Compounds > acetylcysteine

acetylcysteine and Cell Transformation, Neoplastic

acetylcysteine has been researched along with Cell Transformation, Neoplastic in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (20.00)18.2507
2000's18 (45.00)29.6817
2010's12 (30.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Chen, W; Chen, YH; Ruan, Q; Sun, H; Tang, A; Wan, X; Wang, J; Yan, D; Yang, X; Zamani, A; Zhang, H1
Adnot, S; Bernard, D; Breau, M; Mechta-Grigoriou, F1
Brooks, MD; Buschhaus, JM; Conley, S; Davis, A; Fath, MA; Gheordunescu, E; Harouaka, R; Jiagge, E; Lozier, A; Luker, GD; Luo, M; McDermott, S; Merajver, SD; Shang, L; Spitz, DR; Triner, D; Wang, Y; Wicha, MS; Zhu, Y1
Fujii, M; Furuta, S; Gorlach, A; Hasegawa, H; Kamata, T; Kaneda, K; Kato, M; Koike, K; Morishita, K; Shigemura, T; Shiohara, M1
He, JD; Li, SP; Shen, ZY; Wang, CY; Wang, Z; Xu, HX; Xu, YJ; Yao, Z; Yu, Y; Zhang, HM; Zhang, JJ; Zhang, RX1
Baek, SJ; Eling, TE; Hara, Y; Lee, SH; McEntee, MF; Sukhthankar, M; Yamaguchi, K1
Hanausek, M; Kinjo, T; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Walaszek, Z1
Banerjee, S; Banki, K; Barcza, M; Barrett, D; Doherty, E; Fernandez, DR; Garba, A; Hanczko, R; Landas, SK; Middleton, FA; Niland, B; Perl, A; Qian, Y; Telarico, T; Vas, G1
Carlsson, G; Dahl, N; Fadeel, B; Fröjmark, AS; Grzybowska, E; Jitkaew, S; Lehtiö, J; Nordström, A; Trebinska, A1
Beseler, C; Cavalieri, EL; Rogan, EG; Saeed, M; Zahid, M1
Chodaparambil, JV; Felsher, DW; Huang, M; Kusler, B; Mitchell, BS; Pollyea, DA; Whang, P; Xu, L1
Hanczko, R; Landas, S; Oaks, Z; Perl, A; Telarico, T1
Han, CY; Hien, TT; Kang, KW; Lim, SC1
Gillissen, A1
Emilio, R; Mahara, V; Martín, SA1
Chung, KF; Huang, CD; Huang, TT; Kuo, HP; Lee, KY; Lin, HC; Lin, SM; Lo, YL; Wang, CH1
Cavallin, LE; Chiozzini, C; Goldschmidt-Clermont, PJ; Leung, HJ; Ma, Q; Mesri, EA1
Attia, A; Isom, S; Kock, ND; McBride, JE; Miller, MS; Moore, JE; Munley, MT; Walb, MC1
Barrett, JC; French, JE; Kari, FW; Martin, KR; Saulnier, MJ1
Bae, GU; Cho, EJ; Choi, WS; Han, JW; Han, SH; Jung, DK; Kang, H; Kim, YK; Lee, HW; Lee, HY; Seo, DW1
Poon, RY; Woo, RA1
Maru, Y; Tsukahara, F; Zhang, Q1
Efremova, T; Gamaley, I; Kever, L; Khaitlina, S; Kirpichnikova, K; Komissarchik, Y; Polozov, Y1
Rosen, JM; Schwertfeger, KL; Xian, W1
Corpet, DE; Guéraud, F; Pierre, F; Santarelli, R; Taché, S1
Campos, AC; Carneiro, CR; Correa, M; D'Almeida, V; Galdieri, LC; Jasiulionis, MG; Melo, FH; Molognoni, F1
Cavalieri, EL; Chakravarti, D; Mailander, PC; Meza, JL; Rogan, EG; Venugopal, D; Zahid, M1
Barrett, JC; Carothers, AM; Chiao, C; Grunberger, D; Preston, GA; Solomon, G1
Fésüs, L; Szondy, Z; Uray, I1
Der, CJ; Fearon, ER; Finkel, T; Goldschmidt-Clermont, PJ; Irani, K; Sollott, SJ; Sundaresan, M; Xia, Y; Zweier, JL1
Chu, SW; Ho, YS; Lien, HJ; Lin, JK; Liu, TH; Wang, YJ1
Benehacene, A; Kamps, M; Scheele, JS; White, FC1
Castranova, V; Colburn, NH; Ding, M; Leonard, SS; Li, JJ; Shi, X; Vallyathan, V; Ye, JP1
Hojo, K; Nishida, K; Omi, K; Omura, S; Sonoda, H; Sugita, K1
Arrigo, AP; Diaz-Latoud, C; Gonin, S; Imbo, A; Manero, F; Richard, MJ; Ursini, MV1
Balansky, RM; Camoirano, A; D'Agostini, F; de Flora, S1
Adler, G; Böhm, BO; Dralle, H; Hoang-Vu, C; Kessler, H; Ludwig, L; Schmid, RM; Wagner, M1
Béchet, DM; Ferrara, M; Obled, A; Omura, S; Roux, MP; Tournu, C1
Friedman, MA; Kamendulis, LM; Klaunig, JE; Park, J1
Brash, DE; Havre, PA; McCormick, JJ; O'Reilly, S1

