acetylcysteine has been researched along with Disease Models, Animal in 752 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (0.80) | 18.7374 |
| 1990's | 24 (3.19) | 18.2507 |
| 2000's | 227 (30.19) | 29.6817 |
| 2010's | 422 (56.12) | 24.3611 |
| 2020's | 73 (9.71) | 2.80 |
| Authors | Studies |
|---|---|
| Bray, SM; Chang, S; He, C; Jin, P; Li, Z; Warren, ST; Zarnescu, DC | 1 |
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chen, Y; Li, F; Mei, S; Miao, Y; Song, H; Tan, F; Tang, J; Wang, L; Zhou, J; Zhu, L | 1 |
| Balosso, S; Bañuelos, I; Das Gupta, S; Hämäläinen, E; Hiltunen, M; Kajevu, N; Kyyriäinen, J; Lara, L; Lipponen, A; Natunen, T; Pitkänen, A; Puhakka, N; Ravizza, T; Vezzani, A | 1 |
| Huang, P; Lei, S; Lin, J; Liu, H; Qu, J; Tu, T; Younis, MR; Zhang, DY; Zhu, KS | 1 |
| Billig, H; Brännström, M; Hu, M; Li, J; Liang, M; Ma, H; Ma, S; Sferruzzi-Perri, AN; Shao, LR; Wang, X; Wu, X; Zhang, Y | 1 |
| Ali, T; Arshad, M; Bashir, Z; Fatima, T; Ishtiaq, A; Khan, U; Khan, W; Murtaza, I; Mushtaq, I; Nawaz, M; Sarwar, M; Tabassum, S; Valadi, H | 1 |
| Hu, Z; Liu, X; Lu, X | 1 |
| Citraro, R; Constanti, A; De Caro, C; De Sarro, G; Guarnieri, L; Leo, A; Nicoletti, F; Russo, E; Tallarico, M; Zito, MC | 1 |
| Kamińska, K; Lech, MA; Lorenc-Koci, E; Rogóż, Z | 1 |
| Baskaran, R; Hwu, HG; Lai, CC; Lee, LJ; Liu, CM; Palani, M; Siow, PF; Tsao, CY; Tuan, LH | 1 |
| Abhyankar, S; Adelusi, O; Apte, U; Dawn, B; Duan, L; Jaeschke, H; Nguyen, NT; Ramachandran, A; Robarts, DR; Soder, RP; Umbaugh, DS; Woolbright, B | 1 |
| Bei, Y; Dai, X; Hou, L; Huang, Y; Wu, S; Xu, Y; Zhang, S; Zheng, XL | 1 |
| Babae, JF; Jogataei, MT; Mohammadi, E; Nikbakht, F; Vazifekhah, S | 1 |
| Azak Pazarlar, B; Bilister Egilmez, C; Erbas, O; Erdogan, MA | 1 |
| Beloosesky, R; Ginsberg, Y; Gutzeit, O; Khatib, N; Ross, MG; Weiner, Z; Zmora, O | 1 |
| Deng, YN; He, XL; Li, YF; Wang, LJ; Wang, T; Zhang, YH | 1 |
| Hamid Reza Momeni, -; Matin Ramezani, -; Niloufar Darbandi, -; Samira Moghadasi, - | 1 |
| Benvenutti, R; Chitolina, R; Herrmann, AP; Linazzi, A; Marcon, M; Piato, A; Reis, CG; Stahlhofer-Buss, T | 1 |
| Davidopoulou, S; Kalogirou, TE; Meditskou, S; Pitoulias, AG; Pitoulias, GA; Savvas, I | 1 |
| Gayan-Ramirez, G; Goldberg, P; Hussain, SN; Leduc-Gaudet, JP; Maes, K; Mayaki, D; Moroz, N; Petrof, BJ; Rassier, D; Vassilakopoulos, T | 1 |
| Chakfé, N; Charles, AL; Delay, C; Geny, B; Georg, I; Goupilleau, F; Lejay, A; Talha, S; Thaveau, F | 1 |
| El Hajj, EC; Gardner, JD; Ninh, VK; Ronis, MJ | 1 |
| Burgos, ES; Charron, MJ; Manuel, CR; Munnangi, S; Pekson, R; Reznik, SE; Vuguin, PM; Williams, L | 1 |
| Carlsen, H; Ghoreschi, K; Hailfinger, S; Hartl, D; Kneilling, M; Kramer, D; Mehling, R; Menendez, IG; Öz, HH; Pichler, BJ; Quintanilla-Martinez, L; Röcken, M; Schulze-Osthoff, K; Schwenck, J; Thaiss, WM | 1 |
| Abrigo, J; Aguirre, F; Arrese, M; Cabello-Verrugio, C; Cabrera, D; Marín, T; Simon, F; Tacchi, F; Vilos, C | 1 |
| Bertolo, RF; Brunton, JA; Dodge, ME; Huber, LA; LeDrew, RL; Lee, T | 1 |
| Abid, S; Adnot, S; Attwe, A; Beaulieu, D; Bernard, D; Born, E; Bourachot, B; Breau, M; Collin, G; Czibik, G; Flaman, JM; Houssaini, A; Lipskaia, L; Marcos, E; Mechta-Grigoriou, F; Palazzo, A; Tran Van Nhieu, J | 1 |
| Bagio, E; Barichello, T; Bonfante, SRSA; de Carli, RJ; de Oliveira Junior, AN; de Oliveira, MP; Della Giustina, A; Dos Santos, TM; Engel, NA; Goldim, MPS; Joaquim, L; Kanis, LA; Metzker, KLL; Muttini, S; Novochadlo, M; Petronilho, F; Rezin, GT; Tenfen, L | 1 |
| Hirata, Y; Isagawa, T; Kido, Y; Komuro, I; Manabe, I; Nakagama, Y; Okamura, K; Ono, M; Sakamoto, M; Sato, T; Soma, K; Takeda, N | 1 |
| Albertini, G; Bentea, E; Deneyer, L; Massie, A | 1 |
| Ahlberg, G; Collins, MM; El-Sammak, H; Guenther, S; Hansen, CV; Hellsten, Y; Lundegaard, PR; Marín-Juez, R; Olesen, MS; Piesker, J; Sokol, AM; Stainier, DYR | 1 |
| Lee, SR; Lee, YH | 1 |
| Albulescu, D; Buga, AM; Burada, F; Calina, D; Ciurea, ME; Docea, AO; Iordache, AM; Mamoulakis, C; Mitrut, R; Rogoveanu, OC; Sosoi, S; Tsatsakis, A; Vasile, RC; Zlatian, O | 1 |
| Chen, Y; Deshpande, N; Gupta, R; Jurkunas, UV; Kumar, V; Liu, C; Melangath, G; Miyai, T; Miyajima, T; Mondal, B; Ong Tone, S; Rogan, EG; Vasanth, S; Vojnovic, D; Zahid, M; Zhu, S | 1 |
| Bohle, DS; Coderre, TJ; Fulas, OA; Laferriere, A; Stein, RS | 1 |
| Carmo, PHF; Carvalho, VSD; Costa, MC; de Brito, CB; de Resende-Stoianoff, MA; de Souza, DG; Emídio, ECP; Ferreira, GF; Freitas, GJC; Holanda, RA; Magalhães, TFF; Paixão, TA; Ribeiro, NQ; Rocha, CEV; Santos, DA | 1 |
| Arent, Z; Dobrek, L; Kopanska, M; Nalik-Iwaniak, K; Thor, PJ | 1 |
| Criswell, T; Mouschouris, K; Poteracki, J; Soker, S; Yosef, B; Zhou, Y | 1 |
| Ahamed, AI; Kim, J; Li, X; Martins-Green, M; Wang, Y; Wu, J | 1 |
| Hong, J; Jang, AS; Lee, PH | 1 |
| Hu, H; Li, S; Lu, H; Yang, Y | 1 |
| Chhabra, A; Jain, N; Kumar, B; Kumar, G; Meena, RN; Mishra, S; Prasad, DN; Sethy, NK; Sharma, M; Tulsawani, R | 1 |
| Allen, MR; Avin, K; Chen, N; McNerney, E; Moe, S; Nyman, J; Wallace, J | 1 |
| Bahadır, A; Erduran, E; Eroglu, N; Reis, GP | 1 |
| Chen, J; Chen, T; Chi, X; Deng, Y; Liu, P; Tan, F; Tian, J; Zheng, L | 1 |
| Chen, R; Leng, Y; Li, W; Xia, Z; Xiong, Y; Xue, R | 1 |
| Fan, H; Le, JW; Zhu, JH | 1 |
| Fujita, N; Fujiyoshi, K; Hata, J; Jinzaki, M; Komaki, Y; Matsumoto, M; Nagura, T; Nakamura, M; Nakashima, D; Okano, H; Suzuki, S; Tsuji, T; Watanabe, K | 1 |
| Cui, Y; Hao, H; He, X; Li, X; Liu, L; Liu, Z; Sen, CK; Tian, J; Xiao, Y; Xie, X; Zhang, J | 1 |
| Blair, IA; Devoto, M; Escobar-Zarate, D; Estrada, MA; Gillespie, K; Loomes, KM; Lorent, K; Mesaros, C; Pack, M; Rajagopalan, R; Spinner, NB; Winkler, JD; Zhao, X | 1 |
| Chiang, S; Huang, MLH; Richardson, DR | 1 |
| Li, J; Shi, J; Song, J; Xu, C; Yao, L | 1 |
| Araujo Júnior, E; Cintra, ÁU; Martins, JL; Montero, EFS; Moron, AF; Silvares, SG; Simões, MJ | 1 |
| Astorga, C; Báez-Matus, X; Bevilacqua, JA; Cárdenas, AM; Caviedes, P; Cea, LA; García-Campos, P; Jara-Gutiérrez, C; Paz-Araos, M; Rodríguez, V | 1 |
| Özer, Ö; Şen, M; Topal, U | 1 |
| Ji, Z; Liu, Z; Xia, Z; Xu, H; Xu, R; Xu, S; Zhao, W | 1 |
| Bristow, GC; Dawson, N; Mitchell, EJ; Morris, BJ; Openshaw, RL; Pratt, JA; Thomson, DM | 1 |
| Lian, M; Wang, Y; Wu, S; Zhou, J | 1 |
| D'Autréaux, B; Martin, E; Monnier, V; Russi, M; Tixier, L; Tricoire, H | 1 |
| Ambrogini, P; Bartoccini, F; Cesarini, E; Crinelli, R; De Marchis, F; Di Mambro, T; Diotallevi, A; Fraternale, A; Galluzzi, L; Genovese, DA; Green, K; Luchetti, F; Magnani, M; Manuali, E; Pompa, A; Smietana, M; Zara, C | 1 |
| Abdel-Aziz, AK; Badr, AM; Kassem, DH; Mantawy, EM; Said, RS | 1 |
| Akgun, E; Boyacioglu, M; Kum, S | 1 |
| Chan, AWH; Chan, DPC; Chan, JYW; Ji, X; Lee, SMY; Lee, SS; Leung, RKK; Li, J; Ng, PCI; Ren, Z; Wang, R; Xu, Y; Yew, WW; Zheng, J | 1 |
| Beloosesky, R; Boulos, S; Fainaru, O; Ginsberg, Y; Gutzeit, O; Khatib, N; Millo, Z; Ross, MG; Segal, L; Weiner, Z; Zmora, O | 1 |
| Cao, L; Gui, Y; Tan, Y; Zhang, J; Zheng, Y | 1 |
| Cai, Q; Cheng, W; Du, X; Ewert, DL; Huang, X; Kopke, RD; Li, W; Lu, J; Nakmali, D; West, MB | 1 |
| Bourmaud, M; Capulli, M; Cohen-Solal, M; Forlino, A; Gramegna Tota, C; Maurizi, A; Monti, I; Monti, L; Paganini, C; Rossi, A; Superti-Furga, A; Teti, A; Villani, S | 1 |
| Bennett, M; Falk, MJ; Guha, S; Konkwo, C; Kwon, YJ; Mathew, ND; Nakamaru-Ogiso, E; Ostrovsky, J; Polyak, E; Seiler, C; Xiao, R; Zhang, Z | 1 |
| Du, H; Gao, Y; Li, SJ; Pang, H; Zhou, Y | 1 |
| Chattipakorn, N; Kobroob, A; Kumfu, S; Peerapanyasut, W; Wongmekiat, O | 1 |
| An, L; Li, G; Qu, Y; Wang, J; Ye, W; Zhang, Q; Zhao, X; Zhao, Z; Zheng, D | 1 |
| Cabungcal, JH; Cleusix, M; Conus, P; Cuénod, M; Do, KQ; Dwir, D; Giangreco, B; Jenni, R; Klauser, P; Parietti, E; Steullet, P; Xin, L | 1 |
| Acosta, G; Andrews, KD; Cao, J; Dietrich, AD; Liu, Z; Lu, KH; Lungwitz, EA; Majumdar, S; Race, NS; Shekhar, A; Shi, R; Truitt, WA; Vega Alvarez, SM; Warner, TR | 1 |
| Bakoyiannis, C; Iliopoulos, D; Kapelouzou, A; Liakakos, T; Mastrogeorgiou, M; Mylonas, KS; Nikiteas, N; Schizas, D; Spartalis, E; Spartalis, M | 1 |
| Cabungcal, JH; Cuenod, M; Do, KQ; Grace, AA; Uliana, DL; Zhu, X | 1 |
| Deng, Q; Li, G; Li, M; Song, K; Sun, Y; Wang, J; Zhao, Z; Zheng, D | 1 |
| Haghparast, A; Katebi, SN; Riahi, E; Torkaman-Boutorabi, A; Vousooghi, N | 1 |
| Galus, R; Kopka, M; Paskal, AM; Paskal, W; Pełka, K; Pietruski, P; Quinn, KP; Stachura, A; Wejman, J; Woessner, AE; Włodarski, P | 2 |
| Araújo Montoya, BO; Brum, PO; Campos Soares, M; Carazza Kessler, FG; Castro-Faria-Neto, HC; Dal-Pizzol, F; Fonseca Moreira, JC; Gasparotto, J; Gelain, DP; Góes Valente, WC; Ong, LK; Panzenhagen, AC; Peixoto, DO; Reis, PA; Schirato, GV; Senger, MR; Silva, FP; Telles de Sá Moreira, E | 1 |
| Dou, Q; Gan, H; Tong, H; Yang, Y; Zhang, H | 1 |
| Adaku Chilaka, C; Dekant, R; Langer, M; Lupp, M; Mally, A | 1 |
| Lehnen, TE; Lima, A; Maia, AL; Santos, MV; Wajner, SM | 1 |
| Ganz, T; Jung, G; Monga, SP; Nagarajan, S; Poddar, M; Popovic, B; Preziosi, ME; Singh, S; Valore, EV | 1 |
| Asl, SS; Komaki, A; Sarihi, A; Shahidi, S; Zargooshnia, S | 1 |
| Garner, JP; Lay, DC; Lossie, AC; Radcliffe, JS; Vieira, GLT | 1 |
| Airavaara, M; Albert, K; Myöhänen, TT; Savolainen, MH | 1 |
| Abdalla, IL; Kaooh, S; Mohamed, EA; Sadik, AOE; Zaki, SM | 1 |
| Ercal, N; Karacal, H; Maddirala, Y; Tobwala, S | 1 |
| Chen, ZA; Hsiao, IT; Hsu, CH; Huang, SL; Kung, MP; Lin, KJ; Weng, CC; Wey, SP; Yen, TC | 1 |
| Bak, EJ; Cha, JH; Jang, S | 1 |
| Ali, C; Denis, CV; Diamond, SL; Gakuba, C; Gauberti, M; Herbig, BA; Lenting, PJ; Martinez de Lizarrondo, S; Repessé, Y; Touzé, E; Vivien, D | 1 |
| Amaral, JD; Bernardi, J; Brandão, R; Costa, L; da Costa, M; Fiuza, T; Pereira, ME; Ribeiro, MF; Rodrigues, CMP | 1 |
| Cho, A; Christine, M; Malicdan, V; Miyakawa, M; Nishino, I; Noguchi, S; Nonaka, I | 1 |
| Abramov, AY; Antoine, DJ; Aronica, E; Balosso, S; Del Giudice, E; Liang, LP; Pascente, R; Pastore, A; Patel, M; Pauletti, A; Ravizza, T; Rizzi, M; Salamone, A; Shekh-Ahmad, T; Terrone, G; van Vliet, EA; Vezzani, A; Villa, BR; Walker, MC | 1 |
| Bentzley, J; Fraser, JL; Jenkins, D; Lowe, DW; Martin, R; Nie, X; Rollins, LG; Singh, I | 1 |
| Dong, JY; Gao, W; Liang, JX; Ma, C; Yan, Q | 1 |
| Carr, P; Doman, S; Drummond, GT; Fatemi, A; Garcia, MS; Johnston, MV; Kannan, RM; Kannan, S; Mishra, MK; Nemeth, CL; Wilson, MA; Zhang, F | 1 |
| Ahmadi, F; Daneshmehr, MA; Eshraghi, A; Naderi, J; Nikbakht, M; Talasaz, AH; Vaseghi, G | 1 |
| Bergold, PJ; Grin'kina, NM; Haber, M; Hartman, I; Ho, J; Irizarry, R; James, J; Kim, J; Nikulina, E; Ramadani, A; Sangobowale, M | 1 |
| Manskikh, VN; Pavlenko, TA; Pevzner, IB; Plotnikov, EY; Silachev, DN; Sukhikh, GT; Zorov, DB; Zorova, LD | 1 |
| Adamcova, M; Aziriova, S; Balazova, L; Celec, P; Krajcirovicova, K; Pechanova, O; Repova, K; Simko, F; Tothova, L; Vrankova, S; Zorad, S | 1 |
| Hara, H; Kuse, Y; Nakamura, M; Shimazawa, M; Tsuruma, K | 1 |
| Carret, CK; Carvalho, T; Chora, ÂF; Liehl, P; Marreiros, IM; Mello-Vieira, J; Mota, MM; Zuzarte-Luís, V | 1 |
| Dai, Z; Shi, H; Wang, L; Wu, P; Zhao, S | 1 |
| Chen, JM; Hu, Y; Li, CL; Li, HP; Li, QH; Li, Y; Wang, LS; Weng, D | 1 |
| Head, SI | 1 |
| Ada, S; Burukoglu, D; Cingi, C; Hanci, D; Muluk, NB; Ulusoy, S; Vejselova, D | 1 |
| Shen, JC; Zhang, YC; Zhao, MF | 1 |
| Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F | 1 |
| Abdurasulova, IN; Ekimova, IV; Gazizova, AR; Klimenko, VM; Matsulevich, AV; Pastukhov, YF | 1 |
| Gardner, DK; Truong, T | 1 |
| D'ambros, S; da Rosa Araujo, AS; Herrmann, AP; Marcon, M; Mocelin, R; Piato, A | 1 |
| Liu, C; Xia, Q; Zheng, X | 1 |
| Elson, JL; Kochaj, R; Pienaar, IS; Reynolds, R | 1 |
| Chu, PY; Du, XJ; Fiedler, A; Giam, B; Horlock, D; Kaye, DM; Kiriazis, H; Kuruppu, S; Marques, FZ; Rajapakse, NW; Smith, AI | 1 |
| Blue, ME; Johnston, MV; Kambhampati, SP; Kannan, RM; Kannan, S; Nance, E; Singh, S; Smith, ES; Zhang, F; Zhang, Z | 1 |
| Burns, DP; Murphy, KH; O'Halloran, KD | 1 |
| Bermúdez-Muñoz, JM; García-Alcántara, F; Martínez-Vega, R; Milo, M; Murillo-Cuesta, S; Pulido, S; Rivera, T; Varela-Nieto, I | 1 |
| Li, YH; Wan, RJ | 1 |
| Brooks, HL; Coombes, JS; Gobe, GC; Johnson, DW; Morais, C; Roy, SF; Sanchez, WY; Small, DM | 1 |
| Delignat, S; Dimitrov, JD; Gangadharan, B; Kaveri, SV; Lacroix-Desmazes, S; Peyron, I; Srivastava, A | 1 |
| Beloosesky, R; Efrat, S; Ginsberg, Y; Khatib, N; Mordechai, H; Ross, MG; Sharabi, H; Tamar, BK; Weiner, Z | 1 |
| Chen, Y; Cheng, J; Li, Z; Shen, Y; Wang, W; Zhang, G | 1 |
| Chen, J; Chen, Y; Gong, Y; Hu, F; Huang, G; Jiang, B; Li, M; Peng, Y; Yang, Z; Yin, S; You, B; Yuan, Z; Zhang, Y; Zhao, Y | 1 |
| Erdi, I; Kaya, B; Yasar, M | 1 |
| Archer, DR; Hansen, L; Joseph, G; Lyle, AN; Okwan-Duodu, D; Taylor, WR; Weiss, D | 1 |
| Kurek, K; Maciejczyk, M; Matczuk, J; Waszkiel, D; Zalewska, A; Żendzian-Piotrowska, M; Żukowski, P | 1 |
| Baumbusch, LO; Benterud, T; Henckel, E; Løberg, EM; Manueldas, S; Norgren, S; Rivera, S; Saugstad, OD; Solberg, R | 1 |
| Kim, TW; Moon, JW; Yu, HG | 1 |
| Kimmitt, BA; Moore, GE; Stiles, J | 1 |
| Higashi, K; Igarashi, K; Kashiwagi, K; Kitajima, M; Ko, K; Kogure, N; Sakamoto, A; Sugita, Y; Takao, K; Takayama, H; Terui, Y; Toida, T; Uemura, T; Watanabe, K | 1 |
| McClain, SA; Singer, AJ; Towery, H | 1 |
| Baratashvili, N; Kandelaki, M; Samsonia, M | 1 |
| Blomgren, A; Grundemar, L; Högestätt, ED; Nilsson, JLÅ; Nilsson, UJ | 1 |
| Bonne, G; Decostre, V; Hutchison, CJ; Khouzami, L; Muchir, A; Pecker, F; Pekovic-Vaughan, V; Rodriguez, BM; Varnous, S | 1 |
| Allen, EM; Anderson, CJ; Hughes, EF; Woehrle, NS | 1 |
| Abd-Ellatif, RN; Hegab, II; Sadek, MT | 1 |
| Gu, Y; Huang, LM; Li, G | 1 |
| Eom, Y; Kang, B; Kim, HM; Lee, HK; Li, X; Song, JS; Woo, IH | 1 |
| Aslan, T; Ceylan, B; Ercan, Ç; Kılıç, Ü; Ozansoy, M; Yıldız, P; Yozgat, Y | 1 |
| Faraji, T; Malmir, M; Naderi Noreini, S; Soleimani Mehranjani, M | 1 |
| Gharib, A; Jalaeefar, A; Khandaghy, M; Mohammadi Tofigh, A; Rahimi, MR | 1 |
| Boucher, RC; Delion, MF; Donaldson, SH; Ehre, C; Esther, CR; Fontana, NC; Grubb, BR; Hill, DB; Hothem, LN; Kato, T; Livraghi-Butrico, A; Markovetz, MR; Morrison, CB; Rushton, ZL; Thelin, WR; Villalon, D; Wang, B | 1 |
| Dexter, DT; Harrison, IF; Powell, NM | 1 |
| Hoekstra, LT; Riestiano, B; Saputro, I; Zarasade, L | 1 |
| Pan, L; Tian, H; Wang, Y; Zhang, R | 1 |
| Alin, L; Bourassa, MW; Brand, D; Carmichael, ST; Chen, Y; Colbourne, F; Coppola, G; Darley-Usmar, V; Dietrich, K; Holman, TR; Karuppagounder, SS; Kumar, A; Milne, GL; Nadeau, CA; Perry, S; Pinto, JT; Pratico, D; Ratan, RR; Sanchez, S; Wilkinson, CM | 1 |
| Abe, K; Akazawa, T; Aoki, Y; Eguchi, Y; Fujimoto, K; Furuya, T; Inage, K; Inoue, M; Kanamoto, H; Kinoshita, H; Norimoto, M; Ohtori, S; Orita, S; Shiga, Y; Suzuki, M; Takahashi, K; Umimura, T; Yamauchi, K | 1 |
| Altintop, I; Balcioglu, E; Hanım Yay, A; Karakukcu, C; Ozturk, A; Soyer Sarica, Z; Tatli, M | 1 |
| Guo, H; Mei, L; Pan, JX; Shun, C; Tang, F; Wang, B; Xia, WF; Xiong, F; Xiong, L; Xiong, WC; Zeng, P; Zhao, K | 1 |
| Ayaz, M; Yanardag, SB | 1 |
| Ali, T; Anees, M; da Costa Martins, PA; Duygu, B; Farhan, A; Hamera, S; Jan, MI; Javed, Q; Maryam, S; Murtaza, I; Mushtaq, I; Saba, K; Sultan, A; Tabassum, S | 1 |
| Aparicio-Trejo, OE; Briones-Herrera, A; Hernández-Pando, R; León-Contreras, JC; Pedraza-Chaverri, J; Reyes-Fermín, LM; Sánchez-Lozada, LG; Tapia, E | 1 |
| Cuenca, L; Estrada, C; Fernández-Villalba, E; Gil-Martínez, AL; Herrero, MT; Sánchez, C | 1 |
| Chen, L; Guo, F; Huang, X; Qiao, J | 1 |
| Chen, Y; Li, Y; Wang, T; Zhang, H; Zhang, L | 1 |
| Ding, K; Fang, J; Wang, HD; Zhou, XM; Zhou, Y; Zhu, L | 1 |
| Cao, X; Chen, XZ; Deng, J; Hou, GQ; Li, SSC; Liu, AD; Ren, K; Wu, YS; Zhang, X | 1 |
| Baldwin, GS; Bolton, DM; Ischia, JJ; O'Kane, D; Patel, O | 1 |
| Chattipakorn, N; Kobroob, A; Palee, S; Peerapanyasut, W; Wongmekiat, O | 1 |
| Cho, SG; Im, KI; Jeon, YW; Kim, N; Lee, ES; Lim, JY; Nam, YS; Song, Y | 1 |
| Adiga, V; Majumdar, S; Nandi, D; Raghavan, A; Rananaware, SR | 1 |
| Feng, ZP; Gong, HD; Li, K; Liu, YW; Ou, YC; Peng, JJ; Qi, ST; Qiu, BH; Wang, YJ; Zhou, MF | 1 |
| Guo, X; Harada, C; Harada, T; Kimura, A; Mitamura, Y; Namekata, K; Sano, H; Shitara, H | 1 |
| Bimonte-Nelson, HA; Gipson, CD; Goenaga, J; Koebele, SV; Leyrer-Jackson, JM; McClure, EA; Namba, MD; Phan, S; Piña, J; Powell, GL; Prakapenka, AV | 1 |
| Chen, L; Guo, L; Hou, J; Li, J; Liu, Z; Sun, J; Sun, Y; Wang, Z; Yang, J; Yang, Y; Zhong, A; Zhou, M | 1 |
| Fernandes, J; Gupta, GL | 1 |
| Fei, Q; Liu, K; Liu, M; Wang, H; Wang, K; Wang, N; Xiao, H; Xiao, X; Zhang, H; Zou, J | 1 |
| Calkovska, A; Kolomaznik, M; Kopincova, J; Kosutova, P; Matasova, K; Mikolka, P; Mokra, D; Topercerova, J | 1 |
| Bootkunha, J; Chuncharunee, A; Limjindaporn, T; Panaampon, J; Sreekanth, GP; Suttitheptumrong, A; Yenchitsomanus, PT | 1 |
| da Rosa Araujo, AS; Herrmann, AP; Marcon, M; Mocelin, R; Piato, A | 1 |
| Dawson, PA; Piper, M; Simmons, DG; Zhang, Z | 1 |
| Huang, S; Li, Y; Liang, X; Liu, Y; Wang, K; Wei, H; You, J; Zhang, Y | 1 |
| Abramov, AY; Aronica, E; Balosso, S; Del Giudice, E; Liang, LP; Pascente, R; Pastore, A; Patel, M; Pauletti, A; Ravizza, T; Rizzi, M; Salamone, A; Shekh-Ahmad, T; Terrone, G; van Vliet, EA; Vezzani, A; Villa, BR; Walker, MC | 1 |
| Choo, MS; Heo, J; Ju, H; Kim, S; Lee, S; Lim, J; Ryu, CM; Shin, DM; Shin, JH; Yu, HY | 1 |
| Apaijai, N; Arinno, A; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Keawtep, P; Pratchayasakul, W; Prus, D; Saiyasit, N | 1 |
| Bezerra, JA; Gutta, S; Luo, Z; Mourya, R; Shivakumar, P | 1 |
| Aridon, P; Casari, G; Cittaro, D; De Fusco, M; Fischer, B; Guerrini, R; Lee, WT; Lubarr, N; Lüthy, K; Mackenzie, KM; Mei, D; Meijer, IA; Paesmans, J; Parrini, E; Schoovaerts, N; Swerts, J; Versées, W; Verstreken, P | 1 |
| Chen, J; Chen, M; Huang, H; Li, X; Liu, F; Liu, M; Wang, J; Wu, H | 1 |
| Garcia-Keller, C; Gass, J; Kalivas, PW; Melton, S; Monforton, C; Smiley, C | 1 |
| Garcia-Keller, C; Gipson, CD; Goenaga, JG; Hogue, IB; Kupchik, YM; Namba, MD; Powell, GL; Spencer, SM; Vicino, IA | 1 |
| Elshiekh, M; Kadkhodaee, M; Ranjbaran, M; Seifi, B | 1 |
| Boss, GR; Casteel, DE; Dalton, ND; Gu, Y; Kalyanaraman, H; Lee, S; Makino, A; Milewicz, DM; Patel, HH; Peterson, KL; Pilz, RB; Schilling, JM; Schwaerzer, GK; Wahwah, N; Zhang, Q; Zhuang, S | 1 |
| Lehmann, I; Polte, T; Reiprich, M; Rudzok, S; Schütze, N; Simon, JC; Trump, S | 1 |
| Bell, SP; Chen, Z; Christian, TF; Dauerman, HL; Gibson, PC; Keating, FF; Lachapelle, RR; LeWinter, MM; Meyer, M; Nyotowidjojo, I | 1 |
| Chenni, FZ; Corpet, DE; Guéraud, F; Hobbs, DA; Kunhle, GG; Naud, N; Pierre, FH; Taché, S | 1 |
| Kalivas, P; Post, RM | 1 |
| Jiang, T; Xu, SH; Yu, JF; Yu, QY; Zhang, JX; Zhou, CF; Zhu, QX | 1 |
| Aldbass, AM; Bhat, RS; El-Ansary, A | 1 |
| Fairhall, S; Jenner, J; Jugg, B; Mann, T; Perrott, R; Rutter, S; Salguero, J; Sciuto, AM; Shute, J; Smith, A | 1 |
| Dinelle, K; Doudet, DJ; Flores, J; Jing, Y; Mackey, S | 1 |
| Adil, HS; Afnan, Q; Bhushan, S; Farrukh, MR; Kaiser, PJ; Nissar, AU; Rafiq, RA; Subhash, BC; Tasduq, SA | 1 |
| Abrey-Recalde, MJ; Fernández, GC; Ferrarotti, NF; Gomez, SA; Isturiz, MA; Mejías, MP; Palermo, MS; Panek, CA; Repetto, MG; Vanzulli, S | 1 |
| Baxter, LL; Firnkes, S; Fu, R; Graham, M; Incao, A; Liscum, L; Ory, DS; Pavan, WJ; Porter, FD; Sidhu, R; Wassif, CA; Watkins-Chow, DE; Yanjanin, NM | 1 |
| Qu, CK; Xu, D; Yu, WM; Zheng, H | 1 |
| Cooper, B; Jannasch, A; Park, J; Shi, R; Tully, M; Walls, M; Zheng, L | 1 |
| Berzingi, C; Chen, F; Finkel, MS; Hadfield, JM; Hollander, JM; Miller, DB; Nichols, CE | 1 |
| Chung, BH; Doh, KC; Heo, SB; Jin, L; Kang, SH; Li, C; Lim, SW; Piao, SG; Yang, CW | 1 |
| Ding, B; Hou, Y; Li, J; Liu, Y; Long, M; Wang, L; Wu, G; Yang, Z; Yi, D | 1 |
| Angele, B; Demel, C; Giese, A; Högen, T; Klein, M; Koedel, U; Pfister, HW | 1 |
| Dagdeviren, A; Gulumser, C; Mulayim, B; Onalan, G; Zeyneloglu, H | 1 |
| Arthur, PG; Boyatzis, A; Grounds, MD; Terrill, JR | 1 |
| Brown, RM; Kalivas, PW; Kupchik, YM | 1 |
| Agilli, M; Altayli, E; Aydin, FN; Aydin, I; Cayci, T; Eyi, YE; Kaldirim, U; Macit, E; Taslipinar, MY; Toygar, M; Tuncer, SK; Ucar, F; Yigit, N | 1 |
| Chen, X; Ding, B; Hou, Y; Liu, Y; Long, M; Wang, L; Wang, Q; Wu, G; Yi, D | 1 |
| Buckley, M; Krakauer, T | 1 |
| Abdel Baki, SG; Bergold, PJ; Dash, P; Ershova, A; Grill, RJ; Grin'kina, NM; Haber, M; Irizarry, R; Orsi, S | 1 |
| Bailleux, V; Batonnet-Pichon, S; Briki, F; Delort, F; Gausseres, B; Leccia, E; Segard, BD; Simon, S; Vicart, P | 1 |
| Chen, KL; Dong, X; Liu, ZW; Qiu, C; Wei, J; Xue, JH; Zhu, HT | 1 |
| Bahcecioglu, IH; Demiroren, K; Dogan, Y; Ilhan, S; Kocamaz, H; Ozercan, IH; Ustundag, B | 1 |
| Adcock, I; Bhavsar, P; Chang, Y; Chung, KF; Clarke, C; Li, F; Seiffert, JM; Wiegman, C; Zhang, J; Zhou, X; Zhu, J | 1 |
| Bury, A; Dexter, DT; Elson, JL; Harrison, IF; Pienaar, IS; Simon, AK; Woll, P | 1 |
| Liu, KJ; Shi, H; Taheri, S; Yan, J; Zhang, Z | 1 |
| Chen, TH; Liao, FT; Wang, JC; Wang, JJ; Wu, NC; Yang, YC | 1 |
| Atli, Y; Bulbuloglu, E; Cetinkaya, A; Ciralik, H; Kantarceken, B; Kurutas, EB | 1 |
| Alavi, H; Asri-Rezaee, S; Farshid, AA; Mansouri, S; Najafi, S; Simaee, N; Tamaddonfard, E | 1 |
| Baotic, I; Bienengraeber, M; Bosnjak, ZJ; Kersten, JR; Lazar, J; Muravyeva, M; Sedlic, F; Warltier, DC | 1 |
| Cao, JJ; Picklo, MJ | 1 |
| Cui, X; Li, Z; Wang, G; Wang, S; Wu, P; Yang, F; Yang, X; Yi, X; Zheng, S | 1 |
| Bergo, MO; Ibrahim, MX; Larsson, E; Lindahl, P; Nilsson, JA; Sayin, VI | 1 |
| Assous, M; Gubellini, P; Had-Aissouni, L; Kachidian, P; Kerkerian-Le-Goff, L; Melon, C; Nafia, I; Salin, P | 1 |
| Baumgartner, WA; Beaty, CA; Blue, ME; Johnston, MV; Kambhampati, SP; Kannan, RM; Kannan, S; Lesniak, WG; Mishra, MK; Troncoso, JC; Wilson, MA; Zhang, F | 1 |
| Akan, M; Ergur, BU; Guneli, E; Koca, U; Kume, T; Ocmen, E; Ozkardesler, S; Unal Togrul, B; Uysal, AI | 1 |
| Du, ZZ; Li, L; Sun, X; Wang, CZ; Wu, Q; Yu, HZ | 1 |
| Chan, MH; Chen, HH; Chiang, CC; Chiu, HY; Lee, MY | 1 |
| Białko, M; Filip, M; Frankowska, M; Jastrzębska, J; Nowak, E; Przegaliński, E | 1 |
| Aksu, V; Canbaz, S; Chousein, S; İşcan, Ş; Sağiroğlu, G; Sunar, H; Taştekin, E; Yüksel, V | 1 |
| David, M; Gilhar, A; Keren, A | 1 |
| Karalija, A; Kingham, PJ; Novikov, LN; Novikova, LN; Wiberg, M | 1 |
| Kalra, JK; Kumar, A; Prakash, A | 1 |
| Cheng, J; Hisatome, I; Hu, Y; Huang, T; Li, Z; Luo, C; Luo, Y; Yamamoto, T; Yuan, H; Zhang, Y; Zhu, Y | 1 |
| Goldstein, GA; Pandya, JD; Patel, SP; Pauly, JR; Rabchevsky, AG; Readnower, RD; Sullivan, PG; Yonutas, HM | 1 |
| Cingi, C; Dündar, R; İlknur, AE; İnan, S; Katılmış, H; Muluk, NB | 1 |
| Eldahan, KC; Goldstein, GA; Magnuson, DS; Morehouse, J; Pandya, JD; Patel, SP; Rabchevsky, AG; Sullivan, PG; VanRooyen, JL; Yonutas, HM | 1 |
| Aksit, H; Bildik, A | 1 |
| Chen, W; Hua, S; Qu, J; Reinach, PS; Ren, Y; She, Y; Xiao, B; Zheng, Q | 1 |
| Franklin, T; Li, LP; Lu, J; Papadopoulou, MV; Prasad, PV; Solomon, R; Thacker, J; Zhou, Y | 1 |
| Luo, AY; Ren, JH; Wu, XY; Zhou, YR | 1 |
| Bittner, D; Bueche, CZ; Carare, RO; Garz, C; Härtig, W; Heinze, HJ; Kropf, S; Niklass, S; Reymann, KG; Schreiber, S; Stanaszek, L | 1 |
| Jun, AS; Kim, EC; Meng, H | 1 |
| Li, CH; Liu, BJ; Tian, SF; Wang, CL; Wang, GH; Wei, D; Xu, MJ; Xu, T; Zhang, RH | 1 |
| Dodge, GR; Mauck, RL; Meloni, GR; Mohanraj, B | 1 |
| Brodsky, SV; Hebert, LA; Ivanov, I; Muni, N; Nadasdy, G; Nadasdy, T; Rovin, BH; Satoskar, AA; Vance, JC; Ware, KM | 1 |
| Ghanei, M; Karimzadeh, I; Khalili, H; Saburi, A; Shohrati, M | 1 |
| Akbulut, S; Dogan, Z; Elbe, H; Erdemli, E; Eris, C; Otan, E; Toprak, G; Turkoz, Y | 1 |
| Barbosa de Castro, CM; Dornelas de Andrade, AF; Filho, CA; Galvão, AM; Melo-Junior, MR; Silva, LA; Silva, RA; Souza Maia, MB; Streck, EL; Wanderley, MS | 1 |
| Cabungcal, JH; Calhoon, GG; Counotte, DS; Cuenod, M; Do, KQ; Hong, LE; Kil, J; Lewis, E; O'Donnell, P; Piantadosi, P; Pollock, C; Presgraves, E; Sullivan, E; Tejeda, HA | 1 |
| Eisenbach, C; Hoyler, B; Mogler, C; Sandig, C; Steinebrunner, N; Stremmel, W; Vittas, S | 1 |
| Kishimoto, C; Lee, JD; Shimada, K; Ueda, T; Uzui, H | 1 |
| Andrade, CF; da Rosa, DP; Forgiarini, LA; Forgiarini, LF; Mariano, R; Paludo, Ade O; Silva, MB | 1 |
| Benvenutti, R; Elisabetsky, E; Hidalgo, MP; Levandovski, R; Melo, G; Pilz, LK; Quiles, CL; Trojan, Y | 1 |
| Calkovska, A; Drgova, A; Mokra, D; Mokry, J; Pistekova, H; Tonhajzerova, I; Visnovcova, Z | 1 |
| Antosova, M; Calkovska, A; Drgova, A; Mokra, D; Mokry, J; Petras, M | 1 |
| Akkoc, H; Akkus, M; Kelle, I; Topal, AE; Topal, D; Yilmaz, S | 1 |
| Choi, BY; Kim, HJ; Kim, IY; Kim, JH; Lee, BE; Sohn, M; Suh, SW | 1 |
| Andrade, CF; da Rosa, DP; e Silva, MB; Fiori, CZ; Forgiarini, LF; Marroni, NP; Martinez, D | 1 |
| Lu, L; Pu, LY; Rao, JH; Sun, Y; Wang, XH; Zhang, F | 1 |
| Chen, L; Dong, L; Li, L; Wang, C; Wu, H; Yang, Z; Yuan, W; Zhang, Y | 1 |
| Arab, HA; Cheung, K; Hickman, PE; Kadkhodaee, M; Potter, JM; Roberts, MS; Walker, NI | 1 |
| Muldoon, LL; Neuwelt, EA; Pagel, MA; Wu, YJ | 1 |
| Bauer, N; Bukala, D; Eichner, M; Fuchs, K; Griessinger, CM; Kneilling, M; Pichler, BJ; Röcken, M; Schwenck, J | 1 |
| Fukami, T; Iwamura, A; Kume, T; Nakajima, M; Sasaki, E; Tsuneyama, K; Yokoi, T | 1 |
| Avcı, B; Çavun, S; Savcı, V; Şentürk, T; Serdar, Z; Yermezler, A | 1 |
| Bucht, A; Jonasson, S; Koch, B; Wigenstam, E | 1 |
| Brito, MV; Costa, FD; Costa, LA; Teixeira, RK; Vasconcelos, DM; Yamaki, VN; Yasojima, EY | 1 |
| Churchill, TA; Fortis, S; Khadaroo, RG; Salim, SY; Streutker, C; Zhang, H | 1 |
| Francis, PS; Frazier, AE; Gray, LJ; Hannan, AJ; McGee, SL; Renoir, T; Smith, ZM; Thorburn, DR; Wright, DJ | 1 |
| Hori, M; Ijima, R; Kajiyama, H; Kaneko, H; Kikkawa, F; Mizuno, M; Nagasaka, Y; Nagaya, M; Nakamura, K; Senga, T; Takayama, K; Tanaka, H; Terasaki, H; Ye, F | 1 |
| Antosova, M; Calkovska, A; Drgova, A; Durdik, P; Mokra, D; Mokry, J | 1 |
| Hassanzadeh, K; Izadpanah, E; Khosrobakhsh, F; Moloudi, MR; Rahimmi, A | 1 |
| Chen, Z; Guo, J; Han, M; He, Z; Hu, J; Li, Y; Xu, Y; Zhang, B | 1 |
| Altinoz, E; Turkoz, Y; Vardi, N | 1 |
| Aydın, A; Börcek, P; Karakan, T; Koca, G; Öğüş, E; Sunay, M | 1 |
| Bent, S; Hendren, RL | 1 |
| Chen, X; Chen, Z; Dai, T; Shi, C; Tan, L | 1 |
| Fagundes, M; Fiori, CZ; Kaminski, RS; Marroni, NP; Martinez, D; Martins, EF; Montanari, CC; Rosa, DP | 1 |
| Amboni, RT; Arent, CO; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Quevedo, J; Resende, WR; Steckert, AV; Valvassori, SS | 1 |
| Agostinis, C; Bulla, R; De Leo, R; De Seta, F; Zauli, G; Zorzet, S | 1 |
| Carvalho, EP; da Silva, LF; Dolabela, MF; Green, MD; Moreira, DR; Percário, S; Quadros Gomes, AR; Quadros Gomes, BA; Santos, RS | 1 |
| Elson, JL; Pienaar, IS; Yates, A | 1 |
| Chang, JL; Cheng, CW; Chien, MH; Chow, JM; Hsiao, M; Lai, GM; Lee, LM; Lee, WJ; Lin, YW; Wen, YC | 1 |
| Crum, WR; Dexter, DT; Harrison, IF; Vernon, AC | 1 |
| Deng, J; Gao, B; Kang, Q; Lv, L; Ma, P; Song, X; Xiao, J; Xu, J; Yan, F; Zhang, Y | 1 |
| Abdel-Latif, HA; Ali, MH; Messiha, BA | 1 |
| Friedman, AJ; Landriscina, A; Musaev, T; Nacharaju, P; Nosanchuk, JD; Ray, A; Rosen, J | 1 |
| Erkut, B; Onk, OA | 1 |
| Bellinger, DA; Fletcher, CA; Garner, JP; George, NM; Geronimo, JT; Vieira, G; Whitaker, J | 1 |
| Deng, Y; Guo, X; Liu, H; Pan, Y; Wang, Y; Wang, Z; Yuan, X; Zhu, D | 1 |
| Cohen-Solal, M; De Leonardis, F; Forlino, A; Hay, E; Lecci, S; Monti, L; Paganini, C; Rossi, A; Superti-Furga, A; Tenni, R; Villani, S | 1 |
| Bezuhly, M; Gebremeskel, S; Gillis, J; Hong, P; Johnston, B; MacNeil, LA; Phipps, KD; Sinal, CJ | 1 |
| Akçadağ, A; Gürgen, SG; Korkmaz, F; Sagit, M; Somdaş, MA | 1 |
| Andrus, JP; Herzenberg, LA; Owumi, SE | 1 |
| Le, W; Xiao, Q; Yang, S | 1 |
| Barcellos, LJ; Bevilaqua, F; de Abreu, MS; Elisabetsky, E; Herrmann, AP; Lara, DR; Marcon, M; Mocelin, R; Piato, AL; Rambo, CL; Rohden, A; Zanatta, L | 1 |
| El Kiki, SM; Hasan, HF; Mansour, HH | 1 |
| Cai, Z; Fang, H; Ju, L; Li, E; Lou, Q; Sun, J; Wang, F; Xi, J | 1 |
| Hung, CY; Lee, HP; Li, TM; Liu, SC; Tang, CH; Tsai, CH | 1 |
| Coderre, TJ; Laferrière, A; Nguyen, TM; Poon, AW; Saray, A; Schiller, PW | 1 |
| Acosta, G; Cao, P; Chen, Z; Muratori, B; Park, J; Shi, R; Vega-Alvarez, S; Zheng, L | 1 |
| Diehl, AM; Jewell, ML; Kruger, L; Machado, MV; Michelotti, GA; Moylan, CA; Pereira, Tde A; Xie, G | 1 |
| Cai, GY; Chen, XM; Huang, MJ; Li, P; Li, QP; Wang, N; Wang, R; Wei, RB; Yang, X | 1 |
| Ryba, DM; Solaro, RJ; Wieczorek, DF; Wilder, T; Wolska, BM | 1 |
| Akula, MK; Akyürek, LM; Bergo, MO; Dalin, MG; Ibrahim, MX; Karlsson, C; Le Gal, K; Lindahl, P; Nilsson, J; Sayin, VI; Wiel, C | 1 |
| Durgun, HM; Dursun, R; Guloglu, C; Gunduz, E; İçer, M; Turkcu, G; Üstündağ, M; Yuksel, H; Zengin, Y | 1 |
| Chien, CC; Chiu, YT; Lin, TH; Liu, CC; Liu, RH; Su, HL; Tsai, MS; Wang, SH | 1 |
| Askenazi, D; Cerda, J; de Caestecker, M; Faubel, S; Fissell, WH; Harrell, FE; Humphreys, BD; Liu, KD; Mour, G; Nolin, TD; Okusa, MD; Pullen, N | 1 |
| Dai, Y; Hao, Y; Kogure, Y; Nishiyama, N; Noguchi, K; Tanaka, K; Wang, S; Yamamoto, S | 1 |
| Denton, KR; Li, XJ; Wang, ZB; Xu, CC; Zhang, X | 1 |
| Gupta, S; Kruger, WD | 1 |
| Colares, JR; da Silva, J; Fisher, C; Hartmann, RM; Licks, F; Marques, C; Marroni, NP; Reys, J; Schemitt, E; Soares, Mdo C | 1 |
| Al-Rasheed, NM; Al-Rejaie, S; Al-Samhari, MM; Dzimiri, N; Hasan, IH; Mahmoud, AM | 1 |
| Chen, J; Chen, R; Feng, L; Jiang, Z; Li, X; Lou, J; Xia, H; Xiao, Y; Yin, X; Yu, M; Zhang, X; Zhu, L | 1 |
| Ilic, M; Jakovljevic, V; Joksimovic, J; Mitrovic, S; Orescanin-Dusic, Z; Rosic, G; Selakovic, D; Srejovic, I; Tatalović, N; Zivkovic, V | 1 |
| Andressoo, JO; Härma, MA; Jakobson, M; Karalija, N; Kopra, J; Kumar, A; Kuure, S; Lilleväli, K; Lindahl, M; Marshall, P; Mijatovic, J; Ola, R; Palm, E; Panhelainen, A; Piepponen, TP; Porokuokka, LL; Pulkkinen, N; Saarma, M; Strömberg, I; Tekko, T; Varendi, K; Vilenius, C; Võikar, V | 1 |
| Borlee, BR; Borlee, GI; Ferris, RA; Hennet, ML; Loncar, KD; McCue, PM | 1 |
| Kaur, T; Sharma, M; Singla, SK | 1 |
| Aschner, M; Cao, Z; Chen, J; Luo, W; Su, P; Wang, D; Wang, S; Zhang, J; Zhao, F | 1 |
| Budziszewska, B; Filip, M; Krzyzanowska, W; Pera, J; Pomierny, B | 1 |
| Hou, JQ; Huang, YH; Lv, JX; Pu, JX; Wang, LL; Wei, XD; Yan, CY | 1 |
| Atmaca, HT; Bayir, Y; Canayakin, D; Halici, Z; Keles, MS; Kilic Baygutalp, N; Kocak Ozgeris, FB; Sezen Karaoglan, E | 1 |
| Arkadopoulos, NF; Dimas, C; Karmaniolou, II; Kondi-Pafiti, AI; Lolis, ED; Mylonas, AI; Orfanos, NF; Papalois, AE; Smyrniotis, VE; Stergiou, IP | 1 |
| Baker, DA; Choi, S; Frenkel, MM; Hurley, MM; Maunze, B; Resch, JM | 1 |
| Cheng, W; Du, X; Ewert, DL; Floyd, RA; Kopke, RD; Li, W; Saunders, D; Towner, RA; West, MB | 1 |
| Altay, DU; Alver, A; Bodur, A; İnce, İ; Kahraman, C | 1 |
| Chu, PY; Du, XJ; Giam, B; Horlock, D; Kaye, DM; Kiriazis, H; Kuruppu, S; Rajapakse, NW; Smith, AI | 1 |
| Ahmet, M; Ari, NS; Asli, M; Aynur, S; Esin, Y; Ozgur, T; Selim, D; Suha, T; Süleyman, T; Yunus, K | 1 |
| Blair, I; Gillespie, K; Koo, KA; Lorent, K; Marchione, DM; Pack, M; Porter, JR; Shin, D; So, J; Waisbourd-Zinman, O; Wells, RG; Wilkins, BJ; Zhao, X | 1 |
| Asker, SA; El-Hadidy, AR; El-Mohandes, EM; Ghonaim, FM | 1 |
| Huang, M; Liang, L; Qiu, Q; Shi, M; Xiao, Y; Xu, H; Yang, X; Zeng, S; Zhan, Z; Zou, Y | 1 |
| Bembi, B; Buratti, E; Canterini, S; Dardis, A; Fiorenza, MT; Ghetti, B; Murrell, JR; Newell, KL; Stuani, C; Zampieri, S | 1 |
| Acer, S; Balci, YI; Bozkurt, K; Kucukatay, V; Polat, A; Sarbay, H; Yagci, R | 1 |
| Calkovska, A; Kopincova, J; Kosutova, P; Mikolka, P; Mikusiakova, LT; Mokra, D | 1 |
| Miyake, N; Miyamoto, S | 1 |
| Jędrzejewski, T; Kozak, W; Piotrowski, J; Wrotek, S | 1 |
| Chattipakorn, N; Chattipakorn, SC; Krintratun, W; Sripetchwandee, J; Wongjaikam, S | 1 |
| Hara, H; Nishimura, Y; Saito, Y; Shimazawa, M; Tanaka, T; Tsuruma, K | 1 |
| Bongarzone, ER; Escolar, ML; Gray, SJ; Kafri, T; Sands, MS; Vite, CH | 1 |
