acetylcysteine has been researched along with Colorectal Cancer in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (9.09) | 18.2507 |
| 2000's | 13 (29.55) | 29.6817 |
| 2010's | 20 (45.45) | 24.3611 |
| 2020's | 7 (15.91) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, L; Chen, Q; Han, J; He, L; Huang, L; Li, B; Liu, H; Liu, X; Ma, K | 1 |
| Ahn, IH; Choi, IY; Choi, JR; Hwang, SG; Kang, AR; Kim, J; Kwon, JH; Lee, NG; Park, JK; Song, JY; Um, HD | 1 |
| Aimvijarn, P; Naktubtim, C; Suwannalert, P; Tanomrat, R | 1 |
| Allahyari, A; Barri, A; Bondad, N; Boostani, R; Elyasi, S | 1 |
| Liu, H; Lu, X; Shi, Z; Zhang, P; Zhao, S; Zhu, B | 1 |
| Chang, MC; Feng, CP; Guo, M; Hou, XX; Li, ZY; Liu, JY; Shi, JY | 1 |
| Kim, S; Kim, SH; Lee, CE | 1 |
| Hu, H; Huang, Z | 1 |
| Ahn, YR; Chung, HY; Hossain, MA; Hwang, NL; Hwang, SY; Jang, JY; Kang, YJ; Kim, DH; Kim, ND; Kim, SJ; Moon, HR; Oh, HJ; Sung, B; Ullah, S | 1 |
| Chen, J; He, L; Huang, L; Iwamoto, A; Lan, W; Lin, M; Liu, H; Lou, Q; Wang, F; Wen, C; Yang, X; Zhu, Z | 1 |
| Chen, YC; Lien, GS; Shen, SC; Wu, MS; Yang, LY | 1 |
| Attaix, D; Audebert, M; Cano, N; Corpet, DE; Dupuy, J; Guéraud, F; Kuhnle, GC; Martin, OC; Meunier, N; Mirvish, SS; Naud, N; Pierre, FH; Santarelli, RL; Taché, S; Vendeuvre, JL | 1 |
| Bagia, S; Quinn, L | 1 |
| Ito, F; Kanta, H; Khoi, NM; Ohta, S; Shiota, S; Takeuchi, K; Thuong, PT | 1 |
| Liu, Q; Niu, J; Wang, P; Wang, X; Wang, Y; Yan, H | 1 |
| Huseby, NE; Moens, U; Ravuri, C | 1 |
| Liu, X; Ren, G; Tian, K; Wang, Y; Xu, G; Xu, X; Xu, Z; Zhou, W | 1 |
| Guo, P; Liang, W; Liu, X; Wang, H; Wang, S; Wang, W; Zhao, M | 1 |
| Baek, SJ; Eling, TE; Hara, Y; Lee, SH; McEntee, MF; Sukhthankar, M; Yamaguchi, K | 1 |
| Cheng, WH; Lartey, FM; Qi, Y; Schoene, NW | 1 |
| Du, W; He, TC; Li, B; Searle, J; Wang, CZ; Yuan, CS; Zhao, J | 1 |
| Arbab-Ali, S; Deeb, D; Dulchavsky, SA; Gao, X; Gautam, SC; Liu, P; Liu, Y | 1 |
| Abdul-Razzak, KK; Aldaher, AN; Alkofahi, AS; Alsarhan, AM; Mhaidat, NM; Thorne, RF | 1 |
| Ahn, JS; Chung, JK; Erikson, RL; Jang, JH; Jeong, SJ; Kim, BY; Kwon, O; Kwon, YT; Lee, KS; Moon, DO; Soung, NK; Thimmegowda, NR | 1 |
| Al-Mulla, F; Bitar, MS; Feng, J; Park, S; Yeung, KC | 1 |
| Gao, FH; Guo, ZY; Jiang, B; Li, W; Liu, F; Liu, LB; Wei, W; Wu, YL; Xu, MH | 1 |
| Chen, C; Gong, K; Li, W; Wang, H; Zhan, Y | 1 |
| Aggarwal, BB; Prasad, S; Ravindran, J; Sung, B; Yadav, VR | 1 |
| Kelly, RG; Nally, K; O'Connell, J; Shanahan, F | 1 |
| Han, ST; Jin, IN; Kim, OH; Kim, YH; Kwon, TK; Lim, JH; Park, JW; Woo, KJ | 1 |
| Ong, CN; Shen, HM; Zhang, S | 1 |
| Borchert, GL; Donald, SP; Hu, CA; Liu, Y; Oberley, LW; Phang, JM; Surazynski, A; Weydert, CJ | 1 |
