acetylcysteine has been researched along with Disease Exacerbation in 92 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (5.43) | 18.2507 |
| 2000's | 21 (22.83) | 29.6817 |
| 2010's | 59 (64.13) | 24.3611 |
| 2020's | 7 (7.61) | 2.80 |
| Authors | Studies |
|---|---|
| Biswas, S; Roy, T; Sengupta, P | 1 |
| Agić, A; Buha, I; Dimic-Janjic, S; Ilić, A; Ilić, B; Milenković, B; Mirić, M; Nagorni-Obradović, L; Popević, S; Simić, M; Škodrić-Trifunović, V; Stjepanović, M | 1 |
| Graves, JS; Henry, RG; Mowry, EM; Nourbakhsh, B; Schoeps, VA; Stern, WA; Waubant, E; Zhang, L | 1 |
| Chen, H; Duan, Y; Fu, Y; Jiang, E; Jiang, Y; Li, W; Luo, C; Luo, T; Xue, G; Zhou, H; Zong, K | 1 |
| Harato, K; Ito, E; Kaneko, Y; Kobayashi, S; Kobayashi, T; Matsumoto, M; Miyamoto, K; Miyamoto, T; Nakamura, M; Nakamura, S; Niki, Y; Sato, Y; Soma, T; Tanigawa, N | 1 |
| Allen, MR; Avin, K; Chen, N; McNerney, E; Moe, S; Nyman, J; Wallace, J | 1 |
| Angelillo, IF; Barone, B; Boccellino, M; Boffo, S; Crocetto, F; Di Domenico, M; Di Zazzo, E; Galasso, G; Imbimbo, C; Quagliuolo, L; Sciarra, A; Settembre, G | 1 |
| Cao, MM; Li, YM; Sun, B; Xu, C; Yang, LY; Yu, L; Zhao, YR | 1 |
| Chien, WC; Chung, CH; Liao, CY; Lin, FH; Tsao, CH; Wang, CC; Wu, CC | 1 |
| Calzetta, L; Cazzola, M; Hanania, NA; Matera, MG; Rogliani, P | 1 |
| Berg, T; Borlak, J; van Bömmel, F | 1 |
| Chen, SP; Fuh, JL; Hsu, WC; Liu, TY; Tsou, HH; Wang, HT | 1 |
| Brooks, HL; Coombes, JS; Gobe, GC; Johnson, DW; Morais, C; Roy, SF; Sanchez, WY; Small, DM | 1 |
| Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Rinaldi, B; Rogliani, P | 1 |
| McClain, SA; Singer, AJ; Towery, H | 1 |
| Azuma, A; Bando, M; Date, H; Ebina, M; Fukuoka, J; Gemma, A; Goto, Y; Hasegawa, Y; Hattori, N; Homma, S; Inase, N; Inoue, Y; Ishii, Y; Izumi, S; Johkoh, T; Kido, T; Kishaba, T; Kishi, K; Miyamoto, A; Mukae, H; Nakayama, T; Nishioka, Y; Ogura, T; Sakamoto, S; Sasaki, S; Suda, T; Sugino, K; Taguchi, Y; Takahashi, H; Takahashi, K; Taniguchi, H; Watanabe, K; Yokoyama, A; Yoshino, I | 1 |
| Chu, Y; Liu, J; Liu, R; Qian, T; Wang, L; Wang, Z; Zhang, H | 1 |
| Calverley, PMA; Criner, GJ; Fabbri, LM; Papi, A; Zheng, J | 1 |
| Moore, R; Nicholas, WA | 1 |
| Chen, MJ; Ding, YX; Tong, ZQ; Yang, GL | 1 |
| Baker, B; Chatterjee, A; Cheng, PW; Ingersoll, MA; Kosmacek, EA; Lin, MF; Miller, DR; Oberley-Deegan, RE; Shrishrimal, S; Zhu, Y | 1 |
| Gasbarrini, A; Gibiino, G; Richeldi, L; Varone, F | 1 |
| Kalivas, P; Post, RM | 1 |
| Droin, N; Lacout, C; Le Couédic, JP; Marty, C; Plo, I; Ribrag, V; Solary, E; Vainchenker, W; Villeval, JL | 1 |
| Ancochea, J; Bollo, E; Fernández-Fabrellas, E; Franquet, T; Molina-Molina, M; Montero, MA; Serrano-Mollar, A; Xaubet, A | 1 |
| Hu, ZW; Hua, F; Lin, H; Liu, XB; Yu, JJ | 1 |
| Homma, S; Ishida, F; Isobe, K; Itoh, T; Muramatsu, Y; Sakamoto, S; Satoh, K; Sugino, K | 1 |
| Cai, W; Lei, S; Shen, Y; Zhang, Z | 1 |
| Cho, KH; Choi, MJ; Hwang, MH; Jeong, KJ; Kim, JJ; Lee, HY; Park, CG; Shin, SC | 1 |
| Bergo, MO; Ibrahim, MX; Larsson, E; Lindahl, P; Nilsson, JA; Sayin, VI | 1 |
| Choi, EJ; Hong, MP; Kie, JH; Kim, HR; Lee, A; Lee, HK; Lim, W; Moon, BI; Seoh, JY | 1 |
| Biasi, F; Gamba, P; Gargiulo, S; Giaccone, G; Guglielmotto, M; Iuliano, L; Leonarduzzi, G; Mauro, A; Monteleone, D; Poli, G; Tamagno, E; Testa, G; Zerbinati, C | 1 |
| Li, J; Xu, G; Yan, W | 1 |
| Braido, F; Corsico, A; Di Marco, F; Santus, P; Scichilone, N; Solidoro, P | 1 |
| Anstrom, KJ; de Andrade, JA; King, TE; Martinez, FJ; Raghu, G | 1 |
| Chen, W; Hua, S; Qu, J; Reinach, PS; Ren, Y; She, Y; Xiao, B; Zheng, Q | 1 |
| Eggermont, K; Feng, Y; Gao, M; Liu, G; Schouteden, S; Sorci-Thomas, MG; Van Veldhoven, PP; Verfaillie, CM; Zhao, D | 1 |
| Ehlers-Tenenbaum, S; Herth, FJ; Heussel, CP; Kahn, N; Kreuter, M; Oltmanns, U; Palmowski, K; Puderbach, M; Schnabel, PA; Träger, A; Warth, A; Wenz, H; Wiebel, M | 1 |
| Tse, HN; Tseng, CZ | 1 |
| Francis, PS; Frazier, AE; Gray, LJ; Hannan, AJ; McGee, SL; Renoir, T; Smith, ZM; Thorburn, DR; Wright, DJ | 1 |