| Afaq, F; Agarwal, A; Athar, M; Croutch, CR; Elmets, CA; Li, C; Srivastava, RK; Weng, Z | 1 |
| Bell, RL; Breier, A; Chambers, RA; Engleman, EA; Hulvershorn, LA; Rao, KN; Sentir, AM | 1 |
| Best, R; Bews, H; Bhindi, R; Chaudhary, R; Cheung, D; Goyal, V; Jassal, DS; Mandal, S; Niraula, S; Premecz, S; Ravandi, A; Shaikh, B; Singal, PK; Thliveris, J | 1 |
| Algin, MC; Bayhan, Z; Cosgun, S; Kahraman, C; Kocak, A; Koçak, C; Koçak, FE; Kocak, H; Metineren, MH; Savran, B; Zeren, S | 1 |
| Arkadopoulos, N; Karmaniolou, I; Mani, A; Mylonas, A; Nomikos, T; Orfanos, N; Pafiti, A; Papalois, A; Smyrniotis, V; Staikou, C; Theodoraki, K | 1 |
| Abd-Elbaset, M; Abdel-Bakky, MS; Arafa, EA; El Sherbiny, GA; Elgendy, AN | 1 |
| Benvenutti, R; Elisabetsky, E; Gama, CS; Giongo, F; Herrmann, AP; Noetzold, G; Piato, AL; Santos, P | 1 |
| de Oliveira Menezes, A; Frasson de Souza Montero, E; Lauz Medeiros, SH; Zogbi, L | 1 |
| Chen, LH; Cheng, RX; Gao, YJ; Huang, Y; Liu, T; Liu, TT; Wang, S; Wang, XL; Zhou, FM; Zhou, Y | 1 |
| Amaral, EP; Andrade, BB; Barbosa, T; Conceição, EL; Cordeiro-Santos, M; Costa, DL; D'Império-Lima, MR; Marinho, JM; Rocha, MS; Sher, A | 1 |
| Guo, F; Song, X; Yu, W | 1 |
| De Meyer, SF; Deckmyn, H; Dekimpe, C; Lamprecht, S; Lopez, JA; Pareyn, I; Plaimauer, B; Roodt, J; Tersteeg, C; Van Rensburg, WJ; Vandenbulcke, A; Vandeputte, N; Vanhoorelbeke, K | 1 |
| Ali, DA; Katary, MA; Soliman, NA; Zineldeen, DH | 1 |
| Graham, M; Ivanova, AV; Navaratnam, D; Santos-Sacchi, J; Schettino, A; Song, L; Tan, WJT; Yarbrough, WG | 1 |
| Chen, W; Guo, Y; Tong, W; Yang, W; Zeng, J; Zheng, P | 1 |
| de Fraga, LS; de Souza, JA; Horst, A; Kolberg, C; Partata, WA; Ribeiro, MF; Riffel, AP; Santos, MC | 1 |
| Bentea, E; Churchill, MJ; Deneyer, L; Hood, RL; Massie, A; Meshul, CK; Moore, C; Verbruggen, L | 1 |
| Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alotaibi, MR; AlSaad, AM; Ansari, MA; Nadeem, A | 1 |
| Baumann, J; Bogar, L; Ferencz, A; Ghosh, S; Jancso, G; Roth, E; Szakmany, T | 1 |
| Baltzer, WI; Hosgood, GL; Kerwin, SC; Levine, JM; McMichael, MA; Ruaux, CG; Steiner, JM | 1 |
| Baek, SJ; Eling, TE; Hara, Y; Lee, SH; McEntee, MF; Sukhthankar, M; Yamaguchi, K | 1 |
| Bagh, MB; Banerjee, K; Chakrabarti, S; Jana, S; Maiti, AK; Roy, A | 1 |
| Akaydin, Y; Duru, M; Helvaci, MR; Koç, A; Kuvandik, G; Nacar, A; Oksüz, H; Söğüt, S; Yönden, Z | 1 |
| Abe, M; Ichimaru, S; Kaji, S; Takiguchi, Y; Tsuchiya, K; Wada, K | 1 |
| Shen, YZ; Wu, AR; Xu, CF | 1 |
| Nascimento Saldiva, PH; Rhoden, CR; Saiki, M; Tannhauser Barros, HM; Venturini, CD; Zanchi, AC | 1 |
| Alipour, M; Mitsopoulos, P; Omri, A; Smith, MG; Suntres, ZE; Vermeulen, N | 1 |
| Ciralik, H; Imrek, SS; Kilinc, M; Ozbag, D; Türüt, H | 1 |
| Bilgili, A; Eraslan, G; Onbasilar, I; Ozdemir, M; Yalçin, S | 1 |
| Del Puerto-Nevado, L; González-Mangado, N; Heili Frades, S; Martin-Mosquero, C; Martinez-Galán, L; Peces-Barba Romero, G; Pérez-Rial, S; Rodriguez Nieto, MJ; Rubio, ML | 1 |
| Aboulkassim, T; Fernandes, P; Hamel, E; Lecrux, C; Nicolakakis, N; Ongali, B; Rosa-Neto, P; Tong, XK | 1 |
| Albano, E; Badger, TM; Baumgardner, JN; Hennings, L; Ronis, MJ; Shankar, K | 1 |
| Bandow, K; Kakimoto, K; Machigashira, M; Matsuguchi, T; Matsuyama, T; Ohnishi, T | 1 |
| Baumann, J; Bogár, L; Falusi, B; Gál, J; Ghosh, S; Roth, E | 1 |
| Bru, I; De Muynck, M; Decorte, T; Rimbaut, S; Van Maele, G; Vanden Bossche, LC; Vanderstraeten, G; Wojtowicz, I | 1 |
| Abel, T; Bizily, SF; Esposito, MF; Favilla, C; Kanes, SJ; Kelly, MP; Stein, JM; Vecsey, CG; Wand, G; Yang, X | 1 |
| Fu, JJ; Huang, GD; Liu, YH; Meng, J; You, Y | 1 |
| Güven, A; Korkmaz, A; Kul, M; Ongürü, O; Oter, S; Sarici, U; Topal, T; Tunc, T | 1 |
| Chen, X; Hao, J; Hao, X; Lee, M; Liu, B; Reuhl, KR; Yang, CS; Zhang, B | 1 |
| Cerqueira, NF; Hussni, CA; Padovani, CR; Sequeira, JL; Yoshida, WB | 1 |
| Aslam, S; Darouiche, RO; Hernandez, MD; Mansouri, MD; Zeluff, B | 1 |
| Arikök, AT; Aydin, R; Gökakin, AK; Gömceli, I; Gülbahar, O; Gürer, A; Kulaçoğlu, H; Ozdoğan, M | 1 |
| Gass, JT; Kalivas, PW; Lavin, A; Moran, M; Moussawi, K; Olive, MF; Pacchioni, A | 1 |
| Fu, X; Mei, J; Niu, C; Pan, Q | 1 |
| Betocchi, S; Chen, J; Chen, SN; Efimov, IR; Li, W; Lombardi, R; Marian, AJ; Ripplinger, CM; Rodriguez, G; Wickline, SA; Willerson, JT | 1 |
| Galanopoulou, P; Giannioti, K; Liapi, C; Mikros, E; Papalois, A; Theocharis, S; Zira, A | 1 |
| Bozkurt, D; Duman, S; Hur, E; Nar, H; Purclutepe, O; Sen, S; Sezak, M; Ulkuden, B | 1 |
| Aydin, B; Durmus, M; Erdurmus, M; Karadağ, R; Keskin, U; Yagci, R; Yigitoglu, R; Yilmaz, FM | 1 |
| Boontje, NM; de Crom, R; de Waard, MC; Dekkers, DH; Duncker, DJ; Kuster, DW; Lamers, JM; van der Velden, J; van Haperen, R | 1 |
| Millet, V; Moiola, CP; Pasquini, JM; Pasquini, LA; Soto, EF | 1 |
| Bigam, DL; Cheung, PY; Emara, M; Jewell, LD; Johnson, ST; Korbutt, G; Obaid, L; Slack, G; Van Aerde, J | 1 |
| Cai, S; Chen, JB; Chen, P; Wu, J; Zhang, C | 1 |
| Hofmann, AF; Ikegawa, S; Mitamura, K; Okihara, R; Sakai, T; Sogabe, M; Wakamiya, T; Watanabe, S | 1 |
| Chae, JJ; Chuck, RS; Hongyok, T; Li, L; Na, D; Shin, YJ | 1 |
| Brown, LA; Gabelaia, L; Gauthier, TW; Tang, SM | 1 |
| Kishimoto, C; Kita, T; Lee, JD; Murayama, T; Shimada, K; Ueda, T; Uzui, H; Yokode, M | 1 |
| Liu, XC; Wang, P; Yan, H | 1 |
| Atli, Y; Bulbuloglu, E; Ciralik, H; Dogan, Z; Goksu, M; Kilinc, M; Oksuz, H; Ozkan, OV; Senoglu, N; Yildiz, H; Yuzbasioglu, MF | 1 |
| Bell, SP; Chen, Z; Dauerman, HL; LeWinter, MM; Meyer, M; Selby, DE; Singla, DK | 1 |
| Fischell, TA | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S; Smith, M; Stone, WL | 1 |
| Hamilton, AE; Reid, AJ; Shawcross, SG; Terenghi, G; Wiberg, M | 1 |
| Cardounel, AJ; Carnes, CA; Gyorke, S; Hamlin, RL; Khan, M; Nakayama, T; Nishijima, Y; Sridhar, A; Terentyev, D; Terentyeva, R | 1 |
| Jiang, HN; Qu, JM; Xu, JF; Xu, P; Zhang, HJ; Zhang, J | 1 |
| Igarashi, K; Ishii, I; Kashiwagi, K; Nishimura, K; Okuyama, S; Omura, T; Saiki, R | 1 |
| DI, JF; Feng, Z; Lin, Y; Zeng, S | 1 |
| Feng, R; Huo, L; Li, J; Zhai, W; Zhang, S | 1 |
| Arai, Y; Honjo, K; Imanishi, J; Kishida, T; Kubo, T; Mazda, O; Nakagawa, S; Saito, M; Sakao, K; Takahashi, KA | 1 |
| Chang, E; Jenkins, DD; Singh, I | 1 |
| Chen, F; Chen, PS; Fishbein, MC; Garfinkel, A; Karagueuzian, HS; Lin, SF; Mandel, WJ; Morita, N; Qu, Z; Sovari, AA; Weiss, JN; Xie, LH; Xie, Y | 1 |
| Bae, YJ; Cho, YS; Jang, MK; Kim, TB; Lee, KY; Moon, HB; Moon, KA; Park, CS | 1 |
| Abdelsaid, MA; Al-Shabrawey, M; El-Remessy, AB; Matragoon, S; Pillai, BA; Prakash, R | 1 |
| Balansky, R; De Flora, S; Ganchev, G; Iltcheva, M; Steele, VE | 1 |
| Jang, HS; Kim, J; Park, KM | 1 |
| Bigam, DL; Cheung, PY; Jantzie, LL; Johnson, ST; Todd, KG | 1 |
| Aktaş, BK; Baykam, MM; Bulut, S; Memiş, A; Ozden, C; Senes, M; Yücel, D | 1 |
| Jo, YH; Kim, K; Kim, TY; Kwon, WY; Lee, CC; Lee, JH; Rhee, JE; Singer, AJ; Suh, GJ | 1 |
| Da Silveira, M; Yoshida, WB | 1 |
| Colles, SM; Graham, LM; Miyazaki, K; Rosenbaum, MA | 1 |
| Cui, JH; Li, YL; Li, ZX; Meng, XP; Wang, L; Wang, YW; Yin, CS | 1 |
| Andrades, M; Dal-Pizzol, F; de Oliveira, MR; Fonseca Moreira, JC; Ritter, C; Streck, EL | 1 |
| Abu-Kishk, I; Alkan, Y; Bar-Haim, A; Berkovitch, M; Evans, S; Goldstein, LH; Kozer, E; Petrov, I; Siman-Tov, Y; Weinbaum, S | 1 |
| Gul, M; Imrek, S; Ozdemir, G; Tolun, FI | 1 |
| Albuquerque, RL; de Andrade, GM; de Morais, SM; de Souza, CM; Rao, VS; Rodrigues, Pde A; Santos, FA; Silva, AR; Silva, MG | 1 |
| D'Amore, PA; Fukumoto, A; Hamuro, J; Kajiya, K; Kinoshita, S; Maruyama, K; Walsh, T | 1 |
| Johansson, SM; Modo, MM; Vernon, AC | 1 |
| Cha, MJ; Chang, W; Choi, EJ; Chung, N; Ham, O; Hwang, KC; Jang, Y; Kim, IK; Lee, SY; Lim, S; Song, BW; Song, H | 1 |
| Kodai, S; Kubo, S; Minamiyama, Y; Okada, S; Osada-Oka, M; Shinkawa, H; Suehiro, S; Takemura, S; Tsukioka, T | 1 |
| Chang, HY; Guo, YL; Lee, YH; Pan, MH; Sheu, HM; Wang, BJ; Wang, YJ | 1 |
| Celik, Y; Cigdem, MK; Kizil, G; Kizil, M; Nergiz, Y; Onen, A | 1 |
| Cock, ML; Duncan, JR; Hale, N; Harding, R; Probyn, ME; Rees, SM; Shields, A; Tolcos, M | 1 |
| Bönisch, U; Lehmann, I; Polte, T; Schütze, N; Simon, JC | 1 |
| Başkesen, A; Hanci, V; Kerimoğlu, A; Kiliç, K; Koca, K; Taştekin, D | 1 |
| Bouchier-Hayes, D; Kearns, SR; Kelly, C; O'Briain, DE; Sheehan, KM | 1 |
| de Mello, CF; de Oliveira Ferreira, AP; Ferreira, J; Rossato, MF; Velloso, NA | 1 |
| Bellodi-Privato, M; D'Albuquerque, LA; Junior, RF; Kubrusly, MS; Machado, MC; Molan, NA | 1 |
| Joshi, D; Mittal, DK; Shrivastava, S; Shukla, S | 1 |
| Aktunc, E; Barut, F; Buyukates, M; Demircan, N; Kandemir, O; Ozacmak, HS; Ozacmak, VH | 1 |
| Barbosa, PR; Cardoso, MR; Dal-Pizzol, F; Daufenbach, JF; Gonçalves, CL; Machado, RA; Rezin, GT; Roza, CA; Scaini, G; Schuck, PF; Streck, EL | 1 |
| Cheng, TJ; Guo, YL; Hsu, CJ; Wu, HP | 1 |
| Bémeur, C; Butterworth, RF; Desjardins, P; Vaquero, J | 1 |
| Ichihara, G; Ichihara, S; Itoh, K; Liu, F; Murohara, T; Yamada, Y; Yamamoto, M | 1 |
| Erdi, F; Esen, H; Güney, O; Kiyici, A; Kocaogullar, Y | 1 |
| El Fata, F; Ouelette, V; Robitaille, Y; Saliba, I | 1 |
| Cui, J; Kazlauskas, A; Lei, H; Maberley, D; Matsubara, J; Samad, A; Velez, G | 1 |
| Kim, Y; Klaunig, JE; Misse, A; Monga, SP; Singh, S; Tan, X; Zeng, G; Zhang, XF | 1 |
| Aluise, CD; Butterfield, DA; Huang, Q; Joshi, G; Markesbery, WR; St Clair, DK; Sultana, R | 1 |
| Butler, RN; Campbell, MA; Huynh, HQ; Kritas, S; Lee, SS; Tran, CD | 1 |
| Brunelli, R; Costa, G; Krasnowska, E; Lundeberg, T; Parasassi, T; Pittaluga, E; Porpora, MG; Santucci, D | 1 |
| Andraus, W; Coelho, AM; D'Albuquerque, LA; Galvão, FH; Haddad, LB; Leitão, RM; Machado, MC; Oliveira, MG; Souza, GF | 1 |
| Moldobaeva, A; Nijmeh, J; Wagner, EM | 1 |
| Kuang, FW; Tan, LP; Xu, F | 1 |
| Chen, Y; Dalton, TP; Johansson, E; Miller, ML; Nebert, DW; Orlicky, DJ; Shen, D; Shertzer, HG; Vasiliou, V; Yang, Y | 1 |
| Ishida, S; Kato, N; Kubota, M; Kubota, S; Kurihara, T; Miyashita, H; Noda, K; Ozawa, Y; Shimmura, S; Tsubota, K; Umezawa, K; Usui, T | 1 |
| Baldo, CF; Batalhão, ME; Capellini, VK; Cárnio, EC; Celotto, AC; Evora, PR; Rodrigues, AJ | 1 |
| De la Fuente, M | 1 |
| Amit, T; Bar-Am, O; Prosolovich, K; Weinreb, O; Youdim, MB | 1 |
| Dalic, A; Dart, AM; Drummond, G; Du, XJ; Fang, L; Gao, XM; Kiriazis, H; Ritchie, RH; Sarwar, M; Sim, K; Xu, Q; Zhang, YY | 1 |
| Fukushima, M; Hara, R; Inatani, M; Inomata, Y; Kawaji, T; Sagara, N; Tanihara, H | 1 |
| Cohn, LA; DeClue, AE; Dodam, JR; Guntur, VP; Lee-Fowler, TM; Reinero, CR | 1 |
| Abdel-Rahman, SM; Brown, A; Hinson, JA; James, LP; Letzig, L; McCullough, SS; Milesi-Hallé, A | 1 |
| Altieri, PI; Crespo, MJ; Cruz, N; Escobales, N | 1 |
| Hamatani, H; Hiromura, K; Kuroiwa, T; Maeshima, A; Nojima, Y; Sakairi, T; Takahashi, S; Takeuchi, S; Tomioka, M | 1 |
| Ebrahimi-Fakhari, D; Hyman, BT; McLean, PJ; Unni, VK; Vanderburg, CR | 1 |
| Bezerra, FS; Machado, MN; Pires, KM; Porto, LC; Valença, SS; Zin, WA | 1 |
| Fukaya, H; Imaki, R; Izumi, T; Machida, Y; Niwano, H; Niwano, S; Sasaki, S; Yuge, M | 1 |
| Ali, SF; Bains, M; Clark, RA; Imam, SZ; Kahle, PJ; Li, S; Roberts, JL; Valente, AJ; Yamamoto, A; Zhou, Q | 1 |
| Ito, H; Matsui, H; Takahashi, R; Takeda, S; Taniguchi, Y | 1 |
| Jegatheeswaran, S; Siriwardena, AK | 1 |
| Coutinho, LM; Pereira Filho, Ade A; Pereira Filho, Nde A; Soares, FP | 1 |
| Crum, WR; Johansson, SM; Modo, M; Vernon, AC | 1 |
| Joshi, D; Mittal, D; Shrivastav, S; Shukla, S; Srivastav, AK | 1 |
| Jain, S; Kumar, CH; Mediratta, PK; Suranagi, UD | 1 |
| Adler, BL; Berman, AE; Brennan, AM; Chan, WY; Edling, Y; Kauppinen, TM; Reyes, RC; Suh, SW; Swanson, RA | 1 |
| Campochiaro, PA; Jo, YJ; Lee, SY; Lu, L; Masoudi, S; Oveson, BC; Usui, S; Zafar, AB | 1 |
| Gui, Y; Jiang, Y; Li, H; Li, J; Yin, H; Zheng, XL | 1 |
| Karthikeyan, S; Priya, S; Vijayalakshmi, P; Vivekanandan, P | 1 |
| Bogen, O; Chu, C; Gear, RW; Levine, E; Levine, JD | 1 |
| Crum, A; Crum, AC; French, SW; Kim, H; Kim, HJ; Norris, KC; Rajavashisth, TB; Shen, R; Sinha-Hikim, AP; Sinha-Hikim, I; Vaziri, ND | 1 |
| Berk, M; Bush, AI; Copolov, DL; Dean, OM; Mavros, C; van den Buuse, M | 1 |
| Melo, AC; Nesi, RT; Pimenta, WA; Porto, LC; Rueff-Barroso, CR; Silva, MA; Valença, SS | 1 |
| Basha, RH; Priscilla, DH | 1 |
| Balough, BJ; Clifford, RE; Coleman, JK; Jackson, RL; Kopke, RD; Liu, J | 1 |
| Fujita, M; Iwasaka, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K | 1 |
| Abdullaev, FA | 1 |
| Chen, WC; de la Monte, SM; Longato, L; Petersen, DR; Ronis, M; Setshedi, M; Wands, JR | 1 |
| Arunachalam, S; Hwang, PH; Kim, MS; Kim, SY; Lee, SH; Lee, YH; Yi, HK; Yun, BS | 1 |
| Batteux, F; Brézin, A; Chéreau, C; Daudin, JB; Espy, C; Goulvestre, C; Kavian, N; Monnet, D; Nicco, C; Omri, S; Wang, A; Weill, B | 1 |
| Fan, J; Ji, Z; Liao, J; Liu, H; Peng, H; Wu, J; Zhang, Y; Zhao, S | 1 |
| Cuenod, M; das Neves Duarte, JM; Do, KQ; Gholam-Razaee, MM; Gruetter, R; Kulak, A | 1 |
| Artiukhina, ZE; Ekimova, IV; Guzhova, IV; Pastukhov, IuF; Romanova, IV | 1 |
| Khanna, AK; Mehra, MR; Xu, J | 1 |
| Büchler, MW; Gebhard, MM; Hackert, T; Hartwig, W; Kaiser, H; Klar, E; Schmidt, J; Werner, J | 1 |
| Atli, Y; Bulbuloglu, E; Coskuner, I; Deniz, C; Dogan, Z; Kantarçeken, B; Kilinc, M; Oksuz, H; Senoglu, N; Yildiz, H; Yuzbasioglu, MF | 1 |
| Graham, LM; Miyazaki, K; Rosenbaum, MA | 1 |
| Cai, YB; Gong, KZ; Li, Z; Liu, N | 1 |
| Benjamim, CF; Caetano, M; Lima Trajano, ET; Magalhães, CB; Porto, LC; Ribeiro, ML; Santos Silva, MA; Santos, JC; Sternberg, C; Valença, SS; Zin, WA | 1 |
| Castro Junior, MA; Castro, AP; Facin, E; Fagundes, DJ; Lauz, S; Simões, Mde J | 1 |
| Álvares-da-Silva, MR; Alvares-Dasilva, MR; Camacho, VR; Cerski, CT; de Fraga, RS; de Oliveira, JR; Fraga, RS; Oliveira, JR | 1 |
| Barrière, DA; Busserolles, J; Chanteranne, D; Chapuis, L; Chauvin, MA; Dubray, C; Morio, B; Rieusset, J; Salles, J | 1 |
| Chen, K; Cheng, W; Choi, CH; Du, X; Floyd, RA; Hu, N; Kopke, RD; Li, W; Stewart, C | 1 |
| Chen, SH; Gean, PW; Hsiao, YH; Kuo, JR | 1 |
| Favari, L; Galicia-Moreno, M; Muriel, P | 1 |
| Andrade, L; Campos, R; Canale, D; de Bragança, AC; Lopes, FD; Olivo, C; Seguro, AC; Shimizu, MH; Volpini, RA | 1 |
| Du, X; Ewert, DL; Floyd, R; Kopke, R; Li, W; Lu, J | 1 |
| Chian, CF; Chiang, CH; Chuang, CH; Liu, SL; Ryu, JH; Zhang, H | 1 |
| Delavari, F; Kadkhodaee, M; Mikaeili, S; Ostad, SN; Seifi, B; Shams, S | 1 |
| Asl, AH; Jahanshahi, A; Khansari, M; Sotoudeh, A; Takhtfooladi, HA; Takhtfooladi, MA | 1 |
| Adesanoye, OA; Ekor, M; Farombi, EO | 1 |
| Arbogast, S; Brooks, SV; Dowling, JJ; Ferreiro, A; Hur, J; Kuwada, JY; Lunardi, J; Marty, I; McEvoy, A; Nelson, DD; Waugh, T | 1 |
| Buckley, B; DiCicco-Bloom, E; Falluel-Morel, A; Lin, L; McCandlish, E; Sokolowski, K | 1 |
| Andiran, F; Haltas, H; Hirfanoglu, IM; Kosus, A; Tatli, MM; Tayman, C; Tonbul, A; Uysal, S | 1 |
| Comim, CM; Dominguini, D; Ferreira, GC; Jeremias, IC; Mina, F; Morais, MO; Pescador, B; Quevedo, J; Scaini, G; Schuck, PF; Streck, EL; Teodorak, BP | 1 |
| Gu, L; Sun, L; Wang, S; Yang, H; Yuan, J; Zhang, H; Zhu, J | 1 |
| Collía, F; De Dios, I; Manso, MA; Ramudo, L; Yubero, S | 1 |
| Hintermann, S; Jankovic, J; Le, W; Li, X; Tuo, H; Xie, WJ; Zhang, Z | 1 |
| Carlsson, K; Celsi, G; Gong, X; Norgren, S | 1 |
| Ljubisavljevic, S; Milojkovic, M; Pavlovic, D; Sokolovic, D; Stevanovic, I; Stojanovic, I; Vojinovic, S | 1 |
| Miller, G | 1 |
| Devi, PU; Manocha, A; Saraogi, P; Vohora, D | 1 |
| Aydogan, T; Erdogan, D; Eren, MA; Iraz, M; Koksal, M; Kurcer, Z; Tas, M; Ulas, T | 1 |
| Ando, R; Fukami, K; Iwatani, R; Kaida, Y; Nakayama, Y; Okuda, S; Ueda, S; Yamagishi, S | 1 |
| Costa, VM; de Araújo, SB; de Azevedo Albuquerque, MC; de Lima Aires, A; de Pontes Filho, NT; Malagueño, E; Schirato, GV; Silva, RA; Souza, VM | 1 |
| Böhme, A; Bönisch, U; Kohajda, T; Lehmann, I; Mögel, I; Polte, T; Schütze, N; Simon, JC; von Bergen, M | 1 |
| Filip, M; Krzyżanowska, W; Miszkiel, J; Niedzielska, E; Ogórka, A; Pomierny, B; Pomierny-Chamioło, L; Smaga, I | 1 |
| Di Maio, R; Greenamyre, JT; Hu, X; Mastroberardino, PG; Montero, LM | 1 |
| Calkovska, A; Drgova, A; Kopincova, J; Mokra, D; Pullmann, R | 1 |
| Chargui, A; Cougnon, M; Duranton, C; Melis, N; Mograbi, B; Rubera, I; Tauc, M | 1 |
| Hawkins-Salsbury, JA; Qin, EY; Reddy, AS; Sands, MS; Vogler, CA | 1 |
| Ferreira, SG; Koike, MK; Montero, EF; Oliveira Filho, LD; Saad, KR; Saad, PF | 1 |
| Borman, H; Deniz, M; Haberal, M; Seyhan, T | 1 |
| Jiang, R; Lu, H; Peng, X; Wan, J; Xie, J; Zhang, L | 1 |
| Brito, JM; Dantas Filho, L; Dolhnikoff, M; Koike, MK; Montero, EF; Saad, KR; Saad, PF; Zanoni, FL | 1 |
| Abbasi, H; Aran, S; Ghaffari, A; Keshavarz, A; Seifirad, S; Taslimi, S | 1 |
| Benjamin, IJ; Brewer, AC; Murray, TV; Mustafi, SB; Rajasekaran, NS | 1 |
| Uomo, G | 1 |
| Canpolat, FE; Dilmen, U; Erdeve, O; Ozdemir, R; Sarı, FN; Unverdi, HG; Uysal, B; Yurttutan, S | 1 |
| Dou, X; Gu, D; Li, S; Shen, C; Song, Z; Wang, Z; Yao, T | 1 |
| Enaida, H; Hisatomi, T; Ikeda, Y; Ishibashi, T; Ishikawa, K; Murakami, Y; Notomi, S; Yoshida, N | 1 |
| Chen, L; Li, J; Li, S; Li, W; Su, X; Yan, G; Yang, X | 1 |
| Carbonel, AA; Montero, EF; Silva, SM; Simões, MJ; Taha, MO | 1 |
| Aslam, S; Darouiche, R; Ghannoum, M; Jenne, K; Mehta, R; Reed, S | 1 |
| Bogo, MR; Comim, CM; Ferreira, GC; Gelain, DP; Moreira, JC; Oliveira, GM; Pasquali, MA; Quevedo, J; Scaini, G; Schuck, PF; Streck, EL | 1 |
| Chen, L; Liang, S; Wang, R; Yue, H | 1 |
| Geng, C; Gong, D; Ishikawa, N; Jiang, L; Kajima, K; Li, L; Zhong, L | 1 |
| El-Maraghy, SA; Hamdy, MA; Kortam, MA | 1 |
| Baker, DA; Choi, S; Kong, L; Lutgen, V; Qualmann, K; Resch, J | 1 |
| Gao, L; Guo, NN; Kang, JR; Li, F; Lu, JY; Sun, JZ; Wang, HW; Yang, W; Zhang, W | 1 |
| Chen, CW; Cummins, JH; Gao, X; Huard, J; Li, H; Lu, A; Tang, Y; Tebbets, JC; Usas, A; Wang, B | 1 |
| Andreu, AL; Bianchi, P; Ferrer, I; Fourcade, S; Galino, J; López-Erauskin, J; Muñoz-Pinedo, C; Pujol, A | 1 |
| Anogianakis, G; Guibas, GV; Meditskou, S; Priftis, KN; Spandou, E; Vyzantiadis, TA | 1 |
| Arni, S; Buschmann, J; Erne, BV; Inci, I; Jungraithmayr, W; Weder, W | 1 |
| De la Fuente, M; Guayerbas, N; Puerto, M; Víctor, V | 1 |
| De La Fuente, M; Ferrández, MD; Guayerbas, N; Puerto, M | 1 |
| Adams, J; Ardeshirpour, F; Baldwin, AS; Bellinger, DA; Elliott, PJ; Fischer, TH; McCain, A; Merricks, E; Nichols, TC; Pien, C; Pye, J | 1 |
| Fu, Z; He, B; Liu, L; Liu, Z; Wu, J; Yang, Z | 1 |
| Barrett, JC; French, JE; Kari, FW; Martin, KR; Saulnier, MJ | 1 |
| Arreola, JL; Barrios, R; Cisneros-Lira, J; Gaxiola, M; Kala, SV; Lieberman, MW; Pardo, A; Ramírez, R; Ruiz, V; Selman, M | 1 |
| Haddad, IY | 1 |
| Bhalla, KS; Folz, RJ | 1 |
| Broseta, L; Fernández-Fúnez, A; Polo, FJ; Valer, J; Zafrilla, L | 1 |
| Asayama, K; Dobashi, K; Orak, JK; Singh, AK; Singh, I | 1 |
| Giri, S; Mehta, A; Orak, JK; Sekhon, CP; Singh, AK | 1 |
| Branton, RL; Brundin, P; Clarke, DJ; Karlsson, J; Love, RM | 1 |
| Anttila, A; Jusufovic, J; Kauppinen, H; Koivusalo, A; Lindahl, H; Rautelin, H; Rintala, R | 1 |
| Banks, WA; Butterfield, DA; Dogrukol-Ak, D; Drake, J; Eyerman, E; Farr, SA; Morley, JE; Poon, HF | 1 |
| Miller, JM; Ohinata, Y; Schacht, J | 1 |
| Blesa, S; Closa, D; Cortijo, J; Estrela, JM; Mata, M; Morcillo, EJ; Santangelo, F; Serrano, A; Suchankova, J | 1 |
| Blesa, S; Bulbena, O; Closa, D; Cortijo, J; Estrela, JM; Martinez-Losa, M; Morcillo, EJ; Prats, N; Serrano-Mollar, A | 1 |
| Gwag, BJ; Han, BS; Noh, JS; Oh, YJ | 1 |
| Avlan, D; Cinel, I; Cinel, L; Dikmengil, M; Koksel, O; Okcu, H; Oral, U; Ozdulger, A; Unlu, A | 1 |
| Boehncke, WH; Elliott, PJ; Zollner, TM | 1 |
| Ruh, J; Schmidt, E; Vogel, F | 1 |
| Bozkurt, AK; Cangel, U; Koksal, C; Konukoglu, D; Musellim, B; Sayin, AG; Ustundag, N | 1 |
| Behar, TN; Colton, CA | 1 |
| Kastenbauer, S; Klein, M; Koedel, U; Pfister, HW | 1 |
| Delvin, E; Lambert, M; Levy, E; Seidman, E; Ziv, E; Zoltowska, M | 1 |
| De Dios, I; de la Mano, AM; Manso, MA; Orfao, A; Sevillano, S | 1 |
| Balansky, RM; Camoirano, A; Cartiglia, C; De Flora, S; Izzotti, A; Longobardi, M; Tampa, E | 1 |
| Allen, SJ; Cox, CS; Fischer, UM; Laine, GA; Mehlhorn, U; Stewart, RH | 1 |
| Kraemer, DF; Muldoon, LL; Neuwelt, EA; Pagel, MA; Peterson, DR | 1 |
| Bouchier-Hayes, D; Condron, C; Kearns, S; Murray, P; Power, C; Street, J; Thornes, B; Timlin, M; Toomey, D | 1 |
| Cheema, SS; Lopes, EC; Turner, BJ | 1 |
| Adams, J; Berti, R; Dave, JR; Elliot, PJ; Tortella, FC; Williams, AJ | 1 |
| Agarwal, A; Claffey, KP; Klueh, U; Muñoz-Nájar, U; Shih, SC | 1 |
| Gilg, AG; Giri, S; Jatana, M; Khan, M; Sekhon, B; Sekhon, C; Singh, AK; Singh, I | 1 |
| Atlas, D; Barhum, Y; Benhar, M; Gilgun-Sherki, Y; Grinberg, L; Melamed, E; Offen, D; Reich, R | 1 |
| Baek, SY; Chung, BS; Kang, CD; Kim, JY; Kim, SD; Kim, SH; Park, KH; Park, SW | 1 |
| Bueno, AS; Montero, EF; Poli de Figueiredo, LF; Portella, AO; Rodrigues, FG; Thurow, AA | 1 |
| Horta, MF; Ramalho-Pinto, FJ; Silva-Jardim, I | 1 |
| Deray, G | 1 |
| Cai, BQ; Gu, L; Guo, ZJ; Xu, L; Xu, XX; Zhang, H; Zhu, YJ | 1 |
| Chavin, K; Lin, A; Orak, J; Sekhon, B; Sekhon, C; Singh, A; Singh, I; Smith, A | 1 |
| Barbosa, E; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I | 1 |
| Liu, S; Yu, SY | 1 |
| Aban, M; Apa, DD; Dilek, S; Kaplanoğlu, M; Oz, U; Pata, O; Tok, E; Yazici, G | 1 |
| Irie, J; Oikawa, Y; Saruta, T; Shigihara, T; Shimada, A | 1 |
| Atik, U; Cinel, I; Cinel, L; Ercan, B; Ercil, M; Kanik, A; Koksel, O; Ozdulger, A; Tamer, L | 1 |
| Averbukh, M; Averbukh, Z; Berman, S; Dishy, V; Efrati, S; Feldman, L; Golik, A; Kachko, L; Weissgarten, J | 1 |
| Chang, KW; Chinosornvatana, N; Choe, WT | 1 |
| Atienza, MP; Broseta Viana, L; Fernández-Fúnez, A; Polo-Romero, FJ; Sánchez Gascón, F | 1 |
| Chen, XH; He, LX; Li, HP; Li, ZZ; Pan, J; Qu, JM; Xu, JF; Zhang, J | 1 |
| Hazell, AS; Yi, JH | 1 |
| Bates, CM; Lin, F | 1 |
| Cai, G; Dai, Y; Li, Q; Nie, X; Zhang, J | 1 |
| Bosma, PJ; Buskens, CJ; Marsman, WA; Van Lanschot, JJ; Wesseling, JG | 1 |
| Ahn, MT; Kalbe, L; Kruhoffer, M; Leunda, A; Meulemans, C; Nerup, J; Orntoft, T; Remacle, C; Reusens, B; Sparre, T | 1 |
| Armutcu, F; Iraz, M; Kotuk, M; Kuku, I; Ozen, S; Ulu, R; Yildirim, Z | 1 |
| Bielefeld, E; Coleman, JK; Henderson, D; Jackson, R; Kopke, R; Liu, J; Zheng, J | 1 |
| Graves, M; Ortiz, D; Rogers, E; Shea, TB; Tchantchou, F | 1 |
| Hardman, J; McMahon, R; Redmond, HP; Schofield, D; Shields, C; Siriwardena, AK | 1 |
| Barbosa, E; Chang, EY; Paintlia, MK; Singh, A; Singh, I | 1 |
| Andrade, L; Coimbra, TM; de Araujo, M; Rodrigues, AC; Seguro, AC | 1 |
| Dudhgaonkar, SP; Jadhav, SH; Kataria, M; Kumar, D; Naik, AK; Prakash, VR; Tandan, SK | 1 |
| Akca, T; Aydin, S; Bilgin, O; Caglikulekci, M; Canbaz, H; Colak, T; Kanik, A; Tamer, L; Tataroglu, C | 1 |
| Becker, TC; Cao, W; Collins, QF; Collins, S; Daniel, KW; Floering, L; Lupo, EG; Robidoux, J; Xiong, Y | 1 |
| Crespo, MJ; Escobales, N | 1 |
| Barreiro, E; Gáldiz, JB; Gea, J; Hussain, SN; Sánchez, D | 1 |
| Adamsky, K; Amariglio, N; Breda, L; Cabantchik, ZI; Rachmilewitz, EA; Rechavi, G; Rivella, S; Weizer-Stern, O | 1 |
| Hazell, AS; Kennedy, G; Norenberg, MD; Normandin, L; Yi, JH | 1 |
| Basu, S; Guron, G; Haraldsson, B; Marcussen, N; Nilsson, U; Nitescu, N; Ricksten, SE | 1 |
| Andrades, M; da Cunha, AA; Dal-Pizzol, F; Echer, IC; Lucchiari, N; Menna-Barreto, S; Moreira, JC; Reinke, A; Ritter, C; Rocha, J; Streck, EL | 1 |
| Cross, CE; Halliwell, B; van Asbeck, BS | 1 |
| Hazell, AS; Hoover, R; McIntosh, TK; Yi, JH | 1 |
| Kuo, YM; Wu, Z; Yang, Y; Zhou, B | 1 |
| Akan, P; Camsari, T; Celik, A; Ormen, M; Sarioglu, S; Yenicerioglu, Y; Yilmaz, O | 1 |
| Griebenow, M; Kroppenstedt, SN; Stover, JF; Thomale, UW; Unterberg, AW | 1 |
| Bilodeau, M; Zwingmann, C | 1 |
| de Macedo Possamai, V; Guo, Z; Hu, L; McKenzie, KU; Miao, Y; Mondo, CK; Schyvens, CG; Whitworth, JA; Zhang, Y | 1 |
| Abdalla, DS; Alves, VA; Carrilho, FJ; de Lima, VM; de Oliveira, CP; de Oliveira, MG; Laurindo, FR; Lopasso, FP; Simplicio, FI; Yuahasi, K | 1 |
| Ancha, H; Harty, RF; Lightfoot, S; Siddiqui, A; Stewart, CA; Tedesco, D | 1 |
| Pillai, KK; Uma Devi, P; Vohora, D | 1 |
| Meng, Q; Shen, C; Wu, YT; Yin, J; Yu, JP | 1 |
| Al-Humadi, NH; Hu, S; Ma, JK; Yin, XJ; Zhao, H | 1 |
| Achat-Mendes, C; Anderson, KL; Itzhak, Y | 1 |
| Bates, KA; Harvey, AR; Martins, RN | 1 |
| Assimakopoulos, SF; Chroni, E; Georgiou, C; Karageorgos, N; Konstantinou, D; Patsoukis, N | 1 |
| Esme, H; Fidan, F; Köken, T; Sahin, O; Sezer, M; Unlü, M | 1 |
| Bozkurt, AK; Cortelekoglu, T; Koksal, C; Konukoglu, D; Musellim, B; Sayin, AG; Sirin, G; Ustundag, N | 1 |
| Alkan, A; Alsancak, G; Cerçi, C; Ergin, C; Eroğlu, E; Eroğlu, F | 1 |
| Demura, Y; Scerbavicius, R; Taraseviciene-Stewart, L; Tuder, RM; Voelkel, NF | 1 |
| Alvarez, M; Culebras, JM; González-Gallego, J; San-Miguel, B; Tuñón, MJ | 1 |
| Li, HC; Tian, H; Zhang, GY; Zhang, QG | 1 |
| Dwyer, TM; Hughson, MD; Jordan, S; Manning, RD; Rose, RA; Tian, N | 1 |
| De Cock, K; De Muynck, M; Rimbaut, S; Van Maele, G; Vanden Bossche, LC; Vanderstraeten, GG; Vertriest, S; Wojtowicz, I | 1 |
| Camara, NO; Di Giorno, C; Franco, MF; Galante, NZ; Heinke, T; Pacheco-Silva, A; Pinheiro, HS | 1 |
| Kamboj, A; Sandhir, R | 1 |
| Aladag, M; Ara, C; Ciralik, H; Demirel, U; Firat, S; Harputluoglu, MM; Hilmioglu, F; Karincaoglu, M; Temel, I | 1 |
| Dong, G; Jing, H; Luo, L; Shao, H; Yin, R; Zhu, J | 1 |
| Biswas, SK; de Faria, JB | 1 |
| Clouzeau-Girard, H; Combe, C; Desmoulière, A; Guyot, C; Moronvalle-Halley, V | 1 |
| Biberoglu, N; Bozbas, A; Eren, F; Gedik, N; Guzel, S; Sahan, E; Tahan, G; Tahan, V; Tarcin, O; Tozun, N; Yucel, O | 1 |
| Celik, S; Erdogan, S; Gorur, S; Hakverdi, S; Ocak, S | 1 |
| Klaikeaw, N; Kulaputana, O; Patumraj, S; Samuhasaneeto, S; Thong-Ngam, D | 1 |
| Bardini, KC; Benetton, CA; Cardoso, VH; Dal-Pizzol, F; Damiani, CR; Di Giunta, G; Pinho, RA; Stoffel, C; Streck, EL | 1 |
| De Dios, I; Manso, MA; Ramudo, L; Vicente, S; Yubero, S | 1 |
| Betten, DP; Clark, RF; Favata, M; Hernandez, M; Richardson, WH; Riffenburgh, RH; Tanen, DA; Tong, TC | 1 |
| Allen, DG; Williams, IA | 1 |
| Moss, NC; Selzman, CH; Stansfield, WE; Tang, R; Willis, MS | 1 |
| Aydin, A; Bolcal, C; Demirkilic, U; Doganci, S; Kuralay, E; Oz, BS; Ozal, E; Sargin, M; Sayal, A; Tatar, H; Yildirim, V | 1 |
| Bijarnia, RK; Kaur, T; Singla, SK; Tandon, C | 1 |
| De Lisle, RC; Jansson, K; Roach, E | 1 |
| Geisen, P; Hartnett, ME; Saito, Y; Uppal, A | 1 |
| Dong, G; Feng, X; Huang, H; Jing, H; Li, D; Sheng, Y; Wang, C; Yin, R; Zhu, J | 1 |
| Jin, X; Tian, Y; Wang, CY; Wu, HS; Zhang, JH | 1 |
| Geudens, N; Lerut, TE; Neyrinck, AP; Rega, FR; Van Raemdonck, DE; Vanaudenaerde, BM; Verleden, GM; Wuyts, WA | 1 |
| Amer, J; Fibach, E; Reich, S; Shapira, MY; Slavin, S; Weiss, L | 1 |
| Arsenault, L; Banquerigo, ML; Boyle, DL; Brahn, E; Cheng, TP; Cruz, TF; Firestein, GS; Oliver, SJ | 1 |
| Adamy, C; Andrieu-abadie, N; Berdeaux, A; Candiani, G; Caramelle, P; Damy, T; Defer, N; Hittinger, L; Khouzami, L; Kirsch, M; Le Corvoisier, P; Levade, T; Mulder, P; Pavoine, C; Pecker, F; Perier, M; Souktani, R; Thuillez, C | 1 |
| Kalivas, PW; Zhou, W | 1 |
| Baker, DA; Haroutunian, V; Kristiansen, LV; Madayag, A; Meador-Woodruff, JH; Raju, I | 1 |
| Barichello, T; Constantino, L; Dal-Pizzol, F; Machado, RA; Martins, MR; Petronilho, F; Quevedo, J; Réus, GZ; Ritter, C; Valvassori, SS | 1 |
| Li, YH; Liu, KX; Tian, XF; Wang, YZ; Wang, ZZ; Yao, JH; Yuan, JC; Zhang, XS; Zhou, Q | 1 |
| Fela, DA; Gonzalez, AV; Gordon, JS; Perez, E; Rouzard, K; Sarngadharan, G; Stock, JB; Stock, MB; Wolanin, PM | 1 |
| Barnes, K; Biswal, S; Crow, MT; Dodd-O, JM; Grigoryev, DN; Hassoun, PM; Kensler, TW; Mitzner, W; Papaiahgari, S; Reddy, NM; Reddy, SP; Reddy, SR; Tuder, RM; Yamamoto, M; Yerrapureddy, A | 1 |
| Fujioka, D; Kawabata, K; Kitta, Y; Kobayashi, T; Kodama, Y; Kugiyama, K; Nakamura, T; Obata, JE; Saito, Y; Takano, H; Yano, T | 1 |
| Kilic, MA; Kilinc, M; Okur, E; Tolun, FI; Yildirim, I | 1 |
| Dehpour, AR; Faghihi, SH; Kiumehr, S; Nourbakhsh, B; Payabvash, S; Salmasi, AH; Tavangar, SM | 1 |
| Lu, JW; Wang, H; Wei, W; Xu, DX; Zhang, C; Zhao, L | 1 |
| Macarthur, H; Westfall, TC; Wilken, GH | 1 |
| Alipour, M; Omri, A; Smith, MG; Suntres, ZE | 1 |
| Jia, YT; Liu, WJ; Lv, KY; Ma, B; Tang, HT; Wang, Y; Wei, D; Wei, W; Xia, ZF; Xu, Y | 1 |
| Cagiano, R; Cazzato, A; Colantuono, G; D'Agostino, D; Di Venosa, N; Federici, A; Fiore, T; Rastaldo, R; Tiravanti, EA | 1 |
| Adachi, Y; Sakurai, H; Yoshikawa, Y | 1 |
| Elmes, MJ; Gardner, DS; Langley-Evans, SC; McMullen, S | 1 |
| Aktoz, T; Atakan, IH; Aydoğdu, N; Inci, O; Kaplan, M; Ozpuyan, F; Seren, G; Tokuç, B | 1 |
| Aoyama, K; Matsumura, N; Nakaki, T; Watabe, M | 1 |
| Geudens, N; Lerut, T; Neyrinck, AP; Timmermans, L; Van De Wauwer, C; Van Raemdonck, DE; Vanaudenaerde, BM; Vanhooren, HM; Verbeken, E; Verleden, GM | 1 |
| Casabianca, A; Chiarantini, L; Cinatl, J; Clayette, P; Fraternale, A; Magnani, M; Oiry, J; Orlandi, C; Paoletti, MF; Schiavano, GF; Vogel, JU | 1 |
| Bartos, V; Brozmanova, M; Javorka, M; Masar, J; Plank, L; Plevkova, J; Tatar, M | 1 |
| Molnár, Z | 1 |
| Chae, HZ; Hwang, JY; Jin, BK; Lee, TH; Lee, YM; Oh, TH; Oh, YJ; Park, B; Park, SH; Park, YJ; Shin, DI | 1 |
| Allen, DG; Gervasio, OL; Pham, C; Whitehead, NP | 1 |
| Aleksa, K; Chen, N; Koren, G; Rieder, M; Woodland, C | 1 |
| Powell, SR | 1 |
| Altaner, S; Aydogdu, N; Erbas, H; Inan, M; Oz Puyan, F; Usta, U | 1 |
| Reggiani, C | 1 |
| Fujigaki, Y; Hishida, A; Luo, J; Sun, Y; Tsuji, T; Yasuda, H | 1 |
| Abe, M; Ichimaru, S; Takiguchi, Y; Tsuchiya, K; Wada, K | 1 |
| Hales, CA; Jafari, B; Quinn, DA; Syrkina, O | 1 |
| Ballard, C; Iravani, MM; Jenner, P; MacInnes, N; Perry, E; Perry, R; Piggott, M | 1 |
| Bigam, DL; Cheung, PY; Lee, TF; Tymafichuk, CN | 1 |
| Chen, S; Du, Y; Huang, K; Le, W; Li, X; Yang, D; Zhang, X | 1 |
| Hou, MC; Huang, YT; Lee, FY; Lee, KC; Lee, SD; Lin, HC; Wang, YW; Yang, YY | 1 |
| Hallberg, A; Särnstrand, B; Sjödin, K; Tunek, A | 1 |
| Bakker, J; Depierreux, M; van Asbeck, S; Vincent, JL; Zhang, H | 1 |
| Bernard, GR; Christman, BW | 1 |
| Bernard, GR; Morris, PE | 1 |
| Beehler, CJ; Hybertson, BM; Leff, JA; Repine, JE; Shanley, PF; Wilke, CP | 1 |
| Echtenacher, B; Faggioni, R; Gatti, S; Ghezzi, P | 1 |
| Kelly, FJ; Langley, SC | 1 |
| Archibald, V; Cameron, NE; Cotter, MA; Keegan, A | 1 |
| Blackwell, TR; Blackwell, TS; Christman, BW; Christman, JW; Holden, EP | 1 |
| Albini, A; D'Agostini, F; De Flora, S; Giunciuglio, D; Masiello, L | 1 |
| Benson, PF; Doctrow, SR; Fink, MP; Gonzalez, PK; Malfroy, B; Menconi, MJ; Zhuang, J | 1 |
| Cahill-Morasco, R; Goldfrank, LR; Hoffman, RS; Meggs, WJ; Shih, RD | 1 |
| Davreux, CJ; McGilvray, ID; Nathens, AB; Rotstein, OD; Shek, PN; Soric, I; Suntres, ZE; Watson, RW | 1 |
| Chirila, TV; Clayton, AB; Constable, IJ; Crawford, GJ; Fitton, JH; Hicks, CR; Ziegelaar, BW | 1 |
| Barfuss, DW; Zalups, RK | 1 |
| Fukumoto, T; Moriuchi, H; Yuizono, T; Zaha, M | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S | 1 |
| Caputi, AP; Costantino, G; Cuzzocrea, S; Mazzon, E | 1 |
| Akbay, A; Bozdayi, M; Bozkaya, H; Cinar, K; Eranil, S; Uzunalimoğlu, O; Yurdaydin, C | 1 |
| De la Fuente, M; Guaza, C; Hernanz, A; Molina-Holgado, F | 1 |
| De la Fuente, M; Del Río, M; Garrote, D; Guayerbas, N; Víctor, VM | 1 |
| De la Fuente, M; Victor, VM | 1 |
| Auer, M; Leib, SL; Leppert, D; Pfister, LA; Täuber, MG | 1 |
| Adams, J; Elliott, PJ; Phillips, JB; Tortella, FC; Williams, AJ | 1 |
| Andreassen, OA; Beal, MF; Bush, AI; Dedeoglu, A; Klivenyi, P | 1 |
| Bicknell, R; Cranston, D; Fuggle, S; Fujiyama, C; Harris, AL; Jones, A | 1 |
| Alam, J; Das, DK; Ho, YS; Maulik, N; Yoshida, T | 1 |
| Caputi, AP; Centorrino, T; Ciccolo, A; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Bauer, I; Bauer, M; Pannen, BH; Paxian, M; Rensing, H; Rickauer, A; Schmeck, J; Schönhofen, S | 1 |
| Arregui, B; Conesa, EL; Fenoy, FJ; López, B; Nadal, JC; Salom, MG; Valero, F | 1 |
