Compounds > acetylcysteine

acetylcysteine and Blood Poisoning

acetylcysteine has been researched along with Blood Poisoning in 56 studies

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.79)18.7374
1990's6 (10.71)18.2507
2000's17 (30.36)29.6817
2010's25 (44.64)24.3611
2020's7 (12.50)2.80

Authors

AuthorsStudies
Chen, W; Geng, Y; Liang, H; Liu, J; Liu, S; Ouyang, J; Peng, N; Su, L; Tang, Y; Wan, Y; Wang, JH; Yu, B; Yuan, F1
Bagio, E; Barichello, T; Bonfante, SRSA; de Carli, RJ; de Oliveira Junior, AN; de Oliveira, MP; Della Giustina, A; Dos Santos, TM; Engel, NA; Goldim, MPS; Joaquim, L; Kanis, LA; Metzker, KLL; Muttini, S; Novochadlo, M; Petronilho, F; Rezin, GT; Tenfen, L1
Constantino, L; Dal-Pizzol, F; Damásio, D; Fraga, C; Gonçalves, RC; Michels, M; Ritter, C1
Fan, H; Le, JW; Zhu, JH1
Basile, K; Colaco, CMG; Draper, J; Ferguson, PE1
Dou, Q; Gan, H; Tong, H; Yang, Y; Zhang, H1
Bedreag, OH; Bratu, LM; Bratu, T; Cradigati, CA; Dinu, A; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sandesc, M; Sarandan, M; Stan, AT1
Levi, M; Scully, M; Singer, M1
Ganaes, JOF; Lopes-Pires, ME; Naime, ACA1
Boroumand, N; Hashemy, SI; Peivandi Yazdi, A; Razavi, M; Salehi, M; Sheikh, S1
Cate, SA; Chen, J; Dominguez, M; Fu, X; Konkle, BA; López, JA; Osborn, W; Özpolat, T1
Amathieu, R; Chemit, M; Compagnon, P; Costentin, C; Dhonneur, G; Levesque, E; Merle, JC1
Visvanathan, V1
Dal-Pizzol, F; de Castro, AA; Quevedo, J; Steckert, AV1
Fu, J; Ji, K; Li, G; Luan, T; Zang, B; Zhao, Y1
Abdollahi, M; Ahmadi, A; Ahmadi, KH; Chelkeba, L; Mojtahedzadeh, M; Mousavi, M; Najafi, A; Najmeddin, F1
Barbosa de Castro, CM; Dornelas de Andrade, AF; Filho, CA; Galvão, AM; Melo-Junior, MR; Silva, LA; Silva, RA; Souza Maia, MB; Streck, EL; Wanderley, MS1
Chao, J; Chao, L; Chen, CW; Huang, YW; Lin, CF; Lin, WC; Lin, YS1
Bedreag, OH; Cradigati, CA; Dumache, R; Horhat, FG; Luca, L; Papurica, M; Popovici, SE; Rogobete, AF; Sandesc, D; Sarandan, M; Sima, LV; Vernic, C1
Chertoff, J1
Hou, L; Ji, G; Li, N; Li, S; Lu, Y; Ma, S; Peng, D; Qin, M; Shang, L; Xie, K; Xiong, L1
Rajapakse, S; Wijewickrama, ES1
Andrades, M; Dal-Pizzol, F; de Oliveira, MR; Fonseca Moreira, JC; Ritter, C; Streck, EL1
Cassol, OJ; Dal-Pizzol, F; Ferreira, GK; Gonçalves, CL; Petronilho, FC; Rezin, GT; Roesler, R; Scaini, G; Schwartsmann, G; Streck, EL1
Buaes, LE; Caberlon, E; Christ Vianna Santos, R; da Costa, VL; da Silva Melo, DA; da Silva Scherer, P; da Silva, GV; de Mello, RO; de Moraes, CM; de Oliveira, JR; Donadio, MV; Lunardelli, A; Nunes, FB1
Marsh, A; Myall, K; Sidney, J1
Sahoo, RK; Sharma, A1
Antunes, E; Casarin, AL; Lopes-Pires, ME; Lorand-Metze, I; Marcondes, S; Pereira-Cunha, FG1
Ayan, M; Cander, B; Erayman, I; Erdem, S; Girişgin, S; Gül, M; Seydanoğlu, A1
García, C; Martínez, M; Nicolás, M; Porta, R; Sánchez, L1
Andrade, L; Campos, R; Canale, D; de Bragança, AC; Lopes, FD; Olivo, C; Seguro, AC; Shimizu, MH; Volpini, RA1
Eisenhut, M1
Hauser, B; Radermacher, P; Szakmany, T1
Buwalda, M; Ince, C1
Galley, HF; Paterson, RL; Webster, NR1
Pinsky, MR1
Crouser, ED1
Andrades, M; Dal-Pizzol, F; Moreira, JC; Ritter, C1
Spapen, H1
Emet, S; Memis, D; Pamukçu, Z1
Diltoer, MW; Hendrickx, I; Huyghens, LP; Nguyen, DN; Spapen, HD1
Barreiro, E; Gáldiz, JB; Gea, J; Hussain, SN; Sánchez, D1
Atis, S; Bagdatoglu, O; Comelekoglu, U; Gunes, S; Nayci, A; Ozge, A1
Cross, CE; Halliwell, B; van Asbeck, BS1
Demiralay, R; Erdem, H; Gürsan, N1
Andrades, M; Bernard, EA; Dal-Pizzol, F; de Souza, LF; Moreira, JC; Pens Gelain, D; Ritter, C1
Kapiotis, S; Mittermayer, F; Pleiner, J; Posch, M; Schaller, G; Wolzt, M1
Barichello, T; Constantino, L; Dal-Pizzol, F; Machado, RA; Martins, MR; Petronilho, F; Quevedo, J; Réus, GZ; Ritter, C; Valvassori, SS1
Ghezzi, P; Villa, P1
Benlabed, M; Buurman, WA; Nguyen, DN; Spapen, H; Vincent, JL; Zhang, H1
Blackwell, TR; Blackwell, TS; Christman, BW; Christman, JW; Holden, EP1
Bernard, GR; Weikert, LF1
Fischer, JE; Hasselgren, PO; Hobler, SC; Monaco, J; Tiao, G1
Caputi, AP; Costantino, G; Cuzzocrea, S1
Ghezzi, P; Saccani, A; Sica, A; Villa, P1
Broner, CW; Hildner, WK; Shenep, JL; Stidham, GL; Stokes, DC1

