acetylcysteine and B-Cell Chronic Lymphocytic Leukemia

acetylcysteine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's10 (83.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balakrishnan, K; Gandhi, V; Keating, MJ; Wierda, WG1
Carson, DA; Endo, T; Kipps, TJ; Liu, JX; Lu, D; Schmidt-Wolf, IG; Willert, K; Yao, S; Zhou, H1
Bogner, C; Decker, T; Hipp, S; Peschel, C; Ringshausen, I; Schneller, F1
Adjei, AA; Bone, N; Bruzek, LM; Chandra, J; Hackbarth, J; Karp, JE; Kaufmann, SH; Kay, NE; Le, S; Loegering, D; Narayanan, VL; Sausville, EA; Tefferi, A1
Byrd, JC; Cheney, CM; Green, JM; Huang, P; Jefferson, S; Johnson, AJ; Lin, TS; Mone, AP; Pelicano, H; Tso, JY1
Binet, JL; Cosset, JM; Delic, J; Dumont, J; Magdelénat, H; Masdehors, P; Omura, S1
Cosset, JM; Delic, J; Dumont, J; Magdelénat, H; Masdehors, P; Mentz, F; Merle-Béral, H; Omura, S1
Delic, J; Magdelénat, H; Maloum, K; Masdehors, P; Merle-Béral, H; Omura, S1
Delic, J; Magdelénat, H; Masdehors, P; Merle-Béral, H1
Acquaah-Mensah, GK; Biswal, SS; Datta, K; Kehrer, JP1
Almond, JB; Cain, K; Cohen, GM; Dinsdale, D; Hunter, A; Snowden, RT1
Cawley, JC; Kamiguti, AS; Moran, EC; Pettitt, AR1

Reviews

1 review(s) available for acetylcysteine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation.
    Leukemia & lymphoma, 2000, Volume: 38, Issue:5-6

    Topics: Acetylcysteine; Apoptosis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Multienzyme Complexes; Proteasome Endopeptidase Complex; Signal Transduction; Ubiquitins

2000

Other Studies

11 other study(ies) available for acetylcysteine and B-Cell Chronic Lymphocytic Leukemia

ArticleYear
Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells.
    Blood, 2008, Sep-01, Volume: 112, Issue:5

    Topics: Acetylcysteine; Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Antioxidants; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Biological Transport, Active; Calpain; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Dipeptides; Gossypol; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Mitochondrial Membranes; Molecular Mimicry; Reactive Oxygen Species; Superoxides

2008
Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway.
    PloS one, 2009, Dec-14, Volume: 4, Issue:12

    Topics: Acetylcysteine; beta Catenin; Cell Line, Tumor; Cell Survival; Cyclin D1; Drug Screening Assays, Antitumor; Ethacrynic Acid; Fibronectins; Frizzled Receptors; Gene Expression Regulation, Leukemic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoid Enhancer-Binding Factor 1; Protein Binding; Receptors, G-Protein-Coupled; Signal Transduction; Wnt Proteins

2009
Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways.
    Experimental hematology, 2003, Volume: 31, Issue:3

    Topics: Acetylcysteine; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Multienzyme Complexes; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Proteins

2003
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.
    Blood, 2003, Dec-15, Volume: 102, Issue:13

    Topics: Acetylcysteine; Adamantane; Antioxidants; Apoptosis; Buthionine Sulfoximine; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Glutathione; Humans; Hydroquinones; K562 Cells; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Quinones; Reactive Oxygen Species; Tumor Stem Cell Assay; Tyrphostins

2003
Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells.
    Blood, 2004, Mar-01, Volume: 103, Issue:5

    Topics: Acetylcysteine; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Chromones; Cytoskeleton; Electron Transport; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Membrane Microdomains; Mitochondria; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Time Factors

2004
The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis.
    British journal of cancer, 1998, Volume: 77, Issue:7

    Topics: Acetylcysteine; Apoptosis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Resistance, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Multienzyme Complexes; Neoplasm Proteins; NF-kappa B; Proteasome Endopeptidase Complex; Radiation Tolerance; Tumor Necrosis Factor-alpha

1998
Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin.
    British journal of haematology, 1999, Volume: 105, Issue:3

    Topics: Acetylcysteine; Aged; Apoptosis; Blotting, Western; Cysteine Proteinase Inhibitors; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1999
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes.
    Blood, 2000, Jul-01, Volume: 96, Issue:1

    Topics: Acetylcysteine; Adenosine Triphosphatases; Apoptosis; bcl-2-Associated X Protein; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; fas Receptor; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Multienzyme Complexes; Neoplasm Proteins; Nuclear Proteins; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Reference Values; Tumor Suppressor Protein p53; Ubiquitins

2000
Changes in ceramide and sphingomyelin following fludarabine treatment of human chronic B-cell leukemia cells.
    Toxicology, 2000, Nov-23, Volume: 154, Issue:1-3

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Carboxylic Acids; Caspase 3; Caspase Inhibitors; Caspases; Ceramides; Chromatography, Thin Layer; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fumonisins; Glutathione; Humans; Image Processing, Computer-Assisted; Leukemia, Lymphocytic, Chronic, B-Cell; Phosphatidylserines; Sphingomyelins; Tumor Cells, Cultured; Vidarabine

2000
Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex.
    Leukemia, 2001, Volume: 15, Issue:9

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Apoptotic Protease-Activating Factor 1; Blotting, Western; Caspase 9; Caspases; Cysteine Endopeptidases; Cytochrome c Group; Cytosol; Enzyme Activation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leupeptins; Microscopy, Electron; Molecular Weight; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Biosynthesis; Proteins; Tumor Cells, Cultured

2001
Cytoprotective antioxidant activity of serum albumin and autocrine catalase in chronic lymphocytic leukaemia.
    British journal of haematology, 2002, Volume: 116, Issue:2

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Autocrine Communication; Catalase; Cell Count; Cryoprotective Agents; Culture Media, Conditioned; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Leukemia, Lymphocytic, Chronic, B-Cell; Mitochondria; Oxidative Stress; Ruthenium Red; Serum Albumin; Tumor Cells, Cultured

2002