acetylcysteine and Experimental Neoplasms

acetylcysteine has been researched along with Experimental Neoplasms in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's1 (4.76)18.2507
2000's3 (14.29)29.6817
2010's13 (61.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bao, L; Chen, Q; Han, J; He, L; Huang, L; Li, B; Liu, H; Liu, X; Ma, K1
Ciekot, J; Gajda, A; Gajda, T; Goszczyński, TM; Janczewski, Ł; Oleksyszyn, J; Psurski, M; Świtalska, M; Wietrzyk, J; Winiarski, Ł1
Ahmed, AU; Auffinger, B; Kim, CK; Lesniak, MS; Moon, KS; Tobias, AL; Ulasov, IV1
Hayashi, J; Imanishi, H; Ishikawa, K; Kikkawa, Y; Morimoto, M; Nakada, K; Takenaga, K; Takibuchi, G; Toyama-Sorimachi, N1
Akaike, T; Aoi, J; Endo, M; Fukushima, S; Hirakawa, S; Horiguchi, H; Ihn, H; Jinnin, M; Kadomatsu, T; Masuda, T; Miyata, K; Odagiri, H; Ogata, A; Oike, Y; Sawa, T1
Muldoon, LL; Neuwelt, EA; Pagel, MA; Wu, YJ1
Bjartell, A; Canesin, G; Escobar, Z; Evans-Axelsson, S; Hellsten, R; Johansson, MH; Sterner, O1
Garrett-Mayer, E; Mehrotra, S; Nishimura, MI; Scheffel, MJ; Scurti, G; Simms, P; Voelkel-Johnson, C1
Grdina, DJ; Miller, RC; Murley, JS; Rademaker, AW; Senlik, RR1
Harashima, H; Kogure, K; Moriguchi, R; Nakamura, T; Shastri, N1
Cooper, CR; Dang, CV; Deck, LM; Dinavahi, R; Gouw, AM; Le, A; Maitra, A; Royer, RE; Semenza, GL; Vander Jagt, DL1
Chodaparambil, JV; Felsher, DW; Huang, M; Kusler, B; Mitchell, BS; Pollyea, DA; Whang, P; Xu, L1
Chang, FR; Chen, HM; Cheng, YJ; Hsieh, KC; Hsieh, YC; Lin, AS; Tsai, LM; Wu, YC; Yuan, SS1
Anastasiou, D; Asara, JM; Auld, DS; Bellinger, G; Boxer, MB; Cantley, LC; Jiang, JK; Locasale, JW; Poulogiannis, G; Sasaki, AT; Shen, M; Thomas, CJ; Vander Heiden, MG1
Maru, Y; Tsukahara, F; Zhang, Q1
Brem, H; DiMeco, F; Fiorindi, A; Gaini, SM; Legnani, FG; Olivi, A; Pradilla, G; Recinos, PF; Thai, QA; Tyler, BM1
Boerth, RC; Olson, RD; Stroo, WE1
Levy, L; Vredevoe, DL1
Balansky, RM; Coscia, N; D'Agostini, F; De Flora, S; Izzotti, A; Scatolini, L1
Chan, A; Landre, P; Marafino, BJ; Winkelhake, JL; Zimmerman, RJ1
Kline, I1

Other Studies

21 other study(ies) available for acetylcysteine and Experimental Neoplasms

ArticleYear
Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity.
    European journal of medicinal chemistry, 2016, Mar-23, Volume: 111

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Tumor Cells, Cultured

2016
Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology.
    Bioorganic & medicinal chemistry letters, 2018, 08-15, Volume: 28, Issue:15

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Humans; Isothiocyanates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neoplasms, Experimental; Phosphorus; Spectrophotometry, Infrared

2018
N-acetylcysteine amide augments the therapeutic effect of neural stem cell-based antiglioma oncolytic virotherapy.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2013, Volume: 21, Issue:11

    Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Glioma; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplasms, Experimental; Neural Stem Cells; Oncolytic Virotherapy; Oncolytic Viruses; Virus Replication; Xenograft Model Antitumor Assays

2013
Polymorphic mutations in mouse mitochondrial DNA regulate a tumor phenotype.
    Mitochondrion, 2013, Volume: 13, Issue:6

    Topics: Acetylcysteine; Animals; Blotting, Western; DNA, Mitochondrial; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; Neoplasms, Experimental; Polymorphism, Genetic; Reactive Oxygen Species

2013
Angiopoietin-like protein 2 accelerates carcinogenesis by activating chronic inflammation and oxidative stress.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:2

    Topics: Acetylcysteine; Angiopoietins; Animals; Carcinoma, Squamous Cell; DNA Methylation; Gene Expression Regulation, Neoplastic; Inflammation; Male; Mice; Mice, Knockout; MutS Homolog 2 Protein; Neoplasms, Experimental; Oxidative Stress; Promoter Regions, Genetic; Skin Neoplasms

2014
N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Brain Neoplasms; Cells, Cultured; Child; Cisplatin; Disease Models, Animal; Female; Humans; Male; Medulloblastoma; Neoplasm Transplantation; Neoplasms, Experimental; Neuroblastoma; Oxidative Stress; Rats; Rats, Nude