Reviews

11 review(s) available for acetylcysteine and Blood Poisoning

ArticleYear
The role of ADAMTS-13 in the coagulopathy of sepsis.
    Journal of thrombosis and haemostasis : JTH, 2018, Volume: 16, Issue:4

    Topics: Acetylcysteine; ADAMTS13 Protein; Animals; Blood Coagulation; Humans; Recombinant Proteins; Sepsis; Substrate Specificity; Thrombotic Microangiopathies; von Willebrand Factor

2018
Sepsis: The Involvement of Platelets and the Current Treatments.
    Current molecular pharmacology, 2018, Volume: 11, Issue:4

    Topics: Acetylcysteine; Animals; Blood Platelets; Capsaicin; Chloroquine; Disseminated Intravascular Coagulation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-7; Platelet Aggregation Inhibitors; Sepsis; Software; Thrombocytopenia; Toll-Like Receptor 4

2018
[Severe toxic acute liver failure: etiology and treatment].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Anti-Infective Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Cholestasis; Combined Modality Therapy; Diagnosis, Differential; Disease Management; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Illicit Drugs; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Mushroom Poisoning; Neurologic Examination; Occupational Diseases; Respiratory Insufficiency; Sepsis; Shock; Time Factors; Valproic Acid

2013
Sepsis in the central nervous system and antioxidant strategies with N-acetylcysteine, vitamins and statins.
    Current neurovascular research, 2014, Volume: 11, Issue:1

    Topics: Acetylcysteine; Animals; Antioxidants; Central Nervous System; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Sepsis; Vitamins

2014
N-Acetylcysteine's Role in Sepsis and Potential Benefit in Patients With Microcirculatory Derangements.
    Journal of intensive care medicine, 2018, Volume: 33, Issue:2