| Jakupec, MA; Kapitza, S; Keppler, BK; Marian, B; Uhl, M | 1 |
| Chao, TC; Chen, PM; Chiou, TJ; Hsiao, LT; Lee, MY; Lin, KP; Lin, PC; Wang, WS; Yang, MH; Yen, CC | 1 |
| Dorie, MJ; Freiberg, RA; Giaccia, AJ; Hammond, EM; Welford, SM | 1 |
| Kim, M; Murakami, A; Ohigashi, H | 1 |
| Corpet, DE; Guéraud, F; Pierre, F; Santarelli, R; Taché, S | 1 |
| Ponz de Leon, M; Roncucci, L | 1 |
| Beauchamp, RD; Brockman, JA; Chinery, R; Coffey, RJ; Peeler, MO; Shyr, Y | 1 |
| Boulares, H; Giardina, C; Inan, MS | 1 |
| Blomquist, JA; Estensen, RD; Galbraith, AR; Klopp, SJ; Levy, M; Mandel, JS; Wattenberg, LW | 1 |
| Chen, YC; Lee, WR; Lin, JK; Shen, SC; Tsai, SH | 1 |
| Albanese, C; D'Amico, M; Hawcroft, G; Hull, MA; Markham, AF; Pestell, RG | 1 |
| Ho, KL; Liao, J; Seril, DN; Yang, CS; Yang, GY | 1 |
5 trial(s) available for acetylcysteine and Colorectal Cancer
| Article | Year |
|---|---|
Protective effect of N-acetylcysteine on oxaliplatin-induced neurotoxicity in patients with colorectal and gastric cancers: A randomized, double blind, placebo-controlled, clinical trial.
Topics: Acetylcysteine; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colorectal Neoplasms; Double-Blind Method; Female; Humans; Male; Middle Aged; Neurotoxicity Syndromes; Oxaliplatin; Oxaloacetates; Stomach Neoplasms | 2020 |
Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers.
Topics: Abietanes; Acetylcysteine; Adult; Aged; alpha-Tocopherol; Animals; Biomarkers; Blood Glucose; C-Reactive Protein; Calcium, Dietary; Carcinogenesis; Carcinogens; Cholesterol; Colon; Colorectal Neoplasms; Creatinine; Cross-Over Studies; Dimethylhydrazines; Diphosphates; Feces; Female; Healthy Volunteers; Humans; Inulin; Meat Products; Middle Aged; Rats; Rats, Inbred F344; Rutin; Single-Blind Method; Thiobarbituric Acid Reactive Substances | 2013 |
N-acetylcysteine has neuroprotective effects against oxaliplatin-based adjuvant chemotherapy in colon cancer patients: preliminary data.
Topics: Acetylcysteine; Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Colorectal Neoplasms; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Neuroprotective Agents; Organoplatinum Compounds; Oxaliplatin; Pilot Projects; Postoperative Care | 2006 |
Chemoprevention of colorectal tumors: role of lactulose and of other agents.
Topics: Acetylcysteine; Adenomatous Polyps; Ascorbic Acid; Chemoprevention; Colorectal Neoplasms; Gastrointestinal Agents; Humans; Lactulose; Neoplasm Recurrence, Local; Vitamin A; Vitamin E | 1997 |
N-acetylcysteine suppression of the proliferative index in the colon of patients with previous adenomatous colonic polyps.
