acetylcysteine and Glioma

acetylcysteine has been researched along with Glioma in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (17.07)18.2507
2000's17 (41.46)29.6817
2010's17 (41.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shukla, A; Trivedi, SP1
Luo, Y; Pengfei, G; Wang, H; Zhang, J; Zhang, S; Zhong, J1
Ahmed, AU; Auffinger, B; Kim, CK; Lesniak, MS; Moon, KS; Tobias, AL; Ulasov, IV1
Kayama, T; Kitanaka, C; Narita, Y; Okada, M; Sato, A; Seino, S; Shibui, S; Shibuya, K; Watanabe, E1
Congdon, KL; Sampson, JH1
Hu, L; Jiang, ZC; Li, HX; Li, LL; Lin, ZG; Yang, KB; Zhao, SG1
de Andrade-Lima, LC; Garcia, CC; Martins, DJ; Menck, CF; Quinet, A; Rocha, CR; Vessoni, AT; Vieira, DB1
Chi, G; Ge, P; Lu, B; Luo, T; Luo, Y; Ma, H; Wang, C; Zheng, L; Zhou, Z; Zhu, D1
Moir, RD; Myre, MA; Tanzi, RE; Tesco, G; Wasco, W; Washicosky, K1
Dixit, D; Ghosh, S; Koul, N; Mishra, PK; Sen, E; Sharma, V1
Chen, S; Ding, J; Ma, J; Sheng, C; Tan, Y; Wang, H; Wang, Z1
Ahn, YS; Jung, SE; Kim, YK; Ko, JH; Lee, JH; Lim, MH; Youn, DY1
Hamada, K; Kawase, T; Ohta, S; Takahashi, S; Toda, M; Yamada-Okabe, H; Yoshida, K1
Berger, F; Bouamrani, A; Dimitriadou, V; Jourdes, P; Pernod, G; Simard, B1
Chen, YC; Cheng, MC; Chien, CC; Huang, GC; Lin, CT; Shen, SC; Wu, J; Yang, LY1
Chen, ZQ; Fu, SB; Huang, Z; Li, JH; Liu, JY; Ren, FB; Yue, W; Zhan, Q1
Andreazza, AC; Braganhol, E; de Souza, DO; Gonçalves, CA; Nardin, P; Quincozes-Santos, A; Tortorelli, L; Tramontina, AC; Wartchow, KM1
Chen, CH; Lin, ML; Ong, PL; Yang, JT1
Chen, PY; Chiou, SM; Chiu, CH; Chung, JG; Huang, HY; Kuo, CL; Yang, JS; Yang, ST1
Brannon, J; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Lebedeva, IV; Linehan, WM; McKinstry, R; Mitchell, C; Qiao, L; Rosenberg, E; Sarkar, D; Su, ZS; Valerie, K; Yacoub, A1
Broaddus, WC; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Lebedeva, IV; Lister, A; McKinstry, R; Mitchell, C; Qiao, L; Ramakrishnan, V; Sarkar, D; Sigmon, C; Su, ZZ; Yacoub, A1
Eugster, HP; Frei, K; Ishihara, H; Könü, D; Kubota, H; Möhler, H; Rodak, R; Yonekawa, Y1
Bravo-Gómez, ME; Cruz, A; Gracia-Mora, I; Luvia, ST; Marquez-Rosado, L; Moreno-García, ME; Osorio-Rico, L; Palencia, G; Rodríguez-Enriquez, S; Rodríguez-Ropon, A; Ruiz-Ramírez, L; Sánchez, A; Sotelo, J; Trejo-Solís, C; Zúñiga, S1
Kim, MS; Kim, SJ; Lee, CH; Lee, JW; Lee, SH; Park, MJ; Shin, SH; Yoo, H1
Giles, GI; Gillespie, GY; Griguer, CE; Kelley, EE; Lancaster, JR; Oliva, CR1
Brem, H; DiMeco, F; Fiorindi, A; Gaini, SM; Legnani, FG; Olivi, A; Pradilla, G; Recinos, PF; Thai, QA; Tyler, BM1
Robbins, ME; Smith, PS; Spitz, DR; Zhao, W1
Antolín, I; García-Santos, G; Herrera, F; Martín, V; Rodriguez, C; Rodriguez-Blanco, J1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
García-Escudero, V; Gargini, R; Izquierdo, M1
Han, D; Kobayashi, MS; Packer, L; Roy, S; Sen, CK; Tritschler, HJ1
Higuchi, Y; Matsukawa, S1
Hirota, N; Iida, M; Kuribayashi, N; Matsumoto, K; Sakagami, H; Sunaga, S; Takeda, M1
Khan, M; Pahan, K; Singh, AK; Singh, I1
Blaivas, M; Kish, P; Muraszko, KM; Ross, DA; Strawderman, M1
Eitel, K; Hermisson, M; Wagenknecht, B; Weller, M1
Mertz, K; Morgan, JI; Schmidt, J1
Feinstein, DL; Gavrilyuk, V; Horvath, P; Selmaj, K; Sharp, A; Stasiolek, M1
Groscurth, P; Hermisson, M; Krammer, PH; Liston, P; Wagenknecht, B; Weller, M1
Iwama, T; Naganawa, T; Nakashima, S; Noda, S; Sakai, N; Sawada, M; Yoshimura, S1
Ikemoto, H; Kitagawa, H; Matsumoto, T; Tani, E1

