acetylcysteine has been researched along with Cocaine Abuse in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 19 (70.37) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Greenwald, MK; Khatib, D; Lundahl, LH; Stanley, JA; Woodcock, EA | 1 |
| Boendermaker, WJ; Goudriaan, AE; Schulte, MHJ; van den Brink, W; Wiers, RW | 1 |
| Alcorn, JL; Hays, LR; Levi Bolin, B; Lile, JA; Rayapati, AO; Rush, CR; Stoops, WW | 1 |
| Boendermaker, WJ; Brede, E; Friese, M; Goudriaan, AE; Schulte, MHJ; van den Brink, W; van Deursen, DS; Waters, AJ; Wiers, RW | 1 |
| Kalivas, PW; Townsend, DM; Uys, JD; Womersley, JS | 1 |
| Bergman, J; Doyle, RJ; Kangas, BD; Kaufman, MJ; Kohut, SJ | 1 |
| Boendermaker, WJ; Goudriaan, AE; Kaag, AM; Schulte, MHJ; van den Brink, W; Wiers, RW | 1 |
| Garcia-Keller, C; Gass, J; Kalivas, PW; Melton, S; Monforton, C; Smiley, C | 1 |
| Kalivas, P; Post, RM | 1 |
| Gasperino, J; Jacobs, D; Ladi, L; Plush, T; Sethi, S; Shakespeare, W | 1 |
| Gipson, CD; Kalivas, PW; Knackstedt, LA; Reissner, KJ; Scofield, MD; Tran, PK | 1 |
| Belin, D; Belin-Rauscent, A; Ducret, E; Dugast, E; Everitt, BJ; Fouyssac, M; Houeto, JL; Lacoste, J; Murray, JE; Puaud, M | 1 |
| Atlas, D; Filip, M; Frankowska, M; Jastrzębska, J | 1 |
| Bell, RL; Breier, A; Chambers, RA; Engleman, EA; Hulvershorn, LA; Rao, KN; Sentir, AM | 1 |
| Andrade Reis, T; da Silveira, DX; Fidalgo, TM; Nocito Echevarria, MA; Ruffo Capatti, G; Siciliano Soares, V | 1 |
| Gass, JT; Kalivas, PW; Lavin, A; Moran, M; Moussawi, K; Olive, MF; Pacchioni, A | 1 |
| Ahmad, ME; Amen, SL; Baker, DA; Li, SJ; Mantsch, JR; Piacentine, LB; Risinger, RC | 1 |
| Carr, DB; Kalivas, PW; Moussawi, K; Reichel, CM; See, RE; Shen, H; Zhou, W | 1 |
| Do, PH; Kalivas, PW; Moussawi, K; Reichel, CM; See, RE | 1 |
| Belin, D; Everitt, BJ; Murray, JE | 1 |
| Amore, M; Ciccocioppo, R; Donnini, C; Gerra, G; Gerra, ML; Kalluppi, M; Malagoli, M; Raggi, MA; Saracino, MA; Somaini, L | 1 |
| Goudriaan, AE; Nederveen, A; Schmaal, L; van den Brink, W; Veltman, DJ | 1 |
| Caflisch, C; Herdener, M; Oppliger, R; Stohler, R | 1 |
| Baker, DA; Kalivas, PW; Lake, RW; McFarland, K; Shen, H; Tang, XC; Toda, S | 1 |
| Baker, DA; Kalivas, PW; Lake, RW; McFarland, K; Shen, H; Toda, S | 1 |
| Hedden, S; Kalivas, PW; LaRowe, SD; Malcolm, RJ; Mardikian, PN | 1 |
| Brady, K; Hedden, S; Kalivas, PW; LaRowe, SD; Malcolm, R; Mardikian, P; McRae, A; Myrick, H; Saladin, M | 1 |
6 review(s) available for acetylcysteine and Cocaine Abuse
| Article | Year |
|---|---|
Targeting redox regulation to treat substance use disorder using N‐acetylcysteine
Topics: Acetylcysteine; Animals; Cocaine-Related Disorders; Drug Delivery Systems; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Substance-Related Disorders | 2019 |
Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation.
Topics: Acetylcysteine; Age of Onset; Animals; Basal Ganglia; Behavior, Addictive; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Cocaine; Cocaine-Related Disorders; Comorbidity; Diagnosis, Dual (Psychiatry); Disease Models, Animal; Disease Progression; Dopamine Uptake Inhibitors; Epigenomics; Free Radical Scavengers; Humans; Recurrence; Stress, Psychological | 2013 |
Cocaine-induced agitated delirium: a case report and review.
