acetylcysteine has been researched along with Encephalopathy, Traumatic in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (64.71) | 24.3611 |
| 2020's | 6 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| Balosso, S; Bañuelos, I; Das Gupta, S; Hämäläinen, E; Hiltunen, M; Kajevu, N; Kyyriäinen, J; Lara, L; Lipponen, A; Natunen, T; Pitkänen, A; Puhakka, N; Ravizza, T; Vezzani, A | 1 |
| Dhamne, SC; Hameed, MQ; Hensch, TK; Hodgson, N; Jannati, A; Lee, HHC; MacMullin, PC; Pascual-Leone, A; Rotenberg, A | 1 |
| Bell, MJ; Clark, RSB; Empey, PE; Kochanek, PM | 1 |
| Bar-Klein, G; Friedman, A; Hameed, MQ; Jozwiak, S; Kaminski, RM; Klein, P; Klitgaard, H; Koepp, M; Löscher, W; Prince, DA; Rotenberg, A; Twyman, R; Vezzani, A; Wong, M | 1 |
| Celorrio, M; Davies, M; Friess, SH; Rhodes, J; Vadivelu, S | 1 |
| Alexis, A; Bergold, PJ; Nikulina, E; Rahman, SN; Whitney, K | 1 |
| Bergold, PJ; Grin'kina, NM; Haber, M; Hartman, I; Ho, J; Irizarry, R; James, J; Kim, J; Nikulina, E; Ramadani, A; Sangobowale, M | 1 |
| Au, AK; Bayır, H; Bell, MJ; Clark, RSB; Empey, PE; Horvat, CM; Kochanek, PM; Nolin, TD; Poloyac, SM; Rosario, BL; Wisniewski, SR | 1 |
| Becker, RE; Chiang, YH; Greig, NH; Hoffer, BJ; Hoffer, ME; Pick, CG | 1 |
| Dai, Z; Shi, H; Wang, L; Wu, P; Zhao, S | 1 |
| Bayir, H; Bell, MJ; Clark, RSB; Empey, PE; Hagos, FT; Kochanek, PM; Ma, X; Poloyac, SM; Wang, P | 1 |
| Ding, K; Fang, J; Wang, HD; Zhou, XM; Zhou, Y; Zhu, L | 1 |
| Bayır, H; Chao, H; Clark, RS; Du, L; Empey, PE; Ji, J; Kochanek, PM | 1 |
| Cheng, W; Du, X; Ewert, DL; Floyd, RA; Kopke, RD; Li, W; Saunders, D; Towner, RA; West, MB | 1 |
| Choi, BY; Jung, HJ; Kho, AR; Kim, IY; Kim, JH; Lee, BE; Lee, SH; Sohn, M; Song, HK; Suh, SW | 1 |
| Hartwell, J; Hiebert, JB; Pierce, JD; Shen, Q; Thimmesch, AR | 1 |
| Chen, W; Guo, Y; Tong, W; Yang, W; Zeng, J; Zheng, P | 1 |
4 review(s) available for acetylcysteine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
N-Acetylcysteine and Probenecid Adjuvant Therapy for Traumatic Brain Injury.
Topics: Acetylcysteine; Blood-Brain Barrier; Brain; Brain Injuries, Traumatic; Child; Humans; Pilot Projects; Probenecid | 2023 |
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
Topics: Acetylcysteine; Animals; Anticonvulsants; Antioxidants; Atorvastatin; Brain Injuries, Traumatic; Ceftriaxone; Dibenzazepines; Drug Repositioning; Epilepsy; Epilepsy, Post-Traumatic; Erythropoietin; Fingolimod Hydrochloride; GABA Agents; Gabapentin; Humans; Immunologic Factors; Inflammation; Interleukin 1 Receptor Antagonist Protein; Isoflurane; Levetiracetam; Losartan; Neuroprotective Agents; Oxidative Stress; Pregabalin; Pyrrolidinones; Sirolimus; Stroke; Topiramate; Translational Research, Biomedical; Vigabatrin | 2020 |
Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Cholinesterase Inhibitors; Drug Repositioning; Humans; Mice; Physostigmine; Psychotropic Drugs; Rats | 2017 |
Systematic Review of Traumatic Brain Injury and the Impact of Antioxidant Therapy on Clinical Outcomes.
