acetylcysteine and Diabetes Mellitus

acetylcysteine has been researched along with Diabetes Mellitus in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (53.85)29.6817
2010's5 (19.23)24.3611
2020's7 (26.92)2.80

Authors

AuthorsStudies
Chen, W; Guo, J; Han, Q; Hu, L; Li, H; Li, Q; Li, Y; Liao, J; Ma, F; Pan, J; Tang, Z; Zhang, H; Zhang, K1
Chang, YP; Cheng, HW; Kuo, CW; Lin, CC; Liu, WS; Lu, SH; Tong, ZJ; Tsai, MT; Tsou, HH; Wang, HT; Yen, PC1
Guo, J; Han, Q; Hu, L; Huo, H; Li, H; Li, Y; Liao, J; Ma, F; Pan, J; Tang, Z; Zhang, H1
Ahamed, AI; Kim, J; Li, X; Martins-Green, M; Wang, Y; Wu, J1
Mehrbani Azar, Y; Niesler, CU; van de Vyver, M1
Chen, J; Hong, Z; Lin, Y; Ni, L; Shao, Z; Shi, Y; Sun, L; Tian, N; Wang, B; Wang, X; Wu, A; Wu, Y; Zhang, X; Zhou, Y1
Chen, J; Fan, F; Guo, M; Jiang, C; Long, Y; Tang, S; Wang, Y; Xu, Y1
Grider, JR; Mahavadi, S; Manion, O; Murthy, KS; Sriwai, W1
Li, M; Sun, L; Wu, X; Yu, J; Zhang, X1
Aleksiejuk, P; Banki, K; Bonilla, E; Francis, L; Landas, SK; Liu, Y; Marchena-Mendez, I; Oaks, Z; Patel, J; Perl, A; Yu, J1
Ato, M; Bancroft, GJ; Kewcharoenwong, C; Lertmemongkolchai, G; Nithichanon, A; Rinchai, D1
Abboud, HE; Gorin, Y; Habib, SL; Simone, S; Velagapudi, C1
Chae, IH; Choi, DJ; Choi, YS; Jo, SH; Kang, HJ; Kim, HL; Kim, HS; Kim, YJ; Koo, BK; Oh, BH; Park, JS; Park, YB; Sohn, DW1
Amini, M; Amirbaigloo, A; Esfahani, F; Masoudkabir, F; Salarifar, M1
Grutzmacher, C; Morrison, ME; Park, S; Sheibani, N; Sorenson, CM; Zhao, Y1
Jain, AK; Jain, SK; Langford, M; Lim, G1
Delvin, E; Lambert, M; Levy, E; Seidman, E; Ziv, E; Zoltowska, M1
Chou, JY; Mansfield, BC; Pan, CJ; Shieh, JJ1
Cai, W; He, JC; Lu, C; Peppa, M; Uribarri, J; Vlassara, H; Zhu, L1
Hsieh, CH; Hsu, CC; Tsai, CM; Yen, HF; Yin, MC1
Abbott, KC; Coyle, LC; Jeschke, RE; Rodriguez, A; Simon-Lee, A; Taylor, AJ1
Hamada, Y; Hazaka, Y; Ichijo, H; Kani, S; Minami, Y; Nakayama, E; Onishi, N; Sougawa, N; Takeda, K; Umeda, T; Yoda, A1
Zhang, J1
Dangas, G; Mehran, R; Pucelikova, T1
Giacca, A; Lewis, GF; Xiao, C1
Brunet, S; Comte, B; Guéraud, F; Huot, C; Jacob, SV; Krishnamoorthy, P; Lands, LC; Legault, L; Levy, E; Ntimbane, T1

Reviews

1 review(s) available for acetylcysteine and Diabetes Mellitus

ArticleYear
Contrast-induced nephropathy.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Jan-01, Volume: 71, Issue:1

    Topics: Acetylcysteine; Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Coronary Angiography; Creatinine; Diabetes Mellitus; Fenoldopam; Free Radical Scavengers; Heart Failure; Humans; Iatrogenic Disease; Kidney Diseases; Kidney Transplantation; Multivariate Analysis; Osmolar Concentration; Phosphodiesterase Inhibitors; Prognosis; Renal Dialysis; Risk Factors; Theophylline