Topics: Acetylcysteine; Adenomatous Polyps; Administration, Oral; Age Factors; Biopsy; Chemoprevention; Cohort Studies; Colonic Polyps; Colorectal Neoplasms; Diet; Free Radical Scavengers; Humans; Intestinal Mucosa; Mitotic Index; Proliferating Cell Nuclear Antigen; Sex Factors | 1999 |
39 other study(ies) available for acetylcysteine and Colorectal Cancer
| Article | Year |
|---|---|
Identification of a new cyathane diterpene that induces mitochondrial and autophagy-dependent apoptosis and shows a potent in vivo anti-colorectal cancer activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Diterpenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Tumor Cells, Cultured | 2016 |
JNC-1043, a Novel Podophyllotoxin Derivative, Exerts Anticancer Drug and Radiosensitizer Effects in Colorectal Cancer Cells.
Topics: Acetylcysteine; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Humans; Podophyllotoxin; Propidium; Radiation-Sensitizing Agents; Reactive Oxygen Species | 2022 |
N-acetylcysteine improves the inhibitory effect of Quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion through iNOS suppression.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Glutathione; Humans; Intercellular Adhesion Molecule-1; Matrix Metalloproteinase 2; Onions; Quercetin | 2023 |
Metformin enhances the sensitivity of colorectal cancer cells to cisplatin through ROS-mediated PI3K/Akt signaling pathway.
Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cisplatin; Colorectal Neoplasms; Drug Resistance, Neoplasm; HCT116 Cells; Humans; Metformin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2020 |
Fruiting body polysaccharides of Hericium erinaceus induce apoptosis in human colorectal cancer cells via ROS generation mediating caspase-9-dependent signaling pathways.
Topics: Acetylcysteine; Agaricales; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; HCT116 Cells; Hericium; Humans; Membrane Potential, Mitochondrial; Polysaccharides; Reactive Oxygen Species; Signal Transduction | 2020 |
SOCS1 Represses Fractionated Ionizing Radiation-Induced EMT Signaling Pathways through the Counter-Regulation of ROS-Scavenging and ROS-Generating Systems.
Topics: Acetylcysteine; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Humans; Radiation, Ionizing; Reactive Oxygen Species; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Tumor Cells, Cultured | 2020 |
Arginine Deiminase Induces Immunogenic Cell Death and Is Enhanced by
Topics: Acetylcysteine; Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Colorectal Neoplasms; Humans; Hydrolases; Immunogenic Cell Death; Mice; Polyethylene Glycols | 2021 |
MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin B1; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species | 2017 |
Reduced-gliotoxin induces ROS-mediated anoikis in human colorectal cancer cells.
Topics: Acetylcysteine; Anoikis; Antineoplastic Agents; Colorectal Neoplasms; Gliotoxin; HCT116 Cells; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Signal Transduction | 2018 |
N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells.
Topics: Acetylcysteine; Apoptosis; Blotting, Western; Caspases; Cell Proliferation; Colorectal Neoplasms; Drug Synergism; Flavonoids; Flavonols; Free Radical Scavengers; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Reactive Oxygen Species; Tumor Cells, Cultured | 2014 |
Effective palliation of obstructive jaundice due to colorectal cancer liver metastasis.
Topics: Acetylcysteine; Aged, 80 and over; Colectomy; Colorectal Neoplasms; Drainage; Female; Follow-Up Studies; Humans; Jaundice, Obstructive; Liver Neoplasms; Monitoring, Physiologic; Palliative Care; Risk Assessment; Stents; Tomography, X-Ray Computed | 2014 |
ent-kaurane diterpenoids from Croton tonkinensis induce apoptosis in colorectal cancer cells through the phosphorylation of JNK mediated by reactive oxygen species and dual-specificity JNK kinase MKK4.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Croton; Diterpenes, Kaurane; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Structure-Activity Relationship | 2014 |
Anti-cancer effect and the underlying mechanisms of gypenosides on human colorectal cancer SW-480 cells.
