acetylcysteine and Cardiovascular Stroke

acetylcysteine has been researched along with Cardiovascular Stroke in 93 studies

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-19906 (6.45)18.7374
1990's12 (12.90)18.2507
2000's27 (29.03)29.6817
2010's43 (46.24)24.3611
2020's5 (5.38)2.80

Authors

AuthorsStudies
Alvarez-Leite, JI; Barreto, AS; Barreto, RSS; Braga, WF; de Souza, DS; Durço, AO; Guimarães, AG; Heimfarth, L; Lauton-Santos, S; Miguel-Dos-Santos, R; Oliveira Barreto, T; Quintans Júnior, LJ; Rabelo, TK; Rhana, P; Santana-Filho, VJ; Santos Cruz, JD; Santos Santana, MN; Santos, MRVD; Vasconcelos, CML1
Aguayo, R; Gajardo, A; Lillo-Moya, J; Panieri, E; Prieto, JC; Puentes, Á; Ramos, C; Rodrigo, R; Rojas-Solé, C; Saso, L1
Angelovski, M; Hadzi-Petrushev, N; Kamkin, A; Mitrokhin, V; Mladenov, M1
Abraham-Fan, RJ; Lindner, JR; López, JA; Muller, M; Ozawa, K; Packwood, W; Varlamov, O; Wu, MD; Xie, A1
Barbosa, RAQ; Carvalho, AB; Costa, CRM; Fortunato, RS; Olivares, EL; Peixoto, MS; Ramos, IP; Seara, FAC; Silveira, ALB1
Huang, CH; Jiang, SJ1
Lehnen, TE; Lima, A; Maia, AL; Santos, MV; Wajner, SM1
Abdalla, IL; Kaooh, S; Mohamed, EA; Sadik, AOE; Zaki, SM1
Lim, GB1
Açar, B; Akboğa, MK; Demirtaş, K; Ünal, S; Yayla, Ç; Yayla, KG1
Hausenloy, DJ; Yellon, DM1
Boyle, AJ; Khan, AA1
Auffret, V; Le Breton, H; Mansour, A1
Li, L; Su, Q; Ye, Z1
Beltrame, JF; Pasupathy, S; Tavella, R1
Fei, Q; Liu, K; Liu, M; Wang, H; Wang, K; Wang, N; Xiao, H; Xiao, X; Zhang, H; Zou, J1
Ibanez, B; Lobo-Gonzalez, M; Rossello, X1
Bell, SP; Chen, Z; Christian, TF; Dauerman, HL; Gibson, PC; Keating, FF; Lachapelle, RR; LeWinter, MM; Meyer, M; Nyotowidjojo, I1
Chang, NC; Lee, TM; Lin, SZ1
Broumand, MA; Darabi, F; Jenab, Y; Khalili, H; Salarifar, M; Talasaz, AH1
Broumand, MA; Darabi, F; Fahimi, F; Jenab, Y; Khalili, H; Salarifar, M; Talasaz, AH1
Lacampagne, A; Roubille, F1
Baotic, I; Bienengraeber, M; Bosnjak, ZJ; Kersten, JR; Lazar, J; Muravyeva, M; Sedlic, F; Warltier, DC1
Christiansen, EH; Hansen, HS; Hansen, KN; Jensen, LO; Jensen, SE; Junker, A; Lassen, JF; Ravkilde, J; Thayssen, P; Thuesen, L; Veien, KT1
Larsen, PR; Leite, RS; Maia, AL; Manica, A; Schaan, BD; Vidart, J; Wajner, SM1
Chen, H; Guo, Y; Li, L; Li, N; Liu, R; Wang, L; Xia, Y; Yin, Y; Zhai, H; Zhang, J1
Bonomo, C; Cezar, MD; Damatto, RL; Fernandes, DC; Guizoni, DM; Junior, SA; Laurindo, FR; Lima, AR; Martinez, PF; Matsubara, LS; Novelli, EL; Okoshi, K; Okoshi, MP; Pagan, LU; Seiva, FR; Zornoff, LA1
Andrades, M; Biolo, A; Clausell, N; Cohen, C; Dal-Pizzol, F; Lopes, A; Martinelli, N; Olsen, V; Phaelante, A; Rohde, LE; Tobar, SA1
Irwin, MG; Li, H; Li, Y; Lin, J; Wang, M; Wang, T; Xia, Z1
Caffrey, JL; Downey, HF; Estrada, JA; Gonzalez, L; Mallet, RT; Sun, J; Williams, AG1
Bonomo, C; Bueno, RT; Cezar, MD; Damatto, RL; Fernandes, DC; Guizoni, DM; Junior, SA; Laurindo, FR; Lima, AR; Martinez, PF; Okoshi, K; Okoshi, MP; Pagan, LU; Seiva, FR; Zornoff, LA1
Abe, M; Ichimaru, S; Kaji, S; Takiguchi, Y; Tsuchiya, K; Wada, K1
Boontje, NM; de Crom, R; de Waard, MC; Dekkers, DH; Duncker, DJ; Kuster, DW; Lamers, JM; van der Velden, J; van Haperen, R1
Bell, SP; Chen, Z; Dauerman, HL; LeWinter, MM; Meyer, M; Selby, DE; Singla, DK1
Fischell, TA1
Chang, NC; Lai, PY; Lee, TM1
Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Grotti, S; Liistro, F; Limbruno, U; Picchi, A; Pierli, C1