    Topics: Acetylcysteine; Acidosis, Lactic; Free Radical Scavengers; Humans; Microcirculation; Mortality; Multiple Organ Failure; Regional Blood Flow; Sepsis; Vasodilation

2018
Non-dialytic management of sepsis-induced acute kidney injury.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2009, Volume: 20, Issue:6

    Topics: Acetylcysteine; Acute Disease; Contrast Media; Dopamine; Evidence-Based Medicine; Fluid Therapy; Humans; Hypoglycemic Agents; Insulin; Kidney Diseases; Osmotic Pressure; Perfusion; Risk Assessment; Risk Factors; Sepsis; Sodium Potassium Chloride Symporter Inhibitors; Treatment Outcome; Vasoconstrictor Agents

2009
Lack of toxicity after paracetamol overdose in a extremely preterm neonate.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:5

    Topics: Abdominal Pain; Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Free Radical Scavengers; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Medication Errors; Metabolic Clearance Rate; Sepsis; Treatment Outcome

2012
N-acetylcysteine for sepsis and systemic inflammatory response in adults.
    The Cochrane database of systematic reviews, 2012, Sep-12, Issue:9

    Topics: Acetylcysteine; Adult; Antioxidants; Humans; Injections, Intravenous; Randomized Controlled Trials as Topic; Sepsis; Systemic Inflammatory Response Syndrome; Treatment Outcome

2012
Opening the microcirculation: can vasodilators be useful in sepsis?
    Intensive care medicine, 2002, Volume: 28, Issue:9

    Topics: Acetylcysteine; Animals; Epoprostenol; Hemodynamics; Humans; Microcirculation; Netherlands; Nitric Oxide Donors; Oxygen; Pentoxifylline; Sepsis; Treatment Outcome; Vasodilator Agents

2002
Antioxidant therapy for severe sepsis: promise and perspective.
    Critical care medicine, 2003, Volume: 31, Issue:11

    Topics: Acetylcysteine; Antioxidants; Humans; NF-kappa B; Reproducibility of Results; Sepsis

2003
Pharmacotherapy of sepsis.
    Clinics in chest medicine, 1996, Volume: 17, Issue:2

    Topics: Acetylcysteine; Antioxidants; Bradykinin; Cyclooxygenase Inhibitors; Humans; Naloxone; Pentoxifylline; Platelet Activating Factor; Sepsis

1996

Trials

6 trial(s) available for acetylcysteine and Blood Poisoning

ArticleYear
Clinical Trial Assessment of Intermittent and Continuous Infusion Dose of N-Acetylcysteine on Redox Status of the Body in Patients with Sepsis Admitted to the ICU.
    Journal of intensive care medicine, 2020, Volume: 35, Issue:12

    Topics: Acetylcysteine; Humans; Infusions, Intravenous; Intensive Care Units; Oxidation-Reduction; Prospective Studies; Sepsis

2020
The immunological benefit of higher dose N-acetyl cysteine following mechanical ventilation in critically ill patients.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2014, Jul-15, Volume: 22

    Topics: Acetylcysteine; Adult; Antioxidants; APACHE; beta-Defensins; Creatinine; Critical Illness; Female; Glutathione; Humans; Immunoglobulin M; Intensive Care Units; Leukocyte Count; Male; Middle Aged; Multiple Trauma; Organ Dysfunction Scores; Respiration, Artificial; Sepsis; Young Adult

2014
The effect of N-acetylcysteine on nuclear factor-kappa B activation, interleukin-6, interleukin-8, and intercellular adhesion molecule-1 expression in patients with sepsis.
    Critical care medicine, 2003, Volume: 31, Issue:11

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Free Radical Scavengers; Humans; Infusions, Intravenous; Intercellular Adhesion Molecule-1; Interleukin-6; Interleukin-8; Male; Middle Aged; NF-kappa B; Sepsis

2003
The influence of N-acetyl-L-cystein infusion on cytokine levels and gastric intramucosal pH during severe sepsis.
    Critical care (London, England), 2004, Volume: 8, Issue:4