Topics: Acetylcysteine; Actin Cytoskeleton; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Nucleus; Cell Shape; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Drug Screening Assays, Antitumor; Flow Cytometry; Gynostemma; Humans; Membrane Potential, Mitochondrial; Plant Extracts; Reactive Oxygen Species | 2014 |
The proteasome inhibitor lactacystin enhances GSH synthesis capacity by increased expression of antioxidant components in an Nrf2-independent, but p38 MAPK-dependent manner in rat colorectal carcinoma cells.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line, Tumor; Colorectal Neoplasms; Cysteine; Gene Expression Regulation, Neoplastic; Glutathione; Humans; MAP Kinase Signaling System; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proteasome Inhibitors; Rats | 2016 |
Oxidative stress induced autophagy in cancer associated fibroblast enhances proliferation and metabolism of colorectal cancer cells.
Topics: Acetylcysteine; Adenine; Autophagy; Blotting, Western; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coculture Techniques; Colorectal Neoplasms; Humans; Oxidative Stress | 2017 |
Salvianolic acid B reverses multidrug resistance in HCT‑8/VCR human colorectal cancer cells by increasing ROS levels.
Topics: Acetylcysteine; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; Benzofurans; Cell Line, Tumor; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Humans; Hydrogen Peroxide; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species | 2017 |
A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
Topics: Acetylcysteine; Adenomatous Polyposis Coli; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Time Factors; Transfection | 2008 |
Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Anticarcinogenic Agents; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Colorectal Neoplasms; Cysteine; DNA Breaks; DNA Mismatch Repair; DNA Repair Enzymes; DNA-Binding Proteins; Drug Resistance, Neoplasm; Guanosine; Humans; Mismatch Repair Endonuclease PMS2; Morpholines; MutL Protein Homolog 1; Nuclear Proteins; Organoselenium Compounds; Piperidines; Protein Serine-Threonine Kinases; Pyrones; Reactive Oxygen Species; Selenocysteine; Sodium Selenite; Tumor Suppressor Proteins | 2010 |
Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase Inhibitors; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Free Radical Scavengers; Ginsenosides; HCT116 Cells; HEK293 Cells; Humans; Mutation; NF-kappa B; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53; Vacuoles | 2011 |
Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Free Radicals; Humans; Oleanolic Acid; Reactive Oxygen Species | 2011 |
Altholactone induces apoptotic cell death in human colorectal cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase Inhibitors; Caspases, Initiator; Cell Death; Cell Survival; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Enzyme Activation; Fibroblasts; Furans; Goniothalamus; HCT116 Cells; HT29 Cells; Humans; Oxidative Stress; Propidium; Pyrones; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2012 |
Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation.
Topics: Acetylcysteine; Activating Transcription Factor 3; Antioxidants; Apoptosis; Caco-2 Cells; Caspase 3; Cell Cycle Checkpoints; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Glutathione; HCT116 Cells; Humans; Mycotoxins; Patulin; Phosphorylation; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Receptor, IGF Type 1; Signal Transduction | 2012 |
A new model for raf kinase inhibitory protein induced chemotherapeutic resistance.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Antioxidants; Apoptosis; Blotting, Western; Cisplatin; Colorectal Neoplasms; Doxorubicin; Doxycycline; Drug Resistance, Neoplasm; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Hydrogen Peroxide; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Microscopy, Confocal; Models, Biological; NF-E2-Related Factor 2; Phosphatidylethanolamine Binding Protein; Protein Binding; Proteolysis; RNA Interference; Thioctic Acid | 2012 |
Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells.
Topics: Acetylcysteine; Annexin A5; Apoptosis; beta-Galactosidase; Cell Line, Tumor; Cellular Senescence; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Diterpenes, Kaurane; Down-Regulation; Glutathione; Humans; Hydrogen Peroxide; Neoplasm Proteins; Proto-Oncogene Proteins c-myc; Reactive Oxygen Species; Thioredoxin-Disulfide Reductase; Tumor Suppressor Protein p53; Up-Regulation | 2012 |
P38 MAP kinase functions as a switch in MS-275-induced reactive oxygen species-dependent autophagy and apoptosis in human colon cancer cells.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Autophagy-Related Protein 7; Benzamides; Cell Survival; Colorectal Neoplasms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; HCT116 Cells; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Reactive Oxygen Species; Tumor Burden; Ubiquitin-Activating Enzymes; Up-Regulation; Xenograft Model Antitumor Assays | 2012 |
Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Topics: Acetylcysteine; Apoptosis; Apoptosis Regulatory Proteins; Capsaicin; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Colorectal Neoplasms; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA Interference; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP; TRPV Cation Channels; Up-Regulation | 2012 |
Type I insulin-like growth factor receptor expression on colorectal adenocarcinoma cell lines is decreased in response to the chemopreventive agent N-acetyl-l-cysteine.
