acetylcysteine has been researched along with Brain Neoplasms in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 16 (50.00) | 29.6817 |
| 2010's | 11 (34.38) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, F; Ji, Y; Li, H; Lu, Y; Qiu, P; Tang, H; Zhang, S | 1 |
| Li, F; Li, W; Song, D; Zhu, Y | 1 |
| Luo, Y; Pengfei, G; Wang, H; Zhang, J; Zhang, S; Zhong, J | 1 |
| Kayama, T; Kitanaka, C; Narita, Y; Okada, M; Sato, A; Seino, S; Shibui, S; Shibuya, K; Watanabe, E | 1 |
| Muldoon, LL; Neuwelt, EA; Pagel, MA; Wu, YJ | 1 |
| Hu, L; Jiang, ZC; Li, HX; Li, LL; Lin, ZG; Yang, KB; Zhao, SG | 1 |
| Chi, SG; Chung, YG; Kang, SH; Park, DH; Park, KJ; Yu, MO | 1 |
| Carpinelli, G; Castigli, E; Conte, C; Degrassi, F; Di Bari, M; Fiore, M; Iorio, E; Ricordy, R; Sciaccaluga, M; Tata, AM; Tombolillo, V | 1 |
| Chi, G; Ge, P; Lu, B; Luo, T; Luo, Y; Ma, H; Wang, C; Zheng, L; Zhou, Z; Zhu, D | 1 |
| Burant, CF; Davis, M; Dresser, J; Feng, FY; Kachman, M; Lawrence, TS; Lyssiotis, CA; Morgan, MA; Parsels, JD; Speers, C; Wahl, DR; Wernisch, S; Wilder-Romans, K; Zhao, L; Zhao, SG | 1 |
| Basu, A; Duseja, R; Ghosh, D; Mishra, MK | 1 |
| Andreazza, AC; Braganhol, E; de Souza, DO; Gonçalves, CA; Nardin, P; Quincozes-Santos, A; Tortorelli, L; Tramontina, AC; Wartchow, KM | 1 |
| Gao, H; Gao, R; Khan, M; Li, T; Ma, T; Rasul, A; Wang, N; Yi, F | 1 |
| Hashimoto, K; Iyo, M; Komatsu, N; Shimizu, E | 1 |
| Chang, WM; Huang, KL; Lai, MT; Lai, YK | 1 |
| Brannon, J; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Lebedeva, IV; Linehan, WM; McKinstry, R; Mitchell, C; Qiao, L; Rosenberg, E; Sarkar, D; Su, ZS; Valerie, K; Yacoub, A | 1 |
| Broaddus, WC; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Lebedeva, IV; Lister, A; McKinstry, R; Mitchell, C; Qiao, L; Ramakrishnan, V; Sarkar, D; Sigmon, C; Su, ZZ; Yacoub, A | 1 |
| Kraemer, DF; Muldoon, LL; Neuwelt, EA; Pagel, MA; Peterson, DR | 1 |
| Friedlander, M; Kurtovic, J; Riordan, SM; Singh-Grewal, I; Webster, GJ | 1 |
| Broaddus, WC; Curiel, DT; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Gupta, P; Hong, Y; James, CD; Lebedeva, IV; Mahasreshti, PJ; Mitchell, C; Rosenfeld, MR; Sauane, M; Su, ZZ; Yacoub, A | 1 |
| Eugster, HP; Frei, K; Ishihara, H; Könü, D; Kubota, H; Möhler, H; Rodak, R; Yonekawa, Y | 1 |
| Brem, H; DiMeco, F; Fiorindi, A; Gaini, SM; Legnani, FG; Olivi, A; Pradilla, G; Recinos, PF; Thai, QA; Tyler, BM | 1 |
| Robbins, ME; Smith, PS; Spitz, DR; Zhao, W | 1 |
| Antolín, I; García-Santos, G; Herrera, F; Martín, V; Rodriguez, C; Rodriguez-Blanco, J | 1 |
| Colica, C; Costa, N; Mollace, V; Muscoli, C; Palma, E; Rotiroti, D; Sacco, I; Sculco, F; Visalli, V | 1 |
| García-Escudero, V; Gargini, R; Izquierdo, M | 1 |
| Alvarez-Sala, R; Caballero, P; García Río, F; Pino, JM; Prados, C; Villamor, J | 1 |
| Hori, K; Ishii, K; Katayama, M; Sato, N; Waga, S; Yodoi, J | 1 |
| Blaivas, M; Kish, P; Muraszko, KM; Ross, DA; Strawderman, M | 1 |
| Ikemoto, H; Kitagawa, H; Matsumoto, T; Tani, E | 1 |
| Deloughery, TG; Hasler, BP; Muldoon, LL; Neuwelt, EA; Pagel, MA | 1 |
| Lungarotti, R; Pauli, P | 1 |
32 other study(ies) available for acetylcysteine and Brain Neoplasms
| Article | Year |
|---|---|
A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Free Radical Scavengers; Glioblastoma; Humans; Melanthiaceae; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Rhizome; Saponins; Signal Transduction; Temozolomide | 2020 |