McCarty, MF1
Adams, V; Desch, S; Diederich, KW; Eitel, I; Erbs, S; Fuernau, G; Gutberlet, M; Hildebrand, L; Linke, A; Nowak, M; Schirdewahn, C; Schuler, G; Thiele, H1
Brar, S; Dangas, G; Mehran, R1
Beckman, S; Drowley, L; Huard, J; Keller, B; Okada, M; Tobita, K; Vella, J1
Sochman, J2
Chun, DH; Hong, SW; Kim, JC; Kwak, YL; Shim, JK; Yoo, KJ1
Fujita, M; Hirai, T; Miki, K; Suzuki, N; Suzuki, Y; Tanaka, A; Tanaka, T; Yasuda, N1
Basha, RH; Priscilla, DH1
Adams, V; Blase, P; Desch, S; Droppa, M; Eitel, I; Fuernau, G; Schuler, G; Thiele, H1
Irwin, MG; Lam, KS; Lei, S; Liu, Y; Ng, KF; Qiao, S; Wang, T; Xia, Z; Xu, A1
Khanna, AK; Mehra, MR; Xu, J1
Hidhayath Basha, R; Nagoor Meeran, MF; Stanely Mainzen Prince, P1
Akdeniz, C; Aslanger, E; Cizgici, Y; Oflaz, H; Polat, N; Uslu, B1
Nagoor Meeran, MF; Stanely Mainzen Prince, P1
Aurelio, A; Basile, E; Buffon, A; Burzotta, F; Crea, F; De Caterina, AR; Leone, AM; Lioy, E; Mazzari, MA; Mongiardo, R; Niccoli, G; Panocchia, N; Porto, I; Rebuzzi, AG; Romagnoli, E; Sciahbasi, A; Trani, C1
Jankowski, J; Statz, M; Tepel, M; van der Giet, M; Zidek, W1
Di Napoli, M; Papa, F1
Kehl, F; Kersten, JR; Krolikowski, JG; Pagel, PS; Warltier, DC; Weihrauch, D1
Luo, YT; Xiao, X; Xiong, AH; Yan, QC1
Bai, A; Calvillo, L; De Angelis, N; Fiordaliso, F; Ghezzi, P; Latini, R; Masson, S; Pollicino, L; Salio, M; Santangelo, F1
Cordan, J; Sağ, S; Senturk, T; Serdar, A; Serdar, Z; Yesilbursa, D1
Das, DK; Das, S; Engelman, RM; Maulik, N1
Assanelli, E; Bartorelli, AL; Campodonico, J; De Metrio, M; Fabbiocchi, F; Galli, S; Grazi, M; Lauri, G; Marana, I; Marenzi, G; Montorsi, P; Veglia, F1
Ritz, E1
Cafri, C; Wolak, A; Zahger, D1
Balderramo, DC1
Losano, G; Mancardi, D; Pagliaro, P; Penna, C; Rastaldo, R1
Moss, NC; Selzman, CH; Stansfield, WE; Tang, R; Willis, MS1
Adamy, C; Andrieu-abadie, N; Berdeaux, A; Candiani, G; Caramelle, P; Damy, T; Defer, N; Hittinger, L; Khouzami, L; Kirsch, M; Le Corvoisier, P; Levade, T; Mulder, P; Pavoine, C; Pecker, F; Perier, M; Souktani, R; Thuillez, C1
Fujioka, D; Kawabata, K; Kitta, Y; Kobayashi, T; Kodama, Y; Kugiyama, K; Nakamura, T; Obata, JE; Saito, Y; Takano, H; Yano, T1
Cagiano, R; Cazzato, A; Colantuono, G; D'Agostino, D; Di Venosa, N; Federici, A; Fiore, T; Rastaldo, R; Tiravanti, EA1
Capasso, R; De Santo, NG; Ingrosso, D; Lombardi, C; Luciano, MG; Perna, AF; Pulzella, P; Satta, E1
Diwan, V; Jaggi, AS; Khanna, G; Singh, M; Singh, N1
Fu, J; Li, H; Li, W; Li, Y; Liu, B; Liu, P; Wang, Z1
Arstall, MA; Betts, WH; Horowitz, JD; Stafford, I; Yang, J1
Musilová, B; Rocek, M; Sochman, J; Vrbská, J2
Simon, K; Szépvölgyi, A1
Hegde, BM; Tripathi, Y1
Kempa, M; Minczykowski, A; Sajkowska, A; Szczepanik, A; Wykretowicz, A; Wysocki, H1
Buikema, H; Crijns, HJ; de Zeeuw, D; Monnink, SH; Tio, RA; van Gilst, WH1
Alam, J; Das, DK; Ho, YS; Maulik, N; Yoshida, T1
Rozanski, GJ; Xu, Z1
Bender, W; Schmidt, EW2
Peregrin, JH; Sochman, J1
Alberola, A; Gil, F; Morcillo, EJ; Such, L; Zaragoza, R1
Horowitz, JD1
Kolc, J; Sochman, J; Vrána, M1
Fabián, J; Kolc, J; Sochman, J; Vrána, M2
Kingma, JG; Rouleau, JR1
Antman, EM; Fish, RD; Henry, CA; Horowitz, JD; Louis, WJ; Smith, TW; Syrjanen, ML1
Beckman, JK; Cates, CU; Forman, MB; Greene, HL; McCroskey, DE; Puett, DW; Virmani, R1
Alberola, A; Aparicio, F; Chorro, FJ; Montoro, A; Morcillo, E; Such, L; Viña, J1

