acetylcysteine and Chemical Dependence

acetylcysteine has been researched along with Chemical Dependence in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's2 (11.76)29.6817
2010's11 (64.71)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Abbaszadeh-Mashkani, S; Banafshe, HR; Boroumand, H; Dehkohneh, SG; Ghaderi, A; Hazegh, P; Mamsharifi, P; Matini, AH; Ostadmohammady, F; Padoei, F1
Carpenter, MJ; Gray, KM; Magruder, KM; McClure, EA; Squeglia, LM; Tomko, RL; Wolf, BJ1
Filip, M; Frankowska, M; Smaga, I1
Berk, M; Brietzke, E; Cordeiro, Q; Duailibi, MS; LaRowe, S; Ribeiro, M; Trevizol, AP1
Kalivas, PW; Townsend, DM; Uys, JD; Womersley, JS1
Kalivas, PW; Spencer, S1
Gorelick, DA1
Brown, RM; Kalivas, PW; Kupchik, YM1
Gipson, CD; Gray, KM; Kalivas, PW; Malcolm, RJ; McClure, EA1
Kalivas, PW; Roberts-Wolfe, DJ1
Back, SE; Brady, KT; DeSantis, SM; Gray, KM; Gros, DF; Hamner, MB; Kalivas, PW; Korte, KJ; Leavitt, V; Malcolm, R; McCauley, JL1
Zhou, W1
Hoffman, RS1
Brent, J; Finkelstein, Y; Gorodetsky, R; Schwartz, T; Wax, PM; Wiegand, TJ1
Abdulhameed, O; Baker, DA; Grier, MD; Hearing, M; Kau, KS; Lobner, D; Madayag, A; Mantsch, JR1
Akane, A; Hasegawa, M; Matsubara, K; Shiono, H; Takahashi, S1
Broughan, TA; Soloway, RD1

Reviews

5 review(s) available for acetylcysteine and Chemical Dependence

ArticleYear
N-acetylcysteine in substance use disorder: a lesson from preclinical and clinical research.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:5

    Topics: Acetylcysteine; Animals; Drug-Seeking Behavior; Expectorants; Extinction, Psychological; Humans; Substance-Related Disorders

2021
N-acetylcysteine in the treatment of craving in substance use disorders: Systematic review and meta-analysis.
    The American journal on addictions, 2017, Volume: 26, Issue:7

    Topics: Acetylcysteine; Craving; Humans; Neurotransmitter Agents; Substance-Related Disorders; Treatment Outcome

2017
Targeting redox regulation to treat substance use disorder using N‐acetylcysteine
    The European journal of neuroscience, 2019, Volume: 50, Issue:3

    Topics: Acetylcysteine; Animals; Cocaine-Related Disorders; Drug Delivery Systems; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Substance-Related Disorders

2019
Potential role of N-acetylcysteine in the management of substance use disorders.
    CNS drugs, 2014, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Molecular Structure; Substance Withdrawal Syndrome; Substance-Related Disorders; Treatment Outcome

2014
Glutamate Transporter GLT-1 as a Therapeutic Target for Substance Use Disorders.
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:6

    Topics: Acetylcysteine; Animals; Ceftriaxone; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Neurotransmitter Uptake Inhibitors; Substance-Related Disorders

2015

Trials

3 trial(s) available for acetylcysteine and Chemical Dependence

ArticleYear
The therapeutic effect of N-acetylcysteine as an add-on to methadone maintenance therapy medication in outpatients with substance use disorders: A randomized, double-blind, placebo-controlled clinical trial.
    Brain and behavior, 2023, Volume: 13, Issue:1

    Topics: Acetylcysteine; Adolescent; Adult; Antioxidants; Double-Blind Method; Humans; Methadone; Middle Aged; Outpatients; Substance-Related Disorders; Young Adult

2023
Who responds to a multi-component treatment for cannabis use disorder? Using multivariable and machine learning models to classify treatment responders and non-responders.
    Addiction (Abingdon, England), 2023, Volume: 118, Issue:10

    Topics: Acetylcysteine; Adult; Cannabinoids; Cannabis; Humans; Marijuana Abuse; Research Design; Substance-Related Disorders

2023
A Double-Blind, Randomized, Controlled Pilot Trial of N-Acetylcysteine in Veterans With Posttraumatic Stress Disorder and Substance Use Disorders.
    The Journal of clinical psychiatry, 2016, Volume: 77, Issue:11

    Topics: Acetylcysteine; Adult; Alcoholism; Cognitive Behavioral Therapy; Combat Disorders; Combined Modality Therapy; Comorbidity; Craving; Diagnosis, Dual (Psychiatry); Double-Blind Method; Female; Humans; Male; Middle Aged; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Veterans

2016

Other Studies

9 other study(ies) available for acetylcysteine and Chemical Dependence

ArticleYear
Reply to: N-Acetylcysteine in Treatment of Substance Use Disorders.
    Biological psychiatry, 2019, 06-01, Volume: 85, Issue:11

    Topics: Acetylcysteine; Dronabinol; Humans; Neuronal Plasticity; Nucleus Accumbens; Substance-Related Disorders

2019
N-Acetylcysteine in Treatment of Substance Use Disorders.
    Biological psychiatry, 2019, 06-01, Volume: 85, Issue:11

    Topics: Acetylcysteine; Dronabinol; Humans; Neuronal Plasticity; Nucleus Accumbens; Substance-Related Disorders

2019
The story of glutamate in drug addiction and of N-acetylcysteine as a potential pharmacotherapy.
    JAMA psychiatry, 2013, Volume: 70, Issue:9

    Topics: Acetylcysteine; Animals; Brain; Clinical Trials as Topic; Disease Models, Animal; Glutamic Acid; Receptors, Glutamate; Substance-Related Disorders

2013
Normalizing drug-induced neuronal plasticity in nucleus accumbens weakens enduring drug-seeking behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:1

    Topics: Acetylcysteine; Animals; Central Nervous System Agents; Dendritic Spines; Humans; Neuronal Plasticity; Neurons; Nucleus Accumbens; Substance-Related Disorders

2010
Toxicology from across the pond.
    The journal of the Royal College of Physicians of Edinburgh, 2010, Volume: 40, Issue:2

    Topics: Acetylcysteine; Animals; Antidotes; Child; Fat Emulsions, Intravenous; Humans; Naloxone; Poisoning; Risk Factors; Substance-Related Disorders; Suicide

2010
The Toxicology Investigators Consortium Case Registry--the 2011 experience.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Antidepressive Agents; Child; Child, Preschool; Databases, Factual; Drug Overdose; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Oxycodone; Prospective Studies; Psychotropic Drugs; Registries; Substance-Related Disorders; Young Adult

2012
Repeated N-acetylcysteine administration alters plasticity-dependent effects of cocaine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Dec-19, Volume: 27, Issue:51

    Topics: Acetylcysteine; Animals; Cocaine; Compulsive Behavior; Drug Administration Schedule; Male; Motor Activity; Neuronal Plasticity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders

2007
Detection and measurement of S-benzyl-N-acetylcysteine in urine of toluene sniffers using capillary gas chromatography.
    Archives of toxicology, 1993, Volume: 67, Issue:9

    Topics: Acetylcysteine; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Substance-Related Disorders; Toluene

1993
Acetaminophen hepatoxicity.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Child; Child, Preschool; Drug Overdose; Female; Humans; Liver; Male; Middle Aged; Poisoning; Pregnancy; Pregnancy in Adolescence; Substance-Related Disorders; Suicide; Suicide, Attempted

2000