acetylcysteine and Atherosclerosis

acetylcysteine has been researched along with Atherosclerosis in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (32.26)29.6817
2010's15 (48.39)24.3611
2020's6 (19.35)2.80

Authors

AuthorsStudies
Doulamis, IP; Iliopoulos, DC; Kaminiotis, VV; Kapelouzou, A; Kontogiannis, C; Mastrogeorgiou, M; Mylonas, KS; Nikiteas, N; Siasos, G; Spartalis, E; Spartalis, M; Toutouzas, K1
Bu, H; Chen, Y; Cui, L; Cui, Y; Gong, X; Hu, K; Jiang, Y; Liu, Q; Ma, X; Si, Z; Sun, H; Xu, Y; Zhu, Q; Zhuo, X1
Cui, Y; Flaker, GC; Hao, H; Jiang, M; Liu, Q; Liu, X; Liu, Z; Xiao, Y; Zhou, S; Zhu, Q1
Chen, SY; Cui, Y; Hao, H; Hill, MA; Li, DP; Liu, X; Liu, Z; Martinez-Lemus, LA; Wang, M; Wu, H; Xia, X; Xu, C; Zhang, L; Zhu, Q1
Kuo, CC; Lee, GL; Lin, P; Wen, HT; Wu, JY; Yeh, CC1
Fang, X; Liu, L; Wang, B; Zhou, S; Zhu, M1
Bakoyiannis, C; Iliopoulos, D; Kapelouzou, A; Liakakos, T; Mastrogeorgiou, M; Mylonas, KS; Nikiteas, N; Schizas, D; Spartalis, E; Spartalis, M1
Müller, GA; Patschan, D1
Accili, D; Ferrante, AW; Murphy, AJ; Subramanian, V; Tall, AR; Tsuchiya, K; Westerterp, M1
Damdindorj, L; Hosokawa, Y; Hossain, E; Karnan, S; Konishi, H; Konishi, Y; Ota, A; Takahashi, M1
Chen, CS; Cho, HJ; Hseu, YC; Lin, CW; Lin, SW; Lu, FJ; Senthil Kumar, KJ; Shen, PC; Yang, HL1
Eggermont, K; Feng, Y; Gao, M; Liu, G; Schouteden, S; Sorci-Thomas, MG; Van Veldhoven, PP; Verfaillie, CM; Zhao, D1
Cui, L; Cui, Y; Hao, H; He, G; Li, X; Liu, L; Liu, PZ; Liu, Z; Narasimhulu, CA; Parthasarathy, S; Xiao, Y; Xie, X; Zhang, J; Zhang, Q1
Barnado, A; Crofford, LJ; Oates, JC1
Aguirre, MA; Barbarroja, N; Collantes-Estevez, E; Cuadrado, MJ; Jimenez-Gomez, Y; López-Pedrera, C1
Gollavilli, PN; Gopoju, R; Karnewar, S; Kotamraju, S; Kumar, JM; Narra, SR; Vasamsetti, SB1
Cho, JH; Choi, JY; Kim, CD; Kim, YJ; Kim, YL; Oh, EJ; Oh, SH; Park, SH; Ryu, HM1
Ishisaka, A; Kanazawa, S; Kato, Y; Kettle, AJ; Kitamoto, N; Miura, Y; Naito, M; Oki, K; Ono, S; Suga, N1
Augé, N; Bando, Y; Marachet, MA; Muller, C; Nègre-Salvayre, A; Salvayre, R; Sanson, M; Sawa, Y; Thiers, JC; Vindis, C; Zarkovic, K1
Kishimoto, C; Kita, T; Lee, JD; Murayama, T; Shimada, K; Ueda, T; Uzui, H; Yokode, M1
Cui, JH; Li, YL; Li, ZX; Meng, XP; Wang, L; Wang, YW; Yin, CS1
Carrier, M; Farhat, N; Ferbeyre, G; Mallette, FA; Mamarbachi, AM; Perrault, LP; Thorin, E; Thorin-Trescases, N; Villeneuve, L; Voghel, G1
Jang, SW; Kim, J; Kim, Y; Ko, J; Sung, HJ1
Ieiri, I; Iwase, M; Kitazono, T; Matsuyama, N; Ohdo, S; Sonoki, K; Takata, Y1
Morrison, DC; Papasian, CJ; Qureshi, AA; Qureshi, N; Van Way, C; Vogel, SN1
Bernhard, D; Csordas, A; Henderson, B; Kind, M; Rossmann, A; Wick, G1
De Oliveira, MG; Estrela, HF; Franchini, KG; Krieger, MH; Laurindo, FR; Santos, KF; Santos, L; Shishido, SM; Spadari-Bratfisch, RC; Wanschel, AC1
Ikeda, D; Ishimaru, S; Itoh, N; Kamigaki, M; Nishimura, M; Ohira, H; Ohtsuka, Y; Sakaue, S; Tsujino, I1
Griffiths, HR; Luan, Y1
Chen, JW; Chen, YH; Chen, YL; Li, CY; Lin, FY; Lin, SJ; Tasi, JS; Wang, HJ; Yang, TL1
Carrier, M; Farhat, N; Fortier, A; Mamarbachi, AM; Perrault, LP; Thorin, E; Thorin-Trescases, N; Villeneuve, L; Voghel, G1