Reviews

9 review(s) available for acetylcysteine and Cardiovascular Stroke

ArticleYear
Joint Cardioprotective Effect of Vitamin C and Other Antioxidants against Reperfusion Injury in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention.
    Molecules (Basel, Switzerland), 2021, Sep-21, Volume: 26, Issue:18

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Biomarkers; Deferoxamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Male; Myocardial Infarction; Oxidative Stress; Percutaneous Coronary Intervention; Polyphenols; Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Stroke Volume; Tocopherols; Ventricular Function, Left

2021
Myocardial infarction and oxidative damage in animal models: objective and expectations from the application of cysteine derivatives.
    Toxicology mechanisms and methods, 2023, Volume: 33, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Glutathione; Motivation; Myocardial Infarction; Oxidative Stress

2023
The Clinical Efficacy of N-Acetylcysteine in the Treatment of ST Segment Elevation Myocardial Infarction.
    International heart journal, 2021, Jan-30, Volume: 62, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Creatine Kinase, MB Form; Female; Free Radical Scavengers; Heart Failure; Humans; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Randomized Controlled Trials as Topic; ST Elevation Myocardial Infarction; Stroke Volume; Treatment Outcome; Troponin T

2021
Pharmacotherapy: NAC plus nitrate therapy in PCI.
    Nature reviews. Cardiology, 2017, Volume: 14, Issue:8

    Topics: Acetylcysteine; Drug Therapy, Combination; Humans; Myocardial Infarction; Nitroglycerin; Percutaneous Coronary Intervention; Postoperative Complications; Preoperative Care; Vasodilator Agents

2017
Editor's Choice- Pathophysiology and therapy of myocardial ischaemia/reperfusion syndrome.
    European heart journal. Acute cardiovascular care, 2019, Volume: 8, Issue:5

    Topics: Acetylcysteine; Acute Disease; Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; Animals; Cardiotonic Agents; Exenatide; Free Radical Scavengers; Humans; Hypoglycemic Agents; Incidence; Metoprolol; Mice; Mice, Transgenic; Microcirculation; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Percutaneous Coronary Intervention; Randomized Controlled Trials as Topic; ST Elevation Myocardial Infarction

2019
Practical prevention of cardiac remodeling and atrial fibrillation with full-spectrum antioxidant therapy and ancillary strategies.
    Medical hypotheses, 2010, Volume: 75, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Atrial Fibrillation; Fibrosis; Heart Failure; Humans; Mitochondria; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Superoxides

2010
MLN-519. Millennium/PAION.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:3

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cysteine Endopeptidases; Enzyme Inhibitors; Humans; Inflammation; Multienzyme Complexes; Myocardial Infarction; Neuroprotective Agents; Proteasome Endopeptidase Complex; Stroke; Ubiquitin

2003
N-acetylcysteine in acute cardiology: 10 years later: what do we know and what would we like to know?!
    Journal of the American College of Cardiology, 2002, May-01, Volume: 39, Issue:9

    Topics: Acetylcysteine; Cardiology; Clinical Trials as Topic; Free Radical Scavengers; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Oxidative Stress; Reactive Oxygen Species; Ventricular Function, Left

2002
Thiol-containing agents in the management of unstable angina pectoris and acute myocardial infarction.
    The American journal of medicine, 1991, Sep-30, Volume: 91, Issue:3C

    Topics: Acetylcysteine; Angina, Unstable; Drug Therapy, Combination; Humans; Myocardial Infarction; Nitroglycerin; Platelet Aggregation; Sulfhydryl Compounds

1991

Trials

18 trial(s) available for acetylcysteine and Cardiovascular Stroke

ArticleYear
N-Acetylcysteine effects on transforming growth factor-β and tumor necrosis factor-α serum levels as pro-fibrotic and inflammatory biomarkers in patients following ST-segment elevation myocardial infarction.
    Drugs in R&D, 2013, Volume: 13, Issue:3

    Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Aged, 80 and over; Biomarkers; Double-Blind Method; Drug Therapy, Combination; Echocardiography; Electrocardiography; Female; Fibrosis; Humans; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Transforming Growth Factor beta; Treatment Outcome; Tumor Necrosis Factor-alpha

2013
Effects of N-acetylcysteine on the cardiac remodeling biomarkers and major adverse events following acute myocardial infarction: a randomized clinical trial.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antioxidants; Biomarkers; Double-Blind Method; Female; Follow-Up Studies; Hospitalization; Humans; Length of Stay; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Myocardial Infarction; Prospective Studies; Secondary Prevention; Treatment Outcome; Ventricular Remodeling

2014
Prevention of contrast-induced nephropathy with N-acetylcysteine or sodium bicarbonate in patients with ST-segment-myocardial infarction: a prospective, randomized, open-labeled trial.
    Circulation. Cardiovascular interventions, 2014, Volume: 7, Issue:2

    Topics: Acetylcysteine; Aged; Contrast Media; Creatinine; Drug Therapy, Combination; Electrocardiography; Female; Humans; Incidence; Infusions, Intravenous; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Percutaneous Coronary Intervention; Prospective Studies; Sodium Bicarbonate; Treatment Outcome

2014
N-acetylcysteine administration prevents nonthyroidal illness syndrome in patients with acute myocardial infarction: a randomized clinical trial.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:12

    Topics: Acetylcysteine; Acute Disease; Acute-Phase Reaction; Adult; Aged; Antioxidants; Female; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Infarction; Pituitary Gland; Prospective Studies; Thyroid Gland; Thyroid Hormones; Treatment Outcome

2014
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Heart Diseases; Humans; Iohexol; Italy; Myocardial Infarction; Prospective Studies; Research Design; Single-Blind Method; Syndrome; Time Factors; Treatment Outcome; Triiodobenzoic Acids

2010
Impact of high-dose N-acetylcysteine versus placebo on contrast-induced nephropathy and myocardial reperfusion injury in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The LIPSIA-
    Journal of the American College of Cardiology, 2010, May-18, Volume: 55, Issue:20

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Creatinine; Female; Free Radical Scavengers; Humans; Logistic Models; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Oxidative Stress; Prospective Studies; Single-Blind Method; Treatment Outcome

2010
Effect of N-acetylcysteine on pulmonary function in patients undergoing off-pump coronary artery bypass surgery.
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:4

    Topics: Acetylcysteine; Acute Lung Injury; Aged; Blood Loss, Surgical; Blood Transfusion; Coronary Artery Bypass, Off-Pump; Creatine Kinase; Double-Blind Method; Female; Free Radical Scavengers; Hemodynamics; Humans; Lung; Male; Middle Aged; Myocardial Infarction; Postoperative Complications; Pulmonary Circulation; Respiratory Function Tests; Vascular Resistance; Ventricular Dysfunction, Left; Water-Electrolyte Balance

