acetylcysteine and Benign Neoplasms

acetylcysteine has been researched along with Benign Neoplasms in 103 studies

Research

Studies (103)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (5.83)	18.7374
1990's	8 (7.77)	18.2507
2000's	39 (37.86)	29.6817
2010's	42 (40.78)	24.3611
2020's	8 (7.77)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L	1
Collado, JA; Delgado, G; Egas, V; Méndez-Cuesta, CA; Millán, E; Muñoz, E; Ramírez-Apan, T	1
Dong, YL; Hu, TX; Huo, JF; Ke, Y; Li, LL; Li, YF; Liu, HM; Liu, XJ; Wang, C; Zhang, XY; Zhao, JZ	1
Awasthi, S; Garg, R; Horne, D; Salgia, R; Singhal, S; Singhal, SS	1
Cai, C; Han, Y; He, X; Hu, X; Kang, H; Liu, S; Liu, Y; Ma, X; Pan, T; Qi, J; Tang, Y; Wu, D; Yao, Y; Zhang, Z; Zhou, M	1
Chi, YY; Eisenberg, LS; Freyer, DR; Knight, KR; Malvar, J; Mena, V; Muldoon, LL; Neely, M; Neuwelt, EA; Orgel, E; Rassekh, SR; Ross, CJD; Rushing, T; Scott, EN	1
Borges, ID; Kenari, F; Molnár, S; Napolitano, HB; Perjési, P	1
Lugli, E; Pilipow, K; Scamardella, E	1
Duconge, J; Gonzalez, MJ; Minich, DM; Morales-Borges, RH	1
Büyük, B; Coşkun, Ö; Öztopuz, Ö	1
Chen, X; Miao, X; Wen, H; Yin, S; Zhang, X	1
Choi, YJ; Lee, J; Lee, YS; Park, WY; Seo, SW; Shim, DM	1
Baccarelli, AA; Bartolucci, GB; Byun, HM; Carrieri, M; Guo, L; Jiménez-Garza, O; Zhong, J	1
Butera, G; Butturini, E; Caraglia, M; Cavallini, C; Coan, M; Cordani, M; Dando, I; Donadelli, M; Gaidano, G; Gasperini, S; Mariotto, S; Nadal-Serrano, M; Oliver, J; Oppici, E; Pacchiana, R; Roca, P; Rossi, D; Scupoli, MT; Spizzo, R; Tamassia, N; Torrens-Mas, M	1
Juránek, I; Rapta, P; Šoltés, L; Valachová, K; Valent, I	1
Cho, SG; Im, KI; Jeon, YW; Kim, N; Lee, ES; Lim, JY; Nam, YS; Song, Y	1
Belcastro, E; Bussolati, O; Chiu, M; Corti, A; Dominici, S; Pacini, S; Piaggi, S; Pompella, A; Taurino, G	1
Crump, A; Ōmura, S	1
Acar, HY; Ari, F; Buz, PT; Demirci, G; Duman, FD; Erkisa, M; Ulukaya, E	1
Bollinger, J; Budhraja, A; Craig, J; Lang, WH; Ling, T; Maier, J; Marsico, TD; Opferman, J; Potts, MB; Rivas, F	1
Brock, P; Cabral, S; Freyer, DR; Knight, K; Reaman, G; Robinson, PD; Sung, L	1
Basile, A; Mazzone, A; Morello, S; Pellecchia, C; Strianese, M; Turco, MC	1
Hanly, L; Huang, SH; Koren, G; Regueira, O; Rieder, MJ; Shah, RK; Vasylyeva, TL	1
Amoscato, A; Celis, E; Condamine, T; Gabrilovich, DI; Johnson, JJ; Kagan, VE; Klein-Seetharaman, J; Mohammadyani, D; Ramakrishnan, R; Tuyrin, VA; Tyurin, VA; Veglia, F; Zhang, LM	1
Gutierrez, E; Jansson, PJ; Richardson, DR	1
Hua, Y; Xie, AM; Yuan, J; Zhang, W; Zhu, HY; Zhu, JP	1
Krivitsky, A; Polyak, D; Satchi-Fainaro, R; Scomparin, A	1
Cai, S; Gao, Y; Qu, L; She, T; Shou, C; Su, Y; Wang, L; Xu, S; Zhao, C	1
Bjørn, ME; Hasselbalch, HC	1
Butterworth, KT; Currell, FJ; McMahon, SJ; Prise, KM; Schettino, G; Taggart, LE	1
Cheng, WH; Gong, MY; Liu, XX; Wang, YN; You, H; Zhang, X; Zhu, JH; Zhu, JJ; Zou, M	1
Akao, Y; Kumazaki, M; Kuranaga, Y; Shinohara, H; Sugito, N; Takai, T; Taniguchi, K	1
Aldinucci, D; Altaf, M; Borghese, C; Casagrande, N; Celegato, M; Corona, G; Isab, AA; Kawde, AN; Larcher, R; Monim-Ul-Mehboob, M; Ogasawara, M; Siddik, ZH	1
Abdel-Qadir, H; Amir, E; Fazelzad, R; Lee, DS; Ong, G; Thavendiranathan, P; Tomlinson, G	1
Chen, D; Dou, QP; Landis-Piwowar, KR; Milacic, V; Yang, H	1
Amantini, C; Bramucci, M; Buonanno, F; Iio, H; Lucciarini, R; Ortenzi, C; Quassinti, L; Santoni, G	1
Berg, JZ; Hecht, SS; Hochalter, JB	1
Tsukamoto, S; Yokosawa, H	1
Millea, PJ	1
Gu, H; Guo, Q; Liu, W; Lu, N; Mu, R; Qi, Q; Rong, J; Wang, J; Yang, Y; You, Q	1
Cavalieri, EL; Rogan, EG	1
Bulut, D; Chromik, AM; Daigeler, A; Flier, A; Hahn, SA; Harati, K; May, C; Mittelkötter, U; Ritter, PR; Roschinsky, J; Sülberg, D; Uhl, W	1
Benbrook, DM; Ding, WQ; Hanigan, MH; Lind, SE; Lou, JR; Zhang, XX; Zheng, J	1
Filatova, NA; Gamaleĭ, IA; Kirpichnikova, KM; Vakhromova, EA	1
Dai, XM; Gao, J; Guo, WJ; Li, WB; Liu, HL; Wang, CH; Xu, JJ; Yao, QZ	1
Du, J; King, I; Nassar, AE	1
Bershteĭn, LM; Boiarkina, MP; Kovalenko, IG; Kovalevskiĭ, AIu; Poroshina, TE; Revskoĭ, SIu; Vasil'ev, DA	1
Akitaya, T; Kamiie, K; Kidachi, Y; Noshita, T; Ryoyama, K; Umetsu, H; Yamaguchi, H; Yoshida, K; Yu, T	1
Dozias, S; Gosset, D; Kieda, C; Legrain, B; Lerondel, S; Pape, AL; Pouvesle, JM; Ries, D; Robert, E; Sarron, V; Sobilo, J; Vandamme, M	1
Cramer, JM; Jeffery, EH; Teran-Garcia, M	1
Gu, W; Silverman, RB	1
Alladin, KP; Igbokwe, O; Nakayama, A; White, JD	1
Awasthi, S; Awasthi, YC; Chaudhary, P; Kokate, RA; Kumar, S; Sahu, M; Sharma, R	1
Achilefu, S; Akers, W; Cao, J; Deng, DW; Gu, YQ; Li, X; Liu, F; Xue, B	1
Costanzo, C; Dalla Pozza, E; Dando, I; Donadelli, M; Fiorini, C; Menegazzi, M; Palmieri, M; Sgarbossa, A	1
Ávalos Fúnez, A; Isabel Haza, A; Mateo, D; Morales, P	1
Choi, YK; Kim, DG; Liu, MJ; Won, YS; You, KR	1
Boehncke, WH; Elliott, PJ; Zollner, TM	1
Bae, GU; Cho, EJ; Choi, WS; Han, JW; Han, SH; Jung, DK; Kang, H; Kim, YK; Lee, HW; Lee, HY; Seo, DW	1
Harris, RC; Singh, AB	1
Chiao, JW; Chung, FL; Conaway, CC; Liu, D; Ramaswamy, G; Wang, L; Wu, H	1
Yildiz, D	1
Barrett, JC; French, JE; Honeycutt, HP; Jokinen, MP; Kari, FW; Martin, KR; Quinn, A	1
Goto, R; Ibuki, Y	1
Beckett, MA; Hellman, S; Kimchi, ET; Kufe, DW; Lopez, CA; Mauceri, HJ; Mehta, N; Murphy, KT; Park, JO; Posner, MC; Weichselbaum, RR	1
Daniel, KG; Dou, QP; Kazi, A; Kuhn, DJ	1
Aitio, ML	1
Albertsson, P; Lennernäs, B; Norrby, K	1
Balansky, R; Croce, CM; D'Agostini, F; De Flora, S; Di Marco, B; Ganchev, G; Izzotti, A; Lubet, RA; Zanesi, N	1
Matkovics, A	1
Hemann, CF; Hille, R; Horan, MP; Mallery, SR; Pei, P; Schwendeman, SP	1
Awasthi, S; Singhal, SS; Yadav, S; Zajac, E	1
Khashab, M; Kwo, PY; Tector, AJ	1
Chesselet, MF; Fleming, SM; Reliene, R; Schiestl, RH	1
Barkholt, L; Brune, M; Fransson, K; Hassan, M; Hassan, Z; Karlsson, H; Mattsson, J; Omazic, B; Remberger, M; Ringdén, O; Svahn, BM	1
Ishimi, Y; Takezawa, J; Yamada, K	1
Bauer, JA; Belbin, TJ; Bradford, CR; Brenner, JC; Carey, TE; Prystowsky, MB; Sikora, MJ; Soengas, MS; Taylor, JC; Verhaegen, M; Wang, S	1
Hecht, SS; Hochalter, JB; Villalta, PW	1
