acetylcysteine has been researched along with Chronic Lung Injury in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (10.81) | 18.2507 |
| 2000's | 6 (16.22) | 29.6817 |
| 2010's | 19 (51.35) | 24.3611 |
| 2020's | 8 (21.62) | 2.80 |
| Authors | Studies |
|---|---|
| Bai, Y; Chen, Q; Hu, S; Pan, Y; Shao, C; Song, Y; Zhang, J; Zhao, X; Zhu, L | 1 |
| Chi, MC; Guo, SE; Huang, TH; Hwang, SL; Lee, CW; Lin, CM; Shi, CS | 1 |
| Guan, Y; Li, G; Liu, N; Ma, Z; Wang, R; Yao, S; Zhao, L | 1 |
| Calkovska, A; Hanusrichterova, J; Kolomaznik, M; Kosutova, P; Mikolka, P; Mokra, D; Vatecha, M; Zila, I | 1 |
| Elfsmark, L; Gustafson, Å; Jonasson, S; Karlsson, T | 1 |
| Charbonney, E; Charles, WN; Cleland, H; Collins, D; Davies, R; Dunn, K; Gantner, D; Giles, J; Jeschke, M; Jones, I; Lee, N; Legrand, M; Leon-Villapalos, J; Lloyd, J; Martin-Loeches, I; Milton-Jones, H; Pantet, O; Samaan, M; Shelley, O; Singh, S; Sisson, A; Soussi, S; Spragg, K; Vizcaychipi, MP; Williams, A; Wood, F; Yarrow, J | 1 |
| Guo, DW; Shih, HC; Wang, CY | 1 |
| Eghtedardoost, M; Ghanei, M; Ghavami, S; Ghazanfari, T; Hassan, ZM; Sadeghipour, A | 1 |
| Lin, X; Song, F; Wang, Y; Wei, M; Xue, DI | 1 |
| Ku, HJ; Lee, JH; Park, JH; Park, JW | 1 |
| Chen, L; Guo, F; Huang, X; Qiao, J | 1 |
| Ba, J; Chen, S; Pan, H; Tao, Y; Wang, M | 1 |
| Ettinger, NA; Gupta, R | 1 |
| Chen, TH; Liao, FT; Wang, JC; Wang, JJ; Wu, NC; Yang, YC | 1 |
| Akpolat, M; Cerkezkayabekir, A; Karamustafaoglu, A; Sapmaz-Metin, M; Tarladacalisir, T; Topcu-Tarladacalisir, Y; Turan, FN; Uz, YH | 1 |
| Barbosa de Castro, CM; Dornelas de Andrade, AF; Filho, CA; Galvão, AM; Melo-Junior, MR; Silva, LA; Silva, RA; Souza Maia, MB; Streck, EL; Wanderley, MS | 1 |
| Andrade, CF; da Rosa, DP; Forgiarini, LA; Forgiarini, LF; Mariano, R; Paludo, Ade O; Silva, MB | 1 |
| Churchill, TA; Fortis, S; Khadaroo, RG; Salim, SY; Streutker, C; Zhang, H | 1 |
| Antosova, M; Calkovska, A; Drgova, A; Durdik, P; Mokra, D; Mokry, J | 1 |
| Chen, N; Isobe, K; Ito, S; Liu, L; Nishio, N; Sun, Y; Tanaka, Y | 1 |
| Adeeb, S; Ahlers, ST; Chavko, M; McCarron, RM | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S; Smith, M; Stone, WL | 1 |
| Jiang, HN; Qu, JM; Xu, JF; Xu, P; Zhang, HJ; Zhang, J | 1 |
| Kuang, FW; Tan, LP; Xu, F | 1 |
| Bezerra, FS; Machado, MN; Pires, KM; Porto, LC; Valença, SS; Zin, WA | 1 |
| Balazs, L; Bezawada, L; Ghosh, MC; Gorantla, VK; Luellen, C; Makena, PS; Parthasarathi, K; Sinclair, SE; Waters, CM | 1 |
| Castro Junior, MA; Castro, AP; Facin, E; Fagundes, DJ; Lauz, S; Simões, Mde J | 1 |
| Asl, AH; Jahanshahi, A; Khansari, M; Sotoudeh, A; Takhtfooladi, HA; Takhtfooladi, MA | 1 |
| Collía, F; De Dios, I; Manso, MA; Ramudo, L; Yubero, S | 1 |
| Ferreira, SG; Koike, MK; Montero, EF; Oliveira Filho, LD; Saad, KR; Saad, PF | 1 |
| Arantes-Costa, FM; Landucci, EC; Leme, AS; Lichtenstein, A; Martins, MA | 1 |
| Jin, X; Tian, Y; Wang, CY; Wu, HS; Zhang, JH | 1 |
| Domenighetti, G; Laverrière, MC; Perret, C; Ritz, R; Schaller, MD; Suter, PM | 1 |
| Benson, PF; Doctrow, SR; Fink, MP; Gonzalez, PK; Malfroy, B; Menconi, MJ; Zhuang, J | 1 |
| Davreux, CJ; McGilvray, ID; Nathens, AB; Rotstein, OD; Shek, PN; Soric, I; Suntres, ZE; Watson, RW | 1 |
| Brown, LA; Guidot, DM; Holguin, F; Moss, I | 1 |
| Bahler, AA; Barrios, R; Kala, G; Kala, SV; Lieberman, MW; Ou, CN; Shi, ZZ; Welty, SE; Wiseman, AL | 1 |
1 review(s) available for acetylcysteine and Chronic Lung Injury
| Article | Year |
|---|---|
Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury.