2011
Does N-acetylcysteine reduce the incidence of contrast-induced nephropathy and clinical events in patients undergoing primary angioplasty for acute myocardial infarction?
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:7

    Topics: Acetylcysteine; Administration, Oral; Aged; Angioplasty; Contrast Media; Creatinine; Female; Free Radical Scavengers; Hospital Mortality; Humans; Incidence; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Treatment Outcome

2011
Impact of N-acetylcysteine on contrast-induced nephropathy defined by cystatin C in patients with ST-elevation myocardial infarction undergoing primary angioplasty.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2011, Volume: 100, Issue:11

    Topics: Acetylcysteine; Aged; Angioplasty, Balloon, Coronary; Biomarkers; Chi-Square Distribution; Contrast Media; Cystatin C; Female; Germany; Heart Failure; Humans; Kidney Diseases; Logistic Models; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Radiography; Recurrence; Risk Assessment; Risk Factors; Single-Blind Method; Time Factors; Treatment Outcome; Up-Regulation

2011
Intrarenal application of N-acetylcysteine for the prevention of contrast medium-induced nephropathy in primary angioplasty.
    Coronary artery disease, 2012, Volume: 23, Issue:4

    Topics: Acetylcysteine; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Humans; Injections, Intra-Arterial; Injections, Intravenous; Ioxaglic Acid; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Renal Artery; Treatment Outcome

2012
The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure: a randomized, controlled trial.
    Circulation, 2003, Feb-25, Volume: 107, Issue:7

    Topics: Acetylcysteine; Antioxidants; Cardiovascular Diseases; Endpoint Determination; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Renal Dialysis; Survival Analysis; Treatment Outcome

2003
Effect of N-acetylcysteine on oxidative stress and ventricular function in patients with myocardial infarction.
    Heart and vessels, 2006, Volume: 21, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Biomarkers; Creatine Kinase, MB Form; Drug Therapy, Combination; Echocardiography, Doppler; Female; Fibrinolytic Agents; Free Radical Scavengers; Humans; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Nitroglycerin; Oxidative Stress; Research Design; Streptokinase; Stroke Volume; Treatment Outcome; Vasodilator Agents; Ventricular Function, Left; Ventricular Remodeling

2006
N-acetylcysteine and contrast-induced nephropathy in primary angioplasty.
    The New England journal of medicine, 2006, Jun-29, Volume: 354, Issue:26

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Creatinine; Female; Humans; Kidney Diseases; Logistic Models; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction

2006
N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction. Safety and biochemical effects.
    Circulation, 1995, Nov-15, Volume: 92, Issue:10

    Topics: Acetylcysteine; Cardiac Catheterization; Drug Synergism; Drug Therapy, Combination; Female; Fibrinolytic Agents; Free Radical Scavengers; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Nitroglycerin; Oxidative Stress; Streptokinase; Time Factors; Vasodilator Agents

1995
Infarct size limitation: acute N-acetylcysteine defense (ISLAND) trial. Start of the study.
    International journal of cardiology, 1995, Volume: 49, Issue:2

    Topics: Acetylcysteine; Coronary Angiography; Echocardiography; Electrocardiography; Humans; Myocardial Infarction; Pilot Projects; Streptokinase; Stroke Volume; Thrombolytic Therapy; Ventricular Function, Left

1995
Infarct Size Limitation: acute N-acetylcysteine defense (ISLAND trial): preliminary analysis and report after the first 30 patients.
    Clinical cardiology, 1996, Volume: 19, Issue:2

    Topics: Acetylcysteine; Aged; Creatine Kinase; Drug Therapy, Combination; Electrocardiography; Fibrinolytic Agents; Free Radical Scavengers; Humans; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Pilot Projects; Streptokinase; Stroke Volume; Thrombolytic Therapy; Ventricular Function, Left

1996
Fibrinolytic therapy and n-acetylocysteine in the treatment of patients with acute myocardial infarction: its influence on authentic plasma hydroperoxide levels and polymorphonuclear neutrophil oxygen metabolism.
    Cardiology, 1999, Volume: 91, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Drug Therapy, Combination; Female; Humans; Hydrogen Peroxide; Lipid Peroxides; Male; Middle Aged; Myocardial Infarction; Neutrophils; Oxidative Stress; Oxygen Consumption; Streptokinase; Thrombolytic Therapy

1999
Combined use of nitroglycerin and N-acetylcysteine in the management of unstable angina pectoris.
    Circulation, 1988, Volume: 77, Issue:4

    Topics: Acetylcysteine; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypotension; Male; Myocardial Infarction; Nitroglycerin; Random Allocation; Risk Factors

1988

Other Studies

66 other study(ies) available for acetylcysteine and Cardiovascular Stroke

ArticleYear
d-Limonene Ameliorates Myocardial Infarction Injury by Reducing Reactive Oxygen Species and Cell Apoptosis in a Murine Model.
    Journal of natural products, 2019, 11-22, Volume: 82, Issue:11

    Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Electrocardiography; Limonene; Long QT Syndrome; Male; Mice; Molecular Structure; Myocardial Infarction; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase

2019
Elevated LDL Cholesterol Increases Microvascular Endothelial VWF and Thromboinflammation After Myocardial Infarction.
    Arteriosclerosis, thrombosis, and vascular biology, 2023, Volume: 43, Issue:6

    Topics: Acetylcysteine; ADAMTS13 Protein; Animals; Cholesterol, LDL; Inflammation; Ischemia; Mice; Myocardial Infarction; Thromboinflammation; von Willebrand Factor

2023
Progression of heart failure is attenuated by antioxidant therapy with N-acetylcysteine in myocardial infarcted female rats.
    Molecular biology reports, 2020, Volume: 47, Issue:11