Other Studies

41 other study(ies) available for acetylcysteine and Glioma

ArticleYear
An in vitro analysis of the rat C6 glioma cells to elucidate the linear alkylbenzene sulfonate induced oxidative stress and consequent G2/M phase cell cycle arrest and cellular apoptosis.
    Chemosphere, 2018, Volume: 205

    Topics: Acetylcysteine; Alkanesulfonic Acids; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Glioma; Humans; M Phase Cell Cycle Checkpoints; Oxidative Stress; Rats; Reactive Oxygen Species

2018
The proteasome inhibitor lactacystin exerts its therapeutic effects on glioma via apoptosis: an in vitro and in vivo study.
    The Journal of international medical research, 2013, Volume: 41, Issue:1

    Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Glioma; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Proteasome Inhibitors; Rats; RNA, Messenger; Tumor Burden; Xenograft Model Antitumor Assays

2013
N-acetylcysteine amide augments the therapeutic effect of neural stem cell-based antiglioma oncolytic virotherapy.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2013, Volume: 21, Issue:11

    Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Glioma; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Neural Stem Cells; Oncolytic Virotherapy; Oncolytic Viruses; Virus Replication; Xenograft Model Antitumor Assays

2013
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells.
    Stem cell research, 2014, Volume: 12, Issue:1

    Topics: Acetylcysteine; Animals; Brain Neoplasms; Buthionine Sulfoximine; Cell Differentiation; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glioma; Humans; Hydrogen Peroxide; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 7; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; RNA Interference; Transplantation, Heterologous

2014
Enhanced oncolytic virotherapy through oxidative stress inhibition.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2013, Volume: 21, Issue:11

    Topics: Acetylcysteine; Adenoviridae; Animals; Glioma; Neural Stem Cells; Oncolytic Virotherapy

2013
Blockage of potassium channel inhibits proliferation of glioma cells via increasing reactive oxygen species.
    Oncology research, 2014, Volume: 22, Issue:1

    Topics: Acetylcysteine; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation, Neoplastic; Glioma; Humans; Potassium Channel Blockers; Potassium Channels; Reactive Oxygen Species; Tetraethylammonium; Tumor Suppressor Protein p53; Up-Regulation

2014
Chloroquine-induced glioma cells death is associated with mitochondrial membrane potential loss, but not oxidative stress.
    Free radical biology & medicine, 2016, Volume: 90

    Topics: Acetylcysteine; Cell Death; Cell Line, Tumor; Chloroquine; Glioma; Humans; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species

2016
JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production.
    Molecular neurobiology, 2017, Volume: 54, Issue:5

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Enzyme Activation; Glioma; Humans; Hydrogen Peroxide; Intracellular Space; JNK Mitogen-Activated Protein Kinases; Mitochondria; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Reactive Oxygen Species; RNA, Small Interfering; Superoxides

2017
Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
    Cellular signalling, 2009, Volume: 21, Issue:4

    Topics: Acetylcysteine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzazepines; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclin D1; Fibroblasts; Glioma; Hexanones; Humans; Hydrocarbons, Chlorinated; Indoles; Leupeptins; Mice; Peptide Fragments; Proteasome Inhibitors; Purines; Recombinant Fusion Proteins; Roscovitine; Threonine

