acetylcysteine has been researched along with Cerebral Ischemia in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (61.29) | 29.6817 |
| 2010's | 9 (29.03) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M | 1 |
| Alam, MM; Ali, M; Parvez, S; Tabassum, H | 1 |
| Lee, SR; Lee, YH | 1 |
| Choi, BY; Hong, DK; Jeong, JH; Kang, BS; Kang, DH; Kho, AR; Lee, SH; Lim, MS; Park, KH; Park, MK; Suh, SW | 1 |
| Budziszewska, B; Bystrowska, B; Filip, M; Krzyżanowska, W; Pera, J; Pomierny, B; Pomierny-Chamioło, L | 1 |
| Baratashvili, N; Kandelaki, M; Samsonia, M | 1 |
| Furukawa, LNS; Pereira, RC; Romão, CM; Shimizu, MHM | 1 |
| Liu, KJ; Shi, H; Taheri, S; Yan, J; Zhang, Z | 1 |
| Buelow, M; Fatemi, A; Getzenberg, R; Johnston, M; Kannan, RM; Kannan, S; Mishra, MK; Nance, E; Porambo, M; Zhang, F | 1 |
| Jin, X; Liu, CF; Liu, KJ; Liu, W; Liu, WC; Liu, Y; Pan, R; Shen, X; Shu, H; Sun, Y; Wang, X | 1 |
| Beyhun, E; Cekic Gonenc, O; Demir, S; Gunduz, A; Karaca, Y; Mentese, A; Sahin, A; Turedi, S; Turkmen, S; Yulug, E | 1 |
| Bukina, SJ; Inchina, VI | 1 |
| Chen, L; Liang, S; Wang, R; Yue, H | 1 |
| Adams, J; Dave, JR; Elliott, PJ; Hale, SL; Moffett, JR; Tortella, FC; Williams, AJ | 1 |
| Meng, F; Tian, H; Zhang, G; Zhang, Q | 1 |
| Li, Z; Pan, D | 1 |
| Li, H; Tian, H; Zhang, G; Zhang, Q | 2 |
| Guo, J; Meng, F; Zhang, G; Zhang, Q | 1 |
| Fu, X; Tian, H; Zhang, G; Zhang, Q | 1 |
| Shen, WH; Zhang, CY; Zhang, GY | 1 |
| Adams, J; Berti, R; Dave, JR; Elliot, PJ; Tortella, FC; Williams, AJ | 1 |
| Gilg, AG; Giri, S; Jatana, M; Khan, M; Sekhon, B; Sekhon, C; Singh, AK; Singh, I | 1 |
| Cohn, SI; Lu, XC; Myers, TM; Sharrow, KM; Tortella, FC; Williams, AJ | 1 |
| Gabryel, B; Małecki, A; Toborek, T | 1 |
| Guan, QH; Pei, DS; Sun, YF; Xu, TL; Zhang, GY; Zhang, QX | 1 |
| Dave, JR; Tortella, FC; Williams, AJ | 1 |
| Li, HC; Tian, H; Zhang, GY; Zhang, QG | 1 |
| Calabrò, G; Caputi, AP; Costantino, G; Cucinotta, G; Cuzzocrea, S; De Sarro, A; Dugo, L; Mazzon, E; Serraino, I | 1 |
| Dirnagl, U; Gieche, J; Grune, T; Harms, C; Ruscher, K; Schmitt, M; Weih, M | 1 |
| Adams, J; Chopp, M; Elliott, PJ; Lu, M; Zhang, L; Zhang, RL; Zhang, ZG | 1 |
1 review(s) available for acetylcysteine and Cerebral Ischemia
| Article | Year |
|---|---|
Neuroprotection with the proteasome inhibitor MLN519 in focal ischemic brain injury: relation to nuclear factor kappaB (NF-kappaB), inflammatory gene expression, and leukocyte infiltration.
Topics: Acetylcysteine; Animals; Brain Infarction; Brain Ischemia; Chemotaxis, Leukocyte; Encephalitis; Enzyme Inhibitors; Gene Expression; Humans; Neuroprotective Agents; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2006 |
30 other study(ies) available for acetylcysteine and Cerebral Ischemia
| Article | Year |
|---|---|
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia.
Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics | 2011 |
N-acetyl-L-cysteine ameliorates mitochondrial dysfunction in ischemia/reperfusion injury via attenuating Drp-1 mediated mitochondrial autophagy.
Topics: Acetylcysteine; Animals; Autophagy; Brain Ischemia; Dynamins; Free Radical Scavengers; Male; Mitochondria; Mitochondrial Dynamics; Rats; Rats, Wistar; Reperfusion Injury | 2022 |
Neuroprotective effects of N-acetylcysteine via inhibition of matrix metalloproteinase in a mouse model of transient global cerebral ischemia.
