Compounds > acetylcysteine

acetylcysteine and Friedreich Disease

acetylcysteine has been researched along with Friedreich Disease in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Bertini, ES; D'Amico, J; La Rosa, P; Petrillo, S; Piemonte, F1
Chiang, S; Huang, MLH; Richardson, DR1
D'Autréaux, B; Martin, E; Monnier, V; Russi, M; Tixier, L; Tricoire, H1
Johnson, WM; Mieyal, JJ; Wilson-Delfosse, AL1

Reviews

1 review(s) available for acetylcysteine and Friedreich Disease

ArticleYear
Dysregulation of glutathione homeostasis in neurodegenerative diseases.
    Nutrients, 2012, Oct-09, Volume: 4, Issue:10

    Topics: Acetylcysteine; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Friedreich Ataxia; Glutathione; Homeostasis; Humans; Huntington Disease; Neurodegenerative Diseases; Parkinson Disease

2012

Other Studies

3 other study(ies) available for acetylcysteine and Friedreich Disease

ArticleYear
Targeting NRF2 for the Treatment of Friedreich's Ataxia: A Comparison among Drugs.
    International journal of molecular sciences, 2019, Oct-21, Volume: 20, Issue:20

    Topics: Acetylcysteine; Biopsy; Down-Regulation; Drug Evaluation, Preclinical; Frataxin; Friedreich Ataxia; Humans; Iron-Binding Proteins; Isothiocyanates; Molecular Targeted Therapy; NF-E2-Related Factor 2; Oxidation-Reduction; Signal Transduction; Sulfoxides; Time Factors; Transcriptional Activation

2019
Treatment of dilated cardiomyopathy in a mouse model of Friedreich's ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis.
    Pharmacological research, 2020, Volume: 159

    Topics: Acetylcysteine; Animals; Basic-Leucine Zipper Transcription Factors; Cardiomyopathy, Dilated; Cell Line, Tumor; Disease Models, Animal; Frataxin; Friedreich Ataxia; Gene Expression Regulation; Humans; Iron-Binding Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Mice, Knockout; MicroRNAs; Myocytes, Cardiac; NF-E2-Related Factor 2; Sulfoxides

2020
A Drosophila model of Friedreich ataxia with CRISPR/Cas9 insertion of GAA repeats in the frataxin gene reveals in vivo protection by N-acetyl cysteine.
    Human molecular genetics, 2020, 10-10, Volume: 29, Issue:17

    Topics: Acetylcysteine; Animals; CRISPR-Cas Systems; Disease Models, Animal; Drosophila melanogaster; Frataxin; Friedreich Ataxia; Humans; Introns; Iron-Binding Proteins; Oxidative Stress; RNA-Seq; Trinucleotide Repeat Expansion

2020