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Cytokines; Double-Blind Method; Female; Gastric Mucosa; Hemodynamics; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Monitoring, Physiologic; Oxidative Stress; Oxygen Consumption; Sepsis; Severity of Illness Index; Statistics, Nonparametric

2004
Effects of N-acetylcysteine on microalbuminuria and organ failure in acute severe sepsis: results of a pilot study.
    Chest, 2005, Volume: 127, Issue:4

    Topics: Acetylcysteine; Acute Disease; Adult; Aged; Aged, 80 and over; Albuminuria; Female; Humans; Male; Middle Aged; Multiple Organ Failure; Pilot Projects; Sepsis; Severity of Illness Index

2005
Effects of N-acetylcysteine against systemic and renal hemodynamic effects of endotoxin in healthy humans.
    Critical care medicine, 2007, Volume: 35, Issue:8

    Topics: Acetylcysteine; Adult; Blood Circulation; Cross-Over Studies; Cytokines; Dose-Response Relationship, Drug; Double-Blind Method; Free Radical Scavengers; Humans; Infusions, Intravenous; Interleukin-1beta; Lipopolysaccharides; Male; Oxidative Stress; Renal Circulation; Sepsis; Tumor Necrosis Factor-alpha

2007

Other Studies

39 other study(ies) available for acetylcysteine and Blood Poisoning

ArticleYear
Endothelial glycocalyx injury is involved in heatstroke-associated coagulopathy and protected by N-acetylcysteine.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Acetylcysteine; Animals; Blood Coagulation Disorders; Endothelial Cells; Glycocalyx; Heat Stroke; Hydrogen Peroxide; Rats; Reactive Oxygen Species; Retrospective Studies; Sepsis

2023
Gold nanoparticles potentiates N-acetylcysteine effects on neurochemicals alterations in rats after polymicrobial sepsis.
    Journal of drug targeting, 2020, Volume: 28, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Disease Models, Animal; Gold; Hippocampus; Inflammation; Male; Metal Nanoparticles; Mitochondria; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis

2020
Stratification to predict the response to antioxidant.
    Revista Brasileira de terapia intensiva, 2020, Volume: 32, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Animals; Antioxidants; Deferoxamine; Humans; Male; Middle Aged; Prognosis; Rats; Rats, Wistar; Retrospective Studies; Sepsis; Treatment Outcome

2020
Protective Effect of N-Acetylcysteine Pretreatment on Acute Kidney Injury in Septic Rats.
    The Journal of surgical research, 2020, Volume: 254

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cecum; Disease Models, Animal; Kidney; Ligation; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Sepsis

2020
Fulminant
    BMJ case reports, 2021, Jan-18, Volume: 14, Issue:1

    Topics: Acetylcysteine; Acidosis; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Arrhythmias, Cardiac; Bacillus cereus; Blood Coagulation Disorders; Blood Transfusion; Brain Diseases; Continuous Renal Replacement Therapy; Exotoxins; Fatal Outcome; Female; Foodborne Diseases; Free Radical Scavengers; Humans; Immunocompetence; Liver Failure; Multiple Organ Failure; Plasmapheresis; Renal Insufficiency; Rhabdomyolysis; Sepsis; Shock; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Whole Genome Sequencing

2021
PICK1 Deficiency Exacerbates Sepsis-Associated Acute Kidney Injury.
    BioMed research international, 2021, Volume: 2021

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; Carrier Proteins; Cell Cycle Proteins; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Kidney Tubules, Proximal; Lipopolysaccharides; Male; MAP Kinase Kinase Kinase 5; Mice, Inbred C57BL; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Peroxides; Sepsis

2021
Analysis of oxidative stress-related markers in critically ill polytrauma patients: An observational prospective single-center study.
    Bosnian journal of basic medical sciences, 2018, May-20, Volume: 18, Issue:2

    Topics: Acetylcysteine; Adult; Antioxidants; APACHE; Ascorbic Acid; Biomarkers; Critical Care; Critical Illness; Female; Humans; Inflammation; Lipid Peroxidation; Lipids; Male; Middle Aged; Multiple Trauma; Oxidative Stress; Partial Thromboplastin Time; Prospective Studies; Sepsis; Treatment Outcome