Topics: Acetylcysteine; Animals; Brain; Brain Ischemia; Disease Models, Animal; Hippocampus; Injections, Intraperitoneal; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents | 2020 |
Transient Receptor Potential Melastatin 2 (TRPM2) Inhibition by Antioxidant,
Topics: Acetylcysteine; Animals; Antioxidants; Brain Ischemia; Glutathione; Hippocampus; Lipid Peroxidation; Neuroglia; Neurons; Rats; TRPM Cation Channels; Zinc | 2020 |
Ceftriaxone- and N-acetylcysteine-induced brain tolerance to ischemia: Influence on glutamate levels in focal cerebral ischemia.
Topics: Acetylcysteine; Amino Acid Transport Systems, Acidic; Animals; Astrocytes; Brain Ischemia; Ceftriaxone; Excitatory Amino Acid Transporter 2; Frontal Lobe; Gene Expression Regulation; Glutamic Acid; Hippocampus; Humans; Infarction, Middle Cerebral Artery; Rats; Synaptic Transmission | 2017 |
[EVALUATION OF NEUROPROTECTIVE ACTIVITY OF COMPLEX IMPACT OF MAGNESIUM OF SULFATE, LAMOTRYGINE AND N-ACETYLCYSTEINE UNDER CONDITIONS OF COMBINED NORMOBARIC HYPOXIA WITH LIGATION OF RIGHT CAROTID ARTERY IN RATS].
Topics: Acetylcysteine; Administration, Oral; Animals; Animals, Outbred Strains; Brain Ischemia; Carotid Arteries; Cerebrovascular Disorders; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Injections, Intraperitoneal; Lamotrigine; Magnesium Sulfate; Male; Neuroprotective Agents; Rats; Stroke | 2018 |
N-acetyl-l-cysteine exacerbates kidney dysfunction caused by a chronic high-sodium diet in renal ischemia and reperfusion rats.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Blood Pressure; Brain Ischemia; Free Radical Scavengers; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Sodium Chloride, Dietary | 2019 |
Hypoxia-inducible factor 1 contributes to N-acetylcysteine's protection in stroke.
Topics: Acetylcysteine; Animals; Brain Ischemia; Disease Models, Animal; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Infarction, Middle Cerebral Artery; Neuroprotective Agents; Rats; Reperfusion Injury; Signal Transduction; Stroke | 2014 |
Systemic dendrimer-drug treatment of ischemia-induced neonatal white matter injury.
Topics: Acetylcysteine; Animals; Animals, Newborn; Astrocytes; Brain; Brain Ischemia; Cell Movement; Cell Proliferation; Cytokines; Dendrimers; Densitometry; Drug Delivery Systems; Female; Mice; Microglia; Myelin Sheath; Oligodendroglia; Pregnancy; RNA; White Matter | 2015 |
Normobaric Hyperoxia Extends Neuro- and Vaso-Protection of N-Acetylcysteine in Transient Focal Ischemia.
Topics: Acetylcysteine; Animals; Blood-Brain Barrier; Brain Ischemia; Hyperoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Infarction, Middle Cerebral Artery; Male; Neuroprotection; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Vascular Endothelial Growth Factor A | 2017 |
The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke.
Topics: Acetylcysteine; Animals; Brain; Brain Ischemia; Carotid Arteries; Cell Count; Female; Free Radical Scavengers; Neurons; Pyruvates; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke | 2016 |
Neuroprotective activity of mexidole and 3-hydroxypyridine acetylcysteinate against the background of cerebral ischemia in the complex of experimental diabetes mellitus and exogenous hypercholesterolemia.
Topics: Acetylcysteine; Animals; Brain Ischemia; Diabetes Mellitus, Experimental; Female; Hypercholesterolemia; Male; Neuroprotective Agents; Picolines; Rats; Treatment Outcome | 2008 |
Using a novel in vivo model to study the function of nuclear factor kappa B in cerebral ischemic injury.
Topics: Acetylcysteine; Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; I-kappa B Proteins; Male; Mutant Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Rats, Wistar; Transcription Factor RelA | 2012 |
Delayed treatment with MLN519 reduces infarction and associated neurologic deficit caused by focal ischemic brain injury in rats via antiinflammatory mechanisms involving nuclear factor-kappaB activation, gliosis, and leukocyte infiltration.
Topics: Acetylcysteine; Animals; Astrocytes; Brain Ischemia; Cell Movement; Cysteine Endopeptidases; Gliosis; Infarction, Middle Cerebral Artery; Inflammation Mediators; Leukocytes; Male; Multienzyme Complexes; Nerve Degeneration; Nervous System Diseases; NF-kappa B; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Recovery of Function | 2003 |
Biphasic activation of apoptosis signal-regulating kinase 1-stress-activated protein kinase 1-c-Jun N-terminal protein kinase pathway is selectively mediated by Ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors involving oxidat
Topics: Acetylcysteine; Animals; Antioxidants; Brain Ischemia; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Enzyme Activation; Hippocampus; Ion Channel Gating; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Nifedipine; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Spermine | 2003 |
[Effect of neuroprotectant agent combined with cocktail on expression of anti-apoptotic protein bcl-2 in rats after focal cerebral ischemia].
Topics: Acetylcysteine; Actins; Animals; Brain Ischemia; Dizocilpine Maleate; Drug Therapy, Combination; Fructosediphosphates; Male; Molecular Weight; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2002 |
Antioxidant NAC and AMPA/KA receptor antagonist DNQX inhibited JNK3 activation following global ischemia in rat hippocampus.