    Topics: Acetylcysteine; Animals; Antioxidants; Electrocardiography; Female; Heart; Myocardial Infarction; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species

2020
N-Acetylcysteine Prevents Low T3 Syndrome and Attenuates Cardiac Dysfunction in a Male Rat Model of Myocardial Infarction.
    Endocrinology, 2017, 05-01, Volume: 158, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Disease Models, Animal; Euthyroid Sick Syndromes; Male; Myocardial Infarction; Myocytes, Cardiac; Protein Carbonylation; Rats; Rats, Wistar; Thyroid Hormones; Ventricular Dysfunction

2017
Protective Role of N-Acetylcysteine on Isoprenaline-Induced Myocardial Injury: Histological, Immunohistochemical and Morphometric Study.
    Cardiovascular toxicology, 2018, Volume: 18, Issue:1

    Topics: Acetylcysteine; Actins; Animals; Collagen; Cytoprotection; Disease Models, Animal; Immunohistochemistry; Isoproterenol; Male; Myocardial Infarction; Myocytes, Cardiac; Proliferating Cell Nuclear Antigen; Rats, Wistar; Time Factors

2018
N-Acetylcysteine and Contrast-Induced Nephropathy.
    Angiology, 2018, Volume: 69, Issue:1

    Topics: Acetylcysteine; Blood Platelets; Humans; Kidney Diseases; Lymphocytes; Myocardial Infarction; Percutaneous Coronary Intervention

2018
Combination Therapy to Target Reperfusion Injury After ST-Segment-Elevation Myocardial Infarction: A More Effective Approach to Cardioprotection.
    Circulation, 2017, 09-05, Volume: 136, Issue:10

    Topics: Acetylcysteine; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Reperfusion Injury; ST Elevation Myocardial Infarction

2017
Letter by Khan and Boyle Regarding Article, "Early Use of N-Acetylcysteine (NAC) With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct Size (The NAC
    Circulation, 2018, 03-27, Volume: 137, Issue:13

    Topics: Acetylcysteine; Humans; Myocardial Infarction; Nitrates; Percutaneous Coronary Intervention; ST Elevation Myocardial Infarction

2018
Letter by Mansour et al Regarding Article, "Early Use of N-Acetylcysteine With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment-Elevation Myocardial Infarction Reduces Myocardial Infarct Size (the NACIAM Tri
    Circulation, 2018, 03-27, Volume: 137, Issue:13

    Topics: Acetylcysteine; Humans; Myocardial Infarction; Nitrates; Percutaneous Coronary Intervention; ST Elevation Myocardial Infarction

2018
Letter by Ye et al Regarding Article, "Early Use of
    Circulation, 2018, 03-27, Volume: 137, Issue:13

    Topics: Acetylcysteine; Humans; Myocardial Infarction; Nitrates; Percutaneous Coronary Intervention; ST Elevation Myocardial Infarction

2018
Response by Pasupathy et al to Letters Regarding Article, "Early Use of N-acetylcysteine (NAC) With Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct
    Circulation, 2018, 03-27, Volume: 137, Issue:13

    Topics: Acetylcysteine; Humans; Myocardial Infarction; Nitrates; Percutaneous Coronary Intervention; ST Elevation Myocardial Infarction

2018
VEGF-A promotes angiogenesis after acute myocardial infarction through increasing ROS production and enhancing ER stress-mediated autophagy.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Acetylcysteine; Animals; Autophagy; Beclin-1; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Myocardial Infarction; Myocardial Ischemia; Neovascularization, Physiologic; Reactive Oxygen Species; RNA, Small Interfering; Vascular Endothelial Growth Factor A

2019
High dose intracoronary N-acetylcysteine in a porcine model of ST-elevation myocardial infarction.
    Journal of thrombosis and thrombolysis, 2013, Volume: 36, Issue:4

    Topics: Acetylcysteine; Animals; Contrast Media; Coronary Angiography; Disease Models, Animal; Female; Free Radical Scavengers; Iopamidol; Myocardial Infarction; Myocardial Reperfusion Injury; Swine

2013
Both PKA and Epac pathways mediate N-acetylcysteine-induced Connexin43 preservation in rats with myocardial infarction.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Brefeldin A; Cardiotonic Agents; Connexin 43; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Evaluation, Preclinical; Free Radical Scavengers; Gap Junctions; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Isoquinolines; Male; Myocardial Infarction; Permeability; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Sulfonamides; Ventricular Remodeling

2013
New drug avenues for cardioprotection in patients with acute myocardial infarction.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2014, Volume: 14, Issue:1

    Topics: Acetylcysteine; Antioxidants; Female; Humans; Male; Myocardial Infarction; Ventricular Remodeling

2014
Cardioprotection during diabetes: the role of mitochondrial DNA.
    Anesthesiology, 2014, Volume: 120, Issue:4

    Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA, Mitochondrial; Free Radical Scavengers; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Wistar; Reactive Oxygen Species

2014
Aging increases the susceptivity of MSCs to reactive oxygen species and impairs their therapeutic potency for myocardial infarction.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Acetylcysteine; Aging; Animals; Apoptosis; Cell Adhesion; Free Radical Scavengers; Heart; Hydrogen Peroxide; Integrins; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Myocardial Infarction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2014
Influence of N- acetylcysteine on oxidative stress in slow-twitch soleus muscle of heart failure rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:1

    Topics: Acetylcysteine; Animals; Ethidium; Free Radical Scavengers; Glutathione Peroxidase; Heart Failure; Heart Ventricles; Male; Malondialdehyde; Muscle, Skeletal; Myocardial Infarction; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine

2015
N-acetylcysteine Plus Deferoxamine Improves Cardiac Function in Wistar Rats After Non-reperfused Acute Myocardial Infarction.
    Journal of cardiovascular translational research, 2015, Volume: 8, Issue:5

