acetylcysteine and Blood Pressure, High

acetylcysteine has been researched along with Blood Pressure, High in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.77)	18.7374
1990's	5 (9.43)	18.2507
2000's	31 (58.49)	29.6817
2010's	14 (26.42)	24.3611
2020's	1 (1.89)	2.80

Authors

Authors	Studies
Chukhliaev, PV; Garbuzov, AA; Khavkina, DA; Ploskireva, AA; Ruzhentsova, TA	1
Adamcova, M; Aziriova, S; Balazova, L; Celec, P; Krajcirovicova, K; Pechanova, O; Repova, K; Simko, F; Tothova, L; Vrankova, S; Zorad, S	1
Fan, NC; Hsu, CN; Huang, LT; Tain, YL; Tsai, CM	1
Carbajosa, NA; Congo Carbajosa, NA; Corradi, G; Gironacci, MM; Guil, MJ; Vatta, MS; Verrilli, MA	1
Dasgupta, C; Huang, X; Li, Y; Wang, L; Xiao, D; Zhang, L	1
Bonaterra, G; Dugi, KA; Edler, L; Hildebrandt, W; Kinscherf, R; Sauer, R	1
Chen, CC; Huang, LT; Lin, YJ; Sheen, JM; Tai, IH; Tain, YL; Tiao, MM; Yu, HR	1
Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC	1
Chan, JY; Hsu, CN; Lee, CT; Tain, YL	1
Couture, R; de Champlain, J; El Midaoui, A; Fantus, IG; Ismael, MA; Lu, H	1
Dominiczak, AF; Fields, L; Graham, D; Hamilton, CA; Koh-Tan, HH; McBride, MW; Nicoll, G; Young, B	1
Gadag, V; Gill, VD; Han, Y; Randell, E; Vasdev, S	1
Albini, A; Cammarota, R; De Flora, S; Donatelli, F; Noonan, DM; Pennesi, G	1
Dobesova, Z; Kunes, J; Pechanova, O; Vrankova, S; Zicha, J	1
Barta, A; Janega, P; Parohova, J; Pechanova, O; Simko, F; Vrankova, S	1
He, RX; Hu, CP; Luo, YQ; Su, XL; Xiang, YH	1
Anand-Srivastava, MB; Li, Y; Sandoval, YH	1
Ieiri, I; Iwase, M; Kitazono, T; Matsuyama, N; Ohdo, S; Sonoki, K; Takata, Y	1
de Oliveira, MG; Krieger, MH; Ricardo, KF; Shishido, SM	1
Barrios, V; Calderón, A; Lahera, V; Navarro-Cid, J; Ruilope, LM	1
Chulak, C; de Champlain, J; Girouard, H; Lamontagne, D; LeJossec, M	1
Chulak, C; de Champlain, J; Girouard, H; Lejossec, M; Wu, L	1
Adamy, C; Adubeiro, S; Badoual, T; Bourin, MC; Bourraindeloup, M; Cailleret, M; Candiani, G; Dubois-Rande, JL; Hittinger, L; Pecker, F; Roudot-Thoraval, F; Su, JB	1
Chulak, C; de Champlain, J; Denault, C; Girouard, H	1
Fujii, S; Igarashi, J; Kosaka, H; Zhang, L	1
Hutchings, S; Pang, CC; Song, D	1
Delles, C; John, S; Oehmer, S; Schmidt, BM; Schmieder, RE; Schneider, MP; Schwarz, TK	1
Dobesová, Z; Kunes, J; Pechánová, O; Rauchová, H; Vokurková, M; Zicha, J	1
Barbosa, E; Chang, EY; Paintlia, MK; Singh, A; Singh, I	1
Dobesová, Z; Jendeková, L; Kojsová, S; Kunes, J; Pechánová, O; Zicha, J	1
Anand-Srivastava, MB; Daou, GB; Lappas, G	1
Barrett, BJ; Parfrey, PS	1
de Macedo Possamai, V; Guo, Z; Hu, L; McKenzie, KU; Miao, Y; Mondo, CK; Schyvens, CG; Whitworth, JA; Zhang, Y	1
Dwyer, TM; Hughson, MD; Jordan, S; Manning, RD; Rose, RA; Tian, N	1
Thaha, M; Tomino, Y; Yogiantoro, M	1
Dobesová, Z; Dovinová, I; Jendeková, L; Kojsová, S; Kunes, J; Paulis, L; Pechánová, O; Simko, F; Sládková, M; Zenebe, W; Zicha, J	1
Biswas, SK; de Faria, JB	1
Dobesová, Z; Kunes, J; Zicha, J	1
Chhabra, P; Doctor, A; Forbes, MS; Gaston, B; Karlinsey, MZ; Laubach, VE; Macdonald, T; Palmer, LA; Sheram, ML	1
Macarthur, H; Westfall, TC; Wilken, GH	1
de Souza, HP; dos Santos, L; Garcia, JA; Krieger, MH; Moura, AL; Ricardo, KF; Shishido, SM; Spadari-Bratfisch, RC; Wanschel, AC	1
Berchio, A; Bergamini, S; Brocato, L; Della Casa, L; Gigliardi, VR; Iannone, A; Manzato, E; Martina, V; Masha, A; Massarenti, P; Settanni, F	1
Croft, KD; Krug, S; Langton, LK; Mori, TA; Vickers, JJ; Whitworth, JA; Zhang, Y	1
del Arco, C; Lahera, V; Ruilope, LM; Suárez, C	1
Carbonell, LF; Inglés, AC; Quesada, T; Ruiz, FJ; Salom, MG; Vicente, E	1
Longerich, L; Mian, T; Parai, S; Prabhakaran, V; Vasdev, S	1
Ford, CA; Gadag, V; Longerich, L; Vasdev, S; Wadhawan, S	1
Besner, JG; Bouchard, JF; Cabassi, A; de Champlain, J; Dumont, EC; Girouard, H; Lamontagne, D; Le Jossec, M	2