| Banic, S; Bifrare, YD; Christen, S; Leib, SL; Lykkesfeldt, J; Schaper, M; Siegenthaler, C; Täuber, MG | 1 |
| Hayashi, K; Kaminogo, M; Kitagawa, N; Kitange, G; Shibata, S; Takahata, H | 1 |
| Avila, J; Hen, R; Hernández, F; Lucas, JJ; Martín-Aparicio, E; Yamamoto, A | 1 |
| Elliott, PJ; Ross, JS | 1 |
| Adams, J; Chopp, M; Elliott, PJ; Lu, M; Zhang, L; Zhang, RL; Zhang, ZG | 1 |
| Blesa, S; Cortijo, J; Martinez-Losa, M; Mata, M; Morcillo, EJ; Santangelo, F; Seda, E | 1 |
| Boehncke, WH; Elliott, PJ; Kaufmann, R; Pien, C; Podda, M; Zollner, TM | 1 |
| Gare, M; Kehl, F; Kersten, JR; Mraovic, B; Pagel, PS; Warltier, DC | 1 |
| Ho, KL; Liao, J; Seril, DN; Yang, CS; Yang, GY | 1 |
| Ashton, PW; Brunetto, AL; Kalakun, L; Leite, VL; Marques, AR; Sander, EB; Sanvitto, G; Schwartsmann, G; Vinholes, J; Wissmann, G | 1 |
| Eadie, PA; Knight, KR; Kuwata, N; Lepore, DA; MacPhadyen, K; O'Brien, BM | 1 |
| Alberola, A; Gil, F; Morcillo, EJ; Such, L; Zaragoza, R | 1 |
| Livingston, GL; Schild, JA | 1 |
| Godfrey, RW; Jeffery, PK; Majumdar, S; Rogers, DF | 1 |
| Alp, MH; Hickman, R | 1 |
| Kline, I | 1 |
| Christensen, G; Evans, RM; Mc Crary, JA | 1 |
20 review(s) available for acetylcysteine and Disease Models, Animal
| Article | Year |
|---|---|
The Role of N-Acetylcysteine in Platelet Aggregation and Reperfusion Injury in Recent Years.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Reperfusion Injury; Species Specificity | 2017 |
Preconditioning against renal ischaemia reperfusion injury: the failure to translate to the clinic.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Chelating Agents; Disease Models, Animal; Diuretics, Osmotic; Endpoint Determination; Free Radical Scavengers; Humans; Hypoxia-Inducible Factor 1; Ischemic Preconditioning; Kidney; Mannitol; Oligopeptides; Reperfusion Injury; Reproducibility of Results; Translational Research, Biomedical | 2019 |
Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation.
Topics: Acetylcysteine; Age of Onset; Animals; Basal Ganglia; Behavior, Addictive; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Comorbidity; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Epigenomics; Free Radical Scavengers; Humans; Recurrence; Stress, Psychological | 2013 |
The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review.
Topics: Acetylcysteine; Animals; Bronchiolitis Obliterans; Chemical Warfare Agents; Disease Models, Animal; Humans; Lung; Mustard Gas; Oxidative Stress; Randomized Controlled Trials as Topic | 2014 |
Complementary and alternative treatments for autism part 1: evidence-supported treatments.
Topics: Acetylcysteine; Animals; Antipsychotic Agents; Aripiprazole; Autistic Disorder; Complementary Therapies; Disease Models, Animal; Evidence-Based Medicine; Free Radical Scavengers; Gastrointestinal Tract; Humans; Inflammation; Mice; Oxidative Stress; Randomized Controlled Trials as Topic; Risperidone; United States; United States Food and Drug Administration; Vitamin B 12 | 2015 |
Bridging Translation by Improving Preclinical Study Design in AKI.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Erythropoietin; Free Radical Scavengers; Humans; Research Design; Sodium Bicarbonate; Translational Research, Biomedical | 2015 |
The effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.
Topics: Acetylcysteine; Amino Acids, Sulfur; Animals; Betaine; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Genotype; Homocystinuria; Humans; Metabolic Networks and Pathways; Methionine; Mice; Mice, Knockout; Mutation; Phenotype | 2016 |
[Effectiveness of N-acetylcysteine in the treatment of schizophrenia].
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Glutathione; Humans; Microglia; Neuroprotective Agents; Oxidative Stress; Schizophrenia | 2016 |
Insights into the Pathogenesis and Treatment of Krabbe Disease.
Topics: Acetylcysteine; Animals; Antimetabolites; Bone Marrow Transplantation; Central Nervous System; Cycloserine; Disease Models, Animal; Enzyme Replacement Therapy; Free Radical Scavengers; Galactosylceramidase; Genetic Therapy; Hematopoietic Stem Cell Transplantation; Humans; Leukodystrophy, Globoid Cell; Phenotype; Phosphodiesterase Inhibitors; Pyridines | 2016 |
Experimental and clinical evidence for modification of hepatic ischaemia-reperfusion injury by N-acetylcysteine during major liver surgery.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Evidence-Based Medicine; Hepatectomy; Humans; Liver; Liver Transplantation; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Treatment Outcome | 2011 |
Reductive stress linked to small HSPs, G6PD, and Nrf2 pathways in heart disease.
Topics: Acetylcysteine; alpha-Crystallin B Chain; Animals; Antioxidants; Catalase; Disease Models, Animal; Early Diagnosis; Glucosephosphate Dehydrogenase; Glutathione; Heart Diseases; Heat-Shock Proteins; Humans; Mice; Models, Cardiovascular; Molecular Chaperones; Neoplasm Proteins; NF-E2-Related Factor 2; Peroxidases; Precision Medicine; Reactive Nitrogen Species; Reactive Oxygen Species; Recombinant Fusion Proteins; Superoxide Dismutase; Thioredoxins | 2013 |
Proteasome inhibition: a new anti-inflammatory strategy.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Asthma; Boronic Acids; Bortezomib; Clinical Trials as Topic; Cysteine Endopeptidases; Disease Models, Animal; Humans; Inflammation; Lysine; Models, Biological; Models, Chemical; Multienzyme Complexes; Multiple Sclerosis; Neoplasms; NF-kappa B; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Psoriasis; Pyrazines; Reperfusion Injury | 2003 |
[Value of N-acetylcysteine to prevent nephrotoxicity from iodinated contrast agents].
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Contrast Media; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Humans; Iodine Radioisotopes; Risk Factors; Treatment Outcome | 2004 |
Future strategies in the treatment of acute renal failure: growth factors, stem cells, and other novel therapies.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Disease Models, Animal; Heme Oxygenase-1; Hepatocyte Growth Factor; Humans; Nitric Oxide Synthase; PPAR alpha; Pyrimidines; Stem Cell Transplantation | 2005 |
Role of iron in inducing oxidative stress in thalassemia: Can it be prevented by inhibition of absorption and by antioxidants?
Topics: Acetylcysteine; Animals; Antimicrobial Cationic Peptides; Antioxidants; Bone Marrow; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Drug Therapy, Combination; Erythrocytes; Gene Expression Regulation; Genetic Therapy; Hepcidins; Humans; Intestinal Absorption; Iron; Iron Chelating Agents; Iron, Dietary; Liver Neoplasms; Mice; Oxidants; Oxidative Stress; Thalassemia; Vitamin E | 2005 |
Antilipid mediator and antioxidant therapy in adult respiratory distress syndrome.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Epoprostenol; Humans; Inflammation; Intensive Care Units; Leukotrienes; Lipid Peroxidation; Middle Aged; Platelet Activating Factor; Respiratory Distress Syndrome; Thromboxanes; Treatment Failure | 1993 |
Significance of glutathione in lung disease and implications for therapy.
Topics: Acetylcysteine; Animals; Cysteine; Disease Models, Animal; Glutathione; Humans; Inflammation; Lung Diseases; NF-kappa B | 1994 |
Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury.
Topics: Acetylcysteine; Adult; Animals; Catalase; Disease Models, Animal; Endotoxins; Ethylenediamines; Free Radical Scavengers; Humans; Lipopolysaccharides; Lung; Lung Injury; Organometallic Compounds; Oxidative Stress; Reactive Oxygen Species; Respiratory Distress Syndrome; Superoxide Dismutase; Swine; Thiourea | 1996 |
The proteasome: a new target for novel drug therapies.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Carcinoma, Lewis Lung; Clinical Trials, Phase I as Topic; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Humans; Multienzyme Complexes; Neoplasms; Proteasome Endopeptidase Complex; Pyrazines | 2001 |
Collagenase inhibitors: rationale for their use in treating corneal ulceration.
Topics: Acetylcysteine; alpha 1-Antitrypsin; alpha-Macroglobulins; Animals; Calcium; Corneal Ulcer; Cyclic AMP; Cysteine; Disease Models, Animal; Edetic Acid; Humans; Microbial Collagenase; Protease Inhibitors; Steroids; Tropocollagen; Zinc Radioisotopes | 1975 |
5 trial(s) available for acetylcysteine and Disease Models, Animal
| Article | Year |
|---|---|
Efficacy of N-acetylcysteine in phenotypic suppression of mouse models of Niemann-Pick disease, type C1.
Topics: Acetylcysteine; Adolescent; Adult; Animals; Child; Child, Preschool; Cross-Over Studies; Disease Models, Animal; Double-Blind Method; Female; Gene Expression; Humans; Liver; Male; Mice; Mice, Knockout; Niemann-Pick Disease, Type C; Oxidative Stress; Ubiquinone; Young Adult | 2013 |
N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI.
Topics: Acetylcysteine; Aldehydes; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Double-Blind Method; Energy Metabolism; Glutathione; Male; Maze Learning; Mitochondria; Neuroprotective Agents; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 2014 |
N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Double-Blind Method; Drug Delivery Systems; Electron Transport Chain Complex Proteins; Energy Metabolism; Female; Ganglia, Spinal; Lameness, Animal; Mitochondria; Motor Activity; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Synapses; Time Factors | 2014 |
Intraluminal casein model of necrotizing enterocolitis for assessment of mucosal destruction, bacterial translocation, and the effects of allopurinol and N-acetylcysteine.
Topics: Acetylcysteine; Allopurinol; Analysis of Variance; Animals; Animals, Newborn; Bacterial Translocation; Caseins; Disease Models, Animal; Enterocolitis, Necrotizing; Ileum; Intestinal Mucosa; Lymphatic System; Male; Swine | 2002 |
Effects of Prussian blue and N-acetylcysteine on thallium toxicity in mice.
Topics: Acetylcysteine; Acute Disease; Administration, Oral; Animals; Antidotes; Disease Models, Animal; Drug Therapy, Combination; Female; Ferrocyanides; Injections, Intraperitoneal; Mice; Poisoning; Thallium | 1997 |
727 other study(ies) available for acetylcysteine and Disease Models, Animal
| Article | Year |
|---|---|
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila.
Topics: Animals; Disease Models, Animal; Drosophila; Drosophila Proteins; Drug Evaluation, Preclinical; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; gamma-Aminobutyric Acid; Glutamic Acid; Male; Molecular Weight; Mutation; Phenotype; Pyridines; RNA, Messenger; Small Molecule Libraries | 2008 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
N-Acetyl-l-cysteine restores reproductive defects caused by Ggt1 deletion in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Female; gamma-Glutamyltransferase; Infertility; Mice; Polycystic Ovary Syndrome | 2021 |
Targeting Oxidative Stress with Antioxidant Duotherapy after Experimental Traumatic Brain Injury.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Injuries, Traumatic; Cell Line; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expression; Heme Oxygenase-1; Isothiocyanates; Male; Mice, Inbred C57BL; Microglia; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; Sulfoxides | 2021 |
Clinically translatable gold nanozymes with broad spectrum antioxidant and anti-inflammatory activity for alleviating acute kidney injury.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Drug Delivery Systems; Female; Gold; HEK293 Cells; Humans; Kidney; Male; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2021 |
Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome.
Topics: Acetylcysteine; Animals; Antioxidants; Dihydrotestosterone; Disease Models, Animal; Female; Ferroptosis; Glutathione; Insulin Resistance; Iron; Male; Malondialdehyde; Mitochondria; Oxidative Phosphorylation; Phospholipid Hydroperoxide Glutathione Peroxidase; Placenta; Polycystic Ovary Syndrome; Pregnancy; Rats, Sprague-Dawley; Signal Transduction; Uterus | 2021 |
N-Acetyl Cysteine, Selenium, and Ascorbic Acid Rescue Diabetic Cardiac Hypertrophy via Mitochondrial-Associated Redox Regulators.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Ascorbic Acid; Biomarkers; Blood Glucose; Body Weight; Calcium; Cardiomegaly; Cardiotonic Agents; Cytochromes c; Diabetic Cardiomyopathies; Disease Models, Animal; Down-Regulation; GATA4 Transcription Factor; Lipid Peroxidation; Lipids; Mitochondria, Heart; Myocardium; Oxidation-Reduction; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Selenium | 2021 |
N-Acetylcysteine (NAC) Inhibits Synthesis of IL-18 in Macrophage by Suppressing NLRP3 Expression to Reduce the Production of IFN-
Topics: Acetylcysteine; Aged; Animals; Case-Control Studies; Computational Biology; Cytokines; Disease Models, Animal; Female; Humans; Interferon-gamma; Interleukin-18; Killer Cells, Natural; Lung; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Disease, Chronic Obstructive | 2021 |
N-acetylcysteine aggravates seizures while improving depressive-like and cognitive impairment comorbidities in the WAG/Rij rat model of absence epilepsy.
Topics: Acetylcysteine; Animals; Cognitive Dysfunction; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Humans; Rats; Seizures | 2022 |
N-Acetylcysteine and Aripiprazole Improve Social Behavior and Cognition and Modulate Brain BDNF Levels in a Rat Model of Schizophrenia.
Topics: Acetylcysteine; Animals; Antipsychotic Agents; Aripiprazole; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition; Cognition Disorders; Disease Models, Animal; Female; Hippocampus; Prefrontal Cortex; Pregnancy; Quinolones; Rats; Rats, Sprague-Dawley; Schizophrenia; Social Behavior | 2022 |
Chronic N-Acetylcysteine Treatment Prevents Amphetamine-Induced Hyperactivity in Heterozygous
Topics: Acetylcysteine; Amphetamine; Animals; Disease Models, Animal; Dopamine; Female; Glycogen Synthase Kinase 3; Humans; Mice; Nerve Tissue Proteins; Pregnancy; Receptors, Dopamine; Schizophrenia | 2022 |
Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Fibroblasts; Hepatocytes; Humans; Liver; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Wharton Jelly | 2022 |
Induction of ferroptosis promotes vascular smooth muscle cell phenotypic switching and aggravates neointimal hyperplasia in mice.
Topics: Acetylcysteine; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Ferroptosis; Hyperplasia; Iron; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Osteopontin; Phenotype; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Smooth Muscle Myosins | 2022 |
Evaluation the cognition-improvement effects of N-acetyl cysteine in experimental temporal lobe epilepsy in rat.
Topics: Acetylcysteine; Animals; Cognition; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Hippocampus; Kainic Acid; Maze Learning; Memory Disorders; Rats; TOR Serine-Threonine Kinases | 2023 |
N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions.
Topics: Acetylcysteine; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy; Myoclonus; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Superoxide Dismutase | 2023 |
Intestine and brain TLR-4 modulation following N-acetyl-cysteine treatment in NEC rodent model.
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain; Brain Injuries; Disease Models, Animal; Enterocolitis, Necrotizing; Glutathione; Ileum; Intestines; Rats; Rats, Sprague-Dawley; Rodentia; Toll-Like Receptor 4 | 2023 |
N-acetylcysteine improves autism-like behavior by recovering autophagic deficiency and decreasing Notch-1/Hes-1 pathway activity.
Topics: Acetylcysteine; Animals; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Female; Humans; Neuroblastoma; Prenatal Exposure Delayed Effects; Rats; Valproic Acid | 2023 |
Comparing the acute and chronic effects of metformin and antioxidant protective effects of N-acetyl cysteine on memory retrieval and oxidative stress in rats with Alzheimer's disease.
Topics: Acetylcysteine; Alzheimer Disease; Animals; Antioxidants; Disease Models, Animal; Maze Learning; Metformin; Oxidative Stress; Rats; Streptozocin | 2023 |
Effects of N-acetylcysteine and acetyl-L-carnitine on acute PTZ-induced seizures in larval and adult zebrafish.
Topics: Acetylcarnitine; Acetylcysteine; Adult; Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Humans; Larva; Pentylenetetrazole; Seizures; Zebrafish | 2023 |
Investigating the Possible Protective Role of Direct Intra-arterial Administration of Mannitol and N-Acetylcysteine and Per Os Administration of Simvastatin Against Contrast-Induced Nephropathy: An Experimental Study in a Rabbit Model.
Topics: Acetylcysteine; Acute Kidney Injury; Administration, Oral; Animals; Contrast Media; Disease Models, Animal; Diuretics, Osmotic; Humans; Infusions, Intra-Arterial; Iohexol; Male; Mannitol; Rabbits; Simvastatin | 2019 |
Oxidants Regulated Diaphragm Proteolysis during Mechanical Ventilation in Rats.
Topics: Acetylcysteine; Animals; Autophagy; Diaphragm; Disease Models, Animal; Free Radical Scavengers; Male; Muscular Atrophy; Oxidants; Proteolysis; Rats; Rats, Wistar; Respiration, Artificial | 2019 |
Critical Limb Ischaemia Exacerbates Mitochondrial Dysfunction in ApoE-/- Mice Compared with ApoE+/+ Mice, but N-acetyl Cysteine still Confers Protection.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium; Critical Illness; Disease Models, Animal; Hyperlipidemias; Ischemia; Mice, Knockout, ApoE; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Stress; Peripheral Arterial Disease; Reactive Oxygen Species | 2019 |
N-Acetylcysteine prevents the decreases in cardiac collagen I/III ratio and systolic function in neonatal mice with prenatal alcohol exposure.
Topics: Acetylcysteine; Alcoholism; Animals; Animals, Newborn; Cell Proliferation; Collagen Type I; Coronary Vessels; Disease Models, Animal; Ethanol; Female; Fibroblasts; Mice; Pregnancy; Prenatal Exposure Delayed Effects | 2019 |
N-Acetylcysteine Resolves Placental Inflammatory-Vasculopathic Changes in Mice Consuming a High-Fat Diet.
Topics: Acetylcysteine; Animals; Diet, High-Fat; Disease Models, Animal; Female; Inflammation; Male; Maternal Nutritional Physiological Phenomena; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications; Vascular Diseases | 2019 |
Temporal Dynamics of Reactive Oxygen and Nitrogen Species and NF-κB Activation During Acute and Chronic T Cell-Driven Inflammation.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Female; Free Radical Scavengers; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Optical Imaging; Picryl Chloride; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; T-Lymphocytes | 2020 |
N-Acetyl Cysteine Attenuates the Sarcopenia and Muscle Apoptosis Induced by Chronic Liver Disease.
Topics: Acetylcysteine; Aging; Animals; Apoptosis; Disease Models, Animal; End Stage Liver Disease; Humans; Mice; Muscle Fibers, Skeletal; Muscular Atrophy; Oxidative Stress; Pyridines; Sarcopenia | 2019 |
Photoprotection But Not N-acetylcysteine Improves Intestinal Blood Flow and Oxidation Status in Parenterally Fed Piglets.
Topics: Acetylcysteine; Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Intestines; Light; Male; Mesenteric Arteries; Oxidation-Reduction; Parenteral Nutrition, Total; Random Allocation; Swine | 2019 |
The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice.
Topics: Acetylcysteine; Adenocarcinoma of Lung; Animals; Antioxidants; Disease Models, Animal; Female; Humans; Lung; Lung Diseases; Lung Neoplasms; Male; Mice; Mice, Knockout; Oxidative Stress; Proto-Oncogene Proteins c-jun; Pulmonary Emphysema; Reactive Oxygen Species | 2019 |
Gold nanoparticles potentiates N-acetylcysteine effects on neurochemicals alterations in rats after polymicrobial sepsis.
Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Disease Models, Animal; Gold; Hippocampus; Inflammation; Male; Metal Nanoparticles; Mitochondria; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis | 2020 |
Therapeutic targeting of mitochondrial ROS ameliorates murine model of volume overload cardiomyopathy.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiomyopathies; Disease Models, Animal; Heart Failure; Male; Mice, Inbred C57BL; Mitochondria; Molecular Targeted Therapy; Myocytes, Cardiac; Reactive Oxygen Species | 2019 |
Systemic LPS-induced neuroinflammation increases the susceptibility for proteasome inhibition-induced degeneration of the nigrostriatal pathway.
Topics: Acetylcysteine; Animals; Behavior, Animal; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Illness Behavior; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Nerve Degeneration; Neural Pathways; Proteasome Inhibitors; Substantia Nigra | 2019 |
Early sarcomere and metabolic defects in a zebrafish
Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Antioxidants; Arrhythmias, Cardiac; Cardiac Conduction System Disease; Cardiomyopathies; Disease Models, Animal; Electrocardiography; Gene Expression Regulation; Homeodomain Proteins; Larva; Mitochondria, Heart; Sarcomeres; Stress, Physiological; Transcription Factors; Zebrafish; Zebrafish Proteins | 2019 |
Neuroprotective effects of N-acetylcysteine via inhibition of matrix metalloproteinase in a mouse model of transient global cerebral ischemia.
Topics: Acetylcysteine; Animals; Brain; Brain Ischemia; Disease Models, Animal; Hippocampus; Injections, Intraperitoneal; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents | 2020 |
Sildenafil and tadalafil reduce the risk of contrast-induced nephropathy by modulating the oxidant/antioxidant balance in a murine model.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Contrast Media; Disease Models, Animal; Glutathione; Kidney Diseases; Male; Mice; Oxidants; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Sildenafil Citrate; Tadalafil; Thiobarbituric Acid Reactive Substances | 2020 |
Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected.
Topics: Acetylcysteine; Animals; Aqueous Humor; Cytochrome P-450 CYP1B1; Disease Models, Animal; DNA Adducts; DNA Damage; DNA, Mitochondrial; Endothelium, Corneal; Estrogens; Female; Free Radical Scavengers; Fuchs' Endothelial Dystrophy; Humans; Male; Mice; Oxidative Stress; Reactive Oxygen Species; Severity of Illness Index; Ultraviolet Rays | 2020 |
Topical combination of meldonium and N-acetyl cysteine relieves allodynia in rat models of CRPS-1 and peripheral neuropathic pain by enhancing NO-mediated tissue oxygenation.
Topics: Acetylcysteine; Administration, Topical; Animals; Disease Models, Animal; Hyperalgesia; Male; Methylhydrazines; Neuralgia; Nitric Oxide; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Reflex Sympathetic Dystrophy | 2020 |
N-acetylcysteine reduces amphotericin B deoxycholate nephrotoxicity and improves the outcome of murine cryptococcosis.
Topics: Acetylcysteine; Amphotericin B; Animals; Antifungal Agents; Brain; Creatinine; Cryptococcosis; Cryptococcus; Deoxycholic Acid; Disease Models, Animal; Drug Combinations; Drug Repositioning; Female; Kidney; Lung; Macrophages; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Reactive Oxygen Species | 2020 |
Evaluation of selected protein biomarkers of renal function in rats with an experimental model of acute cyclophosphamide-induced cystitis treated with N-acetylcysteine.
Topics: Acetylcysteine; Animals; Biomarkers; Cyclophosphamide; Cystitis; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney Diseases; Kidney Tubules; Male; Rats; Rats, Wistar; Urinary Bladder | 2019 |
N-Acetyl-L-Cysteine Reduces Fibrosis and Improves Muscle Function After Acute Compartment Syndrome Injury.
Topics: Acetylcysteine; Analysis of Variance; Animals; Compartment Syndromes; Disease Models, Animal; Female; Free Radical Scavengers; Muscle, Skeletal; Protective Factors; Rats, Inbred Lew; Real-Time Polymerase Chain Reaction | 2020 |
Topics: Acetylcysteine; Animals; Biofilms; Chronic Disease; Diabetes Mellitus; Disease Models, Animal; DNA, Bacterial; Extracellular Polymeric Substance Matrix; Free Radical Scavengers; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Obese; Microbial Viability; Microscopy, Confocal; Microscopy, Fluorescence; Oxidative Stress; Protein Biosynthesis; Pseudomonas aeruginosa; Pseudomonas Infections; Wound Infection; Wounds and Injuries | 2020 |
N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression.
Topics: Acetylcysteine; Animals; Asthma; Bronchoalveolar Lavage Fluid; Claudins; Disease Models, Animal; Female; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin | 2020 |
The inhibition of reactive oxygen species (ROS) by antioxidants inhibits the release of an autophagy marker in ectopic endometrial cells.
Topics: Acetylcysteine; Animals; Antioxidants; Autophagy; Beclin-1; Blotting, Western; Catalase; Disease Models, Animal; Female; In Situ Hybridization, Fluorescence; Microtubule-Associated Proteins; Rats; Reactive Oxygen Species | 2020 |
Cysteine becomes conditionally essential during hypobaric hypoxia and regulates adaptive neuro-physiological responses through CBS/H
Topics: Acetylcysteine; Adaptation, Physiological; Adult; Altitude Sickness; Animals; Brain; Cerebrovascular Circulation; Cystathionine beta-Synthase; Cysteine; Disease Models, Animal; Energy Metabolism; Humans; Hydrogen Sulfide; Hypoxia; Male; Oxygen Consumption; Prodrugs; Rats; Young Adult | 2020 |
N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder.
Topics: Acetylcysteine; Animals; Antioxidants; Caseins; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Models, Animal; Disease Progression; Glycation End Products, Advanced; Humans; Kidney; Lipid Peroxidation; Male; Mutation; Nuclear Proteins; Oxidative Stress; Parathyroid Hormone; Rats; Tibia; X-Ray Microtomography | 2020 |
Therapeutic effect of N-acetylcysteine on chemotherapy-induced liver injury.
Topics: Acetylcysteine; Adolescent; Animals; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Disease Models, Animal; Female; Humans; Liver; Male; Retrospective Studies | 2020 |
Dexmedetomidine alleviated neuropathic pain in dorsal root ganglion neurons by inhibition of anaerobic glycolysis activity and enhancement of ROS tolerance.
Topics: Acetylcysteine; Anaerobiosis; Animals; Apoptosis; Cells, Cultured; Dexmedetomidine; Disease Models, Animal; Ganglia, Spinal; Glucose; Glycolysis; Humans; Hydrogen Peroxide; Neuralgia; Neurons; Primary Cell Culture; Rats; Reactive Oxygen Species | 2020 |
Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Diabetic Cardiomyopathies; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Protein Deglycase DJ-1; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Protective Effect of N-Acetylcysteine Pretreatment on Acute Kidney Injury in Septic Rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cecum; Disease Models, Animal; Kidney; Ligation; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Sepsis | 2020 |
Quantitative analysis of intervertebral disc degeneration using Q-space imaging in a rat model.
Topics: Acetylcysteine; Animals; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Feasibility Studies; Female; Free Radical Scavengers; Intervertebral Disc Degeneration; Rats, Wistar | 2020 |
N-acetylcysteine differentially regulates the populations of bone marrow and circulating endothelial progenitor cells in mice with limb ischemia.
Topics: Acetylcysteine; Angiogenesis Inducing Agents; Animals; Antioxidants; Apoptosis; Bone Marrow Cells; Cell Proliferation; Disease Models, Animal; Endothelial Progenitor Cells; Hindlimb; Ischemia; Male; Mice, Inbred C57BL; Muscle, Skeletal; Neovascularization, Physiologic; Oxidative Stress; Phenotype; Reactive Oxygen Species; Recovery of Function | 2020 |
Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia.
Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Benzodioxoles; Bile Ducts; Biliary Atresia; Cell Line; Cyclic GMP; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Free Radical Scavengers; Glutathione; Humans; Oxidation-Reduction; Proteostasis; Signal Transduction; Zebrafish | 2020 |
Treatment of dilated cardiomyopathy in a mouse model of Friedreich's ataxia using N-acetylcysteine and identification of alterations in microRNA expression that could be involved in its pathogenesis.
Topics: Acetylcysteine; Animals; Basic-Leucine Zipper Transcription Factors; Cardiomyopathy, Dilated; Cell Line, Tumor; Disease Models, Animal; Frataxin; Friedreich Ataxia; Gene Expression Regulation; Humans; Iron-Binding Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Mice, Knockout; MicroRNAs; Myocytes, Cardiac; NF-E2-Related Factor 2; Sulfoxides | 2020 |
Protective effects of N-acetylcysteine on a chemical-induced murine model of asthma.
Topics: Acetylcysteine; Allergens; Animals; Anti-Asthmatic Agents; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Glutathione; Immunoglobulin E; Interleukin-4; Interleukin-5; Leukocyte Count; Lung; Male; Mice, Inbred BALB C; Neutrophils; Superoxide Dismutase; Toluene 2,4-Diisocyanate | 2021 |
Histological analysis of the intestinal wall of newborn rats submitted to hypoxia and reoxygenation to evaluate the protective effect of N-Acetylcysteine.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Enterocolitis, Necrotizing; Female; Hypoxia; Ileum; Male; Pregnancy; Protective Agents; Rats, Wistar; Reference Values; Reproducibility of Results; Time Factors; Treatment Outcome | 2020 |
Topics: Acetylcysteine; Animals; Antioxidants; Body Mass Index; Disease Models, Animal; Humans; Lipid Peroxidation; Mice; Muscle Strength; Muscle, Skeletal; Muscular Dystrophies, Limb-Girdle; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Treatment Outcome | 2020 |
The effects of specific and non-specific phosphodiesterase inhibitors and N-acetylcysteine on oxidative stress and remote organ injury in two-hit trauma model.
Topics: Acetylcysteine; Animals; Antioxidants; Burns; Disease Models, Animal; Oxidative Stress; Peritonitis; Phosphodiesterase Inhibitors; Rats; Wounds and Injuries | 2020 |
Mechanistic study of mtROS-JNK-SOD2 signaling in bupivacaine-induced neuron oxidative stress.
Topics: Acetylcysteine; Animals; Anthracenes; Antioxidants; Bupivacaine; Cell Line, Tumor; Cyclic N-Oxides; Disease Models, Animal; Gene Knockdown Techniques; Humans; Injections, Spinal; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mitochondria; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Rats; Reactive Oxygen Species; RNA, Small Interfering; Superoxide Dismutase; Transcriptional Activation | 2020 |
Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions.
Topics: Acetylcysteine; Animals; Anxiety; Autistic Disorder; Chromosome Deletion; Chromosomes, Mammalian; Disease Models, Animal; Gene-Environment Interaction; Humans; Male; Mice, Inbred C57BL; Motor Activity; Phenotype; Social Behavior; Social Interaction | 2020 |
Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidant Response Elements; Apoptosis; Brain; Caspase 3; DEAD-box RNA Helicases; Disease Models, Animal; Down-Regulation; Female; Gene Knockdown Techniques; Hippocampus; Humans; Male; Membrane Potential, Mitochondrial; Mice, Transgenic; Neurons; Neurotoxicity Syndromes; NF-E2-Related Factor 2; Peptide Fragments; Presenilin-1; Reactive Oxygen Species; Ribonuclease III; Spatial Learning | 2020 |
A Drosophila model of Friedreich ataxia with CRISPR/Cas9 insertion of GAA repeats in the frataxin gene reveals in vivo protection by N-acetyl cysteine.
Topics: Acetylcysteine; Animals; CRISPR-Cas Systems; Disease Models, Animal; Drosophila melanogaster; Frataxin; Friedreich Ataxia; Humans; Introns; Iron-Binding Proteins; Oxidative Stress; RNA-Seq; Trinucleotide Repeat Expansion | 2020 |
I-152, a supplier of N-acetyl-cysteine and cysteamine, inhibits immunoglobulin secretion and plasma cell maturation in LP-BM5 murine leukemia retrovirus-infected mice by affecting the unfolded protein response.