RETRACTED: Physcion 8-O-β-glucopyranosideregulates cell cycle, apoptosis, and invasion in glioblastoma cells through modulating Skp2.
Topics: Acetylcysteine; Adenylate Kinase; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Emodin; Glioblastoma; Glucosides; Humans; Reactive Oxygen Species; S-Phase Kinase-Associated Proteins; TOR Serine-Threonine Kinases | 2017 |
The proteasome inhibitor lactacystin exerts its therapeutic effects on glioma via apoptosis: an in vitro and in vivo study.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Glioma; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Proteasome Inhibitors; Rats; RNA, Messenger; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Buthionine Sulfoximine; Cell Differentiation; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glioma; Humans; Hydrogen Peroxide; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 7; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; RNA Interference; Transplantation, Heterologous | 2014 |
N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Brain Neoplasms; Cells, Cultured; Child; Cisplatin; Disease Models, Animal; Female; Humans; Male; Medulloblastoma; Neoplasm Transplantation; Neoplasms, Experimental; Neuroblastoma; Oxidative Stress; Rats; Rats, Nude | 2015 |
Blockage of potassium channel inhibits proliferation of glioma cells via increasing reactive oxygen species.
Topics: Acetylcysteine; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression Regulation, Neoplastic; Glioma; Humans; Potassium Channel Blockers; Potassium Channels; Reactive Oxygen Species; Tetraethylammonium; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma.
Topics: Acetylcysteine; Brain Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hypoxia; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Pathologic; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A | 2015 |
Cytotoxic and genotoxic effects mediated by M2 muscarinic receptor activation in human glioblastoma cells.
Topics: Acetylcysteine; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Muscarinic Agonists; Receptor, Muscarinic M2; Receptors, Muscarinic | 2015 |
JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production.
Topics: Acetylcysteine; Antioxidants; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Enzyme Activation; Glioma; Humans; Hydrogen Peroxide; Intracellular Space; JNK Mitogen-Activated Protein Kinases; Mitochondria; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Reactive Oxygen Species; RNA, Small Interfering; Superoxides | 2017 |
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Mice; NADP; Radiation Tolerance; Xenograft Model Antitumor Assays | 2017 |
Antioxidant potential of Minocycline in Japanese Encephalitis Virus infection in murine neuroblastoma cells: correlation with membrane fluidity and cell death.
Topics: Acetylcysteine; Animals; Anisotropy; Anti-Bacterial Agents; Antioxidants; Blotting, Western; Brain Neoplasms; Cell Death; Cell Line, Tumor; Encephalitis, Japanese; Enzyme Inhibitors; Free Radicals; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Membrane Fluidity; Membrane Potentials; Mice; Mice, Inbred BALB C; Minocycline; Mitochondrial Membranes; Neuroblastoma; Onium Compounds; Reactive Oxygen Species | 2009 |
High-glucose and S100B stimulate glutamate uptake in C6 glioma cells.