| Dalton, ND; Divakaruni, AS; Dorn, GW; Gray, CB; Gu, Y; Heller Brown, J; Ling, H; Matkovich, SJ; Miyamoto, S; Murphy, AN; Peterson, KL; Westenbrink, BD; Zambon, AC | 1 |
| Einecke, D | 1 |
| Dai, LM; Fang, LZ; Feng, JG; Fu, WP; Liu, H; Liu, L; Shu, JK; Zhang, JQ; Zhao, ZH | 1 |
| Atkinson, SR; Bongiorno, CM; Chandar, AK; Loomba, R; Murad, MH; Shah, VH; Singal, AK; Singh, S; Thursz, MR | 1 |
| Brodsky, SV; Cianciolo, RE; Feinstein, DL; Hebert, L; Muni, N; Nadasdy, T; Rovin, BH; Rubinstein, I; Satoskar, AA; Ware, KM; Weinberg, G | 1 |
| Calzetta, L; Cazzola, M; Chuchalin, AG; Jardim, J; Matera, MG; Page, C; Rogliani, P | 1 |
| Bjørn, ME; Hasselbalch, HC | 1 |
| Homma, S; Ishida, F; Morita, T; Muramatsu, Y; Sugino, K; Tatebe, J | 1 |
| He, JD; Li, SP; Shen, ZY; Wang, CY; Wang, Z; Xu, HX; Xu, YJ; Yao, Z; Yu, Y; Zhang, HM; Zhang, JJ; Zhang, RX | 1 |
| Huang, T; Wang, L; Xu, G; Yan, W | 1 |
| Calzetta, L; Cazzola, M; Facciolo, F; Matera, MG; Rogliani, P | 1 |
| Chang, CY; Martin, P; Tan, HH | 1 |
| Wolters, PJ | 1 |
| Lopez, DP | 1 |
| Behr, J; Boissard, G; Buhl, R; Costabel, U; De Vuyst, P; Dekhuijzen, RP; Demedts, M; Flower, CD; Jansen, HM; Lankhorst, I; Laurent, F; MacNee, W; Nicholson, AG; Petruzzelli, S; Rodriguez-Becerra, E; Sardina, M; Thomeer, M; van den Bosch, JM; Verbeken, EK; Verschakelen, J; Wallaert, B | 1 |
| Chang, HY; Guo, YL; Lee, YH; Pan, MH; Sheu, HM; Wang, BJ; Wang, YJ | 1 |
| Moreno-Otero, R; Trapero-Marugán, M | 1 |
| Beauchesne, E; Butterworth, RF; Desjardins, P; Hazell, AS | 1 |
| Berman, AE; Brennan, AM; Kauppinen, TM; Shin, BS; Suh, SW; Swanson, RA; Won, SJ; Yoo, BH | 1 |
| Altieri, PI; Crespo, MJ; Cruz, N; Escobales, N | 1 |
| Fukaya, H; Imaki, R; Izumi, T; Machida, Y; Niwano, H; Niwano, S; Sasaki, S; Yuge, M | 1 |
| Crum, WR; Johansson, SM; Modo, M; Vernon, AC | 1 |
| Fernández-Fernández, FJ; Sesma, P | 1 |
| Naito, S; Shiota, M; Yokomizo, A | 1 |
| Ackart, DF; Basaraba, RJ; Kirk, NM; Orme, IM; Palanisamy, GS; Shanley, CA | 1 |
| Hemsworth, J; Hummelen, R; Reid, G | 1 |
| Azuma, A; Homma, S; Kudoh, S; Mochiduki, Y; Nakata, K; Ogura, T; Sugiyama, Y; Takeuchi, M; Taniguchi, H; Yoshimura, K | 1 |
| Anstrom, KJ; King, TE; Lasky, JA; Martinez, FJ; Raghu, G | 1 |
| Asevedo, E; Brietzke, E; Cunha, GR; Mansur, RB; Zugman, A | 1 |
| Bai, CX; Chen, P; Gao, Y; Kang, J; Ma, LJ; Wan, HY; Wen, FQ; Xia, QK; Yao, WZ; Zheng, JP; Zhong, NS | 1 |
| Carmichael, M | 1 |
| Dekhuijzen, PN | 1 |
| Adamy, C; Adubeiro, S; Badoual, T; Bourin, MC; Bourraindeloup, M; Cailleret, M; Candiani, G; Dubois-Rande, JL; Hittinger, L; Pecker, F; Roudot-Thoraval, F; Su, JB | 1 |
| Kobayashi, M; Maeshima, Y; Makino, H; Onoda, T; Sugiyama, H; Sunami, R; Tsukinoki, T; Yamasaki, Y | 1 |
| Akinci, SB; Aypar, U; Erden, IA; Kanbak, M | 1 |
| Chung, FL; Conaway, CC; Hecht, SS; McIntee, EJ; Pittman, B; Schwartz, JE; Tian, D; Wang, CX; Yang, YM | 1 |
| Ardia, A; De Backer, W; Decramer, M; Dekhuijzen, PN; Del Donno, M; Lankhorst, I; Olivieri, D; Pellegrino, R; Troosters, T; van Herwaarden, C; van Schayck, CP | 1 |
| Al-Osaimi, AM; Argo, CK; Caldwell, SH; Chang, CY | 1 |
| Alili, L; Brenneisen, P; Cat, B; Holtkötter, O; Sies, H; Steinbrenner, H; Stuhlmann, D | 1 |
| Cottin, V | 1 |
| Biswas, SK; de Faria, JB | 1 |
| Mehran, R | 1 |
| Anderson, MT; De Rosa, SC; Deresinski, SC; Dubs, JG; Ela, SW; Herzenberg, LA; Roederer, M | 1 |
| Hamada, J; Hosokawa, M; Kobayashi, M; Nagayasu, H; Nakata, D; Shibata, T; Takeichi, N | 1 |
| de Jong, JM; Guchelaar, HJ; Haasdijk, E; Holstege, JC; Jaarsma, D | 1 |
| Cauda, R; Ferrara, R; Lucia, BM; Malorni, W; Mazzone, AM; Paganelli, R; Rivabene, R | 1 |
| Biesalski, HK; Braun, N; Frank, J; Risler, T | 1 |
| Anderson, M; De Rosa, SC; Deresinski, SC; Dubs, JG; Ela, SW; Green, A; Herzenberg, LA; Mitra, D; Moore, WA; Nakamura, H; Parks, D; Roederer, M; Tjioe, I; Watanabe, N; Zaretsky, MD | 1 |