Chun, TH; Doi, K; Fukunaga, Y; Inoue, M; Itoh, H; Masatsugu, K; Mori, Y; Nakao, K; Ogawa, Y; Saito, T; Sawada, N; Tanaka, T; Yamahara, K; Yamashita, J	1
Ford, CA; Gadag, V; Longerich, L; Parai, S; Vasdev, S; Wadhawan, S	1
Bodemann, T; Hochrein, H; Langescheid, C	1
Blumstein, CG	1

Reviews

3 review(s) available for acetylcysteine and Blood Pressure, High

Article	Year
Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. Journal of the National Cancer Institute, 2010, Jan-06, Volume: 102, Issue:1 Topics: Acetylcysteine; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplastic Agents; Atrial Fibrillation; Blood Coagulation; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Flavonoids; Free Radical Scavengers; Heart; Humans; Hypertension; Patient Care Team; Phenols; Platelet Aggregation Inhibitors; Polyphenols; Stroke Volume; Venous Thromboembolism; Ventricular Dysfunction, Left	2010
Clinical practice. Preventing nephropathy induced by contrast medium. The New England journal of medicine, 2006, Jan-26, Volume: 354, Issue:4 Topics: Acetylcysteine; Aged; Contrast Media; Coronary Angiography; Diabetes Mellitus, Type 2; Fluid Therapy; Humans; Hypertension; Kidney Diseases; Male; Practice Guidelines as Topic; Risk Factors	2006
Drug treatment in bronchial asthma. Seminars in drug treatment, 1973,Spring, Volume: 2, Issue:4 Topics: Acetylcysteine; Anti-Bacterial Agents; Asthma; Bronchodilator Agents; Caffeine; Drug Combinations; Ephedrine; Epinephrine; Expectorants; Glucocorticoids; Guaifenesin; Humans; Hypertension; Isoproterenol; Mucus; Sympathomimetics; Theophylline; Xanthines	1973

Trials

6 trial(s) available for acetylcysteine and Blood Pressure, High

Article	Year
Oral N-acetylcysteine reduces plasma homocysteine concentrations regardless of lipid or smoking status. The American journal of clinical nutrition, 2015, Volume: 102, Issue:5 Topics: Acetylcysteine; Administration, Oral; Adult; Antihypertensive Agents; Antioxidants; Biotransformation; Cholesterol; Cysteine; Double-Blind Method; Glutathione; Homocysteine; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Leukocytes, Mononuclear; Male; Middle Aged; Smoking; Triglycerides	2015
Telmisartan and N-acetylcysteine suppress group V secretory phospholipase A2 expression in TNFα-stimulated human endothelial cells and reduce associated atherogenicity. Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:4 Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Atherosclerosis; Benzimidazoles; Benzoates; Chemokine CCL2; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Group V Phospholipases A2; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Middle Aged; RNA, Messenger; Telmisartan; Tumor Necrosis Factor-alpha	2012
N-acetylcysteine potentiates the antihypertensive effect of ACE inhibitors in hypertensive patients. Blood pressure, 2002, Volume: 11, Issue:4 Topics: Acetylcysteine; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Smoking	2002
Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension. American journal of hypertension, 2005, Volume: 18, Issue:8 Topics: Acetylcholine; Acetylcysteine; Adult; Ascorbic Acid; Blood Flow Velocity; Endothelium, Vascular; Female; Forearm; Free Radical Scavengers; Humans; Hypertension; Infusions, Intra-Arterial; Male; Middle Aged; Nitroprusside; Superoxides; Vasodilation; Vasodilator Agents	2005
Intravenous N-acetylcysteine during haemodialysis reduces the plasma concentration of homocysteine in patients with end-stage renal disease. Clinical drug investigation, 2006, Volume: 26, Issue:4 Topics: Acetylcysteine; Adult; Aged; Blood Pressure; Blood Proteins; Diabetic Nephropathies; Drug Administration Schedule; Female; Heart Rate; Hematocrit; Homocysteine; Humans; Hypertension; Infusions, Intravenous; Kidney Calculi; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Treatment Outcome; Urticaria	2006
Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes. Diabetes care, 2008, Volume: 31, Issue:5 Topics: Acetylcysteine; Administration, Oral; Aged; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Endothelium, Vascular; Humans; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Placebos; Systole	2008

Other Studies

44 other study(ies) available for acetylcysteine and Blood Pressure, High

Article	Year
[Effect of anticoagulant therapy on the course of COVID-19 in comorbid patients]. Voprosy virusologii, 2021, 03-07, Volume: 66, Issue:1 Topics: Acetylcysteine; Aged; Aged, 80 and over; Anticoagulants; Antiviral Agents; Atrial Fibrillation; Azithromycin; Cohort Studies; Comorbidity; Coronary Disease; COVID-19; COVID-19 Drug Treatment; Dabigatran; Disseminated Intravascular Coagulation; Female; Humans; Hypertension; Indoles; Interferon alpha-2; Intracranial Arteriosclerosis; Male; Middle Aged; Pyrazoles; Pyridones; Rivaroxaban; SARS-CoV-2; Severity of Illness Index; Survival Analysis	2021
Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril. International journal of molecular sciences, 2017, Jul-25, Volume: 18, Issue:8 Topics: Acetylcysteine; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension; Light; Male; Melatonin; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Ventricular Remodeling	2017
N-acetylcysteine prevents hypertension via regulation of the ADMA-DDAH pathway in young spontaneously hypertensive rats. BioMed research international, 2013, Volume: 2013 Topics: Acetylcysteine; Amidohydrolases; Animals; Arginine; Blood Pressure; Glutathione; Humans; Hypertension; Metabolic Networks and Pathways; Nitric Oxide; Oxidative Stress; Rats; Superoxides	2013
Tyrosine hydroxylase is short-term regulated by the ubiquitin-proteasome system in PC12 cells and hypothalamic and brainstem neurons from spontaneously hypertensive rats: possible implications in hypertension. PloS one, 2015, Volume: 10, Issue:2 Topics: Acetylcysteine; Animals; Brain Stem; Hypertension; Hypothalamus; Male; Neurons; PC12 Cells; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Rats; Rats, Inbred SHR; Rats, Wistar; Tyrosine 3-Monooxygenase; Ubiquitin	2015
Antenatal Antioxidant Prevents Nicotine-Mediated Hypertensive Response in Rat Adult Offspring. Biology of reproduction, 2015, Volume: 93, Issue:3 Topics: Acetylcysteine; Angiotensin II; Animals; Antioxidants; Body Weight; Enzyme Activation; Female; Humans; Hypertension; Muscle Relaxation; Muscle, Smooth, Vascular; Nicotine; Nicotinic Agonists; Phorbol 12,13-Dibutyrate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species	2015
Maternal N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and prevents programmed hypertension in male offspring exposed to prenatal dexamethasone and postnatal high-fat diet. Nitric oxide : biology and chemistry, 2016, Feb-29, Volume: 53 Topics: Acetylcysteine; Animals; Dexamethasone; Diet, High-Fat; Female; Hydrogen Sulfide; Hypertension; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley	2016
N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. Biology of reproduction, 2016, Volume: 95, Issue:1 Topics: Acetylcysteine; Animals; Arginine; Blood Pressure; Female; Fetal Development; Hydrogen Sulfide; Hypertension; Kidney; Male; Nitric Oxide; Pre-Eclampsia; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Suramin	2016
Maternal melatonin or N-acetylcysteine therapy regulates hydrogen sulfide-generating pathway and renal transcriptome to prevent prenatal N American journal of obstetrics and gynecology, 2016, Volume: 215, Issue:5 Topics: Acetylcysteine; Administration, Oral; Animals; Antioxidants; Biomarkers; Female; Fetal Development; Hydrogen Sulfide; Hypertension; Kidney; Male; Melatonin; NG-Nitroarginine Methyl Ester; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcriptome	2016
