acetylcysteine and Bone Loss, Osteoclastic

acetylcysteine has been researched along with Bone Loss, Osteoclastic in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's3 (21.43)29.6817
2010's6 (42.86)24.3611
2020's4 (28.57)2.80

Authors

AuthorsStudies
Fu, L; Hao, Y; Wang, N1
Cao, N; Deng, Y; Fu, R; Hou, Y; Liu, X; Xiang, X; Xin, X; Yang, B; Yang, M; Yu, W; Zhou, Y1
Fang, Y; Gong, W; Liu, M; Liu, S; Liu, Y; Qin, L; Yu, Y; Zhang, Q; Zhao, L; Zhu, L1
Chen, J; Li, X; Xiao, Q; Zeng, J1
Guo, H; Mei, L; Pan, JX; Shun, C; Tang, F; Wang, B; Xia, WF; Xiong, F; Xiong, L; Xiong, WC; Zeng, P; Zhao, K1
Jung, JU; Mei, L; Shi, XM; Shun, C; Xia, WF; Xiong, L; Xiong, S; Xiong, WC1
Cao, JJ; Picklo, MJ1
Hong, S; Huh, JE; Jeong, W; Lee, SY; Rhee, SG; Shim, JK1
Badger, TM; Blackburn, ML; Chen, JR; Lazarenko, OP; Lumpkin, CK; Ronis, MJ; Shankar, K1
Jia, P; Li, B; Li, K; Xu, YJ; Yang, H; Zhang, W; Zhang, ZL1
Kotowicz, MA; Nicholson, GC; Sanders, KM1
Badger, TM; Chen, JR; Nagarajan, S; Ronis, MJ; Shankar, K1
Badger, TM; Chen, JR; Haley, R; Hidestrand, M; Liu, X; Lumpkin, CK; Perrien, DS; Ronis, MJ; Shankar, K; Skinner, RA1
Chambers, TJ; Fuller, K; Hall, TJ; Jeker, H; Schaeublin, M1

Trials

1 trial(s) available for acetylcysteine and Bone Loss, Osteoclastic

ArticleYear
Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study.
    Translational research : the journal of laboratory and clinical medicine, 2007, Volume: 150, Issue:4

    Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Biomarkers; Bone Resorption; Calcium; Cholecalciferol; Collagen Type I; Double-Blind Method; Female; Humans; Mice; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Pilot Projects; Postmenopause

2007

Other Studies

13 other study(ies) available for acetylcysteine and Bone Loss, Osteoclastic

ArticleYear
Trimethylamine-N-Oxide Promotes Osteoclast Differentiation and Bone Loss via Activating ROS-Dependent NF-κB Signaling Pathway.
    Nutrients, 2022, Sep-23, Volume: 14, Issue:19

    Topics: Acetylcysteine; Actins; Animals; Bone Resorption; Cattle; Cell Differentiation; Methylamines; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Nitriles; Osteoclasts; Osteogenesis; Osteoporosis; Oxides; Proto-Oncogene Proteins c-fos; RANK Ligand; Reactive Oxygen Species; Signal Transduction; Sulfones; TNF Receptor-Associated Factor 6

2022
N-Acetyl-l-cysteine-Derived Carbonized Polymer Dots with ROS Scavenging via Keap1-Nrf2 Pathway Regulate Alveolar Bone Homeostasis in Periodontitis.
    Advanced healthcare materials, 2023, Volume: 12, Issue:26

    Topics: Acetylcysteine; Animals; Antioxidants; Bone Resorption; Homeostasis; Humans; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Osteogenesis; Oxidative Stress; Periodontitis; Reactive Oxygen Species

2023
Curculigoside attenuates oxidative stress and osteoclastogenesis via modulating Nrf2/NF-κB signaling pathway in RAW264.7 cells.
    Journal of ethnopharmacology, 2021, Jul-15, Volume: 275

    Topics: Acetylcysteine; Actins; Animals; Benzoates; Bone Resorption; Cell Differentiation; Cell Survival; Drug Synergism; Glucosides; Hydrogen Peroxide; Kelch-Like ECH-Associated Protein 1; Mice; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NF-E2-Related Factor 2; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Oxidative Stress; RANK Ligand; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; Tartrate-Resistant Acid Phosphatase