2008

Trials

5 trial(s) available for acetylcysteine and Diabetes Mellitus

ArticleYear
N-acetyl-L-cysteine alleviates FUNDC1-mediated mitophagy by regulating mitochondrial dynamics in type 1 diabetic nephropathy canine.
    Life sciences, 2023, Jan-15, Volume: 313

    Topics: Acetylcysteine; Animals; Diabetes Mellitus; Diabetic Nephropathies; Dogs; Insulins; Mitochondrial Dynamics; Mitochondrial Proteins; Mitophagy

2023
N-acetylcysteine versus AScorbic acid for preventing contrast-Induced nephropathy in patients with renal insufficiency undergoing coronary angiography NASPI study-a prospective randomized controlled trial.
    American heart journal, 2009, Volume: 157, Issue:3

    Topics: Acetylcysteine; Aged; Antioxidants; Ascorbic Acid; Comorbidity; Contrast Media; Coronary Angiography; Creatinine; Diabetes Mellitus; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency

2009
N-acetylcysteine does not prevent contrast-induced nephropathy after cardiac catheterization in patients with diabetes mellitus and chronic kidney disease: a randomized clinical trial.
    Trials, 2009, Jun-29, Volume: 10

    Topics: Acetylcysteine; Administration, Oral; Aged; Cardiac Catheterization; Contrast Media; Coronary Angiography; Creatinine; Diabetes Mellitus; Female; Free Radical Scavengers; Humans; Incidence; Kidney Diseases; Male; Middle Aged; Placebos; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors

2009
High levels of dietary advanced glycation end products transform low-density lipoprotein into a potent redox-sensitive mitogen-activated protein kinase stimulant in diabetic patients.
    Circulation, 2004, Jul-20, Volume: 110, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Antioxidants; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Endothelium, Vascular; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Glycation End Products, Advanced; Humans; Lipoproteins, LDL; Male; Middle Aged; NADPH Oxidases; NF-kappa B; Oxidation-Reduction; Transcriptional Activation; Vascular Cell Adhesion Molecule-1

2004
Acetylcysteine In Diabetes (AID): a randomized study of acetylcysteine for the prevention of contrast nephropathy in diabetics.
    American heart journal, 2006, Volume: 151, Issue:5

    Topics: Acetylcysteine; Administration, Oral; Aged; Contrast Media; Coronary Angiography; Creatinine; Diabetes Mellitus; Drug Administration Schedule; Female; Humans; Incidence; Injections, Intravenous; Kidney Diseases; Male; Middle Aged; Sodium Chloride; Treatment Failure

2006

Other Studies

20 other study(ies) available for acetylcysteine and Diabetes Mellitus

ArticleYear
NAC alleviative ferroptosis in diabetic nephropathy via maintaining mitochondrial redox homeostasis through activating SIRT3-SOD2/Gpx4 pathway.
    Free radical biology & medicine, 2022, Volume: 187

    Topics: Acetylcysteine; Animals; Diabetes Mellitus; Diabetic Nephropathies; Dogs; Ferroptosis; Homeostasis; Insulins; Mammals; Mitochondria; Oxidation-Reduction; Sirtuin 3

2022
Acrolein plays a culprit role in the pathogenesis of diabetic nephropathy in vitro and in vivo.
    European journal of endocrinology, 2022, Oct-01, Volume: 187, Issue:4

    Topics: Acetylcysteine; Acrolein; Animals; Carnosine; Cytokines; Diabetes Mellitus; Diabetic Nephropathies; Environmental Pollutants; HEK293 Cells; Humans; Hydralazine; Kidney; Mice; Streptozocin

2022
    Journal of diabetes research, 2020, Volume: 2020

    Topics: Acetylcysteine; Animals; Biofilms; Chronic Disease; Diabetes Mellitus; Disease Models, Animal; DNA, Bacterial; Extracellular Polymeric Substance Matrix; Free Radical Scavengers; Hydrogen-Ion Concentration; In Vitro Techniques; Mice; Mice, Obese; Microbial Viability; Microscopy, Confocal; Microscopy, Fluorescence; Oxidative Stress; Protein Biosynthesis; Pseudomonas aeruginosa; Pseudomonas Infections; Wound Infection; Wounds and Injuries