Topics: Acetylcysteine; Animals; Antiviral Agents; Cysteamine; Disease Models, Animal; Female; Immunoglobulins; Injections, Intraperitoneal; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Plasma Cells; Protein Unfolding; Retroviridae Infections; Tumor Virus Infections; Unfolded Protein Response | 2020 |
Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats.
Topics: Acetylcysteine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Disease Models, Animal; Female; Gamma Rays; Humans; MAP Kinase Signaling System; NADPH Oxidase 4; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2020 |
The potential protective role of folic acid against acetaminophen-induced hepatotoxicity and nephrotoxicity in rats.
Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Folic Acid; Free Radical Scavengers; Oxidative Stress; Rats, Sprague-Dawley | 2021 |
Role of oxidative stress in clofazimine-induced cardiac dysfunction in a zebrafish model.
Topics: Acetylcysteine; Animals; Antitubercular Agents; Clofazimine; Disease Models, Animal; Gene Expression Profiling; Heart Diseases; Oxidative Stress; Zebrafish | 2020 |
Maternal N-acetyl-cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model.
Topics: Acetylcysteine; Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Injuries; Caspase 3; Disease Models, Animal; Enterocolitis, Necrotizing; Female; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-6; Nitric Oxide Synthase Type I; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2021 |
N-acetylcysteine protects neonatal mice from ventricular hypertrophy induced by maternal obesity in a sex-specific manner.
Topics: Acetylcysteine; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Female; Fibrosis; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Maternal Nutritional Physiological Phenomena; Mice, Inbred C57BL; Obesity, Maternal; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Electrophysiological assessment and pharmacological treatment of blast-induced tinnitus.
Topics: Acetylcysteine; Animals; Benzenesulfonates; Biomarkers; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory, Inner; Hearing Loss, Noise-Induced; Male; Rats; Tinnitus | 2021 |
Improvement of the skeletal phenotype in a mouse model of diastrophic dysplasia after postnatal treatment with N-acetylcysteine.
Topics: Acetylcysteine; Animals; Animals, Newborn; Bone Density; Disease Models, Animal; Dwarfism; Free Radical Scavengers; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Phenotype | 2021 |
Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease.
Topics: Acetylcysteine; Animals; Caenorhabditis elegans; Disease Models, Animal; Drug Synergism; Electron Transport Complex I; Free Radical Scavengers; Glucose; Humans; Longevity; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Mutation; Niacin; Oxidative Stress; Zebrafish | 2021 |
Deficiency of voltage-gated proton channel Hv1 aggravates ovalbumin-induced allergic lung asthma in mice.
Topics: Acetylcysteine; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Goblet Cells; Hyperplasia; Ion Channels; Mice, Knockout; NADPH Oxidases; Ovalbumin; Reactive Oxygen Species; T-Lymphocytes, Regulatory; Th1 Cells; Th17 Cells; Th2 Cells | 2021 |
Effectiveness of N-Acetylcysteine in the Treatment of Renal Deterioration Caused by Long-Term Exposure to Bisphenol A.
Topics: Acetylcysteine; Administration, Oral; Animals; Azotemia; Benzhydryl Compounds; Disease Models, Animal; Glomerular Filtration Rate; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Phenols; Proteinuria; Rats; Rats, Wistar; Signal Transduction | 2021 |
S-Allylmercapto-N-acetylcysteine ameliorates elastase-induced chronic obstructive pulmonary disease in mice via regulating autophagy.
Topics: A549 Cells; Acetylcysteine; Allyl Compounds; Animals; Autophagy; Disease Models, Animal; Humans; Inflammation; Lung; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Pancreatic Elastase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Disease, Chronic Obstructive; Swine; TOR Serine-Threonine Kinases; Up-Regulation; Weight Loss | 2021 |
Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis.
Topics: Acetylcysteine; Adult; Animals; Combined Modality Therapy; Disease Models, Animal; Exercise Therapy; Female; Glutamate-Cysteine Ligase; Humans; Interneurons; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Parvalbumins; Psychotic Disorders; Receptor for Advanced Glycation End Products; Signal Transduction; Translational Research, Biomedical | 2021 |
Psychosocial impairment following mild blast-induced traumatic brain injury in rats.
Topics: Acetylcysteine; Acrolein; Animals; Blast Injuries; Brain; Brain Concussion; Brain Injuries; Disease Models, Animal; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Psychosocial Functioning; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2021 |
KLF4 Upregulation in Atherosclerotic Thoracic Aortas: Exploring the Protective Effect of Colchicine-based Regimens in a Hyperlipidemic Rabbit Model.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Colchicine; Disease Models, Animal; Drug Therapy, Combination; Fibric Acids; Hyperlipidemias; Kruppel-Like Factor 4; Male; Plaque, Atherosclerotic; Rabbits; Up-Regulation | 2022 |
Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Methylazoxymethanol Acetate; Rats; Schizophrenia; Thalamic Nuclei | 2021 |
Preliminary therapeutic and mechanistic evaluation of S-allylmercapto-N-acetylcysteine in the treatment of pulmonary emphysema.
Topics: Acetylcysteine; Allyl Compounds; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Chemokines; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Male; Mice; Molecular Docking Simulation; Network Pharmacology; Protein Interaction Mapping; Protein Interaction Maps; Pulmonary Emphysema; Renin-Angiotensin System; Signal Transduction | 2021 |
Systemic administration of N-acetylcysteine during the extinction period and on the reinstatement day decreased the maintenance of morphine rewarding properties in the rats.
Topics: Acetylcysteine; Animals; Antioxidants; Behavior, Animal; Conditioning, Classical; Disease Models, Animal; Locomotion; Morphine; Morphine Dependence; Narcotics; Rats; Rats, Wistar; Reinforcement, Psychology; Reward | 2021 |
Topics: Acetylcysteine; Anesthesia, Local; Anesthetics, Local; Animals; Cicatrix; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Male; Rats; Rats, Sprague-Dawley; Wound Healing | 2021 |
Neurological impairment caused by Schistosoma mansoni systemic infection exhibits early features of idiopathic neurodegenerative disease.
Topics: Acetylcysteine; Animals; Anthelmintics; Astrocytes; Deferoxamine; Disease Models, Animal; Free Radical Scavengers; Male; Mice; Microglia; Morris Water Maze Test; Neurodegenerative Diseases; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Siderophores | 2021 |
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; Carrier Proteins; Cell Cycle Proteins; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Kidney Tubules, Proximal; Lipopolysaccharides; Male; MAP Kinase Kinase Kinase 5; Mice, Inbred C57BL; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Peroxides; Sepsis | 2021 |
In Vitro and In Vivo Analysis of Ochratoxin A-Derived Glucuronides and Mercapturic Acids as Biomarkers of Exposure.
Topics: Acetylcysteine; Animals; Biomarkers; Disease Models, Animal; Environmental Monitoring; Food Contamination; Glucuronides; In Vitro Techniques; Ochratoxins; Rats; Species Specificity; Swine; Swine, Miniature | 2021 |
Single Dose of N-Acetylcysteine in Local Anesthesia Increases Expression of HIF1α, MAPK1, TGFβ1 and Growth Factors in Rat Wound Healing.
Topics: Acetylcysteine; Anesthesia, Local; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Disease Models, Animal; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Mitogen-Activated Protein Kinase 1; Oxidative Stress; Peroxidase; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Wound Healing | 2021 |
N-Acetylcysteine Prevents Low T3 Syndrome and Attenuates Cardiac Dysfunction in a Male Rat Model of Myocardial Infarction.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Euthyroid Sick Syndromes; Male; Myocardial Infarction; Myocytes, Cardiac; Protein Carbonylation; Rats; Rats, Wistar; Thyroid Hormones; Ventricular Dysfunction | 2017 |
Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload.
Topics: Acetylcysteine; Animals; Antioxidants; beta Catenin; Disease Models, Animal; Fatty Liver; Female; Hemochromatosis; Humans; Iron Overload; Liver; Liver Cirrhosis; Male; Mice; Mice, Knockout; Oxidative Stress; Signal Transduction | 2017 |
Influence of N-acetyl cysteine on beta-amyloid-induced Alzheimer's disease in a rat model: A behavioral and electrophysiological study.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Disease Models, Animal; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Memory; Neurons; Rats; Rats, Wistar | 2017 |
Preventing, treating, and predicting barbering: A fundamental role for biomarkers of oxidative stress in a mouse model of Trichotillomania.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Biomarkers; Deoxyguanosine; Disease Models, Animal; Grooming; Mice; Mice, Inbred C57BL; Oxidative Stress; Trichotillomania | 2017 |
Nigral injection of a proteasomal inhibitor, lactacystin, induces widespread glial cell activation and shows various phenotypes of Parkinson's disease in young and adult mouse.
Topics: Acetylcysteine; Age Factors; Animals; Calcium-Binding Proteins; Cysteine Proteinase Inhibitors; Disease Models, Animal; Forelimb; Glial Fibrillary Acidic Protein; Glutamate Decarboxylase; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microinjections; Neuroglia; Neurotransmitter Agents; Parkinson Disease; Psychomotor Performance; Substantia Nigra; Synucleins; Tyrosine 3-Monooxygenase | 2017 |
Protective Role of N-Acetylcysteine on Isoprenaline-Induced Myocardial Injury: Histological, Immunohistochemical and Morphometric Study.
Topics: Acetylcysteine; Actins; Animals; Collagen; Cytoprotection; Disease Models, Animal; Immunohistochemistry; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Proliferating Cell Nuclear Antigen; Rats, Wistar; Time Factors | 2018 |
Prevention and reversal of selenite-induced cataracts by N-acetylcysteine amide in Wistar rats.
Topics: Acetylcysteine; Animals; Blotting, Western; Cataract; Disease Models, Animal; Lens, Crystalline; Male; Ophthalmic Solutions; Oxidative Stress; Rats; Rats, Wistar; Selenious Acid | 2017 |
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Topics: Acetylcysteine; Animals; Brain; Disease Models, Animal; Fluorine Radioisotopes; Image Processing, Computer-Assisted; Male; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tetrabenazine | 2017 |
N-acetylcysteine prevents the development of gastritis induced by Helicobacter pylori infection.
Topics: Acetylcysteine; Animals; Asymptomatic Infections; Bacterial Load; Culture Media; Diet; Disease Models, Animal; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Humans; Stomach | 2017 |
Potent Thrombolytic Effect of
Topics: Acetylcysteine; Animals; Blood Platelets; Chlorides; Disease Models, Animal; Ferric Compounds; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Male; Mice; Platelet Aggregation; Ristocetin; Thromboembolism; Thrombosis; Tissue Plasminogen Activator; von Willebrand Factor | 2017 |
N-acetylcysteine treatment attenuates the cognitive impairment and synaptic plasticity loss induced by streptozotocin.
Topics: Acetylcholinesterase; Acetylcysteine; Animals; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Immunohistochemistry; Male; Maze Learning; Mice; Motor Activity; Neuronal Plasticity; Neuroprotective Agents; Oxidative Stress; Physostigmine; Receptor, trkB; Streptozocin; Superoxide Dismutase | 2017 |
Sialic acid deficiency is associated with oxidative stress leading to muscle atrophy and weakness in GNE myopathy.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Distal Myopathies; Humans; Mice; Mice, Knockout; Multienzyme Complexes; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; N-Acetylneuraminic Acid; Oxidative Stress; Reactive Oxygen Species | 2017 |
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Cognitive Dysfunction; Disease Models, Animal; Drug Therapy, Combination; Epilepsy; Hippocampus; HMG-Box Domains; HMGB1 Protein; Isothiocyanates; Male; Nerve Degeneration; Neurons; Oxidative Stress; Rats; Sulfoxides | 2017 |
Vitamin D improves functional outcomes in neonatal hypoxic ischemic male rats treated with N-acetylcysteine and hypothermia.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Calcitriol; Disease Models, Animal; Female; Hippocampus; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Male; Maze Learning; Memory; Motor Skills; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Sex Characteristics; Vitamin D; Vitamin D3 24-Hydroxylase | 2017 |
The Protective Effect of N-Acetylcysteine on Ionizing Radiation Induced Ovarian Failure and Loss of Ovarian Reserve in Female Mouse.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Embryo Implantation; Endometrium; Female; Humans; Mice; Ovarian Follicle; Ovarian Reserve; Primary Ovarian Insufficiency; Radiation-Protective Agents; Radiation, Ionizing | 2017 |
Uptake of dendrimer-drug by different cell types in the hippocampus after hypoxic-ischemic insult in neonatal mice: Effects of injury, microglial activation and hypothermia.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Cerebral Palsy; Dendrimers; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Female; Hippocampus; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Mice; Microglia; Tissue Distribution | 2017 |
Minocycline plus N-acteylcysteine induces remyelination, synergistically protects oligodendrocytes and modifies neuroinflammation in a rat model of mild traumatic brain injury.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Brain Injuries, Traumatic; Disease Models, Animal; Drug Synergism; Inflammation; Male; Minocycline; Oligodendroglia; Rats; Rats, Sprague-Dawley; Remyelination | 2018 |
The role of oxidative stress in acute renal injury of newborn rats exposed to hypoxia and endotoxin.
Topics: Acetylcysteine; Acute Kidney Injury; Acute-Phase Proteins; Animals; Animals, Newborn; Antioxidants; Biomarkers; Blood Urea Nitrogen; Cell Adhesion Molecules; Disease Models, Animal; Gene Expression; Humans; Hypoxia; Infant; Lipocalin-2; Lipocalins; Lipopolysaccharides; Oxidative Stress; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species | 2017 |
Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril.
Topics: Acetylcysteine; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension; Light; Male; Melatonin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ventricular Remodeling | 2017 |
The Involvement of the Oxidative Stress in Murine Blue LED Light-Induced Retinal Damage Model.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Electroretinography; Light; Male; Mice; Opsins; Oxidative Stress; Retina; Retinal Degeneration | 2017 |
Dietary alterations modulate susceptibility to Plasmodium infection.
Topics: Acetylcysteine; Animals; Antioxidants; Diet, High-Fat; Disease Models, Animal; Female; Gene Expression Profiling; Glucose Tolerance Test; Glucosephosphate Dehydrogenase Deficiency; Hep G2 Cells; Hepatocytes; Host-Parasite Interactions; Humans; Liver; Liver Diseases; Macrophages; Malaria; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Parasite Load; Plasmodium berghei; Reactive Oxygen Species; Sickle Cell Trait; Sporozoites | 2017 |
Lack of mitochondrial ferritin aggravated neurological deficits via enhancing oxidative stress in a traumatic brain injury murine model.
Topics: Acetylcysteine; Animals; Antioxidants; Brain; Brain Injuries, Traumatic; Cognitive Dysfunction; Disease Models, Animal; Ferritins; Glutathione; Malondialdehyde; Memory Disorders; Mice; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Nitric Oxide; Oxidative Stress; Superoxide Dismutase | 2017 |
Effects of particulate matter from straw burning on lung fibrosis in mice.
Topics: Acetylcysteine; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Fires; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Particle Size; Particulate Matter; Pulmonary Fibrosis; Random Allocation; Tumor Necrosis Factor-alpha | 2017 |
Antioxidant therapy in a mouse model of Duchenne muscular dystrophy: some promising results but with a weighty caveat.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Mice; Mice, Inbred mdx; Muscular Dystrophy, Duchenne | 2017 |
Potential protective effect of N-acetyl cysteine in acoustic trauma: An experimental study using scanning electron microscopy.
Topics: Acetylcysteine; Animals; Antioxidants; Cochlea; Disease Models, Animal; Epithelial Cells; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Microscopy, Electrochemical, Scanning; Noise; Oxidative Stress; Rats, Wistar; Stereocilia | 2017 |
Protective effects of deferasirox and N-acetyl-L-cysteine on iron overload-injured bone marrow.
Topics: Acetylcysteine; Animals; Benzoates; Colony-Forming Units Assay; Deferasirox; Disease Models, Animal; Flow Cytometry; Free Radical Scavengers; Hematopoiesis; Hematopoietic Stem Cells; Iron Chelating Agents; Iron Overload; Male; Mice, Inbred C57BL; Protective Agents; Reactive Oxygen Species; Reference Values; Reproducibility of Results; Time Factors; Treatment Outcome; Triazoles | 2017 |
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-6; Ischemia; Lactic Acid; Male; Muscle, Skeletal; Nitrates; Nitrites; Oxidative Stress; Oxygen; Oxygen Consumption; Peroxidase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vascular Endothelial Growth Factor A | 2018 |
Impairment of non-associative learning in a rat experimental model of preclinical stage of Parkinson's disease.
Topics: Acetylcysteine; Animals; Axons; Behavior, Animal; Cognitive Dysfunction; Disease Models, Animal; Dopaminergic Neurons; Humans; Learning; Mesencephalon; Parkinson Disease, Secondary; Prefrontal Cortex; Rats | 2017 |
Antioxidants improve IVF outcome and subsequent embryo development in the mouse.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Blastocyst; Culture Media; Disease Models, Animal; Embryo Culture Techniques; Embryonic Development; Female; Fertilization in Vitro; Hydrogen Peroxide; In Vitro Oocyte Maturation Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Oocyte Retrieval; Oocytes; Oxidative Stress; Oxygen; Spermatozoa; Thioctic Acid; Treatment Outcome | 2017 |
Behavioral and Biochemical Effects of N-Acetylcysteine in Zebrafish Acutely Exposed to Ethanol.
Topics: Acetylcysteine; Animals; Anxiety; Behavior, Animal; Brain; Disease Models, Animal; Ethanol; Female; Lipid Peroxidation; Male; Oxidative Stress; Zebrafish | 2018 |
N-acetylcysteine ameliorates contrast‑induced kidney injury in rats with unilateral hydronephrosis.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Biomarkers; Contrast Media; Disease Models, Animal; Hydronephrosis; Kidney Function Tests; Kidney Tubules; Male; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats | 2018 |
Temporal-Spatial Profiling of Pedunculopontine Galanin-Cholinergic Neurons in the Lactacystin Rat Model of Parkinson's Disease.
Topics: Acetylcysteine; Analysis of Variance; Animals; Choline O-Acetyltransferase; Cysteine Proteinase Inhibitors; Disease Models, Animal; Galanin; Male; Neurons; Parkinson Disease; Pedunculopontine Tegmental Nucleus; Rats; Rats, Sprague-Dawley; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2018 |
N-Acetylcysteine Attenuates the Development of Renal Fibrosis in Transgenic Mice with Dilated Cardiomyopathy.
Topics: Acetylcysteine; Animals; Cardio-Renal Syndrome; Cardiomyopathy, Dilated; Disease Models, Animal; Fibrosis; Glomerular Filtration Rate; Glutathione; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Myocardium; Nephritis; Oxidative Stress; Urinary Tract | 2017 |
Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome.
Topics: Acetylcysteine; Animals; Brain; Cytokines; Dendrimers; Disease Models, Animal; Free Radical Scavengers; Gene Expression Regulation; Glutamic Acid; Glutathione; Lipopolysaccharides; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Mutation; Rett Syndrome; Tissue Distribution | 2017 |
Antioxidant therapy for muscular dystrophy: caveat lector!
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Mice; Mice, Inbred mdx; Muscular Dystrophy, Duchenne | 2018 |
The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Auditory Fatigue; Brain Stem; Cochlea; Cytoprotection; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Furosemide; Gene Expression Regulation; Hearing; Hearing Loss; Inflammation Mediators; Kanamycin; Male; Oxidative Stress; Rats, Wistar; Reaction Time; Resveratrol | 2018 |
MicroRNA‑146a/NAPDH oxidase4 decreases reactive oxygen species generation and inflammation in a diabetic nephropathy model.
Topics: Acetylcysteine; Animals; Antagomirs; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Glucose; Humans; Inflammation; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; MicroRNAs; NADPH Oxidase 4; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase; Vascular Cell Adhesion Molecule-1 | 2018 |
N-acetyl-cysteine increases cellular dysfunction in progressive chronic kidney damage after acute kidney injury by dampening endogenous antioxidant responses.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Proliferation; Disease Models, Animal; Disease Progression; Energy Metabolism; Kidney; Male; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Mitochondria; NAD; Oxidative Stress; Phosphorylation; PPAR gamma; Renal Insufficiency, Chronic; Signal Transduction; Time Factors; Transforming Growth Factor beta1 | 2018 |
Oxidation of factor VIII increases its immunogenicity in mice with severe hemophilia A.
Topics: Acetylcysteine; Animals; Antibodies; Antigen-Presenting Cells; Disease Models, Animal; Factor VIII; Hemophilia A; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Oxidative Stress | 2018 |
Therapeutic N-Acetyl-Cysteine (Nac) Following Initiation of Maternal Inflammation Attenuates Long-Term Offspring Cerebral Injury, as Evident in Magnetic Resonance Imaging (MRI).
Topics: Acetylcysteine; Animals; Brain; Brain Injuries; Disease Models, Animal; Escherichia coli; Female; Inflammation; Lipopolysaccharides; Male; Neuroprotective Agents; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley | 2019 |
High Uric Acid Inhibits Cardiomyocyte Viability Through the ERK/P38 Pathway via Oxidative Stress.
Topics: Acetylcysteine; Animals; Cell Line; Cell Survival; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hyperuricemia; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Uric Acid | 2018 |
The Interaction of N-Acetylcysteine and Serum Transferrin Promotes Bacterial Biofilm Formation.
Topics: Acetylcysteine; Animals; Bacterial Infections; Bacterial Proteins; Biofilms; Disease Models, Animal; Extracellular Matrix; Humans; Male; Microscopy, Confocal; Pseudomonas aeruginosa; Rats; Rats, Sprague-Dawley; Staphylococcus aureus; Transcription Factors; Transferrins | 2018 |
The preventive effects of atorvastatin and N-acetyl cysteine in experimentally induced ischemia-reperfusion injury in rats.
Topics: Acetylcysteine; Animals; Atorvastatin; Catalase; Cecal Diseases; Cecum; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione Peroxidase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intestinal Volvulus; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase | 2018 |
Impaired Collateral Vessel Formation in Sickle Cell Disease.
Topics: Acetylcysteine; Anemia, Sickle Cell; Animals; Antioxidants; Blood Flow Velocity; Collateral Circulation; Disease Models, Animal; Female; Genetic Predisposition to Disease; Hindlimb; Hydrogen Peroxide; Ischemia; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Neovascularization, Physiologic; Neutrophils; Oxidative Stress; Phenotype; Regional Blood Flow; Time Factors | 2018 |
Effect of N-Acetylcysteine on Antioxidant Defense, Oxidative Modification, and Salivary Gland Function in a Rat Model of Insulin Resistance.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Insulin Resistance; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Salivary Glands | 2018 |
Cerebellum Susceptibility to Neonatal Asphyxia: Possible Protective Effects of N-Acetylcysteine Amide.
Topics: Acetylcysteine; Animals; Asphyxia Neonatorum; Disease Models, Animal; DNA, Mitochondrial; Humans; Infant, Newborn; Mutation Rate; Neuroprotective Agents; Proteolysis; Purkinje Cells; Swine | 2018 |
N-acetylcysteine protects against chorioretinal damage induced by photodynamic therapy for experimental choroidal neovascularization in a rat model.
Topics: Acetylcysteine; Animals; Choroidal Neovascularization; Disease Models, Animal; Fluorescein Angiography; Lasers, Semiconductor; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Inbred BN; Verteporfin | 2018 |
Comparison of the efficacy of various concentrations and combinations of serum, ethylenediaminetetraacetic acid, tetracycline, doxycycline, minocycline, and N-acetylcysteine for inhibition of collagenase activity in an in vitro corneal degradation model.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Collagenases; Cornea; Corneal Diseases; Disease Models, Animal; Dogs; Doxycycline; Edetic Acid; Horses; Matrix Metalloproteinase Inhibitors; Minocycline; Serum; Tetracycline | 2018 |
Protective Effects of Brain Infarction by
Topics: Acetylcysteine; Acrolein; Animals; Brain; Brain Infarction; Cell Line, Tumor; Disease Models, Animal; Glutathione; Mice; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species | 2018 |
Effect of tadalafil on reduction of necrosis in the ischemic zone in a rat comb burn model.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Disease Models, Animal; Disease Progression; Free Radical Scavengers; Ischemia; Naproxen; Necrosis; Random Allocation; Rats; Rats, Sprague-Dawley; Skin; Tadalafil; Vasodilator Agents | 2018 |
[EVALUATION OF NEUROPROTECTIVE ACTIVITY OF COMPLEX IMPACT OF MAGNESIUM OF SULFATE, LAMOTRYGINE AND N-ACETYLCYSTEINE UNDER CONDITIONS OF COMBINED NORMOBARIC HYPOXIA WITH LIGATION OF RIGHT CAROTID ARTERY IN RATS].
Topics: Acetylcysteine; Administration, Oral; Animals; Animals, Outbred Strains; Brain Ischemia; Carotid Arteries; Cerebrovascular Disorders; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Injections, Intraperitoneal; Lamotrigine; Magnesium Sulfate; Male; Neuroprotective Agents; Rats; Stroke | 2018 |
N,N'-Bis(2-mercaptoethyl)isophthalamide Binds Electrophilic Paracetamol Metabolites and Prevents Paracetamol-Induced Liver Toxicity.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Analgesics, Non-Narcotic; Animals; Antidotes; Benzene Derivatives; Benzoquinones; Chelating Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Imines; Mice; Sulfhydryl Compounds | 2018 |
N-acetyl cysteine alleviates oxidative stress and protects mice from dilated cardiomyopathy caused by mutations in nuclear A-type lamins gene.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiomyopathy, Dilated; Disease Models, Animal; Glutathione; Heart; Heart Failure; Heart Ventricles; Humans; Lamin Type A; Mice; Mutation; Myocardium; Oxidative Stress | 2018 |
N-acetylcysteine blocks serotonin 1B agonist-induced OCD-related behavior in mice.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Humans; Male; Mice; Obsessive-Compulsive Disorder; Receptor, Serotonin, 5-HT1B; Task Performance and Analysis | 2018 |
The gastroprotective effect of N-acetylcysteine and genistein in indomethacin-induced gastric injury in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Gastric Mucosa; Genistein; Humans; Indomethacin; Male; Matrix Metalloproteinase 9; Rats; Rats, Wistar; Stomach Ulcer | 2018 |
Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia.
Topics: Acetylcysteine; Action Potentials; Animals; Biotinylation; Capsaicin; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Erythromycin; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Inflammation; Male; Neurons; Patch-Clamp Techniques; Protein Kinase C-alpha; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Signal Transduction; TRPV Cation Channels | 2018 |
Effects of Topical Mucolytic Agents on the Tears and Ocular Surface: A Plausible Animal Model of Mucin-Deficient Dry Eye.
Topics: Acetylcysteine; Administration, Ophthalmic; Animals; Cell Count; Conjunctiva; Cornea; Disease Models, Animal; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Expectorants; Goblet Cells; Male; Microscopy, Electron, Scanning; Mucin 5AC; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Tears | 2018 |
N-acetylcysteine suppresses colistimethate sodium-induced nephrotoxicity via activation of SOD2, eNOS, and MMP3 protein expressions.
Topics: Acetylcysteine; Acetylglucosaminidase; Acute Kidney Injury; Animals; Colistin; Creatinine; Disease Models, Animal; Free Radical Scavengers; Humans; Kidney; Male; Matrix Metalloproteinase 3; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2018 |
Protective antioxidant effects of N-acetylcysteine against impairment of spermatogenesis caused by paranonylphenol.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Disease Models, Animal; Endocrine Disruptors; Environmental Pollutants; Male; Malondialdehyde; Mice; Oxidative Stress; Phenols; Seminiferous Tubules; Sperm Count; Sperm Motility; Spermatogenesis; Testosterone | 2018 |
Effects of N-acetylcysteine on arterial neo-intimal hyperplasia in rat model of arteriovenous fistula.
Topics: Acetylcysteine; Animals; Arteriovenous Shunt, Surgical; Disease Models, Animal; Femoral Artery; Femoral Vein; Graft Occlusion, Vascular; Hyperplasia; Male; Neointima; Rats; Time Factors; Vascular Patency | 2019 |
An Improved Inhaled Mucolytic to Treat Airway Muco-obstructive Diseases.
Topics: Acetylcysteine; Animals; Asthma; Cystic Fibrosis; Disease Models, Animal; Dithiothreitol; Expectorants; Humans; In Vitro Techniques; Male; Mice; Mucociliary Clearance; Mucus; Pulmonary Disease, Chronic Obstructive | 2019 |
The histone deacetylase inhibitor nicotinamide exacerbates neurodegeneration in the lactacystin rat model of Parkinson's disease.
Topics: Acetylation; Acetylcysteine; Animals; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Histone Deacetylase Inhibitors; Male; Nerve Degeneration; Niacinamide; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley | 2019 |
The effect of oral N-acetylcystein on prevention of extensive tissue destruction in electrical burn injury.
Topics: Acetylcysteine; Animals; Antioxidants; Burns, Electric; Creatine Kinase; Disease Models, Animal; Male; Necrosis; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Rhabdomyolysis; Skin; Wound Healing | 2018 |
N-Acetylcysteine potentiates the haemodynamic-improving effect of sildenafil in a rabbit model of acute pulmonary thromboembolism via the p38 MAPK pathway.
Topics: Acetylcysteine; Acute Disease; Animals; Apoptosis; Cell Count; Chemokine CCL2; Disease Models, Animal; Drug Synergism; Endothelial Cells; Hemodynamics; Lipid Peroxidation; Lung; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neutrophils; Nitric Oxide; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pulmonary Embolism; Rabbits; Sildenafil Citrate | 2019 |
N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E
Topics: Acetylcysteine; Animals; Arachidonate 5-Lipoxygenase; Cation Transport Proteins; Cell Nucleus; Cells, Cultured; Cerebral Hemorrhage; Collagenases; Cytoplasm; Dinoprostone; Disease Models, Animal; Eicosanoids; Female; Free Radical Scavengers; Glutathione; Hemin; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Stroke; Treatment Outcome | 2018 |
Skeletal Muscle Cell Oxidative Stress as a Possible Therapeutic Target in a Denervation-Induced Experimental Sarcopenic Model.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Line; Denervation; Disease Models, Animal; Hydrogen Peroxide; Male; Mitogen-Activated Protein Kinases; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sarcopenia; Sciatic Nerve | 2019 |
Serum and Tissue HIF-2 Alpha Expression in CIN, N-Acetyl Cysteine, and Sildenafil-Treated Rat Models: An Experimental Study.
Topics: Acetylcysteine; Animals; Contrast Media; Disease Models, Animal; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Diseases; Phosphodiesterase 5 Inhibitors; Rats; Rats, Wistar; Sildenafil Citrate | 2018 |
APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Apoptosis; Bone and Bones; Bone Resorption; Brain; Cells, Cultured; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Osteoblasts; Osteogenesis; Oxidative Stress; Reactive Oxygen Species | 2018 |
SAH-Induced Electrophysiological Changes of Ventricular Myocytes and Role of N-acetylcysteine Protection.
Topics: Acetylcysteine; Action Potentials; Animals; Calcium Channels; Disease Models, Animal; Free Radical Scavengers; Heart Ventricles; Male; Myocytes, Cardiac; Rabbits; Sodium Channels; Subarachnoid Hemorrhage | 2019 |
Interplay of N acetyl cysteine and melatonin in regulating oxidative stress-induced cardiac hypertrophic factors and microRNAs.
Topics: Acetylcysteine; Animals; Cardiomegaly; Cell Line; Disease Models, Animal; Free Radical Scavengers; Gene Expression Regulation; Melatonin; MicroRNAs; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2019 |
Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Disease Models, Animal; Energy Metabolism; Folic Acid; Glutathione; Humans; Mitochondria; Mitochondrial Dynamics; Oxidative Stress; Protein Processing, Post-Translational; Rats | 2019 |
Effect of NAC treatment and physical activity on neuroinflammation in subchronic Parkinsonism; is physical activity essential?
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcysteine; Analysis of Variance; Animals; Calcium-Binding Proteins; Disease Models, Animal; Encephalitis; Glial Fibrillary Acidic Protein; Imaging, Three-Dimensional; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microscopy, Confocal; Neuroprostanes; Parkinsonian Disorders; Physical Conditioning, Animal; S100 Calcium Binding Protein beta Subunit; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase | 2018 |
Effects of nebulized N--acetylcystein on the expression of HMGB1 and RAGE in rats with hyperoxia--induced lung injury.
Topics: Acetylcysteine; Animals; Animals, Newborn; Disease Models, Animal; Gene Expression Regulation; HMGB1 Protein; Humans; Hyperoxia; Lung; Lung Injury; Nebulizers and Vaporizers; NF-kappa B; Rats; Receptor for Advanced Glycation End Products; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
N-Acetylcysteine protects against intrauterine growth retardation-induced intestinal injury via restoring redox status and mitochondrial function in neonatal piglets.
Topics: Acetylcysteine; Animals; Animals, Newborn; Disease Models, Animal; DNA, Mitochondrial; Fetal Growth Retardation; Intestinal Diseases; Intestines; Oxidation-Reduction; Swine | 2019 |
N-acetylcysteine amide provides neuroprotection via Nrf2-ARE pathway in a mouse model of traumatic brain injury.
Topics: Acetylcysteine; Animals; Antioxidant Response Elements; Antioxidants; Apoptosis; Behavior, Animal; Brain; Brain Injuries, Traumatic; Caspase 3; Disease Models, Animal; Heme Oxygenase-1; Male; Membrane Proteins; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); Nerve Degeneration; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Time Factors | 2018 |
N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling.
Topics: Acetylcysteine; Animals; Antiviral Agents; Disease Models, Animal; Glioblastoma; Humans; Mice; Receptor, Notch2; Signal Transduction; Transfection | 2019 |
Activation of Sirtuin 3 and Maintenance of Mitochondrial Integrity by
Topics: Acetylcysteine; Animals; Apoptosis; Benzhydryl Compounds; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Male; Mitochondria; Mitochondrial Dynamics; Oxidative Stress; Phenols; Rats; Rats, Wistar; Signal Transduction; Sirtuins; Superoxide Dismutase | 2019 |
Regulation of HMGB1 release protects chemoradiotherapy-associated mucositis.
Topics: Acetylcysteine; Animals; Chemoradiotherapy; Disease Models, Animal; Female; Histones; HMGB1 Protein; Humans; Mice; Mouth Mucosa; Mucositis; Neoplasms; NF-kappa B; Organic Chemicals; Protective Agents; Protein Transport; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2019 |
Comparative analysis of thymic subpopulations during different modes of atrophy identifies the reactive oxygen species scavenger, N-acetyl cysteine, to increase the survival of thymocytes during infection-induced and lipopolysaccharide-induced thymic atro
Topics: Acetylcysteine; Animals; Atrophy; Cell Differentiation; Cell Survival; Disease Models, Animal; Free Radical Scavengers; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Salmonella Infections; Salmonella typhimurium; T-Lymphocytes; Thymocytes; Thymus Gland | 2019 |
Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway.
Topics: Acetylcysteine; Animals; Apoptosis; Arginine Vasopressin; Diabetes Insipidus, Neurogenic; Disease Models, Animal; Endoplasmic Reticulum Stress; Hypothalamus; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Random Allocation; Rats, Sprague-Dawley | 2019 |
Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Glaucoma; Humans; Mice; Retinal Degeneration | 2019 |
N-acetylcysteine yields sex-specific efficacy for cue-induced reinstatement of nicotine seeking.
Topics: Acetylcysteine; Animals; Craving; Cues; Disease Models, Animal; Drug-Seeking Behavior; Estrous Cycle; Extinction, Psychological; Female; Free Radical Scavengers; Male; Nicotine; Rats; Rats, Sprague-Dawley; Sex Factors; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2020 |
Sustained release of N-acetylcysteine by sandwich structured polycaprolactone/collagen scaffolds for wound healing.
Topics: Acetylcysteine; Animals; Biocompatible Materials; Cell Movement; Collagen; Delayed-Action Preparations; Disease Models, Animal; Mice; NIH 3T3 Cells; Platelet Endothelial Cell Adhesion Molecule-1; Polyesters; Prosthesis Implantation; Rats, Sprague-Dawley; Tensile Strength; Time Factors; Tissue Scaffolds; Wound Healing | 2019 |
N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat.
Topics: Acetylcysteine; Animals; Antidepressive Agents; Behavior, Animal; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Fluoxetine; Hippocampus; Inflammation; Male; Neuroimmunomodulation; Rats; Rats, Wistar; Serotonin; Stress, Physiological; Stress, Psychological | 2019 |
VEGF-A promotes angiogenesis after acute myocardial infarction through increasing ROS production and enhancing ER stress-mediated autophagy.
Topics: Acetylcysteine; Animals; Autophagy; Beclin-1; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Myocardial Infarction; Myocardial Ischemia; Neovascularization, Physiologic; Reactive Oxygen Species; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2019 |
Recombinant Human Superoxide Dismutase and
Topics: Acetylcysteine; Animals; Apoptosis; Biomarkers; Disease Models, Animal; Humans; Lung; Lung Compliance; Meconium Aspiration Syndrome; Oxidation-Reduction; Oxidative Stress; Rabbits; Reactive Oxygen Species; Recombinant Proteins; Respiratory Function Tests; Superoxide Dismutase; Surface-Active Agents | 2019 |
Drug repurposing of N-acetyl cysteine as antiviral against dengue virus infection.
Topics: Acetylcysteine; Animals; Antiviral Agents; Dengue; Dengue Virus; Disease Models, Animal; Drug Repositioning; Hep G2 Cells; Hepatocytes; Humans; Interferons; Liver; Mice; Oxidative Stress; Virus Replication | 2019 |
Withdrawal effects following repeated ethanol exposure are prevented by N-acetylcysteine in zebrafish.
Topics: Acetylcysteine; Animals; Anxiety; Brain; Catalase; Disease Models, Animal; Ethanol; Female; Lipid Peroxidation; Male; Oxidative Stress; Substance Withdrawal Syndrome; Superoxide Dismutase; Zebrafish | 2019 |
Postnatal N-acetylcysteine administration rescues impaired social behaviors and neurogenesis in Slc13a4 haploinsufficient mice.
Topics: Acetylcysteine; Animals; Animals, Newborn; Behavior, Animal; Brain; Disease Models, Animal; Female; Gene Expression; Genotype; Haploinsufficiency; Male; Maze Learning; Memory; Mice; Mice, Transgenic; Neurogenesis; Phenotype; Social Behavior; Sulfate Transporters; Symporters | 2019 |
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; Cisplatin; Complement C5a; Disease Models, Animal; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Neutrophils; Oxidative Stress; Receptor, Anaphylatoxin C5a | 2019 |
Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.
Topics: Acetylcysteine; Animals; Astrocytes; Biomarkers; Case-Control Studies; Cell Count; Cognitive Dysfunction; Disease Models, Animal; Electric Stimulation; Epilepsy; Glutathione; Hippocampus; HMGB1 Protein; Humans; Isothiocyanates; Male; Neurons; Oxidative Stress; Rats; Status Epilepticus; Sulfoxides | 2019 |
N-acetylcysteine prevents bladder tissue fibrosis in a lipopolysaccharide-induced cystitis rat model.
Topics: Acetylcysteine; Animals; CARD Signaling Adaptor Proteins; Chemokine CXCL10; Cystitis; Disease Models, Animal; Female; Fibrosis; Gene Expression Profiling; Inflammation; Lipopolysaccharides; Protamines; Rats; Rats, Sprague-Dawley; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Urinary Bladder | 2019 |
N-acetyl cysteine, inulin and the two as a combined therapy ameliorate cognitive decline in testosterone-deprived rats.
Topics: Acetylcysteine; Animals; Apoptosis; Astrocytes; Blood-Brain Barrier; Brain; Castration; Cognition; Cognitive Dysfunction; Disease Models, Animal; Drug Therapy, Combination; Dysbiosis; Hippocampus; Inflammation; Inulin; Male; Malondialdehyde; Microglia; Motor Activity; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Testosterone | 2019 |
Gene Expression Signatures Associated With Survival Times of Pediatric Patients With Biliary Atresia Identify Potential Therapeutic Agents.
Topics: Acetylcysteine; Age Factors; Animals; Biliary Atresia; Case-Control Studies; Child, Preschool; Disease Models, Animal; Female; Gene Expression Profiling; Gene Regulatory Networks; Genetic Markers; Genetic Predisposition to Disease; Humans; Infant; Liver Transplantation; Male; Mice, Inbred BALB C; Phenotype; Predictive Value of Tests; Progression-Free Survival; Risk Assessment; Risk Factors; RNA, Messenger; Time Factors; Transcriptome; Treatment Outcome | 2019 |
TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model.
Topics: Acetylcysteine; Adolescent; alpha-Tocopherol; Amino Acid Motifs; Amino Acid Sequence; Animals; Animals, Genetically Modified; Antioxidants; Biological Transport; Catalytic Domain; Child; Child, Preschool; Crystallography, X-Ray; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Dystonia; Epilepsy, Rolandic; Female; GTPase-Activating Proteins; Humans; Infant; Locomotion; Male; Models, Molecular; Mutation, Missense; Neurons; Oxidative Stress; Pedigree; Physical Exertion; Protein Conformation; rab GTP-Binding Proteins; Reactive Oxygen Species; Recombinant Proteins; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid; Synaptic Vesicles | 2019 |
N-acetylcysteine tiherapeutically protects against pulmonary fibrosis in a mouse model of silicosis.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Crystallization; Disease Models, Animal; Female; Gene Expression Regulation; Glutathione Peroxidase; Interleukin-1beta; Interleukin-4; Interleukin-6; Lung; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Fibrosis; Reactive Oxygen Species; Silicon Dioxide; Silicosis; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 2019 |
N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse.
Topics: Acetylcysteine; Acute Disease; Alcohol-Related Disorders; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Ethanol; Free Radical Scavengers; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Psychological | 2020 |
Accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine-seeking behavior.
Topics: Acetylcysteine; Animals; Astrocytes; Conditioning, Psychological; Disease Models, Animal; Drug-Seeking Behavior; Glial Fibrillary Acidic Protein; Glutamic Acid; Male; Nicotine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Signal Transduction; Tumor Necrosis Factor-alpha | 2020 |
Additional effects of erythropoietin pretreatment, ischemic preconditioning, and N-acetylcysteine posttreatment in rat kidney reperfusion injury
Topics: Acetylcysteine; Animals; Blood Urea Nitrogen; Creatinine; Cytokines; Disease Models, Animal; Erythropoietin; Ischemic Preconditioning; Kidney; Kidney Diseases; Male; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury | 2019 |
Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cobamides; Cyclic GMP-Dependent Protein Kinase Type I; Disease Models, Animal; Echocardiography; Female; Free Radical Scavengers; Gain of Function Mutation; Gene Knock-In Techniques; HEK293 Cells; Humans; Male; Marfan Syndrome; Mice; Mice, Transgenic; Myocytes, Smooth Muscle; Oxidative Stress; Primary Cell Culture | 2019 |
Inhibition of endotoxin-induced perinatal asthma protection by pollutants in an experimental mouse model.
Topics: Acetylation; Acetylcysteine; Air Pollutants; Allergens; Animals; Antibodies, Blocking; Antibodies, Monoclonal; Antioxidants; Asthma; Disease Models, Animal; Endotoxins; Epigenesis, Genetic; Female; Histones; Interferon-gamma; Lipopolysaccharides; Maternal Exposure; Mice; Mycotoxins; Ovalbumin; Pregnancy; Prenatal Exposure Delayed Effects; Promoter Regions, Genetic | 2013 |
High dose intracoronary N-acetylcysteine in a porcine model of ST-elevation myocardial infarction.
Topics: Acetylcysteine; Animals; Contrast Media; Coronary Angiography; Disease Models, Animal; Female; Free Radical Scavengers; Iopamidol; Myocardial Infarction; Myocardial Reperfusion Injury; Swine | 2013 |
Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.
Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Colonic Neoplasms; Disease Models, Animal; Drinking Water; Eating; Feces; Heme; Lipid Peroxidation; Male; Meat; Nitrites; Nitroso Compounds; Rats, Inbred F344; Saliva; Sodium Nitrite; Thiobarbituric Acid Reactive Substances | 2013 |
N-acetylcysteine attenuates subcutaneous administration of bleomycin-induced skin fibrosis and oxidative stress in a mouse model of scleroderma.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Bleomycin; Catalase; Disease Models, Animal; Female; Fibrosis; Free Radical Scavengers; Injections, Subcutaneous; Malondialdehyde; Mice; Mice, Inbred BALB C; Oxidative Stress; Reactive Oxygen Species; Scleroderma, Localized; Skin; Superoxide Dismutase; Thiobarbiturates | 2013 |
Protective and therapeutic potency of N-acetyl-cysteine on propionic acid-induced biochemical autistic features in rats.
Topics: Acetylcysteine; Analysis of Variance; Animals; Autistic Disorder; Brain; Comet Assay; Disease Models, Animal; DNA; Gene Expression Regulation; Glutathione Transferase; Interferon-gamma; Male; Neuroprotective Agents; Propionates; Rats; ROC Curve; Serotonin | 2013 |
N-acetyl-L-cysteine protects against inhaled sulfur mustard poisoning in the large swine.
Topics: Acetylcysteine; Administration, Inhalation; Aerosols; Animals; Antidotes; Antioxidants; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Disease Models, Animal; Expectorants; Female; Gas Poisoning; Lung; Lung Diseases; Mustard Gas; Neutrophil Infiltration; Random Allocation; Respiratory Insufficiency; Survival Analysis; Sus scrofa | 2013 |
Direct intranigral administration of an ubiquitin proteasome system inhibitor in rat: behavior, positron emission tomography, immunohistochemistry.