Bonow, R; Corden, B; Doroshow, J; Epstein, S; Jenkins, J; Locker, G; Myers, C; Palmeri, S	1
Muggia, FM	1
Anderson, T; Duelge, J; Hansen, RM; Holoye, PY; Ritch, PS	1
Alberts, DS; Boone, CW; Covey, JM; Crowell, JA; Doody, LA; Greenwald, P; Kelloff, GJ; Knapp, GG; Lubet, RA; Steele, VE	1
Balansky, RM; D'Agostini, F; De Flora, S; Izzotti, A; Rossi, GA	1
Feldstein, TJ; Hartfield, D; Horner, H; Kobrinsky, NL; Maksymiuk, A; Minuk, GY; White, DF	1
Aeschbacher, B; Fikrle, A; Fluri, M; Meier, B; Wagdi, P	1
Bockstette, M; Dröge, W; Galter, D; Gross, A; Hack, V; Kinscherf, R; Mihm, S; Schykowski, M	1
Bärtsch, P; Benner, A; Breitkreutz, R; Dröge, W; Hack, V; Kinscherf, R; Röhrer, H; Taut, F	1
Clarke, DM; Loo, TW	1
Macciò, A; Mantovani, G; Massa, E; Melis, G; Mudu, MC; Mura, L	1
An, WG; Blagosklonny, MV; Hwang, SG; Trepel, JB	1
Ashok, BT; Kim, E; Mittelman, A; Tiwari, RK	1
Elliott, PJ; Ross, JS	1
Moyad, MA	1
Albini, A; De Flora, S; Ferrari, N; Tosetti, F	1
Baas, P; Balm, AJ; Bast, A; Besarati Nia, A; Besaratinia, A; Camoirano, A; D'Agostini, F; Dallinga, JW; De Flora, S; Haenen, GR; Izzotti, A; Sakai, H; Van Schooten, FJ; Van Zandwijk, N; Van't Veer, L	1
Brash, DE; Havre, PA; McCormick, JJ; O'Reilly, S	1
Reboud-Ravaux, M	1
Domingo, P; Martinez, E	1
Bodey, GP; Ho, DH; LeBlanc, B; Rolston, KV	1
Schreiber, EC	1

Reviews

26 review(s) available for acetylcysteine and Benign Neoplasms

Article	Year
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nature cell biology, 2015, Volume: 17, Issue:11 Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction	2015
RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling. Biochimica et biophysica acta. Reviews on cancer, 2022, Volume: 1877, Issue:5 Topics: Acetylcysteine; Adipokines; Animals; Carcinogenesis; Carcinogens; Carrier Proteins; Clathrin; Cytokines; Epidermal Growth Factor; GTPase-Activating Proteins; Humans; Infant; Insulins; Male; Mice; Neoplasms; Obesity; Oxidative Stress; Peptide Hormones; Transforming Growth Factor beta; Tumor Suppressor Protein p53	2022
N-Acetyl Cysteine and Glutathione in Health and Cancer-Pharmacogenomics, Research, and Clinical Practice: Hypothesis and Review. Alternative therapies in health and medicine, 2022, Volume: 28, Issue:7 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Glutathione; Humans; Neoplasms; Pharmacogenetics; Sulfhydryl Compounds	2022
Lactacystin: first-in-class proteasome inhibitor still excelling and an exemplar for future antibiotic research. The Journal of antibiotics, 2019, Volume: 72, Issue:4 Topics: Acetylcysteine; Antibiotics, Antineoplastic; Biological Products; Dementia; Drug Discovery; Humans; Neoplasms; Neuroprotective Agents; Proteasome Inhibitors	2019
Interventions for cisplatin-induced hearing loss in children and adolescents with cancer. The Lancet. Child & adolescent health, 2019, Volume: 3, Issue:8 Topics: Acetylcysteine; Adolescent; Amifostine; Anti-Inflammatory Agents; Antineoplastic Agents; Chelating Agents; Child; Cisplatin; Cytoprotection; Dexamethasone; Disulfiram; Ditiocarb; Humans; Neoplasms; Ototoxicity; Thiosulfates	2019
Achieving successful delivery of oligonucleotides--From physico-chemical characterization to in vivo evaluation. Biotechnology advances, 2015, Nov-01, Volume: 33, Issue:6 Pt 3 Topics: Acetylcysteine; Animals; Dendrimers; Drug Delivery Systems; Drug Evaluation, Preclinical; Hepatitis; HIV Infections; Humans; MicroRNAs; Microscopy; Neoplasms; Neurodegenerative Diseases; Oligonucleotides; RNA Interference; Static Electricity	2015
The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms. Mediators of inflammation, 2015, Volume: 2015 Topics: Acetylcysteine; Animals; Antioxidants; Disease Progression; Hepatitis C; Humans; Inflammation; Mice; Myeloproliferative Disorders; Neoplasms; Oxidative Stress; Primary Myelofibrosis; Reactive Oxygen Species; Signal Transduction	2015
Interventions for preventing cardiomyopathy due to anthracyclines: a Bayesian network meta-analysis. Annals of oncology : official journal of the European Society for Medical Oncology, 2017, 03-01, Volume: 28, Issue:3 Topics: Acetylcysteine; Adrenergic beta-Antagonists; Angiotensins; Anthracyclines; Cardiomyopathies; Clinical Trials as Topic; Dexrazoxane; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Neoplasms; Network Meta-Analysis; Prenylamine; Ventricular Dysfunction, Left	2017
Natural compounds with proteasome inhibitory activity for cancer prevention and treatment. Current protein & peptide science, 2008, Volume: 9, Issue:3 Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Boronic Acids; Bortezomib; Clinical Trials as Topic; Curcumin; Humans; Neoplasms; Pentacyclic Triterpenes; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Triterpenes; Ubiquitin	2008
Targeting the proteasome pathway. Expert opinion on therapeutic targets, 2009, Volume: 13, Issue:5 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Biological Products; Boronic Acids; Bortezomib; Drug Delivery Systems; Drug Discovery; Humans; Lactones; Neoplasms; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Ubiquitin; Ubiquitin-Activating Enzymes; Ubiquitins	2009
N-acetylcysteine: multiple clinical applications. American family physician, 2009, Aug-01, Volume: 80, Issue:3 Topics: Acetaminophen; Acetylcysteine; Antidotes; Expectorants; Female; Free Radical Scavengers; Hearing Loss; Humans; Influenza, Human; Neoplasms; Polycystic Ovary Syndrome; Respiratory Tract Diseases	2009
Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers. Future oncology (London, England), 2010, Volume: 6, Issue:1 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; DNA Adducts; Estrogens; Female; Humans; Male; Neoplasms; Resveratrol; Stilbenes	2010
Systematic review: generating evidence-based guidelines on the concurrent use of dietary antioxidants and chemotherapy or radiotherapy. Cancer investigation, 2011, Volume: 29, Issue:10 Topics: Acetylcysteine; Antioxidants; Evidence-Based Practice; Glutathione; Humans; Neoplasms; Practice Guidelines as Topic; Vitamin E	2011