| Akai, H; Hamada, J; Hosokawa, M; Kobayashi, Y; Konishi, Y; Moriuchi, T; Nakae, D; Nakata, D; Okada, F; Shibata, T | 1 |
| Cadman, J; Gilden, D | 1 |
| Moyad, MA | 1 |
| Malorni, W; Masella, R; Paganelli, R; Rivabene, R; Santulli, M; Straface, E | 1 |
21 review(s) available for acetylcysteine and Disease Exacerbation
| Article | Year |
|---|---|
The Crosstalk between Prostate Cancer and Microbiota Inflammation: Nutraceutical Products Are Useful to Balance This Interplay?
Topics: Acetylcysteine; Carnitine; Chronic Disease; Dietary Supplements; Disease Progression; Fatty Acids, Unsaturated; Gastrointestinal Microbiome; Humans; Inflammation; Male; Monoterpenes; Polyphenols; Prostate; Prostatic Neoplasms | 2020 |
Impact of Mucolytic Agents on COPD Exacerbations: A Pair-wise and Network Meta-analysis.
Topics: Acetylcysteine; Ambroxol; Carbocysteine; Disease Progression; Expectorants; Humans; Network Meta-Analysis; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Thioglycolates; Thiophenes | 2017 |
Japanese guideline for the treatment of idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Disease Progression; Drug Therapy, Combination; Evidence-Based Medicine; Glycine; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Japan; Lung Neoplasms; Meta-Analysis as Topic; Practice Guidelines as Topic; Prognosis; Pyridones; Quality of Health Care; Sulfonamides; Survival Rate | 2018 |
Evaluation of the lung microbiome as a therapeutic target in the management of idiopathic pulmonary fibrosis: role of antioxidant/antibiotic combination therapy.
Topics: Acetylcysteine; Anti-Bacterial Agents; Antioxidants; Colistin; Disease Progression; Drug Synergism; Drug Therapy, Combination; Humans; Idiopathic Pulmonary Fibrosis; Lung; Microbiota | 2019 |
Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation.
Topics: Acetylcysteine; Age of Onset; Animals; Basal Ganglia; Behavior, Addictive; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Comorbidity; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Epigenomics; Free Radical Scavengers; Humans; Recurrence; Stress, Psychological | 2013 |
Effect of high/low dose N-acetylcysteine on chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Topics: Acetylcysteine; Antioxidants; Disease Progression; Forced Expiratory Volume; Humans; Pulmonary Disease, Chronic Obstructive | 2014 |
An update for the controversies and hypotheses of regulating nonthyroidal illness syndrome in chronic kidney diseases.
Topics: Acetylcysteine; Comorbidity; Cytokines; Disease Progression; Euthyroid Sick Syndromes; Hormone Replacement Therapy; Humans; Oxidative Stress; Renal Insufficiency, Chronic; Sodium Bicarbonate; Thyroid Hormones | 2014 |
Oxidative stress and respiratory system: pharmacological and clinical reappraisal of N-acetylcysteine.
Topics: Acetylcysteine; Antioxidants; Bronchitis, Chronic; Disease Progression; Expectorants; Forced Expiratory Volume; Hospitalization; Humans; Macrophages; Neutrophils; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Respiratory Physiological Phenomena | 2014 |
Update on the pathological processes, molecular biology, and clinical utility of N-acetylcysteine in chronic obstructive pulmonary disease.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Progression; Dose-Response Relationship, Drug; Humans; Lung; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quality of Life; Severity of Illness Index; Treatment Outcome | 2014 |
Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Comparative Effectiveness Research; Disease Progression; Drug Therapy, Combination; Free Radical Scavengers; Hepatitis, Alcoholic; Humans; Pentoxifylline; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome | 2015 |
Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis.
Topics: Acetylcysteine; Bronchitis, Chronic; Bronchodilator Agents; Disease Progression; Humans; Lung; Pulmonary Disease, Chronic Obstructive; Treatment Outcome | 2015 |
The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms.
