acetylcysteine has been researched along with Colonic Neoplasms in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.00) | 18.7374 |
| 1990's | 8 (16.00) | 18.2507 |
| 2000's | 16 (32.00) | 29.6817 |
| 2010's | 23 (46.00) | 24.3611 |
| 2020's | 2 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bae, SY; Hong, JY; Jung, C; Kang, SS; Lee, SK; Park, HJ | 1 |
| Gajda, T; Grzywa, R; Oleksyszyn, J; Psurski, M; Rudnicka, A; Wietrzyk, J; Winiarski, Ł | 1 |
| Jung, YD; Li, S; Nguyen, TT; Park, SY; Sah, DK; Ung, TT | 1 |
| Chen, H; Nie, S; Qi, W; Wang, J; Xie, M; Zhang, K; Zhou, X; Zhou, Y | 1 |
| Bossis, G; Boulanger, M; Hyun, JW; Kang, HK; Kang, KA; Kim, SB; Paolillo, R; Piao, MJ; Ryu, YS; Shilnikova, K; Yi, JM; Yoon, SY | 1 |
| Ansari, IA; Farooqui, A; Khan, F; Khan, I | 1 |
| Lee, S; Liu, Q; Wang, P | 1 |
| Shao, R; Shen, H; Shen, X; Wang, B; Xia, Y; Zhang, J; Zhang, T; Zheng, P; Zou, P | 1 |
| Amadio, B; Baldi, A; Condello, M; Delfine, S; Mastrodonato, F; Meschini, S; Occhionero, G; Pellegrini, E; Spugnini, EP; Vincenzi, B | 1 |
| Forte, E; Giardina, G; Giuffrè, A; Malagrinò, F; Masi, L; Paulini, G; Tomé, CS; Vicente, JB; Zuhra, K | 1 |
| Chenni, FZ; Corpet, DE; Guéraud, F; Hobbs, DA; Kunhle, GG; Naud, N; Pierre, FH; Taché, S | 1 |
| Berkelhammer, J; Hopkins, S; Loo, G; Murphy, A; Testa, K | 1 |
| Kim, DH; Lee, YM; Lim, BO; Lim, JH; Park, SR | 1 |
| Akyol, A; Besler, HT; Buyuktuncer, Z; Kuyumcu, A; Ozmen, MM | 1 |
| Liu, J; Luo, Y; Ni, Y; Qian, X; Tao, S; Zhao, R | 1 |
| Akasaka, T; Hayashi, Y; Hikita, H; Iijima, H; Inoue, M; Inoue, T; Kodama, T; Kondo, J; Maekawa, A; Shinzaki, S; Takehara, T; Tatsumi, T; Tomita, Y; Tsujii, M; Tsujii, Y; Watabe, K; Yoshii, S | 1 |
| Denda, T; Hirobe, C; Imai, M; Kikuchi, H; Ohyama, K; Toyoda, H | 1 |
| Ha, J; Hwang, JT; Kwon, DY; Lee, YK; Park, IJ; Park, OJ | 1 |
| Chatila, M; El-Najjar, N; Gali-Muhtasib, H; Gandesiri, M; Moukadem, H; Ocker, M; Schneider-Stock, R; Vuorela, H | 1 |
| Izutani, Y; Nakamura, Y; Sakai, T; Watanabe, H; Yasuda, S; Yogosawa, S | 1 |
| Che, CT; Cheung, FW; Li, C; Liu, BP; Liu, WK; Wang, L | 1 |
| Aggarwal, BB; Pandey, MK; Prasad, S; Ravindran, J; Sung, B | 1 |
| Bae, YS; Jeon, SM; Kim, KJ; Kwon, TK; Lee, SJ | 1 |
| Cai, DQ; Kim, DH; Kim, SK; Lee, KJ; Qi, XF; Shim, KY; Teng, YC; Yoon, YS | 1 |
| Bershteĭn, LM; Boiarkina, MP; Kovalenko, IG; Kovalevskiĭ, AIu; Poroshina, TE; Revskoĭ, SIu; Vasil'ev, DA | 1 |
| Adnan, H; Antenos, M; Kirby, GM | 1 |
| Chang, WY; Chung, HS; Hyun, JW; Kang, KA; Kim, AD; Kim, HS; Ryu, MJ; Suh, IS | 1 |