Inhibition of mercapturic acid pathway-mediated disposal of 4-hydroxynonenal causes complete and sustained remission of human cancer xenografts in nude mice. Indian journal of experimental biology, 2011, Volume: 49, Issue:11 Topics: Acetylcysteine; Aldehydes; Animals; ATP-Binding Cassette Transporters; Carcinogens, Environmental; Chemoprevention; Glutathione Transferase; GTPase-Activating Proteins; Humans; Metabolic Networks and Pathways; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Remission Induction; Xenobiotics	2011
Proteasome inhibition: a new anti-inflammatory strategy. Journal of molecular medicine (Berlin, Germany), 2003, Volume: 81, Issue:4 Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Asthma; Boronic Acids; Bortezomib; Clinical Trials as Topic; Cysteine Endopeptidases; Disease Models, Animal; Humans; Inflammation; Lysine; Models, Biological; Models, Chemical; Multienzyme Complexes; Multiple Sclerosis; Neoplasms; NF-kappa B; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Psoriasis; Pyrazines; Reperfusion Injury	2003
Anti-angiogenic and anti-tumor properties of proteasome inhibitors. Current cancer drug targets, 2005, Volume: 5, Issue:7 Topics: Acetylcysteine; Angiogenesis Inhibitors; Antineoplastic Agents; Boronic Acids; Bortezomib; Humans; Neoplasms; Neovascularization, Pathologic; Protease Inhibitors; Proteasome Inhibitors; Pyrazines	2005
N-acetylcysteine -- passe-partout or much ado about nothing? British journal of clinical pharmacology, 2006, Volume: 61, Issue:1 Topics: Acetylcysteine; Anti-HIV Agents; Antioxidants; Cardiovascular Diseases; Drug Therapy, Combination; Expectorants; HIV Infections; Humans; Kidney Diseases; Liver Diseases; Lung Diseases; Neoplasms; Oxidative Stress; Reactive Oxygen Species	2006
[Recent changes in concepts of antioxidant treatment]. Orvosi hetilap, 2006, Apr-23, Volume: 147, Issue:16 Topics: Acetylcysteine; Allopurinol; Antioxidants; Apoptosis; Ascorbic Acid; Cardiovascular Diseases; Clinical Trials as Topic; Coenzymes; Flavonoids; Humans; Meta-Analysis as Topic; Neoplasms; Selenium; Ubiquinone; Vitamin A; Vitamin D; Vitamin E; Vitamin K; Vitamins	2006
Linking stress-signaling, glutathione metabolism, signaling pathways and xenobiotic transporters. Cancer metastasis reviews, 2007, Volume: 26, Issue:1 Topics: Acetylcysteine; ATP-Binding Cassette Transporters; Drug Resistance, Neoplasm; Endocytosis; Glutathione; GTPase-Activating Proteins; Humans; Lipid Peroxidation; Neoplasms; Radiation Protection; Signal Transduction	2007
Epidemiology of acute liver failure. Current gastroenterology reports, 2007, Volume: 9, Issue:1 Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug-Related Side Effects and Adverse Reactions; Free Radical Scavengers; Hepatitis, Autoimmune; Hepatitis, Viral, Human; Humans; Liver Failure, Acute; Liver Transplantation; Metabolic Diseases; Neoplasms; Prognosis; Vascular Diseases	2007
Role of cysteine and glutathione in HIV infection and cancer cachexia: therapeutic intervention with N-acetylcysteine. Advances in pharmacology (San Diego, Calif.), 1997, Volume: 38 Topics: Acetylcysteine; Amino Acids; Cachexia; Cysteine; Glutathione; HIV Infections; Humans; Muscle, Skeletal; Neoplasms	1997
The proteasome: a new target for novel drug therapies. American journal of clinical pathology, 2001, Volume: 116, Issue:5 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Carcinoma, Lewis Lung; Clinical Trials, Phase I as Topic; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Disease Models, Animal; Humans; Multienzyme Complexes; Neoplasms; Proteasome Endopeptidase Complex; Pyrazines	2001
Results and lessons from clinical trials using dietary supplements for cancer: direct and indirect investigations. Seminars in urologic oncology, 2001, Volume: 19, Issue:4 Topics: Acetylcysteine; Amygdalin; Antioxidants; Ascorbic Acid; beta Carotene; Dietary Supplements; Disease Progression; Humans; Neoplasms; Randomized Controlled Trials as Topic; Selenium; Tissue Extracts; Vitamin A; Vitamin E	2001
Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:1 Topics: Acetylcysteine; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Catechin; Flavonoids; Humans; Models, Biological; Neoplasms; Neovascularization, Pathologic; Protease Inhibitors; Receptors, Cytoplasmic and Nuclear	2002
Proteasome inhibitors. Progress in molecular and subcellular biology, 2002, Volume: 29 Topics: Acetylcysteine; Animals; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Design; Humans; Hydrolysis; Inflammation; Isocoumarins; Macromolecular Substances; Molecular Weight; Multienzyme Complexes; Neoplasms; Peptides; Proteasome Endopeptidase Complex; Substrate Specificity	2002
Metabolically oxygenated compounds: formation, conjugation, and possible biological implications. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:8 Topics: Acetylcysteine; Alcohols; Animals; Biotransformation; Ethers, Cyclic; Glucuronates; Half-Life; Humans; Hydro-Lyases; Hydroxylation; Mixed Function Oxygenases; Morphine; Mutation; Neoplasms; Nitrogen; Oxides; Oxygen Consumption; Oxygenases; Pharmaceutical Preparations; Phenols; Phenylacetates; Species Specificity; Sulfates; Uracil Nucleotides	1974

Trials

10 trial(s) available for acetylcysteine and Benign Neoplasms

Article	Year
Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation. American journal of hematology, 2023, Volume: 98, Issue:6 Topics: Acetylcysteine; Behavior Therapy; Busulfan; Decitabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Myeloproliferative Disorders; Neoplasms; Prospective Studies; Reactive Oxygen Species; Transplantation Conditioning	2023
Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial. Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, 07-05, Volume: 29, Issue:13 Topics: Acetylcysteine; Administration, Intravenous; Adolescent; Child; Cisplatin; Hearing Loss; Humans; Neoplasms	2023