Topics: Acetylcysteine; Adult; Amino Acids; Antioxidants; Ascorbic Acid; Brain Injuries, Traumatic; Female; Flavonoids; Humans; Male; Progesterone; Quercetin; Treatment Outcome; Vitamin E | 2016 |
2 trial(s) available for acetylcysteine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Adolescent; Antioxidants; Biomarkers; Body Temperature; Brain Injuries, Traumatic; Child; Child, Preschool; Double-Blind Method; Drug Administration Schedule; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Intracranial Pressure; Intubation, Gastrointestinal; Male; Probenecid; Survival Analysis | 2017 |
Exploratory Application of Neuropharmacometabolomics in Severe Childhood Traumatic Brain Injury.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Adolescent; Brain Injuries, Traumatic; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Humans; Injury Severity Score; Metabolomics; Probenecid | 2018 |
11 other study(ies) available for acetylcysteine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Targeting Oxidative Stress with Antioxidant Duotherapy after Experimental Traumatic Brain Injury.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Injuries, Traumatic; Cell Line; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression; Heme Oxygenase-1; Isothiocyanates; Male; Mice, Inbred C57BL; Microglia; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; Sulfoxides | 2021 |
N-acetylcysteine treatment mitigates loss of cortical parvalbumin-positive interneuron and perineuronal net integrity resulting from persistent oxidative stress in a rat TBI model.
Topics: Acetylcysteine; Animals; Brain Injuries, Traumatic; Interneurons; Oxidative Stress; Parvalbumins; Rats | 2023 |
N-acetylcysteine reduces brain injury after delayed hypoxemia following traumatic brain injury.
Topics: Acetylcysteine; Animals; Axons; Behavior, Animal; Brain Injuries, Traumatic; Fear; Glutathione; Hippocampus; Hypoxia; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Psychomotor Performance; Social Behavior | 2021 |
Delayed dosing of minocycline plus N-acetylcysteine reduces neurodegeneration in distal brain regions and restores spatial memory after experimental traumatic brain injury.
Topics: Acetylcysteine; Animals; Brain; Brain Injuries, Traumatic; Drug Administration Schedule; Drug Therapy, Combination; Free Radical Scavengers; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Minocycline; Neurodegenerative Diseases; Neuroprotective Agents; Spatial Memory | 2021 |
Minocycline plus N-acteylcysteine induces remyelination, synergistically protects oligodendrocytes and modifies neuroinflammation in a rat model of mild traumatic brain injury.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Brain Injuries, Traumatic; Disease Models, Animal; Drug Synergism; Inflammation; Male; Minocycline; Oligodendroglia; Rats; Rats, Sprague-Dawley; Remyelination | 2018 |
Lack of mitochondrial ferritin aggravated neurological deficits via enhancing oxidative stress in a traumatic brain injury murine model.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Injuries, Traumatic; Cognitive Dysfunction; Disease Models, Animal; Ferritins; Glutathione; Malondialdehyde; Memory Disorders; Mice; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Nitric Oxide; Oxidative Stress; Superoxide Dismutase | 2017 |
N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury.
Topics: Acetylcysteine; Animals; Antioxidant Response Elements; Antioxidants; Apoptosis; Behavior, Animal; Brain; Brain Injuries, Traumatic; Caspase 3; Disease Models, Animal; Heme Oxygenase-1; Male; Membrane Proteins; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); Nerve Degeneration; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Time Factors | 2018 |
Probenecid and N-Acetylcysteine Prevent Loss of Intracellular Glutathione and Inhibit Neuronal Death after Mechanical Stretch Injury In Vitro.
Topics: Acetylcysteine; Animals; Brain Injuries, Traumatic; Cell Death; Cells, Cultured; Female; Glutathione; Male; Neurons; Neuroprotective Agents; Probenecid; Rats; Rats, Sprague-Dawley; Stress, Mechanical | 2016 |
Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury.
Topics: Acetylcysteine; Animals; Antioxidants; Benzenesulfonates; Blast Injuries; Brain Injuries, Traumatic; Cytoprotection; Disease Models, Animal; Hippocampus; Male; Neuroprotective Agents; Protein Aggregation, Pathological; Rats; Rats, Long-Evans; tau Proteins | 2016 |
Decreased cysteine uptake by EAAC1 gene deletion exacerbates neuronal oxidative stress and neuronal death after traumatic brain injury.
Topics: Acetylcysteine; Animals; Brain Injuries, Traumatic; Cell Death; Excitatory Amino Acid Transporter 3; Gene Deletion; Mice; Mice, Knockout; Neurons; Oxidative Stress | 2016 |
Connexin40 correlates with oxidative stress in brains of traumatic brain injury rats.
Topics: Acetylcysteine; Analysis of Variance; Animals; Brain; Brain Edema; Brain Infarction; Brain Injuries, Traumatic; Connexins; Disease Models, Animal; Gap Junction alpha-5 Protein; Gene Expression Regulation; Male; Oxidative Stress; Rats; Rats, Wistar; Time Factors | 2017 |