2015
Preclinical Characterization of 3β-(N-Acetyl l-cysteine methyl ester)-2aβ,3-dihydrogaliellalactone (GPA512), a Prodrug of a Direct STAT3 Inhibitor for the Treatment of Prostate Cancer.
    Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Prodrugs; Prostatic Neoplasms; STAT3 Transcription Factor; Structure-Activity Relationship; Tumor Cells, Cultured

2016
Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death.
    Cancer research, 2016, 10-15, Volume: 76, Issue:20

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Nucleus; Cells, Cultured; DNA Damage; Female; Humans; Immunotherapy, Adoptive; Lymphocyte Activation; Mice; Neoplasms, Experimental; Phosphorylation; Receptors, Antigen, T-Cell; T-Lymphocytes; Tumor Suppressor Protein p53

2016
Altered expression of a metformin-mediated radiation response in SA-NH and FSa tumor cells treated under in vitro and in vivo growth conditions.
    International journal of radiation biology, 2017, Volume: 93, Issue:7

    Topics: Acetylcysteine; Animals; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Emodin; Female; Metformin; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Suppressor Protein p53

2017
Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:8

    Topics: Acetylcysteine; Amiloride; Animals; Antigen Presentation; Bone Marrow Cells; Cell Line, Tumor; Cells, Cultured; Dendritic Cells; Flow Cytometry; Histocompatibility Antigens Class I; Intracellular Space; Liposomes; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Neoplasms, Experimental; Nocodazole; Oligopeptides; Tumor Burden

2008
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-02, Volume: 107, Issue:5

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Cell Death; Cell Line, Tumor; Energy Metabolism; Enzyme Inhibitors; Female; Glycolysis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Male; Mice; Mice, Nude; Mice, SCID; Naphthalenes; Neoplasm Transplantation; Neoplasms, Experimental; Oxidative Stress; RNA, Small Interfering; Transplantation, Heterologous

2010
Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.
    The Journal of biological chemistry, 2011, Apr-01, Volume: 286, Issue:13

    Topics: Acetylcysteine; Animals; Blast Crisis; Carrier Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Cysteine Proteinase Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Leukemic; GTP-Binding Proteins; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leupeptins; Lymphoma; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Neoplasms, Experimental; Nuclear Proteins; Oxidants; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Multimerization; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins

2011
A novel synthetic protoapigenone analogue, WYC02-9, induces DNA damage and apoptosis in DU145 prostate cancer cells through generation of reactive oxygen species.
    Free radical biology & medicine, 2011, May-01, Volume: 50, Issue:9

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclohexanones; DNA Damage; Flavones; Gene Expression; Histones; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; Neoplasms, Experimental; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Suppressor Protein p53

2011
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses.
    Science (New York, N.Y.), 2011, Dec-02, Volume: 334, Issue:6060

    Topics: Acetylcysteine; Amino Acid Substitution; Animals; Antioxidants; Cell Line; Cell Line, Tumor; Cell Survival; Cysteine; Diamide; Enzyme Activators; Glucose; Glutathione; Humans; Mice; Mice, Nude; Mutant Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Protein Subunits; Pyruvate Kinase; Reactive Oxygen Species; Transplantation, Heterologous

2011
N-acetyl-cysteine enhances growth in BCR-ABL-transformed cells.
    Cancer science, 2005, Volume: 96, Issue:4

    Topics: Acetylcysteine; Animals; Blotting, Western; Cell Line, Transformed; Cell Transformation, Neoplastic; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, abl; Genes, ras; HSP90 Heat-Shock Proteins; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Oncogene Proteins v-abl; Protein-Tyrosine Kinases; Rats

2005
Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.
    Journal of neuro-oncology, 2006, Volume: 77, Issue:3

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Implants; Female; Glioma; Gliosarcoma; Infusions, Intralesional; Neoplasms, Experimental; Polymers; Rats; Rats, Inbred F344

2006
Influence of N-acetylcysteine on the antitumor activity of doxorubicin.
    Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1

    Topics: Acetylcysteine; Animals; Body Weight; Cysteamine; DNA; Doxorubicin; Drug Interactions; Free Radicals; Leukemia P388; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Oxidation-Reduction

1983
The effect of N-acetylcysteine on cyclophosphamide immunoregulation and antitumor activity.
    Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1

    Topics: Acetylcysteine; Animals; Cyclophosphamide; Cystitis; Drug Interactions; Graft vs Host Reaction; Hypersensitivity, Delayed; Lethal Dose 50; Lymphocyte Activation; Lymphoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Rats; Urinary Bladder

1983
Chemoprevention of smoke-related DNA adduct formation in rat lung and heart.
    Carcinogenesis, 1992, Volume: 13, Issue:11

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Animals; Carcinogens; DNA; Heart; Lung; Male; Neoplasms, Experimental; Nicotiana; Plants, Toxic; Rats; Rats, Sprague-Dawley; Smoke

1992
The role of oxidant injury in tumor cell sensitivity to recombinant human tumor necrosis factor in vivo. Implications for mechanisms of action.
    Journal of immunology (Baltimore, Md. : 1950), 1989, Feb-15, Volume: 142, Issue:4

    Topics: Acetylcysteine; Animals; Female; Free Radicals; Glutathione; Humans; Lipid Peroxides; Maleates; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen; Rats; Rats, Inbred Strains; Recombinant Proteins; Tumor Necrosis Factor-alpha

1989
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
    Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1

    Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes

1974