[Influence of metformin and N-acetylcysteine on hormonal and genotoxic effects of estrogens and glucose in convalescent cancer patients]. Voprosy onkologii, 2010, Volume: 56, Issue:6 Topics: Acetylcysteine; Aged; Blood Glucose; Body Mass Index; Breast Neoplasms; Colonic Neoplasms; Drug Administration Schedule; Endometrial Neoplasms; Estrogens; Female; Free Radical Scavengers; Glucose; Humans; Hypoglycemic Agents; Interleukin-6; Metformin; Middle Aged; Neoplasms; Postmenopause; Treatment Outcome; Tumor Necrosis Factor-alpha	2010
Enhancing sulforaphane absorption and excretion in healthy men through the combined consumption of fresh broccoli sprouts and a glucoraphanin-rich powder. The British journal of nutrition, 2012, Volume: 107, Issue:9 Topics: Absorption; Acetylcysteine; Adolescent; Adult; Anticarcinogenic Agents; Biomarkers; Brassica; Cross-Over Studies; Diet; Dietary Supplements; Glucosinolates; Humans; Hydrolysis; Imidoesters; Isothiocyanates; Male; Neoplasms; Nutritional Sciences; Oximes; Powders; Sulfoxides; Surveys and Questionnaires; Young Adult	2012
A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation. Bone marrow transplantation, 2008, Volume: 41, Issue:9 Topics: Acetylcysteine; Adolescent; Adult; Aged; Aspartate Aminotransferases; Bilirubin; Child; Child, Preschool; Female; Free Radical Scavengers; Hematopoietic Stem Cell Transplantation; Hepatic Veno-Occlusive Disease; Humans; Male; Middle Aged; Neoplasms; Prospective Studies; Time Factors; Transplantation, Homologous	2008
A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine. Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1 Topics: Acetylcysteine; Adolescent; Adult; Aged; Cardiomyopathies; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Patient Compliance; Random Allocation; Stroke Volume	1983
Treatment of advanced malignancies with high-dose acetaminophen and N-acetylcysteine rescue. Cancer investigation, 1996, Volume: 14, Issue:3 Topics: Acetaminophen; Acetylcysteine; Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Drug Combinations; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Time Factors	1996
Cardioprotection in patients undergoing chemo- and/or radiotherapy for neoplastic disease. A pilot study. Japanese heart journal, 1996, Volume: 37, Issue:3 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Double-Blind Method; Heart; Humans; Neoplasms; Pilot Projects; Prospective Studies; Radionuclide Ventriculography; Radiotherapy; Radiotherapy Dosage; Stroke Volume; Vitamin E	1996
The redox state as a correlate of senescence and wasting and as a target for therapeutic intervention. Blood, 1998, Jul-01, Volume: 92, Issue:1 Topics: Acetylcysteine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Cell Death; Child; Child, Preschool; Cystine; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Neoplasms; Oxidation-Reduction; Serum Albumin; Sulfhydryl Compounds	1998
Effects of oral administration of N-acetyl-L-cysteine: a multi-biomarker study in smokers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:2 Topics: Acetylcysteine; Administration, Oral; Adult; Anticarcinogenic Agents; Antioxidants; Biomarkers; Cotinine; DNA Adducts; DNA Damage; Double-Blind Method; Female; Free Radical Scavengers; Humans; Male; Mutagenicity Tests; Neoplasms; Smoking	2002

Other Studies

67 other study(ies) available for acetylcysteine and Benign Neoplasms

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Effect of natural and semi-synthetic cadinanes from Heterotheca inuloides on NF-κB, Nrf2 and STAT3 signaling pathways and evaluation of their in vitro cytotoxicity in human cancer cell lines. Bioorganic & medicinal chemistry, 2017, 06-15, Volume: 25, Issue:12 Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Asteraceae; Cell Line, Tumor; Cell Proliferation; Humans; Inflammation; Molecular Docking Simulation; Neoplasms; NF-E2-Related Factor 2; NF-kappa B; Polycyclic Sesquiterpenes; Sesquiterpenes; Signal Transduction; STAT3 Transcription Factor	2017
Synthesis and in vitro and in vivo biological evaluation of novel derivatives of flexicaulin A as antiproliferative agents. European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; Female; Humans; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mitochondria; Molecular Structure; Neoplasms; Reactive Oxygen Species; Structure-Activity Relationship; Xenograft Model Antitumor Assays	2020
( International journal of molecular sciences, 2023, May-10, Volume: 24, Issue:10 Topics: Acetylcysteine; Antineoplastic Agents; Chalcone; Chalcones; Chromatography, High Pressure Liquid; Glutathione; Neoplasms; Sulfhydryl Compounds	2023
Generating stem-like memory T cells with antioxidants for adoptive cell transfer immunotherapy of cancer. Methods in enzymology, 2020, Volume: 631 Topics: Acetylcysteine; Antioxidants; CD8-Positive T-Lymphocytes; Cytotoxicity Tests, Immunologic; Humans; Immunologic Memory; Immunotherapy, Adoptive; Neoplasms; Stem Cells	2020
Possible protective activity of n-acetyl cysteine against cisplatin‑induced hepatotoxicity in rats. Molecular biology reports, 2021, Volume: 48, Issue:1 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Chemical and Drug Induced Liver Injury; Cisplatin; Humans; Inflammation; Liver; Neoplasms; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar	2021
Environmental temperature affects physiology and survival of nanosecond pulsed electric field-treated cells. Journal of cellular physiology, 2018, Volume: 233, Issue:2 Topics: Ablation Techniques; Acetylcysteine; Animals; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Separation; Cell Survival; Centrifugation; Electric Stimulation; Flow Cytometry; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Neoplasms; Reactive Oxygen Species; Sucrose; Temperature; Time Factors	2018
TP53 alteration determines the combinational cytotoxic effect of doxorubicin and an antioxidant NAC. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:6 Topics: A549 Cells; Acetylcysteine; Antioxidants; Apoptosis; Cell Proliferation; Doxorubicin; Drug Synergism; Heart Failure; Humans; MCF-7 Cells; Neoplasms; Phosphorylation; Reactive Oxygen Species; Tumor Suppressor Protein p53	2017