2009
Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation.
    Free radical biology & medicine, 2009, Aug-15, Volume: 47, Issue:4

    Topics: Acetylcysteine; Apoptosis; Caspase 3; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Farnesyltranstransferase; Gene Expression Regulation; Glioblastoma; Glioma; Humans; Oxidative Stress; Phosphorylation; Poly(ADP-ribose) Polymerases; Polyenes; Polyunsaturated Alkamides; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; RNA, Small Interfering; STAT3 Transcription Factor; Superoxide Dismutase; Superoxide Dismutase-1; Telomerase; Thioredoxins

2009
Amyloid-beta1-42 induces reactive oxygen species-mediated autophagic cell death in U87 and SH-SY5Y cells.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 21, Issue:2

    Topics: Acetylcysteine; Adenine; Amyloid beta-Peptides; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Division; Cell Line, Tumor; Drug Interactions; Glioma; Humans; Membrane Proteins; Mice; Mice, Mutant Strains; Neuroblastoma; Neurons; Oligopeptides; Peptide Fragments; Reactive Oxygen Species; RNA, Small Interfering

2010
Down-modulation of Bis sensitizes cell death in C6 glioma cells induced by oxygen-glucose deprivation.
    Brain research, 2010, Aug-19, Volume: 1349

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; Catalase; Cell Death; Cell Line, Tumor; Down-Regulation; Electrophoretic Mobility Shift Assay; Free Radical Scavengers; Glioma; Glucose; Hypoxia; L-Lactate Dehydrogenase; NF-kappa B; Rats; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Superoxide Dismutase

2010
Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells.
    Journal of neuro-oncology, 2011, Volume: 103, Issue:2

    Topics: Acetylcysteine; Blotting, Western; Cell Line, Tumor; Cell Movement; Cytoskeleton; Down-Regulation; Fluorescent Antibody Technique; Gene Expression; Gene Expression Profiling; Glioma; Humans; Mannose-Binding Lectins; Membrane Glycoproteins; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Receptors, Cell Surface

2011
Induction of the fibrinolytic system by cartilage extract mediates its antiangiogenic effect in mouse glioma.
    Microvascular research, 2011, Volume: 82, Issue:1

    Topics: Acetylcysteine; Aminocaproic Acid; Angiogenesis Inhibitors; Angiostatins; Animals; Blood Vessels; Caudate Nucleus; Cell Line, Tumor; Fibrinolysin; Fibrinolysis; Glioma; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Neovascularization, Pathologic; Plasminogen; Plasminogen Activator Inhibitor 1; Rats; Survival Analysis; Tissue Extracts; Tissue Plasminogen Activator; Transfection; Xenograft Model Antitumor Assays

2011
Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells.
    Chemico-biological interactions, 2011, Aug-15, Volume: 193, Issue:1

    Topics: Acetylcysteine; Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Chromatin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioma; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Vitamin K 3

2011
Calcium overload induces C6 rat glioma cell apoptosis in sonodynamic therapy.
    International journal of radiation biology, 2011, Volume: 87, Issue:10

    Topics: Acetylcysteine; Animals; Apoptosis; Calcium; Caspase 3; Cytochromes c; Egtazic Acid; Fluorometry; Glioma; Hematoporphyrins; Immunoblotting; Intracellular Membranes; Necrosis; Photosensitizing Agents; Rats; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tumor Cells, Cultured; Ultrasonic Therapy

2011
High-glucose and S100B stimulate glutamate uptake in C6 glioma cells.
    Neurochemical research, 2012, Volume: 37, Issue:7

    Topics: Acetylcysteine; Brain Neoplasms; Cell Line, Tumor; Cell Lineage; Culture Media; DNA Damage; Glioma; Glucose; Guanidines; Humans; Nerve Growth Factors; S100 Calcium Binding Protein beta Subunit; S100 Proteins

2012
Novel multiple apoptotic mechanism of shikonin in human glioma cells.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Catalase; Cell Line, Tumor; Cyclosporine; G1 Phase Cell Cycle Checkpoints; Glioma; Glutathione; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidative Stress; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Toluene; Tumor Suppressor Protein p53