Reviews

2 review(s) available for acetylcysteine and Cell Transformation, Neoplastic

ArticleYear
Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase.
    Trends in molecular medicine, 2011, Volume: 17, Issue:7

    Topics: Acetylcysteine; Animals; Autoimmunity; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Fatty Liver; Glucose; Humans; Infertility, Male; Inflammation; Male; Mitochondria; Oxidative Stress; Pentose Phosphate Pathway; Sperm Motility; Transaldolase

2011
Probing the molecular program of apoptosis by cancer chemopreventive agents.
    Journal of cellular biochemistry. Supplement, 1995, Volume: 22

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Cell Count; Cell Transformation, Neoplastic; Mice; Retinoids; Sodium Salicylate; Thymus Gland

1995

Other Studies

38 other study(ies) available for acetylcysteine and Cell Transformation, Neoplastic

ArticleYear
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis.
    The Journal of experimental medicine, 2020, 02-03, Volume: 217, Issue:2

    Topics: Acetylcysteine; Adoptive Transfer; Animals; Carcinogenesis; Cell Polarity; Cell Transformation, Neoplastic; Female; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myeloid Cells; Myeloid-Derived Suppressor Cells; Reactive Oxygen Species; Signal Transduction; Transfection

2020
[Antioxidant treatment promotes lung cancer while protecting against lung emphysema].
    Medecine sciences : M/S, 2020, Volume: 36, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Cell Transformation, Neoplastic; Cellular Senescence; Cytoprotection; Humans; Lung; Lung Neoplasms; Mice; Mice, Knockout; Oxidative Stress; Proto-Oncogene Proteins c-jun; Pulmonary Emphysema

2020
Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling.
    Cell metabolism, 2018, Jul-03, Volume: 28, Issue:1

    Topics: Acetylcysteine; AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Glucose; Glutathione; Glycolysis; Humans; Mice, Inbred NOD; Neoplastic Stem Cells; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Protein Kinases; Reactive Oxygen Species; Signal Transduction; Stress, Physiological; Thioredoxins; Xenograft Model Antitumor Assays

2018
Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype.
    Journal of virology, 2015, Volume: 89, Issue:17

    Topics: Acetylcysteine; Cell Line, Transformed; Cell Movement; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Human T-lymphotropic virus 1; Humans; Interleukin-2; Janus Kinases; Leukemia-Lymphoma, Adult T-Cell; Membrane Proteins; NADPH Oxidase 5; NADPH Oxidases; Onium Compounds; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; STAT5 Transcription Factor; Tumor Suppressor Proteins; Up-Regulation

2015
LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 signaling pathway.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Acetylcysteine; Aged; Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Epithelial-Mesenchymal Transition; Female; Humans; Lentivirus; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; RNA, Long Noncoding; RNA, Small Interfering; Signal Transduction; Zinc Finger E-box-Binding Homeobox 1

2016
A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Acetylcysteine; Adenomatous Polyposis Coli; Animals; Antineoplastic Agents, Phytogenic; Camellia sinensis; Catechin; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cycloheximide; Cysteine Proteinase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Genes, APC; HCT116 Cells; HT29 Cells; Humans; Mice; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Time Factors; Transfection

2008
Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention.
    Carcinogenesis, 2009, Volume: 30, Issue:6

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Carotenoids; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Ellagic Acid; Female; Free Radical Scavengers; Free Radicals; Genes, ras; Keratinocytes; Lycopene; Mice; Mutation; Plant Extracts; Proto-Oncogene Proteins p21(ras); Resveratrol; Skin Neoplasms; Stilbenes; Triterpenes; Ursolic Acid; Vitis

2009
Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.
    The Journal of clinical investigation, 2009, Volume: 119, Issue:6