Topics: Acetylcysteine; Animals; Antioxidants; Disease Progression; Hepatitis C; Humans; Inflammation; Mice; Myeloproliferative Disorders; Neoplasms; Oxidative Stress; Primary Myelofibrosis; Reactive Oxygen Species; Signal Transduction | 2015 |
Emergency: acetaminophen poisoning.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Disease Progression; Drug Labeling; Emergencies; Emergency Treatment; Female; Humans; Liver Diseases; Nonprescription Drugs; Patient Education as Topic; Risk Factors; Substance Abuse Detection; Suicide, Attempted; Time Factors | 2009 |
Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer.
Topics: Acetylcysteine; Androgen Antagonists; Androgens; Animals; Antioxidants; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Progression; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Male; Mice; Mutation; Orchiectomy; Oxidative Stress; Prostate; Prostatic Neoplasms; Protein Isoforms; Receptors, Androgen; Signal Transduction | 2011 |
Micronutrients, N-acetyl cysteine, probiotics and prebiotics, a review of effectiveness in reducing HIV progression.
Topics: Acetylcysteine; Child; Dietary Supplements; Disease Progression; Female; Free Radical Scavengers; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Micronutrients; Prebiotics; Pregnancy; Pregnancy Complications, Infectious; Probiotics; Randomized Controlled Trials as Topic | 2010 |
N-acetylcysteine as a potentially useful medication to prevent conversion to schizophrenia in at-risk individuals.
Topics: Acetylcysteine; Animals; Disease Progression; Free Radical Scavengers; Humans; Risk; Schizophrenia | 2012 |
Antioxidant properties of N-acetylcysteine: their relevance in relation to chronic obstructive pulmonary disease.
Topics: Acetylcysteine; Antioxidants; Disease Progression; Free Radical Scavengers; Humans; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species | 2004 |
Therapy of NAFLD: antioxidants and cytoprotective agents.
Topics: Acetylcysteine; Antioxidants; Betaine; Cholagogues and Choleretics; Disease Progression; Fatty Liver; Humans; Lipid Peroxidation; S-Adenosylmethionine; Ursodeoxycholic Acid; Vitamin E | 2006 |
[Idiopathic interstitial pneumonia: treatment].
Topics: Acetylcysteine; Acute Disease; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Azathioprine; Benzamides; Bronchiolitis Obliterans; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colchicine; Cyclophosphamide; Diagnosis, Differential; Disease Progression; Female; Free Radical Scavengers; Humans; Imatinib Mesylate; Immunologic Factors; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Middle Aged; Piperazines; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyrimidines; Randomized Controlled Trials as Topic; Retrospective Studies; Sex Factors | 2006 |
Contrast-induced nephropathy remains a serious complication of PCI.
Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Contrast Media; Disease Progression; Fenoldopam; Humans; Incidence; Kidney Diseases; Prognosis; Risk Factors; Sodium Bicarbonate | 2007 |
Results and lessons from clinical trials using dietary supplements for cancer: direct and indirect investigations.
Topics: Acetylcysteine; Amygdalin; Antioxidants; Ascorbic Acid; beta Carotene; Dietary Supplements; Disease Progression; Humans; Neoplasms; Randomized Controlled Trials as Topic; Selenium; Tissue Extracts; Vitamin A; Vitamin E | 2001 |
14 trial(s) available for acetylcysteine and Disease Exacerbation
| Article | Year |
|---|---|
Comparative Study to Evaluate the Effect of Low-Protein Diet Supplementation with Taurine and N-Acetylcysteine, N-Acetylcysteine and Pyridoxamine Dihydrochloride in Preventing the Progression of Chronic Renal Failure in Patients with Non-Diabetic Kidney D
Topics: Acetylcysteine; Adult; Aged; Diet, Protein-Restricted; Dietary Supplements; Disease Progression; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pyridoxamine; Renal Insufficiency, Chronic; Taurine | 2022 |
A randomized, double-blind, placebo-controlled study evaluating the efficacy of propolis and N-acetylcysteine in exacerbations of chronic obstructive pulmonary disease.
Topics: Acetylcysteine; Disease Progression; Double-Blind Method; Humans; Propolis; Pulmonary Disease, Chronic Obstructive | 2022 |
N-Acetyl Cysteine as a Neuroprotective Agent in Progressive Multiple Sclerosis (NACPMS) trial: Study protocol for a randomized, double-blind, placebo-controlled add-on phase 2 trial.
Topics: Acetylcysteine; Clinical Trials, Phase II as Topic; Disease Progression; Double-Blind Method; Humans; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Neuroprotective Agents; Randomized Controlled Trials as Topic; Treatment Outcome | 2022 |
Impact of smoking status and concomitant medications on the effect of high-dose N-acetylcysteine on chronic obstructive pulmonary disease exacerbations: A post-hoc analysis of the PANTHEON study.
Topics: Acetylcysteine; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adrenergic beta-2 Receptor Agonists; Aged; Bronchodilator Agents; China; Disease Progression; Expectorants; Female; Humans; Male; Middle Aged; Placebos; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Smoking | 2019 |
Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Aged; Azathioprine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Male; Middle Aged; Prednisone; Treatment Failure; Vital Capacity | 2014 |
Treatment for non-thyroidal illness syndrome in advanced chronic kidney disease: a single-blind controlled study.
Topics: Acetylcysteine; Chi-Square Distribution; China; Disease Progression; Euthyroid Sick Syndromes; Female; Glomerular Filtration Rate; Humans; Kaplan-Meier Estimate; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Proportional Hazards Models; Renal Insufficiency, Chronic; Risk Factors; Single-Blind Method; Sodium Bicarbonate; Time Factors; Treatment Outcome | 2017 |
Lung function in idiopathic pulmonary fibrosis--extended analyses of the IFIGENIA trial.
Topics: Acetylcysteine; Aged; Azathioprine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Europe; Exercise Test; Female; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Patient Dropouts; Prednisone; Pulmonary Diffusing Capacity; Respiratory System Agents; Severity of Illness Index; Time Factors; Treatment Outcome; Vital Capacity | 2009 |
Efficacy of inhaled N-acetylcysteine monotherapy in patients with early stage idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Administration, Inhalation; Aged; Asian People; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Severity of Illness Index; Treatment Outcome; Vital Capacity | 2012 |
Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis.
