acetylcysteine has been researched along with Cancer of Head in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 8 (32.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blanchard, MJ; Foote, RL; Gamez, ME; Garces, YI; Grover, Y; Halyard, MY; Martenson, JA; McGee, LA; Miller, RC; Neben Wittich, MA; Novotny, PJ; Patel, SH; Pederson, LD; Rwigema, JM; Seeger, GR; Sio, TT | 1 |
| Baek, SK; Chung, PS; Kim, JH; Koo, BS; Kwon, SY; Lee, DW; Lee, GH; Lee, SH; Lee, SJ; Park, IS; Ryu, CH; Shin, SC; Won, HR | 1 |
| Bottelin, M; François, C; Galmiche, A; Godin, C; Hémon, A; Lailler, C; Louandre, C; Morel, V; Saidak, Z | 1 |
| Buettner, GR; Goswami, PC; Kalen, AL; Lafin, JT; Sarsour, EH; Wagner, BA | 1 |
| Altemani, JMC; Amaral, LS; Calonga, L; Chone, CT; Curi, SFBB; de F L Ambrósio, R; de Sousa, VM; de T Leme, MF; Lima, CSP; Malaguti, C; Mazzola, PG; Moriel, P; Quintanilha, JCF; Vercesi, AE; Visacri, MB | 1 |
| Angel, D; Franklin, J; Fung, K; Hamilton, SJ; Lewis, D; Parnes, LS; Venkatesan, V; Winquist, E; Yoo, J | 1 |
| Kim, EH; Kim, JW; Kwon, M; Lee, BH; Park, JY; Roh, JL | 1 |
| Ahmad, IM; Aykin-Burns, N; Dayal, D; Dornfeld, KJ; Li, L; Mattson, DM; Orcutt, KP; Parsons, AD; Simons, AL; Spitz, DR | 1 |
| Rosenthal, DI; Trotti, A | 1 |
| Hwang, HS; Kang, SU; Kim, CH; Kim, YS; Lee, BS; Lim, YC; Shin, YS; Sung, ES | 1 |
| Hebert, C; Nikitakis, NG; Norris, K; Sauk, JJ; Siavash, H; Stewart, J | 1 |
| Bockmühl, U; Fuchs, J; Gross, J; Jahnke, V; Kietzmann, T; Machulik, A | 1 |
| Cho, HR; Choi, DH; Chung, DK; Kim, JS; Kim, SB; Ko, MS; Kwon, BS; Lee, BJ; Lee, DS; Lee, HW; Lee, JH; Park, JW; Yoon, WJ | 1 |
| Ahmad, IM; Dornfeld, KJ; Mattson, DM; Simons, AL; Spitz, DR | 1 |
| Desai, KG; Mallery, SR; Schwendeman, SP | 1 |
| Goepfert, H; Hong, WK; Hsu, TC; Lee, JJ; Schantz, SP; Spitz, MR; Trizna, Z | 1 |
| Baak, JP; Beliën, JA; Braakhuis, BJ; Copper, MP; Snow, GB | 1 |
| de Vries, N; Pastorino, U; van Zandwijk, N | 4 |
| Bairati, I; Brochet, F; Gélinas, M; Mâsse, B; Meyer, F; Nabid, A; Roy, J; Têtu, B | 1 |
| Bongers, V; Braakhuis, BJ; Cloos, J; Lubsen, H; Snow, GB; Tobi, H | 1 |
| Dalesio, O; de Vries, N; Pastorino, U; van Tinteren, H; van Zandwijk, N | 1 |
| Hsu, TC; Schantz, SP; Trizna, Z | 1 |
3 review(s) available for acetylcysteine and Cancer of Head
| Article | Year |
|---|---|
Strategies for managing radiation-induced mucositis in head and neck cancer.
Topics: Acetylcysteine; Amifostine; Carcinoma, Squamous Cell; Glutamine; Head and Neck Neoplasms; Humans; Intercellular Signaling Peptides and Proteins; Low-Level Light Therapy; Mouthwashes; Oral Hygiene; Pain Management; Risk Factors; Stomatitis | 2009 |
[Prevention of second primary cancer with vitamin supplementation in patients treated for head and neck cancers].
