Compounds > acetylcysteine

acetylcysteine and Cardiomyopathies

acetylcysteine has been researched along with Cardiomyopathies in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's2 (8.33)18.2507
2000's3 (12.50)29.6817
2010's13 (54.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirata, Y; Isagawa, T; Kido, Y; Komuro, I; Manabe, I; Nakagama, Y; Okamura, K; Ono, M; Sakamoto, M; Sato, T; Soma, K; Takeda, N1
Ahlberg, G; Collins, MM; El-Sammak, H; Guenther, S; Hansen, CV; Hellsten, Y; Lundegaard, PR; Marín-Juez, R; Olesen, MS; Piesker, J; Sokol, AM; Stainier, DYR1
Cheng, Z; Feng, X; Gao, E; Hu, J; Lin, J; Sun, D; Wang, H; Wang, S; Wang, T; Zhang, M1
Arica, S; Arica, V; Basarslan, F; Demir, İH; Karcoıglu, M; Nacar, A; Öztürk, H; Tutanc, M1
Berzingi, C; Chen, F; Finkel, MS; Hadfield, JM; Hollander, JM; Miller, DB; Nichols, CE1
Bailleux, V; Batonnet-Pichon, S; Briki, F; Delort, F; Gausseres, B; Leccia, E; Segard, BD; Simon, S; Vicart, P1
Alavi, H; Asri-Rezaee, S; Farshid, AA; Mansouri, S; Najafi, S; Simaee, N; Tamaddonfard, E1
Akkoc, H; Akkus, M; Kelle, I; Topal, AE; Topal, D; Yilmaz, S1
Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Khamseekaew, J; Kumfu, S; Srichairatanakool, S; Sripetchwandee, J; Wongjaikam, S1
Abdel-Qadir, H; Amir, E; Fazelzad, R; Lee, DS; Ong, G; Thavendiranathan, P; Tomlinson, G1
Akita, Y; Iwasaka, T; Matsuhisa, S; Moriguchi, A; Okazaki, T; Otani, H; Sato, D; Yamashita, K1
Hueckstaedt, LK; Li, Q; Ren, J1
Dalic, A; Dart, AM; Drummond, G; Du, XJ; Fang, L; Gao, XM; Kiriazis, H; Ritchie, RH; Sarwar, M; Sim, K; Xu, Q; Zhang, YY1
Arunachalam, S; Hwang, PH; Kim, MS; Kim, SY; Lee, SH; Lee, YH; Yi, HK; Yun, BS1
Baseler, W; Chen, F; Finkel, MS; Hollander, JM; Lewis, W1
Crespo, MJ; Escobales, N1
Bonow, R; Corden, B; Doroshow, J; Epstein, S; Jenkins, J; Locker, G; Myers, C; Palmeri, S1
Balcerzak, SP; Jagadeesh, JM; Leier, CV; Magorien, RD; Unverferth, BJ; Unverferth, DV1
Hamlin, RL; Leier, CV; Mehegan, JP; Nelson, RW; Scott, CC; Unverferth, DV1
Balcerzak, SP; Leier, CV; Magorien, RD; Unverferth, BJ; Unverferth, DV1
Barr, LH; Bonow, RO; d'Angelo, T; Dresdale, AR; Mathisen, DJ; Myers, CE; Rosenberg, SA; Schwartz, DE1
Finkel, MS; Oddis, CV; Romeo, RC; Salama, G; Shen, L1
Favalli, L; Galimberti, M; Lanza, E; Monti, E; Piccinini, F; Poggi, P; Rozza, A; Villani, F; Zunino, F1
Baldini, L; Candussio, L; Decorti, G; Grill, V; Klugmann, FB; Mallardi, F1

Reviews

1 review(s) available for acetylcysteine and Cardiomyopathies

ArticleYear
Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, 03-01, Volume: 28, Issue:3

    Topics: Acetylcysteine; Adrenergic beta-Antagonists; Angiotensins; Anthracyclines; Cardiomyopathies; Clinical Trials as Topic; Dexrazoxane; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neoplasms; Network Meta-Analysis; Prenylamine; Ventricular Dysfunction, Left

2017

Trials

3 trial(s) available for acetylcysteine and Cardiomyopathies

ArticleYear
A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine.
    Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Cardiomyopathies; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Patient Compliance; Random Allocation; Stroke Volume

1983
Attempt to prevent doxorubicin-induced acute human myocardial morphologic damage with acetylcysteine.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:5