Topics: Acetylcysteine; Aged; Azathioprine; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Female; Hospitalization; Humans; Kaplan-Meier Estimate; Male; Medication Adherence; Middle Aged; Prednisone; Pulmonary Fibrosis; Treatment Outcome; Vital Capacity | 2012 |
High-dose N-acetylcysteine in the prevention of COPD exacerbations: rationale and design of the PANTHEON Study.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Disease Progression; Double-Blind Method; Expectorants; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality of Life; Research Design; Time Factors; Vital Capacity | 2013 |
Lack of effect of N-acetylcysteine treatment to ameliorate the progression of multiple organ failure.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Disease Progression; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Prospective Studies | 2005 |
Quality control of spirometry: a lesson from the BRONCUS trial.
Topics: Acetylcysteine; Aged; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Forced Expiratory Volume; Humans; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quality Control; Reference Values; Respiratory Function Tests; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Spirometry | 2005 |
Glutathione deficiency is associated with impaired survival in HIV disease.
Topics: Acetylcysteine; Biomarkers; CD4-Positive T-Lymphocytes; Cell Survival; Cohort Studies; Disease Progression; Glutathione; HIV Infections; Humans; Pyrazoles; Regression Analysis; Survival Analysis; Survival Rate | 1997 |
N-acetylcysteine replenishes glutathione in HIV infection.
Topics: Acetylcysteine; Adult; Antiviral Agents; Disease Progression; Double-Blind Method; Glutathione; HIV Infections; Humans; Male; Survival Analysis | 2000 |
57 other study(ies) available for acetylcysteine and Disease Exacerbation
| Article | Year |
|---|---|
Efficacy of treatment with N-acetylcysteine inhalation for AECOPD: A propensity-score-matched cohort study.
Topics: Acetylcysteine; Cohort Studies; Disease Progression; Humans; Propensity Score; Pulmonary Disease, Chronic Obstructive; Retrospective Studies | 2023 |
Oral administration of N-acetyl cysteine prevents osteoarthritis development and progression in a rat model.
Topics: Acetylcysteine; Administration, Oral; Aged; Animals; Apoptosis; Arthritis, Experimental; Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagen Type II; Cytokines; Disease Progression; Drug Evaluation, Preclinical; Humans; Male; Matrix Metalloproteinase 13; Osteoarthritis, Knee; Primary Cell Culture; Rats; Reactive Oxygen Species; Stress, Mechanical | 2019 |
N-acetylcysteine (NAC), an anti-oxidant, does not improve bone mechanical properties in a rat model of progressive chronic kidney disease-mineral bone disorder.
Topics: Acetylcysteine; Animals; Antioxidants; Caseins; Chronic Kidney Disease-Mineral and Bone Disorder; Disease Models, Animal; Disease Progression; Glycation End Products, Advanced; Humans; Kidney; Lipid Peroxidation; Male; Mutation; Nuclear Proteins; Oxidative Stress; Parathyroid Hormone; Rats; Tibia; X-Ray Microtomography | 2020 |
NAD(P)HX epimerase downregulation promotes tumor progression through ROS/HIF-1α signaling in hepatocellular carcinoma.
Topics: Acetylcysteine; Analysis of Variance; Animals; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Disease-Free Survival; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Free Radical Scavengers; Heterografts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Male; Mice; Middle Aged; NADP; Neoplasm Invasiveness; Neoplasm Proteins; Neoplasm Transplantation; Oxidation-Reduction; Racemases and Epimerases; Reactive Oxygen Species; Risk Factors | 2021 |
Protective effect of N-acetylcysteine on progression to end-stage renal disease: Necessity for prospective clinical trial.
Topics: Acetylcysteine; Adolescent; Adult; Comorbidity; Disease Progression; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Male; Middle Aged; Multivariate Analysis; Propensity Score; Renal Dialysis; Renal Insufficiency, Chronic; Retrospective Studies; Risk Factors; Risk Reduction Behavior; Survival Analysis; Taiwan; Young Adult | 2017 |
N-acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminopyridines; Analgesics; Antidotes; Biomarkers; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Progression; Drug Therapy, Combination; Female; Glucocorticoids; Glutathione; Hepatocytes; Humans; Infusions, Intravenous; Liver; Liver Transplantation; Male; Middle Aged; Prednisolone; Recovery of Function; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2018 |
Alterations in Acrolein Metabolism Contribute to Alzheimer's Disease.
Topics: Acetylcysteine; Acrolein; Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Case-Control Studies; Creatinine; Disease Progression; Early Diagnosis; Female; Humans; Male; Middle Aged | 2018 |
N-acetyl-cysteine increases cellular dysfunction in progressive chronic kidney damage after acute kidney injury by dampening endogenous antioxidant responses.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Proliferation; Disease Models, Animal; Disease Progression; Energy Metabolism; Kidney; Male; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Mitochondria; NAD; Oxidative Stress; Phosphorylation; PPAR gamma; Renal Insufficiency, Chronic; Signal Transduction; Time Factors; Transforming Growth Factor beta1 | 2018 |
N-Acetylcysteine protects human bronchi by modulating the release of neurokinin A in an ex vivo model of COPD exacerbation.