    Topics: Acetylcysteine; Aldehydes; Animals; Antioxidants; Deferoxamine; Echocardiography; Immunohistochemistry; Iron; Iron Chelating Agents; Male; Myocardial Infarction; Myocardium; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Stroke Volume; Sulfhydryl Compounds; Troponin I; Ventricular Function

2015
N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Acetylcysteine; Adiponectin; Animals; Antioxidants; CD36 Antigens; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Transcription Factors; Male; Methyl Ethers; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nerve Tissue Proteins; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; Sevoflurane; STAT3 Transcription Factor; Time Factors; Troponin I

2016
δ-Opioid receptor (DOR) signaling and reactive oxygen species (ROS) mediate intermittent hypoxia induced protection of canine myocardium.
    Basic research in cardiology, 2016, Volume: 111, Issue:2

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Dogs; Female; Hematocrit; Hypoxia; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardium; Naltrexone; Reactive Oxygen Species; Receptors, Opioid, delta

2016
Modulation of MAPK and NF-954;B Signaling Pathways by Antioxidant Therapy in Skeletal Muscle of Heart Failure Rats.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Blotting, Western; Echocardiography; Gene Expression; Heart Failure; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Myocardial Infarction; MyoD Protein; Myogenin; NF-kappa B; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Ventricular Dysfunction, Left

2016
Different effect of acute treatment with rosiglitazone on rat myocardial ischemia/reperfusion injury by administration method.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Acetylcysteine; Animals; Antioxidants; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; I-kappa B Proteins; Infusions, Intravenous; Injections, Intravenous; Male; Models, Biological; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Peroxidase; Phosphorylation; PPAR gamma; Protective Agents; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha

2008
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Exercise Therapy; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Physical Exertion; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Time Factors; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Pressure; Ventricular Remodeling

2009
N-acetylcysteine-enhanced contrast provides cardiorenal protection.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:3

    Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Contrast Media; Creatinine; Disease Models, Animal; Feasibility Studies; Free Radical Scavengers; Iopamidol; Kidney; Kidney Diseases; Myocardial Infarction; Myocardium; Risk Factors; Swine

2009
Contrast loaded with N-acetylcysteine for coronary imaging during percutaneous coronary intervention: a new concept for renal and myocardial protection during percutaneous coronary intervention.
    JACC. Cardiovascular interventions, 2009, Volume: 2, Issue:3

    Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Contrast Media; Disease Models, Animal; Free Radical Scavengers; Iopamidol; Kidney; Kidney Diseases; Myocardial Infarction; Myocardium

2009
Effect of N-acetylcysteine on sympathetic hyperinnervation in post-infarcted rat hearts.
    Cardiovascular research, 2010, Jan-01, Volume: 85, Issue:1

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Buthionine Sulfoximine; Echocardiography; Fluorescent Antibody Technique; Glutathione; Heart; Male; Myocardial Infarction; Nerve Growth Factor; Norepinephrine; Rats; Rats, Wistar; Sympathetic Nervous System

2010
Contrast-induced acute kidney injury. Underappreciated or a new marker of cardiovascular mortality?
    Journal of the American College of Cardiology, 2010, May-18, Volume: 55, Issue:20

    Topics: Acetylcysteine; Acute Kidney Injury; Contrast Media; Free Radical Scavengers; Humans; Myocardial Infarction; Oxidative Stress

2010
Cellular antioxidant levels influence muscle stem cell therapy.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2010, Volume: 18, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Differentiation; Cell Proliferation; Cell Survival; Cell- and Tissue-Based Therapy; Cells, Cultured; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Male; Maleates; Mice; Mice, Inbred C57BL; Mice, SCID; Muscle, Skeletal; Myocardial Infarction; Platelet Endothelial Cell Adhesion Molecule-1; Stem Cells; Vascular Endothelial Growth Factor A

2010
N-acetylcysteine somewhere between Scylla and Charybdis.
    Journal of the American College of Cardiology, 2010, Sep-21, Volume: 56, Issue:13

    Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Contrast Media; Free Radical Scavengers; Humans; Kidney Diseases; Myocardial Infarction; Randomized Controlled Trials as Topic; Reperfusion Injury

2010
An in vivo and in vitro study on the protective effects of N-acetylcysteine on mitochondrial dysfunction in isoproterenol treated myocardial infarcted rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:1-2

    Topics: Acetylcysteine; Animals; Antioxidants; Creatine Kinase; Data Interpretation, Statistical; Disease Models, Animal; In Vitro Techniques; Isoproterenol; Lipid Peroxidation; Male; Microscopy, Electron, Transmission; Mitochondria, Heart; Mitochondrial Diseases; Myocardial Infarction; Rats; Rats, Wistar

2013
N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Acetylcysteine; Adiponectin; Allopurinol; Animals; Antioxidants; Biomarkers; Blood Glucose; Creatine Kinase, MB Form; Diabetes Complications; Dinoprost; Drug Synergism; Gene Expression Regulation; Hemodynamics; Interleukin-6; Isoprostanes; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Signal Transduction; Tumor Necrosis Factor-alpha

2011
Antioxidant N-acetyl cysteine reverses cigarette smoke-induced myocardial infarction by inhibiting inflammation and oxidative stress in a rat model.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Base Sequence; Cotinine; Cytokines; Disease Models, Animal; DNA Primers; Echocardiography; Inflammation; Myocardial Infarction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Smoke

2012
Preventive effects of N-acetyl cysteine on lipids, lipoproteins and myocardial infarct size in isoproterenol induced myocardial infarcted rats: an in vivo and in vitro study.
    European journal of pharmacology, 2012, Feb-29, Volume: 677, Issue:1-3

    Topics: Acetylcysteine; Animals; Biomarkers; Free Radical Scavengers; Isoproterenol; Lipoproteins; Liver; Male; Myocardial Infarction; Rats; Rats, Wistar