    Topics: Acetylcysteine; alpha-Fetoproteins; Animals; Apoptosis; beta Catenin; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; fas Receptor; JNK Mitogen-Activated Protein Kinases; Liver Failure; Liver Neoplasms; Male; Mice; Mice, Knockout; Mitochondria; Phosphorylation; Transaldolase

2009
N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1.
    The Journal of biological chemistry, 2009, Oct-09, Volume: 284, Issue:41

    Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Antioxidants; Apoptosis; B-Lymphocytes; Baculoviral IAP Repeat-Containing 3 Protein; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Coumarins; Cysteine; Dose-Response Relationship, Drug; Down-Regulation; Fluorescent Dyes; Herpesvirus 4, Human; Humans; Inhibitor of Apoptosis Proteins; Jurkat Cells; Mitochondria; NF-kappa B; Oligopeptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Tosylphenylalanyl Chloromethyl Ketone; Transcription, Genetic; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein

2009
Resveratrol and N-acetylcysteine block the cancer-initiating step in MCF-10F cells.
    Free radical biology & medicine, 2011, Jan-01, Volume: 50, Issue:1

    Topics: Acetylcysteine; Anticarcinogenic Agents; Breast Neoplasms; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Female; Humans; Mammary Glands, Human; Models, Biological; Resveratrol; Stilbenes

2011
Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.
    The Journal of biological chemistry, 2011, Apr-01, Volume: 286, Issue:13

    Topics: Acetylcysteine; Animals; Blast Crisis; Carrier Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Cysteine Proteinase Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Leukemic; GTP-Binding Proteins; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leupeptins; Lymphoma; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Neoplasms, Experimental; Nuclear Proteins; Oxidants; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Multimerization; Proto-Oncogene Proteins c-myc; RNA-Binding Proteins

2011
Role of Pin1 in UVA-induced cell proliferation and malignant transformation in epidermal cells.
    Biochemical and biophysical research communications, 2011, Jun-24, Volume: 410, Issue:1

    Topics: Acetylcysteine; Animals; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin D1; Epidermis; Humans; Mice; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Reactive Oxygen Species; Skin Neoplasms; Transcription Factor AP-1; Ultraviolet Rays

2011
[Anti-inflammatory efficacy of N-acetylcysteine and therapeutic usefulness].
    Pneumologie (Stuttgart, Germany), 2011, Volume: 65, Issue:9

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Arthritis; Bronchitis; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Expectorants; Free Radical Scavengers; Humans; Lung Diseases; Lung Diseases, Interstitial; Pulmonary Disease, Chronic Obstructive

2011
Role of oxidative stress in transformation induced by metal mixture.
    Oxidative medicine and cellular longevity, 2011, Volume: 2011

    Topics: Acetylcysteine; Air Pollutants; Animals; Arsenic; BALB 3T3 Cells; Cadmium; Carcinogens, Environmental; Cell Survival; Cell Transformation, Neoplastic; Free Radical Scavengers; Humans; Lead; Mice; Oxidative Stress; Reactive Oxygen Species

2011
Increased activation of fibrocytes in patients with chronic obstructive asthma through an epidermal growth factor receptor-dependent pathway.
    The Journal of allergy and clinical immunology, 2012, Volume: 129, Issue:5

    Topics: Acetylcysteine; ADAM Proteins; ADAM17 Protein; Adult; Antigens, CD34; Asthma; Blood Cells; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Collagen Type I; ErbB Receptors; Female; Fibroblasts; Follow-Up Studies; Gefitinib; Humans; Hydrogen Peroxide; Leukocyte Common Antigens; Male; Middle Aged; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Quinazolines; Respiratory Function Tests; Signal Transduction; Stem Cells; Tyrphostins

2012
A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis.
    Antioxidants & redox signaling, 2013, Jan-01, Volume: 18, Issue:1

    Topics: Acetylcysteine; Angiogenesis Inhibitors; Animals; Antiviral Agents; Cell Proliferation; Cell Transformation, Neoplastic; Free Radical Scavengers; Gene Expression; HEK293 Cells; Herpesvirus 8, Human; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Neuropeptides; Oxidative Stress; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Sarcoma, Kaposi; STAT3 Transcription Factor; Transcription, Genetic; Viral Proteins

2013
Chemoprevention by N-acetylcysteine of low-dose CT-induced murine lung tumorigenesis.
    Carcinogenesis, 2013, Volume: 34, Issue:2

    Topics: Acetylcysteine; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Free Radical Scavengers; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Radiation-Induced; Nitrosamines; Tomography, X-Ray Computed