Topics: Acetylcysteine; Biological Availability; Bronchi; Disease Progression; Female; Humans; Inflammation; Lipopolysaccharides; Male; Middle Aged; Models, Biological; Neurokinin A; Oxidative Stress; Protective Agents; Pulmonary Disease, Chronic Obstructive; Regression Analysis | 2018 |
Effect of tadalafil on reduction of necrosis in the ischemic zone in a rat comb burn model.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Disease Models, Animal; Disease Progression; Free Radical Scavengers; Ischemia; Naproxen; Necrosis; Random Allocation; Rats; Rats, Sprague-Dawley; Skin; Tadalafil; Vasodilator Agents | 2018 |
Reactive oxygen species stimulated pulmonary epithelial cells mediate the alveolar recruitment of FasL
Topics: Acetylcysteine; Acute Lung Injury; Alveolar Epithelial Cells; Animals; Apoptosis; B-Lymphocyte Subsets; Bronchoalveolar Lavage Fluid; Chemokine CXCL10; Chemokine CXCL9; Chemotaxis, Leukocyte; Cytotoxicity, Immunologic; Disease Progression; Fas Ligand Protein; Female; Free Radical Scavengers; Lipopolysaccharides; Lung; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Second Messenger Systems | 2018 |
Using the 150 rule to prevent hepatotoxicity from acetaminophen.
Topics: Acetaminophen; Acetylcysteine; Adolescent; Diagnosis, Differential; Disease Progression; Drug Overdose; Female; Humans; Liver Failure, Acute | 2019 |
Efficacy of TCM therapy of tonifying lung-kidney's Qi-deficiency in a case of idiopathic pulmonary fibrosis: A case report.
Topics: Acetylcysteine; Carbon Monoxide; Disease Progression; Expectorants; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; Kidney; Lung; Male; Medicine, Chinese Traditional; Middle Aged; Pulmonary Diffusing Capacity; Respiratory Function Tests; Treatment Outcome; Vital Capacity; Yin Deficiency | 2019 |
p66Shc protein through a redox mechanism enhances the progression of prostate cancer cells towards castration-resistance.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Hydrogen Peroxide; Kallikreins; Lymphatic Metastasis; Male; Mice; Mice, Nude; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Reactive Oxygen Species; Receptors, Androgen; Src Homology 2 Domain-Containing, Transforming Protein 1 | 2019 |
A role for reactive oxygen species in JAK2 V617F myeloproliferative neoplasm progression.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Bone Marrow Transplantation; Case-Control Studies; Disease Progression; DNA Damage; Female; Flow Cytometry; Hematopoietic Stem Cells; Humans; Immunoenzyme Techniques; Janus Kinase 2; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloproliferative Disorders; Point Mutation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2013 |
Guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis. Sociedad Española de Neumología y Cirugía Torácica (SEPAR) Research Group on Diffuse Pulmonary Diseases.
Topics: Acetylcysteine; Biopsy; Bronchoalveolar Lavage Fluid; Cell- and Tissue-Based Therapy; Clinical Trials as Topic; Contraindications; Diagnostic Imaging; Disease Progression; Evidence-Based Medicine; Gastroesophageal Reflux; Genetic Therapy; Glucocorticoids; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Immunologic Factors; Incidence; Indoles; Lung; Lung Transplantation; Oxygen Inhalation Therapy; Palliative Care; Prevalence; Prognosis; Pulmonary Emphysema; Pyridones; Risk Factors; Spain | 2013 |
Antioxidant N-acetylcysteine attenuates hepatocarcinogenesis by inhibiting ROS/ER stress in TLR2 deficient mouse.
Topics: Acetylcysteine; Animals; Antioxidants; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line; Diethylnitrosamine; Disease Progression; Endoplasmic Reticulum Stress; Liver Neoplasms; Male; Mice; Reactive Oxygen Species; Signal Transduction; Toll-Like Receptor 2 | 2013 |
Efficacy of pirfenidone in patients with advanced-stage idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Administration, Inhalation; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Disease Progression; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2013 |
A ROS/STAT3/HIF-1α signaling cascade mediates EGF-induced TWIST1 expression and prostate cancer cell invasion.
Topics: Acetylcysteine; Cadherins; Cell Line, Tumor; Cell Movement; Disease Progression; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Neoplasm Invasiveness; Nuclear Proteins; Phosphorylation; Prostatic Neoplasms; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Twist-Related Protein 1 | 2014 |
Antioxidants accelerate lung cancer progression in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Disease Progression; DNA Damage; Fibroblasts; Humans; Lung Neoplasms; Mice; Reactive Oxygen Species; Solubility; Tumor Suppressor Protein p53; Vitamin E | 2014 |
Reactive oxygen species prevent imiquimod-induced psoriatic dermatitis through enhancing regulatory T cell function.
Topics: Acetylcysteine; Aminoquinolines; Animals; Dermatitis; Disease Progression; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hyperbaric Oxygenation; Imiquimod; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice, Inbred C57BL; NADPH Oxidases; Naphthoquinones; Psoriasis; Reactive Oxygen Species; T-Lymphocytes, Regulatory | 2014 |
Up-regulation of β-amyloidogenesis in neuron-like human cells by both 24- and 27-hydroxycholesterol: protective effect of N-acetyl-cysteine.
Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Disease Progression; Humans; Hydroxycholesterols; Neurons; Oxidative Stress; Up-Regulation | 2014 |
Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.
Topics: Acetylcysteine; Analysis of Variance; Animals; Carrier Proteins; Caspase 1; Conjunctiva; Cornea; Disease Models, Animal; Disease Progression; Dry Eye Syndromes; Enzyme-Linked Immunosorbent Assay; Female; Free Radical Scavengers; Inflammasomes; Interleukin-1beta; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction | 2014 |
Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression.
