acetylcysteine and Dry Eye

acetylcysteine has been researched along with Dry Eye in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's5 (41.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Bai, Y; Cao, X; Chen, P; Di, G; Wang, D; Wang, Y; Zhang, K; Zhao, H1
Hoeller, S; Knoetzl, W; Nepp, J; Prinz, A; Prinz, M1
Choi, KR; Han, KE; Jun, RM; Lee, SM1
Crist, AJ1
Baumgartner, R; Garhöfer, G; Höller, S; Kaya, S; O'Rourke, M; Peterson, W; Prinz, M; Schmetterer, L; Schmidl, D; Unterhuber, A; Werkmeister, R; Witkowska, KJ; Wolter, A1
Dua, HS; Messina, M1
Eom, Y; Kang, B; Kim, HM; Lee, HK; Li, X; Song, JS; Woo, IH1
Chen, W; Hua, S; Qu, J; Reinach, PS; Ren, Y; She, Y; Xiao, B; Zheng, Q1
Chen, W; Lu, H; Qu, J; Reinach, PS; Ren, Y; Xiao, B; Zheng, Q; Zhu, Y1
Chae, JJ; Chuck, RS; Hongyok, T; Li, L; Na, D; Shin, YJ1
Baggiani, A; Carelli, V; Di Colo, G; Serafini, MF; Zambito, Y1
Bradić, M; Petricek, G; Petricek, I; Pokupec, R; Popović-Suić, S; Sikić, J1

Trials

1 trial(s) available for acetylcysteine and Dry Eye

ArticleYear
A Controlled, Randomized Double-Blind Study to Evaluate the Safety and Efficacy of Chitosan-N-Acetylcysteine for the Treatment of Dry Eye Syndrome.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2017, Volume: 33, Issue:5

    Topics: Acetylcysteine; Adult; Chitosan; Cohort Studies; Double-Blind Method; Dry Eye Syndromes; Female; Humans; Male; Tears; Tomography, Optical Coherence

2017

Other Studies

11 other study(ies) available for acetylcysteine and Dry Eye

ArticleYear
Aquaporin5 Deficiency Aggravates ROS/NLRP3 Inflammasome-Mediated Pyroptosis in the Lacrimal Glands.
    Investigative ophthalmology & visual science, 2023, 01-03, Volume: 64, Issue:1

    Topics: Acetylcysteine; Animals; Caspase 1; Cell Line; Dry Eye Syndromes; Inflammasomes; Lacrimal Apparatus; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Reactive Oxygen Species

2023
Management of moderate-to-severe dry eye disease using chitosan-N-acetylcysteine (Lacrimera®) eye drops: a retrospective case series.
    International ophthalmology, 2020, Volume: 40, Issue:6

    Topics: Acetylcysteine; Adult; Aged; Chitosan; Dry Eye Syndromes; Female; Follow-Up Studies; Humans; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Tears; Treatment Outcome; Young Adult

2020
Clinical Manifestation and Risk Factors Associated With Remission in Patients With Filamentary Keratitis.
    American journal of ophthalmology, 2020, Volume: 218

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Brain Diseases; Child; Dry Eye Syndromes; Eye Injuries; Female; Fluorescein; Follow-Up Studies; Free Radical Scavengers; Humans; Keratitis; Male; Middle Aged; Ophthalmologic Surgical Procedures; Remission Induction; Retrospective Studies; Risk Factors; Serum; Slit Lamp Microscopy

2020
Case Report: Management of Refractory Filamentary Keratitis with N-acetylcysteine.
    Optometry and vision science : official publication of the American Academy of Optometry, 2021, 06-01, Volume: 98, Issue:6

    Topics: Acetylcysteine; Aged; Cornea; Dry Eye Syndromes; Humans; Keratitis; Male; Tears

2021
Early results on the use of chitosan-N-acetylcysteine (Lacrimera
    International ophthalmology, 2019, Volume: 39, Issue:3

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Chitosan; Dry Eye Syndromes; Female; Follow-Up Studies; Humans; Keratitis; Lubricant Eye Drops; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Time Factors; Treatment Outcome

2019
Effects of Topical Mucolytic Agents on the Tears and Ocular Surface: A Plausible Animal Model of Mucin-Deficient Dry Eye.
    Investigative ophthalmology & visual science, 2018, 06-01, Volume: 59, Issue:7

    Topics: Acetylcysteine; Administration, Ophthalmic; Animals; Cell Count; Conjunctiva; Cornea; Disease Models, Animal; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Expectorants; Goblet Cells; Male; Microscopy, Electron, Scanning; Mucin 5AC; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tears

2018
Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.
    Experimental eye research, 2014, Volume: 125

    Topics: Acetylcysteine; Analysis of Variance; Animals; Carrier Proteins; Caspase 1; Conjunctiva; Cornea; Disease Models, Animal; Disease Progression; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Female; Free Radical Scavengers; Inflammasomes; Interleukin-1beta; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction

2014
Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.
    Experimental eye research, 2015, Volume: 134

    Topics: Acetylcysteine; Adult; Blotting, Western; Carrier Proteins; Caspase 1; Cell Line; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Female; Gene Knockdown Techniques; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Keratitis; Male; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Osmotic Pressure; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Transfection; Young Adult

2015
Effect of chitosan-N-acetylcysteine conjugate in a mouse model of botulinum toxin B-induced dry eye.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2009, Volume: 127, Issue:4

    Topics: Acetylcysteine; Administration, Topical; Animals; Blinking; Botulinum Toxins; Botulinum Toxins, Type A; Chitosan; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; Fluorescent Antibody Technique, Indirect; Fluorometholone; Lacrimal Apparatus; Mice; Mice, Inbred CBA; Ophthalmic Solutions; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tears

2009
Methyl-DEAE-dextran: a candidate biomaterial.
    Bio-medical materials and engineering, 2004, Volume: 14, Issue:4

    Topics: Acetylcysteine; Biocompatible Materials; DEAE-Dextran; Drug Delivery Systems; Dry Eye Syndromes; Humans; Hydrogels; Hydrogen-Ion Concentration; Materials Testing; Methylation; Ophthalmic Solutions

2004
[Comparison of local acetylcysteine and artificial tears in the management of dry eye syndrome].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2005, Volume: 59, Issue:4

    Topics: Acetylcysteine; Adult; Aged; Dry Eye Syndromes; Expectorants; Female; Humans; Male; Middle Aged; Ophthalmic Solutions

2005