| Calviello, G; Di Nicuolo, F; Palozza, P; Piccioni, E; Pioli, C; Serini, S; Torsello, A; Ubaldi, V; Wolf, FI | 1 |
| Choi, HJ; Huh, GY; Jeong, JH; Kim, HH; Kim, JM; Lee, HS; Seo, SY; Yoo, YH | 1 |
| Wang, H; Xu, H; Yang, X; Zhang, Z | 1 |
| Aizawa, S; Asano, J; Hayakari, M; Kudo, T; Ookawa, K; Tsuchida, S | 1 |
| Hopkins, RG; Loo, G; Powolny, A; Takahashi, K | 1 |
| Bracci-Laudiero, L; Brunelli, R; Greco, G; Gustafsson, AC; Krasnowska, EK; Lundeberg, J; Lundeberg, T; Parasassi, T; Pittaluga, E; Romano, MC; Serafino, A | 1 |
| Delaney, AB; Douglas, L; Houghton, JA; Izeradjene, K; Tillman, DM | 1 |
| Doroshow, JH | 1 |
| Assi, K; Gómez-Muñoz, A; Moussavi, M; Salh, B | 1 |
| Bingham, SA; Corpet, DE; Cross, AJ; Gasc, N; Gottardi, G; Guéraud, F; Peiro, G; Pierre, F; Taché, S | 1 |
| Kelloff, G; Rao, CV; Reddy, BS; Rivenson, A | 1 |
| Busch, AE; Greger, R; Hug, MJ; Köttgen, M; Kunzelmann, K | 1 |
| Blagosklonny, MV; el-Deiry, WS; Omura, S; Wu, GS | 1 |
| Henning, SJ; Jacomino, M; Shukla, P | 1 |
| Ho, YS; Lee, HM; Lin, JK; Mou, TC; Wang, YJ | 1 |
| Cadenas, E; Qiu, XB | 1 |
| Eitel, K; Hermisson, M; Wagenknecht, B; Weller, M | 1 |
| Chang, D; Chen, F; Goh, M; Klibanov, SA; Ljungman, M | 1 |
| Adeyemo, D; Imtiaz, F; Lowdell, M; Toffa, S; Wickremasinghe, RG; Winslet, M | 1 |
| Carthy, CM; Granville, DJ; Hunt, DW; Jolois, O; Matroule, JY; Piette, J | 1 |
| Bebensee, S; Dwivedi, C; Erickson, AK; Gilkerson, KK; Guan, X; Hoffman, BN; McFarland, DC; Pellegrini, J | 1 |
| Khoury, MD; Pereira, MA | 1 |
| Roberfroid, M; Speder, A; Wilpart, M | 1 |
3 trial(s) available for acetylcysteine and Colonic Neoplasms
| Article | Year |
|---|---|
Improved oxidative status in major abdominal surgery patients after N-acetyl cystein supplementation.
Topics: Abdomen; Acetylcysteine; Aged; Antioxidants; Colonic Neoplasms; Female; Glutathione; Humans; Male; Malondialdehyde; Middle Aged; Nitrates; Oxidative Stress; Pancreatic Neoplasms; Preoperative Care; Reactive Oxygen Species; Rectal Neoplasms; Stomach Neoplasms | 2015 |
[Influence of metformin and N-acetylcysteine on hormonal and genotoxic effects of estrogens and glucose in convalescent cancer patients].
Topics: Acetylcysteine; Aged; Blood Glucose; Body Mass Index; Breast Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Endometrial Neoplasms; Estrogens; Female; Free Radical Scavengers; Glucose; Humans; Hypoglycemic Agents; Interleukin-6; Metformin; Middle Aged; Neoplasms; Postmenopause; Treatment Outcome; Tumor Necrosis Factor-alpha | 2010 |
New marker of colon cancer risk associated with heme intake: 1,4-dihydroxynonane mercapturic acid.