    Topics: Acetylcysteine; Adult; Aged; Biopsy; Cardiomyopathies; Doxorubicin; Drug Evaluation; Endocardium; Humans; Microscopy, Electron; Middle Aged; Mitochondria, Heart; Myocardium

1983
Prospective randomized study of the role of N-acetyl cysteine in reversing doxorubicin-induced cardiomyopathy.
    American journal of clinical oncology, 1982, Volume: 5, Issue:6

    Topics: Acetylcysteine; Adolescent; Adult; Cardiomyopathies; Child; Doxorubicin; Female; Heart Function Tests; Humans; Male; Middle Aged; Prospective Studies; Random Allocation; Sarcoma; Soft Tissue Neoplasms

1982

Other Studies

20 other study(ies) available for acetylcysteine and Cardiomyopathies

ArticleYear
Therapeutic targeting of mitochondrial ROS ameliorates murine model of volume overload cardiomyopathy.
    Journal of pharmacological sciences, 2019, Volume: 141, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Cardiomyopathies; Disease Models, Animal; Heart Failure; Male; Mice, Inbred C57BL; Mitochondria; Molecular Targeted Therapy; Myocytes, Cardiac; Reactive Oxygen Species

2019
Early sarcomere and metabolic defects in a zebrafish
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 11-26, Volume: 116, Issue:48

    Topics: Acetylcysteine; Animals; Animals, Genetically Modified; Antioxidants; Arrhythmias, Cardiac; Cardiac Conduction System Disease; Cardiomyopathies; Disease Models, Animal; Electrocardiography; Gene Expression Regulation; Homeodomain Proteins; Larva; Mitochondria, Heart; Sarcomeres; Stress, Physiological; Transcription Factors; Zebrafish; Zebrafish Proteins

2019
Cardiac-specific Mst1 deficiency inhibits ROS-mediated JNK signalling to alleviate Ang II-induced cardiomyocyte apoptosis.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:1

    Topics: Acetylcysteine; Angiotensin II; Animals; Apoptosis; Cardiomyopathies; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Signal Transduction; Thioredoxins

2019
N-acetylcysteine prevents doxorubucine-induced cardiotoxicity in rats.
    Human & experimental toxicology, 2013, Volume: 32, Issue:6

    Topics: Acetylcysteine; Animals; Cardiomyopathies; Doxorubicin; Free Radical Scavengers; Nitric Oxide; Rats; Thiobarbituric Acid Reactive Substances; Topoisomerase II Inhibitors

2013
N-acetylcysteine reverses cardiac myocyte dysfunction in a rodent model of behavioral stress.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Aug-15, Volume: 115, Issue:4

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Cardiomyopathies; Catalase; Disease Models, Animal; Epinephrine; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Isoproterenol; Male; Myocardium; Myocytes, Cardiac; Norepinephrine; Oxidative Stress; Rats; Rats, Sprague-Dawley

2013
N-acetyl-L-cysteine prevents stress-induced desmin aggregation in cellular models of desminopathy.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Acetylcysteine; Animals; Cardiomyopathies; Cell Line; Codon; Cytoskeleton; Desmin; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Expression; Heat-Shock Proteins; Humans; Mice; Muscular Dystrophies; Mutation; Protein Binding; Stress, Physiological

2013
Effects of histidine and N-acetylcysteine on doxorubicin-induced cardiomyopathy in rats.
    Cardiovascular toxicology, 2014, Volume: 14, Issue:2

    Topics: Acetylcysteine; Animals; Biomarkers; Cardiomyopathies; Creatine Kinase; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Drug Therapy, Combination; Electrocardiography; Free Radical Scavengers; Heart Rate; Histidine; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardium; Rats, Wistar; Recovery of Function

2014
Impact of N-acetylcysteine and etodolac treatment on systolic and diastolic function in a rat model of myocardial steatosis induced by high-fat-diet.
    Endocrine, metabolic & immune disorders drug targets, 2014, Volume: 14, Issue:4

    Topics: Acetylcysteine; Animals; Cardiomyopathies; Diastole; Diet, High-Fat; Disease Models, Animal; Etodolac; Lipid Metabolism Disorders; Male; Rats; Rats, Sprague-Dawley; Systole

2014
Combined Iron Chelator and Antioxidant Exerted Greater Efficacy on Cardioprotection Than Monotherapy in Iron-Overloaded Rats.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Acetylcysteine; Animals; Benzoates; Cardiomyopathies; Cardiotonic Agents; Deferasirox; Deferiprone; Deferoxamine; Drug Combinations; Drug Synergism; Humans; Iron; Iron Chelating Agents; Iron Overload; Iron, Dietary; Male; Malondialdehyde; Mitochondria; Pyridones; Rats; Rats, Wistar; Triazoles; Ventricular Function, Left