Topics: Acetylcysteine; Anti-Bacterial Agents; Cocaine-Related Disorders; Critical Care; Delirium; Early Diagnosis; Fever; Humans; Intubation, Intratracheal; Male; Middle Aged; Psychomotor Agitation; Treatment Outcome; Urinary Catheterization | 2015 |
N-acetylcysteine for treating cocaine addiction - A systematic review.
Topics: Acetylcysteine; Animals; Cocaine-Related Disorders; Female; Free Radical Scavengers; Glutamic Acid; Humans; Male; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recurrence; Secondary Prevention; Treatment Outcome | 2017 |
Promising medications for cocaine dependence treatment.
Topics: Acetylcysteine; Atomoxetine Hydrochloride; Baclofen; Benzhydryl Compounds; Buprenorphine; Cocaine-Related Disorders; Fructose; Humans; Modafinil; Ondansetron; Patents as Topic; Propylamines; Topiramate | 2011 |
[Treating cocaine addiction].
Topics: Acetylcysteine; Alcohol Deterrents; Baclofen; Benzhydryl Compounds; Central Nervous System Stimulants; Cocaine-Related Disorders; Cross-Sectional Studies; Diagnosis, Dual (Psychiatry); Disulfiram; Free Radical Scavengers; Humans; Mental Disorders; Methylphenidate; Modafinil; Muscle Relaxants, Central; Psychotherapy; Switzerland | 2012 |
7 trial(s) available for acetylcysteine and Cocaine Abuse
| Article | Year |
|---|---|
N-acetylcysteine reduces cocaine-seeking behavior and anterior cingulate glutamate/glutamine levels among cocaine-dependent individuals.
Topics: Acetylcysteine; Adult; Cocaine-Related Disorders; Cross-Over Studies; Double-Blind Method; Drug-Seeking Behavior; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Middle Aged; Proton Magnetic Resonance Spectroscopy; Reward | 2021 |
The effect of N-acetylcysteine and working memory training on glutamate concentrations in the dACC and rACC in regular cocaine users - A randomized proof of concept study.
Topics: Acetylcysteine; Adult; Cocaine-Related Disorders; Double-Blind Method; Glutamic Acid; Gyrus Cinguli; Humans; Learning; Male; Memory, Short-Term; Middle Aged; Proof of Concept Study | 2021 |
The effect of N-acetylcysteine and working memory training on cocaine use, craving and inhibition in regular cocaine users: correspondence of lab assessments and Ecological Momentary Assessment.
Topics: Acetylcysteine; Adult; Cocaine-Related Disorders; Craving; Ecological Momentary Assessment; Free Radical Scavengers; Humans; Inhibition, Psychological; Learning; Male; Memory, Short-Term; Middle Aged; Stroop Test | 2018 |
The effect of N-acetylcysteine and working memory training on neural mechanisms of working memory and cue reactivity in regular cocaine users.
Topics: Acetylcysteine; Brain; Cocaine; Cocaine-Related Disorders; Cognition; Cues; Double-Blind Method; Humans; Male; Memory, Short-Term | 2019 |
N-acetylcysteine normalizes glutamate levels in cocaine-dependent patients: a randomized crossover magnetic resonance spectroscopy study.
Topics: Acetylcysteine; Adult; Cocaine-Related Disorders; Cross-Over Studies; Glutamic Acid; Gyrus Cinguli; Humans; Magnetic Resonance Spectroscopy; Male; Pilot Projects | 2012 |
An open-label trial of N-acetylcysteine for the treatment of cocaine dependence: a pilot study.
Topics: Acetylcysteine; Adolescent; Adult; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Pilot Projects; Treatment Outcome | 2007 |
Is cocaine desire reduced by N-acetylcysteine?
Topics: Acetylcysteine; Adult; Affect; Behavior, Addictive; Cocaine-Related Disorders; Cross-Over Studies; Cues; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Placebos; Secondary Prevention; Visual Perception | 2007 |
14 other study(ies) available for acetylcysteine and Cocaine Abuse
| Article | Year |
|---|---|
N-Acetylcysteine reduces cocaine-cue attentional bias and differentially alters cocaine self-administration based on dosing order.