Topics: Acetylcysteine; Animals; Brain Ischemia; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Immunoblotting; Ketamine; Male; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinases; Nifedipine; Protein Transport; Protein-Tyrosine Kinases; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Free radicals are involved in continuous activation of nonreceptor tyrosine protein kinase c-Src after ischemia/reperfusion in rat hippocampus.
Topics: Acetylcysteine; Animals; Brain Ischemia; CSK Tyrosine-Protein Kinase; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Free Radicals; Hippocampus; Immunoblotting; Ketamine; Male; Phosphopyruvate Hydratase; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Reperfusion; src-Family Kinases; Sulfur Isotopes; Time Factors | 2003 |
Antioxidant N-acetylcysteine and AMPA/KA receptor antagonist DNQX inhibited mixed lineage kinase-3 activation following cerebral ischemia in rat hippocampus.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Ischemia; Enzyme Activation; Excitatory Amino Acid Antagonists; Hippocampus; Male; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase Kinase Kinase 11; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid | 2003 |
Delayed activation and regulation of MKK7 in hippocampal CA1 region following global cerebral ischemia in rats.
Topics: Acetylcysteine; Animals; Brain Ischemia; Enzyme Activation; Hippocampus; Male; MAP Kinase Kinase 7; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2003 |
Antioxidants attenuate reperfusion injury after global brain ischemia through inhibiting nuclear factor-kappa B activity in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Brain Ischemia; Hippocampus; I-kappa B Proteins; Male; Neurons; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Phosphorylation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Thiocarbamates; Transcription Factor RelA | 2003 |
Delayed treatment of ischemia/reperfusion brain injury: extended therapeutic window with the proteosome inhibitor MLN519.
Topics: Acetylcysteine; Animals; Biomarkers; Brain Chemistry; Brain Ischemia; Chemotherapy, Adjuvant; Disease Models, Animal; E-Selectin; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Inflammation; Intercellular Adhesion Molecule-1; Male; Neuroprotective Agents; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2004 |
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
Topics: Acetylcysteine; Animals; Brain Ischemia; Cerebrovascular Circulation; Cytokines; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Ectodysplasins; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Inflammation; Ischemic Attack, Transient; Male; Membrane Proteins; Neurologic Examination; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazolium Salts; Time Factors | 2004 |
Recovery from ischemic brain injury in the rat following a 10 h delayed injection with MLN519.
Topics: Acetylcysteine; Animals; Brain Ischemia; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Recovery of Function; Time Factors | 2005 |
Immunosuppressive immunophilin ligands attenuate damage in cultured rat astrocytes depleted of glutathione and exposed to simulated ischemia in vitro. Comparison with N-acetylcysteine.
Topics: Acetylcysteine; Animals; Apoptosis; Astrocytes; Benzimidazoles; Brain Ischemia; Cell Separation; Cells, Cultured; Cyclosporine; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Immunophilins; Immunosuppressive Agents; Ligands; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Tacrolimus; Tetrazolium Salts; Thiazoles | 2005 |
N-Acetylcysteine inhibit the translocation of mixed lineage kinase-3 from cytosol to plasma membrane during transient brain ischemia in rat hippocampus.
Topics: Acetylcysteine; Animals; Brain Ischemia; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Hippocampus; Male; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase Kinase Kinase 11; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Antioxidant N-acetylcysteine inhibits the activation of JNK3 mediated by the GluR6-PSD95-MLK3 signaling module during cerebral ischemia in rat hippocampus.
Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Brain Ischemia; Disease Models, Animal; Disks Large Homolog 4 Protein; Enzyme Activation; Gene Expression Regulation; GluK2 Kainate Receptor; Hippocampus; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Kinase Kinase 11; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Signal Transduction; Time Factors | 2006 |
Beneficial effects of n-acetylcysteine on ischaemic brain injury.
Topics: Acetylcysteine; Animals; Brain; Brain Edema; Brain Ischemia; Free Radical Scavengers; Gerbillinae; Male; Malondialdehyde; Motor Activity; Nitric Oxide; Peroxidase; Poly(ADP-ribose) Polymerases; Reperfusion Injury; Time Factors; Tyrosine | 2000 |
Proteolysis of oxidized proteins after oxygen-glucose deprivation in rat cortical neurons is mediated by the proteasome.
Topics: Acetylcysteine; Animals; Brain Ischemia; Cell Death; Cells, Cultured; Cerebral Cortex; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Glucose; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Oxidative Stress; Oxygen; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Reactive Oxygen Species | 2001 |
Postischemic (6-Hour) treatment with recombinant human tissue plasminogen activator and proteasome inhibitor PS-519 reduces infarction in a rat model of embolic focal cerebral ischemia.
Topics: Acetylcysteine; Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain Ischemia; Cell Count; Cerebral Hemorrhage; Cerebral Infarction; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Intracranial Embolism; Male; Multienzyme Complexes; Neurologic Examination; Peroxidase; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Recombinant Proteins; Time Factors; Tissue Plasminogen Activator | 2001 |