Reviews

4 review(s) available for acetylcysteine and Atherosclerosis

ArticleYear
[Acute Kidney Injury, AKI - Update 2018].
    Deutsche medizinische Wochenschrift (1946), 2018, Volume: 143, Issue:15

    Topics: Acetylcysteine; Acute Kidney Injury; Atherosclerosis; Clinical Trials as Topic; Contrast Media; Hematopoietic Stem Cell Transplantation; Humans; Multicenter Studies as Topic; Sodium Bicarbonate; Sodium Chloride; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2018
At the Bedside: Neutrophil extracellular traps (NETs) as targets for biomarkers and therapies in autoimmune diseases.
    Journal of leukocyte biology, 2016, Volume: 99, Issue:2

    Topics: Acetylcysteine; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Monoclonal; Antimalarials; Apoptosis; Atherosclerosis; Autoantigens; Autoimmune Diseases; Biomarkers; Deoxyribonuclease I; Extracellular Traps; Female; Humans; Hydrolases; Immunosuppressive Agents; Interferon-alpha; Lupus Erythematosus, Systemic; Molecular Targeted Therapy; Neutrophils; Pregnancy; Pregnancy Complications; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Thrombophilia; Thrombosis; Translational Research, Biomedical; Vitamin D

2016
Oxidative stress in the pathogenesis of atherothrombosis associated with anti-phospholipid syndrome and systemic lupus erythematosus: new therapeutic approaches.
    Rheumatology (Oxford, England), 2016, Volume: 55, Issue:12

    Topics: Acetylcysteine; Anticoagulants; Antioxidants; Antiphospholipid Syndrome; Atherosclerosis; Autoantibodies; beta 2-Glycoprotein I; Coagulants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Lupus Erythematosus, Systemic; Mitochondrial Diseases; Oxidative Stress; Reactive Oxygen Species; Recurrence; Thrombosis; Ubiquinone

2016
The proteasome: a central regulator of inflammation and macrophage function.
    Immunologic research, 2005, Volume: 31, Issue:3

    Topics: Acetylcysteine; Aging; Animals; Atherosclerosis; Cholesterol; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Neurodegenerative Diseases; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Shock, Hemorrhagic; Signal Transduction; Toll-Like Receptor 2

2005

Trials

1 trial(s) available for acetylcysteine and Atherosclerosis

ArticleYear
Telmisartan and N-acetylcysteine suppress group V secretory phospholipase A2 expression in TNFα-stimulated human endothelial cells and reduce associated atherogenicity.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:4

    Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Atherosclerosis; Benzimidazoles; Benzoates; Chemokine CCL2; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Group V Phospholipases A2; Human Umbilical Vein Endothelial Cells; Humans; Hypertension; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Middle Aged; RNA, Messenger; Telmisartan; Tumor Necrosis Factor-alpha