2020
Ex vivo antioxidant preconditioning improves the survival rate of bone marrow stem cells in the presence of wound fluid.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2020, Volume: 28, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Case-Control Studies; Cell Movement; Cell Proliferation; Cell Survival; Diabetes Mellitus; Exudates and Transudates; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Obese; Osteogenesis; Prediabetic State; Transplantation, Autologous; Wounds and Injuries

2020
High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes.
    Cell death & disease, 2021, 05-18, Volume: 12, Issue:6

    Topics: Acetylcysteine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Autophagy; Chondrocytes; Diabetes Complications; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Mice; Oxidative Stress; Ribonucleotides

2021
PCB118 Induces Inflammation of Islet Beta Cells via Activating ROS-NLRP3 Inflammasome Signaling.
    BioMed research international, 2021, Volume: 2021

    Topics: Acetylcysteine; Animals; Caspase 1; Cell Survival; Cytokines; Diabetes Mellitus; Inflammasomes; Inflammation; Interleukin-1beta; Islets of Langerhans; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Signal Transduction

2021
Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Acetylcysteine; Animals; Blotting, Western; Cells, Cultured; Diabetes Mellitus; Free Radical Scavengers; Gastric Mucosa; Gene Expression; Glucose; Hyperglycemia; Mice, Inbred C57BL; Mice, Obese; MicroRNAs; Muscle Contraction; Muscle, Smooth; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Stomach; Up-Regulation

2017
Monocyte-Derived Procoagulant Microvesicles Induced by High Glucose Can Be Attenuated by the Antioxidant N-Acetyl-L-Cysteine, Partly Through the P38/MAPK Pathway.
    Metabolic syndrome and related disorders, 2017, Volume: 15, Issue:10

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Blood Coagulation; Cell Line; Cytoplasmic Vesicles; Diabetes Mellitus; Glucose; Humans; MAP Kinase Signaling System; Monocytes; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species

2017
Liver injury correlates with biomarkers of autoimmunity and disease activity and represents an organ system involvement in patients with systemic lupus erythematosus.
    Clinical immunology (Orlando, Fla.), 2015, Volume: 160, Issue:2

    Topics: Acetylcysteine; Adult; Alanine Transaminase; Antibodies, Antinuclear; Aspartate Aminotransferases; Azathioprine; Biomarkers; Cohort Studies; Complement System Proteins; Cyclosporine; Diabetes Mellitus; Female; Free Radical Scavengers; Humans; Immunosuppressive Agents; Liver Diseases; Longitudinal Studies; Lupus Erythematosus, Systemic; Male; Middle Aged; Mycophenolic Acid; Prednisone; Prevalence; Retrospective Studies; Severity of Illness Index; Sex Distribution; Sirolimus

2015
Glibenclamide impairs responses of neutrophils against Burkholderia pseudomallei by reduction of intracellular glutathione.
    Scientific reports, 2016, 10-07, Volume: 6

    Topics: Acetylcysteine; Adult; Burkholderia pseudomallei; Case-Control Studies; Cell Movement; Cytokines; Diabetes Mellitus; Female; Glutathione; Glyburide; Host-Pathogen Interactions; Humans; Hypoglycemic Agents; Male; Melioidosis; Neutrophils; Phagocytosis

2016
Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase.
    Diabetes, 2008, Volume: 57, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus; Diabetes Mellitus, Type 1; DNA Damage; DNA Glycosylases; Glucose; Hydrogen Peroxide; Immunoblotting; Immunohistochemistry; Kidney; Mice; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Rats; Reactive Oxygen Species; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2008
Aberrant production of extracellular matrix proteins and dysfunction in kidney endothelial cells with a short duration of diabetes.
    American journal of physiology. Renal physiology, 2013, Jan-01, Volume: 304, Issue:1