Comparative effects of N-acetyl-L-cysteine and ramipril on arterial hypertension, insulin resistance, and oxidative stress in chronically glucose-fed rats. Canadian journal of physiology and pharmacology, 2008, Volume: 86, Issue:11 Topics: Acetylcysteine; Aldehydes; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Diet; Free Radical Scavengers; Glucose; Hypertension; Insulin Receptor Substrate Proteins; Insulin Resistance; Lipid Peroxidation; Liver; Male; Malondialdehyde; Muscle, Skeletal; NADPH Oxidases; Oxidative Stress; Oxygen Consumption; Ramipril; Rats; Rats, Wistar	2008
Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of hypertension, 2009, Volume: 27, Issue:8 Topics: Acetylcysteine; Animals; Glutathione Transferase; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Kidney; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxides; Systole; Tetrazoles	2009
Fructose and moderately high dietary salt-induced hypertension: prevention by a combination of N-acetylcysteine and L-arginine. Molecular and cellular biochemistry, 2010, Volume: 337, Issue:1-2 Topics: Acetylcysteine; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Fructose; Heart; Hypertension; Kidney; Liver; Myocardium; Organ Size; Rats; Rats, Inbred WKY; Sodium Chloride, Dietary	2010
Contribution of neuronal nitric oxide (no) synthase to N-acetylcysteine-induced increase of NO synthase activity in the brain of normotensive and hypertensive rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2009, Volume: 60, Issue:4 Topics: Acetylcysteine; Animals; Blood Pressure; Body Weight; Brain; Brain Stem; Cerebellum; Dose-Response Relationship, Drug; Free Radical Scavengers; Heart; Hypertension; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Size; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity	2009
Effect of nuclear factor kappa B inhibition on L-NAME-induced hypertension and cardiovascular remodelling. Journal of hypertension, 2010, Volume: 28 Suppl 1 Topics: Acetylcysteine; Animals; Blood Pressure; Hypertension; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Ventricular Remodeling	2010
[A study of the related pathways of oxidative stress in chronic intermittent hypoxia rats and the effect of N-acetylcysteine]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2010, Volume: 33, Issue:12 Topics: Acetylcysteine; Animals; Antioxidants; Blood Pressure; Hypertension; Hypoxia; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sleep Apnea, Obstructive	2010
Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR. Cellular signalling, 2011, Volume: 23, Issue:11 Topics: Acetylcysteine; Adenylyl Cyclases; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Colforsin; CSK Tyrosine-Protein Kinase; ErbB Receptors; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; src-Family Kinases; Transcriptional Activation	2011
Characterization of the hypotensive effect of S-nitroso-N-acetylcysteine in normotensive and hypertensive conscious rats. Nitric oxide : biology and chemistry, 2002, Volume: 7, Issue:1 Topics: Acetylcysteine; Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Drug Stability; Drug Synergism; Drug Therapy, Combination; Hypertension; Male; Rats; Rats, Wistar; Sulfhydryl Compounds; Vasodilation	2002
Chronic antioxidant treatment improves sympathetic functions and beta-adrenergic pathway in the spontaneously hypertensive rats. Journal of hypertension, 2003, Volume: 21, Issue:1 Topics: Acetylcysteine; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Antioxidants; Aorta; Binding Sites; Binding, Competitive; Blood Pressure; Catecholamines; Drug Administration Schedule; Heart Rate; Hypertension; In Vitro Techniques; Isoproterenol; Male; Melatonin; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Sympathetic Nervous System	2003