Promoter methylation status in genes related with inflammation, nitrosative stress and xenobiotic metabolism in low-level benzene exposure: Searching for biomarkers of oncogenesis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017, Volume: 109, Issue:Pt 1 Topics: Acetylcysteine; Adult; Benzene; Biomarkers; Carcinogenesis; Cytochrome P-450 CYP2E1; DNA Methylation; Epigenesis, Genetic; Female; Humans; Inflammation; Inhalation Exposure; Interleukin-6; Male; Middle Aged; Neoplasms; Nitrosative Stress; Promoter Regions, Genetic; Xenobiotics; Young Adult	2017
Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O British journal of cancer, 2018, Volume: 119, Issue:8 Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; AMP-Activated Protein Kinases; Cell Line, Tumor; Female; Free Radical Scavengers; Heat-Shock Proteins; Humans; Male; MCF-7 Cells; Middle Aged; Mitochondria; Neoplasms; Oxygen; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Tumor Suppressor Protein p53; Uncoupling Protein 2	2018
On infusion of high-dose ascorbate in treating cancer: Is it time for N-acetylcysteine pretreatment to enhance susceptibility and to lower side effects? Medical hypotheses, 2019, Volume: 122 Topics: Acetylcysteine; Administration, Intravenous; Antioxidants; Ascorbic Acid; Copper; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hyaluronic Acid; Immune System; Kidney; Neoplasms; Pancreatic Neoplasms; Sulfhydryl Compounds	2019
Regulation of HMGB1 release protects chemoradiotherapy-associated mucositis. Mucosal immunology, 2019, Volume: 12, Issue:5 Topics: Acetylcysteine; Animals; Chemoradiotherapy; Disease Models, Animal; Female; Histones; HMGB1 Protein; Humans; Mice; Mouth Mucosa; Mucositis; Neoplasms; NF-kappa B; Organic Chemicals; Protective Agents; Protein Transport; Reactive Oxygen Species; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2019
γ-Glutamyltransferase enzyme activity of cancer cells modulates L-γ-glutamyl-p-nitroanilide (GPNA) cytotoxicity. Scientific reports, 2019, 01-29, Volume: 9, Issue:1 Topics: Acetylcysteine; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Enzyme Activation; gamma-Glutamyltransferase; Glutamine; Humans; Hydrolysis; Metabolic Detoxication, Phase I; Neoplasms; Reactive Oxygen Species	2019
Development of near-infrared region luminescent N-acetyl-L-cysteine-coated Ag Nanomedicine (London, England), 2019, Volume: 14, Issue:8 Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Biological Transport; Cell Line, Tumor; Cell Survival; DNA Damage; Free Radical Scavengers; Humans; Infrared Rays; Luminescence; Luminescent Agents; Neoplasms; Oxidative Stress; Particle Size; Quantum Dots; Reactive Oxygen Species; Silver Compounds; Surface Properties	2019
Studies of Jatrogossone A as a Reactive Oxygen Species Inducer in Cancer Cellular Models. Journal of natural products, 2019, 05-24, Volume: 82, Issue:5 Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Jatropha; Membrane Potential, Mitochondrial; Mitophagy; Neoplasms; Poly (ADP-Ribose) Polymerase-1; Reactive Oxygen Species	2019
Therapeutic potential of a pyridoxal-based vanadium(IV) complex showing selective cytotoxicity for cancer versus healthy cells. Journal of cellular physiology, 2013, Volume: 228, Issue:11 Topics: Acetylcysteine; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Membrane Potential, Mitochondrial; Neoplasms; Pyridoxal; Reactive Oxygen Species; Tumor Stem Cell Assay; Vanadium	2013
N-acetylcysteine rescue protocol for nephrotoxicity in children caused by ifosfamide. Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2013, Volume: 20, Issue:2 Topics: Acetylcysteine; Animals; Antidotes; Antineoplastic Agents, Alkylating; Antioxidants; Child; Drug Administration Schedule; Humans; Ifosfamide; Kidney Diseases; Neoplasms; Quality of Life	2013
Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. Journal of immunology (Baltimore, Md. : 1950), 2014, Mar-15, Volume: 192, Issue:6 Topics: Acetylcysteine; Animals; Antigen Presentation; Cell Line, Tumor; Cells, Cultured; Cross-Priming; Culture Media, Conditioned; Cysteine Proteinase Inhibitors; Dendritic Cells; Flow Cytometry; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Interferon-gamma; Lipids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Neoplasms; Ovalbumin; Oxidation-Reduction; Peptide Fragments	2014
The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. The Journal of biological chemistry, 2014, Nov-28, Volume: 289, Issue:48 Topics: Acetylcysteine; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Survival; Copper; Deferoxamine; Female; Free Radical Scavengers; Humans; Iron; Lysosomes; Microtubule-Associated Proteins; Neoplasm Proteins; Neoplasms; Oxidation-Reduction; Phagosomes; Siderophores; Thiosemicarbazones	2014
[Preparation and characterization of tumor targeted CdTe quantum dots modified with functional polymer]. Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:10 Topics: Acetylcysteine; Cadmium Compounds; Humans; Neoplasms; Polymers; Quantum Dots; Spectrophotometry, Ultraviolet; Tellurium	2014
Daucosterol inhibits cancer cell proliferation by inducing autophagy through reactive oxygen species-dependent manner. Life sciences, 2015, Sep-15, Volume: 137 Topics: Acetylcysteine; Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glutathione; Humans; Mice; Neoplasms; Reactive Oxygen Species; Sitosterols; Tumor Stem Cell Assay	2015
Protein disulphide isomerase as a target for nanoparticle-mediated sensitisation of cancer cells to radiation. Nanotechnology, 2016, May-27, Volume: 27, Issue:21 Topics: Acetylcysteine; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Gold; Humans; Membrane Potential, Mitochondrial; Metal Nanoparticles; Mitochondria; Neoplasms; Oxidative Stress; Protein Disulfide-Isomerases; Radiation-Sensitizing Agents	2016