2012

Other Studies

26 other study(ies) available for acetylcysteine and Atherosclerosis

ArticleYear
The effect of per os colchicine administration in combination with fenofibrate and N-acetylcysteine on triglyceride levels and the development of atherosclerotic lesions in cholesterol-fed rabbits.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:24

    Topics: Acetylcysteine; Administration, Oral; Animals; Anti-Inflammatory Agents; Aorta; Atherosclerosis; C-Reactive Protein; Cholesterol; Colchicine; Drug Therapy, Combination; Fenofibrate; Hypolipidemic Agents; Interleukin-6; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rabbits; Triglycerides

2021
N‑acetyl cysteine prevents ambient fine particulate matter‑potentiated atherosclerosis via inhibition of reactive oxygen species‑induced oxidized low density lipoprotein elevation and decreased circulating endothelial progenitor cell.
    Molecular medicine reports, 2022, Volume: 26, Issue:1

    Topics: Acetylcysteine; Animals; Atherosclerosis; Endothelial Progenitor Cells; Lipoproteins, LDL; Mice; Particulate Matter; Reactive Oxygen Species

2022
N-acetylcysteine attenuates atherosclerosis progression in aging LDL receptor deficient mice with preserved M2 macrophages and increased CD146.
    Atherosclerosis, 2022, Volume: 357

    Topics: Acetylcysteine; Aging; Animals; Atherosclerosis; CD146 Antigen; Diet, High-Fat; Hyperlipidemias; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Reactive Oxygen Species; Receptors, LDL

2022
Helicobacter pylori infection selectively attenuates endothelial function in male mice
    Frontiers in cellular and infection microbiology, 2023, Volume: 13

    Topics: Acetylcysteine; Animals; Atherosclerosis; Endothelial Cells; Endothelium; Exosomes; Female; Helicobacter Infections; Helicobacter pylori; Male; Mice; Mice, Inbred C57BL; Reactive Oxygen Species

2023
Vanadium Derivative Exposure Promotes Functional Alterations of VSMCs and Consequent Atherosclerosis via ROS/p38/NF-κB-Mediated IL-6 Production.
    International journal of molecular sciences, 2019, Dec-04, Volume: 20, Issue:24

    Topics: Acetylcysteine; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cell Differentiation; Cell Movement; Cell Proliferation; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction; Vanadates

2019
N‑acetylcysteine inhibits atherosclerosis by correcting glutathione‑dependent methylglyoxal elimination and dicarbonyl/oxidative stress in the aorta of diabetic mice.
    Molecular medicine reports, 2021, Volume: 23, Issue:3

    Topics: Acetylcysteine; Animals; Aorta; Atherosclerosis; Diabetes Complications; Diabetes Mellitus, Experimental; Glutathione; Male; Mice; Mice, Knockout, ApoE; Oxidative Stress; Pyruvaldehyde

2021
KLF4 Upregulation in Atherosclerotic Thoracic Aortas: Exploring the Protective Effect of Colchicine-based Regimens in a Hyperlipidemic Rabbit Model.
    Annals of vascular surgery, 2022, Volume: 78

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Colchicine; Disease Models, Animal; Drug Therapy, Combination; Fibric Acids; Hyperlipidemias; Kruppel-Like Factor 4; Male; Plaque, Atherosclerotic; Rabbits; Up-Regulation

2022
Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice.
    Circulation research, 2013, Mar-29, Volume: 112, Issue:7

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Atherosclerosis; Cell Cycle Proteins; Cysteine; Female; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Free Radical Scavengers; Hematopoietic Stem Cells; Insulin; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Neutrophils; Nitrogen; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Tyrosine

2013
Arsenic augments the uptake of oxidized LDL by upregulating the expression of lectin-like oxidized LDL receptor in mouse aortic endothelial cells.
    Toxicology and applied pharmacology, 2013, Dec-15, Volume: 273, Issue:3

    Topics: Acetylcysteine; Animals; Aorta; Arsenites; Atherosclerosis; Caffeic Acids; Cell Line; Endothelial Cells; Lipoproteins, LDL; Mice; NF-kappa B; Phenylethyl Alcohol; Phosphorylation; Reactive Oxygen Species; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sodium Compounds; Up-Regulation