Topics: Acetylcysteine; Adult; Animals; Catalase; Disease Models, Animal; Endotoxins; Ethylenediamines; Free Radical Scavengers; Humans; Lipopolysaccharides; Lung; Lung Injury; Organometallic Compounds; Oxidative Stress; Reactive Oxygen Species; Respiratory Distress Syndrome; Superoxide Dismutase; Swine; Thiourea | 1996 |
1 trial(s) available for acetylcysteine and Chronic Lung Injury
| Article | Year |
|---|---|
N-acetylcysteine enhances recovery from acute lung injury in man. A randomized, double-blind, placebo-controlled clinical study.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Lung; Lung Injury; Male; Middle Aged; Oxygen Consumption; Oxygen Inhalation Therapy; Placebos; Respiration, Artificial; Respiratory Distress Syndrome; Risk Factors; Severity of Illness Index; Survival Rate; Time Factors; Treatment Outcome | 1994 |
35 other study(ies) available for acetylcysteine and Chronic Lung Injury
| Article | Year |
|---|---|
Fractionated Irradiation of Right Thorax Induces Abscopal Damage on Bone Marrow Cells via TNF-α and SAA.
Topics: Acetylcysteine; Animals; Blood Proteins; Bone Marrow Cells; Cell Cycle; DNA Damage; Dose Fractionation, Radiation; Free Radical Scavengers; Lung Injury; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Proteomics; Reactive Oxygen Species; Serum Amyloid A Protein; Thorax; Tumor Necrosis Factor-alpha | 2021 |
N-acetylcysteine alleviates fine particulate matter (PM2.5)-induced lung injury by attenuation of ROS-mediated recruitment of neutrophils and Ly6C
Topics: Acetylcysteine; Animals; Interleukin-6; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Monocytes; Neutrophils; Nitrites; Particulate Matter; Pneumonia; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2022 |
N-acetylcysteine alleviates pulmonary alveolar proteinosis induced by indium-tin oxide nanoparticles in male rats: involvement of the NF-κB signaling pathway.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Indium; Lung; Lung Injury; Male; Nanoparticles; NF-kappa B; Pulmonary Alveolar Proteinosis; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Signal Transduction; Tin Compounds; Tumor Necrosis Factor-alpha | 2022 |
Efficiency of exogenous surfactant combined with intravenous N-acetylcysteine in two-hit rodent model of ARDS.
Topics: Acetylcysteine; Animals; Antioxidants; Hyperoxia; Lung; Lung Injury; Pulmonary Surfactants; Rats; Rats, Wistar; Respiratory Distress Syndrome; Rodentia; Surface-Active Agents | 2023 |
N-acetyl cysteine mitigates lung damage and inflammation after chlorine exposure in vivo and ex vivo.
Topics: Acetylcysteine; Animals; Antioxidants; Chlorine; Inflammation; Inflammation Mediators; Lung; Lung Injury; Mice; Swine | 2023 |
An international RAND/UCLA expert panel to determine the optimal diagnosis and management of burn inhalation injury.
Topics: Acetylcysteine; Albuterol; Burns; Heparin; Humans; Lung Injury; Respiration, Artificial | 2023 |
N-acetylcysteine and atorvastatin alleviates lung injury due to ischemia-reperfusion injury in rats.
Topics: Acetylcysteine; Animals; Atorvastatin; Cytokines; Lung Injury; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2019 |
Delayed effects of sulfur mustard on autophagy suppression in chemically-injured lung tissue.
