acetylcysteine has been researched along with Autoimmune Diabetes in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 6 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, J; Han, Q; Hu, L; Huo, H; Li, X; Li, Y; Liao, J; Ma, F; Pan, J; Tang, Z; Wu, H; Zhang, H | 1 |
| Guo, J; Han, Q; Hu, L; Huo, H; Li, X; Li, Y; Ma, F; Pan, J; Tang, Z; Wu, H; Zhang, H; Zhao, M | 1 |
| Bai, Y; Huang, J; Liao, J; Pang, X; Qiu, W; Su, R; Tang, Z; Wang, R; Xie, W; Xiong, Z; Zhang, X; Zhou, S | 1 |
| Ding, Q; Han, Q; Li, H; Li, T; Liao, J; Sun, B; Tang, Z; Wang, M | 1 |
| He, YL; Li, XM; Nie, F; Xiong, Y; Zhou, XK | 1 |
| Caldeira, EJ; Cunha, MR; Galdeano, EA; Pinto, CAL; Prudente, RCS; Santos, GR | 1 |
| Stokes, KY; Wang, B; Yee Aw, T | 1 |
| Gan, X; Gao, X; Hei, Z; Irwin, MG; Lei, S; Liu, Y; Wang, T; Xia, Z; Xia, ZY; Xu, J | 1 |
| Alicic, RZ; Tuttle, KR | 1 |
| Irwin, MG; Li, H; Li, Y; Lin, J; Wang, M; Wang, T; Xia, Z | 1 |
| Aw, TY; Stokes, KY; Wang, B | 1 |
| Abboud, HE; Gorin, Y; Habib, SL; Simone, S; Velagapudi, C | 1 |
| Darmaun, D; Hartman, BK; Mauras, N; Smith, SD; Sweeten, S; Welch, S | 1 |
| Ha, H; Kim, YO; Lee, HB; Noh, H; Oh, EY; Seo, JY; Yu, MR | 1 |
| Irie, J; Oikawa, Y; Saruta, T; Shigihara, T; Shimada, A | 1 |
| Becker, TC; Cao, W; Collins, QF; Collins, S; Daniel, KW; Floering, L; Lupo, EG; Robidoux, J; Xiong, Y | 1 |
| Coderre, L; Pelletier, A | 1 |
| Bray, TM; Chen, G; Ho, E | 1 |
| Floyd, RA; Graham, KL; Kotake, Y; Tabatabaie, T; Vasquez, AM | 1 |
| Bocchini, JA; Jain, SK; Kannan, K; Lim, G; McVie, R | 1 |
1 review(s) available for acetylcysteine and Autoimmune Diabetes
| Article | Year |
|---|---|
Novel therapies for diabetic kidney disease.
Topics: Acetylcysteine; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Antioxidants; Bosentan; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelins; Enzyme Inhibitors; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Indoles; Janus Kinases; Maleimides; Polyamines; Protein Kinase C; Pyridones; Pyridoxamine; Sevelamer; Sulfonamides | 2014 |
2 trial(s) available for acetylcysteine and Autoimmune Diabetes
| Article | Year |
|---|---|
N-acetylcysteine combined with insulin alleviates the oxidative damage of cerebrum via regulating redox homeostasis in type 1 diabetic mellitus canine.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Catalase; Cerebrum; Claudin-1; Diabetes Mellitus, Type 1; Dogs; Glutathione Disulfide; Homeostasis; Hydrogen Peroxide; Insulin; Lipids; Occludin; Oxidation-Reduction; Oxidative Stress; RNA, Messenger | 2022 |
Poorly controlled type 1 diabetes is associated with altered glutathione homeostasis in adolescents: apparent resistance to N-acetylcysteine supplementation.
Topics: Acetylcysteine; Adolescent; Deuterium; Diabetes Mellitus, Type 1; Female; Glutathione; Glycated Hemoglobin; Homeostasis; Humans; Male | 2008 |
17 other study(ies) available for acetylcysteine and Autoimmune Diabetes
| Article | Year |
|---|---|
N-acetyl-L-cysteine ameliorates hepatocyte pyroptosis of dog type 1 diabetes mellitus via suppression of NLRP3/NF-κB pathway.
Topics: Acetylcysteine; Animals; Diabetes Mellitus, Type 1; Dogs; Hepatocytes; Insulin; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats; Rats, Sprague-Dawley; Streptozocin | 2022 |
N-acetylcysteine combined with insulin attenuates myocardial injury in canines with type 1 diabetes mellitus by modulating TNF-α-mediated apoptotic pathways and affecting linear ubiquitination.
Topics: Acetylcysteine; Animals; Apoptosis; Diabetes Mellitus, Type 1; Dogs; Humans; Insulin; NF-kappa B; Tumor Necrosis Factor-alpha; Ubiquitination | 2023 |
N-acetylcysteine alleviates oxidative stress and apoptosis and prevents skeletal muscle atrophy in type 1 diabetes mellitus through the NRF2/HO-1 pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Diabetes Mellitus, Type 1; Dogs; Insulins; Kelch-Like ECH-Associated Protein 1; Muscle, Skeletal; Muscular Atrophy; NF-E2-Related Factor 2; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2023 |
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats.
