acetylcysteine and Autism

acetylcysteine has been researched along with Autism in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (69.23)24.3611
2020's4 (30.77)2.80

Authors

AuthorsStudies
Bishayee, K; Huh, SO; Kang, J1
Deng, YN; He, XL; Li, YF; Wang, LJ; Wang, T; Zhang, YH1
Bristow, GC; Dawson, N; Mitchell, EJ; Morris, BJ; Openshaw, RL; Pratt, JA; Thomson, DM1
Cheng, YS; Hung, KC; Sun, CK1
Cui, W; Wen, X; Zhai, Q; Zhang, T; Zhang, Y1
Aldbass, AM; Bhat, RS; El-Ansary, A1
Frye, RE; James, SJ; Melnyk, S; Rose, S; Slattery, J; Tippett, M; Wynne, R1
Marler, S; Sanders, KB; Veenstra-VanderWeele, J1
Bent, S; Hendren, RL1
Racz, R; Sohoni, P; Sweet, BV1
Berk, M; Dean, OM; Dodd, S; Gray, KM; Mohebbi, M; Tonge, BJ; Vick, T; Villagonzalo, KA1
Frazier, TW; Fung, LK; Hardan, AY; Herzenberg, LA; Libove, RA; Nair, S; Obukhanych, TV; Tirouvanziam, R1
Berk, M; Bush, AI; Dean, OM1

Reviews

2 review(s) available for acetylcysteine and Autism

ArticleYear
Complementary and alternative treatments for autism part 1: evidence-supported treatments.
    AMA journal of ethics, 2015, Apr-01, Volume: 17, Issue:4

    Topics: Acetylcysteine; Animals; Antipsychotic Agents; Aripiprazole; Autistic Disorder; Complementary Therapies; Disease Models, Animal; Evidence-Based Medicine; Free Radical Scavengers; Gastrointestinal Tract; Humans; Inflammation; Mice; Oxidative Stress; Randomized Controlled Trials as Topic; Risperidone; United States; United States Food and Drug Administration; Vitamin B 12

2015
Oral acetylcysteine for neuropsychiatric disorders.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Jun-01, Volume: 72, Issue:11

    Topics: Acetylcysteine; Administration, Oral; Autistic Disorder; Bipolar Disorder; Complementary Therapies; Dietary Supplements; Humans; Mental Disorders; Obsessive-Compulsive Disorder; Schizophrenia; Trichotillomania

2015

Trials

2 trial(s) available for acetylcysteine and Autism

ArticleYear
A randomised, double blind, placebo-controlled trial of a fixed dose of N-acetyl cysteine in children with autistic disorder.
    The Australian and New Zealand journal of psychiatry, 2017, Volume: 51, Issue:3

    Topics: Acetylcysteine; Autistic Disorder; Child; Child, Preschool; Double-Blind Method; Female; Free Radical Scavengers; Humans; Male; Treatment Failure

2017
A randomized controlled pilot trial of oral N-acetylcysteine in children with autism.
    Biological psychiatry, 2012, Jun-01, Volume: 71, Issue:11

    Topics: Acetylcysteine; Autistic Disorder; Child; Child, Preschool; Double-Blind Method; Female; Free Radical Scavengers; Humans; Irritable Mood; Male; Pilot Projects; Stereotyped Behavior; Treatment Outcome

2012

Other Studies

9 other study(ies) available for acetylcysteine and Autism

ArticleYear
Azoxystrobin Impairs Neuronal Migration and Induces ROS Dependent Apoptosis in Cortical Neurons.
    International journal of molecular sciences, 2021, Nov-19, Volume: 22, Issue:22

    Topics: Acetylcysteine; Animals; Apoptosis; Autistic Disorder; Cell Movement; Cell Survival; Female; Fungicides, Industrial; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Mitochondria; Neurogenesis; Neuronal Outgrowth; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Pyrimidines; Reactive Oxygen Species; Strobilurins

2021
N-acetylcysteine improves autism-like behavior by recovering autophagic deficiency and decreasing Notch-1/Hes-1 pathway activity.
    Experimental biology and medicine (Maywood, N.J.), 2023, Volume: 248, Issue:11

    Topics: Acetylcysteine; Animals; Autistic Disorder; Behavior, Animal; Disease Models, Animal; Female; Humans; Neuroblastoma; Prenatal Exposure Delayed Effects; Rats; Valproic Acid

2023
Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions.
    Scientific reports, 2020, 07-23, Volume: 10, Issue:1

    Topics: Acetylcysteine; Animals; Anxiety; Autistic Disorder; Chromosome Deletion; Chromosomes, Mammalian; Disease Models, Animal; Gene-Environment Interaction; Humans; Male; Mice, Inbred C57BL; Motor Activity; Phenotype; Social Behavior; Social Interaction

2020
N-acetylcysteine is effective as add-on therapy to risperidone-based combination for children with autistic disorders.
    The Australian and New Zealand journal of psychiatry, 2022, Volume: 56, Issue:1

    Topics: Acetylcysteine; Antipsychotic Agents; Autistic Disorder; Child; Humans; Irritable Mood; Risperidone

2022
N-acetylcysteine ameliorates repetitive/stereotypic behavior due to its antioxidant properties without activation of the canonical Wnt pathway in a valproic acid-induced rat model of autism.
    Molecular medicine reports, 2017, Volume: 16, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Autistic Disorder; Behavior, Animal; beta Catenin; Brain; Glutathione; Glycogen Synthase Kinase 3 beta; Male; Malondialdehyde; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Valproic Acid; Wnt Signaling Pathway

2017
Protective and therapeutic potency of N-acetyl-cysteine on propionic acid-induced biochemical autistic features in rats.
    Journal of neuroinflammation, 2013, Mar-27, Volume: 10

    Topics: Acetylcysteine; Analysis of Variance; Animals; Autistic Disorder; Brain; Comet Assay; Disease Models, Animal; DNA; Gene Expression Regulation; Glutathione Transferase; Interferon-gamma; Male; Neuroprotective Agents; Propionates; Rats; ROC Curve; Serotonin

2013
Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines.
    Translational psychiatry, 2014, Apr-01, Volume: 4

    Topics: Acetylcysteine; Autistic Disorder; Cell Line; Child; Glutathione; Humans; Lymphocytes; Male; Mitochondria; Oxidative Stress; Reactive Oxygen Species

2014
N-acetylcysteine as treatment for self-injurious behavior in a child with autism.
    Journal of child and adolescent psychopharmacology, 2014, Volume: 24, Issue:4

    Topics: Acetylcysteine; Autistic Disorder; Child, Preschool; Humans; Male; Self-Injurious Behavior

2014
Translating the Rosetta Stone of N-acetylcysteine.
    Biological psychiatry, 2012, Jun-01, Volume: 71, Issue:11

    Topics: Acetylcysteine; Autistic Disorder; Behavior; Event-Related Potentials, P300; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Humans; Ketamine; Male

2012