Topics: Acetylcysteine; Analysis of Variance; Animals; Carbon Isotopes; Cell Count; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Hindlimb; Locomotion; Movement Disorders; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tetrabenazine; Time Factors; Tyrosine 3-Monooxygenase | 2013 |
Effect of N-acetyl cysteine (NAC), an organosulfur compound from Allium plants, on experimentally induced hepatic prefibrogenic events in Wistar rat.
Topics: Acetylcysteine; Allium; Animals; Carbon Tetrachloride; Disease Models, Animal; Liver Cirrhosis; Male; Oxidative Stress; Phytotherapy; Rats; Rats, Wistar; Sulfur; Thioacetamide | 2013 |
The oxidative stress induced in vivo by Shiga toxin-2 contributes to the pathogenicity of haemolytic uraemic syndrome.
Topics: Acetylcysteine; Animals; Cysteine; Disease Models, Animal; Glutathione; Hemolytic-Uremic Syndrome; Lipid Peroxidation; Male; Malondialdehyde; Mice; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Shiga Toxin 2; Shiga-Toxigenic Escherichia coli | 2013 |
Activating mutations in protein tyrosine phosphatase Ptpn11 (Shp2) enhance reactive oxygen species production that contributes to myeloproliferative disorder.
Topics: Acetylcysteine; Animals; Bone Marrow Cells; Cell Differentiation; Cytokines; Disease Models, Animal; Hematopoietic Stem Cells; Mice; Mice, Knockout; Mitochondria; Mutation; Myeloid Cells; Myeloproliferative Disorders; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Reactive Oxygen Species; Signal Transduction | 2013 |
Determination of urine 3-HPMA, a stable acrolein metabolite in a rat model of spinal cord injury.
Topics: Acetylcysteine; Acrolein; Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Immunoblotting; Male; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tandem Mass Spectrometry | 2013 |
N-acetylcysteine reverses cardiac myocyte dysfunction in a rodent model of behavioral stress.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cardiomyopathies; Catalase; Disease Models, Animal; Epinephrine; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Isoproterenol; Male; Myocardium; Myocytes, Cardiac; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2013 |
Influence of N-acetylcysteine on Klotho expression and its signaling pathway in experimental model of chronic cyclosporine nephropathy in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Glucuronidase; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Superoxide Dismutase | 2013 |
Dietary N-acetylcysteine supplementation alleviates liver injury in lipopolysaccharide-challenged piglets.
Topics: Acetylcysteine; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytokines; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Female; HSP70 Heat-Shock Proteins; Inflammation Mediators; Lipopolysaccharides; Liver; NF-kappa B; Random Allocation; Swine | 2014 |
Adjunctive N-acetyl-L-cysteine in treatment of murine pneumococcal meningitis.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Ceftriaxone; Cochlea; Disease Models, Animal; Hearing Loss; Male; Meningitis, Pneumococcal; Mice; Mice, Inbred C57BL | 2013 |
Effects of amifostine on endometriosis, comparison with N-acetyl cysteine, and leuprolide as a new treatment alternative: a randomized controlled trial.
Topics: Abdominal Wall; Acetylcysteine; Amifostine; Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Leuprolide; Peritoneal Diseases; Peritoneum; Random Allocation; Rats; Rats, Wistar; Treatment Outcome | 2014 |
Treatment with the cysteine precursor l-2-oxothiazolidine-4-carboxylate (OTC) implicates taurine deficiency in severity of dystropathology in mdx mice.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Muscular Dystrophy, Duchenne; Oxidative Stress; Pyrrolidonecarboxylic Acid; Taurine; Thiazolidines | 2013 |
The story of glutamate in drug addiction and of N-acetylcysteine as a potential pharmacotherapy.
Topics: Acetylcysteine; Animals; Brain; Clinical Trials as Topic; Disease Models, Animal; Glutamic Acid; Receptors, Glutamate; Substance-Related Disorders | 2013 |
Hyperbaric oxygen treatment and N-acetylcysteine ameliorate acetaminophen-induced liver injury in a rat model.
Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hyperbaric Oxygenation; Interleukin-6; Liver; Male; Neopterin; Protective Agents; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2013 |
Protective effects of N-acetylcysteine on acetic acid-induced colitis in a porcine model.
Topics: Acetic Acid; Acetylcysteine; Amphiregulin; Animals; Apoptosis; Caspase 3; Claudin-1; Colitis; Colitis, Ulcerative; Colon; Dietary Supplements; Dinoprostone; Disease Models, Animal; EGF Family of Proteins; Epidermal Growth Factor; ErbB Receptors; Free Radical Scavengers; Glycoproteins; Intercellular Signaling Peptides and Proteins; Interleukin-6; Intestinal Mucosa; Swine; Toll-Like Receptor 4; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha | 2013 |
Efficacy of two FDA-approved drug combination in a mouse model of staphylococcal enterotoxin B-induced shock.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Chemokine CCL2; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Enterotoxins; Female; Free Radical Scavengers; Interferon-gamma; Interleukin-2; Interleukin-6; Lung; Male; Mice; Shock, Septic | 2013 |
Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury.
Topics: Acetylcysteine; Animals; Avoidance Learning; Brain Injuries; Cognition Disorders; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Inflammation; Memory Disorders; Minocycline; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2013 |
N-acetyl-L-cysteine prevents stress-induced desmin aggregation in cellular models of desminopathy.
Topics: Acetylcysteine; Animals; Cardiomyopathies; Cell Line; Codon; Cytoskeleton; Desmin; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Expression; Heat-Shock Proteins; Humans; Mice; Muscular Dystrophies; Mutation; Protein Binding; Stress, Physiological | 2013 |
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
Topics: Acetylcysteine; Activating Transcription Factor 6; Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; eIF-2 Kinase; Endoplasmic Reticulum Stress; Free Radical Scavengers; Gene Knockdown Techniques; Glucose; Membrane Proteins; Myocytes, Cardiac; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2013 |
Protective effects of L-carnitine, N-acetylcysteine and genistein in an experimental model of liver fibrosis.
Topics: Acetylcysteine; Animals; Carnitine; Disease Models, Animal; Genistein; Liver Cirrhosis; Male; Rats; Rats, Wistar | 2014 |
Effects of N-acetylcysteine in ozone-induced chronic obstructive pulmonary disease model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Apoptosis; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Deoxyguanosine; Disease Models, Animal; Emphysema; Expectorants; Gene Expression; Lung; Malondialdehyde; Mice; Ozone; Pulmonary Disease, Chronic Obstructive; Respiratory Function Tests | 2013 |
An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antibodies, Monoclonal; Calcium-Binding Proteins; Cell Count; Choline O-Acetyltransferase; Cholinergic Neurons; Cysteine Proteinase Inhibitors; Disease Models, Animal; Forelimb; Functional Laterality; Image Processing, Computer-Assisted; Laser Capture Microdissection; Magnetic Resonance Imaging; Male; Membrane Proteins; Motor Activity; Muscle Proteins; Nerve Degeneration; Parkinson Disease; Pedunculopontine Tegmental Nucleus; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2015 |
Hypoxia-inducible factor 1 contributes to N-acetylcysteine's protection in stroke.
Topics: Acetylcysteine; Animals; Brain Ischemia; Disease Models, Animal; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Rats; Reperfusion Injury; Signal Transduction; Stroke | 2014 |
N-acetylcysteine improves cardiac contractility and ameliorates myocardial injury in a rat model of lung ischemia and reperfusion injury.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Bronchoalveolar Lavage Fluid; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Hydroxyl Radical; Lipid Peroxidation; Lung; Lung Injury; Male; Myocardial Contraction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Troponin I; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure | 2013 |
The effects of L-carnitine and N-acetylcysteine on carbontetrachloride induced acute liver damage in rats.
Topics: Acetylcysteine; Animals; Carbon Tetrachloride; Carnitine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Free Radical Scavengers; Liver; Oxidative Stress; Rats; Rats, Wistar; Vitamin B Complex | 2013 |
Effects of histidine and N-acetylcysteine on doxorubicin-induced cardiomyopathy in rats.
Topics: Acetylcysteine; Animals; Biomarkers; Cardiomyopathies; Creatine Kinase; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Electrocardiography; Free Radical Scavengers; Heart Rate; Histidine; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardium; Rats, Wistar; Recovery of Function | 2014 |
Cardioprotection during diabetes: the role of mitochondrial DNA.
Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA, Mitochondrial; Free Radical Scavengers; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Reactive Oxygen Species | 2014 |
N-acetylcysteine supplementation decreases osteoclast differentiation and increases bone mass in mice fed a high-fat diet.
Topics: Acetylcysteine; Animals; Antioxidants; Body Weight; Bone Density; Bone Resorption; Cell Differentiation; Cell Line, Tumor; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Glutathione; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Osteoclasts | 2014 |
[Effects of N-acetylcysteine on apoptosis induced by myocardial ischemia reperfusion injury in rats' heart transplantation].
Topics: Acetylcysteine; Animals; Apoptosis; Caspase 3; Disease Models, Animal; Graft Survival; Heart Transplantation; Immunohistochemistry; Injections, Intravenous; Ischemic Preconditioning; Male; Myocardium; Protective Agents; Random Allocation; Rats; Rats, Inbred Lew; Reperfusion Injury; Superoxide Dismutase | 2013 |
Antioxidants accelerate lung cancer progression in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; DNA Damage; Fibroblasts; Humans; Lung Neoplasms; Mice; Reactive Oxygen Species; Solubility; Tumor Suppressor Protein p53; Vitamin E | 2014 |
Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra.
Topics: Acetylcysteine; Action Potentials; Animals; Dicarboxylic Acids; Disease Models, Animal; Exploratory Behavior; Forelimb; Free Radical Scavengers; Functional Laterality; Glutamate Decarboxylase; Glutamate Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Motor Activity; Neuroglia; Neurotransmitter Uptake Inhibitors; Parkinsonian Disorders; Pyrrolidines; Rats; Rats, Wistar; Substantia Nigra; Thiobarbituric Acid Reactive Substances; Tyrosine 3-Monooxygenase | 2014 |
Dendrimer brain uptake and targeted therapy for brain injury in a large animal model of hypothermic circulatory arrest.
Topics: Acetylcysteine; Animals; Biological Transport; Brain; Brain Injuries; Circulatory Arrest, Deep Hypothermia Induced; Dendrimers; Disease Models, Animal; Dogs; Drug Carriers; Male; Microglia; Nanomedicine; Neurons; Rabbits; Treatment Outcome; Valproic Acid | 2014 |
The effects of remote ischemic preconditioning and N-acetylcysteine with remote ischemic preconditioning in rat hepatic ischemia reperfusion injury model.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Ischemic Preconditioning; Liver; Male; Rats; Rats, Wistar; Reperfusion Injury | 2014 |
[High-fat diet induces pulmonary fibrosis in rats and inhibitory effects of N-acetylcysteine].
Topics: Acetylcysteine; Animals; Diet, High-Fat; Disease Models, Animal; Lung; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2013 |
N-acetylcysteine modulates hallucinogenic 5-HT(2A) receptor agonist-mediated responses: behavioral, molecular, and electrophysiological studies.
Topics: Acetylcysteine; Action Potentials; Amino Acids; Amphetamines; Animals; Benzoates; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Early Growth Response Protein 2; Excitatory Amino Acid Antagonists; Free Radical Scavengers; GABA-A Receptor Antagonists; Glycine; Hallucinations; Hallucinogens; Male; Mice; Proto-Oncogene Proteins c-fos; Receptors, Metabotropic Glutamate; Xanthenes | 2014 |
The effects of N-acetylcysteine on cocaine reward and seeking behaviors in a rat model of depression.
Topics: Acetylcysteine; Animals; Cocaine; Conditioning, Operant; Depression; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Male; Motor Activity; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration | 2014 |
The effects of sildenafil and n-acetylcysteine on ischemia and reperfusion injury in gastrocnemius muscle and femoral artery endothelium.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Cytoprotection; Disease Models, Animal; Endothelium, Vascular; Femoral Artery; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Peroxidation; Malondialdehyde; Muscle, Skeletal; Oxidative Stress; Piperazines; Purines; Rats, Sprague-Dawley; Reperfusion Injury; Sildenafil Citrate; Sulfonamides; Time Factors; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2015 |
Novel nanosome delivery system combined with siRNA targeting the antimicrobial gene DFB4: a new approach for psoriasis management?
Topics: Acetylcysteine; Animals; beta-Defensins; Disease Models, Animal; Drug Delivery Systems; Epidermis; Gene Silencing; Humans; Mice; Nanomedicine; Nanoparticles; Phenotype; Psoriasis; RNA, Small Interfering; Skin Transplantation | 2014 |
The effects of N-acetyl-cysteine and acetyl-L-carnitine on neural survival, neuroinflammation and regeneration following spinal cord injury.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Axons; Cell Survival; Cervical Vertebrae; Disease Models, Animal; Female; Microglia; Motor Neurons; Nerve Regeneration; Neuroimmunomodulation; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2014 |
Neuroprotective effect of N-acetyl cysteine against streptozotocin-induced memory dysfunction and oxidative damage in rats.
Topics: Acetylcysteine; Animals; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Memory Disorders; Mitochondria; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Streptozocin | 2015 |
High uric acid directly inhibits insulin signalling and induces insulin resistance.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glucose Intolerance; Hep G2 Cells; Humans; Hyperuricemia; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Uric Acid | 2014 |
Inhibitory effect of N-acetyl cysteine and ascorbic acid on the development of myringosclerosis: an experimental study.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Female; Fibrin Foam; Fibroblasts; Free Radical Scavengers; Guinea Pigs; Hemostatics; Immunohistochemistry; Inflammation; Leukocytes; Microscopy; Mucous Membrane; Myringosclerosis; Nitric Oxide Synthase; Random Allocation; Transforming Growth Factor beta; Tympanic Membrane; Vascular Endothelial Growth Factor A | 2014 |
Determination of DNA damage in experimental liver intoxication and role of N-acetyl cysteine.
Topics: Acetylation; Acetylcysteine; Animals; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA Damage; Histone Acetyltransferases; Histone Deacetylases; Histones; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2014 |
Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.
Topics: Acetylcysteine; Analysis of Variance; Animals; Carrier Proteins; Caspase 1; Conjunctiva; Cornea; Disease Models, Animal; Disease Progression; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Female; Free Radical Scavengers; Inflammasomes; Interleukin-1beta; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction | 2014 |
Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker.
Topics: Acetylcysteine; Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Disease Models, Animal; Diuretics; Free Radical Scavengers; Furosemide; Iohexol; Ioxaglic Acid; Kidney; Lipocalin-2; Lipocalins; Magnetic Resonance Imaging; Male; Oxygen; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Triiodobenzoic Acids | 2014 |
N-acetylcysteine reduces oxidative stress, nuclear factor‑κB activity and cardiomyocyte apoptosis in heart failure.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Dinoprost; Disease Models, Animal; Glutathione; Heart Failure; Hemodynamics; I-kappa B Proteins; Myocardium; Myocytes, Cardiac; NF-KappaB Inhibitor alpha; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rabbits; Transcription Factor RelA | 2014 |
Impact of N-Acetylcysteine on cerebral amyloid-β plaques and kidney damage in spontaneously hypertensive stroke-prone rats.
Topics: Acetylcysteine; Amyloid beta-Peptides; Analysis of Variance; Animals; Blood-Brain Barrier; Cerebral Cortex; Cerebral Small Vessel Diseases; Disease Models, Animal; Fibronectins; Free Radical Scavengers; Kidney Diseases; Lectins; Male; Plaque, Amyloid; Platelet Membrane Glycoproteins; Rats; Rats, Inbred SHR | 2014 |
N-Acetylcysteine increases corneal endothelial cell survival in a mouse model of Fuchs endothelial corneal dystrophy.
Topics: Acetylcysteine; Animals; Blotting, Western; Cell Count; Cell Survival; Cells, Cultured; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endothelium, Corneal; Free Radical Scavengers; Fuchs' Endothelial Dystrophy; Heat-Shock Proteins; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Nitric Oxide Synthase Type II; Oxidative Stress; Polymerase Chain Reaction; RNA, Messenger; Thapsigargin; Transcription Factor CHOP | 2014 |
N-acetyl-l-cystine (NAC) protects against H9N2 swine influenza virus-induced acute lung injury.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Antioxidants; Cytokines; Disease Models, Animal; Humans; Inflammation Mediators; Influenza A Virus, H9N2 Subtype; Influenza, Human; Lipid A; Lung; Male; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Peroxidase; Swine; Toll-Like Receptor 4; Virus Replication | 2014 |
A high-throughput model of post-traumatic osteoarthritis using engineered cartilage tissue analogs.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Cartilage, Articular; Caspase Inhibitors; Cattle; Cell Death; Disease Models, Animal; Drug Evaluation, Preclinical; Glycosaminoglycans; High-Throughput Screening Assays; Materials Testing; Osteoarthritis; Pilot Projects; Poloxamer; Stress, Mechanical; Tissue Engineering | 2014 |
Oral warfarin and the thrombin inhibitor dabigatran increase blood pressure in rats: hidden danger of anticoagulants?
Topics: Acetylcysteine; Animals; Anticoagulants; Antifibrinolytic Agents; Antithrombins; Benzimidazoles; beta-Alanine; Blood Pressure; Dabigatran; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Nephrectomy; Pyrroles; Quinazolines; Rats; Receptor, PAR-1; Renal Insufficiency, Chronic; Vitamin K; Warfarin | 2015 |
Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats.
Topics: Acetylcysteine; Amifostine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Liver; Male; Methotrexate; Oxidative Stress; Rats, Sprague-Dawley; Time Factors | 2014 |
Intratracheal co-administration of antioxidants and ceftriaxone reduces pulmonary injury and mortality rate in an experimental model of sepsis.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Ceftriaxone; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Lung Injury; Male; Rats; Rats, Wistar; Sepsis; Trachea; Vitamin E | 2014 |
Juvenile antioxidant treatment prevents adult deficits in a developmental model of schizophrenia.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Dopamine Agonists; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; Hippocampus; Ibotenic Acid; In Vitro Techniques; Neurons; Pregnancy; Quinpirole; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia | 2014 |
Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Disease Models, Animal; Free Radical Scavengers; Interleukin-1beta; Lactate Dehydrogenases; Liver; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Neostigmine; Tumor Necrosis Factor-alpha | 2014 |
N-Acetylcysteine Ameliorates Experimental Autoimmune Myocarditis in Rats via Nitric Oxide.
Topics: Acetylcysteine; Animals; Autoimmune Diseases; Disease Models, Animal; Intercellular Adhesion Molecule-1; Myocarditis; Nitric Oxide; Rats; Rats, Inbred Lew; Superoxides | 2015 |
N-acetylcysteine administration confers lung protection in different phases of lung ischaemia-reperfusion injury.
Topics: Acetylcysteine; Administration, Intravenous; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Cytoprotection; Disease Models, Animal; Hemodynamics; I-kappa B Kinase; Inflammation Mediators; Interleukin-1beta; Lipid Peroxidation; Lung; Lung Injury; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
Effects of N-acetylcysteine and imipramine in a model of acute rhythm disruption in BALB/c mice.
Topics: Acetylcysteine; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Circadian Rhythm; Corticosterone; Depression; Disease Models, Animal; Imipramine; Interleukin-6; Light; Male; Mice; Mice, Inbred BALB C; Motor Activity; Photoperiod; Rest; Social Behavior; Temperature; Time Factors | 2015 |
Cardiovascular effects of N-acetylcysteine in meconium-induced acute lung injury.
Topics: Acetylcysteine; Acute Lung Injury; Aldosterone; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Heart Rate; Humans; Infant, Newborn; Injections, Intravenous; Intubation, Intratracheal; Lung; Meconium; Meconium Aspiration Syndrome; Oxidative Stress; Rabbits; Respiration, Artificial; Thiobarbituric Acid Reactive Substances | 2015 |
N-acetylcysteine alleviates the meconium-induced acute lung injury.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Humans; Infant, Newborn; Injections, Intravenous; Intubation, Intratracheal; Leukocyte Count; Lipid Peroxidation; Lung; Meconium; Meconium Aspiration Syndrome; Oxidative Stress; Pulmonary Edema; Rabbits; Respiration, Artificial; Thiobarbituric Acid Reactive Substances; Trachea | 2015 |
Impact of N-acetylcysteine and etodolac treatment on systolic and diastolic function in a rat model of myocardial steatosis induced by high-fat-diet.
Topics: Acetylcysteine; Animals; Cardiomyopathies; Diastole; Diet, High-Fat; Disease Models, Animal; Etodolac; Lipid Metabolism Disorders; Male; Rats; Rats, Sprague-Dawley; Systole | 2014 |
EAAC1 gene deletion increases neuronal death and blood brain barrier disruption after transient cerebral ischemia in female mice.
Topics: Acetylcysteine; Animals; Blood-Brain Barrier; Cell Death; Cysteine; Disease Models, Animal; Excitatory Amino Acid Transporter 3; Female; Gene Deletion; Glutathione; Ischemic Attack, Transient; Mice; Mice, Knockout; Neurons | 2014 |
Antioxidants inhibit the inflammatory and apoptotic processes in an intermittent hypoxia model of sleep apnea.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Caspases; Disease Models, Animal; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Liver; Male; Melatonin; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Sleep Apnea Syndromes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2015 |
N-acetylcysteine attenuates reactive-oxygen-species-mediated endoplasmic reticulum stress during liver ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cells, Cultured; Cytoprotection; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Liver; Liver Diseases; Male; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction | 2014 |
PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation.
Topics: Acetylation; Acetylcysteine; Animals; Benzamides; Cell Nucleus; Cytoplasm; Disease Models, Animal; Endotoxemia; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Histone Acetyltransferases; Histone Deacetylases; HMGB1 Protein; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Transport; Pyrazoles; Pyridazines; Reactive Oxygen Species | 2014 |
Free radical scavengers improve liver function but not morphological changes induced by reperfusion injury.
Topics: Acetylcysteine; Animals; Aspartate Aminotransferases; Chromans; Disease Models, Animal; Female; Free Radical Scavengers; Gentisates; L-Lactate Dehydrogenase; Liver; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Superoxides | 2015 |
N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Brain Neoplasms; Cells, Cultured; Child; Cisplatin; Disease Models, Animal; Female; Humans; Male; Medulloblastoma; Neoplasm Transplantation; Neoplasms, Experimental; Neuroblastoma; Oxidative Stress; Rats; Rats, Nude | 2015 |
In vivo optical imaging of matrix metalloproteinase activity detects acute and chronic contact hypersensitivity reactions and enables monitoring of the antiinflammatory effects of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Dermatitis, Allergic Contact; Disease Models, Animal; Ear; Female; Gene Expression Regulation; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Picryl Chloride | 2014 |
Role of cytochrome P450-mediated metabolism and identification of novel thiol-conjugated metabolites in mice with phenytoin-induced liver injury.
Topics: Acetylcysteine; Activation, Metabolic; Alanine Transaminase; Animals; Anticonvulsants; Bile; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Glutathione; Liver; Mice, Inbred C57BL; Phenytoin; Sulfhydryl Compounds; Time Factors | 2015 |
Effective inhibition of cardiomyocyte apoptosis through the combination of trimetazidine and N-acetylcysteine in a rat model of myocardial ischemia and reperfusion injury.
Topics: Acetylcysteine; Animals; Apoptosis; Blood Pressure; Caspase 3; Cell Death; Coronary Vessels; Disease Models, Animal; Fatty Acids; Glucose; Glutathione; Inflammation; Male; Malondialdehyde; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; S100 Calcium Binding Protein beta Subunit; Trimetazidine | 2014 |
N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury.
Topics: Acetylcysteine; Acute Lung Injury; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chlorine; Cytoprotection; Dexamethasone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Fibrinogen; Gases; Inhalation Exposure; Lung; Mice, Inbred BALB C; Neutrophil Infiltration; Plasminogen Activator Inhibitor 1; Time Factors | 2015 |
Attenuation of copaiba oil in hepatic damage in rats.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Corn Oil; Disease Models, Animal; Fabaceae; gamma-Glutamyltransferase; Male; Plant Oils; Random Allocation; Rats, Wistar; Treatment Outcome | 2014 |
I-FABP as biomarker for the early diagnosis of acute mesenteric ischemia and resultant lung injury.
Topics: Acetylcysteine; alpha-Defensins; Animals; Biomarkers; Disease Models, Animal; Early Diagnosis; Fatty Acid-Binding Proteins; Lung Injury; Male; Mesenteric Ischemia; Mice; Mice, Inbred C57BL | 2014 |
N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Free Radical Scavengers; Gait; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Organ Size; Oxidative Stress | 2015 |
Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration.
Topics: Acetylcysteine; Animals; Apoptosis; Choroid; Choroidal Neovascularization; Disease Models, Animal; Electroretinography; Humans; Macular Degeneration; Mice; Plasma Gases; Reactive Oxygen Species; Retina | 2015 |
N-acetylcysteine effectively diminished meconium-induced oxidative stress in adult rabbits.
Topics: Acetylcysteine; Age Factors; Animals; Antioxidants; Biomarkers; Disease Models, Animal; Humans; Infant, Newborn; Inflammation Mediators; Leukocytes; Lipid Peroxidation; Lung; Lung Injury; Meconium; Meconium Aspiration Syndrome; Mitochondria; Oxidative Stress; Pneumonia; Pulmonary Edema; Rabbits; Thiobarbituric Acid Reactive Substances; Time Factors | 2015 |
N-acetylcysteine prevents rotenone-induced Parkinson's disease in rat: An investigation into the interaction of parkin and Drp1 proteins.
Topics: Acetylcysteine; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drug Interactions; Dynamins; Male; Oxidative Stress; Parkinsonian Disorders; Protein Binding; Random Allocation; Rats; Rats, Wistar; Rotarod Performance Test; Rotenone; Substantia Nigra; Ubiquitin-Protein Ligases | 2015 |
N-acetylcysteine treatment following spinal cord trauma reduces neural tissue damage and improves locomotor function in mice.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Humans; Mice; Motor Activity; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Recovery of Function; Spinal Cord Injuries | 2015 |
The protective effect of N-acetylcysteine against acrylamide toxicity in liver and small and large intestine tissues.
Topics: Acetylcysteine; Acrylamide; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Free Radical Scavengers; Intestinal Diseases; Intestine, Large; Liver; Male; Rats; Rats, Wistar | 2015 |
Do Montelukast Sodium and N-Acetylcysteine Have a Nephroprotective Effect on Unilateral Ureteral Obstruction? A Placebo Controlled Trial in a Rat Model.
Topics: Acetates; Acetylcysteine; Animals; Cyclopropanes; Disease Models, Animal; Kidney Diseases; Male; Placebos; Quinolines; Randomized Controlled Trials as Topic; Rats; Rats, Wistar; Sulfides; Ureteral Obstruction | 2015 |
Activation and regulation of the granulation tissue derived cells with stemness-related properties.
Topics: Acetylcysteine; Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Dermis; Disease Models, Animal; Gene Knock-In Techniques; Granulation Tissue; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotides, Antisense; Reactive Oxygen Species; Skin Diseases; Stem Cell Transplantation; Stem Cells; Wound Healing | 2015 |
Melatonin prevents hyperglycemia in a model of sleep apnea.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; Free Radical Scavengers; Hyperglycemia; Hypoxia; Melatonin; Mice, Inbred BALB C; Sleep Apnea, Obstructive; Time Factors; Triglycerides | 2015 |
The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania.
Topics: Acetylcysteine; Aldehydes; Analysis of Variance; Animals; Antimanic Agents; Bipolar Disorder; Brain; Deferoxamine; Disease Models, Animal; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Sleep Deprivation; Tyrosine | 2015 |
The combination of N-acetyl cysteine, alpha-lipoic acid, and bromelain shows high anti-inflammatory properties in novel in vivo and in vitro models of endometriosis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Apoptosis; Bromelains; Cells, Cultured; Disease Models, Animal; Endometriosis; Endothelial Cells; Female; Humans; Inflammation; Mice; Mice, SCID; Microscopy, Fluorescence; Thioctic Acid; Tumor Necrosis Factor-alpha; Uterus; Vascular Cell Adhesion Molecule-1 | 2015 |
N-acetyl cysteine and mushroom Agaricus sylvaticus supplementation decreased parasitaemia and pulmonary oxidative stress in a mice model of malaria.
Topics: Acetylcysteine; Agaricus; Animals; Dietary Supplements; Disease Models, Animal; Lung; Malaria; Male; Mice; Oxidative Stress; Parasitemia; Plasmodium berghei | 2015 |
Pedunculopontine cell loss and protein aggregation direct microglia activation in parkinsonian rats.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Cell Count; Choline O-Acetyltransferase; Cholinergic Neurons; Disease Models, Animal; Dopaminergic Neurons; Male; Microglia; Neurons; Parkinson Disease; Parkinsonian Disorders; Pars Compacta; Pedunculopontine Tegmental Nucleus; Protein Aggregation, Pathological; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase | 2016 |
Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Cycloheximide; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Humans; Immunohistochemistry; Male; Mice; Mice, SCID; Microtubule-Associated Proteins; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Transcription Factor CHOP; Transplantation, Heterologous; Vacuoles | 2015 |
Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors.
Topics: Acetylation; Acetylcysteine; Animals; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Dopaminergic Neurons; Glial Cell Line-Derived Neurotrophic Factor; Histone Deacetylase Inhibitors; Histones; Male; Neuroprotective Agents; Parkinson Disease; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Up-Regulation; Valproic Acid | 2015 |
Hydrogen Peroxide Induce Human Cytomegalovirus Replication through the Activation of p38-MAPK Signaling Pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; Disease Models, Animal; Fibroblasts; Genes, Immediate-Early; Humans; Hydrogen Peroxide; Male; Mice, Inbred BALB C; Oxidants; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Signal Transduction; Transcription, Genetic; Virus Replication | 2015 |
Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Choline Deficiency; Cytoprotection; Disease Models, Animal; Hypolipidemic Agents; Lipids; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Ursodeoxycholic Acid | 2016 |
N-acetylcysteine S-nitrosothiol Nanoparticles Prevent Wound Expansion and Accelerate Wound Closure in a Murine Burn Model.
Topics: Acetylcysteine; Administration, Cutaneous; Animals; Burns; Disease Models, Animal; Mice; Mice, Inbred BALB C; Nanoparticles; S-Nitrosothiols; Wound Healing | 2015 |
Effect of N-acetylcysteine and allopurinol combination to protect spinal cord ischemia/reperfusion injury induced by aortic cross-clamping in rat model.
Topics: Acetylcysteine; Allopurinol; Animals; Aorta, Thoracic; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Ligation; Male; Neuroprotective Agents; Rats; Reperfusion Injury; Spinal Cord Ischemia | 2015 |
Antioxidant Therapies for Ulcerative Dermatitis: A Potential Model for Skin Picking Disorder.
Topics: Acetylcysteine; Animals; Antioxidants; Dermatitis; Disease Models, Animal; Female; Glutathione; Humans; Male; Mice; Mice, Inbred C57BL; Self-Injurious Behavior; Skin Ulcer | 2015 |
N-acetylcysteine Ameliorates the Erectile Dysfunction Caused by Chronic Intermittent Hypoxia in Rats: Partly Involvement of Endoplasmic Reticulum Stress.
Topics: Acetylcysteine; Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Endoplasmic Reticulum Stress; Erectile Dysfunction; Free Radical Scavengers; Hypoxia; Immunohistochemistry; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2015 |
N-acetylcysteine treatment ameliorates the skeletal phenotype of a mouse model of diastrophic dysplasia.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Bone and Bones; Cell Proliferation; Chondrocytes; Disease Models, Animal; Dwarfism; Embryo, Mammalian; Female; Growth and Development; Humans; Male; Mice; Pregnancy; Proteoglycans | 2015 |
Effect of N-Acetylcysteine on Adipose-Derived Stem Cell and Autologous Fat Graft Survival in a Mouse Model.
Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Disease Models, Animal; Flow Cytometry; Graft Survival; Male; Mice; Mice, Inbred C57BL; Random Allocation; Reference Values; Stem Cell Transplantation; Tissue and Organ Harvesting; Transplantation, Autologous | 2015 |
N-acetylcysteine Prevents Gentamicin Ototoxicity in a Rat Model.
Topics: Acetylcysteine; Animals; Cochlea; Disease Models, Animal; Ear Diseases; Evoked Potentials, Auditory, Brain Stem; Female; Free Radical Scavengers; Gentamicins; Otoacoustic Emissions, Spontaneous; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2015 |
Co-administration of N-Acetylcysteine and Acetaminophen Efficiently Blocks Acetaminophen Toxicity.
Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Combinations; Gene Expression Regulation, Enzymologic; Male; Mice; Transaminases | 2015 |
G2019S LRRK2 and aging confer susceptibility to proteasome inhibitor-induced neurotoxicity in nigrostriatal dopaminergic system.
Topics: Acetylcysteine; Aging; Animals; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopaminergic Neurons; Genetic Predisposition to Disease; Mice, Transgenic; Microglia; Motor Activity; Mutation; Neurodegenerative Diseases; Protein Serine-Threonine Kinases; Substantia Nigra; Tyrosine 3-Monooxygenase | 2015 |
N-acetylcysteine prevents stress-induced anxiety behavior in zebrafish.
Topics: Acetylcysteine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Disease Models, Animal; Female; Humans; Male; Stress, Physiological; Translational Research, Biomedical; Zebrafish | 2015 |
Protective effect of N-acetylcysteine on cyclophosphamide-induced cardiotoxicity in rats.
Topics: Acetylcysteine; Animals; Cardiotoxicity; Cyclophosphamide; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heart Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar | 2015 |
N-acetylcysteine protects against liver injure induced by carbon tetrachloride via activation of the Nrf2/HO-1 pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Heme Oxygenase (Decyclizing); Liver; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Up-Regulation | 2015 |
Berberine attenuates CCN2-induced IL-1β expression and prevents cartilage degradation in a rat model of osteoarthritis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Berberine; Cartilage; Cells, Cultured; Connective Tissue Growth Factor; Disease Models, Animal; Fibroblasts; Humans; Interleukin-1beta; MAP Kinase Kinase Kinase 5; NF-kappa B; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Vitronectin; Recombinant Proteins; Signal Transduction | 2015 |
The bifunctional μ opioid agonist/antioxidant [Dmt(1)]DALDA is a superior analgesic in an animal model of complex regional pain syndrome-type i.
Topics: Acetylcysteine; Analgesics, Opioid; Animals; Antioxidants; Area Under Curve; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Hot Temperature; Hyperalgesia; Male; Morphine; Oligopeptides; Rats, Long-Evans; Receptors, Opioid, mu; Reflex Sympathetic Dystrophy; Touch | 2015 |
Acrolein contributes to TRPA1 up-regulation in peripheral and central sensory hypersensitivity following spinal cord injury.
Topics: Acetylcysteine; Acrolein; Animals; Disease Models, Animal; Ganglia, Spinal; Hydralazine; Hyperalgesia; Locomotion; Male; Neuralgia; Pain Threshold; Rats; Rats, Sprague-Dawley; Skin; Spinal Cord; Spinal Cord Injuries; TRPA1 Cation Channel; TRPC Cation Channels; Up-Regulation; Vasodilator Agents | 2015 |
Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model.
Topics: Acetylcysteine; Acyl Coenzyme A; Animals; Apoptosis; Caspase 2; Choline Deficiency; Diet, Western; Disease Models, Animal; Liver; Liver Cirrhosis; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pantothenic Acid; Phosphotransferases (Alcohol Group Acceptor); Vitamin B Complex | 2016 |
Renal Protective Effect of Probucol in Rats with Contrast-Induced Nephropathy and its Underlying Mechanism.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Contrast Media; Creatinine; Deoxyguanosine; Disease Models, Animal; Immunohistochemistry; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitrogen; Oxidative Stress; Probucol; Rats; Rats, Wistar; Superoxide Dismutase | 2015 |
N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy.
Topics: Acetylcysteine; Animals; Calcium; Calcium-Binding Proteins; Cardiomyopathy, Hypertrophic, Familial; Carrier Proteins; Diastole; Disease Models, Animal; Female; Free Radical Scavengers; Heart Ventricles; Male; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myofibrils; Oxidative Stress; Phosphorylation; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tropomyosin | 2015 |
Antioxidants can increase melanoma metastasis in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Chromans; Dietary Supplements; Disease Models, Animal; Glutathione; Humans; Male; Melanoma; Mice; Neoplasm Metastasis | 2015 |
Is montelukast as effective as N-acetylcysteine in hepatic injury due to acetaminophen intoxication in rats?
Topics: Acetaminophen; Acetates; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cyclopropanes; Cytochrome P-450 CYP1A2 Inducers; Disease Models, Animal; Free Radical Scavengers; Male; Quinolines; Rats; Rats, Wistar; Sulfides | 2016 |
Galangin Prevents Acute Hepatorenal Toxicity in Novel Propacetamol-Induced Acetaminophen-Overdosed Mice.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Alpinia; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Disease Models, Animal; Flavonoids; Glutathione; Helichrysum; Liver; Male; Mice, Inbred BALB C; Oxidative Stress; Phytotherapy; Plant Extracts; Protective Agents; Silymarin | 2015 |
Elevated H2 O2 levels in trinitrobenzene sulfate-induced colitis rats contributes to visceral hyperalgesia through interaction with the transient receptor potential ankyrin 1 cation channel.
Topics: Abdominal Pain; Acetanilides; Acetylcysteine; Administration, Intravenous; Animals; Colitis; Colon; Disease Models, Animal; Free Radical Scavengers; Hydrogen Peroxide; Hyperalgesia; Male; Pain Threshold; Purines; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Trinitrobenzenesulfonic Acid; TRPV Cation Channels; Up-Regulation; Visceral Pain | 2016 |
Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.
Topics: Acetylcysteine; Animals; Biological Transport; Caspase 3; Caspase 7; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Humans; Induced Pluripotent Stem Cells; Karyotyping; Membrane Potentials; Mice; Mice, SCID; Mitochondria; Motor Neurons; Muscular Atrophy, Spinal; Polymerase Chain Reaction; Prosencephalon | 2016 |
N-acetylcysteine modulates angiogenesis and vasodilation in stomach such as DNA damage in blood of portal hypertensive rats.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Comet Assay; Disease Models, Animal; DNA Damage; Gastric Mucosa; Hypertension, Portal; Immunohistochemistry; Male; Neovascularization, Pathologic; Nitric Oxide Synthase Type III; Portal Pressure; Rats, Wistar; Stomach; Tyrosine; Vascular Endothelial Growth Factor A; Vasodilation | 2015 |
Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects.
Topics: Acetylcysteine; Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Depression; Disease Models, Animal; Fluoxetine; Janus Kinases; Male; Oxidative Stress; Rats, Wistar; Signal Transduction; STAT Transcription Factors; Swimming | 2016 |
[Study on the therapeutic effects of tetrandrine combined with N-acetylcysteine on experimental silicosis of rats].
Topics: Acetylcysteine; Animals; Benzylisoquinolines; Disease Models, Animal; Dust; Hydroxyproline; Interleukin-6; Lung; Malondialdehyde; Pulmonary Fibrosis; Quartz; Rats; Rats, Wistar; Silicon Dioxide; Silicosis; Tumor Necrosis Factor-alpha | 2015 |
The effects of N-acetylcysteine on cisplatin-induced changes of cardiodynamic parameters within coronary autoregulation range in isolated rat hearts.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Cardiotonic Agents; Cisplatin; Coronary Circulation; Coronary Vessels; Cytoprotection; Disease Models, Animal; Heart Diseases; Heart Rate; Homeostasis; Isolated Heart Preparation; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Wistar; Ventricular Function, Left; Ventricular Pressure | 2016 |
GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function.
Topics: Acetylcysteine; Animals; Central Nervous System; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Gene Expression Regulation, Developmental; Glial Cell Line-Derived Neurotrophic Factor; Humans; Kidney; Mice; Neostriatum; Neuroprotective Agents; Parkinson Disease, Secondary; Substantia Nigra | 2015 |
In Vitro Efficacy of Nonantibiotic Treatments on Biofilm Disruption of Gram-Negative Pathogens and an In Vivo Model of Infectious Endometritis Utilizing Isolates from the Equine Uterus.
Topics: Acetylcysteine; Animals; Anti-Infective Agents; Biofilms; Biomass; Disease Models, Animal; Edetic Acid; Endometritis; Female; Gram-Negative Bacteria; Horses; Hydrogen Peroxide; Luminescent Measurements; Microbial Viability; Staining and Labeling; Uterus | 2016 |
Role of mitochondria and NADPH oxidase derived reactive oxygen species in hyperoxaluria induced nephrolithiasis: therapeutic intervention with combinatorial therapy of N-acetyl cysteine and Apocynin.
Topics: Acetophenones; Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Hyperoxaluria; Male; Mitochondria; NADPH Oxidases; Nephrolithiasis; Rats, Wistar; Reactive Oxygen Species; Treatment Outcome | 2016 |
Genistein alleviates lead-induced neurotoxicity in vitro and in vivo: Involvement of multiple signaling pathways.
Topics: Acetylcysteine; Animals; Catalase; Disease Models, Animal; Dose-Response Relationship, Drug; Free Radical Scavengers; Genistein; In Situ Nick-End Labeling; Lead; Male; Maze Learning; Mitogen-Activated Protein Kinase Kinases; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; PC12 Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spatial Memory; Superoxide Dismutase | 2016 |
N-Acetylcysteine and Ceftriaxone as Preconditioning Strategies in Focal Brain Ischemia: Influence on Glutamate Transporters Expression.
Topics: Acetylcysteine; Analysis of Variance; Animals; Brain; Brain Edema; Brain Infarction; Ceftriaxone; Disease Models, Animal; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Nervous System Diseases; Neuroprotective Agents; Rats; Rats, Wistar; RNA, Messenger | 2016 |
N-acetylcysteine Ameliorates Prostatitis via miR-141 Regulating Keap1/Nrf2 Signaling.
Topics: Acetylcysteine; Animals; Carrageenan; Cyclooxygenase 2; Disease Models, Animal; Kelch-Like ECH-Associated Protein 1; Male; MicroRNAs; NF-E2-Related Factor 2; Oxidative Stress; Prostatitis; Rats; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Paracetamol-induced nephrotoxicity and oxidative stress in rats: the protective role of Nigella sativa.
Topics: Acetaminophen; Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Creatinine; Cytoprotection; Disease Models, Animal; Ethanol; Female; Glutathione; Kidney; Kidney Diseases; Malondialdehyde; Nigella sativa; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Wistar; Seeds; Solvents; Superoxide Dismutase; Urea | 2016 |
The effects of antioxidants on a porcine model of liver hemorrhage.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Crystalloid Solutions; Deferoxamine; Disease Models, Animal; Hepatectomy; Immunohistochemistry; Isotonic Solutions; Liver; Male; Random Allocation; Resuscitation; Shock, Hemorrhagic; Swine | 2016 |
N-acetylcysteine decreases binge eating in a rodent model.
Topics: Acetylcysteine; Animals; Binge-Eating Disorder; Conditioning, Operant; Diet, High-Fat; Disease Models, Animal; Feeding Behavior; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley | 2016 |
Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury.
Topics: Acetylcysteine; Animals; Antioxidants; Benzenesulfonates; Blast Injuries; Brain Injuries, Traumatic; Cytoprotection; Disease Models, Animal; Hippocampus; Male; Neuroprotective Agents; Protein Aggregation, Pathological; Rats; Rats, Long-Evans; tau Proteins | 2016 |
Investigation of N-acetylcysteine on contralateral testis tissue injury by experimental testicular torsion: long-term effect.
Topics: Acetylcysteine; Animals; Catalase; Disease Models, Animal; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Male; Malondialdehyde; Rats; Spermatic Cord Torsion; Superoxide Dismutase; Testicular Diseases; Time Factors | 2016 |
N-acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure.
Topics: Acetylcysteine; Animals; Antioxidants; Collagen Type I; Collagen Type III; Disease Models, Animal; Fibrosis; Genetic Predisposition to Disease; Heart Failure; Male; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Oxidative Stress; Phenotype; Protein Serine-Threonine Kinases; Time Factors; Ultrasonography; Ventricular Function, Left; Ventricular Remodeling | 2016 |
Effects of N-acetylcysteine and ethyl pyruvate on ischemia-reperfusion injury in experimental electrical burn model.
Topics: Acetylcysteine; Animals; Burns, Electric; Disease Models, Animal; Female; Free Radical Scavengers; Male; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury | 2016 |
Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish.
Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Benzodioxoles; Biliary Atresia; Disease Models, Animal; Glutathione; Hepatocytes; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Liver; NF-E2-Related Factor 2; Oxidation-Reduction; Sulfoxides; Zebrafish | 2016 |
A histological and immunohistochemical study of the effects of N-acetyl cysteine on retinopathy of prematurity by modifying insulin-like growth factor-1.
Topics: Acetylcysteine; Animals; Animals, Newborn; Cell Line, Tumor; Disease Models, Animal; Free Radical Scavengers; Gene Expression Regulation, Developmental; Immunohistochemistry; Insulin-Like Growth Factor I; Rats; Retinal Pigment Epithelium; Retinal Vessels; Retinopathy of Prematurity | 2016 |
Piperlongumine Suppresses Dendritic Cell Maturation by Reducing Production of Reactive Oxygen Species and Has Therapeutic Potential for Rheumatoid Arthritis.