Topics: Acetylcysteine; Animals; Attentional Bias; Cocaine; Cocaine-Related Disorders; Cues; Double-Blind Method; Glutamic Acid; Humans; Motivation; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration | 2017 |
Effects of chronic cocaine self-administration and N-acetylcysteine on learning, cognitive flexibility, and reinstatement in nonhuman primates.
Topics: Acetylcysteine; Animals; Cocaine; Cocaine-Related Disorders; Cognition; Conditioning, Operant; Discrimination Learning; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Free Radical Scavengers; Male; Photic Stimulation; Primates; Reinforcement, Psychology; Saimiri; Self Administration | 2019 |
N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse.
Topics: Acetylcysteine; Acute Disease; Alcohol-Related Disorders; Animals; Cocaine; Cocaine-Related Disorders; Cues; Disease Models, Animal; Drug-Seeking Behavior; Ethanol; Free Radical Scavengers; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Stress, Psychological | 2020 |
Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement.
Topics: Acetylcysteine; Amino Acid Transport Systems, Acidic; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Excitatory Amino Acid Transporter 2; Free Radical Scavengers; Inhibition, Psychological; Rats; Reinforcement, Psychology; Self Administration | 2015 |
N-acetylcysteine Facilitates Self-Imposed Abstinence After Escalation of Cocaine Intake.
Topics: Acetylcysteine; Animals; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Early Growth Response Protein 1; Electroshock; Excitatory Amino Acid Transporter 2; Male; Nucleus Accumbens; Punishment; Rats; Reinforcement Schedule; Self Administration; Time Factors | 2016 |
N-acetylcysteine amide (AD4) reduces cocaine-induced reinstatement.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Cues; Depression; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Male; Olfactory Bulb; Rats; Rats, Wistar; Reward; Self Administration | 2016 |
Toward early estimation and treatment of addiction vulnerability: radial arm maze and N-acetyl cysteine before cocaine sensitization or nicotine self-administration in neonatal ventral hippocampal lesion rats.
Topics: Acetylcysteine; Animals; Animals, Newborn; Behavior, Addictive; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Disease Models, Animal; Drug-Seeking Behavior; Free Radical Scavengers; Hippocampus; Male; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2016 |
N-Acetylcysteine reverses cocaine-induced metaplasticity.
Topics: Acetylcysteine; Animals; Behavior, Animal; Cocaine-Related Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Free Radical Scavengers; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Neuronal Plasticity; Nucleus Accumbens; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Secondary Prevention; Self Administration; Substance Withdrawal Syndrome | 2009 |
Repeated N-acetyl cysteine reduces cocaine seeking in rodents and craving in cocaine-dependent humans.
Topics: Acetylcysteine; Adult; Animals; Behavior, Addictive; Cocaine-Related Disorders; Conditioning, Operant; Humans; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Species Specificity | 2011 |
Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse.
Topics: Acetylcysteine; Animals; Chromatography, High Pressure Liquid; Cocaine-Related Disorders; Glutamic Acid; Homeostasis; Long-Term Potentiation; Microdialysis; Nucleus Accumbens; Patch-Clamp Techniques; Prefrontal Cortex; Rats; Receptors, Metabotropic Glutamate; Secondary Prevention; Signal Transduction; Synaptic Transmission | 2011 |
Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking.
Topics: Acetylcysteine; Animals; Cocaine; Cocaine-Related Disorders; Cues; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Extinction, Psychological; Glutamic Acid; Homeostasis; Male; Rats; Rats, Sprague-Dawley; Recurrence; Self Administration; Substance Withdrawal Syndrome | 2011 |
N-Acetylcysteine reduces early- and late-stage cocaine seeking without affecting cocaine taking in rats.
Topics: Acetylcysteine; Animals; Cocaine; Cocaine-Related Disorders; Dose-Response Relationship, Drug; Drug-Seeking Behavior; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Administration | 2012 |
Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse.
Topics: Acetylcysteine; Adaptation, Physiological; Analysis of Variance; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Corpus Striatum; Cystine; Dose-Response Relationship, Drug; Expectorants; Extinction, Psychological; Extracellular Space; Glutamic Acid; Male; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Recurrence; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Time Factors | 2003 |
N-acetyl cysteine-induced blockade of cocaine-induced reinstatement.
Topics: Acetylcysteine; Animals; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Microdialysis; Rats; Secondary Prevention | 2003 |