; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Mitochondria; Novobiocin; Reactive Oxygen Species	2016
N-acetyl cysteine enhances imatinib-induced apoptosis of Bcr-Abl+ cells by endothelial nitric oxide synthase-mediated production of nitric oxide. Apoptosis : an international journal on programmed cell death, 2009, Volume: 14, Issue:3 Topics: Acetylcysteine; Annexin A5; Apoptosis; Benzamides; Cell Line, Tumor; Cell Survival; Free Radical Scavengers; Fusion Proteins, bcr-abl; Hematologic Neoplasms; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Nitric Oxide; Nitric Oxide Synthase Type III; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Reactive Oxygen Species; Up-Regulation	2009
Arsenic trioxide-dependent activation of thousand-and-one amino acid kinase 2 and transforming growth factor-beta-activated kinase 1. Molecular pharmacology, 2010, Volume: 77, Issue:5 Topics: Acetylcysteine; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Dithiothreitol; Enzyme Activation; Genetic Variation; Hematopoietic Stem Cells; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; MAP Kinase Kinase Kinases; Oxides; Phosphorylation; Protein Kinases; Reactive Oxygen Species; RNA, Small Interfering; Tretinoin; U937 Cells	2010
Involvement of oxidative stress in taxol-induced apoptosis in chronic myelogenous leukemia K562 cells. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:4 Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Drug Antagonism; Drug Screening Assays, Antitumor; Flow Cytometry; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Reactive Oxygen Species; Superoxides	2012
Reactive oxygen species regulate nucleostemin oligomerization and protein degradation. The Journal of biological chemistry, 2011, Apr-01, Volume: 286, Issue:13 Topics: Acetylcysteine; Animals; Blast Crisis; Carrier Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Cysteine Proteinase Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Leukemic; GTP-Binding Proteins; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leupeptins; Lymphoma; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Neoplasms, Experimental; Nuclear Proteins; Oxidants; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Multimerization; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins	2011
Plumbagin treatment leads to apoptosis in human K562 leukemia cells through increased ROS and elevated TRAIL receptor expression. Leukemia research, 2011, Volume: 35, Issue:10 Topics: Acetylcysteine; Apoptosis; Blotting, Western; Catalase; Cell Survival; Flow Cytometry; Gene Expression; Humans; In Situ Nick-End Labeling; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Naphthoquinones; Oxidation-Reduction; Oxidative Stress; Polyethylene Glycols; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction	2011
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells. Blood, 2003, Dec-15, Volume: 102, Issue:13 Topics: Acetylcysteine; Adamantane; Antioxidants; Apoptosis; Buthionine Sulfoximine; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Glutathione; Humans; Hydroquinones; K562 Cells; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Quinones; Reactive Oxygen Species; Tumor Stem Cell Assay; Tyrphostins	2003
BCR-ABL down-regulates the DNA repair protein DNA-PKcs. Blood, 2001, Apr-01, Volume: 97, Issue:7 Topics: Acetylcysteine; Animals; Apoptosis; Blast Crisis; Child; Cysteine Endopeptidases; DNA Repair; DNA-Activated Protein Kinase; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Induction; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Multienzyme Complexes; Neuroblastoma; Nuclear Proteins; Oligopeptides; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrphostins	2001
Proteasomal degradation of oxidatively damaged endogenous histones in K562 human leukemic cells. Free radical biology & medicine, 2001, Oct-01, Volume: 31, Issue:7 Topics: Acetylcysteine; Benzamides; Cell Nucleus; Cysteine Endopeptidases; Enzyme Inhibitors; Histones; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Multienzyme Complexes; Oxidation-Reduction; Oxidative Stress; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex	2001