Topics: Acetylcysteine; Animals; Apolipoprotein A-I; Atherosclerosis; Bone Marrow Transplantation; Cell Division; Diet, Atherogenic; Disease Progression; Hematopoietic Stem Cells; Humans; Hypercholesterolemia; Leukocytosis; Lipoproteins, HDL; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Radiation Chimera; Reactive Oxygen Species; Receptors, LDL; Scavenger Receptors, Class B | 2014 |
Pirfenidone in idiopathic pulmonary fibrosis: real-life experience from a German tertiary referral center for interstitial lung diseases.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Disease Progression; Drug Eruptions; Drug Therapy, Combination; Expectorants; Fatigue; Female; Gastrointestinal Diseases; Germany; Humans; Idiopathic Pulmonary Fibrosis; Male; Medication Adherence; Middle Aged; Pyridones; Retrospective Studies; Tertiary Care Centers; Treatment Outcome; Vital Capacity; Weight Loss | 2014 |
N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Free Radical Scavengers; Gait; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Organ Size; Oxidative Stress | 2015 |
Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation.
Topics: Acetylcysteine; Animals; Apoptosis; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Cardiomyopathy, Dilated; Cells, Cultured; Disease Progression; Gene Expression Profiling; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Failure; Ion Channels; Male; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Proteins; Myocytes, Cardiac; Oxidative Stress; Point Mutation; PPAR alpha; Pressure; Rats; Reactive Oxygen Species; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sequence Analysis, RNA; Sulfonamides; Transfection; Uncoupling Protein 3 | 2015 |
[Two drugs inhibit disease progression. Idiopathic lung fibrosis treatable for the first time].
Topics: Acetylcysteine; Disease Progression; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Survival Analysis; Vital Capacity | 2015 |
Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes.
Topics: Acetylcysteine; Aged; Antioxidants; Disease Progression; Drug Administration Schedule; Epoxide Hydrolases; Female; Forced Expiratory Volume; Humans; Lung; Male; Middle Aged; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Pulmonary Disease, Chronic Obstructive; Recovery of Function; Severity of Illness Index; Spirometry; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2015 |
Brodifacoum induces early hemoglobinuria and late hematuria in rats: novel rapid biomarkers of poisoning.
Topics: 4-Hydroxycoumarins; Acetylcysteine; Animals; Biomarkers; Disease Progression; Free Radical Scavengers; Hematuria; Hemoglobins; Hemoglobinuria; Rats; Rats, Sprague-Dawley; Rodenticides | 2015 |
Effect of inhaled N-acetylcysteine monotherapy on lung function and redox balance in idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Administration, Inhalation; Aged; Disease Progression; Female; Glutathione; Glutathione Disulfide; Humans; Idiopathic Pulmonary Fibrosis; Male; Retrospective Studies; ROC Curve; Vital Capacity | 2016 |
LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway.
Topics: Acetylcysteine; Aged; Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epithelial-Mesenchymal Transition; Female; Humans; Lentivirus; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; RNA, Long Noncoding; RNA, Small Interfering; Signal Transduction; Zinc Finger E-box-Binding Homeobox 1 | 2016 |
Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation.
Topics: Acetylcysteine; Aged; Airway Resistance; Anti-Inflammatory Agents; Antioxidants; Disease Progression; Female; Humans; Lung; Male; Organ Culture Techniques; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Reactive Oxygen Species; Treatment Outcome | 2017 |
Acetaminophen hepatotoxicity: current management.
Topics: Acetaminophen; Acetylcysteine; Antidotes; Charcoal; Chemical and Drug Induced Liver Injury; Cimetidine; Comorbidity; Disease Progression; Drug and Narcotic Control; Free Radical Scavengers; Humans; Liver Failure; Liver Transplantation; Prognosis; Renal Dialysis; Severity of Illness Index; Treatment Outcome | 2009 |
Could N-acetylcysteine slow progression of idiopathic pulmonary fibrosis by inhibiting EMT?
Topics: Acetylcysteine; Animals; Disease Progression; Drug Therapy, Combination; Epithelium; Humans; Idiopathic Pulmonary Fibrosis; Mesoderm; Pulmonary Alveoli; Rats | 2009 |
N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species.
Topics: Acetylcysteine; Animals; Antioxidants; Chromium; Dermatitis, Allergic Contact; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Female; Glutathione; Guinea Pigs; Hydrogen Peroxide; Malondialdehyde; Reactive Oxygen Species; Severity of Illness Index; Skin | 2010 |
Hepatoprotective effects of antioxidants in chronic hepatitis C.
Topics: Acetylcysteine; Antioxidants; Disease Progression; Fatty Liver; Fibrosis; Hepacivirus; Hepatitis C, Chronic; Humans; Liver; Nitric Oxide; Oxidative Stress; S-Adenosylmethionine; Virus Replication | 2010 |
Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency.
Topics: Acetylcysteine; Animals; Blood-Brain Barrier; Caveolin 1; Disease Progression; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Random Allocation; Signal Transduction; Thiamine Deficiency; Up-Regulation | 2010 |
EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia.
Topics: Acetylcysteine; Animals; Disease Progression; Excitatory Amino Acid Transporter 3; Gene Deletion; Homeostasis; Ischemic Attack, Transient; Male; Mice; Mice, Transgenic; Neurons; Zinc | 2010 |
Chronic treatment with N-acetylcysteine improves cardiac function but does not prevent progression of cardiomyopathy in Syrian cardiomyopathic hamsters.
Topics: Acetylcholine; Acetylcysteine; Age Factors; Animals; Antioxidants; Aorta, Thoracic; Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Disease Progression; Echocardiography; Heart Failure; Male; Mesocricetus; Oxidative Stress; Time Factors | 2011 |
N-acetylcysteine suppresses the progression of ventricular remodeling in acute myocarditis: studies in an experimental autoimmune myocarditis (EAM) model.
Topics: Acetylcysteine; Acute Disease; Animals; Autoimmune Diseases; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Free Radical Scavengers; Injections, Intraperitoneal; Myocarditis; Oxidative Stress; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Ventricular Remodeling | 2011 |
Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease.