Topics: Acetylcysteine; Alcohol Oxidoreductases; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; B7-1 Antigen; B7-2 Antigen; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Collagen; Cytokines; Dendritic Cells; Dioxolanes; Disease Models, Animal; Glutathione S-Transferase pi; Interferon-gamma; Interleukin-12; Interleukin-6; Mice; Reactive Oxygen Species; Signal Transduction | 2016 |
Altered localization and functionality of TAR DNA Binding Protein 43 (TDP-43) in niemann- pick disease type C.
Topics: Acetylcysteine; Animals; beta-Cyclodextrins; Brain; Cell Nucleus; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred BALB C; Mice, Transgenic; Middle Aged; Neurons; Neuroprotective Agents; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Spinal Cord | 2016 |
N-acetylcysteine supplementation reduces oxidative stress for cytosine arabinoside in rat model.
Topics: Acetylcysteine; Animals; Antioxidants; Conjunctiva; Cornea; Cytarabine; Dietary Supplements; Disease Models, Animal; Free Radical Scavengers; Immunosuppressive Agents; Oxidative Stress; Rats; Rats, Wistar | 2017 |
Antiinflammatory Effect of N-Acetylcysteine Combined with Exogenous Surfactant in Meconium-Induced Lung Injury.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Lung; Meconium Aspiration Syndrome; Oxidative Stress; Pulmonary Surfactants; Rabbits; Treatment Outcome | 2016 |
N-Acetyl-l-cysteine exacerbates generation of IL-10 in cells stimulated with endotoxin in vitro and produces antipyresis via IL-10 dependent pathway in vivo.
Topics: Acetylcysteine; Animals; Antibodies, Blocking; Antipyretics; Body Temperature; Cells, Cultured; Dinoprostone; Disease Models, Animal; Fever; Interleukin-10; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Rats; Rats, Wistar | 2016 |
A combination of an iron chelator with an antioxidant effectively diminishes the dendritic loss, tau-hyperphosphorylation, amyloids-β accumulation and brain mitochondrial dynamic disruption in rats with chronic iron-overload.
Topics: Acetylcysteine; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Benzoates; Brain; Deferasirox; Deferoxamine; Dendrites; Diet; Disease Models, Animal; Drug Therapy, Combination; Iron; Iron Chelating Agents; Iron Overload; Male; Mitochondrial Dynamics; Neurodegenerative Diseases; Phosphorylation; Random Allocation; Rats, Wistar; tau Proteins; Triazoles | 2016 |
Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish.
Topics: Acetylcysteine; Administration, Ophthalmic; Animals; Disease Models, Animal; Light; Macular Degeneration; Vitreous Body; Zebrafish | 2016 |
Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes.
Topics: Acetylcysteine; Animals; Antidotes; Antioxidants; Arsenicals; Blister; Chemical Warfare Agents; Disease Models, Animal; Female; Humans; Inflammation; Keratinocytes; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Molecular Chaperones; Patched-1 Receptor; Phenylbutyrates; Reactive Oxygen Species; Signal Transduction | 2016 |
Toward early estimation and treatment of addiction vulnerability: radial arm maze and N-acetyl cysteine before cocaine sensitization or nicotine self-administration in neonatal ventral hippocampal lesion rats.
Topics: Acetylcysteine; Animals; Animals, Newborn; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Drug-Seeking Behavior; Free Radical Scavengers; Hippocampus; Male; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2016 |
The Cardioprotective Role of N-Acetyl Cysteine Amide in the Prevention of Doxorubicin and Trastuzumab-Mediated Cardiac Dysfunction.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Drug Monitoring; Echocardiography; Female; Mice; Oxidative Stress; Trastuzumab; Treatment Outcome | 2016 |
Antioxidant Effect of Ukrain Versus N-Acetylcysteine Against Acute Biliary Pancreatitis in An Experimental Rat Model.
Topics: Acetylcysteine; Alanine Transaminase; Amylases; Animals; Antioxidants; Aspartate Aminotransferases; Berberine Alkaloids; Biliary Tract; Bilirubin; Disease Models, Animal; Humans; Lipase; Male; Malondialdehyde; Nitric Oxide; Oxidants; Oxidative Stress; Pancreas; Pancreatitis; Peroxidase; Phenanthridines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2017 |
N-Acetylcysteine and Desferoxamine Reduce Pulmonary Oxidative Stress Caused by Hemorrhagic Shock in a Porcine Model.
Topics: Acetylcysteine; Animals; Biomarkers; Colloids; Crystalloid Solutions; Deferoxamine; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Free Radical Scavengers; Glutathione Peroxidase; Humans; Infusions, Intravenous; Isotonic Solutions; Lung; Male; Oxidative Stress; Protein Carbonylation; Random Allocation; Rehydration Solutions; Shock, Hemorrhagic; Siderophores; Swine; Thiobarbituric Acid Reactive Substances | 2017 |
Thymoquinone mitigate ischemia-reperfusion-induced liver injury in rats: a pivotal role of nitric oxide signaling pathway.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Benzoquinones; Biomarkers; Cytoprotection; Disease Models, Animal; Glutathione; Lipid Peroxidation; Liver; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Rats, Wistar; Reperfusion Injury; Signal Transduction | 2017 |
Anxiolytic properties of N-acetylcysteine in mice.
Topics: Acetylcysteine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Body Temperature; Dark Adaptation; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fever; Interpersonal Relations; Male; Maze Learning; Mice; Time Factors | 2017 |
N-Acetylcysteine Use in Hepatic Ischemia/Reperfusion in Rats Minimizing Bowel Injury.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Intestinal Mucosa; Intestine, Small; Liver; Liver Diseases; Male; Rats; Rats, Wistar; Reperfusion Injury | 2016 |
Antioxidants Attenuate Acute and Chronic Itch: Peripheral and Central Mechanisms of Oxidative Stress in Pruritus.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Transformed; Central Nervous System; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Male; Malondialdehyde; Mice; Oxidative Stress; p-Methoxy-N-methylphenethylamine; Peripheral Nerves; Pruritus; Reactive Oxygen Species; Skin; Superoxide Dismutase; Time Factors | 2017 |
N-acetyl-cysteine exhibits potent anti-mycobacterial activity in addition to its known anti-oxidative functions.
Topics: Acetylcysteine; Adolescent; Adult; Animals; Anti-Bacterial Agents; Antioxidants; Case-Control Studies; Cell Death; Cell Line; Disease Models, Animal; Humans; Latent Tuberculosis; Lipid Peroxidation; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mycobacterium avium; Mycobacterium bovis; Mycobacterium tuberculosis; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Tuberculosis, Pulmonary; Young Adult | 2016 |
Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models.
Topics: Acetylcysteine; Animals; Bleomycin; Blotting, Western; Caveolin 1; Cytoprotection; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Idiopathic Pulmonary Fibrosis; Lung; Male; Platelet-Derived Growth Factor; Prednisone; Protective Agents; Pyridones; Rats, Wistar; Real-Time Polymerase Chain Reaction; Signal Transduction; Time Factors; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2017 |
Topics: Acetylcysteine; ADAMTS13 Protein; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Papio; Protein Multimerization; Purpura, Thrombotic Thrombocytopenic; von Willebrand Factor | 2017 |
N-acetylcysteine a possible protector against indomethacin-induced peptic ulcer: crosstalk between antioxidant, anti-inflammatory, and antiapoptotic mechanisms.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Antioxidants; Apoptosis; Caspase 3; Chemical and Drug Induced Liver Injury; Chemokines, CXC; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Gastric Mucosa; Glucosephosphate Dehydrogenase; Humans; Indomethacin; Interferon-gamma; Interleukin-1beta; Male; Oxidation-Reduction; Pain; Peroxidase; Proto-Oncogene Proteins c-bcl-2; Ranitidine; Rats; Rats, Wistar; Stomach Ulcer | 2017 |
Novel Role of the Mitochondrial Protein Fus1 in Protection from Premature Hearing Loss via Regulation of Oxidative Stress and Nutrient and Energy Sensing Pathways in the Inner Ear.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Gene Knockout Techniques; Hearing Loss; Humans; Mice; Microscopy, Electron, Transmission; Mitochondria; Oxidative Stress; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Spiral Ganglion; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins | 2017 |
Connexin40 correlates with oxidative stress in brains of traumatic brain injury rats.
Topics: Acetylcysteine; Analysis of Variance; Animals; Brain; Brain Edema; Brain Infarction; Brain Injuries, Traumatic; Connexins; Disease Models, Animal; Gap Junction alpha-5 Protein; Gene Expression Regulation; Male; Oxidative Stress; Rats; Rats, Wistar; Time Factors | 2017 |
N-acetylcysteine downregulates phosphorylated p-38 expression but does not reverse the increased superoxide anion levels in the spinal cord of rats with neuropathic pain.
Topics: Acetylcysteine; Animals; Blotting, Western; Constriction, Pathologic; Disease Models, Animal; Down-Regulation; Male; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Threshold; Phosphorylation; Rats; Rats, Wistar; Spinal Cord; Superoxides | 2017 |
Plastic changes at corticostriatal synapses predict improved motor function in a partial lesion model of Parkinson's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Male; Mice, Inbred C57BL; Motor Activity; Neural Pathways; Neuronal Plasticity; Parkinson Disease; Parkinsonian Disorders; Pars Compacta; Post-Synaptic Density; Rotarod Performance Test; Synapses | 2017 |
Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase.
Topics: Acetylcysteine; Aminoquinolines; Animals; Antioxidants; Buthionine Sulfoximine; Disease Models, Animal; Humans; Imiquimod; Inflammation; Kidney; Kidney Diseases; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Psoriasis | 2017 |
Short-term effects of N-acetylcysteine and ischemic preconditioning in a canine model of hepatic ischemia-reperfusion injury.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Coloring Agents; Disease Models, Animal; Dogs; Indocyanine Green; Ischemic Preconditioning; Liver Diseases; Reperfusion Injury | 2008 |
Randomized, blinded, placebo-controlled clinical trial of N-acetylcysteine in dogs with spinal cord trauma from acute intervertebral disc disease.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Dinoprost; Disease Models, Animal; Dog Diseases; Dogs; Female; Infusions, Intravenous; Intervertebral Disc; Intervertebral Disc Displacement; Laminectomy; Male; Oxidative Stress; Random Allocation; Spinal Cord Injuries; Time Factors | 2008 |
A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
Topics: Acetylcysteine; Adenomatous Polyposis Coli; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Time Factors; Transfection | 2008 |
Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's disease.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Benzoquinones; Brain; Disease Models, Animal; Dopamine; Free Radical Scavengers; Free Radicals; Humans; Hydrogen Peroxide; Mitochondria; Parkinson Disease; Rats; Sodium-Potassium-Exchanging ATPase | 2008 |
Protective effects of N-acetylcysteine on cyclosporine-A-induced nephrotoxicity.
Topics: Acetylcysteine; Acute Kidney Injury; Analysis of Variance; Animals; Biopsy, Needle; Blood Urea Nitrogen; Creatinine; Cyclosporine; Disease Models, Animal; Immunohistochemistry; Kidney; Male; Malondialdehyde; Microscopy; Nitric Oxide; Probability; Random Allocation; Rats; Rats, Wistar | 2008 |
Different effect of acute treatment with rosiglitazone on rat myocardial ischemia/reperfusion injury by administration method.
Topics: Acetylcysteine; Animals; Antioxidants; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; I-kappa B Proteins; Infusions, Intravenous; Injections, Intravenous; Male; Models, Biological; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Peroxidase; Phosphorylation; PPAR gamma; Protective Agents; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2008 |
[Effects of N-acetylcysteine on mRNA expression of monocyte chemotactic protein and macrophage inflammatory protein 2 in acute necrotizing pancreatitis: experiment with rats].
Topics: Acetylcysteine; Animals; Chemokine CCL2; Chemokine CXCL2; Disease Models, Animal; Free Radical Scavengers; Male; Pancreas; Pancreatitis, Acute Necrotizing; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Chronic nasal instillation of residual-oil fly ash (ROFA) induces brain lipid peroxidation and behavioral changes in rats.
Topics: Acetylcysteine; Administration, Intranasal; Air Pollutants; Animals; Behavior, Animal; Brain; Carbon; Coal Ash; Disease Models, Animal; Exploratory Behavior; Free Radical Scavengers; Lipid Peroxidation; Male; Motor Activity; Oxidative Stress; Particulate Matter; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2008 |
Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chemistry, Pharmaceutical; Chloramines; Disease Models, Animal; Drug Compounding; Injections, Intravenous; Leukotriene B4; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Lung; Male; Organ Size; Peptidyl-Dipeptidase A; Peroxidase; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Thromboxane B2; Tumor Necrosis Factor-alpha | 2008 |
Effects of early administration of dexamethasone, N-acetylcysteine and aprotinin on inflammatory and oxidant-antioxidant status after lung contusion in rats.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Aprotinin; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Catalase; Dexamethasone; Disease Models, Animal; Free Radical Scavengers; Male; Malondialdehyde; Neutrophils; Nitric Oxide; Oxidants; Pulmonary Alveoli; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Wounds, Nonpenetrating | 2009 |
Synergistic action of sodium selenite and N-acetylcysteine in acetaminophen-induced liver damage.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Combinations; Drug Synergism; Free Radical Scavengers; L-Lactate Dehydrogenase; Male; Mice; Sodium Selenite | 2008 |
Improving the cadmium-induced centriacinar emphysema model in rats by concomitant anti-oxidant treatment.
Topics: Acetylcysteine; Animals; Antioxidants; Cadmium Chloride; Disease Models, Animal; Lung Compliance; Male; Pulmonary Emphysema; Rats; Rats, Wistar | 2008 |
Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor gamma agonist.
Topics: Acetylcholine; Acetylcysteine; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Behavior, Animal; Cerebrovascular Disorders; Disease Models, Animal; Gene Expression Regulation; Humans; Hypoglycemic Agents; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Nitric Oxide Synthase; Peptide Fragments; Pioglitazone; PPAR gamma; Superoxide Dismutase; Thiazolidinediones | 2008 |
N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis.
Topics: Acetylcysteine; Animals; Autoantibodies; Disease Models, Animal; Energy Intake; Fatty Liver; Glutathione; Inflammation; Liver; Liver Function Tests; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Triglycerides | 2008 |
Oxidative stress causes alveolar bone loss in metabolic syndrome model mice with type 2 diabetes.
Topics: Acetylcysteine; Alveolar Bone Loss; Animals; Antioxidants; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Gingiva; Hydrogen Peroxide; Keratinocytes; Male; Mandible; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nitric Oxide Synthase Type III; Oxidative Stress; Reactive Oxygen Species | 2009 |
[Hemodynamic effects of N-acetylcysteine and ischemic preconditioning in a liver ischemia-reperfusion model].
Topics: Acetylcysteine; Animals; Cardiovascular Agents; Disease Models, Animal; Dogs; Hemodynamics; Ischemic Preconditioning; Liver; Reperfusion Injury | 2008 |
Free radical scavengers versus methylprednisolone in the prevention of experimentally induced heterotopic ossification.
Topics: Acetylcysteine; Allopurinol; Animals; Disease Models, Animal; Female; Free Radical Scavengers; Glucocorticoids; Hindlimb Suspension; Methylprednisolone; Ossification, Heterotopic; Placebos; Rabbits; Radiography | 2009 |
Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia.
Topics: Acetylcysteine; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Behavior, Animal; Brain; Cognition Disorders; Conditioning, Psychological; Cyclic AMP; Disease Models, Animal; Erythromycin; Exploratory Behavior; Fear; Female; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunits, Gs; Haloperidol; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphodiesterase Inhibitors; Psychophysics; Reflex, Startle; Rolipram; Time Factors | 2009 |
Effect of N-acetylcysteine on the murine model of colitis induced by dextran sodium sulfate through up-regulating PON1 activity.
Topics: Acetylcysteine; Animals; Antioxidants; Aryldialkylphosphatase; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Down-Regulation; Glutathione; Interleukin-1beta; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Severity of Illness Index; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.
Topics: Acetylcysteine; Animals; Antioxidants; Constriction; Disease Models, Animal; Glutathione Peroxidase; Ileum; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Artery, Superior; Oxidative Stress; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sexual Development; Sulfhydryl Compounds; Superoxide Dismutase; Thioctic Acid; Thioglycolates; Thiophenes | 2009 |
Effect of alpha-tocopherol, N-acetylcysteine and omeprazole on esophageal adenocarcinoma formation in a rat surgical model.
Topics: Acetylcysteine; Adenocarcinoma; alpha-Tocopherol; Animals; Disease Models, Animal; Esophageal Neoplasms; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Male; Omeprazole; Rats; Rats, Sprague-Dawley; Vitamin A | 2009 |
Effects of pentoxifylline and n-acetylcysteine on injuries caused by ischemia and reperfusion of splanchnic organs in rats.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Hemodynamics; Intestinal Mucosa; Intestine, Small; Male; Mesenteric Vascular Occlusion; Oxidative Stress; Pentoxifylline; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Shock; Splanchnic Circulation; Time Factors | 2008 |
Efficacy of combination of N-acetylcysteine, gentamicin, and amphotericin B for prevention of microbial colonization of ventricular assist devices.
Topics: Acetylcysteine; Amphotericin B; Animals; Anti-Bacterial Agents; Coated Materials, Biocompatible; Disease Models, Animal; Equipment Contamination; Gentamicins; Heart-Assist Devices; Humans; Prosthesis-Related Infections; Rabbits; Staphylococcal Infections; Staphylococcus aureus | 2009 |
Tissue oxidative stress level and remote organ injury in two-hit trauma model of sequential burn injury and peritoneal sepsis are attenuated with N-acetylcysteine treatment in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Burns; Cecum; Disease Models, Animal; Glutathione; Intestinal Perforation; Ligation; Liver; Lung; Male; Malondialdehyde; Oxidative Stress; Random Allocation; Rats; Rats, Wistar | 2009 |
N-Acetylcysteine reverses cocaine-induced metaplasticity.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cocaine-Related Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Free Radical Scavengers; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Secondary Prevention; Self Administration; Substance Withdrawal Syndrome | 2009 |
Nigral degeneration with inclusion body formation and behavioral changes in rats after proteasomal inhibition.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Behavior, Animal; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Hypokinesia; Inclusion Bodies; Male; Microscopy, Electron, Transmission; Motor Activity; Neurodegenerative Diseases; Neurons; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Substantia Nigra; Tyrosine 3-Monooxygenase | 2009 |
Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms.
Topics: Acetylcysteine; Actins; Animals; Animals, Genetically Modified; Antioxidants; Cardiomyopathy, Hypertrophic; Cell Size; Disease Models, Animal; Female; Fibrosis; Glutathione; Heart Failure, Systolic; Humans; Male; MAP Kinase Signaling System; Myocytes, Cardiac; Myosin Heavy Chains; NFATC Transcription Factors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Sulfhydryl Compounds; Ventricular Fibrillation | 2009 |
Acute liver acetaminophen toxicity in rabbits and the use of antidotes: a metabonomic approach in serum.
Topics: Acetaminophen; Acetylcysteine; Acute Disease; Alanine Transaminase; Animals; Antidotes; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Liver; Magnetic Resonance Spectroscopy; Male; Rabbits; Silybin; Silymarin | 2009 |
Can N-acetylcysteine preserve peritoneal function and morphology in encapsulating peritoneal sclerosis?
Topics: Acetylcysteine; Animals; Disease Models, Animal; Endothelial Cells; Female; Free Radical Scavengers; Injections, Intraperitoneal; Oxidative Stress; Peritoneal Dialysis; Peritoneal Diseases; Peritoneum; Rats; Rats, Wistar; Sclerosis; Treatment Outcome | 2009 |
Prevention of selenite-induced cataractogenesis by N-acetylcysteine in rats.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Cataract; Disease Models, Animal; Free Radical Scavengers; Glutathione; Lens, Crystalline; Malondialdehyde; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Sodium Selenite | 2009 |
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction.
Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Exercise Therapy; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Physical Exertion; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Time Factors; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Pressure; Ventricular Remodeling | 2009 |
Partial inhibition of proteasome activity enhances remyelination after cuprizone-induced demyelination.
Topics: Acetylcysteine; Animals; Corpus Callosum; Cuprizone; Cysteine Proteinase Inhibitors; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Regeneration; Neurotoxins; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Treatment Outcome | 2009 |
Effects of N-acetylcysteine on intestinal reoxygenation injury in hypoxic newborn piglets resuscitated with 100% oxygen.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Enterocolitis; Hypoxia; Ileum; Oxygen; Oxygen Inhalation Therapy; Reperfusion Injury; Splanchnic Circulation; Swine | 2009 |
Oral N-acetylcysteine attenuates pulmonary emphysema and alveolar septal cell apoptosis in smoking-induced COPD in rats.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Apoptosis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Male; Pulmonary Alveoli; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats; Rats, Sprague-Dawley; Smoking; Vascular Endothelial Growth Factor A | 2009 |
Chemical synthesis of N-acetylcysteine conjugates of bile acids and in vivo formation in cholestatic rats as shown by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.
Topics: Acetylcysteine; Animals; Bile Acids and Salts; Carboxylesterase; Cholestasis; Chromatography, Liquid; Disease Models, Animal; Humans; Liver; Male; Rabbits; Rats; Spectrometry, Mass, Electrospray Ionization | 2009 |
Effect of chitosan-N-acetylcysteine conjugate in a mouse model of botulinum toxin B-induced dry eye.
Topics: Acetylcysteine; Administration, Topical; Animals; Blinking; Botulinum Toxins; Botulinum Toxins, Type A; Chitosan; Conjunctiva; Cornea; Cytokines; Disease Models, Animal; Dry Eye Syndromes; Female; Fluorescent Antibody Technique, Indirect; Fluorometholone; Lacrimal Apparatus; Mice; Mice, Inbred CBA; Ophthalmic Solutions; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tears | 2009 |
N-acetylcysteine improves group B streptococcus clearance in a rat model of chronic ethanol ingestion.
Topics: Acetylcysteine; Alcoholism; Animals; Disease Models, Animal; Ethanol; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Streptococcus agalactiae | 2009 |
N-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production.
Topics: Acetylcysteine; Animals; Apolipoproteins E; Atherosclerosis; Dietary Fats; Disease Models, Animal; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Severity of Illness Index; Superoxides | 2009 |
A rabbit model to study biochemical damage to the lens after vitrectomy: effects of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; Cataract; Disease Models, Animal; Lens, Crystalline; Rabbits; Vitrectomy | 2009 |
Re-protective effects of pre- and post-laparoscopy conditioning, zinc, pentoxifylline, and N-acetylcysteine in an animal model of laparoscopy-induced ischemia/reperfusion injury of the kidney.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Kidney; Laparoscopy; Male; Pentoxifylline; Pneumoperitoneum, Artificial; Postoperative Care; Preoperative Care; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Zinc | 2009 |
N-acetylcysteine-enhanced contrast provides cardiorenal protection.
Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Contrast Media; Creatinine; Disease Models, Animal; Feasibility Studies; Free Radical Scavengers; Iopamidol; Kidney; Kidney Diseases; Myocardial Infarction; Myocardium; Risk Factors; Swine | 2009 |
Contrast loaded with N-acetylcysteine for coronary imaging during percutaneous coronary intervention: a new concept for renal and myocardial protection during percutaneous coronary intervention.
Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Contrast Media; Disease Models, Animal; Free Radical Scavengers; Iopamidol; Kidney; Kidney Diseases; Myocardial Infarction; Myocardium | 2009 |
Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome.
Topics: Acetylcysteine; Activating Transcription Factors; Animals; Antidotes; Antioxidants; Blood Proteins; Cell Proliferation; Cyclin D1; Disease Models, Animal; Erythrocytes; Guinea Pigs; Liposomes; Lung; Lung Injury; Male; Mitogen-Activated Protein Kinases; Mustard Gas; Neutrophil Infiltration; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pulmonary Eosinophilia; Time Factors; Tocopherols; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2009 |
N-acetylcysteine alters apoptotic gene expression in axotomised primary sensory afferent subpopulations.
Topics: Acetylcysteine; Animals; Apoptosis; Axotomy; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Cytoprotection; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Ganglia, Spinal; Gene Expression Regulation; Male; Muscle, Skeletal; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger; Sensory Receptor Cells; Skin; Up-Regulation | 2009 |
Chronic heart failure and the substrate for atrial fibrillation.
Topics: Acetylcysteine; Action Potentials; Animals; Atrial Fibrillation; Atrial Function, Left; Calcium Channels, L-Type; Calcium Signaling; Cardiac Pacing, Artificial; Chronic Disease; Disease Models, Animal; Dogs; Female; Fibrosis; Heart Conduction System; Heart Failure; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Oxidative Stress; Pilot Projects; Potassium Channels; Receptor, Angiotensin, Type 1; Refractory Period, Electrophysiological; Time Factors; Ventricular Function, Left | 2009 |
NAC is associated with additional alleviation of lung injury induced by invasive pulmonary aspergillosis in a neutropenic model.
Topics: Acetylcysteine; Amphotericin B; Animals; Antifungal Agents; Disease Models, Animal; Humans; Interleukin-10; Invasive Pulmonary Aspergillosis; Lung Injury; Male; Mice; Mice, Inbred BALB C; Neutropenia; Oxidative Stress; Random Allocation; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2009 |
Intense correlation between brain infarction and protein-conjugated acrolein.
Topics: Acetylcysteine; Acrolein; Animals; Brain; Carrier Proteins; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Photochemistry; Rose Bengal; Spermidine; Spermine; Time Factors; Up-Regulation | 2009 |
[Protective effects and mechanism of N-acetylcysteine on cardiac injury induced by ischemia/reperfusion in diabetic rats].
Topics: Acetylcysteine; Animals; Diabetes Complications; Disease Models, Animal; Female; Humans; Ischemia; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Mechanism of the protective effects of N-acetylcysteine on the heart of brain-dead Ba-Ma miniature pigs.
Topics: Acetylcysteine; Animals; Brain Death; Disease Models, Animal; DNA Primers; Fasting; Heart; Interleukin-1beta; Interleukin-6; Intermittent Positive-Pressure Ventilation; Intubation, Intratracheal; Reverse Transcriptase Polymerase Chain Reaction; RNA; Swine; Swine, Miniature; Troponin T; Tumor Necrosis Factor-alpha | 2009 |
N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis.
Topics: Acetylcysteine; Animals; Apoptosis; Cartilage, Articular; Caspase 3; Chondrocytes; Disease Models, Animal; Free Radical Scavengers; Glutathione; Injections, Intra-Articular; Male; Nitric Oxide; Osteoarthritis; Rabbits; Rats; Reactive Oxygen Species; Tumor Suppressor Protein p53; Up-Regulation | 2010 |
Neuroprotective interventions: is it too late?
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain Injuries; Disease Models, Animal; Female; Humans; Hypothermia, Induced; Male; Myelin Sheath; Neuroprotective Agents; Oligodendroglia; Oxidative Stress; Polysaccharides; Pregnancy; Prenatal Exposure Delayed Effects; Research Design; Time Factors | 2009 |
Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress.
Topics: Acetylcysteine; Action Potentials; Age Factors; Aging; Animals; Antioxidants; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Communication; Computer Simulation; Disease Models, Animal; Electrocardiography; Enzyme Activation; Fibrosis; Heart Ventricles; Hydrogen Peroxide; Male; Models, Cardiovascular; Myocytes, Cardiac; Oxidants; Oxidative Stress; Perfusion; Protein Kinase Inhibitors; Rabbits; Rats; Rats, Inbred F344; Sulfonamides; Tachycardia, Ventricular; Time Factors; Ventricular Fibrillation | 2009 |
Increased oxidative stress in the airway and development of allergic inflammation in a mouse model of asthma.
Topics: Acetylcysteine; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione; Immunization; Inflammation; Lung; Mice; Mice, Inbred BALB C; Mucins; Ovalbumin; Oxidative Stress; Respiratory Mucosa | 2009 |
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.
Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Catechin; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Glutathione; Hyperoxia; Hypoxia; Ischemia; Lipid Peroxidation; Metalloporphyrins; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Protective Agents; Retinal Neovascularization; Retinal Vessels; Tyrosine | 2010 |
Prevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Animals, Newborn; Anticarcinogenic Agents; Budesonide; Disease Models, Animal; Female; Isothiocyanates; Lung Neoplasms; Male; Mice; Tobacco Smoke Pollution | 2010 |
Reactive oxygen species generated by renal ischemia and reperfusion trigger protection against subsequent renal ischemia and reperfusion injury in mice.
Topics: Acetylcysteine; Animals; Catalase; Creatinine; Disease Models, Animal; Heat-Shock Proteins; Ischemic Preconditioning; Kidney; Kidney Diseases; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; Molecular Chaperones; Neoplasm Proteins; Nitric Oxide Synthase Type II; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Superoxides | 2010 |
Cerebral amino acid profiles after hypoxia-reoxygenation and N-acetylcysteine treatment in the newborn piglet.
Topics: Acetylcysteine; Amino Acids; Animals; Animals, Newborn; Antioxidants; Asphyxia Neonatorum; Cerebrum; Disease Models, Animal; Drug Administration Schedule; Free Radical Scavengers; Humans; Hypoxia-Ischemia, Brain; Hypoxia, Brain; Infant, Newborn; Metabolome; Oxygen; Reperfusion Injury; Resuscitation; Swine | 2010 |
The effects of N-acetylcysteine on testicular damage in experimental testicular ischemia/reperfusion injury.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Male; Malondialdehyde; Peroxidase; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Statistics, Nonparametric; Testis; Thiobarbituric Acid Reactive Substances | 2010 |
Effect of speed of rewarming and administration of anti-inflammatory or anti-oxidant agents on acute lung injury in an intestinal ischemia model treated with therapeutic hypothermia.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Dexamethasone; Disease Models, Animal; Hypothermia, Induced; Intestines; Ischemia; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Rewarming; Survival Rate; Time Factors | 2010 |
Trimetazidine and N-acetylcysteine in attenuating hind-limb ischemia and reperfusion injuries: experimental study in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Creatine Kinase; Disease Models, Animal; Glutathione; Hindlimb; Male; Malondialdehyde; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Time Factors; Trimetazidine | 2009 |
Antioxidant therapy reverses impaired graft healing in hypercholesterolemic rabbits.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta, Abdominal; Blood Vessel Prosthesis Implantation; Cell Movement; Cell Proliferation; Cholesterol; Disease Models, Animal; Endothelial Cells; Hypercholesterolemia; Hyperplasia; Macrophages; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Rabbits; Thiobarbituric Acid Reactive Substances; Tyrosine; Wound Healing | 2010 |
[Inhibitory effect of N-acetylcysteine upon atherosclerotic processes in rabbit carotid].
Topics: Acetylcysteine; Animals; Atherosclerosis; Carotid Arteries; Disease Models, Animal; Lipoproteins, LDL; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Rabbits | 2009 |
Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Deferoxamine; Disease Models, Animal; Kidney; Lung; Male; Multiple Organ Failure; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Urea | 2011 |
Oral N-acetylcysteine has a deleterious effect in acute iron intoxication in rats.
Topics: Acetylcysteine; Acute Disease; Administration, Oral; Animals; Antidotes; Antioxidants; Disease Models, Animal; Gastrointestinal Tract; Glutathione; Iron; Liver; Male; Rats; Rats, Wistar | 2010 |
Retinal oxidative stress induced by intraocular hypertension in rats may be ameliorated by brimonidine treatment and N-acetyl cysteine supplementation.
Topics: Acetylcysteine; Animals; Brimonidine Tartrate; Catalase; Disease Models, Animal; Drug Therapy, Combination; Glutathione Peroxidase; Hyaluronic Acid; Intraocular Pressure; Male; Malondialdehyde; Nitric Oxide; Ocular Hypertension; Oxidative Stress; Quinoxalines; Rats; Rats, Sprague-Dawley; Retinal Diseases; Tonometry, Ocular | 2009 |
Gastroprotective effect of barbatusin and 3-beta-hydroxy-3-deoxibarbatusin, quinonoid diterpenes isolated from Plectranthus grandis, in ethanol-induced gastric lesions in mice.
Topics: Acetylcysteine; Animals; Anti-Ulcer Agents; Antioxidants; Capsaicin; Disease Models, Animal; Diterpenes; Ethanol; Gastric Mucosa; Glyburide; Indomethacin; Male; Mice; Mucus; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Extracts; Plant Leaves; Plectranthus; Quinones; Stomach; Stomach Ulcer; Sulfhydryl Compounds; Thiobarbiturates | 2010 |
Intracellular thiol redox status regulates lymphangiogenesis and dictates corneal limbal graft survival.
Topics: Acetylcysteine; Animals; Blotting, Western; Corneal Neovascularization; Corneal Transplantation; Disease Models, Animal; Endothelium, Lymphatic; Enzyme-Linked Immunosorbent Assay; Glutathione; Glycoproteins; Graft Survival; Limbus Corneae; Lymphangiogenesis; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neuropilin-2; Oxidation-Reduction; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-3 | 2010 |
Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson's disease.
Topics: Acetylcysteine; alpha-Synuclein; Animals; Apomorphine; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; Dopamine Agonists; Iron; Magnetic Resonance Imaging; Male; Mesencephalon; Motor Activity; Neurons; Parkinsonian Disorders; Random Allocation; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2010 |
Reactive oxygen species inhibit adhesion of mesenchymal stem cells implanted into ischemic myocardium via interference of focal adhesion complex.
Topics: Acetylcysteine; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Focal Adhesion Kinase 1; Focal Adhesions; Free Radical Scavengers; Gene Knock-In Techniques; Graft Survival; Hydrogen Peroxide; Integrins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Ischemia; Oxidants; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Regeneration; src-Family Kinases | 2010 |
S-allylcysteine is effective as a chemopreventive agent against porcine serum-induced hepatic fibrosis in rats.
Topics: Acetylcysteine; Actins; Alanine Transaminase; Animals; Anticarcinogenic Agents; Chemoprevention; Cysteine; Disease Models, Animal; Hepatic Stellate Cells; Lipid Peroxidation; Liver; Liver Cirrhosis; Male; Rats; Rats, Wistar; Serum; Sulfhydryl Compounds; Swine; Treatment Outcome | 2009 |
N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Chromium; Dermatitis, Allergic Contact; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Female; Glutathione; Guinea Pigs; Hydrogen Peroxide; Malondialdehyde; Reactive Oxygen Species; Severity of Illness Index; Skin | 2010 |
Is there a role for antioxidants in prevention of pulmonary hypoplasia in nitrofen-induced rat model of congenital diaphragmatic hernia?
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Drug Synergism; Female; Fetus; Free Radical Scavengers; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Lipid Peroxidation; Lung; Lung Diseases; Male; Maternal-Fetal Exchange; Pesticides; Phenyl Ethers; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E | 2010 |
The anti-inflammatory agent N-acetyl cysteine exacerbates endotoxin-induced hypoxemia and hypotension and induces polycythemia in the ovine fetus.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Disease Models, Animal; Drug Synergism; Fetus; Gestational Age; Hemodynamics; Hypotension; Hypoxia; Lipopolysaccharides; Oximetry; Oxygen; Polycythemia; Sheep | 2010 |
Exposure to mycotoxins increases the allergic immune response in a murine asthma model.
Topics: Acetylcysteine; Actins; Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Dendritic Cells; Disease Models, Animal; Eosinophils; Free Radical Scavengers; Gliotoxin; Glutathione; Immunoglobulin E; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukins; Isoprostanes; Lipid Peroxidation; Lung; Lymphocytes; Mice; Mice, Inbred BALB C; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Patulin; Plethysmography, Whole Body; Poisons; Proliferating Cell Nuclear Antigen; Th2 Cells; Translocation, Genetic | 2010 |
The biochemical effectiveness of N-acetylcysteine in experimental spinal cord injury in rats.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Injury Severity Score; Male; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Superoxide Dismutase | 2010 |
N-acetylcysteine protects striated muscle in a model of compartment syndrome.
Topics: Acetylcysteine; Animals; Compartment Syndromes; Disease Models, Animal; Free Radical Scavengers; Muscle Contraction; Muscle, Skeletal; Neutrophil Infiltration; Neutrophils; Oxidative Stress; Peroxidase; Pressure; Rats; Rats, Sprague-Dawley; Respiratory Burst; Time Factors | 2010 |
Spinal levels of nonprotein thiols are related to nociception in mice.
Topics: Acetylcysteine; Acute Disease; Analgesics; Animals; Antimetabolites; Arthritis, Experimental; Behavior, Animal; Buthionine Sulfoximine; Capsaicin; Disease Models, Animal; Female; Foot Injuries; Lipid Peroxidation; Lumbar Vertebrae; Male; Mice; Oxidative Stress; Pain; Spinal Cord; Sulfhydryl Compounds | 2010 |
Beneficial effects of N-acetyl cysteine on pancreas and kidney following experimental pancreatic ischemia-reperfusion in rats.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Glutathione Transferase; Kidney; Pancreas; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury | 2010 |
Protective role of thiol chelators against dimethylmercury induced toxicity in male rats.
Topics: Acetylcysteine; Animals; Brain; Chelating Agents; Disease Models, Animal; Dithiothreitol; Enzymes; Kidney; Lipid Peroxidation; Liver; Male; Mercury Poisoning, Nervous System; Methylmercury Compounds; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2010 |
N-acetyl cysteine promotes angiogenesis and clearance of free oxygen radicals, thus improving wound healing in an alloxan-induced diabetic mouse model of incisional wound.
Topics: Acetylcysteine; Alloxan; Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Free Radical Scavengers; Glutathione; Hydroxyproline; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Nitric Oxide Synthase; Oxidative Stress; Reactive Oxygen Species; Skin; Vascular Endothelial Growth Factors; Wound Healing; Wounds, Penetrating | 2010 |
Inhibition of mitochondrial respiratory chain in the brain of rats after renal ischemia is prevented by N-acetylcysteine and deferoxamine.
Topics: Acetylcysteine; Animals; Cell Respiration; Deferoxamine; Disease Models, Animal; Drug Combinations; Drug Synergism; Electron Transport; Electron Transport Complex I; Free Radical Scavengers; Ischemia; Kidney Diseases; Male; Rats; Rats, Wistar | 2010 |
N-acetylcysteine attenuates noise-induced permanent hearing loss in diabetic rats.
Topics: Acetylcysteine; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Glutathione; Hair Cells, Auditory, Outer; Hearing Loss, Noise-Induced; Male; Rats; Rats, Wistar; Streptozocin | 2010 |
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms.
Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Azoxymethane; Brain Edema; Carcinogens; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Inflammation Mediators; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Oxidative Stress | 2010 |
Ablation of the transcription factor Nrf2 promotes ischemia-induced neovascularization by enhancing the inflammatory response.
Topics: Acetylcysteine; Angiogenic Proteins; Animals; Antioxidants; Capillaries; Cell Adhesion Molecules; Chemokine CCL2; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Femoral Artery; Glutathione; Heme Oxygenase-1; Hindlimb; Inflammation; Inflammation Mediators; Ischemia; Laser-Doppler Flowmetry; Ligation; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Neovascularization, Physiologic; NF-E2-Related Factor 2; Oxidative Stress; Peroxiredoxins; Regional Blood Flow; RNA, Messenger; Superoxides; Thioredoxins; Time Factors; Tumor Necrosis Factor-alpha | 2010 |
N-acetylcysteine prevents vasospasm after subarachnoid hemorrhage.
Topics: Acetylcysteine; Animals; Basilar Artery; Disease Models, Animal; Free Radical Scavengers; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Rabbits; Subarachnoid Hemorrhage; Superoxide Dismutase; Vasospasm, Intracranial | 2010 |
Are intratympanic injections of N-acetylcysteine and methylprednisolone protective against Cisplatin-induced ototoxicity?
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antiviral Agents; Cisplatin; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hearing Disorders; Injections; Methylprednisolone; Severity of Illness Index; Treatment Outcome; Tympanic Membrane | 2010 |
N-acetylcysteine suppresses retinal detachment in an experimental model of proliferative vitreoretinopathy.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Free Radical Scavengers; Humans; Rabbits; Reactive Oxygen Species; Retinal Detachment; Retinal Pigment Epithelium; Vitreoretinopathy, Proliferative; Vitreous Body | 2010 |
Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling.
Topics: Acetylcysteine; Administration, Oral; Animals; Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Diethylnitrosamine; Disease Models, Animal; Liver Neoplasms; Male; Mice; Mice, Knockout; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinases; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction | 2010 |
Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment.
Topics: Acetylcysteine; Administration, Oral; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Cognition Disorders; Disease Models, Animal; Drug Administration Schedule; Gene Knock-In Techniques; Humans; Male; Mice; Mice, Transgenic; Mutation; Oxidative Stress; Presenilin-1; Time Factors | 2010 |
Novel combination therapy for the eradication of Helicobacter pylori infection in a mouse model.
Topics: Acetylcysteine; Amoxicillin; Animals; Anti-Bacterial Agents; Cattle; Colostrum; Disease Models, Animal; Drug Therapy, Combination; Female; Helicobacter Infections; Mice; Mice, Inbred C57BL; Treatment Outcome; Zinc | 2010 |
More than antioxidant: N-acetyl-L-cysteine in a murine model of endometriosis.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Differentiation; Cell Movement; Cell Proliferation; Cytostatic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Endometriosis; Female; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Peritoneal Diseases | 2010 |
S-nitroso-N-acetylcysteine ameliorates ischemia-reperfusion injury in the steatotic liver.
Topics: Acetylcysteine; Animals; Case-Control Studies; Disease Models, Animal; Fatty Liver; Free Radical Scavengers; Liver; Male; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Statistics, Nonparametric; Time Factors | 2010 |
Role of ROS in ischemia-induced lung angiogenesis.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glutathione; Glutathione Disulfide; Ischemia; Lung; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; NF-E2-Related Factor 2; Pulmonary Artery; Reactive Oxygen Species | 2010 |
[Protective effect of N-acetylcysteine on hyperoxic lung injury and its relation with p38 mitogen-activated protein kinase signaling pathway].
Topics: Acetylcysteine; Animals; Disease Models, Animal; Hyperoxia; Lung Injury; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Random Allocation; Rats; Rats, Wistar; Signal Transduction | 2010 |
Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Base Sequence; Cytokines; Disease Models, Animal; DNA Primers; Gene Expression Profiling; Glutamate-Cysteine Ligase; Glutathione; Hepatocytes; Liver; Liver Cirrhosis; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondria, Liver; Oxidative Stress; RNA, Messenger | 2010 |
Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse corneal alkali-burn model.
Topics: Acetylcysteine; Animals; Antioxidants; Benzamides; Blindness; Burns, Chemical; Chemokine CCL2; Corneal Neovascularization; Cyclohexanones; Deuterium Oxide; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Burns; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Microscopy, Fluorescence; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; Superoxide Dismutase; Superoxide Dismutase-1; Vascular Endothelial Growth Factor A | 2011 |
Oxidative stress is not associated with vascular dysfunction in a model of alloxan-induced diabetic rats.
Topics: Acetylcysteine; Alloxan; Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelium, Vascular; Free Radical Scavengers; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Time Factors | 2010 |
Murine models of premature ageing for the study of diet-induced immune changes: improvement of leucocyte functions in two strains of old prematurely ageing mice by dietary supplementation with sulphur-containing antioxidants.
Topics: Acetylcysteine; Aging, Premature; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Female; Leukocytes; Mice; Mice, Inbred BALB C; Sulfur; Thiazolidines | 2010 |
Does 1-(R)-aminoindan possess neuroprotective properties against experimental Parkinson's disease?
Topics: Acetylcysteine; Animals; Catalase; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Humans; Hydrogen Peroxide; Indans; Male; Neuroprotective Agents; Oxidopamine; Parkinsonian Disorders; PC12 Cells; Rats; Rats, Sprague-Dawley | 2011 |
Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiomyopathies; Collagen; Cytokines; Disease Models, Animal; Heart Failure; HSP27 Heat-Shock Proteins; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Reactive Oxygen Species; Receptors, Adrenergic, beta-2; RNA, Messenger; Signal Transduction; Ventricular Remodeling | 2011 |
Suppression of choroidal neovascularization by N-acetyl-cysteine in mice.
Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Blotting, Western; Chemokine CCL2; Chemokine CXCL1; Choroidal Neovascularization; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Free Radical Scavengers; Injections, Intraperitoneal; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
Endotracheal nebulization of N-acetylcysteine increases airway resistance in cats with experimental asthma.
Topics: Acetylcysteine; Aerosols; Airway Resistance; Animals; Antioxidants; Asthma; Bronchoconstriction; Cats; Disease Models, Animal; Drug Delivery Systems; Expectorants; Female; Intubation, Intratracheal; Male; Treatment Outcome | 2011 |
Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Coloring Agents; Disease Models, Animal; Indocyanine Green; Injections, Intravenous; Liver; Male; Mice; Mice, Inbred Strains; Time Factors | 2011 |
Chronic treatment with N-acetylcysteine improves cardiac function but does not prevent progression of cardiomyopathy in Syrian cardiomyopathic hamsters.
Topics: Acetylcholine; Acetylcysteine; Age Factors; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Disease Progression; Echocardiography; Heart Failure; Male; Mesocricetus; Oxidative Stress; Time Factors | 2011 |
Effects of proteasome inhibitors on rat renal fibrosis in vitro and in vivo.