2012
Danthron triggers ROS and mitochondria-mediated apoptotic death in C6 rat glioma cells through caspase cascades, apoptosis-inducing factor and endonuclease G multiple signaling.
    Neurochemical research, 2012, Volume: 37, Issue:8

    Topics: Acetylcysteine; Animals; Anthraquinones; Apoptosis; Apoptosis Inducing Factor; Caspases; Cell Death; Cell Line, Tumor; Cytochromes c; Endodeoxyribonucleases; Glioma; Membrane Potential, Mitochondrial; Mitochondria; Rats; Reactive Oxygen Species; Signal Transduction

2012
MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:7

    Topics: Acetylcysteine; Adenoviridae; Adjuvants, Immunologic; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Brain Neoplasms; Carcinoma, Renal Cell; Caspases; Cell Division; Free Radical Scavengers; Free Radicals; Genes, Tumor Suppressor; Glioma; Glutathione Transferase; Humans; Interleukins; Kidney; Kidney Neoplasms; Oxides; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, Virus; Recombinant Fusion Proteins; Tumor Cells, Cultured

2003
Melanoma differentiation-associated 7 (interleukin 24) inhibits growth and enhances radiosensitivity of glioma cells in vitro and in vivo.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-15, Volume: 9, Issue:9

    Topics: Acetylcysteine; Adenoviridae; Animals; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Brain Neoplasms; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Gene Transfer Techniques; Genes, Tumor Suppressor; Glioblastoma; Glioma; Glutathione Transferase; Humans; Interleukins; Necrosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tetrazolium Salts; Thiazoles; Time Factors

2003
Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.
    Journal of neurosurgery, 2005, Volume: 102, Issue:6

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase Inhibitors; Cell Line, Tumor; Collagen Type XI; Cysteine Proteinase Inhibitors; Fas Ligand Protein; Gene Expression; Glioma; Humans; Membrane Glycoproteins; Mitochondria; Phosphatidylserines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Taurine; Thiadiazines; Vascular Endothelial Growth Factor A

2005
Cas IIgly induces apoptosis in glioma C6 cells in vitro and in vivo through caspase-dependent and caspase-independent mechanisms.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:6

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Animals; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line, Tumor; Cell Proliferation; Chromatin; Copper; DNA Fragmentation; Dose-Response Relationship, Drug; Glioma; In Vitro Techniques; Lipid Peroxidation; Membrane Potentials; Mitochondria; Nucleosomes; Organometallic Compounds; Protein Transport; Rats; Rats, Wistar; Reactive Oxygen Species; Subcellular Fractions

2005
Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro.
    Journal of cancer research and clinical oncology, 2006, Volume: 132, Issue:2

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Antimalarials; Artemisinins; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Gamma Rays; Glioma; Glutathione Transferase; Humans; Radiation-Sensitizing Agents; Reactive Oxygen Species; Sesquiterpenes; Transferrin; Tumor Stem Cell Assay

2006
Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells.
    Cancer research, 2006, Feb-15, Volume: 66, Issue:4

    Topics: Acetylcysteine; Cell Line, Tumor; Cobalt; Free Radicals; Glioma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Xanthine Oxidase

2006
Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Implants; Female; Glioma; Gliosarcoma; Infusions, Intralesional; Neoplasms, Experimental; Polymers; Rats; Rats, Inbred F344

2006
Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress.
    Free radical biology & medicine, 2007, Mar-15, Volume: 42, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Brain Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Radiation; Glioma; Glutathione; Hydrogen Peroxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2007
Signaling pathways involved in antioxidant control of glioma cell proliferation.
    Free radical biology & medicine, 2007, Jun-01, Volume: 42, Issue:11

    Topics: Acetylcysteine; Animals; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Glioma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Up-Regulation

2007
Inhibition of glioma cell line A-172 MMP activity and cell invasion in vitro by a nutrient mixture.
    Medical oncology (Northwood, London, England), 2007, Volume: 24, Issue:2

    Topics: Acetylcysteine; Amino Acids; Antineoplastic Agents; Arginine; Ascorbic Acid; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Drug Combinations; Glioma; Humans; Laminin; Lysine; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Neoplasm Invasiveness; Plant Extracts; Proline; Proteoglycans