N-acetylcysteine improves nitric oxide and alpha-adrenergic pathways in mesenteric beds of spontaneously hypertensive rats. American journal of hypertension, 2003, Volume: 16, Issue:7 Topics: Acetylcysteine; Adrenergic Fibers; Animals; Hemodynamics; Hypertension; Mesenteric Arteries; Nitric Oxide; Rats; Splanchnic Circulation	2003
N-acetylcysteine treatment normalizes serum tumor necrosis factor-alpha level and hinders the progression of cardiac injury in hypertensive rats. Circulation, 2004, Oct-05, Volume: 110, Issue:14 Topics: Acetylcysteine; Animals; Antioxidants; Collagen; Disease Progression; Drug Evaluation, Preclinical; Glutathione; Heart Ventricles; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Sodium Chloride, Dietary; Sphingomyelin Phosphodiesterase; Tumor Necrosis Factor-alpha; Ultrasonography; Ventricular Dysfunction, Left; Ventricular Remodeling	2004
Treatment by n-acetylcysteine and melatonin increases cardiac baroreflex and improves antioxidant reserve. American journal of hypertension, 2004, Volume: 17, Issue:10 Topics: Acetylcysteine; Animals; Antioxidants; Baroreflex; Blood Pressure; Catecholamines; Erythrocytes; Glutathione Peroxidase; Heart; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Male; Melatonin; Organ Size; Oxidoreductases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase	2004
Effects of thiol antioxidant on reduced nicotinamide adenine dinucleotide phosphate oxidase in hypertensive Dahl salt-sensitive rats. Free radical biology & medicine, 2004, Dec-01, Volume: 37, Issue:11 Topics: Acetylcholine; Acetylcysteine; Animals; Antioxidants; Blood Pressure; Dinoprost; Endothelium, Vascular; Hydrogen Peroxide; Hypertension; Kidney Glomerulus; Male; NADPH Oxidases; Oxidative Stress; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride; Superoxides; Thromboxane B2; Up-Regulation	2004
Chronic N-acetylcysteine prevents fructose-induced insulin resistance and hypertension in rats. European journal of pharmacology, 2005, Jan-31, Volume: 508, Issue:1-3 Topics: Acetylcysteine; Adrenergic alpha-Agonists; Animals; Blood Pressure; Dinoprost; Dose-Response Relationship, Drug; Fructose; Glucose Tolerance Test; Hypertension; Insulin Resistance; Male; Methoxamine; Random Allocation; Rats; Rats, Sprague-Dawley; Triglycerides	2005
Chronic N-acetylcysteine administration prevents development of hypertension in N(omega)-nitro-L-arginine methyl ester-treated rats: the role of reactive oxygen species. Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:5 Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Cyclic N-Oxides; Drug Interactions; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Reactive Oxygen Species; Spin Labels	2005
The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats. American journal of obstetrics and gynecology, 2005, Volume: 193, Issue:3 Pt 2 Topics: Acetylcysteine; Animals; Blood Pressure; Disease Models, Animal; Female; Fetal Weight; Hypertension; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Uterus	2005
Effect of chronic N-acetylcysteine treatment on the development of spontaneous hypertension. Clinical science (London, England : 1979), 2006, Volume: 110, Issue:2 Topics: Acetylcysteine; Aging; Animals; Antioxidants; Glutathione; Heart Ventricles; Hypertension; Kidney; Male; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species	2006