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; beta Carotene; Carcinoma, Squamous Cell; Carotenoids; Follow-Up Studies; Head and Neck Neoplasms; Humans; Neoplasm Staging; Neoplasms, Second Primary; Risk Factors; Vegetables; Vitamin A; Vitamin E; Vitamins | 1996 |
Chemoprevention in the management of oral cancer: EUROSCAN and other studies.
Topics: Acetylcysteine; Antineoplastic Agents; Carcinoma, Squamous Cell; Diterpenes; Europe; Head and Neck Neoplasms; Humans; Mouth Neoplasms; Neoplasms, Second Primary; Research Design; Retinyl Esters; Risk Factors; Vitamin A | 1992 |
8 trial(s) available for acetylcysteine and Cancer of Head
| Article | Year |
|---|---|
N-Acetylcysteine Rinse for Thick Secretion and Mucositis of Head and Neck Chemoradiotherapy (Alliance MC13C2): A Double-Blind Randomized Clinical Trial.
Topics: Acetylcysteine; Aged; Chemoradiotherapy; Double-Blind Method; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mouth Mucosa; Mouthwashes; Mucositis; Patient Reported Outcome Measures; Patient Safety; Pilot Projects; Prospective Studies; Quality of Life; Reference Values; Risk Assessment; Treatment Outcome; Xerostomia | 2019 |
Can acetylcysteine ameliorate cisplatin-induced toxicities and oxidative stress without decreasing antitumor efficacy? A randomized, double-blind, placebo-controlled trial involving patients with head and neck cancer.
Topics: Acetylcysteine; Administration, Oral; Aged; Chemoradiotherapy; Cisplatin; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Oxidative Stress; Treatment Outcome | 2019 |
Cisplatin otoprotection using transtympanic L-N-acetylcysteine: a pilot randomized study in head and neck cancer patients.
Topics: Acetylcysteine; Adult; Audiometry; Auditory Threshold; Cisplatin; Feasibility Studies; Female; Follow-Up Studies; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Humans; Injections, Intralesional; Male; Middle Aged; Prospective Studies; Reference Values; Risk Assessment; Treatment Outcome; Tympanic Membrane | 2014 |
Chemoprevention of second primary tumours in head and neck cancer in Europe: EUROSCAN.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Cricetinae; Diterpenes; Europe; Female; Head and Neck Neoplasms; Humans; Male; Mice; Neoplasms, Second Primary; Rats; Rats, Sprague-Dawley; Retinyl Esters; Vitamin A | 1994 |
Chemoprevention of cancer.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Diet; Digestive System Neoplasms; Diterpenes; Head and Neck Neoplasms; Humans; Isotretinoin; Lung Neoplasms; Neoplasms, Second Primary; Retinyl Esters; Smoking Prevention; Vitamin A | 1993 |
Lack of effect of daily N-acetylcysteine supplementation on mutagen sensitivity.
Topics: Acetylcysteine; Adult; Aged; Analysis of Variance; Anticarcinogenic Agents; Antioxidants; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Middle Aged; Mutagenesis; Mutagenicity Tests; Neoplasms, Second Primary | 1996 |
EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer. For the EUropean Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Diterpenes; Drug Administration Schedule; Europe; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms, Second Primary; Patient Compliance; Retinyl Esters; Risk Factors; Smoking; Survival Analysis; Treatment Failure; Vitamin A | 2000 |
The EUROSCAN Study. EUROSCAN Steering Committee.
Topics: Acetylcysteine; Head and Neck Neoplasms; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Survival Analysis; Vitamin A | 1991 |
14 other study(ies) available for acetylcysteine and Cancer of Head
| Article | Year |
|---|---|
Effects of N-acetylcysteine inhalation therapy on the quality of life of patients with head and neck cancer who are receiving radiation therapy: a prospective non-randomized controlled multi-center study.
Topics: Acetylcysteine; Aged; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Radiation Injuries; Respiratory Therapy; Stomatitis | 2021 |
SLC7A11 as a biomarker and therapeutic target in HPV-positive head and neck Squamous Cell Carcinoma.