Topics: Acetylcysteine; Adult; Albuterol; Armed Conflicts; Autophagy; Beclin-1; Case-Control Studies; Chemical Warfare Agents; Down-Regulation; Female; Humans; Iran; Lung; Lung Injury; Male; Microtubule-Associated Proteins; Middle Aged; Military Personnel; Mustard Gas; Oxidative Stress; Time Factors | 2020 |
N-acetylcysteine (NAC) Attenuating Apoptosis and Autophagy in RAW264.7 Cells in Response to Incubation with Mycolic Acid from Bovine
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Gene Expression Regulation; Lung; Lung Injury; Mice; Mycobacterium tuberculosis; Mycolic Acids; RAW 264.7 Cells; TOR Serine-Threonine Kinases | 2020 |
Topics: Acetylcysteine; Acrolein; Animals; Carcinoma, Lewis Lung; Isocitrate Dehydrogenase; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NADP; Oxidation-Reduction; Oxidative Stress; RNA, Small Interfering | 2017 |
Effects of nebulized N--acetylcystein on the expression of HMGB1 and RAGE in rats with hyperoxia--induced lung injury.
Topics: Acetylcysteine; Animals; Animals, Newborn; Disease Models, Animal; Gene Expression Regulation; HMGB1 Protein; Humans; Hyperoxia; Lung; Lung Injury; Nebulizers and Vaporizers; NF-kappa B; Rats; Receptor for Advanced Glycation End Products; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Multiple mechanisms of N-acetylcysteine against formaldehyde-induced lung injury.
Topics: Acetylcysteine; Formaldehyde; Humans; Lung Injury; Models, Theoretical | 2013 |
Beyond conventional therapy: role of pulse steroids in bleomycin induced lung injury.
Topics: Acetylcysteine; Aged; Anti-Inflammatory Agents; Bleomycin; Female; Free Radical Scavengers; Humans; Lung Injury; Methylprednisolone; Oxygen Inhalation Therapy; Retreatment | 2014 |
N-acetylcysteine improves cardiac contractility and ameliorates myocardial injury in a rat model of lung ischemia and reperfusion injury.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Bronchoalveolar Lavage Fluid; Creatine Kinase, MB Form; Cytoprotection; Disease Models, Animal; Hydroxyl Radical; Lipid Peroxidation; Lung; Lung Injury; Male; Myocardial Contraction; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors; Troponin I; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure | 2013 |
N-Acetylcysteine counteracts oxidative stress and protects alveolar epithelial cells from lung contusion-induced apoptosis in rats with blunt chest trauma.
Topics: Acetylcysteine; Animals; Apoptosis; Contusions; Epithelial Cells; Female; Lung Injury; Oxidative Stress; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Thoracic Injuries | 2014 |
Intratracheal co-administration of antioxidants and ceftriaxone reduces pulmonary injury and mortality rate in an experimental model of sepsis.
Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Ceftriaxone; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Lung Injury; Male; Rats; Rats, Wistar; Sepsis; Trachea; Vitamin E | 2014 |
N-acetylcysteine administration confers lung protection in different phases of lung ischaemia-reperfusion injury.
Topics: Acetylcysteine; Administration, Intravenous; Animals; Anti-Inflammatory Agents; Antioxidants; Caspase 3; Cytoprotection; Disease Models, Animal; Hemodynamics; I-kappa B Kinase; Inflammation Mediators; Interleukin-1beta; Lipid Peroxidation; Lung; Lung Injury; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2014 |
I-FABP as biomarker for the early diagnosis of acute mesenteric ischemia and resultant lung injury.
Topics: Acetylcysteine; alpha-Defensins; Animals; Biomarkers; Disease Models, Animal; Early Diagnosis; Fatty Acid-Binding Proteins; Lung Injury; Male; Mesenteric Ischemia; Mice; Mice, Inbred C57BL | 2014 |
N-acetylcysteine effectively diminished meconium-induced oxidative stress in adult rabbits.
Topics: Acetylcysteine; Age Factors; Animals; Antioxidants; Biomarkers; Disease Models, Animal; Humans; Infant, Newborn; Inflammation Mediators; Leukocytes; Lipid Peroxidation; Lung; Lung Injury; Meconium; Meconium Aspiration Syndrome; Mitochondria; Oxidative Stress; Pneumonia; Pulmonary Edema; Rabbits; Thiobarbituric Acid Reactive Substances; Time Factors | 2015 |
Enhancement of the acrolein-induced production of reactive oxygen species and lung injury by GADD34.
Topics: Acetylcysteine; Acrolein; Animals; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cells; Female; Inflammation; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering | 2015 |
Attenuation of pulmonary inflammation after exposure to blast overpressure by N-acetylcysteine amide.
Topics: Acetylcysteine; Animals; Antioxidants; CD11b Antigen; Chemokine CCL2; Chemokine CXCL1; Glutathione Reductase; Heme Oxygenase-1; Lung Injury; Macrophage Inflammatory Proteins; Male; Neutrophil Infiltration; Peroxidase; Pneumonia; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2009 |
Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome.