2013
Timing of supplementation with the antioxidant N-acetyl-L-cysteine reduces tumor multiplicity in novel, cancer-prone p53 haploinsufficient Tg.AC (v-Ha-ras) transgenic mice but has no impact on malignant progression.
    Nutrition and cancer, 2002, Volume: 43, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cross-Over Studies; Dietary Supplements; Disease Models, Animal; Female; Free Radical Scavengers; Genes, ras; Linear Models; Male; Mice; Mice, Transgenic; Sarcoma; Skin Neoplasms; Survival Rate; Time Factors

2002
Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase.
    Experimental cell research, 2003, Oct-15, Volume: 290, Issue:1

    Topics: Acetylcysteine; Animals; Arsenites; Carcinogens; Catalase; Cell Line; Cell Transformation, Neoplastic; Enzyme Inhibitors; Hydrogen Peroxide; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Reactive Oxygen Species; Ribosomal Protein S6 Kinases, 70-kDa; Transcription Factor AP-1

2003
Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.
    Genes & development, 2004, Jun-01, Volume: 18, Issue:11

    Topics: Acetylcysteine; Adenovirus E1A Proteins; Animals; Apoptosis; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Chromosomal Instability; Culture Media, Serum-Free; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation, Neoplastic; Genes, ras; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Reactive Oxygen Species; Tumor Suppressor Protein p53

2004
N-acetyl-cysteine enhances growth in BCR-ABL-transformed cells.
    Cancer science, 2005, Volume: 96, Issue:4

    Topics: Acetylcysteine; Animals; Blotting, Western; Cell Line, Transformed; Cell Transformation, Neoplastic; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, abl; Genes, ras; HSP90 Heat-Shock Proteins; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Oncogene Proteins v-abl; Protein-Tyrosine Kinases; Rats

2005
N-acetylcysteine-induced changes in susceptibility of transformed eukaryotic cells to bacterial invasion.
    Cell biology international, 2006, Volume: 30, Issue:4

    Topics: 3T3 Cells; Acetylcysteine; Animals; Cell Transformation, Neoplastic; Cytoskeleton; Escherichia coli; Eukaryotic Cells; Fibroblasts; Glutathione; Mice

2006
Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition.
    Molecular endocrinology (Baltimore, Md.), 2007, Volume: 21, Issue:4

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Culture Techniques; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cysteine Proteinase Inhibitors; Epithelium; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mesoderm; Mice; Mice, Transgenic; Phenotype; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-cbl; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; RNA, Small Interfering

2007
Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium.
    The British journal of nutrition, 2008, Volume: 99, Issue:5

    Topics: 1,2-Dimethylhydrazine; Acetylcysteine; Animals; Antioxidants; Body Weight; Calcium, Dietary; Cattle; Cell Transformation, Neoplastic; Colorectal Neoplasms; Diet; Eating; Feces; Female; Heme; Meat; Olive Oil; Plant Oils; Rats; Rats, Inbred F344; Thiobarbituric Acid Reactive Substances

2008
Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation.
    Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:12

    Topics: Acetylcysteine; Animals; Anoikis; Cell Adhesion; Cell Culture Techniques; Cell Transformation, Neoplastic; Cells, Cultured; Cysteine; DNA Methylation; Gene Expression Regulation; Glutathione; Homocysteine; Lipid Peroxidation; Melanocytes; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Sepharose; Superoxides; Trypsin

2007
Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 109, Issue:1-2

    Topics: Acetylcysteine; Animals; Cell Line; Cell Transformation, Neoplastic; Colony-Forming Units Assay; DNA Adducts; Epithelial Cells; Estradiol; Estrogens, Catechol; Female; Genes, ras; Mammary Glands, Animal; Mice; Mutation

2008
Apoptosis and altered redox state induced by caffeic acid phenethyl ester (CAPE) in transformed rat fibroblast cells.
    Cancer research, 1995, Aug-15, Volume: 55, Issue:16

    Topics: Acetylcysteine; Animals; Apoptosis; Caffeic Acids; Catalase; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; DNA Damage; Glutathione; Hydrogen Peroxide; Oxidation-Reduction; Phenylethyl Alcohol; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344

1995
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts.
    Science (New York, N.Y.), 1997, Mar-14, Volume: 275, Issue:5306

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA; Electron Spin Resonance Spectroscopy; Genes, ras; GTP-Binding Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Proto-Oncogene Proteins p21(ras); rac GTP-Binding Proteins; Reactive Oxygen Species; Signal Transduction; Superoxides; Transfection

1997
Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol.
    Chemico-biological interactions, 1997, Jun-06, Volume: 105, Issue:1