Topics: Acetylcysteine; Actins; Animals; Cells, Cultured; Cysteine Proteinase Inhibitors; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Fibrosis; Kidney Diseases; Leupeptins; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Smad Proteins, Receptor-Regulated; Smad2 Protein; Smad3 Protein; Smad4 Protein; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta; Ureteral Obstruction | 2011 |
Studying protein degradation pathways in vivo using a cranial window-based approach.
Topics: Acetylcysteine; Animals; Blotting, Western; Craniotomy; Cysteine Proteinase Inhibitors; Disease Models, Animal; Humans; Mice; Microscopy, Confocal; Microtomy; Neurodegenerative Diseases; Proteasome Endopeptidase Complex; Ubiquitin | 2011 |
N-(2-mercaptopropionyl)-glycine but not allopurinol prevented cigarette smoke-induced alveolar enlargement in mouse.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Disease Models, Animal; Emphysema; Glycine; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Pulmonary Alveoli; Smoking; Sulfhydryl Compounds; Tobacco Smoke Pollution | 2011 |
N-acetylcysteine suppresses the progression of ventricular remodeling in acute myocarditis: studies in an experimental autoimmune myocarditis (EAM) model.
Topics: Acetylcysteine; Acute Disease; Animals; Autoimmune Diseases; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Free Radical Scavengers; Injections, Intraperitoneal; Myocarditis; Oxidative Stress; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Ventricular Remodeling | 2011 |
Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease.
Topics: Acetylcysteine; Animals; Benzamides; Brain; Case-Control Studies; Cell Line; Disease Models, Animal; Dopamine; Drug Administration Schedule; Free Radical Scavengers; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Imatinib Mesylate; Immunoprecipitation; Male; Metalloporphyrins; Mice; Mice, Inbred C57BL; MPTP Poisoning; Oxidative Stress; Peptide Elongation Factors; Phosphorylation; Piperazines; Polyethylene Glycols; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; RNA, Small Interfering; Statistics, Nonparametric; Transfection; Tumor Suppressor Proteins; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination | 2011 |
Ammonium chloride and tunicamycin are novel toxins for dopaminergic neurons and induce Parkinson's disease-like phenotypes in medaka fish.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Disease Models, Animal; Dopamine; Nerve Tissue Proteins; Neurons; Neurotoxins; Oryzias; Parkinsonian Disorders; Phenotype; Substantia Nigra; Tunicamycin | 2010 |
Effect of N-acetylcysteine on vasospasm in subarachnoid hemorrhage.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Male; Rats; Rats, Wistar; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2010 |
Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Disease Progression; Male; Mental Disorders; Motor Activity; Parkinson Disease, Secondary; Prognosis; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2011 |
Combined effect of N-acetyl cysteine, zinc, and selenium against chronic dimethylmercury-induced oxidative stress: a biochemical and histopathological approach.
Topics: Acetylcysteine; Animals; Antioxidants; Cytochrome P-450 Enzyme System; Disease Models, Animal; Drug Interactions; Lipid Peroxidation; Male; Mercury Poisoning; Methylmercury Compounds; Microsomes, Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sodium Selenite; Zinc Acetate | 2011 |
Protective effect of N-acetylcysteine on bisphenol A-induced cognitive dysfunction and oxidative stress in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Benzhydryl Compounds; Brain; Cognition Disorders; Disease Models, Animal; Drug Antagonism; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory; Oxidative Stress; Phenols; Rats; Rats, Wistar; Space Perception | 2011 |
N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse.
Topics: Acetylcysteine; Age Factors; Aged; Analysis of Variance; Animals; Blotting, Western; Cell Count; Cell Death; Disease Models, Animal; Dopamine; Excitatory Amino Acid Transporter 3; Humans; Immunohistochemistry; Mice; Mice, Knockout; Microglia; Motor Activity; Neurons; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase | 2011 |
N-Acetylcysteine promotes long-term survival of cones in a model of retinitis pigmentosa.
Topics: Acetylcysteine; Administration, Oral; Administration, Topical; Animals; Antioxidants; Catalase; Cell Survival; Disease Models, Animal; Electroretinography; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Photic Stimulation; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Retinitis Pigmentosa; Superoxide Dismutase; Superoxides; Time Factors; Up-Regulation | 2011 |
Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells.
Topics: Acetylcysteine; Actins; Animals; Binding Sites; Carotid Artery Injuries; Cells, Cultured; Chromatin Immunoprecipitation; Collagen; Cysteine Proteinase Inhibitors; Disease Models, Animal; DNA Polymerase II; Gels; Gene Expression Regulation; Genotype; Humans; Leupeptins; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Phenotype; Phosphorylation; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Serine; Serum Response Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection; Vasoconstriction | 2011 |
Influence of N-acetylcysteine against dimethylnitrosamine induced hepatotoxicity in rats.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Disease Models, Animal; Free Radical Scavengers; Lipid Peroxidation; Liver; Liver Function Tests; Male; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar | 2011 |
Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antiparasitic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hyperalgesia; Male; Mitochondria; Nerve Growth Factor; Oligomycins; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley | 2011 |
A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice.
Topics: Acetylcysteine; Animals; Apolipoproteins E; bcl-2-Associated X Protein; Dietary Fats; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Free Radical Scavengers; Hepatocytes; Lipogenesis; Male; MAP Kinase Kinase 4; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Selenomethionine | 2011 |
N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and d-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder.
Topics: Acetylcysteine; Animals; Bipolar Disorder; Brain; Corpus Striatum; Cyclohexanones; Dextroamphetamine; Disease Models, Animal; Frontal Lobe; Glutathione; Male; Rats; Rats, Sprague-Dawley; Schizophrenia | 2011 |
L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Male; Mice; Mice, Inbred C57BL; Neutrophils; NG-Nitroarginine Methyl Ester; Nicotiana; Nitric Oxide; Oxidants; Oxidative Stress; Pulmonary Emphysema; Smoke; Smoking | 2011 |
An in vivo and in vitro study on the protective effects of N-acetylcysteine on mitochondrial dysfunction in isoproterenol treated myocardial infarcted rats.
Topics: Acetylcysteine; Animals; Antioxidants; Creatine Kinase; Data Interpretation, Statistical; Disease Models, Animal; In Vitro Techniques; Isoproterenol; Lipid Peroxidation; Male; Microscopy, Electron, Transmission; Mitochondria, Heart; Mitochondrial Diseases; Myocardial Infarction; Rats; Rats, Wistar | 2013 |
Low-dose D-methionine and N-acetyl-L-cysteine for protection from permanent noise-induced hearing loss in chinchillas.
Topics: Acetylcysteine; Animals; Auditory Threshold; Chinchilla; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Female; Hearing Loss, Noise-Induced; Injections, Intraperitoneal; Methionine; Random Allocation; Reference Values; Treatment Outcome | 2011 |
Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart.
Topics: Acetylcysteine; Animals; Ascorbic Acid; Biopterins; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2011 |
[The effect of N-acetylcysteine on hepatic function in patients suffering from mechanical jaundice of cholelithic etiology].
Topics: Acetylcysteine; Animals; Disease Models, Animal; Jaundice, Obstructive; Liver; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2011 |
Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis.
Topics: Acetylcysteine; Alcoholism; Animals; Cytokines; Disease Models, Animal; Fatty Liver, Alcoholic; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley | 2011 |
Davallialactone protects against adriamycin-induced cardiotoxicity in vitro and in vivo.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Blotting, Western; Cardiomyopathies; Caspase 3; Cell Line; Cell Survival; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; JNK Mitogen-Activated Protein Kinases; Lactones; Male; Mice; Mice, Inbred BALB C; Myocytes, Cardiac; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Superoxide Dismutase; Time Factors | 2012 |
Protective effect of pristane on experimental autoimmune uveitis.
Topics: Acetylcysteine; Animals; Autoimmunity; Cell Line; Disease Models, Animal; Eye; Eye Proteins; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Immunization; Immunoglobulin G; Interleukin-17; Mice; Mice, Inbred C57BL; Oxidative Stress; Peptide Fragments; Phytol; Retinol-Binding Proteins; Terpenes; Uveitis | 2011 |
Reactive oxygen species-mediated mitochondrial dysfunction is involved in apoptosis in human nasopharyngeal carcinoma CNE cells induced by Selaginella doederleinii extract.
Topics: Acetylcysteine; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Caspases; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Disease Models, Animal; Female; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Selaginellaceae | 2011 |
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia | 2012 |
[Content of chaperon Hsp70 in dopaminergic neurons of the black substance increases in proteasome dysfunstion].
Topics: Acetylcysteine; Aging; Animals; Bacterial Proteins; Biotin; Blotting, Western; Catheterization; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Microinjections; Microscopy, Confocal; Neurons; Parkinson Disease; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Wistar; Substantia Nigra; Tyrosine 3-Monooxygenase; Ubiquitin; Up-Regulation | 2011 |
Antioxidant N-acetyl cysteine reverses cigarette smoke-induced myocardial infarction by inhibiting inflammation and oxidative stress in a rat model.
Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; Cotinine; Cytokines; Disease Models, Animal; DNA Primers; Echocardiography; Inflammation; Myocardial Infarction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Smoke | 2012 |
Multidrug strategies are effective in the treatment of severe experimental pancreatitis.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Dextrans; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats | 2012 |
Protective effects of zinc, pentoxifylline, and N-acetylcysteine in an animal model of laparoscopy-induced ischemia/reperfusion injury of the small intestine.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Intestine, Small; Laparoscopy; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Zinc | 2011 |
Hypercholesterolemia and oxidative stress inhibit endothelial cell healing after arterial injury.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Carotid Artery Injuries; Carotid Artery, Common; Cell Proliferation; Disease Models, Animal; Endothelial Cells; Hypercholesterolemia; Male; Mice; Mice, Inbred C57BL; Oxidants; Oxidative Stress; Paraquat; Time Factors; Wound Healing | 2012 |
Identification of proteins responding to adrenergic receptor subtype-specific hypertrophy in cardiomyocytes by proteomic approaches.
Topics: Acetylcysteine; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Isoproterenol; Myocytes, Cardiac; Oxidative Stress; Phenylephrine; Phosphorylation; Proteins; Proteomics; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2011 |
Endotoxin-induced acute lung injury is dependent upon oxidative response.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Catalase; Cytokines; Disease Models, Animal; Gene Expression; Glutathione; Lipopolysaccharides; Lung; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxidase; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2011 |
The role of N-acetyl-cysteine in the lung remote injury after hepatic ischemia and reperfusion in rabbits.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Glucose; Infusions, Intravenous; Liver; Lung Injury; Male; Rabbits; Random Allocation; Reperfusion Injury; Time Factors | 2012 |
Relationship between ischemia/reperfusion injury and the stimulus of fibrogenesis in an experimental model: comparison among different preservation solutions.
Topics: Acetylcysteine; Adenosine; Alanine Transaminase; Allopurinol; Animals; Aspartate Aminotransferases; Biomarkers; Catalase; Disease Models, Animal; Fructosediphosphates; Glutathione; Insulin; L-Lactate Dehydrogenase; Liver; Liver Cirrhosis; Liver Transplantation; Male; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Time Factors; Transforming Growth Factor beta1 | 2011 |
Paclitaxel therapy potentiates cold hyperalgesia in streptozotocin-induced diabetic rats through enhanced mitochondrial reactive oxygen species production and TRPA1 sensitization.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Cold Temperature; Diabetes Mellitus, Experimental; Disease Models, Animal; Ganglia, Spinal; Glucose Tolerance Test; Glutathione Peroxidase; Hydrogen Peroxide; Hyperalgesia; Hypoxanthine Phosphoribosyltransferase; Male; Microscopy, Electron, Transmission; Mitochondria; Paclitaxel; Pain Measurement; Pain Threshold; Phospholipid Hydroperoxide Glutathione Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sciatic Nerve; Sensory Receptor Cells; Streptozocin; Time Factors; TRPA1 Cation Channel; TRPC Cation Channels | 2012 |
Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Auditory Threshold; Biomarkers; Chinchilla; Cochlear Nucleus; Disease Models, Animal; Drug Therapy, Combination; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Imines; Interneurons; Microscopy, Electron, Transmission; Neuronal Plasticity; Phenols; Protein Precursors; Synapses; Synaptic Transmission; Synaptophysin; Time Factors | 2012 |
Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Antioxidants; Biophysics; Biotinylation; Calpain; Cell Line, Transformed; Cognition Disorders; Conditioning, Psychological; Cyclin-Dependent Kinase 5; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Fear; Hippocampus; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Peptide Fragments; Presenilin-1; Protein Kinase C-delta; Receptors, Metabotropic Glutamate; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Social Isolation; Time Factors; Transfection | 2012 |
Antifibrotic and antioxidant effects of N-acetylcysteine in an experimental cholestatic model.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Catalase; Cholestasis; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Fibrosis; Glutathione; Inflammation Mediators; Lipid Peroxidation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar | 2012 |
N-acetylcysteine prevents pulmonary edema and acute kidney injury in rats with sepsis submitted to mechanical ventilation.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Cecum; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Lung; Male; Neutrophils; Oxidative Stress; Pulmonary Edema; Rats; Rats, Wistar; Respiration, Artificial; Sepsis; Sodium Channels; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2 | 2012 |
Antioxidant treatment reduces blast-induced cochlear damage and hearing loss.
Topics: Acetylcysteine; Animals; Antioxidants; Auditory Threshold; Benzenesulfonates; Cochlea; Disease Models, Animal; Drug Therapy, Combination; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory, Inner; Hair Cells, Auditory, Outer; Hearing Loss, Noise-Induced; Male; Otoacoustic Emissions, Spontaneous; Rats; Rats, Long-Evans; Time Factors | 2012 |
N-acetylcysteine attenuates ventilator-induced lung injury in an isolated and perfused rat lung model.
Topics: Acetylcysteine; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Disease Models, Animal; Free Radical Scavengers; Interleukin-1beta; Male; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tidal Volume; Tumor Necrosis Factor-alpha; Ventilator-Induced Lung Injury | 2012 |
Pretreatment with pentoxifylline and N-acetylcysteine in liver ischemia reperfusion-induced renal injury.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Free Radical Scavengers; Liver; Male; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome | 2012 |
Effect of N-acetylcysteine on lung injury induced by skeletal muscle ischemia-reperfusion. Histopathlogical study in rat model.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Lung; Lung Injury; Male; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Treatment Outcome | 2012 |
N-acetylcysteine pretreatment ameliorates mercuric chloride-induced oxidative renal damage in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Chemoprevention; Disease Models, Animal; Glucose-6-Phosphatase; Glutathione; Injections, Intraperitoneal; Kidney; Lipid Peroxidation; Male; Malondialdehyde; Mercuric Chloride; Mercury; Mercury Poisoning; Oxidation-Reduction; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase | 2010 |
Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy.
Topics: Acetophenones; Acetylcysteine; Animals; Animals, Genetically Modified; Antioxidants; Behavior, Animal; Disease Models, Animal; Enzyme Inhibitors; Humans; Indomethacin; Larva; Microarray Analysis; Microscopy, Electron, Transmission; Mitochondria; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Diseases; Mutation; Oxidative Stress; Ryanodine Receptor Calcium Release Channel; Zebrafish | 2012 |
N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus.
Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Hippocampus; Male; Methylmercury Compounds; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Pregnancy; Rats; Spectrophotometry, Atomic; Thymidine; Tritium | 2012 |
N-acetylcysteine may prevent severe intestinal damage in necrotizing enterocolitis.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Biomarkers; Caspases; Colon; Disease Models, Animal; Drug Administration Schedule; Enterocolitis, Necrotizing; Free Radical Scavengers; Ileum; In Situ Nick-End Labeling; Kaplan-Meier Estimate; Lipid Peroxidation; Oxidants; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Antioxidant administration prevents memory impairment in an animal model of maple syrup urine disease.
Topics: Acetylcysteine; Amino Acids, Branched-Chain; Animals; Antioxidants; Deferoxamine; Disease Models, Animal; Male; Maple Syrup Urine Disease; Memory; Memory Disorders; Rats; Rats, Wistar | 2012 |
N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Methoxyhydroxyphenylglycol; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Staurosporine | 2012 |
Evaluation of N-acetylcysteine treatment in acute pancreatitis-induced lung injury.
Topics: Acetylcysteine; Amylases; Animals; Chemokine CCL2; Chemokine CXCL1; Disease Models, Animal; Free Radical Scavengers; Lung; Lung Injury; Male; Pancreatitis; Peroxidase; Rats; Rats, Wistar; RNA, Messenger; Taurocholic Acid | 2012 |
Anti-parkinsonian effects of Nurr1 activator in ubiquitin-proteasome system impairment induced animal model of Parkinson's disease.
Topics: Acetylcysteine; Animals; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Microglia; Motor Activity; Neostriatum; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinsonian Disorders; Proteasome Endopeptidase Complex; Real-Time Polymerase Chain Reaction; RNA, Messenger; Substantia Nigra; Transcriptional Activation; Vesicular Monoamine Transport Proteins | 2012 |
Protective effects of N-acetylcysteine amide (NACA) on gentamicin-induced apoptosis in LLC-PK1 cells.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA; Flow Cytometry; Free Radical Scavengers; Gene Expression Regulation; Gentamicins; LLC-PK1 Cells; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Polymerase Chain Reaction; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Swine | 2012 |
Correlation of nitric oxide levels in the cerebellum and spinal cord of experimental autoimmune encephalomyelitis rats with clinical symptoms.
Topics: Acetylcysteine; Animals; Cerebellum; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; Myelin Basic Protein; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spinal Cord | 2012 |
Biomedicine. Nanoparticle treatment reverses cerebral palsy in rabbits.
Topics: Acetylcysteine; Animals; Animals, Newborn; Astrocytes; Brain; Cerebral Palsy; Dendrimers; Disease Models, Animal; Microglia; Neuroprotective Agents; Rabbits | 2012 |
Pharmacological and biochemical analysis of interactions between N-acetylcysteine and some antiepileptic drugs on experimental seizures in mice.
Topics: Acetylcysteine; Alanine Transaminase; Alkaline Phosphatase; Animals; Anticonvulsants; Aspartate Aminotransferases; Calcium; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Electroshock; Exploratory Behavior; Female; Glutathione; Hand Strength; Male; Malondialdehyde; Mice; Seizures | 2012 |
Effect of melatonin and n-acetylcysteine on hepatic injury in rat induced by methanol intoxication: a comparative study.
Topics: Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Liver; Male; Melatonin; Methanol; Microscopy, Electron; Protective Agents; Rats; Rats, Wistar; Time Factors | 2012 |
Proteinuria elevates asymmetric dimethylarginine levels via protein arginine methyltransferase-1 overexpression in a rat model of nephrotic syndrome.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Cells, Cultured; Disease Models, Animal; Doxorubicin; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Kidney Tubules, Proximal; Male; Nephrotic Syndrome; Oxidative Stress; Protein-Arginine N-Methyltransferases; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin; Time Factors | 2012 |
Immunohistopathological changes in murine Schistosomiasis mansoni under the influence of N-acetyl-L-cysteine.
Topics: Acetylcysteine; Administration, Oral; Animals; Anthelmintics; Anti-Inflammatory Agents; Disease Models, Animal; Female; Granuloma; Histocytochemistry; Immunohistochemistry; Liver; Male; Mice; Praziquantel; Schistosomiasis mansoni; Treatment Outcome | 2012 |
Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model.
Topics: Acetylcysteine; Air Pollution, Indoor; Animals; Asthma; Dendritic Cells; Disease Models, Animal; Female; Floors and Floorcoverings; Glycols; Interleukin-12; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Pneumonia; Polyvinyl Chloride; Pyrrolidinones; Th2 Cells; Volatile Organic Compounds | 2012 |
N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats.
Topics: Acetylcysteine; Animals; Antidepressive Agents; Antioxidants; Brain; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Imipramine; Immobility Response, Tonic; Male; Motor Activity; Olfactory Bulb; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Thiol oxidation and altered NR2B/NMDA receptor functions in in vitro and in vivo pilocarpine models: implications for epileptogenesis.
Topics: Acetylcysteine; Animals; Apoptosis; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagonists; Hippocampus; Male; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Pilocarpine; Piperidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Compounds | 2013 |
Anti-inflammatory treatment in dysfunction of pulmonary surfactant in meconium-induced acute lung injury.
Topics: Acetylcysteine; Acute Lung Injury; Aminophylline; Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Budesonide; Dexamethasone; Disease Models, Animal; Humans; Imidazoles; Infant, Newborn; Leukocyte Count; Lung; Meconium; Meconium Aspiration Syndrome; Neutrophils; Oxidative Stress; Phosphodiesterase Inhibitors; Pulmonary Edema; Pulmonary Surfactants; Pyridones; Rabbits | 2013 |
CFTR is involved in the fine tuning of intracellular redox status: physiological implications in cystic fibrosis.
Topics: Acetylcysteine; Animals; Carbonic Anhydrases; Cell Hypoxia; Cell Line; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Glutathione; Green Fluorescent Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Space; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Models, Biological; Mutation; Osmolar Concentration; Oxidation-Reduction; Protein Stability; Protein Structure, Tertiary; Reactive Oxygen Species | 2012 |
Oxidative stress as a therapeutic target in globoid cell leukodystrophy.
Topics: Acetylcysteine; Animals; Antioxidants; Bone Marrow Transplantation; Disease Models, Animal; Immunohistochemistry; Leukodystrophy, Globoid Cell; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress | 2012 |
Effect of N-acetylcysteine on pulmonary cell death in a controlled hemorrhagic shock model in rats.
Topics: Acetylcysteine; Animals; Caspase 3; Cell Death; Disease Models, Animal; Fluid Therapy; In Situ Nick-End Labeling; Lung; Lung Injury; Male; Rats; Resuscitation; Shock, Hemorrhagic; Time Factors | 2012 |
An effective antioxidant drug on prevention of the necrosis of zone of stasis: N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; Burns; Disease Models, Animal; Male; Necrosis; Rats; Rats, Sprague-Dawley | 2013 |
Sodium butyrate potentiates carbon tetrachloride-induced acute liver injury in mice.
Topics: Acetylcysteine; Animals; Butyrates; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histone Deacetylases; Liver; Male; Mice; Oxidative Stress; Thioctic Acid | 2012 |
Pulmonary impact of N-acetylcysteine in a controlled hemorrhagic shock model in rats.
Topics: Acetylcysteine; Acute Lung Injury; Animals; Antioxidants; Disease Models, Animal; Fluid Therapy; Interleukin-10; Interleukin-6; Lung; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic | 2013 |
Effect of pirfenidone on pulmonary fibrosis due to paraquat poisoning in rats.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Disease Models, Animal; Herbicides; Injections, Intraperitoneal; Injections, Intravenous; Life Expectancy; Male; Paraquat; Pulmonary Fibrosis; Pyridones; Rats; Rats, Wistar; Survival Rate; Vitamin E | 2012 |
Lesson from acute experimental pancreatitis: multidrug strategies is effective than single-target therapy.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Gabexate; Humans; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreas; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats; Survival Analysis; Survival Rate; Treatment Outcome | 2012 |
Antioxidant effects of N-acetylcysteine in a neonatal rat model of necrotizing enterocolitis.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Disease Models, Animal; Drug Administration Schedule; Enterocolitis, Necrotizing; Injections, Intraperitoneal; Intestinal Mucosa; Malondialdehyde; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2012 |
Inhibition of NF-κB activation by 4-hydroxynonenal contributes to liver injury in a mouse model of alcoholic liver disease.
Topics: Acetylcysteine; Aldehydes; Animals; Bezafibrate; Caspases; Cell Death; Cytoprotection; Disease Models, Animal; Enzyme Activation; Ethanol; Hep G2 Cells; Hepatocytes; Humans; I-kappa B Proteins; JNK Mitogen-Activated Protein Kinases; Liver; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Time Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2012 |
Laboratory evidence of sustained chronic inflammatory reaction in retinitis pigmentosa.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Count; Cell Survival; Chemokine CCL2; Chemokine CCL5; Disease Models, Animal; Gene Expression Regulation; Immunohistochemistry; In Situ Nick-End Labeling; Interleukin-1beta; Mice; Mice, Inbred C57BL; Microglia; Photoreceptor Cells, Vertebrate; Real-Time Polymerase Chain Reaction; Retinitis Pigmentosa; RNA, Messenger; Tumor Necrosis Factor-alpha | 2013 |
N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycin-induced pulmonary fibrosis in rats.
Topics: Acetylcysteine; Actins; Animals; Antibiotics, Antineoplastic; Bleomycin; Collagen; Disease Models, Animal; Down-Regulation; Free Radical Scavengers; Glutathione; Idiopathic Pulmonary Fibrosis; Lung; Male; Protein-Lysine 6-Oxidase; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2012 |
Proliferative activity in ischemia/reperfusion injury in hepatectomized mice: effect of N-acetylcysteine.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Cell Proliferation; Cytoprotection; Disease Models, Animal; Hepatectomy; Immunohistochemistry; Liver; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Necrosis; Proliferating Cell Nuclear Antigen; Reperfusion Injury; Time Factors | 2012 |
N-acetylcysteine lock solution prevents catheter-associated bacteremia in rabbits.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Catheters, Indwelling; Central Venous Catheters; Colony Count, Microbial; Disease Models, Animal; Female; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Time Factors | 2012 |
Chronic administration of branched-chain amino acids impairs spatial memory and increases brain-derived neurotrophic factor in a rat model.
Topics: Acetylcysteine; Amino Acids, Branched-Chain; Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Deferoxamine; Disease Models, Animal; Hippocampus; Male; Maple Syrup Urine Disease; Memory; Memory Disorders; Oxidative Stress; Protein Precursors; Rats; Rats, Wistar; RNA, Messenger | 2013 |
Using a novel in vivo model to study the function of nuclear factor kappa B in cerebral ischemic injury.
Topics: Acetylcysteine; Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; I-kappa B Proteins; Male; Mutant Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Rats, Wistar; Transcription Factor RelA | 2012 |
Monosodium iodoacetate induces apoptosis via the mitochondrial pathway involving ROS production and caspase activation in rat chondrocytes in vitro.
Topics: Acetylcysteine; Animals; Apoptosis; Cartilage, Articular; Caspase 3; Cell Survival; Chondrocytes; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Femur Head; Iodoacetates; Male; Membrane Potential, Mitochondrial; Mitochondria; Osteoarthritis; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
Modulatory effects of curcumin and green tea extract against experimentally induced pulmonary fibrosis: a comparison with N-acetyl cysteine.
Topics: Acetylcysteine; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Camellia sinensis; Curcumin; Cyclophosphamide; Dietary Supplements; Disease Models, Animal; Inflammation Mediators; Lipid Peroxidation; Lung; Male; Plant Extracts; Plant Leaves; Protective Agents; Pulmonary Fibrosis; Rats; Rats, Wistar; Tea | 2012 |
Reduction in phencyclidine induced sensorimotor gating deficits in the rat following increased system xc⁻ activity in the medial prefrontal cortex.
Topics: Acetylcysteine; Amino Acid Transport System y+; Amino Acid Transport Systems, Acidic; Animals; Benzoates; Disease Models, Animal; Dose-Response Relationship, Drug; Gait Disorders, Neurologic; Glycine; In Situ Hybridization; Male; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reflex, Startle; RNA, Messenger; Schizophrenia; Sensory Gating | 2013 |
N-acetylcysteine administration is associated with reduced activation of NF-kB and preserves lung dendritic cells function in a zymosan-induced generalized inflammation model.
Topics: Acetylcysteine; Animals; Apoptosis; Cytokines; Dendritic Cells; Disease Models, Animal; Enzyme Activation; Histocompatibility Antigens Class II; Inflammation; Lung; Male; Mice; NF-kappa B; Receptors, CCR5; Receptors, CCR7; Respiratory Function Tests; RNA, Messenger; Zymosan | 2013 |
BMP2 is superior to BMP4 for promoting human muscle-derived stem cell-mediated bone regeneration in a critical-sized calvarial defect model.
Topics: Acetylcysteine; Adult; Aged, 80 and over; Animals; Biomarkers; Bone Diseases; Bone Morphogenetic Protein 4; Bone Regeneration; Cell Survival; Cells, Cultured; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Nude; Mice, SCID; Muscle, Skeletal; Osteogenesis; Stem Cell Transplantation; Stem Cells; Transplantation, Heterologous; Young Adult | 2013 |
Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy.
Topics: Acetylcysteine; Adenosine Triphosphate; Adrenoleukodystrophy; Age Factors; Analysis of Variance; Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Brain; Buthionine Sulfoximine; Cell Death; Chromatin; Cyclophilins; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Galactose; Gene Expression Regulation; Glucose; Glutathione; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Neuroprotective Agents; Oligopeptides; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Permeability; Reactive Oxygen Species; Thioctic Acid; Time Factors; Tubulin; Vitamin E | 2012 |
N-acetylcysteine exerts therapeutic action in a rat model of allergic rhinitis.
Topics: Acetylcysteine; Administration, Intranasal; Allergens; Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Disease Models, Animal; Male; Nasal Mucosa; Nitric Oxide Synthase Type II; Ovalbumin; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Tumor Necrosis Factor-alpha | 2013 |
Effect of N-acetylcysteine on acute allograft rejection after rat lung transplantation.
Topics: Acetylcysteine; Acute Disease; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Disease Models, Animal; Free Radical Scavengers; Graft Rejection; Immunity, Innate; Immunohistochemistry; Lung Transplantation; Macrophages, Alveolar; Male; Rats; Rats, Inbred BN; Rats, Inbred Lew; Receptors, Cell Surface; Receptors, Scavenger; Reperfusion Injury; T-Lymphocytes; Transplantation, Homologous | 2013 |
Effects of N-acetylcysteine on macrophage and lymphocyte functions in a mouse model of premature ageing.
Topics: Acetylcysteine; Aging, Premature; Animals; Disease Models, Animal; Female; Lymphocytes; Macrophages; Mice; Reactive Oxygen Species | 2002 |
A diet supplemented with thiolic anti-oxidants improves leucocyte function in two strains of prematurely ageing mice.
Topics: Acetylcysteine; Aging, Premature; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Female; Leukocytes; Mice; Mice, Inbred BALB C; Species Specificity; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 2002 |
Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury.
Topics: Acetylcysteine; Animals; Creatine Kinase; Creatine Kinase, MB Form; Cysteine Endopeptidases; Disease Models, Animal; Enzyme Inhibitors; Female; Isoenzymes; Male; Multienzyme Complexes; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Proteasome Endopeptidase Complex; Swine; Troponin I | 2003 |
[The influence of N-acetyl-L-cysteine on pulmonary injury and oxygen stress after smoke inhalation injury].
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Free Radical Scavengers; Glutathione; Hydrogen Peroxide; Leukocytes; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Smoke Inhalation Injury | 2002 |
Timing of supplementation with the antioxidant N-acetyl-L-cysteine reduces tumor multiplicity in novel, cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) transgenic mice but has no impact on malignant progression.
Topics: Acetylcysteine; Animals; Antioxidants; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cross-Over Studies; Dietary Supplements; Disease Models, Animal; Female; Free Radical Scavengers; Genes, ras; Linear Models; Male; Mice; Mice, Transgenic; Sarcoma; Skin Neoplasms; Survival Rate; Time Factors | 2002 |
Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.
Topics: Acetylcysteine; Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Collagen; Cysteine; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Inflammation; Leukocyte Count; Matrix Metalloproteinase 9; Mice; Mice, Inbred Strains; Neutrophils; Pulmonary Fibrosis; Severity of Illness Index; Time Factors | 2003 |
Idiopathic pneumonia after marrow transplantation: when are antioxidants effective?
Topics: Acetylcysteine; Animals; Antioxidants; Bone Marrow Transplantation; Disease Models, Animal; Mice; Pneumonia; Postoperative Complications | 2002 |
Idiopathic pneumonia syndrome after syngeneic bone marrow transplant in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Flow Cytometry; Mice; Oxidative Stress; Pneumonia; Postoperative Complications; Pulmonary Alveoli | 2002 |
Effects of N-acetylcysteine on myoglobinuric-acute renal failure in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Cryoprotective Agents; Disease Models, Animal; Free Radical Scavengers; Glycerol; Hypertonic Solutions; Injections, Intraperitoneal; Kidney; Myoglobinuria; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Time Factors | 2002 |
Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney.
Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Disease Models, Animal; Drug Therapy, Combination; Glutathione Peroxidase; Glycopeptides; Ischemic Preconditioning; Kidney; Male; Nitroprusside; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Time Factors | 2002 |
Attenuation of ischemia/reperfusion induced MAP kinases by N-acetyl cysteine, sodium nitroprusside and phosphoramidon.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Glycopeptides; Immunohistochemistry; Ischemia; Ischemic Preconditioning; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Nitroprusside; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Survival Rate; Time Factors; Transcription Factor AP-1 | 2002 |
Effects of antioxidant pretreatment on the survival of embryonic dopaminergic neurons in vitro and following grafting in an animal model of Parkinson's disease.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Chromans; Disease Models, Animal; Dopamine; Drug Combinations; Female; Fetus; Glutathione; Graft Survival; Male; Neurons; Oxidopamine; Parkinsonian Disorders; Piperazines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stem Cell Transplantation; Stem Cells; Substantia Nigra | 2002 |
The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice.
Topics: Acetylcysteine; Age Factors; Amyloid beta-Peptides; Animals; Antioxidants; Appetitive Behavior; Behavior, Animal; Blood-Brain Barrier; Brain; Cognition; Disease Models, Animal; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred Strains; Mice, Neurologic Mutants; Oxidative Stress; Specific Pathogen-Free Organisms; Thioctic Acid; Treatment Outcome | 2003 |
Protection from noise-induced lipid peroxidation and hair cell loss in the cochlea.
Topics: Acetylcysteine; Acoustic Stimulation; Animals; Auditory Threshold; Cell Count; Cochlea; Dinoprost; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Evoked Potentials, Auditory, Brain Stem; F2-Isoprostanes; Free Radical Scavengers; Guinea Pigs; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Noise; Piperidines; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2003 |
Oral N-acetylcysteine attenuates the rat pulmonary inflammatory response to antigen.
Topics: Acetylcysteine; Administration, Oral; Airway Resistance; Allergens; Analysis of Variance; Animals; Asthma; Base Sequence; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation Mediators; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Molecular Sequence Data; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Probability; Rats; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
In vivo antioxidant treatment protects against bleomycin-induced lung damage in rats.
Topics: Acetonitriles; Acetylcysteine; Animals; Antioxidants; Biomarkers; Bleomycin; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydroxyproline; Immunohistochemistry; Lung; Macrophages, Alveolar; Male; NF-kappa B; Organ Size; Oxidative Stress; Pneumonia; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors; Trityl Compounds | 2003 |
A distinct death mechanism is induced by 1-methyl-4-phenylpyridinium or by 6-hydroxydopamine in cultured rat cortical neurons: degradation and dephosphorylation of tau.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Cell Culture Techniques; Cerebral Cortex; Cysteine Proteinase Inhibitors; Disease Models, Animal; Drug Interactions; Free Radical Scavengers; Microscopy, Electron; Mitochondria; Neurons; Oxidopamine; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; tau Proteins; Time Factors | 2003 |
The protective effect of N-acetylcysteine on apoptotic lung injury in cecal ligation and puncture-induced sepsis model.
Topics: Acetylcysteine; Animals; Apoptosis; Cecum; Disease Models, Animal; Intestinal Perforation; Ligation; Lipid Peroxidation; Lung; Lung Diseases; Male; Malondialdehyde; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Resuscitation; Systemic Inflammatory Response Syndrome | 2003 |
Effect of N-acetylcysteine on microcirculation of mucosa in rat ileum in a model of intestinal inflammation.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Indomethacin; Inflammation; Intestinal Mucosa; Intestine, Small; Male; Microcirculation; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Statistics, Nonparametric | 2003 |
Attenuation of ischemia/reperfusion injury by N-acetylcysteine in a rat hind limb model.
Topics: Acetylcysteine; Animals; Bicarbonates; Constriction; Creatine Kinase; Dimethyl Sulfoxide; Disease Models, Animal; Free Radical Scavengers; Hindlimb; L-Lactate Dehydrogenase; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiobarbituric Acid Reactive Substances | 2003 |
Redox regulation of neuronal migration in a Down Syndrome model.
Topics: Acetylcysteine; Animals; Chemotaxis; Disease Models, Animal; Dithiothreitol; Down Syndrome; Fetus; Glutamic Acid; Mice; N-Methylaspartate; Neurons; Oxidation-Reduction; Oxidative Stress; Receptors, N-Methyl-D-Aspartate; Trisomy | 2003 |
Meningitis-associated hearing loss: protection by adjunctive antioxidant therapy.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Audiometry; Ceftriaxone; Cell Count; Cochlea; Disease Models, Animal; Drug Interactions; Evans Blue; Evoked Potentials, Auditory, Brain Stem; Hearing Loss; Labyrinthitis; Male; Meningitis, Pneumococcal; Metalloporphyrins; Peroxynitrous Acid; Rats; Rats, Wistar; Spiral Ganglion; Time Factors | 2003 |
Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly.
Topics: Acetylcysteine; Animals; Apolipoproteins B; Cells, Cultured; Cysteine Endopeptidases; Diabetes Mellitus; Disease Models, Animal; Gerbillinae; Hepatocytes; Hypercholesterolemia; Hyperinsulinism; Hypertriglyceridemia; Insulin; Insulin Resistance; Leupeptins; Lipoproteins, VLDL; Liver; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex | 2004 |
N-acetylcysteine prevents intra-acinar oxygen free radical production in pancreatic duct obstruction-induced acute pancreatitis.
Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Male; Pancreas; Pancreatic Ducts; Pancreatitis; Rats; Rats, Wistar | 2003 |
Birth-related genomic and transcriptional changes in mouse lung. Modulation by transplacental N-acetylcysteine.
Topics: Acetylcysteine; Animals; Animals, Newborn; Disease Models, Animal; Female; Free Radical Scavengers; Gene Expression Regulation, Developmental; Genomics; Lung; Maternal-Fetal Exchange; Mice; Pregnancy; Transcription, Genetic | 2003 |
The antioxidant N-acetylcysteine preserves myocardial function and diminishes oxidative stress after cardioplegic arrest.
Topics: Acetylcysteine; Animals; Antioxidants; Cardiopulmonary Bypass; Disease Models, Animal; Dogs; Female; Heart Arrest, Induced; Heart Function Tests; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Oxidative Stress; Probability; Random Allocation; Reference Values; Risk Assessment; Sensitivity and Specificity; Ventricular Function, Left | 2003 |
Bone marrow chemoprotection without compromise of chemotherapy efficacy in a rat brain tumor model.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Bone Marrow; Brain Neoplasms; Chemoprevention; Disease Models, Animal; Drug Interactions; Inactivation, Metabolic; Protective Agents; Rats; Rats, Long-Evans; Sulfhydryl Compounds; Treatment Outcome | 2004 |
N-acetylcysteine attenuates lung injury in a rodent model of fracture.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Femoral Fractures; Fracture Fixation, Intramedullary; Free Radical Scavengers; Lung; Male; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome | 2004 |
Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
Topics: Acetylcysteine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Blotting, Western; Cell Survival; Chelating Agents; Chlorides; Copper; Detergents; Disease Models, Animal; Ditiocarb; Fibroblasts; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Minocycline; Mutation; Oxidative Stress; Paraquat; Peroxynitrous Acid; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Solubility; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Zinc Compounds | 2004 |
Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519.
Topics: Acetylcysteine; Animals; Biomarkers; Brain Chemistry; Brain Ischemia; Chemotherapy, Adjuvant; Disease Models, Animal; E-Selectin; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Inflammation; Intercellular Adhesion Molecule-1; Male; Neuroprotective Agents; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2004 |
N-acetyl-cysteine promotes angiostatin production and vascular collapse in an orthotopic model of breast cancer.
Topics: Acetylcysteine; Angiostatins; Animals; Antioxidants; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Chickens; Disease Models, Animal; DNA, Complementary; Endothelial Cells; Free Radical Scavengers; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Luminescent Proteins; Lymphatic Metastasis; Mammary Neoplasms, Animal; Mice; Mice, Nude; Microcirculation; Microscopy, Fluorescence; Models, Biological; Necrosis; Neoplasm Metastasis; Neoplasm Transplantation; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Vascular Endothelial Growth Factor A | 2004 |
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
Topics: Acetylcysteine; Animals; Brain Ischemia; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Ectodysplasins; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Attack, Transient; Male; Membrane Proteins; Neurologic Examination; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Time Factors | 2004 |
A low molecular weight copper chelator crosses the blood-brain barrier and attenuates experimental autoimmune encephalomyelitis.
Topics: Acetylcysteine; Administration, Oral; Animals; Antimetabolites, Antineoplastic; Biological Transport; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Chelating Agents; Copper; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Erythrocytes; Female; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinases; Molecular Weight; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Sulfhydryl Compounds; Treatment Outcome | 2004 |
Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Blotting, Western; Brain; Cell Count; Cell Death; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; MPTP Poisoning; PC12 Cells; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Time Factors; Tyrosine 3-Monooxygenase | 2004 |
Effects of N-acetylcysteine in hepatic ischemia-reperfusion injury during hemorrhagic shock.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Rats; Rats, Wistar; Reperfusion Injury; Shock, Hemorrhagic | 2004 |
The Leishmania chagasi proteasome: role in promastigotes growth and amastigotes survival within murine macrophages.
Topics: Acetylcysteine; Animals; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Leishmania; Leishmaniasis, Visceral; Leucine; Macrophages, Peritoneal; Male; Mice; Multienzyme Complexes; Oligopeptides; Phenylmethylsulfonyl Fluoride; Proteasome Endopeptidase Complex | 2004 |
[Influence of N-acetylcysteine on the cytokines and matrix metalloproteinases in chronic obstructive pulmonary disease rat models].
Topics: Acetylcysteine; Animals; Disease Models, Animal; Interferon-gamma; Interleukin-4; Male; Matrix Metalloproteinase 12; Matrix Metalloproteinase 9; Metalloendopeptidases; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-1; Tobacco Smoke Pollution | 2004 |
Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation.
Topics: Acetylcysteine; Adenosine; Allopurinol; Aminoimidazole Carboxamide; Animals; Apoptosis; Creatinine; Disease Models, Animal; Dogs; Glutathione; Graft Survival; Immunohistochemistry; Insulin; Kidney; Kidney Transplantation; Male; Nephrectomy; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Preservation; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Ribonucleotides; Transplantation, Autologous; Tumor Necrosis Factor-alpha | 2004 |
N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Acetylcysteine; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Antigens; CD11b Antigen; Cell Count; Cell Death; Cytokines; Demyelinating Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Infant, Newborn; Leukomalacia, Periventricular; Lipopolysaccharides; Male; Myelin Basic Protein; Nerve Degeneration; Neuroprotective Agents; O Antigens; Oligodendroglia; Pregnancy; Proteoglycans; Rats; Rats, Sprague-Dawley; Receptor, Platelet-Derived Growth Factor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Survival Rate; Time Factors; Transcription Factors | 2004 |
[Protective effect of N-acetylcysteine on acute lung injury caused by exposure to rocket liquid propellant].
Topics: Acetylcysteine; Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Dimethylhydrazines; Disease Models, Animal; Glutathione Peroxidase; Lipid Peroxidation; Lung; Male; Malondialdehyde; Nitrogen Oxides; Random Allocation; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2004 |
The effect of inducible nitric oxide synthase on postoperative adhesion formation in rats.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Fibrosis; Inflammation; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peritoneal Diseases; Peritoneum; Postoperative Complications; Rats; Rats, Wistar; Tissue Adhesions | 2004 |
N-acetyl-cysteine accelerates transfer of diabetes into non-obese diabetic scid mice.
Topics: Acetylcysteine; Animals; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Islets of Langerhans; Lymphocyte Transfusion; Mice; Mice, Inbred NOD; Mice, SCID; Polymerase Chain Reaction; Spleen; Time Factors | 2004 |
Effects of N-acetylcysteine on oxidant-antioxidant balance in oleic acid-induced lung injury.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Drug Administration Schedule; Female; Injections, Intravenous; Lung; Malondialdehyde; Oleic Acid; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Respiratory Distress Syndrome; Sodium-Potassium-Exchanging ATPase; Time Factors | 2004 |
N-Acetylcysteine ameliorates lithium-induced renal failure in rats.
Topics: Acetylcysteine; Animals; Biopsy, Needle; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Immunohistochemistry; Injections, Intraperitoneal; Kidney Function Tests; Lithium; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sensitivity and Specificity | 2005 |
Prevention of cisplatin ototoxicity using transtympanic N-acetylcysteine and lactate.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cisplatin; Cochlea; Disease Models, Animal; Guinea Pigs; Hair Cells, Auditory, Outer; Hearing Loss; Isotonic Solutions; Otoacoustic Emissions, Spontaneous; Random Allocation; Ringer's Lactate; Therapeutics | 2004 |
Effect of N-acetylcysteine on antioxidant status in glycerol-induced acute renal failure in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Analysis of Variance; Animals; Disease Models, Animal; Female; Glycerol; Kidney Function Tests; Male; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity | 2004 |
[The effect of antioxidant treatment in pneumonia of granulocytopenic rats].
Topics: Acetylcysteine; Agranulocytosis; Animals; Antioxidants; Disease Models, Animal; Male; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Sprague-Dawley | 2004 |
N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury.