Oxidative stress contributes to the enhanced expression of Gialpha proteins and adenylyl cyclase signaling in vascular smooth muscle cells from spontaneously hypertensive rats. Journal of hypertension, 2005, Volume: 23, Issue:12 Topics: Acetylcysteine; Adenylyl Cyclases; Animals; Antioxidants; Cells, Cultured; Colforsin; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Hypertension; Isoproterenol; MAP Kinase Signaling System; Models, Biological; Muscle, Smooth, Vascular; Onium Compounds; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Superoxides	2005
N-acetylcysteine antagonizes the development but does not reverse ACTH-induced hypertension in the rat. Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:2 Topics: Acetylcysteine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Disease Models, Animal; Free Radical Scavengers; Hypertension; Male; Rats; Rats, Sprague-Dawley; Treatment Outcome	2006
N-Acetylcysteine improves renal dysfunction, ameliorates kidney damage and decreases blood pressure in salt-sensitive hypertension. Journal of hypertension, 2006, Volume: 24, Issue:11 Topics: Acetylcysteine; Animals; Blood Pressure; Disease Models, Animal; Free Radical Scavengers; Glomerular Filtration Rate; Glutathione; Hypertension; Kidney Diseases; Male; Oxidative Stress; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary	2006
The effect of N-acetylcysteine and melatonin in adult spontaneously hypertensive rats with established hypertension. European journal of pharmacology, 2007, Apr-30, Volume: 561, Issue:1-3 Topics: Acetylcysteine; Alkadienes; Animals; Antioxidants; Blood Pressure; Blotting, Western; Free Radical Scavengers; Hypertension; Male; Melatonin; Myography; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Vasoconstriction	2007
Which comes first: renal inflammation or oxidative stress in spontaneously hypertensive rats? Free radical research, 2007, Volume: 41, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Age Factors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; Disease Models, Animal; Disease Progression; DNA Damage; Glutathione; Hypertension; Kidney Cortex; Male; NADPH Oxidases; Nephritis; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Tyrosine	2007
Antihypertensive mechanisms of chronic captopril or N-acetylcysteine treatment in L-NAME hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:12 Topics: Acetylcysteine; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Pentolinium Tartrate; Rats; Rats, Wistar; Tetraethylammonium	2006
S-nitrosothiols signal hypoxia-mimetic vascular pathology. The Journal of clinical investigation, 2007, Volume: 117, Issue:9 Topics: Acetylcysteine; Animals; Erythrocytes; Glutathione; Hypertension; Hypoxia; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Nitro Compounds; Nitroso Compounds; Oxygen; Pulmonary Artery; S-Nitrosothiols; Signal Transduction	2007
Oxidative stress attenuates NO-induced modulation of sympathetic neurotransmission in the mesenteric arterial bed of spontaneously hypertensive rats. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1 Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Blood Pressure; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Splanchnic Circulation; Superoxides; Sympathetic Nervous System	2008
S-nitroso-N-acetylcysteine (SNAC) prevents myocardial alterations in hypercholesterolemic LDL receptor knockout mice by antiinflammatory action. Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:1 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Blood Pressure; CD40 Ligand; Gene Expression Regulation, Enzymologic; Hypercholesterolemia; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Nitric Oxide Synthase Type III; Receptors, LDL	2008
N-Acetylcysteine prevents but does not reverse dexamethasone-induced hypertension. Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:8 Topics: Acetylcysteine; Animals; Blood Pressure; Dexamethasone; Energy Metabolism; F2-Isoprostanes; Hypertension; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley	2008