2016
N-acetylcysteine abolishes the protective effect of losartan against left ventricular remodeling in cardiomyopathy hamster.
    Antioxidants & redox signaling, 2008, Volume: 10, Issue:12

    Topics: Acetylcysteine; Amidines; Angiotensin II Type 1 Receptor Blockers; Animals; Benzylamines; Cardiomyopathies; Cricetinae; Drug Interactions; Enzyme Inhibitors; Fibrosis; Free Radical Scavengers; Heart; Heart Ventricles; Losartan; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Ventricular Function, Left; Ventricular Remodeling

2008
The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase.
    Experimental physiology, 2009, Volume: 94, Issue:9

    Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Calcium-Binding Proteins; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; High-Temperature Requirement A Serine Peptidase 2; In Vitro Techniques; Male; MAP Kinase Signaling System; Mice; Mitochondrial Proteins; Myocardial Contraction; Myocytes, Cardiac; Protease Inhibitors; Pyrimidinones; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine Endopeptidases; Stilbenes; Streptozocin; Thiones; X-Linked Inhibitor of Apoptosis Protein

2009
Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure.
    British journal of pharmacology, 2011, Volume: 162, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Cardiomyopathies; Collagen; Cytokines; Disease Models, Animal; Heart Failure; HSP27 Heat-Shock Proteins; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Reactive Oxygen Species; Receptors, Adrenergic, beta-2; RNA, Messenger; Signal Transduction; Ventricular Remodeling

2011
Davallialactone protects against adriamycin-induced cardiotoxicity in vitro and in vivo.
    Journal of natural medicines, 2012, Volume: 66, Issue:1

    Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Blotting, Western; Cardiomyopathies; Caspase 3; Cell Line; Cell Survival; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; JNK Mitogen-Activated Protein Kinases; Lactones; Male; Mice; Mice, Inbred BALB C; Myocytes, Cardiac; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Reactive Oxygen Species; Superoxide Dismutase; Time Factors

2012
N-acetylcysteine reverses cardiac myocyte dysfunction in HIV-Tat proteinopathy.
    Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 113, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antiviral Agents; Calcium; Cardiomyopathies; Catalase; Female; Gene Products, tat; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; HIV Infections; Hydrogen Peroxide; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Oxidative Stress

2012
Angiotensin II-dependent vascular alterations in young cardiomyopathic hamsters: role for oxidative stress.
    Vascular pharmacology, 2006, Volume: 44, Issue:1

    Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Blood Pressure; Cardiomyopathies; Cricetinae; Disease Models, Animal; Losartan; Male; Mesocricetus; NADPH Oxidases; Oxidative Stress; Superoxides

2006
The efficacy of N-acetylcysteine in preventing doxorubicin-induced cardiomyopathy in dogs.
    Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1

    Topics: Acetylcysteine; Animals; Antioxidants; Blood Pressure; Cardiac Catheterization; Cardiomyopathies; Dogs; Doxorubicin; Drug Interactions; Echocardiography; Heart Rate; Heart Ventricles; Systole

1983
Early changes in human myocardial nuclei after doxorubicin.
    Cancer, 1983, Jul-15, Volume: 52, Issue:2

    Topics: Acetylcysteine; Cardiomyopathies; Cell Nucleolus; Cell Nucleus; Chronic Disease; Dose-Response Relationship, Drug; Doxorubicin; Heart; Humans; Myocardium

1983
Positive inotropic effect of acetylcysteine in cardiomyopathic Syrian hamsters.
    Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:1

    Topics: Acetylcysteine; Analysis of Variance; Animals; Cardiomyopathies; Cricetinae; Cysteine; Cystine; Male; Mesocricetus; Myocardial Contraction; Papillary Muscles; Ryanodine; Stimulation, Chemical; Verapamil

1993
Effect of glutathione and N-acetylcysteine on in vitro and in vivo cardiac toxicity of doxorubicin.
    Free radical research communications, 1990, Volume: 11, Issue:1-3

    Topics: Acetylcysteine; Animals; Cardiomyopathies; Doxorubicin; Female; Glutathione; Heart Atria; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1990
Inhibitors of adriamycin-induced histamine release in vitro limit adriamycin cardiotoxicity in vivo.
    British journal of cancer, 1986, Volume: 54, Issue:5

    Topics: Acetylcysteine; Animals; Cardiomyopathies; Cromolyn Sodium; Dose-Response Relationship, Drug; Doxorubicin; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Theophylline

1986