Topics: Acetylcysteine; Brain Neoplasms; Cell Line, Tumor; Cell Lineage; Culture Media; DNA Damage; Glioma; Glucose; Guanidines; Humans; Nerve Growth Factors; S100 Calcium Binding Protein beta Subunit; S100 Proteins | 2012 |
Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction.
Topics: Acetylcysteine; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cardiolipins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Glutamate-Cysteine Ligase; Glutathione; Glutathione Transferase; Humans; Kidney; Lactones; Liver; Membrane Potential, Mitochondrial; Mice; Mitochondria; NF-kappa B; Oxidation-Reduction; Reactive Oxygen Species; Sesquiterpenes, Eudesmane; Tissue Distribution; Xenograft Model Antitumor Assays | 2012 |
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells.
Topics: Acetylcysteine; Apoptosis; Benzimidazoles; Brain Neoplasms; Buthionine Sulfoximine; Cystine; DNA Fragmentation; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Neuroblastoma; Neurons; Oxidopamine; Sympatholytics; Tumor Cells, Cultured | 2002 |
Geldanamycin induction of grp78 requires activation of reactive oxygen species via ER stress responsive elements in 9L rat brain tumour cells.
Topics: Acetylcysteine; Animals; Antibiotics, Antineoplastic; Antioxidants; Base Sequence; Benzoquinones; Brain Neoplasms; Carrier Proteins; Endoplasmic Reticulum; Heat-Shock Proteins; Kinetics; Lactams, Macrocyclic; Molecular Chaperones; Molecular Sequence Data; Oxidative Stress; Promoter Regions, Genetic; Pyrrolidines; Quinones; Rats; Reactive Oxygen Species; Response Elements; RNA, Messenger; Thiocarbamates; Transcriptional Activation; Tumor Cells, Cultured | 2003 |
MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
Topics: Acetylcysteine; Adenoviridae; Adjuvants, Immunologic; Apoptosis; Arsenic Trioxide; Arsenicals; bcl-X Protein; Brain Neoplasms; Carcinoma, Renal Cell; Caspases; Cell Division; Free Radical Scavengers; Free Radicals; Genes, Tumor Suppressor; Glioma; Glutathione Transferase; Humans; Interleukins; Kidney; Kidney Neoplasms; Oxides; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, Virus; Recombinant Fusion Proteins; Tumor Cells, Cultured | 2003 |
Melanoma differentiation-associated 7 (interleukin 24) inhibits growth and enhances radiosensitivity of glioma cells in vitro and in vivo.
Topics: Acetylcysteine; Adenoviridae; Animals; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Brain Neoplasms; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Gene Transfer Techniques; Genes, Tumor Suppressor; Glioblastoma; Glioma; Glutathione Transferase; Humans; Interleukins; Necrosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tetrazolium Salts; Thiazoles; Time Factors | 2003 |
Bone marrow chemoprotection without compromise of chemotherapy efficacy in a rat brain tumor model.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Bone Marrow; Brain Neoplasms; Chemoprevention; Disease Models, Animal; Drug Interactions; Inactivation, Metabolic; Protective Agents; Rats; Rats, Long-Evans; Sulfhydryl Compounds; Treatment Outcome | 2004 |
Prevention of hepatotoxicity but loss of antimelanoma effect with combined fotemustine and anti-oxidant treatment.