Topics: Acetylcysteine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Free Radical Scavengers; Glycosylation; Heart Diseases; Insulin Resistance; Male; Mitochondria; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Papillary Muscles; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2021 |
Effect of antioxidant treatment with n-acetylcysteine and swimming on lipid expression of sebaceous glands in diabetic mice.
Topics: Acetylcysteine; Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Type 1; Female; Humans; Immunohistochemistry; Lipids; Mice, Inbred BALB C; Mice, Inbred NOD; Perilipin-2; Sebaceous Glands; Skin; Swimming | 2021 |
N-acetylcysteine attenuates systemic platelet activation and cerebral vessel thrombosis in diabetes.
Topics: Acetylcysteine; Animals; Blood Platelets; Brain; Diabetes Mellitus, Type 1; Male; Mice, Inbred C57BL; Platelet Activation; Platelet Aggregation Inhibitors; Pyruvaldehyde; Streptozocin; Thrombosis | 2018 |
Antioxidant N-acetylcysteine attenuates the reduction of Brg1 protein expression in the myocardium of type 1 diabetic rats.
Topics: Acetylcysteine; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dinoprost; DNA Helicases; Free Radical Scavengers; Heart; Heme Oxygenase-1; Interleukin-6; Isoprostanes; Myocardium; Nuclear Proteins; Phosphorylation; Rats; STAT3 Transcription Factor; Transcription Factors; Tumor Necrosis Factor-alpha | 2013 |
N-Acetylcysteine Restores Sevoflurane Postconditioning Cardioprotection against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats.
Topics: Acetylcysteine; Adiponectin; Animals; Antioxidants; CD36 Antigens; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Transcription Factors; Male; Methyl Ethers; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nerve Tissue Proteins; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; Sevoflurane; STAT3 Transcription Factor; Time Factors; Troponin I | 2016 |
The protection conferred against ischemia-reperfusion injury in the diabetic brain by N-acetylcysteine is associated with decreased dicarbonyl stress.
Topics: Acetylcysteine; Animals; Antioxidants; Blood-Brain Barrier; Brain; Cerebral Infarction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose; Glutamate-Cysteine Ligase; Glutathione; Humans; Mice; Oxidative Stress; Pyruvaldehyde; Reperfusion Injury; Stroke | 2016 |
Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Cells, Cultured; Deoxyguanosine; Diabetes Mellitus; Diabetes Mellitus, Type 1; DNA Damage; DNA Glycosylases; Glucose; Hydrogen Peroxide; Immunoblotting; Immunohistochemistry; Kidney; Mice; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Rats; Reactive Oxygen Species; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2008 |
Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury.
Topics: Acetylcysteine; Amides; Animals; Antioxidants; Biphenyl Compounds; Cell Line; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Kidney; Male; Mice; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Recombinant Proteins; Repressor Proteins; RNA Interference; RNA, Messenger; Transforming Growth Factor beta1; Valproic Acid | 2009 |
N-acetyl-cysteine accelerates transfer of diabetes into non-obese diabetic scid mice.
Topics: Acetylcysteine; Animals; Cytokines; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Islets of Langerhans; Lymphocyte Transfusion; Mice; Mice, Inbred NOD; Mice, SCID; Polymerase Chain Reaction; Spleen; Time Factors | 2004 |
p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis.
Topics: Acetylcysteine; Adenoviridae; Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Silencing; Glucagon; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Hepatocytes; Imidazoles; Liver; Mice; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Promoter Regions, Genetic; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Streptozocin; Trans-Activators; Transcription Factors; Transfection | 2005 |
Ketone bodies alter dinitrophenol-induced glucose uptake through AMPK inhibition and oxidative stress generation in adult cardiomyocytes.
Topics: 2,4-Dinitrophenol; 3-Hydroxybutyric Acid; Acetyl-CoA Carboxylase; Acetylcysteine; AMP-Activated Protein Kinases; Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Free Radical Scavengers; Glucose; Ketone Bodies; Male; Multienzyme Complexes; Myocytes, Cardiac; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Uncoupling Agents | 2007 |
Supplementation of N-acetylcysteine inhibits NFkappaB activation and protects against alloxan-induced diabetes in CD-1 mice.
Topics: Acetylcysteine; Administration, Oral; Alloxan; Animals; Blood Glucose; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Male; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pancreas | 1999 |
Inhibition of the cytokine-mediated inducible nitric oxide synthase expression in rat insulinoma cells by phenyl N-tert-butylnitrone.
Topics: Acetylcysteine; Animals; Blotting, Northern; Cell Survival; Cyclic N-Oxides; Cytokines; Diabetes Mellitus, Type 1; Enzyme Induction; Enzyme Inhibitors; Free Radical Scavengers; Immunoblotting; Insulinoma; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Nitrogen Oxides; Protective Agents; Rats; RNA, Messenger; Thioctic Acid; Tumor Cells, Cultured | 2000 |
Hyperketonemia increases tumor necrosis factor-alpha secretion in cultured U937 monocytes and Type 1 diabetic patients and is apparently mediated by oxidative stress and cAMP deficiency.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetylcysteine; Antioxidants; Cyclic AMP; Diabetes Mellitus, Type 1; Humans; Ketone Bodies; Mitogen-Activated Protein Kinases; Monocytes; Oxidative Stress; Protein Kinase C; Reference Values; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2002 |