2012
Protective effects of N-acetyl cysteine on membrane-bound adenosine triphosphatases and minerals in isoproterenol-induced myocardial-infarcted rats: an in vivo and in vitro study.
    Journal of biochemical and molecular toxicology, 2012, Volume: 26, Issue:7

    Topics: Acetylcysteine; Adenosine Triphosphatases; Animals; Cardiotonic Agents; Cell Membrane; Enzyme Activation; Isoproterenol; Lipid Peroxidation; Male; Membrane Proteins; Minerals; Molecular Targeted Therapy; Myocardial Infarction; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

2012
Sodium bicarbonate plus N-acetylcysteine to prevent contrast-induced nephropathy in primary and rescue percutaneous coronary interventions: the BINARIO (BIcarbonato e N-Acetil-cisteina nell'infaRto mIocardico acutO) study.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2012, Nov-22, Volume: 8, Issue:7

    Topics: Acetylcysteine; Aged; Contrast Media; Female; Fluid Therapy; Hospital Mortality; Humans; Italy; Kidney Diseases; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Percutaneous Coronary Intervention; Prospective Studies; Registries; Renal Dialysis; Retrospective Studies; Risk Factors; Sodium Bicarbonate; Time Factors; Treatment Outcome

2012
N-acetylcysteine restores isoflurane-induced preconditioning against myocardial infarction during hyperglycemia.
    Anesthesiology, 2003, Volume: 98, Issue:6

    Topics: Acetylcysteine; Anesthetics, Inhalation; Animals; Collateral Circulation; Coronary Circulation; Dogs; Female; Free Radical Scavengers; Hemodynamics; Hyperglycemia; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction; Myocardium; Ventricular Function, Left

2003
[Significance of plasma 8-iso-prostaglandin F2alpha level in acute myocardial ischemia and intervention effect of N-acetylcysteine: a study in rats].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:6

    Topics: Acetylcysteine; Animals; Dinoprost; Electrocardiography; F2-Isoprostanes; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar

2003
In vivo cardioprotection by N-acetylcysteine and isosorbide 5-mononitrate in a rat model of ischemia-reperfusion.
    Cardiovascular drugs and therapy, 2003, Volume: 17, Issue:3

    Topics: Acetylcysteine; Animals; Blood Pressure; Drug Therapy, Combination; Free Radical Scavengers; Isosorbide Dinitrate; Male; Monocytes; Myocardial Infarction; Myocardial Reperfusion Injury; Neutrophils; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley

2003
Angiotensin preconditioning of the heart: evidence for redox signaling.
    Cell biochemistry and biophysics, 2006, Volume: 44, Issue:1

    Topics: Acetophenones; Acetylcysteine; Angiotensin II; Animals; Antioxidants; Apoptosis; Gene Expression; Heart; Heart Rate; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Membrane Glycoproteins; Membrane Transport Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidation-Reduction; Perfusion; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling

2006
N-acetylcysteine and contrast-induced nephropathy.
    The New England journal of medicine, 2006, Oct-05, Volume: 355, Issue:14

    Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Creatinine; Cystatin C; Cystatins; Glomerular Filtration Rate; Humans; Kidney Diseases; Myocardial Infarction

2006
N-acetylcysteine and contrast-induced nephropathy.
    The New England journal of medicine, 2006, Oct-05, Volume: 355, Issue:14

    Topics: Acetylcysteine; Angioplasty, Balloon, Coronary; Contrast Media; Hospitals, Teaching; Humans; Kidney Diseases; Myocardial Infarction; Renal Replacement Therapy

2006
N-acetylcysteine and contrast-induced nephropathy.
    The New England journal of medicine, 2006, Oct-05, Volume: 355, Issue:14

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Contrast Media; Dose-Response Relationship, Drug; Hospital Mortality; Humans; Kidney Diseases; Myocardial Infarction

2006
Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling.
    Cardiovascular research, 2007, Jul-01, Volume: 75, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Decanoic Acids; Hydroxy Acids; Mitochondria, Heart; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Bradykinin B2; Signal Transduction

2007
Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury.
    The Annals of thoracic surgery, 2007, Volume: 84, Issue:1

    Topics: Acetylcysteine; Animals; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; NF-kappa B; Proteasome Inhibitors

2007
Neutral sphingomyelinase inhibition participates to the benefits of N-acetylcysteine treatment in post-myocardial infarction failing heart rats.
    Journal of molecular and cellular cardiology, 2007, Volume: 43, Issue:3

    Topics: Acetylcysteine; Animals; Cardiotonic Agents; Case-Control Studies; Disease Models, Animal; Echocardiography, Doppler; Glutathione; Heart Failure; Male; Myocardial Infarction; Oxidative Stress; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sphingomyelin Phosphodiesterase; Time Factors; Tumor Necrosis Factor-alpha

2007
Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Acetylcysteine; Adiponectin; Administration, Oral; Animals; Animals, Newborn; Antioxidants; Blood Glucose; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids; Glucose; Hydrogen Peroxide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Insulin; Insulin Resistance; Ligation; Lipids; Male; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Oxidation-Reduction; Pravastatin; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Recombinant Proteins; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Tumor Necrosis Factor-alpha

2007
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:1

    Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Animal; Free Radical Scavengers; Glyburide; Heart Rate; Hydroxy Acids; Hypoxia; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Respiration, Artificial; Time Factors; Ventricular Function, Left; Ventricular Pressure

2008
Is homocysteine toxic in uremia?
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2008, Volume: 18, Issue:1

    Topics: Acetylcysteine; Antitoxins; Cardiovascular Diseases; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Myocardial Infarction; Recurrence; Reference Values; Renal Dialysis; Retrospective Studies; Risk Factors; Uremia

2008
Reduction of ischemic, pharmacological and remote preconditioning effects by an antioxidant N-acetyl cysteine pretreatment in isolated rat heart.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2008, Volume: 128, Issue:3