2021
Advanced oxidation protein products aggravate age‑related bone loss by increasing sclerostin expression in osteocytes via ROS‑dependent downregulation of Sirt1.
    International journal of molecular medicine, 2021, Volume: 47, Issue:6

    Topics: Acetophenones; Acetylcysteine; Adaptor Proteins, Signal Transducing; Advanced Oxidation Protein Products; Animals; Bone Resorption; Cell Line; Down-Regulation; Male; Mice, Inbred C57BL; Osteocytes; Osteogenesis; Osteoporosis; Reactive Oxygen Species; Sirtuin 1

2021
APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress.
    Cell death & disease, 2018, 10-22, Volume: 9, Issue:11

    Topics: Acetylcysteine; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Apoptosis; Bone and Bones; Bone Resorption; Brain; Cells, Cultured; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Osteoblasts; Osteogenesis; Oxidative Stress; Reactive Oxygen Species

2018
Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013, Volume: 28, Issue:10

    Topics: Acetylcysteine; Acid Phosphatase; Adipogenesis; Aging; Amyloid beta-Peptides; Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Cell Differentiation; Cell Lineage; Cells, Cultured; Cricetinae; Humans; Isoenzymes; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Organ Size; Osteoblasts; Osteogenesis; Osteoporosis; Tartrate-Resistant Acid Phosphatase

2013
N-acetylcysteine supplementation decreases osteoclast differentiation and increases bone mass in mice fed a high-fat diet.
    The Journal of nutrition, 2014, Volume: 144, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Body Weight; Bone Density; Bone Resorption; Cell Differentiation; Cell Line, Tumor; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Glutathione; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Osteoclasts

2014
TRP14 inhibits osteoclast differentiation via its catalytic activity.
    Molecular and cellular biology, 2014, Sep-15, Volume: 34, Issue:18

    Topics: Acetylcysteine; Actins; Animals; Bone Resorption; Catalytic Domain; Cell Differentiation; Cell Line; Gene Expression Regulation; Humans; MAP Kinase Signaling System; Mice; Mutation; NF-kappa B; NIH 3T3 Cells; Onium Compounds; Osteoclasts; RANK Ligand; Reactive Oxygen Species; Thioredoxins

2014
Inhibition of NADPH oxidases prevents chronic ethanol-induced bone loss in female rats.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:3

    Topics: Acetylcysteine; Animals; Bone Resorption; Cell Line; Enzyme Inhibitors; Estradiol; Ethanol; Female; NADPH Oxidases; Onium Compounds; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2011
Ferric ion could facilitate osteoclast differentiation and bone resorption through the production of reactive oxygen species.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2012, Volume: 30, Issue:11

    Topics: Acetylcysteine; Animals; Bone Resorption; Cell Differentiation; Cell Line; Ferric Compounds; Glutathione; Iron; Male; Mice; Mice, Inbred ICR; Osteoclasts; Oxidative Stress; Quaternary Ammonium Compounds; RANK Ligand; Reactive Oxygen Species

2012
Protective effects of estradiol on ethanol-induced bone loss involve inhibition of reactive oxygen species generation in osteoblasts and downstream activation of the extracellular signal-regulated kinase/signal transducer and activator of transcription 3/
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Bone Resorption; Cell Differentiation; Cell Line; Cells, Cultured; Estradiol; Ethanol; Female; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Osteoblasts; Oxidative Stress; RANK Ligand; Rats; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Skull; STAT3 Transcription Factor

2008
Chronic ethanol consumption inhibits postlactational anabolic bone rebuilding in female rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2008, Volume: 23, Issue:3

    Topics: Acetylcysteine; Adipocytes; Alcoholism; Animals; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Central Nervous System Depressants; Ethanol; Female; Free Radical Scavengers; Lactation; Osteogenesis; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Risk Factors; Signal Transduction; Tibia; Time Factors; Tumor Necrosis Factor-alpha

2008
The role of reactive oxygen intermediates in osteoclastic bone resorption.
    Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1

    Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Bone Resorption; Cell Survival; Cells, Cultured; Deferoxamine; Free Radical Scavengers; NF-kappa B; Osteoclasts; Pyrrolidines; Rats; Reactive Oxygen Species; Thiocarbamates

1995