    Topics: 3T3 Cells; Acetylcysteine; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Chromosomes; DNA Fragmentation; Electrophoresis, Capillary; Glutathione; Hydroquinones; Mice; Mice, Inbred C3H; Pentachlorophenol; Pesticides; Tumor Suppressor Protein p53

1997
VEGF mRNA is stabilized by ras and tyrosine kinase oncogenes, as well as by UV radiation--evidence for divergent stabilization pathways.
    Growth factors (Chur, Switzerland), 1997, Volume: 14, Issue:2-3

    Topics: 3T3 Cells; Acetylcysteine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Hypoxia; Cell Transformation, Neoplastic; DNA-Binding Proteins; Endothelial Growth Factors; Genes, ras; Genistein; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Isoflavones; Lymphokines; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Protein-Tyrosine Kinases; ras Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Ultraviolet Rays; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Vanadate-induced activation of activator protein-1: role of reactive oxygen species.
    Carcinogenesis, 1999, Volume: 20, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Epidermal Cells; Formates; Free Radical Scavengers; Gene Expression Regulation; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Mice; NADP; Naphthalenes; Oxidation-Reduction; Oxygen Consumption; Protein Kinase C; Reactive Oxygen Species; Recombinant Fusion Proteins; Superoxide Dismutase; Superoxides; Transcription Factor AP-1; Transcriptional Activation; Transfection; Vanadates

1999
Suppression of oncogenic transformation by hypothemycin associated with accelerated cyclin D1 degradation through ubiquitin-proteasome pathway.
    Life sciences, 1999, Volume: 65, Issue:4

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclin D1; Cysteine Endopeptidases; DNA, Complementary; Down-Regulation; G1 Phase; Mice; Mitosporic Fungi; Multienzyme Complexes; Proteasome Endopeptidase Complex; Repressor Proteins; Schizosaccharomyces; Ubiquitins; Zearalenone

1999
p53/T-antigen complex disruption in T-antigen transformed NIH3T3 fibroblasts exposed to oxidative stress: correlation with the appearance of a Fas/APO-1/CD95 dependent, caspase independent, necrotic pathway.
    Oncogene, 1999, Dec-23, Volume: 18, Issue:56

    Topics: 3T3 Cells; Acetylcysteine; Animals; Antibodies; Antigens, Polyomavirus Transforming; Antioxidants; Apoptosis; Cell Survival; Cell Transformation, Neoplastic; fas Receptor; Mice; Necrosis; Oxidative Stress; Reactive Oxygen Species; Simian virus 40; Tumor Suppressor Protein p53; Vitamin K

1999
Interactions between N-acetylcysteine and ascorbic acid in modulating mutagenesis and carcinogenesis.
    International journal of cancer, 2000, Dec-01, Volume: 88, Issue:5

    Topics: Acetylcysteine; Animals; Ascorbic Acid; Carcinogenicity Tests; Cell Transformation, Neoplastic; Chromium; Drug Stability; Female; Lung Neoplasms; Mice; Mutagenesis; Urethane

2000
Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation.
    Cancer research, 2001, Jun-01, Volume: 61, Issue:11

    Topics: 3T3 Cells; Acetylcysteine; Animals; Apoptosis; Carcinoma, Medullary; Cell Nucleus; Cell Transformation, Neoplastic; Dimerization; DNA-Binding Proteins; DNA, Neoplasm; Drosophila Proteins; Fibroblasts; Humans; I-kappa B Kinase; I-kappa B Proteins; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; ras Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction; Thyroid Neoplasms; Transcription Factor RelA; Transcription, Genetic; Tumor Cells, Cultured

2001
Glucose regulates protein catabolism in ras-transformed fibroblasts through a lysosomal-dependent proteolytic pathway.
    The Biochemical journal, 2001, Jul-01, Volume: 357, Issue:Pt 1

    Topics: 3T3 Cells; Acetylcysteine; Animals; Cathepsin B; Cathepsin D; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Fibroblasts; Genes, ras; Glucose; Humans; Kinetics; Kirsten murine sarcoma virus; L-Lactate Dehydrogenase; Lysosomes; Methionine; Methylamines; Mice; Protein Biosynthesis; Proteins; Tumor Cells, Cultured

2001
Acrylamide-induced cellular transformation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 65, Issue:2

    Topics: Acetylcysteine; Acrylamide; Animals; Buthionine Sulfoximine; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Drug Combinations; Embryo, Mammalian; Enzyme Inhibitors; Glutathione; Mesocricetus; Triazoles

2002
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine.
    Cancer research, 2002, Mar-01, Volume: 62, Issue:5

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, myc; Humans; Neoplasms; Penicillamine; Tumor Suppressor Protein p53

2002