Topics: Acetylcysteine; Animals; Blotting, Western; Brain Injuries; Disease Models, Animal; Enzyme Induction; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Immunohistochemistry; Male; Oxygenases; Percussion; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts; Time Factors | 2005 |
The effect of N-acetylcysteine on Clara cells and Clara cell 16 kDa protein in a murine model of allergen-induced airway inflammation.
Topics: Acetylcysteine; Administration, Oral; Animals; Blotting, Western; Bronchi; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Disease Models, Animal; Female; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Uteroglobin | 2005 |
Gene therapy for barrett's esophagus: adenoviral gene transfer in different intestinal models.
Topics: Acetylcysteine; Adenoviridae; Animals; Barrett Esophagus; Caco-2 Cells; DEAE-Dextran; Disease Models, Animal; Genetic Therapy; Green Fluorescent Proteins; Humans; Intestinal Mucosa; Rats; Transduction, Genetic | 2005 |
Nutritional regulation of proteases involved in fetal rat insulin secretion and islet cell proliferation.
Topics: Acetylcysteine; Animals; Calcium-Binding Proteins; Calpain; Cell Proliferation; Cells, Cultured; Diet, Protein-Restricted; Disease Models, Animal; Female; Fetal Nutrition Disorders; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Glycoproteins; Insulin; Insulin Secretion; Islets of Langerhans; Maternal-Fetal Exchange; Peptide Hydrolases; Pregnancy; Proteasome Endopeptidase Complex; Protein Array Analysis; Rats; Rats, Wistar; Taurine | 2005 |
Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: erdosteine and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; Bleomycin; Disease Models, Animal; Drug Interactions; Male; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Thioglycolates; Thiophenes | 2005 |
Prevention of impulse noise-induced hearing loss with antioxidants.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Antioxidants; Chinchilla; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Recovery of Function | 2005 |
Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration.
Topics: Acetylcysteine; Animals; Apolipoproteins E; Cell Line, Tumor; Dietary Supplements; Disease Models, Animal; Folic Acid Deficiency; Glutathione; Glutathione Synthase; Maze Learning; Mice; Mice, Knockout; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Tubercidin; Vitamin E Deficiency | 2004 |
Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis.
Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Antioxidants; Arginine; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Therapy, Combination; Injections, Intravenous; Lung; Male; Pancreas; Pancreatitis; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Time Factors | 2005 |
The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats.
Topics: Acetylcysteine; Animals; Blood Pressure; Disease Models, Animal; Female; Fetal Weight; Hypertension; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Uterus | 2005 |
Magnesium supplementation combined with N-acetylcysteine protects against postischemic acute renal failure.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Cell Membrane; Dietary Supplements; Disease Models, Animal; Glomerular Filtration Rate; Ischemia; Kidney; Magnesium Chloride; Male; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Renal Circulation | 2005 |
Role of oxidative stress in pathophysiology of peripheral neuropathy and modulation by N-acetyl-L-cysteine in rats.
Topics: Acetylcysteine; Animals; Behavior, Animal; Biomarkers; Disease Models, Animal; Free Radical Scavengers; Glutathione; Ligation; Male; Malondialdehyde; Neuralgia; Oxidative Stress; Pain Measurement; Peripheral Nervous System Diseases; Rats; Rats, Wistar; Reactive Oxygen Species; Sciatic Neuropathy; Superoxide Dismutase; Treatment Outcome | 2006 |
The effect of N-acetylcysteine on pulmonary lipid peroxidation and tissue damage.
Topics: Acetylcysteine; Animals; Antioxidants; Common Bile Duct; Disease Models, Animal; Injections, Intraperitoneal; Jaundice, Obstructive; Ligation; Lipid Peroxidation; Lipopolysaccharides; Lung; Male; Malondialdehyde; Peroxidase; Rats; Rats, Wistar | 2005 |
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Silencing; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Streptozocin; Trans-Activators; Transcription Factors; Transfection | 2005 |
Angiotensin II-dependent vascular alterations in young cardiomyopathic hamsters: role for oxidative stress.
Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Blood Pressure; Cardiomyopathies; Cricetinae; Disease Models, Animal; Losartan; Male; Mesocricetus; NADPH Oxidases; Oxidative Stress; Superoxides | 2006 |
N-acetylcysteine increases manganese superoxide dismutase activity in septic rat diaphragms.
Topics: Acetylcysteine; Analysis of Variance; Animals; Biopsy, Needle; Diaphragm; Disease Models, Animal; Immunohistochemistry; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Sepsis; Superoxide Dismutase | 2005 |
Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment.
Topics: Acetylcysteine; Alzheimer Disease; Analysis of Variance; Animals; Antioxidants; Astrocytes; Cerebral Cortex; Chelating Agents; Disease Models, Animal; Drug Interactions; Edetic Acid; Male; Manganese; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
N-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion.
Topics: Acetylcysteine; Acute Kidney Injury; Analysis of Variance; Animals; Biopsy, Needle; Creatinine; Disease Models, Animal; Glomerular Filtration Rate; Glutathione; Immunohistochemistry; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Reperfusion Injury; Statistics, Nonparametric | 2006 |
Effects of N-acetylcysteine plus deferoxamine in lipopolysaccharide-induced acute lung injury in the rat.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Interleukin-1; Lipopolysaccharides; Male; Oxidative Stress; Rats; Rats, Wistar; Respiratory Distress Syndrome; Siderophores; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2006 |
More antioxidants in sepsis: still paved with uncertainties.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Humans; Oxidation-Reduction; Oxidative Stress; Respiratory Distress Syndrome; Sepsis; Siderophores | 2006 |
Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine.
Topics: Acetylcysteine; Adaptor Proteins, Vesicular Transport; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamic Acid; Hippocampus; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; SNARE Proteins; Synaptic Membranes; Synaptic Transmission; Time Factors; Up-Regulation | 2006 |
Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegeneration.
Topics: Acetylcysteine; Adenosine Triphosphate; Animal Feed; Animals; Ascorbic Acid; Carnitine; Cloning, Molecular; Creatine; Diet; Disease Models, Animal; Drosophila; Drosophila melanogaster; Edetic Acid; Ginkgo biloba; Heterozygote; Humans; Inosine; Iron; Mutation; Neurodegenerative Diseases; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Transgenes; Vitamin E | 2005 |
Effects of N-acetylcysteine on radiocontrast nephropathy in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney Function Tests; Kidney Tubules; Probability; Radiopharmaceuticals; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Factors; Sensitivity and Specificity | 2006 |
The antioxidant effect of N-acethylcysteine on experimental contusion in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Edema; Brain Injuries; Disease Models, Animal; Injections, Intraperitoneal; Intracranial Pressure; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2005 |
Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver.
Topics: Acetylcysteine; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Citric Acid Cycle; Cytoprotection; Disease Models, Animal; Glutathione; Liver; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mitochondria, Liver; Nitro Compounds; Oxidative Stress; Propionates; Pyruvate Carboxylase; Pyruvate Dehydrogenase Complex; Taurine; tert-Butylhydroperoxide | 2006 |
N-acetylcysteine antagonizes the development but does not reverse ACTH-induced hypertension in the rat.
Topics: Acetylcysteine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Disease Models, Animal; Free Radical Scavengers; Hypertension; Male; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2006 |
Oral administration of S-nitroso-N-acetylcysteine prevents the onset of non alcoholic fatty liver disease in rats.
Topics: Acetylcysteine; Administration, Oral; Animals; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Liver; Male; Necrosis; Nitrates; Rats; Rats, Wistar; Transaminases | 2006 |
Antioxidant therapy with N-acetylcysteine plus mesalamine accelerates mucosal healing in a rodent model of colitis.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biopsy, Needle; Colitis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Immunohistochemistry; Inflammation Mediators; Male; Mesalamine; Peroxidase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sensitivity and Specificity | 2006 |
Modulation of pentylenetetrazole-induced seizures and oxidative stress parameters by sodium valproate in the absence and presence of N-acetylcysteine.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Anticonvulsants; Antioxidants; Aspartate Aminotransferases; Brain; Disease Models, Animal; Drug Therapy, Combination; Glutathione; Kidney; Liver; Mice; Oxidative Stress; Pentylenetetrazole; Seizures; Thiobarbituric Acid Reactive Substances; Valproic Acid | 2006 |
Azathioprine hepatotoxicity and the protective effect of liquorice and glycyrrhizic acid.
Topics: Acetylcysteine; Animals; Azathioprine; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Glycyrrhiza; Glycyrrhizic Acid; Hepatocytes; Humans; Immunosuppressive Agents; Male; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Species Specificity | 2006 |
Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway.
Topics: Acetylcysteine; Alkaloids; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzylisoquinolines; Caspase 3; Caspases; Cysteine; Cytochromes c; Disease Models, Animal; Glutathione; Inflammation Mediators; Macrophages, Alveolar; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oxidative Stress; Paclitaxel; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Silicon Dioxide; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha | 2006 |
Impairment in consolidation of learned place preference following dopaminergic neurotoxicity in mice is ameliorated by N-acetylcysteine but not D1 and D2 dopamine receptor agonists.
Topics: Acetylcysteine; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Conditioning, Operant; Disease Models, Animal; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Free Radical Scavengers; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutathione; Learning Disabilities; Male; Methamphetamine; Mice; Neurotoxicity Syndromes; Tyrosine 3-Monooxygenase | 2007 |
Oxidative stress in a rat model of chronic gliosis.
Topics: Acetylcysteine; Aldehydes; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cells, Cultured; Chronic Disease; Disease Models, Animal; Embryo, Mammalian; Fetal Tissue Transplantation; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Gliosis; Ibuprofen; Lipid Peroxidation; Oxidative Stress; Protein Carbonylation; Rats; Time Factors | 2007 |
Effect of N-acetylcysteine, allopurinol and vitamin E on jaundice-induced brain oxidative stress in rats.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Brain; Cysteine; Disease Models, Animal; Jaundice, Obstructive; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Rats; Sulfhydryl Compounds; Treatment Outcome; Vitamin E | 2006 |
Effects of N-acetylcysteine on the lung histopathology and oxidant-antioxidant status in rabbits exposed to cigarette smoke.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Expectorants; Injections, Intraperitoneal; Lung; Lung Diseases, Obstructive; Male; Rabbits; Smoking | 2006 |
Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach.
Topics: Acetylcysteine; Animals; Aprotinin; Biomarkers; Calcium Dobesilate; Creatine Kinase; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Hemostatics; L-Lactate Dehydrogenase; Lower Extremity; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Thiobarbituric Acid Reactive Substances; Treatment Outcome | 2006 |
Protective effects of N-acetylcysteine and erdosteine on hemorrhagic shock-induced acute lung injury.
Topics: Acetylcysteine; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Free Radical Scavengers; Glutathione; Lung; Macrophages, Alveolar; Male; Malondialdehyde; Neutrophils; Premedication; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome; Shock, Hemorrhagic; Thioglycolates; Thiophenes | 2006 |
N-acetylcysteine treatment protects against VEGF-receptor blockade-related emphysema.
Topics: Acetylcysteine; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Emphysema; Heme Oxygenase-1; Hypertrophy, Right Ventricular; Indoles; Lung; Male; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor | 2004 |
N-acetyl-cysteine protects liver from apoptotic death in an animal model of fulminant hepatic failure.
Topics: Acetylcysteine; Animals; Animals, Inbred Strains; Antioxidants; Apoptosis; Caliciviridae Infections; Disease Models, Animal; Hemorrhagic Disease Virus, Rabbit; Hepatocytes; Liver; Liver Failure, Acute; Oxidative Stress; Rabbits | 2006 |
Antioxidant N-acetylcysteine inhibits the activation of JNK3 mediated by the GluR6-PSD95-MLK3 signaling module during cerebral ischemia in rat hippocampus.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Brain Ischemia; Disease Models, Animal; Disks Large Homolog 4 Protein; Enzyme Activation; Gene Expression Regulation; GluK2 Kainate Receptor; Hippocampus; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Kinase Kinase 11; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Signal Transduction; Time Factors | 2006 |
N-Acetylcysteine improves renal dysfunction, ameliorates kidney damage and decreases blood pressure in salt-sensitive hypertension.
Topics: Acetylcysteine; Animals; Blood Pressure; Disease Models, Animal; Free Radical Scavengers; Glomerular Filtration Rate; Glutathione; Hypertension; Kidney Diseases; Male; Oxidative Stress; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary | 2006 |
Free radical scavengers are more effective than indomethacin in the prevention of experimentally induced heterotopic ossification.
Topics: Acetylcysteine; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Double-Blind Method; Drug Synergism; Female; Free Radical Scavengers; Hindlimb; Indomethacin; Ossification, Heterotopic; Osteogenesis; Rabbits; Radiography; Random Allocation | 2007 |
Beneficial effect of N-acetyl-cysteine on renal injury triggered by ischemia and reperfusion.
Topics: Acetylcysteine; Animals; Dendritic Cells; Disease Models, Animal; Kidney Function Tests; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Renal Circulation; Reperfusion Injury; T-Lymphocytes; Transplantation, Isogeneic | 2006 |
Perturbed synaptosomal calcium homeostasis and behavioral deficits following carbofuran exposure: neuroprotection by N-acetylcysteine.
Topics: Acetylcysteine; Animals; Calcium; Calcium-Transporting ATPases; Carbofuran; Cholinesterase Inhibitors; Disease Models, Animal; Homeostasis; Lipid Peroxidation; Male; Neuroprotective Agents; Potassium; Rats; Rats, Wistar; Synaptosomes | 2007 |
Protective effects of Gingko biloba on thioacetamide-induced fulminant hepatic failure in rats.
Topics: Acetylcysteine; Alanine Transaminase; Ammonia; Animals; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drugs, Chinese Herbal; Free Radical Scavengers; Ginkgo biloba; Hepatic Encephalopathy; Liver; Male; Necrosis; Oxidative Stress; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Severity of Illness Index; Thioacetamide; Thiobarbituric Acid Reactive Substances | 2006 |
N-acetylcysteine to ameliorate acute renal injury in a rat cardiopulmonary bypass model.
Topics: Acetylcysteine; Acute Kidney Injury; Analysis of Variance; Animals; Cardiopulmonary Bypass; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation Mediators; Kidney Function Tests; Male; Oxidative Stress; Postoperative Complications; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Sensitivity and Specificity | 2007 |
Which comes first: renal inflammation or oxidative stress in spontaneously hypertensive rats?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Age Factors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; Disease Models, Animal; Disease Progression; DNA Damage; Glutathione; Hypertension; Kidney Cortex; Male; NADPH Oxidases; Nephritis; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Tyrosine | 2007 |
Specific activation of the different fibrogenic cells in rat cultured liver slices mimicking in vivo situations.
Topics: Acetaminophen; Acetylcysteine; Animal Use Alternatives; Animals; Antioxidants; Bile Ducts, Intrahepatic; Cell Survival; Disease Models, Animal; Drug Antagonism; Epidermal Growth Factor; Estradiol; Fibroblasts; Hepatocytes; Kupffer Cells; Liver; Liver Cirrhosis; Male; Necrosis; Organ Culture Techniques; Portal System; Rats; Rats, Wistar; Thioacetamide | 2007 |
The effects of N-acetylcysteine on bile duct ligation-induced liver fibrosis in rats.
Topics: Acetylcysteine; Animals; Bile Ducts; Collagen; Disease Models, Animal; Free Radical Scavengers; Glutathione; Ligation; Liver Cirrhosis; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Spectrophotometry | 2007 |
Protective effects of caffeic acid phenethyl ester, vitamin C, vitamin E and N-acetylcysteine on vancomycin-induced nephrotoxicity in rats.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Caffeic Acids; Catalase; Disease Models, Animal; Drinking; Drug Combinations; Injections, Intramuscular; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Phenylethyl Alcohol; Rats; Rats, Wistar; Vancomycin; Vitamin E; Water Supply | 2007 |
Effects of N-acetylcysteine on oxidative stress in rats with non-alcoholic steatohepatitis.
Topics: Acetylcysteine; Animals; Dietary Fats; Disease Models, Animal; Fatty Liver; Free Radical Scavengers; Hepatitis; Liver; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2007 |
Oxidative stress and metabolism in animal model of colitis induced by dextran sulfate sodium.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Colitis, Ulcerative; Colon; Deferoxamine; Dextran Sulfate; Disease Models, Animal; Electron Transport Complex II; Electron Transport Complex IV; Gastrointestinal Agents; Leukocyte Count; Lipid Peroxidation; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Succinate Dehydrogenase; Thiobarbituric Acid Reactive Substances | 2007 |
ICAM-1 and CD11b/CD18 expression during acute pancreatitis induced by bile-pancreatic duct obstruction: effect of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; CD11b Antigen; CD18 Antigens; Cholestasis; Disease Models, Animal; Intercellular Adhesion Molecule-1; Male; Monocytes; Neutrophils; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Wistar; RNA, Messenger; Up-Regulation | 2007 |
Comparative treatment of alpha-amanitin poisoning with N-acetylcysteine, benzylpenicillin, cimetidine, thioctic acid, and silybin in a murine model.
Topics: Acetylcysteine; Alanine Transaminase; Amanitins; Animals; Antidotes; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cimetidine; Disease Models, Animal; Male; Mice; Mushroom Poisoning; Penicillin G; Random Allocation; Silybin; Silymarin; Thioctic Acid | 2007 |
The role of reactive oxygen species in the hearts of dystrophin-deficient mdx mice.
Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Calcium; Disease Models, Animal; Dystrophin; Fibrosis; Free Radical Scavengers; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscular Dystrophy, Duchenne; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species | 2007 |
Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; NF-kappa B; Proteasome Inhibitors | 2007 |
Do N-acetylcystein, beta-glucan, and coenzyme Q10 mollify myocardial ischemia-reperfusion injury?
Topics: Acetylcysteine; Animals; Antioxidants; beta-Glucans; Coenzymes; Disease Models, Animal; Female; Myocardial Reperfusion Injury; Rabbits; Ubiquinone | 2007 |
Reversal of hyperoxaluria-induced alteration in rat liver by administration of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Catalase; Disease Models, Animal; Free Radical Scavengers; Hyperoxaluria; Lipid Metabolism; Lipid Peroxidation; Liver; Liver Diseases; Male; Membrane Fluidity; Oxalates; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2007 |
Effects of laxative and N-acetylcysteine on mucus accumulation, bacterial load, transit, and inflammation in the cystic fibrosis mouse small intestine.
Topics: Acetylcysteine; Animals; Bacteria; Body Weight; Cathartics; Cystic Fibrosis; Disease Models, Animal; Expectorants; Gastric Emptying; Gastrointestinal Transit; Gene Expression Regulation; Immunity, Innate; Inflammation; Intestine, Small; Mice; Mice, Inbred CFTR; Mucus; Polyethylene Glycols; RNA, Bacterial; RNA, Ribosomal, 16S | 2007 |
Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity.
Topics: Acetophenones; Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Caspase 3; Cryoultramicrotomy; Disease Models, Animal; Endothelial Cells; Injections, Intraperitoneal; Lipid Peroxides; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Neuroglia; Oxygen; Pericytes; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Retinal Neovascularization; Retinal Vessels; Vascular Endothelial Growth Factor A | 2007 |
Protective effects of melatonin and N-acetylcysteine on hepatic injury in a rat cardiopulmonary bypass model.
Topics: Acetylcysteine; Animals; Apoptosis; Cardiopulmonary Bypass; Disease Models, Animal; Free Radical Scavengers; Glutathione; Liver; Male; Malondialdehyde; Melatonin; Nitric Oxide Synthase; Oxidative Stress; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2007 |
[Protective effect of N-acetyl-L-cysteine on liver and lung injury in mice after partial hepatic ischemia/reperfusion].
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Disease Models, Animal; Liver; Lung; Lung Injury; Mice; Mice, Inbred BALB C; Random Allocation; Reperfusion Injury; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2007 |
N-acetyl cysteine attenuates the inflammatory response in warm ischemic pig lungs.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Inflammation; Ischemia; Lung; Lung Transplantation; Organ Preservation; Reperfusion Injury; Swine; Temperature | 2008 |
The oxidative status of blood cells in a murine model of graft-versus-host disease.
Topics: Acetylcysteine; Animals; Blood Cells; Cells, Cultured; Disease Models, Animal; Female; Flow Cytometry; Free Radical Scavengers; Graft vs Host Disease; Humans; Hypnotics and Sedatives; Male; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Propofol; Reactive Oxygen Species; Spleen; Tocopherols; Transplantation, Homologous; Transplantation, Isogeneic; Vitamin E; Whole-Body Irradiation | 2007 |
Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis.
Topics: Acetylcysteine; Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Collagenases; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Injections, Subcutaneous; Interleukin-1; Matrix Metalloproteinase 3; Pyrones; Random Allocation; Rats; Vanadates | 2007 |
Neutral sphingomyelinase inhibition participates to the benefits of N-acetylcysteine treatment in post-myocardial infarction failing heart rats.
Topics: Acetylcysteine; Animals; Cardiotonic Agents; Case-Control Studies; Disease Models, Animal; Echocardiography, Doppler; Glutathione; Heart Failure; Male; Myocardial Infarction; Oxidative Stress; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sphingomyelin Phosphodiesterase; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cues; Disease Models, Animal; Drug Interactions; Extinction, Psychological; Free Radical Scavengers; Heroin; Heroin Dependence; Male; Narcotics; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine.
Topics: Acetylcysteine; Aged; Aged, 80 and over; Amino Acids; Analysis of Variance; Animals; Behavior, Animal; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Fluid; Female; Free Radical Scavengers; Glutamic Acid; Glycine; Humans; Interpersonal Relations; Male; Maze Learning; Microdialysis; Phencyclidine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia; Xanthenes | 2008 |
Antioxidant treatment prevented late memory impairment in an animal model of sepsis.
Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Cecum; Deferoxamine; Disease Models, Animal; Habituation, Psychophysiologic; Intestinal Perforation; Ligation; Male; Memory Disorders; Rats; Rats, Wistar; Sepsis | 2007 |
Proteasome inhibitor lactacystin ablates liver injury induced by intestinal ischaemia-reperfusion.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Feasibility Studies; Intercellular Adhesion Molecule-1; Intestines; L-Lactate Dehydrogenase; Liver; Liver Diseases; Male; Neutrophil Infiltration; Peroxidase; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Reperfusion Injury; Transcription Factor RelA | 2007 |
Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site.
Topics: Acetylcysteine; Administration, Topical; Animals; Animals, Outbred Strains; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis; Dexamethasone; Disease Models, Animal; Ear, External; Edema; Enzyme Inhibitors; Indomethacin; Male; Mice; Mice, Inbred ICR; Neutrophils; Peroxidase | 2008 |
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Capillary Permeability; Cytokines; Disease Models, Animal; Free Radical Scavengers; Inflammation; Male; Mice; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Respiratory Distress Syndrome; Ventilators, Mechanical | 2007 |
Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake.
Topics: Acetylcysteine; Adiponectin; Administration, Oral; Animals; Animals, Newborn; Antioxidants; Blood Glucose; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids; Glucose; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Ligation; Lipids; Male; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Pravastatin; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Recombinant Proteins; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Effect of N-acetylcysteine on carboplatin-induced ototoxicity and nitric oxide levels in a rat model.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Biomarkers; Carboplatin; Cochlea; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Follow-Up Studies; Free Radical Scavengers; Glutathione Peroxidase; Hearing Loss, Sensorineural; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spectrophotometry; Treatment Outcome | 2007 |
Salutary effects of N-acetylcysteine on apoptotic damage in a rat model of testicular torsion.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Catalase; Disease Models, Animal; Drug Administration Schedule; Glutathione Peroxidase; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spermatic Cord Torsion; Spermatozoa; Superoxide Dismutase; Testis | 2007 |
N-acetylcysteine attenuates lipopolysaccharide-induced apoptotic liver damage in D-galactosamine-sensitized mice.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Galactosamine; Lipopolysaccharides; Mice; Mice, Inbred Strains; Nitric Oxide; Tumor Necrosis Factor-alpha | 2007 |
Oxidative stress attenuates NO-induced modulation of sympathetic neurotransmission in the mesenteric arterial bed of spontaneously hypertensive rats.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Blood Pressure; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Splanchnic Circulation; Superoxides; Sympathetic Nervous System | 2008 |
Prophylactic effect of liposomal N-acetylcysteine against LPS-induced liver injuries.
Topics: Acetylcysteine; Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chloramines; Disease Models, Animal; Lipid Peroxidation; Lipopolysaccharides; Liver; Lysine; Male; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha | 2007 |
Activation of p38 MAPK by reactive oxygen species is essential in a rat model of stress-induced gastric mucosal injury.
Topics: Acetylcysteine; Animals; Apoptosis; Cold Temperature; Cyclic N-Oxides; Cytokines; Disease Models, Animal; Enzyme Activation; Epithelial Cells; Gastric Mucosa; Gene Expression Regulation; Imidazoles; Male; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Spin Labels; Stress, Psychological; Structure-Activity Relationship; Time Factors; Transcription Factor AP-1 | 2007 |
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Animal; Free Radical Scavengers; Glyburide; Heart Rate; Hydroxy Acids; Hypoxia; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Respiration, Artificial; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2008 |
Antidiabetic zinc(II)-N-acetyl-L-cysteine complex: evaluations of in vitro insulinomimetic and in vivo blood glucose-lowering activities.
Topics: Acetylcysteine; Adipocytes; Animals; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Evaluation, Preclinical; Glucose Tolerance Test; Hemoglobins; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Oxidative Stress; Rats; Rats, Wistar; Zinc | 2007 |
Prenatal diet determines susceptibility to cardiac ischaemia-reperfusion injury following treatment with diethylmaleic acid and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Diet, Protein-Restricted; Disease Models, Animal; Female; Glutathione; Heart; Hemodynamics; Maleates; Maternal Exposure; Myocardial Reperfusion Injury; Myocardium; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Ventricular Dysfunction, Left | 2008 |
Influence of N-acetylcysteine on renal toxicity of cadmium in rats.
Topics: Acetylcysteine; Animals; Cadmium Chloride; Catalase; Chemoprevention; Creatine; Disease Models, Animal; Drug Antagonism; Free Radical Scavengers; Glomerular Filtration Rate; Glutathione; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Urea | 2008 |
Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction.
Topics: 1-Methyl-4-phenylpyridinium; Acetylcysteine; Animals; Aspartic Acid; Behavior, Animal; Cysteine; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Transporter 1; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxamic Acids; In Vitro Techniques; Indazoles; Male; Mice; Mice, Inbred C57BL; Movement Disorders; MPTP Poisoning; Neuroprotective Agents; Oxidative Stress; Substantia Nigra | 2008 |
N-acetyl cysteine pre-treatment attenuates inflammatory changes in the warm ischemic murine lung.
Topics: Acetylcysteine; Animals; Biopsy; Bronchoalveolar Lavage; Cell Count; Chemokines; Cytokines; Disease Models, Animal; Female; Free Radical Scavengers; Intercellular Signaling Peptides and Proteins; Leukocytes; Lung; Lung Transplantation; Lymphocytes; Macrophages; Mice; Reperfusion Injury; Warm Ischemia | 2007 |
Inhibition of murine AIDS by pro-glutathione (GSH) molecules.
Topics: Acetylcysteine; Animals; Anti-HIV Agents; Cell Proliferation; Cysteamine; Disease Models, Animal; DNA, Viral; Female; Glutathione; Hypergammaglobulinemia; Immunoglobulin G; Leukemia Virus, Murine; Lymph Nodes; Lymphocytes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Organ Size; Polymerase Chain Reaction; Prodrugs; Spleen | 2008 |
Oral N-acetylcysteine reverses hyperoxia-related cough suppression in guinea pigs.
Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Citric Acid; Cough; Disease Models, Animal; Guinea Pigs; Hyperoxia; Lung; Lung Diseases; Male; Oxidative Stress; Physical Stimulation; Reflex | 2007 |
N-acetylcysteine as the magic bullet: too good to be true.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Embolism, Fat; Expectorants; Humans; Pulmonary Embolism; Respiratory Distress Syndrome | 2008 |
Oxidative modification of peroxiredoxin is associated with drug-induced apoptotic signaling in experimental models of Parkinson disease.
Topics: Acetylcysteine; Adrenergic Agents; Animals; Apoptosis; Caspase 3; Cell Line; Disease Models, Animal; Enzyme Activation; Mesencephalon; Neurons; Oxidation-Reduction; Oxidopamine; p38 Mitogen-Activated Protein Kinases; Parkinson Disease, Secondary; Peroxiredoxins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2008 |
N-Acetylcysteine ameliorates skeletal muscle pathophysiology in mdx mice.
Topics: Acetylcysteine; Animals; Caveolin 3; Disease Models, Animal; Dystroglycans; Dystrophin; Free Radical Scavengers; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Mutation; NF-kappa B; Reactive Oxygen Species | 2008 |
N-Acetylcysteine prevents ifosfamide-induced nephrotoxicity in rats.
Topics: Acetylcysteine; Animals; Antineoplastic Agents, Alkylating; beta 2-Microglobulin; Creatinine; Disease Models, Animal; Free Radical Scavengers; Glutathione; Glutathione Transferase; Ifosfamide; Kidney Diseases; Lipid Peroxides; Magnesium; Male; Rats; Rats, Wistar; Severity of Illness Index | 2008 |
Proteasome inhibitors in myocardial ischemia, some concerns.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Humans; Ischemic Preconditioning, Myocardial; Mice; Myocardial Ischemia; NF-kappa B; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reperfusion Injury; Risk Factors; Sensitivity and Specificity | 2008 |
Tissue damage in rat ovaries subjected to torsion and detorsion: effects of L-carnitine and N-acetyl cysteine.
Topics: Acetylcysteine; Animals; Carnitine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Free Radical Scavengers; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Interleukin-6; Malondialdehyde; Ovarian Diseases; Ovary; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Severity of Illness Index; Torsion Abnormality; Torsion, Mechanical; Vitamin B Complex | 2008 |
Between channels and tears: aim at ROS to save the membrane of dystrophic fibres.
Topics: Acetylcysteine; Animals; Caveolin 3; Disease Models, Animal; Dystroglycans; Dystrophin; Free Radical Scavengers; Mice; Mice, Inbred mdx; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Mutation; Reactive Oxygen Species | 2008 |
The molecular mechanisms of the attenuation of cisplatin-induced acute renal failure by N-acetylcysteine in rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Cross-Linking Reagents; Disease Models, Animal; Free Radical Scavengers; Male; Melatonin; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proline; Rats; Rats, Sprague-Dawley; Thiocarbamates; Tumor Necrosis Factor-alpha | 2008 |
Comparison of the protective effect of N-acetylcysteine by different treatments on rat myocardial ischemia-reperfusion injury.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Glutathione; Glutathione Peroxidase; I-kappa B Proteins; Infusions, Intravenous; Injections, Intravenous; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Phosphorylation; Rats; Rats, Wistar | 2008 |
Oxidant stress mediates inflammation and apoptosis in ventilator-induced lung injury.
Topics: Acetylcysteine; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Disease Models, Animal; Epithelial Cells; Free Radical Scavengers; Glutathione; Interleukin-6; Lung; Oxidative Stress; Pneumonia; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha; Ventilators, Mechanical | 2008 |
Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems.
Topics: Acetylcholine; Acetylcysteine; Aged; Aged, 80 and over; alpha-Synuclein; Animals; Basal Nucleus of Meynert; Cell Death; Cells, Cultured; Cerebral Cortex; Cholinergic Fibers; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Lewy Bodies; Lewy Body Disease; Male; Nerve Degeneration; Nerve Tissue Proteins; Neural Pathways; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Ubiquitin | 2008 |
Effects of postresuscitation N-acetylcysteine on cerebral free radical production and perfusion during reoxygenation of hypoxic newborn piglets.
Topics: Acetylcysteine; Animals; Animals, Newborn; Carotid Arteries; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Glutathione; Hydrogen Peroxide; Hypoxia-Ischemia, Brain; Lactates; Nitric Oxide; Oxidative Stress; Oxygen; Random Allocation; Regional Blood Flow; Swine; Tyrosine | 2008 |
Multiple molecular pathways are involved in the neuroprotection of GDNF against proteasome inhibitor induced dopamine neuron degeneration in vivo.
Topics: Acetylcysteine; Animals; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Nerve Degeneration; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Phosphatidylinositol 3-Kinases; Proteasome Inhibitors; Proto-Oncogene Proteins c-akt; Random Allocation; Signal Transduction; Substantia Nigra | 2008 |
Effects of N-acetylcysteine administration in hepatic microcirculation of rats with biliary cirrhosis.
Topics: Acetylcysteine; Animals; Antioxidants; Bile Ducts; Disease Models, Animal; Free Radical Scavengers; Ligation; Liver Circulation; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Microcirculation; Oxidants; Peptide Fragments; Procollagen; Rats; Rats, Sprague-Dawley; RNA, Messenger; Superoxide Dismutase; Thromboxane-A Synthase; Tyrosine; Vascular Resistance | 2008 |
Effects of N-acetylcysteine stereoisomers on oxygen-induced lung injury in rats.
Topics: Acetylcysteine; Administration, Oral; Animals; Cysteine; Disease Models, Animal; Glutathione; Hyperemia; Infusion Pumps, Implantable; Infusions, Intravenous; Lung; Male; Osmosis; Oxygen; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1995 |
Effects of N-acetylcysteine in endotoxic shock.
Topics: Acetylcysteine; Analysis of Variance; Animals; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Lactates; Random Allocation; Respiratory Function Tests; Shock, Septic; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1994 |
Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Interleukin-1; Lung; Male; Neutrophils; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiration; Respiratory Distress Syndrome | 1993 |
Role of tumour necrosis factor and reactive oxygen intermediates in lipopolysaccharide-induced pulmonary oedema and lethality.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Chlorpromazine; Dexamethasone; Disease Models, Animal; Endotoxins; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Neutrophils; Pulmonary Edema; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 1993 |
N-acetylcysteine ameliorates hyperoxic lung injury in the preterm guinea pig.
Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Catalase; Disease Models, Animal; Female; Glutathione; Glutathione Peroxidase; Guinea Pigs; Humans; Infant, Newborn; Infant, Premature, Diseases; Lung; Lung Diseases; Oxygen; Proteins; Ventilators, Mechanical | 1993 |
Contraction and relaxation of aortas from diabetic rats: effects of chronic anti-oxidant and aminoguanidine treatments.
Topics: Acetylcholine; Acetylcysteine; Analysis of Variance; Animals; Antioxidants; Aorta; Butylated Hydroxytoluene; Diabetes Mellitus, Experimental; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Guanidines; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley | 1996 |
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Base Sequence; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Dinoprost; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; F2-Isoprostanes; Gene Expression Regulation; Glutathione; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Lung; Lung Diseases; Male; Molecular Sequence Data; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Sepsis | 1996 |
Synergism between N-acetylcysteine and doxorubicin in the prevention of tumorigenicity and metastasis in murine models.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Survival Analysis | 1996 |
N-acetyl cysteine attenuates acute lung injury in the rat.
Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Capillary Permeability; CD11 Antigens; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Glutathione; Hemorrhage; Lipid Peroxidation; Lipopolysaccharides; Liver; Lung; Lung Diseases; Lung Injury; Male; Neutrophil Activation; Neutrophils; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1997 |
Assessment of anticollagenase treatments after insertion of a keratoprosthetic material in the rabbit cornea.
Topics: Acetylcysteine; Administration, Topical; Animals; Blotting, Western; Citrates; Collagenases; Cornea; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Gelatinases; Graft Survival; Implants, Experimental; Matrix Metalloproteinase Inhibitors; Medroxyprogesterone; Methacrylates; Ophthalmic Solutions; Prednisolone; Rabbits; Sodium Citrate; Tetracycline; Treatment Outcome | 1998 |
Participation of mercuric conjugates of cysteine, homocysteine, and N-acetylcysteine in mechanisms involved in the renal tubular uptake of inorganic mercury.
Topics: Acetylcysteine; Analysis of Variance; Animals; Biological Transport; Cysteine; Disease Models, Animal; Drug Interactions; Feces; Homocysteine; Kidney; Kidney Tubules, Proximal; Ligation; Liver; Male; Mercury; Normal Distribution; Rats; Rats, Sprague-Dawley; Reference Values; Ureter; Urine | 1998 |
Activation of polymorphonuclear leukocytes in oleic acid-induced lung injury.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Capillary Permeability; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Free Radical Scavengers; Guinea Pigs; Leukocyte Elastase; Male; Neutrophils; Oleic Acid; Prospective Studies; Pulmonary Circulation; Rats; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Superoxides | 1998 |
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan | 1999 |
Protective effect of N-acetylcysteine on multiple organ failure induced by zymosan in the rat.
Topics: Acetylcysteine; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Leukocyte Count; Male; Multiple Organ Failure; Nitrates; Nitric Oxide; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Analysis; Time Factors; Zymosan | 1999 |
Serum cytotoxin and oxidant stress markers in N-acetylcysteine treated thioacetamide hepatotoxicity of rats.
Topics: Acetylcysteine; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Cytotoxins; Disease Models, Animal; Free Radical Scavengers; Liver Diseases; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thioacetamide | 1999 |
N-Acetyl-cysteine inhibition of encephalomyelitis Theiler's virus-induced nitric oxide and tumour necrosis factor-alpha production by murine astrocyte cultures.
Topics: Acetylcysteine; Animals; Animals, Newborn; Astrocytes; Cardiovirus Infections; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Multiple Sclerosis; Nitric Oxide; Nitrites; Theilovirus; Tumor Necrosis Factor-alpha | 1999 |
Modulation of murine macrophage function by N-acetylcysteine in a model of endotoxic shock.
Topics: Acetylcysteine; Animals; Cell Adhesion; Chemotaxis; Disease Models, Animal; Escherichia coli; Female; In Vitro Techniques; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; N-Formylmethionine Leucyl-Phenylalanine; Phagocytosis; Shock, Septic; Superoxides; Tumor Necrosis Factor-alpha | 1999 |
Anti-oxidants as modulators of immune function.
Topics: Acetylcysteine; Adjuvants, Immunologic; Adult; Aged; Aging; Animals; Antioxidants; Cell Adhesion; Disease Models, Animal; Female; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Shock, Septic; Vitamin E | 2000 |
Effects of clinically used antioxidants in experimental pneumococcal meningitis.
Topics: Acetylcysteine; Animals; Antioxidants; Deferoxamine; Disease Models, Animal; Meningitis, Pneumococcal; Neurons; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2000 |
Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia.
Topics: Acetylcysteine; Animals; Cell Movement; Corpus Striatum; Cysteine Endopeptidases; Disease Models, Animal; Electroencephalography; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Macrophages; Male; Multienzyme Complexes; Neuroprotective Agents; Neutrophils; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Recovery of Function | 2000 |
N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis.
Topics: Acetylcysteine; Age Factors; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Mice; Mice, Transgenic; Motor Activity; Mutation; Superoxide Dismutase; Survival Rate | 2000 |
Human bladder cancer invasion model using rat bladder in vitro and its use to test mechanisms and therapeutic inhibitors of invasion.
Topics: Acetylcysteine; Administration, Intravesical; Animals; Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Differentiation; Cell Division; Disease Models, Animal; Drug Screening Assays, Antitumor; Epithelium; Humans; Neoplasm Invasiveness; Phenotype; Rats; Rats, Sprague-Dawley; Suramin; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Urokinase-Type Plasminogen Activator | 2001 |
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.
Topics: Acetylcysteine; Animals; Antioxidants; Chromans; Creatine Kinase; Disease Models, Animal; Gene Targeting; Heart; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Heterozygote; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Malondialdehyde; Membrane Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Reperfusion Injury; Thiourea | 2001 |
Protective effects of n-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat.
Topics: Acetylcysteine; Animals; Blotting, Western; Carrageenan; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Erythrocytes; Free Radical Scavengers; I-kappa B Proteins; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lung; Macrophages; Male; Malondialdehyde; Neutrophils; NF-KappaB Inhibitor alpha; Nitrates; Nitric Oxide; P-Selectin; Peroxidase; Pleurisy; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tyrosine | 2001 |
Kupffer cells and neutrophils as paracrine regulators of the heme oxygenase-1 gene in hepatocytes after hemorrhagic shock.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Pressure; Cells, Cultured; Chromans; Clodronic Acid; Deferoxamine; Disease Models, Animal; Gadolinium; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Kupffer Cells; Male; Neutrophils; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors; Vinblastine | 2001 |
N-acetyl-L-cysteine improves renal medullary hypoperfusion in acute renal failure.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Flow Velocity; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Glomerular Filtration Rate; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Regional Blood Flow; Reperfusion; Reperfusion Injury; Vena Cava, Inferior | 2001 |
Oxidative stress in brain during experimental bacterial meningitis: differential effects of alpha-phenyl-tert-butyl nitrone and N-acetylcysteine treatment.
Topics: Acetylcysteine; Animals; Brain; Cerebrospinal Fluid; Cyclic N-Oxides; Disease Models, Animal; Female; Free Radical Scavengers; Glutathione; Meningitis, Pneumococcal; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptococcus pneumoniae | 2001 |
N-acetylcysteine inhibited nuclear factor-kappaB expression and the intimal hyperplasia in rat carotid arterial injury.
Topics: Acetylcysteine; Animals; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Cell Division; Coronary Restenosis; Cytokines; Disease Models, Animal; Free Radical Scavengers; Hyperplasia; Immunohistochemistry; Inflammation; Male; Muscle, Smooth, Vascular; NF-kappa B; Rats; Rats, Sprague-Dawley; Tunica Intima | 2001 |
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cell Death; Cell Survival; Cells, Cultured; Corpus Striatum; Cysteine Endopeptidases; Disease Models, Animal; Gene Silencing; Genes, Dominant; Huntingtin Protein; Huntington Disease; Locomotion; Macromolecular Substances; Mice; Mice, Neurologic Mutants; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phenotype; Proteasome Endopeptidase Complex; Remission Induction; Tetracycline; Transgenes; Ubiquitin | 2001 |
Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia.
Topics: Acetylcysteine; Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain Ischemia; Cell Count; Cerebral Hemorrhage; Cerebral Infarction; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Intracranial Embolism; Male; Multienzyme Complexes; Neurologic Examination; Peroxidase; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Recombinant Proteins; Time Factors; Tissue Plasminogen Activator | 2001 |
Effectiveness of oral N -acetylcysteine in a rat experimental model of asthma.
Topics: Acetylcysteine; Animals; Antigens; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Eosinophils; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Free Radical Scavengers; Male; Rats; Rats, Inbred BN | 2002 |
Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model.
Topics: Acetylcysteine; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bacterial Toxins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; DNA; Enterotoxins; HLA-DR Antigens; Humans; Lectins, C-Type; Lymphocyte Activation; Mice; Mice, SCID; Multienzyme Complexes; NF-kappa B; Proteasome Endopeptidase Complex; Psoriasis; Receptors, Interleukin-2; Skin Transplantation; Superantigens; T-Lymphocytes; Transplantation, Heterologous | 2002 |
Reactive oxygen species contribute to contractile dysfunction following rapid ventricular pacing in dogs.
Topics: Acetylcysteine; Analysis of Variance; Animals; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Free Radical Scavengers; Heart Function Tests; Hemodynamics; Male; Myocardial Contraction; Myocardial Stunning; Probability; Random Allocation; Reactive Oxygen Species; Reference Values; Stroke Volume; Ventricular Dysfunction, Left | 2002 |
Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antioxidants; Cell Division; Colitis, Ulcerative; Colorectal Neoplasms; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL | 2002 |
N-acetylcysteine protects skin lesion induced by local extravasation of doxorubicin in a rat model.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Doxorubicin; Extravasation of Diagnostic and Therapeutic Materials; Male; Rats; Skin Diseases | 1992 |
Enhancement of ischaemic rabbit skin flap survival with the antioxidant and free-radical scavenger N-acetylcysteine.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Graft Survival; Ischemia; Malondialdehyde; Phenylhydrazines; Rabbits; Reperfusion Injury; Skin; Surgical Flaps; Thromboxane B2; Vascular Resistance | 1991 |
Protective effect of N-acetylcysteine on ischaemia-induced myocardial damage in canine heart.
Topics: Acetylcysteine; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Female; Glutathione; Male; Myocardial Infarction; Time Factors | 1991 |
Lathyrogenic agents as therapy for subglottic stenosis--a pilot study.
Topics: Acetylcysteine; Animals; Cicatrix; Collagen; Combined Modality Therapy; Disease Models, Animal; Dogs; Laryngostenosis; Laser Therapy; Penicillamine | 1987 |
Oral N-acetylcysteine speeds reversal of cigarette smoke-induced mucous cell hyperplasia in the rat.
Topics: Acetylcysteine; Administration, Oral; Albinism; Animals; Blood Cells; Disease Models, Animal; Health; Hyperplasia; Male; Nasal Mucosa; Rats; Rats, Inbred Strains; Smoking; Tuberculosis, Pulmonary | 1988 |
The effect of prostaglandins, branched-chain amino acids and other drugs on the outcome of experimental acute porcine hepatic failure.
Topics: Acetylcysteine; Amino Acids, Branched-Chain; Amino Acids, Essential; Animals; Carbon Tetrachloride; Cholestyramine Resin; Disease Models, Animal; Hepatic Encephalopathy; Phosphatidylcholines; Prostaglandins; Silymarin; Swine | 1987 |
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes | 1974 |
Mucomyst (acetylcysteine) in the treatment of corneal alkali burns.
Topics: Acetylcysteine; Alkalies; Animals; Burns, Chemical; Corneal Injuries; Disease Models, Animal; Eye Burns; Rabbits; Silver Proteins | 1972 |