N-acetylcysteine potentiates the antihypertensive effect of angiotensin converting enzyme inhibitors. American journal of hypertension, 1995, Volume: 8, Issue:8 Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, Combination; Humans; Hypertension	1995
N-acetyl-L-cysteine potentiates depressor response to captopril and enalaprilat in SHRs. The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2 Topics: Acetylcysteine; Animals; Blood Pressure; Captopril; Drug Synergism; Enalaprilat; Hypertension; Male; Rats; Rats, Inbred SHR	1994
N-acetyl cysteine attenuates ethanol induced hypertension in rats. Artery, 1995, Volume: 21, Issue:6 Topics: Acetaldehyde; Acetylcysteine; Administration, Oral; Animals; Aorta; Blood Platelets; Blood Pressure; Body Weight; Calcium; Cytosol; Energy Intake; Ethanol; Heart; Hypertension; Kidney; Lipid Peroxidation; Liver; Male; Muscle, Smooth, Vascular; Myocardium; Organ Size; Rats; Rats, Inbred WKY; Renal Circulation; Thiobarbituric Acid Reactive Substances	1995
Role of aldehydes in fructose induced hypertension. Molecular and cellular biochemistry, 1998, Volume: 181, Issue:1-2 Topics: Acetylcysteine; Aldehydes; Animals; Blood Platelets; Blood Pressure; Body Weight; Calcium; Diet; Drinking; Eating; Fructose; Hypertension; Kidney; Lipofuscin; Organ Size; Rats; Rats, Inbred WKY	1998
Effect of antioxidant treatments on nitrate tolerance development in normotensive and hypertensive rats. Journal of hypertension, 2000, Volume: 18, Issue:2 Topics: Acetylcysteine; Animals; Antioxidants; Coronary Vessels; Drug Tolerance; Endothelium, Vascular; Hypertension; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitrates; Nitroprusside; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serotonin; Vasodilation	2000
Oxidative stress augments secretion of endothelium-derived relaxing peptides, C-type natriuretic peptide and adrenomedullin. Journal of hypertension, 2000, Volume: 18, Issue:5 Topics: Acetylcysteine; Adrenomedullin; Animals; Antioxidants; Arteriosclerosis; Base Sequence; Cattle; Cells, Cultured; DNA Primers; Endothelium, Vascular; Gene Expression; Humans; Hydrogen Peroxide; Hypertension; Natriuretic Peptide, C-Type; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peptides; RNA, Messenger; Vasodilation	2000
Aldehyde induced hypertension in rats: prevention by N-acetyl cysteine. Artery, 1998, Volume: 23, Issue:1 Topics: Acetylcysteine; Aldehydes; Animals; Arterioles; Blood Platelets; Blood Pressure; Body Weight; Calcium; Carbohydrate Metabolism; Diet; Drinking; Eating; Energy Intake; Hyperplasia; Hypertension; Insulin Resistance; Kidney; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitrites; Organ Size; Pyruvaldehyde; Rats; Rats, Inbred WKY; Renal Artery; Viscera	1998
Effects of chronic N-acetylcysteine treatment on the actions of peroxynitrite on aortic vascular reactivity in hypertensive rats. Journal of hypertension, 2001, Volume: 19, Issue:7 Topics: Acetylcholine; Acetylcysteine; Animals; Aorta; Drug Synergism; Free Radical Scavengers; Glutathione; Glutathione Disulfide; Hypertension; In Vitro Techniques; Isoproterenol; Male; Malondialdehyde; Nitrates; Nitroprusside; Peroxynitrous Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents; Vasomotor System	2001
[Nitrate tolerance and its management by N-acetylcysteine (studies of patients with severe chronic heart failure)]. Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:5 Topics: Acetylcysteine; Cardiomyopathy, Dilated; Coronary Disease; Drug Therapy, Combination; Drug Tolerance; Female; Heart Failure; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nitroglycerin	1989