Topics: Acetylcysteine; Amino Acid Transport System y+; Biological Transport, Active; Biomarkers; Cell Line, Tumor; Cystine; Ferroptosis; Gene Expression Regulation, Neoplastic; Glutathione; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Repressor Proteins; RNA-Seq; Single-Cell Analysis; Squamous Cell Carcinoma of Head and Neck | 2020 |
Methylseleninic Acid Induces Lipid Peroxidation and Radiation Sensitivity in Head and Neck Cancer Cells.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Gamma Rays; Glutathione; Head and Neck Neoplasms; Humans; Lipid Peroxidation; Organoselenium Compounds; Oxygen Consumption; Radiation Tolerance; Time Factors | 2019 |
Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Dioxolanes; Drug Synergism; Free Radical Scavengers; Glutathione S-Transferase pi; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oxidative Stress; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2014 |
Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism.
Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Therapy, Combination; Glutathione; Head and Neck Neoplasms; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Sulfhydryl Compounds; Zidovudine | 2009 |
An agonistic antibody to human death receptor 4 induces apoptotic cell death in head and neck cancer cells through mitochondrial ROS generation.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Apoptosis; bcl-X Protein; Cell Line, Tumor; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred BALB C; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; X-Linked Inhibitor of Apoptosis Protein; Zebrafish | 2012 |
Phenotypic switching of VEGF and collagen XVIII during hypoxia in head and neck squamous carcinoma cells.
Topics: Acetylcysteine; Androstadienes; Antimutagenic Agents; Biomarkers; Cell Hypoxia; Cell Line, Tumor; Cobalt; Collagen Type XVIII; Enzyme Inhibitors; Head and Neck Neoplasms; Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Humans; Imidazoles; MAP Kinase Signaling System; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Phosphodiesterase Inhibitors; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Vascular Endothelial Growth Factor A; Wortmannin | 2003 |
Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.
Topics: Acetylcysteine; Apoptosis; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Cell Nucleus; Cell Shape; Cobalt; Deferoxamine; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Necrosis; Nuclear Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors | 2005 |
NF-kappaB activation is required for cisplatin-induced apoptosis in head and neck squamous carcinoma cells.
Topics: Acetylcysteine; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Autocrine Communication; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Cysteine Proteinase Inhibitors; Head and Neck Neoplasms; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Signal Transduction; Thiocarbamates; Tumor Necrosis Factor-alpha | 2006 |
2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells.
Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Catalase; Cell Growth Processes; Cisplatin; Deoxyglucose; Drug Synergism; Glutathione; Head and Neck Neoplasms; Humans; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase | 2007 |
Formulation and characterization of injectable poly(DL-lactide-co-glycolide) implants loaded with N-acetylcysteine, a MMP inhibitor.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Calcium Compounds; Calorimetry, Differential Scanning; Catalysis; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Implants; Drug Stability; Head and Neck Neoplasms; Humans; Injections; Kinetics; Lactic Acid; Magnesium Compounds; Matrix Metalloproteinase Inhibitors; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protease Inhibitors; Solubility; Technology, Pharmaceutical; X-Ray Diffraction | 2008 |
In vitro protective effects of chemopreventive agents against bleomycin-induced genotoxicity in lymphoblastoid cell lines and peripheral blood lymphocytes of head and neck cancer patients.
Topics: Acetylcysteine; Anticarcinogenic Agents; Antimutagenic Agents; Ascorbic Acid; Bleomycin; Cell Line; Chromosome Aberrations; Head and Neck Neoplasms; Humans; Lymphocytes; Tretinoin; Vitamin E | 1993 |
Standardization of counting micronuclei: definition of a protocol to measure genotoxic damage in human exfoliated cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Cell Count; Cells, Cultured; Confidence Intervals; Gamma Rays; Head and Neck Neoplasms; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mouth Mucosa; Mouth Neoplasms; Mutagenicity Tests; Mutagens; Observer Variation; Patient Selection; Recurrence; Regression Analysis; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; Vitamin A | 1995 |
Effects of N-acetyl-L-cysteine and ascorbic acid on mutagen-induced chromosomal sensitivity in patients with head and neck cancers.
Topics: Acetylcysteine; Ascorbic Acid; Bleomycin; Cell Line; Chromosome Fragility; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Humans; In Vitro Techniques; Lymphocytes; Tumor Cells, Cultured | 1991 |