    Topics: Acetylcysteine; Animals; Cell Adhesion; Cell Movement; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Endothelial Cells; Extracellular Matrix Proteins; Fibronectins; Kidney; Kidney Failure, Chronic; Male; Mice; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Osteopontin; Vascular Endothelial Growth Factor A

2013
Effect of high-glucose levels on protein oxidation in cultured lens cells, and in crystalline and albumin solution and its inhibition by vitamin B6 and N-acetylcysteine: its possible relevance to cataract formation in diabetes.
    Free radical biology & medicine, 2002, Dec-15, Volume: 33, Issue:12

    Topics: Acetylcysteine; Albumins; Animals; Cataract; Cells, Cultured; Diabetes Complications; Diabetes Mellitus; Dose-Response Relationship, Drug; Glucose; Lens, Crystalline; Nephelometry and Turbidimetry; Oxidants; Oxidation-Reduction; Proteins; Rabbits; Vitamin B 6

2002
Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:1

    Topics: Acetylcysteine; Animals; Apolipoproteins B; Cells, Cultured; Cysteine Endopeptidases; Diabetes Mellitus; Disease Models, Animal; Gerbillinae; Hepatocytes; Hypercholesterolemia; Hyperinsulinism; Hypertriglyceridemia; Insulin; Insulin Resistance; Leupeptins; Lipoproteins, VLDL; Liver; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex

2004
The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glycoprotein embedded in the endoplasmic reticulum membrane.
    FEBS letters, 2004, Mar-26, Volume: 562, Issue:1-3

    Topics: Acetylcysteine; Amino Acid Sequence; Animals; Calreticulin; COS Cells; Cysteine Endopeptidases; Diabetes Mellitus; Endoplasmic Reticulum; Enzyme Inhibitors; Glucose-6-Phosphatase; Glycoproteins; Humans; Membrane Proteins; Mice; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Structure, Secondary; Proteins; Recombinant Fusion Proteins

2004
Five cysteine-containing compounds delay diabetic deterioration in Balb/cA mice.
    The Journal of nutrition, 2004, Volume: 134, Issue:12

    Topics: Acetylcysteine; Animals; Blood Glucose; Body Weight; Catalase; Cysteine; Diabetes Mellitus; Glutathione; Glutathione Peroxidase; Kidney; Liver; Male; Mice; Mice, Inbred BALB C

2004
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling.
    Genes to cells : devoted to molecular & cellular mechanisms, 2007, Volume: 12, Issue:8

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Cell Line; Checkpoint Kinase 1; Checkpoint Kinase 2; Deoxyguanosine; Diabetes Mellitus; Enzyme Activation; G2 Phase; Guanidines; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Kinase Kinase 5; Mesangial Cells; Mitosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Pyruvaldehyde; RNA, Small Interfering; Signal Transduction

2007
Suppression of phosphoenolpyruvate carboxykinase gene expression by reduced endogenous glutathione level.
    Biochimica et biophysica acta, 2007, Volume: 1772, Issue:10

    Topics: Acetylcysteine; Aging; Animals; Cell Line, Tumor; Diabetes Mellitus; Dithiothreitol; Energy Metabolism; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glutathione; Hepatocytes; Homeostasis; Male; Obesity; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphoenolpyruvate Carboxykinase (ATP); Rats; Rats, Sprague-Dawley; RNA, Messenger

2007
Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men.
    Diabetologia, 2008, Volume: 51, Issue:1

    Topics: Acetylcysteine; Administration, Oral; Adult; Diabetes Mellitus; Fatty Acids, Nonesterified; Free Radical Scavengers; Humans; Insulin; Insulin-Secreting Cells; Lipids; Male; Middle Aged; Obesity; Overweight; Taurine

2008
Oxidative stress and cystic fibrosis-related diabetes: a pilot study in children.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2008, Volume: 7, Issue:5

    Topics: Acetylcysteine; Adolescent; Analysis of Variance; Child; Cystic Fibrosis; Diabetes Mellitus; Fatty Acids; Female; Glucose Intolerance; Glucose Tolerance Test; Glutathione; Humans; Male; Membrane Proteins; Oxidative Stress; Pilot Projects; Respiratory Function Tests

2008