Topics: Acetylcysteine; Animals; Behavior, Animal; Corpus Striatum; Cysteine Proteinase Inhibitors; Disease Models, Animal; Disease Progression; Male; Mental Disorders; Motor Activity; Parkinson Disease, Secondary; Prognosis; Proteasome Inhibitors; Rats; Rats, Sprague-Dawley; Substantia Nigra | 2011 |
Acetylcysteine as adjuvant therapy for vasculitis associated with antineutrophil cytoplasmic antibody.
Topics: Acetylcysteine; Antibodies, Antineutrophil Cytoplasmic; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease Progression; Free Radical Scavengers; Humans; Male; Middle Aged; Vasculitis | 2011 |
Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis.
Topics: Acetylcysteine; Animals; Antioxidants; Bacterial Load; Disease Progression; Gene Expression Regulation; Glutathione; Guinea Pigs; Lung; Malondialdehyde; Mycobacterium bovis; Mycobacterium tuberculosis; NF-E2-Related Factor 2; Oxidative Stress; Tuberculosis; Vaccination | 2011 |
Ginkgo on your mind? It may ease dementia, but nothing's definite.
Topics: Acetylcysteine; Dementia; Disease Progression; Ginkgo biloba; Humans; Phytotherapy; Plant Extracts; United States | 2002 |
N-acetylcysteine treatment normalizes serum tumor necrosis factor-alpha level and hinders the progression of cardiac injury in hypertensive rats.
Topics: Acetylcysteine; Animals; Antioxidants; Collagen; Disease Progression; Drug Evaluation, Preclinical; Glutathione; Heart Ventricles; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Sodium Chloride, Dietary; Sphingomyelin Phosphodiesterase; Tumor Necrosis Factor-alpha; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Remodeling | 2004 |
Mesangial cell Fas ligand: upregulation in human lupus nephritis and NF-kappaB-mediated expression in cultured human mesangial cells.
Topics: Acetylcysteine; Cells, Cultured; Cysteine Proteinase Inhibitors; Cytokines; Disease Progression; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Fas Ligand Protein; Glomerular Mesangium; Humans; Immunohistochemistry; Indicators and Reagents; Inflammation Mediators; Interleukin-1; Lupus Nephritis; Matrix Metalloproteinase 7; Membrane Glycoproteins; Microscopy, Confocal; Microscopy, Electron; NF-kappa B; Nuclear Proteins; Up-Regulation | 2004 |
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Topics: Acetylcysteine; Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Body Weight; Carcinogens; Caspase 3; Caspases; Cell Growth Processes; Disease Progression; Female; In Situ Nick-End Labeling; Isothiocyanates; Lung Neoplasms; Mice; Mice, Inbred A; Nitrosamines; Smoking; Sulfoxides; Thiocyanates | 2005 |
Enhancement of tumor invasion depends on transdifferentiation of skin fibroblasts mediated by reactive oxygen species.
Topics: Acetylcysteine; Antioxidants; Cell Differentiation; Cells, Cultured; Chromans; Disease Progression; Fibroblasts; Humans; Lipid Peroxidation; Models, Biological; Muscle Fibers, Skeletal; Neoplasm Invasiveness; Protein Kinase C; Reactive Oxygen Species; Skin; Smad Proteins; Sodium Selenite; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Which comes first: renal inflammation or oxidative stress in spontaneously hypertensive rats?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Age Factors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; Disease Models, Animal; Disease Progression; DNA Damage; Glutathione; Hypertension; Kidney Cortex; Male; NADPH Oxidases; Nephritis; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Tyrosine | 2007 |
Reversible and irreversible tumor progression of a weakly malignant rat mammary carcinoma cell line by in vitro exposure to epidermal growth factor.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Disease Progression; DNA Damage; DNA Primers; Epidermal Growth Factor; ErbB Receptors; Female; Flow Cytometry; Free Radical Scavengers; In Vitro Techniques; Mammary Neoplasms, Experimental; Microscopy, Confocal; Neoplasm Invasiveness; Oxidative Stress; Peroxides; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 1998 |
The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Acetylcysteine; Administration, Oral; Amyotrophic Lateral Sclerosis; Animals; Body Weight; Disease Progression; Free Radical Scavengers; Half-Life; Mice; Mice, Transgenic; Point Mutation; Vitamin E | 1998 |
The role of oxidative imbalance in progression to AIDS: effect of the thiol supplier N-acetylcysteine.
Topics: Acetylcysteine; Acquired Immunodeficiency Syndrome; Adult; Antioxidants; Cells, Cultured; Disease Progression; Female; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress; Sulfhydryl Compounds | 1998 |
Antioxidative treatment retards progression of idiopathic membranous nephropathy.
Topics: Acetylcysteine; Adult; Antioxidants; Ascorbic Acid; beta Carotene; Complement Membrane Attack Complex; Disease Progression; Glomerulonephritis, Membranous; Humans; Kidney; Male; Selenium; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E | 2000 |
Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenocarcinoma; Animals; Antioxidants; Deoxyguanosine; Disease Progression; DNA Damage; Epidermal Growth Factor; Female; Free Radical Scavengers; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Microscopy, Confocal; Oxidative Stress; Rats; Rats, Inbred SHR; Selenium; Tumor Cells, Cultured | 2001 |
A NAC for controversy.
Topics: Acetylcysteine; CD4 Lymphocyte Count; Clinical Trials, Phase I as Topic; Disease Progression; Female; Glutathione; HIV Infections; Humans; Male; United States; Viral Load | 1997 |
Structural changes of the erythrocyte as a marker of non-insulin-dependent diabetes: protective effects of N-acetylcysteine.
Topics: Acanthocytes; Acetylcysteine; Aged; Aged, 80 and over; Antioxidants; Cell Size; Cytoskeleton; Diabetes Mellitus, Type 2; Disease Progression; Erythrocyte Membrane; Erythrocytes; Female; Glutathione; Humans; Microscopy, Electron, Scanning; Receptor, Insulin; Spectrin | 2002 |