Topics: Acetylcysteine; Adult; Aged; Animal Feed; Animals; Biomarkers, Tumor; Colonic Neoplasms; Diet; Female; Heme; Humans; Iron; Male; Middle Aged; Oxidative Stress; Rats; Rats, Inbred F344; Risk | 2006 |
47 other study(ies) available for acetylcysteine and Colonic Neoplasms
| Article | Year |
|---|---|
Antitumor Activity of Americanin A Isolated from the Seeds of Phytolacca americana by Regulating the ATM/ATR Signaling Pathway and the Skp2-p27 Axis in Human Colon Cancer Cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; Checkpoint Kinase 1; Checkpoint Kinase 2; Colonic Neoplasms; Dioxins; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Structure; Phytolacca americana; Protein Kinases; Seeds; Signal Transduction; Tumor Suppressor Protein p53 | 2015 |
Synthesis and biological activity of diisothiocyanate-derived mercapturic acids.
Topics: Acetylcysteine; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Humans; Isothiocyanates | 2016 |
Cholic Acid Stimulates MMP-9 in Human Colon Cancer Cells via Activation of MAPK, AP-1, and NF-κB Activity.
Topics: Acetylcysteine; Cell Line, Tumor; Cholic Acid; Colonic Neoplasms; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; NADPH Oxidases; NF-kappa B; Onium Compounds; Reactive Oxygen Species; Signal Transduction; Transcription Factor AP-1 | 2020 |
Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway.
Topics: Acetylcysteine; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Autophagy; Cell Death; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dendrobium; Membrane Potential, Mitochondrial; Mice; Mitochondria; Polysaccharides; Reactive Oxygen Species; Signal Transduction; TOR Serine-Threonine Kinases | 2021 |
DUOX2-mediated production of reactive oxygen species induces epithelial mesenchymal transition in 5-fluorouracil resistant human colon cancer cells.
Topics: Acetylcysteine; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Dual Oxidases; Epithelial-Mesenchymal Transition; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Mixed Function Oxygenases; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reactive Oxygen Species | 2018 |
Andrographolide Exhibits Anticancer Potential Against Human Colon Cancer Cells by Inducing Cell Cycle Arrest and Programmed Cell Death via Augmentation of Intracellular Reactive Oxygen Species Level.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Cycle Checkpoints; Cell Line; Colonic Neoplasms; Diterpenes; Epithelial Cells; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Oligopeptides; Reactive Oxygen Species; Tumor Stem Cell Assay | 2018 |
Diabetes-associated oxidative damage to DNA base in colon cells.
Topics: Acetylcysteine; Animals; Colon; Colonic Neoplasms; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; DNA Damage; DNA Glycosylases; Glucose; Guanine; HCT116 Cells; HT29 Cells; Humans; Mice; Oxidative Stress | 2019 |
Curcuminoid WZ26, a TrxR1 inhibitor, effectively inhibits colon cancer cell growth and enhances cisplatin-induced cell death through the induction of ROS.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Death; Cell Proliferation; Cell Survival; Cisplatin; Colonic Neoplasms; Curcumin; DNA Damage; Drug Synergism; HCT116 Cells; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Piperazines; Reactive Oxygen Species; Surface Plasmon Resonance; Thioredoxin Reductase 1; Xenograft Model Antitumor Assays | 2019 |
Anticancer activity of "Trigno M", extract of Prunus spinosa drupes, against in vitro 3D and in vivo colon cancer models.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Colonic Neoplasms; Female; Fluorouracil; HCT116 Cells; Humans; Mice, SCID; Models, Biological; Plant Extracts; Prunus; Spheroids, Cellular; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2019 |
Topics: Acetylcysteine; Cell Line, Tumor; Colonic Neoplasms; Energy Metabolism; Free Radical Scavengers; Humans; Hydrogen Sulfide; Mitochondria; Oxidoreductases Acting on Sulfur Group Donors; Sulfurtransferases | 2019 |
Heme-induced biomarkers associated with red meat promotion of colon cancer are not modulated by the intake of nitrite.