2018
Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress.
    Scientific reports, 2019, 01-14, Volume: 9, Issue:1

    Topics: Acetylcysteine; Anemia, Sickle Cell; Antioxidants; Biomarkers; Cysteine; Disulfides; Humans; Oxidative Stress; Sepsis

2019
N-acetylcysteine for sepsis and systemic inflammatory response in adults.
    Critical care nurse, 2013, Volume: 33, Issue:4

    Topics: Acetylcysteine; Critical Care; Humans; Sepsis; Systemic Inflammatory Response Syndrome

2013
Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway.
    Inflammation, 2015, Volume: 38, Issue:2

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; I-kappa B Kinase; I-kappa B Proteins; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mesangial Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Rats; Sepsis; Signal Transduction; Thioctic Acid; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2015
Intratracheal co-administration of antioxidants and ceftriaxone reduces pulmonary injury and mortality rate in an experimental model of sepsis.
    Respirology (Carlton, Vic.), 2014, Volume: 19, Issue:7

    Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Ceftriaxone; Disease Models, Animal; Drug Administration Routes; Drug Therapy, Combination; Lung Injury; Male; Rats; Rats, Wistar; Sepsis; Trachea; Vitamin E

2014
Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis.
    Scientific reports, 2015, Jul-22, Volume: 5

    Topics: Acetylcysteine; Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Line, Tumor; Down-Regulation; Epithelial Cells; Fas Ligand Protein; fas Receptor; Humans; Inflammation; Lipopolysaccharides; Lung; Mice; NF-kappa B; Reactive Oxygen Species; Respiratory Distress Syndrome; Sepsis; Serpins; Signal Transduction

2015
Modulation of the Redox Expression and Inflammation Response in the Critically Ill Polytrauma Patient with Thoracic Injury. Statistical Correlations between Antioxidant Therapy.
    Clinical laboratory, 2016, Sep-01, Volume: 62, Issue:9

    Topics: Abbreviated Injury Scale; Acetylcysteine; Adult; Aged; Antioxidants; Ascorbic Acid; Critical Illness; Female; Humans; Incidence; Inflammation; Injury Severity Score; Length of Stay; Male; Middle Aged; Multiple Organ Failure; Multiple Trauma; Oxidation-Reduction; Oxidative Stress; Respiration, Artificial; Retrospective Studies; Sepsis; Thiamine; Thoracic Injuries

2016
Effects of reactive oxygen species scavenger on the protective action of 100% oxygen treatment against sterile inflammation in mice.
    Shock (Augusta, Ga.), 2010, Volume: 33, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cytokines; Free Radical Scavengers; Heart; Inflammation; Kidney; Liver; Lung; Male; Mice; Multiple Organ Failure; Myocardium; Oxygen; Reactive Oxygen Species; Sepsis; Thiourea; Zymosan

2010
Antioxidant treatment reverses organ failure in rat model of sepsis: role of antioxidant enzymes imbalance, neutrophil infiltration, and oxidative stress.
    The Journal of surgical research, 2011, May-15, Volume: 167, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Catalase; Deferoxamine; Disease Models, Animal; Kidney; Lung; Male; Multiple Organ Failure; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sepsis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Urea

2011
Effects of N-acetylcysteine/deferoxamine, taurine and RC-3095 on respiratory chain complexes and creatine kinase activities in rat brain after sepsis.
    Neurochemical research, 2010, Volume: 35, Issue:4

    Topics: Acetylcysteine; Animals; Bombesin; Brain; Creatine Kinase; Deferoxamine; Electron Transport; Male; Peptide Fragments; Rats; Rats, Wistar; Sepsis; Taurine

2010
Effect of N-acetylcysteine and fructose-1,6-bisphosphate in the treatment of experimental sepsis.
    Inflammation, 2011, Volume: 34, Issue:6

    Topics: Acetylcysteine; Animals; Drug Synergism; Drug Therapy, Combination; Fructose-Bisphosphatase; Rats; Sepsis; Survival Rate; Treatment Outcome

