Compounds > acetylcysteine

acetylcysteine and Cardiomyopathy, Hypertrophic Obstructive

acetylcysteine has been researched along with Cardiomyopathy, Hypertrophic Obstructive in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Lopes, LR; Maltês, S1
Bluemke, DA; Chang, J; Cheong, BY; Hessabi, M; Kleiman, NS; Li, L; Liu, CY; Marian, AJ; Nagueh, SF; Rahbar, MH; Syrris, P; Tan, Y; Willerson, JT1
Basrur, V; Day, SM; Gestwicki, JE; Glazier, AA; Hafeez, N; Helms, AS; Lee, LM; Mellacheruvu, D; Nesvizhskii, AI; Shao, H; Tang, V; Yob, JM1
Betocchi, S; Chen, J; Chen, SN; Efimov, IR; Li, W; Lombardi, R; Marian, AJ; Ripplinger, CM; Rodriguez, G; Wickline, SA; Willerson, JT1
Chen, SN; Lombardi, R; Marian, AJ; Senthil, V1

Reviews

1 review(s) available for acetylcysteine and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
New perspectives in the pharmacological treatment of hypertrophic cardiomyopathy.
    Revista portuguesa de cardiologia, 2020, Volume: 39, Issue:2

    Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cardiovascular Agents; Diltiazem; Genetic Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocytes, Cardiac; Sodium Channel Blockers

2020

Trials

1 trial(s) available for acetylcysteine and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Hypertrophy Regression With N-Acetylcysteine in Hypertrophic Cardiomyopathy (HALT-HCM): A Randomized, Placebo-Controlled, Double-Blind Pilot Study.
    Circulation research, 2018, 04-13, Volume: 122, Issue:8

    Topics: Acetylcysteine; Adult; Aged; Antioxidants; Cardiomyopathy, Hypertrophic; Connectin; Double-Blind Method; Echocardiography, Doppler; Exome; Female; Fibrosis; Heart; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardium; Pilot Projects; Polymorphism, Single Nucleotide

2018

Other Studies

3 other study(ies) available for acetylcysteine and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
HSC70 is a chaperone for wild-type and mutant cardiac myosin binding protein C.
    JCI insight, 2018, 06-07, Volume: 3, Issue:11

    Topics: Acetylcysteine; Animals; Animals, Newborn; Cardiomyopathy, Hypertrophic; Carrier Proteins; Cell Nucleus; Gene Knockdown Techniques; Haploinsufficiency; HEK293 Cells; HSC70 Heat-Shock Proteins; Humans; Myocardium; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Proteostasis; Rats; Sarcomeres; Ventricular Septum

2018
Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms.
    Circulation, 2009, Mar-17, Volume: 119, Issue:10

    Topics: Acetylcysteine; Actins; Animals; Animals, Genetically Modified; Antioxidants; Cardiomyopathy, Hypertrophic; Cell Size; Disease Models, Animal; Female; Fibrosis; Glutathione; Heart Failure, Systolic; Humans; Male; MAP Kinase Signaling System; Myocytes, Cardiac; Myosin Heavy Chains; NFATC Transcription Factors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Rabbits; Sulfhydryl Compounds; Ventricular Fibrillation

2009
Antifibrotic effects of antioxidant N-acetylcysteine in a mouse model of human hypertrophic cardiomyopathy mutation.
    Journal of the American College of Cardiology, 2006, Feb-21, Volume: 47, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cardiomyopathy, Hypertrophic; Collagen; DNA; DNA, Mitochondrial; Echocardiography; Fibrosis; Gene Expression; Heart; Lipid Peroxidation; Malondialdehyde; Matrix Metalloproteinase 1; Mice; Mice, Transgenic; Myocardium; Procollagen; Reverse Transcriptase Polymerase Chain Reaction

2006