Topics: Acetylcysteine; Animals; Biomarkers; Body Weight; Colonic Neoplasms; Disease Models, Animal; Drinking Water; Eating; Feces; Heme; Lipid Peroxidation; Male; Meat; Nitrites; Nitroso Compounds; Rats, Inbred F344; Saliva; Sodium Nitrite; Thiobarbituric Acid Reactive Substances | 2013 |
Impact of antioxidants on the ability of phenolic phytochemicals to kill HCT116 colon cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Catechin; Cell Line, Tumor; Colonic Neoplasms; Curcumin; DNA Damage; Drug Interactions; Gene Expression; HCT116 Cells; Heme Oxygenase-1; HT29 Cells; Humans; Iron Chelating Agents | 2014 |
Anticancer activity of hispidin via reactive oxygen species-mediated apoptosis in colon cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Flow Cytometry; Humans; Pyrones; Reactive Oxygen Species | 2014 |
Paraoxonase 2 modulates a proapoptotic function in LS174T cells in response to quorum sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
Topics: 4-Butyrolactone; Acetylcysteine; Apoptosis; Aryldialkylphosphatase; beta-Cyclodextrins; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Homoserine; Humans; Microscopy, Electron, Transmission; Mitochondria; Mucin-2; Quorum Sensing | 2016 |
p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth.
Topics: Acetylcysteine; Animals; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Mice; Mutation; Neovascularization, Pathologic; Reactive Oxygen Species; Tumor Microenvironment; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2016 |
Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; DNA Fragmentation; Flavonoids; Free Radical Scavengers; Fruit; Gene Expression; Heme Oxygenase-1; Humans; Luteolin; Phytotherapy; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Vitex | 2009 |
Green tea catechin controls apoptosis in colon cancer cells by attenuation of H2O2-stimulated COX-2 expression via the AMPK signaling pathway at low-dose H2O2.
Topics: Acetylcysteine; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Apoptosis; Blotting, Western; Catechin; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Free Radical Scavengers; HT29 Cells; Humans; Hydrogen Peroxide; Oxidants; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Ribonucleotides; Signal Transduction; Tea; Tumor Suppressor Protein p53 | 2009 |
Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Oxidative Stress; Reactive Oxygen Species | 2010 |
Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells.
Topics: Acetylcysteine; Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; G2 Phase; Humans; Phosphorylation; Reactive Oxygen Species; STAT3 Transcription Factor; Triterpenes | 2010 |
Geoditin A induces oxidative stress and apoptosis on human colon HT29 cells.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Colonic Neoplasms; DNA Fragmentation; Dose-Response Relationship, Drug; Down-Regulation; Endocytosis; Free Radical Scavengers; Golgi Apparatus; HT29 Cells; Humans; Inhibitory Concentration 50; Iron Chelating Agents; Marine Toxins; Oxidants; Oxidative Stress; Receptors, Transferrin; Resorcinols; Triterpenes | 2010 |
Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.
Topics: Acetylcysteine; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Colonic Neoplasms; Down-Regulation; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Gene Knockdown Techniques; Humans; Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Receptors, Death Domain; Terpenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Up-Regulation | 2010 |
NADPH oxidase is involved in protein kinase CKII down-regulation-mediated senescence through elevation of the level of reactive oxygen species in human colon cancer cells.
Topics: Acetophenones; Acetylcysteine; Aging; Antioxidants; Casein Kinase II; Cellular Senescence; Colonic Neoplasms; Down-Regulation; Genes, p53; HCT116 Cells; Humans; Hydrogen Peroxide; Mitochondria; NADPH Oxidases; Reactive Oxygen Species; RNA, Small Interfering; Superoxides | 2010 |
Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells.
Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Colonic Neoplasms; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Oligopeptides; Oxidative Stress; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Simvastatin | 2010 |
The effect of menadione on glutathione S-transferase A1 (GSTA1): c-Jun N-terminal kinase (JNK) complex dissociation in human colonic adenocarcinoma Caco-2 cells.
Topics: Acetylcysteine; Adenocarcinoma; Aldehydes; Antifibrinolytic Agents; Caco-2 Cells; Colonic Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Enzymologic; Glutathione; Glutathione Transferase; Humans; Lipid Peroxidation; Malondialdehyde; MAP Kinase Kinase 4; Oxidative Stress; Time Factors; Vitamin K 3 | 2012 |
The green algae Ulva fasciata Delile extract induces apoptotic cell death in human colon cancer cells.