2011
Mind the gap! An unusual metabolic acidosis.
    Lancet (London, England), 2011, Feb-05, Volume: 377, Issue:9764

    Topics: Acetaminophen; Acetylcysteine; Acidosis; Anti-Bacterial Agents; Antioxidants; Female; Floxacillin; Humans; Middle Aged; Pyrrolidonecarboxylic Acid; Sepsis; Sodium Bicarbonate

2011
Sinusoidal obstruction syndrome during induction therapy for acute lymphoblastic leukemia managed with N-acetyl Cysteine.
    Pediatric blood & cancer, 2011, Volume: 57, Issue:4

    Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Dexamethasone; Epirubicin; Female; Fibrinolytic Agents; Hepatic Veno-Occlusive Disease; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sepsis; Young Adult

2011
Lipopolysaccharide treatment reduces rat platelet aggregation independent of intracellular reactive-oxygen species generation.
    Platelets, 2012, Volume: 23, Issue:3

    Topics: Acetylcysteine; Adenosine Diphosphate; Animals; Blood Platelets; Free Radical Scavengers; Lipopolysaccharides; Male; Oxidation-Reduction; Platelet Aggregation; Rats; Rats, Wistar; Reactive Oxygen Species; Sepsis; Time Factors

2012
The effect of N-acetyl cysteine on serum glutathione, TNF-alpha and tissue malondialdehyde levels in the treatment of sepsis.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2011, Volume: 17, Issue:4

    Topics: Acetylcysteine; Animals; Female; Free Radical Scavengers; Glutathione; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sepsis; Tumor Necrosis Factor-alpha

2011
N-acetylcysteine prevents pulmonary edema and acute kidney injury in rats with sepsis submitted to mechanical ventilation.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Apr-01, Volume: 302, Issue:7

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Antioxidants; Cecum; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Lung; Male; Neutrophils; Oxidative Stress; Pulmonary Edema; Rats; Rats, Wistar; Respiration, Artificial; Sepsis; Sodium Channels; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2

2012
Role of nitric oxide metabolites in reduction of sodium potassium ATPase dependent pulmonary edema clearance.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Volume: 303, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Male; Pulmonary Edema; Respiration, Artificial; Sepsis

2012
Therapeutic benefits of antioxidants during sepsis: is protection against oxidant-mediated tissue damage only half the story?
    Critical care medicine, 2004, Volume: 32, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Deferoxamine; Free Radical Scavengers; Humans; Iron Chelating Agents; Oxidative Stress; Sepsis

2004
Antioxidants and sepsis: can we find the ideal approach?
    Critical care medicine, 2004, Volume: 32, Issue:6

    Topics: Acetylcysteine; Animals; Antioxidants; Humans; Iron; Sepsis; Swine

2004
N-acetylcysteine in clinical sepsis: a difficult marriage.
    Critical care (London, England), 2004, Volume: 8, Issue:4

    Topics: Acetylcysteine; Cytokines; Gastric Mucosa; Humans; Intensive Care Units; Oxidative Stress; Oxygen Consumption; Randomized Controlled Trials as Topic; Sepsis; Shock, Septic

2004
N-acetylcysteine increases manganese superoxide dismutase activity in septic rat diaphragms.
    The European respiratory journal, 2005, Volume: 26, Issue:6

    Topics: Acetylcysteine; Analysis of Variance; Animals; Biopsy, Needle; Diaphragm; Disease Models, Animal; Immunohistochemistry; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Sepsis; Superoxide Dismutase

2005
N-acetylcysteine protects the rats against phrenic nerve dysfunction in sepsis.
    Shock (Augusta, Ga.), 2006, Volume: 25, Issue:1

    Topics: Acetylcysteine; Animals; Catalase; Electromyography; Malondialdehyde; Nitrates; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxidase; Phrenic Nerve; Rats; Rats, Wistar; Sepsis

2006
More antioxidants in sepsis: still paved with uncertainties.
    Critical care medicine, 2006, Volume: 34, Issue:2

    Topics: Acetylcysteine; Animals; Bronchoalveolar Lavage Fluid; Deferoxamine; Disease Models, Animal; Humans; Oxidation-Reduction; Oxidative Stress; Respiratory Distress Syndrome; Sepsis; Siderophores