N-acetylcysteine negatively regulates Notch3 and its malignant signaling. Oncotarget, 2016, May-24, Volume: 7, Issue:21 Topics: Acetylcysteine; Amyloid Precursor Protein Secretases; Basic Helix-Loop-Helix Transcription Factors; Catalase; Cell Cycle Proteins; Down-Regulation; Gene Knockdown Techniques; Glutathione; HeLa Cells; Humans; Lysosomes; MCF-7 Cells; Neoplasms; Proteasome Endopeptidase Complex; Protein Domains; Reactive Oxygen Species; Receptor, Notch1; Receptor, Notch3; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase; Transcription Factor HES-1	2016
Perturbation of the Warburg effect increases the sensitivity of cancer cells to TRAIL-induced cell death. Experimental cell research, 2016, 09-10, Volume: 347, Issue:1 Topics: Acetylcysteine; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cysteine-Rich Protein 61; Gene Knockdown Techniques; Gene Silencing; Glycolysis; Heterogeneous-Nuclear Ribonucleoproteins; Humans; Neoplasms; Polypyrimidine Tract-Binding Protein; Protein Multimerization; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation	2016
New bipyridine gold(III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 status. Oncotarget, 2017, Jan-03, Volume: 8, Issue:1 Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; CRISPR-Cas Systems; Drug Resistance, Neoplasm; Free Radical Scavengers; Gene Knockdown Techniques; Humans; Membrane Potential, Mitochondrial; Mitochondria; Neoplasms; Organogold Compounds; Pyridines; Reactive Oxygen Species; Thiocarbamates; Tumor Suppressor Protein p53	2017
The protozoan toxin climacostol inhibits growth and induces apoptosis of human tumor cell lines. Chemico-biological interactions, 2008, Nov-25, Volume: 176, Issue:2-3 Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspase 8; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Membrane Potential, Mitochondrial; Neoplasms; Phosphatidylserines; Reactive Oxygen Species; Resorcinols; Time Factors; Tumor Cells, Cultured	2008
Preferential glutathione conjugation of a reverse diol epoxide compared to a bay region diol epoxide of phenanthrene in human hepatocytes: relevance to molecular epidemiology studies of glutathione-s-transferase polymorphisms and cancer. Chemical research in toxicology, 2009, Mar-16, Volume: 22, Issue:3 Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Bay-Region, Polycyclic Aromatic Hydrocarbon; Female; Glutathione; Glutathione Transferase; Hepatocytes; Humans; Male; Metabolic Detoxication, Phase II; Middle Aged; Neoplasms; Phenanthrenes; Polymorphism, Genetic	2009
Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. Molecular carcinogenesis, 2009, Volume: 48, Issue:12 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Flavonoids; Humans; NAD(P)H Dehydrogenase (Quinone); Neoplasms; Proto-Oncogene Proteins c-mdm2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Scutellaria baicalensis; Tumor Suppressor Protein p53; Umbilical Veins	2009
Comparative analysis of cell death induction by Taurolidine in different malignant human cancer cell lines. Journal of experimental & clinical cancer research : CR, 2010, Mar-07, Volume: 29 Topics: Acetylcysteine; Antineoplastic Agents; Caspases; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glutathione; Humans; Neoplasms; Reactive Oxygen Species; Taurine; Thiadiazines	2010
N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death. Cancer letters, 2010, Dec-08, Volume: 298, Issue:2 Topics: Acetylcysteine; Apoptosis; Blotting, Western; Caspase 3; Cell Line; Cell Line, Tumor; Cell Survival; Copper; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; Microscopy, Confocal; Neoplasms; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species	2010
[N-acetylcysteine-induced reduction in susceptibility of transformed and embryonic cells to lytic activity of natural killer cells]. Tsitologiia, 2010, Volume: 52, Issue:7 Topics: 3T3 Cells; Acetylcysteine; Actins; Animals; Cell Line, Transformed; Cell Line, Tumor; Cytotoxicity, Immunologic; Embryo, Mammalian; Fibroblasts; Humans; Killer Cells, Natural; Male; Mice; Neoplasms; Stress Fibers	2010
A novel 7-azaisoindigo derivative-induced cancer cell apoptosis and mitochondrial dysfunction mediated by oxidative stress. Journal of applied toxicology : JAT, 2011, Volume: 31, Issue:2 Topics: Acetylcysteine; Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Activation; Free Radical Scavengers; Humans; Indoles; Membrane Potential, Mitochondrial; Mitochondria; Neoplasms; Osmolar Concentration; Oxidative Stress; Reactive Oxygen Species; Time Factors	2011
Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M). Chemical research in toxicology, 2011, Apr-18, Volume: 24, Issue:4 Topics: Acetylcysteine; Antineoplastic Agents; Carbon Isotopes; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Microsomes, Liver; NADP; Neoplasms; Spectrometry, Mass, Electrospray Ionization; Sulfonamides	2011
Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione. Biochimie, 2011, Volume: 93, Issue:7 Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Acetylcysteine; Animals; Anti-Inflammatory Agents; Buthionine Sulfoximine; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Free Radical Scavengers; Glutathione; Glycyrrhetinic Acid; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Neoplasms; Oxidation-Reduction; Protein Binding; Protein Conformation; Reactive Oxygen Species; Up-Regulation	2011
ROS implication in a new antitumor strategy based on non-thermal plasma. International journal of cancer, 2012, May-01, Volume: 130, Issue:9 Topics: Acetylcysteine; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; DNA Damage; Female; HCT116 Cells; Humans; Mice; Mice, Nude; Neoplasms; Plasma Gases; Radiation, Ionizing; Reactive Oxygen Species; Transplantation, Heterologous	2012
Stereospecific total syntheses of proteasome inhibitors omuralide and lactacystin. The Journal of organic chemistry, 2011, Oct-21, Volume: 76, Issue:20 Topics: Acetylcysteine; Apoptosis; Chemistry, Pharmaceutical; Crystallography, X-Ray; Cysteine Proteinase Inhibitors; Humans; Lactones; Magnetic Resonance Spectroscopy; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Stereoisomerism	2011