Topics: Acetylcysteine; Apoptosis; Colonic Neoplasms; DNA Fragmentation; HCT116 Cells; Humans; Mitochondrial Membranes; Plant Extracts; Reactive Oxygen Species; Ulva | 2013 |
Beta-carotene regulates NF-kappaB DNA-binding activity by a redox mechanism in human leukemia and colon adenocarcinoma cells.
Topics: Acetylcysteine; Adenocarcinoma; Apoptosis; beta Carotene; Colonic Neoplasms; Genes, myc; HL-60 Cells; Humans; NF-kappa B; Oxidation-Reduction; Reactive Oxygen Species | 2003 |
Lactacystin augments the sulindac-induced apoptosis in HT-29 cells.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma; Cell Line, Tumor; Colonic Neoplasms; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Synergism; HT29 Cells; Humans; Multienzyme Complexes; Proteasome Endopeptidase Complex; Reaction Time; Sulindac | 2003 |
Both calcium and ROS as common signals mediate Na(2)SeO(3)-induced apoptosis in SW480 human colonic carcinoma cells.
Topics: Acetylcysteine; Aniline Compounds; Apoptosis; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Catalase; Cell Line, Tumor; Cell Size; Cell Survival; Cobalt; Colonic Neoplasms; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Egtazic Acid; Flow Cytometry; Fluoresceins; Glutathione; Humans; Membrane Potentials; Mitochondria; Reactive Oxygen Species; Ruthenium Red; Sodium Selenite; Xanthenes | 2003 |
Characterization of cell death induced by ethacrynic acid in a human colon cancer cell line DLD-1 and suppression by N-acetyl-L-cysteine.
Topics: Acetylcysteine; Antioxidants; Cell Death; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Ethacrynic Acid; Fluorescence; Glutathione; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Mitogen-Activated Protein Kinases | 2003 |
Induction of GADD gene expression by phenethylisothiocyanate in human colon adenocarcinoma cells.
Topics: Acetylcysteine; Adenocarcinoma; Anticarcinogenic Agents; Antigens, Differentiation; Apoptosis; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Size; Colonic Neoplasms; Dactinomycin; DNA Damage; GADD45 Proteins; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Protein Phosphatase 1; Proteins; RNA, Messenger; Transcription Factor CHOP; Transcription Factors; Transcriptional Activation; Tumor Suppressor Protein p53 | 2003 |
Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms.
Topics: Acetylcysteine; beta Catenin; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Cell Line, Tumor; Colonic Neoplasms; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Female; Humans; Keratinocytes; Ovarian Neoplasms; Phosphotransferases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; src-Family Kinases; Sulfhydryl Compounds; Thymidine; Trans-Activators | 2005 |
Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Respiration; Colonic Neoplasms; Cytochromes c; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Glycoproteins; Mitochondria; Mitochondrial Proteins; Oxidative Phosphorylation; Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Uncoupling Agents; X-Linked Inhibitor of Apoptosis Protein | 2005 |
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Edetic Acid; Humans; Hydrogen Peroxide; Leukocytes; Mice; Oxidation-Reduction; Pyridoxal Phosphate; Reactive Oxygen Species | 2006 |
Curcumin mediates ceramide generation via the de novo pathway in colon cancer cells.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Ceramides; Colonic Neoplasms; Curcumin; Enzyme Activation; Fatty Acids, Monounsaturated; Humans; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured | 2006 |
Chemoprevention of colon carcinogenesis by organosulfur compounds.
Topics: Acetylcysteine; Allyl Compounds; Anethole Trithione; Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Disulfides; Glucuronosyltransferase; Glutathione Transferase; Male; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Inbred F344; Taurine | 1993 |
N-Acetyl-L-cysteine and its derivatives activate a Cl- conductance in epithelial cells.