2007
Glioma regression in vitro and in vivo by a suicide combined treatment.
    Molecular cancer research : MCR, 2008, Volume: 6, Issue:3

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenine; Animals; Brain Neoplasms; Cell Death; Dogs; Drug Therapy, Combination; Glioma; Glucose Oxidase; Hydrogen Peroxide; Nitriles

2008
Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Buthionine Sulfoximine; Cell Survival; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Glutathione; Kinetics; Rats; Thioctic Acid; Tumor Cells, Cultured

1997
Active oxygen-mediated chromosomal 1-2 Mbp giant DNA fragmentation into internucleosomal DNA fragmentation in apoptosis of glioma cells induced by glutamate.
    Free radical biology & medicine, 1998, Volume: 24, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Catalase; Chromosomes; Deferoxamine; DNA Fragmentation; Free Radical Scavengers; Glioma; Glutamic Acid; Glutathione; Hydrogen Peroxide; Iron Chelating Agents; Oxidation-Reduction; Oxygen; Phenanthrolines; Rats; Tumor Cells, Cultured

1998
Effect of glutathione-modulating compounds on hydrogen-peroxide-induced cytotoxicity in human glioblastoma and glioma cell lines.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:11-12

    Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glioblastoma; Glioma; Glutathione; Humans; Hydrogen Peroxide; Tumor Cells, Cultured

1997
Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetylcysteine; Adrenoleukodystrophy; Animals; Astrocytes; Brain Chemistry; Cell Survival; Culture Media, Serum-Free; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids; Free Radical Scavengers; Genetic Linkage; Glioma; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Microglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Oxidation-Reduction; Rats; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; X Chromosome

1998
Effect of dietary vitamin A or N-acetylcysteine on ethylnitrosourea-induced rat gliomas.
    Journal of neuro-oncology, 1998, Volume: 40, Issue:1

    Topics: Acetylcysteine; Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Free Radical Scavengers; Glioma; Neuroectodermal Tumors; Pregnancy; Rats; Rats, Sprague-Dawley; Survival Analysis; Vitamin A

1998
Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1999, Volume: 9, Issue:3

    Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Glioma; Glycoproteins; Humans; Kinetics; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Serine Proteinase Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes.
    Brain research. Molecular brain research, 1999, Nov-10, Volume: 73, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Animals; Ascorbic Acid; Astrocytes; Catechol O-Methyltransferase Inhibitors; Catechols; Cell Line; Cycloheximide; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Membrane Proteins; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; RNA, Messenger; Selegiline; Time Factors; Tumor Cells, Cultured

1999
Inhibitory and stimulatory effects of lactacystin on expression of nitric oxide synthase type 2 in brain glial cells. The role of Ikappa B-beta.
    The Journal of biological chemistry, 2000, Aug-11, Volume: 275, Issue:32

    Topics: Acetylcysteine; Animals; Astrocytoma; Brain; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glioma; Humans; I-kappa B Proteins; Inflammation; Interferons; Interleukin-1; Kinetics; Neuroglia; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Rats; Recombinant Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2000
Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release.
    Journal of neurochemistry, 2000, Volume: 75, Issue:6

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Caspases; Cell Survival; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Dose-Response Relationship, Drug; Fas Ligand Protein; fas Receptor; Glioma; Humans; Lactams; Leupeptins; Membrane Glycoproteins; Mice; Mitochondria; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; Transgenes; Tumor Cells, Cultured

2000
Role of ceramide during cisplatin-induced apoptosis in C6 glioma cells.
    Journal of neuro-oncology, 2001, Volume: 52, Issue:1

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Ceramides; Cisplatin; Drug Synergism; Endocannabinoids; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Ethanolamines; Glioma; Glutathione; Microscopy, Electron; Oleic Acids; Rats; Tumor Cells, Cultured

2001
Proteasome inhibitors induce Fas-mediated apoptosis by c-Myc accumulation and subsequent induction of FasL message in human glioma cells.
    FEBS letters, 2001, Aug-24, Volume: 504, Issue:1-2

    Topics: Acetylcysteine; Apoptosis; Base Sequence; Brain Neoplasms; Cysteine Proteinase Inhibitors; DNA Primers; Fas Ligand Protein; fas Receptor; Glioma; Humans; Leupeptins; Membrane Glycoproteins; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured

2001