Synthesis of NAC capped near infrared-emitting CdTeS alloyed quantum dots and application for in vivo early tumor imaging. Dalton transactions (Cambridge, England : 2003), 2012, Apr-28, Volume: 41, Issue:16 Topics: Acetylcysteine; Animals; Cadmium Compounds; Cell Line, Tumor; Cell Survival; Diagnostic Imaging; Female; Human Umbilical Vein Endothelial Cells; Humans; Kidney; Liver; Lung; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Transplantation; Neoplasms; Quantum Dots; Sulfides; Tellurium	2012
Role of mitochondrial uncoupling protein 2 in cancer cell resistance to gemcitabine. Biochimica et biophysica acta, 2012, Volume: 1823, Issue:10 Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Iridoids; Mitochondrial Proteins; Neoplasms; Poly(ADP-ribose) Polymerases; RNA, Messenger; Superoxide Dismutase; Superoxides; Uncoupling Agents; Uncoupling Protein 2	2012
In vitro evaluation of silver nanoparticles on human tumoral and normal cells. Toxicology mechanisms and methods, 2013, Volume: 23, Issue:3 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Biomarkers; Cell Membrane; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Fibroblasts; Hep G2 Cells; HL-60 Cells; Humans; L-Lactate Dehydrogenase; Metal Nanoparticles; Mitochondria; Neoplasms; Oxidative Stress; Silver Compounds; Time Factors	2013
GADD153-mediated anticancer effects of N-(4-hydroxyphenyl)retinamide on human hepatoma cells. The Journal of biological chemistry, 2002, Oct-11, Volume: 277, Issue:41 Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Cycle; DNA Fragmentation; Fenretinide; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation; Genes, Reporter; Humans; Neoplasms; NF-kappa B; Sesquiterpenes; Transcription Factor CHOP; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured	2002
Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase. Experimental cell research, 2003, Oct-15, Volume: 290, Issue:1 Topics: Acetylcysteine; Animals; Arsenites; Carcinogens; Catalase; Cell Line; Cell Transformation, Neoplastic; Enzyme Inhibitors; Hydrogen Peroxide; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Reactive Oxygen Species; Ribosomal Protein S6 Kinases, 70-kDa; Transcription Factor AP-1	2003
Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells. The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5 Topics: Acetylcysteine; Adherens Junctions; Animals; Blotting, Northern; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Claudin-1; Claudin-3; Claudin-4; Claudins; Cycloheximide; Detergents; Dogs; Epithelium; ErbB Receptors; Gene Expression Regulation; Hepatocyte Growth Factor; Immunoblotting; Kidney; Membrane Proteins; Microscopy, Fluorescence; Neoplasms; Octoxynol; Phenotype; Protein Synthesis Inhibitors; Signal Transduction; Tight Junctions; Time Factors	2004
Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest. Carcinogenesis, 2004, Volume: 25, Issue:8 Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Separation; Coloring Agents; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Flow Cytometry; G1 Phase; Humans; Isothiocyanates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitosis; Neoplasm Transplantation; Neoplasms; Phosphorylation; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; S Phase; Time Factors; Tumor Suppressor Proteins; Up-Regulation; Vegetables	2004
Inhibition of tumor growth by replacing glutathione with N-acetyl-L-cysteine. Medical hypotheses, 2004, Volume: 63, Issue:1 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Cell Proliferation; Glycolysis; Humans; Neoplasms; Signal Transduction	2004
Tumor profile of novel p53 heterozygous Tg.AC (v-Ha-ras) bitransgenic mice treated with benzo(a)pyrene and fed dietary N-acetyl-L-cysteine (NAC). Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:2 Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Carcinogens; Diet; Female; Gastric Mucosa; Genes, p53; Genes, ras; Hematologic Neoplasms; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Neoplasms; Papilloma; Pseudolymphoma; Sex Characteristics; Survival Analysis; Urinary Bladder Neoplasms	2004
Dysregulation of apoptosis by benzene metabolites and their relationships with carcinogenesis. Biochimica et biophysica acta, 2004, Sep-06, Volume: 1690, Issue:1 Topics: Acetylcysteine; Animals; Apoptosis; Benzene; Benzoquinones; Caspase 3; Caspases; Cell Division; Enzyme Activation; Guanosine; Hydroquinones; Mice; Neoplasms; NIH 3T3 Cells; Reactive Oxygen Species	2004
Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity. Molecular cancer therapeutics, 2004, Volume: 3, Issue:9 Topics: Acetylcysteine; Adenoviridae; Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Combined Modality Therapy; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Neoplasm; Early Growth Response Protein 1; Genetic Therapy; Genetic Vectors; Humans; Immediate-Early Proteins; Male; Neoplasms; Neovascularization, Pathologic; Promoter Regions, Genetic; Prostatic Neoplasms; Rats; Transcription Factors; Tumor Necrosis Factor-alpha; Up-Regulation; Xenograft Model Antitumor Assays	2004
On metronomic chemotherapy: modulation of angiogenesis mediated by VEGE-A. Acta oncologica (Stockholm, Sweden), 2006, Volume: 45, Issue:2 Topics: Acetylcysteine; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Endothelial Cells; Male; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stem Cells; Vascular Endothelial Growth Factor A; Weight Gain	2006
Influence of FHIT on benzo[a]pyrene-induced tumors and alopecia in mice: chemoprevention by budesonide and N-acetylcysteine. Proceedings of the National Academy of Sciences of the United States of America, 2006, May-16, Volume: 103, Issue:20 Topics: Acetylcysteine; Acid Anhydride Hydrolases; Alopecia Areata; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Female; Genes, Tumor Suppressor; Lung; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neoplasms; Stomach	2006
Reduced nonprotein thiols inhibit activation and function of MMP-9: implications for chemoprevention. Free radical biology & medicine, 2006, Oct-15, Volume: 41, Issue:8 Topics: Acetylcysteine; Anticarcinogenic Agents; Catalytic Domain; Cell Line, Tumor; Chemoprevention; Enzyme Activation; Glutathione; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Models, Molecular; Neoplasms; Oxidation-Reduction; Phenylmercuric Acetate; Protein Conformation; Zinc	2006
Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:4 Topics: Acetylcysteine; Animals; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA-Binding Proteins; Free Radical Scavengers; Mice; Mice, Knockout; Neoplasms; Protein Serine-Threonine Kinases; Psychomotor Performance; Tumor Suppressor Proteins	2008
Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells. Cancer science, 2008, Volume: 99, Issue:5 Topics: Acetylcysteine; Boronic Acids; Caffeine; Cells, Cultured; Cisplatin; Cysteine Proteinase Inhibitors; DNA Damage; DNA Repair; DNA Replication; HeLa Cells; Humans; Leupeptins; Neoplasms; Proteasome Inhibitors; Tumor Cells, Cultured; Ultraviolet Rays	2008
Anti-oxidant treatment enhances anti-tumor cytotoxicity of (-)-gossypol. Cancer biology & therapy, 2008, Volume: 7, Issue:5 Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Cell Line; Cell Line, Tumor; Cell Survival; Drug Synergism; Gene Expression Regulation, Neoplastic; Gossypol; Humans; Models, Biological; Neoplasms; Oligonucleotide Array Sequence Analysis; Oxidants; Reactive Oxygen Species	2008
Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms. Carcinogenesis, 2008, Volume: 29, Issue:5 Topics: Acetylcysteine; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Glutathione Transferase; Humans; Inactivation, Metabolic; Models, Molecular; Neoplasms; Phenanthrenes; Polymorphism, Genetic; Spectrometry, Mass, Electrospray Ionization	2008
N-Acetylcysteine (NAC): a significant chemoprotective adjunct. Introduction. Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1 Topics: Acetylcysteine; Antineoplastic Agents; Drug Therapy, Combination; Humans; Neoplasms	1983
N-acetylcysteine (NAC): a significant chemoprotective adjunct. Proceedings of a symposium, September 8 and 10, 1982. Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1 Topics: Acetylcysteine; Drug Therapy, Combination; Humans; Neoplasms	1983
Prophylaxis of ifosfamide toxicity with oral acetylcysteine. Seminars in oncology, 1983, Volume: 10, Issue:1 Suppl 1 Topics: Acetylcysteine; Adenocarcinoma; Aged; Carcinoma, Squamous Cell; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hematuria; Humans; Ifosfamide; Kidney Diseases; Male; Middle Aged; Nausea; Neoplasms; Vomiting	1983
Clinical development plan: N-Acetyl-l-cysteine. Journal of cellular biochemistry. Supplement, 1994, Volume: 20 Topics: Acetylcysteine; Animals; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cricetinae; Drug Approval; Drug Evaluation, Preclinical; Humans; Mice; Neoplasms; Rats	1994
Pulmonary alveolar macrophages in molecular epidemiology and chemoprevention of cancer. Environmental health perspectives, 1993, Volume: 99 Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Acetylcysteine; Adolescent; Adult; Aged; Animals; Benzo(a)pyrene; DNA; DNA Adducts; Female; Humans; Macrophages, Alveolar; Male; Micronuclei, Chromosome-Defective; Middle Aged; Neoplasms; Rats; Rats, Sprague-Dawley; Smoking	1993
The human multidrug resistance P-glycoprotein is inactive when its maturation is inhibited: potential for a role in cancer chemotherapy. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:13 Topics: Acetylcysteine; Acquired Immunodeficiency Syndrome; Adenosine Triphosphatases; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Membrane; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Resistance, Multiple; Glycosylation; Humans; Leupeptins; Multienzyme Complexes; Neoplasms; Proteasome Endopeptidase Complex; Protein Conformation; Protein Folding; Protein Precursors; Protein Processing, Post-Translational	1999
Restoration of functional defects in peripheral blood mononuclear cells isolated from cancer patients by thiol antioxidants alpha-lipoic acid and N-acetyl cysteine. International journal of cancer, 2000, Jun-15, Volume: 86, Issue:6 Topics: Acetylcysteine; Adult; Aged; Antioxidants; Cell Cycle; Cytokines; fas Receptor; Flow Cytometry; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Middle Aged; Neoplasms; Nitric Oxide; Receptors, Interleukin-2; Thioctic Acid	2000
Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. Leukemia, 2000, Volume: 14, Issue:7 Topics: Acetylcysteine; Acrylates; Amino Acid Chloromethyl Ketones; Apoptosis; Boronic Acids; Bortezomib; Calpain; Cathepsins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Drug Synergism; Genes, p53; Humans; Jurkat Cells; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells	2000
N-acetylcysteine. Alternative medicine review : a journal of clinical therapeutic, 2000, Volume: 5, Issue:5 Topics: Acetaminophen; Acetylcysteine; Antidotes; Expectorants; Heart Diseases; Humans; Neoplasms; Respiratory Tract Diseases	2000
Proteasome inhibitors differentially affect heat shock protein response in cancer cells. International journal of molecular medicine, 2001, Volume: 8, Issue:4 Topics: Acetylcysteine; Antigens, Neoplasm; Blotting, Western; Cell Division; Cell Line; Cell Survival; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Heat-Shock Proteins; HL-60 Cells; Humans; K562 Cells; Leupeptins; Multienzyme Complexes; Neoplasms; Proteasome Endopeptidase Complex; Tumor Cells, Cultured	2001
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine. Cancer research, 2002, Mar-01, Volume: 62, Issue:5 Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, myc; Humans; Neoplasms; Penicillamine; Tumor Suppressor Protein p53	2002
N-acetylcysteine as chemoprotectant in cancer chemotherapy. Lancet (London, England), 1991, Jul-27, Volume: 338, Issue:8761 Topics: Acetylcysteine; Antineoplastic Agents; Humans; Neoplasms	1991
In vitro activity of paldimycin (U-70138F) against gram-positive bacteria isolated from patients with cancer. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:4 Topics: Acetylcysteine; Bacterial Infections; Disaccharides; Glycopeptides; Gram-Positive Bacteria; Neoplasms; Vancomycin	1987