Topics: Acetylcysteine; Animals; Bronchi; Cells, Cultured; Chloride Channels; Colonic Neoplasms; Cystic Fibrosis; Electric Conductivity; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Oocytes; Respiratory System; Tumor Cells, Cultured; Xenopus | 1996 |
Proteasome-dependent regulation of p21WAF1/CIP1 expression.
Topics: Acetylcysteine; Cell Line; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Luciferases; Multienzyme Complexes; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Biosynthesis; Recombinant Proteins; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
Use of amphotropic retroviral vectors for gene transfer in human colon carcinoma cells.
Topics: 3T3 Cells; Acetylcysteine; Animals; Caco-2 Cells; Colonic Neoplasms; Culture Media; Gene Transfer Techniques; Genetic Vectors; HT29 Cells; Humans; Mice; Phenobarbital; Rats; Retroviridae; Transformation, Genetic; Tumor Cells, Cultured | 1997 |
Suppression of nitric oxide-induced apoptosis by N-acetyl-L-cysteine through modulation of glutathione, bcl-2, and bax protein levels.
Topics: Acetylcysteine; Apoptosis; bcl-2-Associated X Protein; Colonic Neoplasms; DNA Fragmentation; Genes, bcl-2; Glutathione; HT29 Cells; Humans; Nitric Oxide; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1997 |
The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells.
Topics: Acetylcysteine; Aziridines; Benzoquinones; Blotting, Northern; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dicumarol; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Pentetic Acid; Quinones; Reactive Oxygen Species; RNA, Messenger; Tumor Cells, Cultured | 1997 |
Proteasome inhibitors induce p53/p21-independent apoptosis in human glioma cells.
Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Glioma; Glycoproteins; Humans; Kinetics; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Serine Proteinase Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Role of p53 in cell cycle regulation and apoptosis following exposure to proteasome inhibitors.
Topics: Acetylcysteine; Apoptosis; Cell Nucleus; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Fibroblasts; G1 Phase; G2 Phase; Humans; Interphase; Mitosis; Multienzyme Complexes; Proteasome Endopeptidase Complex; Skin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Antioxidants enhance the susceptibility of colon carcinoma cells to 5-fluorouracil by augmenting the induction of the bax protein.
Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Colonic Neoplasms; Drug Interactions; Flow Cytometry; Fluorouracil; Free Radical Scavengers; Humans; Oxidation-Reduction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Time Factors; Tumor Cells, Cultured; Vitamin E | 2001 |
Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization.
Topics: Acetylcysteine; Adenocarcinoma; Antioxidants; Apoptosis; Caspase 3; Caspases; Ceramides; Chloroquine; Colonic Neoplasms; Cytochrome c Group; Deuterium Oxide; Endoplasmic Reticulum; Gene Expression Regulation, Neoplastic; Golgi Apparatus; Humans; Lysosomes; Mannans; Mannosephosphates; Microscopy, Fluorescence; Mitochondria; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Oxygen; Phosphorylation; Photochemistry; Photosensitizing Agents; Proline; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; Radiation-Protective Agents; Reactive Oxygen Species; Second Messenger Systems; Singlet Oxygen; Thiocarbamates; Tumor Cells, Cultured | 2001 |
Glutathione and mercapturic acid conjugates of sulofenur and their activity against a human colon cancer cell line.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Bile; Cell Division; Chromatography, High Pressure Liquid; Colonic Neoplasms; Cysteine; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Glutathione; Glutathione Reductase; Humans; Magnetic Resonance Spectroscopy; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Sulfonylurea Compounds; Tumor Cells, Cultured | 2002 |
Prevention by chemopreventive agents of azoxymethane-induced foci of aberrant crypts in rat colon.
Topics: Acetylcysteine; Allyl Compounds; Animals; Anticarcinogenic Agents; Azoxymethane; Colon; Colonic Neoplasms; Dehydroepiandrosterone; Eflornithine; Ellagic Acid; Isothiocyanates; Male; Precancerous Conditions; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Sulfides; Thiazoles; Thiazolidines; Thiocyanates | 1991 |
Anti-initiation activity of N-acetylcysteine in experimental colonic carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Intestinal Neoplasms; Male; Methylhydrazines; Rats; Rats, Inbred Strains | 1986 |