2006
Regulation of sepsis-induced apoptosis of pulmonary cells by posttreatment of erdosteine and N-aceylcysteine.
    Toxicology, 2006, Dec-07, Volume: 228, Issue:2-3

    Topics: Acetylcysteine; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; Free Radical Scavengers; Immunohistochemistry; In Situ Nick-End Labeling; Lipopolysaccharides; Lung; Peroxidase; Pneumonia; Rats; Rats, Wistar; Sepsis; Thioglycolates; Thiophenes; Tissue Embedding; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2006
Mitochondrial superoxide production is related to the control of cytokine release from peritoneal macrophage after antioxidant treatment in septic rats.
    The Journal of surgical research, 2007, Volume: 141, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Cytokines; Deferoxamine; Macrophages, Peritoneal; Male; Mitochondria; Rats; Rats, Wistar; Sepsis; Signal Transduction; Superoxides; Thiobarbituric Acid Reactive Substances

2007
Antioxidant treatment prevented late memory impairment in an animal model of sepsis.
    Critical care medicine, 2007, Volume: 35, Issue:9

    Topics: Acetylcysteine; Animals; Antioxidants; Avoidance Learning; Cecum; Deferoxamine; Disease Models, Animal; Habituation, Psychophysiologic; Intestinal Perforation; Ligation; Male; Memory Disorders; Rats; Rats, Wistar; Sepsis

2007
Effect of N-acetyl-L-cysteine on sepsis in mice.
    European journal of pharmacology, 1995, Mar-16, Volume: 292, Issue:3-4

    Topics: Acetylcysteine; Allopurinol; Animals; Cecum; Free Radical Scavengers; Free Radicals; Glutathione; Liver; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Oxidative Stress; Sepsis; Tumor Necrosis Factor-alpha; Xanthine Oxidase

1995
Protective effects of N-acetyl-L-cysteine in endotoxemia.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: Acetylcysteine; Animals; Blood Pressure; Cardiac Tamponade; Dogs; Endotoxins; Escherichia coli; Female; Heart Rate; Hematocrit; Hemodynamics; Lactates; Male; Oxygen Consumption; Pulmonary Artery; Pulmonary Circulation; Sepsis; Stroke Volume; Time Factors; Vascular Resistance; Ventricular Function, Left; Ventricular Function, Right

1994
In vivo antioxidant treatment suppresses nuclear factor-kappa B activation and neutrophilic lung inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Aug-15, Volume: 157, Issue:4

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Base Sequence; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Dinoprost; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; F2-Isoprostanes; Gene Expression Regulation; Glutathione; Growth Substances; Inflammation; Intercellular Signaling Peptides and Proteins; Leukocyte Count; Lung; Lung Diseases; Male; Molecular Sequence Data; Neutrophils; NF-kappa B; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; RNA, Messenger; Sepsis

1996
Sepsis-induced increase in muscle proteolysis is blocked by specific proteasome inhibitors.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Acetylcysteine; Animals; Cecum; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dactinomycin; Kinetics; Leupeptins; Male; Multienzyme Complexes; Muscle Proteins; Muscle, Skeletal; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sepsis; Transcription, Genetic; Ubiquitins

1998
Protective effect of N-acetylcysteine on cellular energy depletion in a non-septic shock model induced by zymosan in the rat.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:2

    Topics: Acetylcysteine; Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Energy Metabolism; Free Radical Scavengers; Macrophages, Peritoneal; Male; NAD; Nitrates; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Shock; Tyrosine; Zymosan

1999
Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense.
    The Journal of infectious diseases, 2002, Apr-15, Volume: 185, Issue:8

    Topics: Acetylcysteine; Animals; Cell Movement; Chemokines; Glutathione; Immunity, Innate; Inflammation; Male; Mice; Mice, Inbred ICR; Neutrophils; Sepsis

2002
Effect of scavengers of oxygen-derived free radicals on mortality in endotoxin-challenged mice.
    Critical care medicine, 1988, Volume: 16, Issue:9

    Topics: Acetylcysteine; Animals; Endotoxins; Escherichia coli; Female; Free Radicals; Mice; Mice, Inbred Strains; Sepsis; Superoxide Dismutase

1988