Topics: Acetylcysteine; Adenocarcinoma; Anticarcinogenic Agents; Cell Division; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Receptor, IGF Type 1; Tumor Cells, Cultured | 2002 |
Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors.
Topics: Acetylcysteine; Apoptosis; Butyrates; Caspases; Cell Division; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Therapy, Combination; G2 Phase; Humans; Leupeptins; Mitosis; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ubiquitins | 2004 |
Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Buthionine Sulfoximine; Calcium; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Humans; Oxidation-Reduction; Reactive Oxygen Species; Sesquiterpenes; Sulfhydryl Compounds | 2004 |
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.
Topics: Acetylcysteine; Apoptosis; Catalase; Cell Death; Cell Line, Tumor; Colorectal Neoplasms; Humans; Hydrogen Peroxide; Kinetics; Proline Oxidase; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase; Transfection; Tumor Suppressor Protein p53 | 2005 |
The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Collagen Type XI; Colorectal Neoplasms; DNA Damage; Dose-Response Relationship, Drug; Humans; Indazoles; Mitochondria; Organometallic Compounds; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Ruthenium Compounds | 2005 |
DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response.
Topics: Acetylcysteine; Apoptosis; Ataxia Telangiectasia; Carcinoma; cdc25 Phosphatases; Cell Hypoxia; Cell Survival; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Damage; Free Radical Scavengers; G2 Phase; Humans; Oxygen; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Threonine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2006 |
Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.
Topics: Acetylcysteine; Antioxidants; Catechin; Colorectal Neoplasms; Culture Media; Curcumin; Gallic Acid; Genes, Reporter; HT29 Cells; Humans; Hydrogen Peroxide; Isothiocyanates; Luciferases; Matrix Metalloproteinase 7; RNA, Messenger; Transcription Factor AP-1 | 2007 |
Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium.
Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Antioxidants; Body Weight; Calcium, Dietary; Cattle; Cell Transformation, Neoplastic; Colorectal Neoplasms; Diet; Eating; Feces; Female; Heme; Meat; Olive Oil; Plant Oils; Rats; Rats, Inbred F344; Thiobarbituric Acid Reactive Substances | 2008 |
Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; CCAAT-Enhancer-Binding Proteins; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Doxorubicin; Drug Interactions; Enzyme Inhibitors; Fluorouracil; Humans; Nuclear Proteins; Pyrrolidines; Thiocarbamates; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin E | 1997 |
NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antioxidants; Apoptosis; Butyrates; Colorectal Neoplasms; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Indomethacin; Membrane Glycoproteins; NF-kappa B; Reactive Oxygen Species; Salicylic Acid; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells.
Topics: Acetylcysteine; Arsenites; Blotting, Northern; Blotting, Western; Colorectal Neoplasms; Curcumin; Cyclooxygenase Inhibitors; Dimerization; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Indomethacin; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Topics: Acetylcysteine; beta Catenin; Blotting, Western; Colorectal Neoplasms; Cyclin D1; Cytoskeletal Proteins; Desmoplakins; DNA; Dose-Response Relationship, Drug; Down-Regulation; Electrophoretic Mobility Shift Assay; gamma Catenin; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Interleukin-2; Isoenzymes; Nitrobenzenes; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C beta; Proto-Oncogene Proteins c-myc; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sulfonamides; Trans-Activators; Transcription Factors; Tumor Cells, Cultured | 2002 |
Inhibition of chronic ulcerative colitis-associated colorectal adenocarcinoma development in a murine model by N-acetylcysteine.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antioxidants; Cell Division; Colitis, Ulcerative; Colorectal Neoplasms; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL | 2002 |