    Topics: Acetylcysteine; Angiotensin II; Animals; Cardiotonic Agents; Female; Free Radical Scavengers; Hydrogen Peroxide; In Vitro Techniques; Ischemic Preconditioning; Male; Myocardial Infarction; Oxidation-Reduction; Rats; Rats, Wistar; Reactive Oxygen Species

2008
Protective effects of N-acetylcysteine in isoproterenol-induced myocardium injury in rats.
    Molecular biology reports, 2009, Volume: 36, Issue:4

    Topics: Acetylcysteine; Animals; Creatine Kinase, MB Form; Cytokines; Gene Expression Regulation; Isoproterenol; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Rats; Rats, Wistar

2009
N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction: safety and biochemical effects.
    Circulation, 1996, Oct-01, Volume: 94, Issue:7

    Topics: Acetylcysteine; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; Humans; Myocardial Infarction; Nitroglycerin; Streptokinase; Vasodilator Agents

1996
Effect of N-acetylcysteine on myocardial infarct size following ischemia and reperfusion in dogs.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:1

    Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Vessels; Dogs; Free Radical Scavengers; Glutathione; Lipid Peroxidation; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Superoxide Dismutase

1998
Comparison of zofenopril and lisinopril to study the role of the sulfhydryl-group in improvement of endothelial dysfunction with ACE-inhibitors in experimental heart failure.
    British journal of pharmacology, 2000, Volume: 130, Issue:8

    Topics: Acetylcholine; Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Calcimycin; Captopril; Endothelium, Vascular; Heart Diseases; In Vitro Techniques; Lisinopril; Male; Myocardial Infarction; Nitrates; Nitrites; Nitroglycerin; omega-N-Methylarginine; Rats; Rats, Wistar; Sodium Nitrite; Sulfhydryl Compounds; Vasodilation; Vasodilator Agents

2000
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 gene.
    Circulation, 2001, Mar-27, Volume: 103, Issue:12

    Topics: Acetylcysteine; Animals; Antioxidants; Chromans; Creatine Kinase; Disease Models, Animal; Gene Targeting; Heart; Heart Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Heterozygote; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Malondialdehyde; Membrane Proteins; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Reperfusion Injury; Thiourea

2001
Glutathione and K(+) channel remodeling in postinfarction rat heart.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6

    Topics: Acetylcysteine; Animals; Colorimetry; Electric Conductivity; Electrophysiology; Glucose; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; Male; Myocardial Infarction; NADP; Oxidative Stress; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Time Factors; Ventricular Function

2002
[Sensitivity of creatine kinase and creatine kinase MB in myocardial infarction. Evaluation of a new optimized standard method (author's transl)].
    Medizinische Klinik, 1979, Mar-16, Volume: 74, Issue:11

    Topics: Acetylcysteine; Creatine Kinase; Humans; Isoenzymes; Myocardial Infarction

1979
[Creatine kinase and creatine kinase isoenzyme MB: determination of normal values and values for myocardial infarct, using the new, optimized method with N-acetyl cysteine as the activator (author's transl)].
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1979, Volume: 17, Issue:1

    Topics: Acetylcysteine; Creatine Kinase; Enzyme Activation; Glutathione; Humans; Isoenzymes; Kinetics; Myocardial Infarction

1979
Total recovery of left ventricular function after acute myocardial infarction: comprehensive therapy with streptokinase, N-acetylcysteine and percutaneous transluminal coronary angioplasty.
    International journal of cardiology, 1992, Volume: 35, Issue:1

    Topics: Acetylcysteine; Adult; Angioplasty, Balloon, Coronary; Drug Therapy, Combination; Humans; Male; Myocardial Infarction; Streptokinase; Ventricular Function, Left

1992
Protective effect of N-acetylcysteine on ischaemia-induced myocardial damage in canine heart.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:5

    Topics: Acetylcysteine; Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Female; Glutathione; Male; Myocardial Infarction; Time Factors

1991
[Possibilities of limiting myocardial infarct in an experiment].
    Casopis lekaru ceskych, 1991, Feb-01, Volume: 130, Issue:5

    Topics: Acetylcysteine; Animals; Dogs; Female; Male; Myocardial Infarction; Myocardium

1991
[N-acetylcysteine: its effect on myocardial infarct in dogs].
    Ceskoslovenska fysiologie, 1990, Volume: 39, Issue:6

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Dogs; Electrocardiography; Female; Heart Rate; Male; Myocardial Infarction; Myocardium

1990
Cardioprotective effects of N-acetylcysteine: the reduction in the extent of infarction and occurrence of reperfusion arrhythmias in the dog.
    International journal of cardiology, 1990, Volume: 28, Issue:2

    Topics: Acetylcysteine; Animals; Arrhythmias, Cardiac; Dogs; Electrocardiography; Female; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Time Factors

1990
Effect of N-acetylcysteine on tissue necrosis during acute myocardial infarction in rabbits.
    The Canadian journal of cardiology, 1989, Volume: 5, Issue:6

    Topics: Acetylcysteine; Animals; Free Radicals; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Rabbits

1989
Glutathione redox pathway and reperfusion injury. Effect of N-acetylcysteine on infarct size and ventricular function.
    Circulation, 1988, Volume: 78, Issue:1

    Topics: Acetylcysteine; Animals; Coronary Circulation; Dogs; Female; Glutathione Peroxidase; Heart; Heart Ventricles; Hemodynamics; Male; Myocardial Infarction; Oxidation-Reduction

1988
Beneficial effects of N-acetyl cysteine on acute myocardial infarction in open-chest dogs.
    Archivos de farmacologia y toxicologia, 1986, Volume: 12, Issue:1

    Topics: Acetylcysteine; Animals; Coronary Circulation; Dogs; Female; Hemodynamics; Male; Myocardial Infarction

1986