Topics: Acetylcysteine; Adult; Antineoplastic Agents; Antioxidants; Brain Neoplasms; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Lung Neoplasms; Melanoma; Nitrosourea Compounds; Organophosphorus Compounds; Treatment Outcome | 2004 |
MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
Topics: Acetylcysteine; Adenoviridae; Adjuvants, Immunologic; Apoptosis; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Brain Neoplasms; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Genes, erbB-1; Genes, Tumor Suppressor; Glioblastoma; Humans; Interleukins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2004 |
Induction of reactive oxygen intermediates-dependent programmed cell death in human malignant ex vivo glioma cells and inhibition of the vascular endothelial growth factor production by taurolidine.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspase Inhibitors; Cell Line, Tumor; Collagen Type XI; Cysteine Proteinase Inhibitors; Fas Ligand Protein; Gene Expression; Glioma; Humans; Membrane Glycoproteins; Mitochondria; Phosphatidylserines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Taurine; Thiadiazines; Vascular Endothelial Growth Factor A | 2005 |
Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cysteine Proteinase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Implants; Female; Glioma; Gliosarcoma; Infusions, Intralesional; Neoplasms, Experimental; Polymers; Rats; Rats, Inbred F344 | 2006 |
Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Radiation; Glioma; Glutathione; Hydrogen Peroxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2007 |
Signaling pathways involved in antioxidant control of glioma cell proliferation.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Glioma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2007 |
N-acetylcysteine prevents HIV gp 120-related damage of human cultured astrocytes: correlation with glutamine synthase dysfunction.
Topics: Acetylcysteine; Analysis of Variance; Astrocytes; Astrocytoma; Brain Neoplasms; Cell Death; Cell Line, Tumor; Drug Interactions; Flow Cytometry; Free Radical Scavengers; Glutamate-Ammonia Ligase; Glutamine; HIV Envelope Protein gp120; Humans; In Situ Nick-End Labeling; Male; Malondialdehyde; Middle Aged | 2007 |
Glioma regression in vitro and in vivo by a suicide combined treatment.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Adenine; Animals; Brain Neoplasms; Cell Death; Dogs; Drug Therapy, Combination; Glioma; Glucose Oxidase; Hydrogen Peroxide; Nitriles | 2008 |
Six cases of pulmonary alveolar proteinosis: presentation of unusual associations.
Topics: Acetylcysteine; Adult; Ambroxol; Biopsy; Brain Neoplasms; Bronchoalveolar Lavage Fluid; Child; Fanconi Syndrome; Female; Glioblastoma; Heart Septal Defects; Humans; Infant, Newborn; Lung; Male; Middle Aged; Oxygen Inhalation Therapy; Pulmonary Alveolar Proteinosis; Respiratory Function Tests; Tuberculosis, Pulmonary | 1995 |
Neuroprotection by glial cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX).
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Astrocytoma; Blotting, Western; Brain Neoplasms; Buthionine Sulfoximine; Cell Survival; Cerebral Cortex; Cytokines; Glutathione; Growth Substances; Humans; Hydrogen Peroxide; Mercaptoethanol; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neuroglia; Thioredoxins; Tumor Cells, Cultured | 1994 |
Effect of dietary vitamin A or N-acetylcysteine on ethylnitrosourea-induced rat gliomas.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Free Radical Scavengers; Glioma; Neuroectodermal Tumors; Pregnancy; Rats; Rats, Sprague-Dawley; Survival Analysis; Vitamin A | 1998 |
Proteasome inhibitors induce Fas-mediated apoptosis by c-Myc accumulation and subsequent induction of FasL message in human glioma cells.
Topics: Acetylcysteine; Apoptosis; Base Sequence; Brain Neoplasms; Cysteine Proteinase Inhibitors; DNA Primers; Fas Ligand Protein; fas Receptor; Glioma; Humans; Leupeptins; Membrane Glycoproteins; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured | 2001 |
Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model.
Topics: Acetylcysteine; Animals; Antimetabolites; Antineoplastic Agents, Alkylating; Aorta, Thoracic; Blood-Brain Barrier; Bone Marrow Diseases; Brain; Brain Neoplasms; Buthionine Sulfoximine; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione; Infusions, Intra-Arterial; Lung Neoplasms; Rats; Rats, Long-Evans; Tissue Distribution; Xenograft Model Antitumor Assays | 2001 |
[A new substance, N-acetyl-L-cysteine, in the treatment of tracheotomized patients].
Topics: Acetylcysteine; Adult; Aged; Brain Neoplasms; Cerebrovascular Disorders; Child; Craniocerebral Trauma; Female; Humans; Male; Middle Aged; Tracheotomy | 1965 |