Topics: Acetylcysteine; Activating Transcription Factors; Animals; Antidotes; Antioxidants; Blood Proteins; Cell Proliferation; Cyclin D1; Disease Models, Animal; Erythrocytes; Guinea Pigs; Liposomes; Lung; Lung Injury; Male; Mitogen-Activated Protein Kinases; Mustard Gas; Neutrophil Infiltration; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pulmonary Eosinophilia; Time Factors; Tocopherols; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2009 |
NAC is associated with additional alleviation of lung injury induced by invasive pulmonary aspergillosis in a neutropenic model.
Topics: Acetylcysteine; Amphotericin B; Animals; Antifungal Agents; Disease Models, Animal; Humans; Interleukin-10; Invasive Pulmonary Aspergillosis; Lung Injury; Male; Mice; Mice, Inbred BALB C; Neutropenia; Oxidative Stress; Random Allocation; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2009 |
[Protective effect of N-acetylcysteine on hyperoxic lung injury and its relation with p38 mitogen-activated protein kinase signaling pathway].
Topics: Acetylcysteine; Animals; Disease Models, Animal; Hyperoxia; Lung Injury; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Random Allocation; Rats; Rats, Wistar; Signal Transduction | 2010 |
N-(2-mercaptopropionyl)-glycine but not allopurinol prevented cigarette smoke-induced alveolar enlargement in mouse.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Disease Models, Animal; Emphysema; Glycine; Lung Injury; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Pulmonary Alveoli; Smoking; Sulfhydryl Compounds; Tobacco Smoke Pollution | 2011 |
Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation.
Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line; Cytochromes c; Epithelial Cells; Hyperoxia; JNK Mitogen-Activated Protein Kinases; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidants; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Respiration, Artificial; Tidal Volume | 2011 |
The role of N-acetyl-cysteine in the lung remote injury after hepatic ischemia and reperfusion in rabbits.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Glucose; Infusions, Intravenous; Liver; Lung Injury; Male; Rabbits; Random Allocation; Reperfusion Injury; Time Factors | 2012 |
Effect of N-acetylcysteine on lung injury induced by skeletal muscle ischemia-reperfusion. Histopathlogical study in rat model.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Free Radical Scavengers; Lung; Lung Injury; Male; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Treatment Outcome | 2012 |
Evaluation of N-acetylcysteine treatment in acute pancreatitis-induced lung injury.
Topics: Acetylcysteine; Amylases; Animals; Chemokine CCL2; Chemokine CXCL1; Disease Models, Animal; Free Radical Scavengers; Lung; Lung Injury; Male; Pancreatitis; Peroxidase; Rats; Rats, Wistar; RNA, Messenger; Taurocholic Acid | 2012 |
Effect of N-acetylcysteine on pulmonary cell death in a controlled hemorrhagic shock model in rats.
Topics: Acetylcysteine; Animals; Caspase 3; Cell Death; Disease Models, Animal; Fluid Therapy; In Situ Nick-End Labeling; Lung; Lung Injury; Male; Rats; Resuscitation; Shock, Hemorrhagic; Time Factors | 2012 |
Acute lung injury in experimental pancreatitis in rats: pulmonary protective effects of crotapotin and N-acetylcysteine.
Topics: Acetylcysteine; Acute Disease; Animals; Crotoxin; Drug Interactions; Lung; Lung Injury; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar | 2002 |
[Protective effect of N-acetyl-L-cysteine on liver and lung injury in mice after partial hepatic ischemia/reperfusion].
Topics: Acetylcysteine; Alanine Transaminase; Animals; Antioxidants; Disease Models, Animal; Liver; Lung; Lung Injury; Mice; Mice, Inbred BALB C; Random Allocation; Reperfusion Injury; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2007 |
N-acetyl cysteine attenuates acute lung injury in the rat.
Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Capillary Permeability; CD11 Antigens; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Glutathione; Hemorrhage; Lipid Peroxidation; Lipopolysaccharides; Liver; Lung; Lung Diseases; Lung Injury; Male; Neutrophil Activation; Neutrophils; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 1997 |
Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats.
Topics: Acetylcysteine; Acute Disease; Alcohol Drinking; Animals; Bacterial Toxins; Bronchoalveolar Lavage Fluid; Causality; Cell Survival; Chemotherapy, Cancer, Regional Perfusion; Endotoxins; Ethanol; Glutathione; Homeostasis; Lung; Lung Injury; Male; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine | 1998 |
Oxygen-induced pulmonary injury in gamma-glutamyl transpeptidase-deficient mice.
Topics: Acetylcysteine; Animals; Cysteine; gamma-Glutamyltransferase; Glutamate-Cysteine Ligase; Glutathione; Hyperoxia; Lung; Lung Injury; Mice; RNA | 2001 |