2013
Humic acid in drinking well water induces inflammation through reactive oxygen species generation and activation of nuclear factor-κB/activator protein-1 signaling pathways: a possible role in atherosclerosis.
    Toxicology and applied pharmacology, 2014, Jan-15, Volume: 274, Issue:2

    Topics: Acetylcysteine; Animals; Antioxidants; Atherosclerosis; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Dinoprostone; Drinking Water; Female; Gene Expression Regulation; Heme Oxygenase-1; Humic Substances; Inflammation; Interleukin-1beta; Membrane Proteins; Mice; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Reactive Oxygen Species; Signal Transduction; Taiwan; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2014
Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:9

    Topics: Acetylcysteine; Animals; Apolipoprotein A-I; Atherosclerosis; Bone Marrow Transplantation; Cell Division; Diet, Atherogenic; Disease Progression; Hematopoietic Stem Cells; Humans; Hypercholesterolemia; Leukocytosis; Lipoproteins, HDL; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Radiation Chimera; Reactive Oxygen Species; Receptors, LDL; Scavenger Receptors, Class B

2014
N-acetylcysteine inhibits in vivo oxidation of native low-density lipoprotein.
    Scientific reports, 2015, Nov-05, Volume: 5

    Topics: Acetylcysteine; Animals; Antioxidants; Atherosclerosis; Humans; Hyperlipidemias; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Reactive Oxygen Species; Receptors, LDL

2015
Resveratrol attenuates monocyte-to-macrophage differentiation and associated inflammation via modulation of intracellular GSH homeostasis: Relevance in atherosclerosis.
    Free radical biology & medicine, 2016, Volume: 96

    Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Buthionine Sulfoximine; Cell Differentiation; Glutathione; Homeostasis; Humans; Inflammation; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Monocytes; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate

2016
Hypoxanthine induces cholesterol accumulation and incites atherosclerosis in apolipoprotein E-deficient mice and cells.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:11

    Topics: Acetylcysteine; Allopurinol; Animals; Apolipoproteins E; Atherosclerosis; Cholesterol; Down-Regulation; Hep G2 Cells; Humans; Hydrogen Peroxide; Hypercholesterolemia; Hypoxanthine; Lipogenesis; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Plaque, Atherosclerotic; Up-Regulation

2016
A novel quinone derived from 5-hydroxyindoleacetic acid reacts with protein: Possible participation of oxidation of serotonin and its metabolite in the development of atherosclerosis.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: Acetylcysteine; Aged; Antibodies, Monoclonal; Aorta; Atherosclerosis; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydroxyindoleacetic Acid; Immunohistochemistry; Male; Microtomy; Peroxidase; Phenylenediamines; Quinones; Serotonin; Xanthine Oxidase

2016
Oxidized low-density lipoproteins trigger endoplasmic reticulum stress in vascular cells: prevention by oxygen-regulated protein 150 expression.
    Circulation research, 2009, Feb-13, Volume: 104, Issue:3

    Topics: Acetylcysteine; Aldehydes; Apoptosis; Atherosclerosis; Biomarkers; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endothelial Cells; Enzyme Inhibitors; Free Radical Scavengers; HSP70 Heat-Shock Proteins; Humans; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Ketocholesterols; Lipoproteins, LDL; Oxygen; Proteins; Stress, Physiological

2009
N-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:7

    Topics: Acetylcysteine; Animals; Apolipoproteins E; Atherosclerosis; Dietary Fats; Disease Models, Animal; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Severity of Illness Index; Superoxides

2009
[Inhibitory effect of N-acetylcysteine upon atherosclerotic processes in rabbit carotid].
    Zhonghua yi xue za zhi, 2009, Jul-14, Volume: 89, Issue:26

    Topics: Acetylcysteine; Animals; Atherosclerosis; Carotid Arteries; Disease Models, Animal; Lipoproteins, LDL; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Rabbits

2009
Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells.
    Mechanisms of ageing and development, 2010, Volume: 131, Issue:5

    Topics: Acetylcysteine; Aged; Atherosclerosis; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Endothelial Cells; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Oxidative Stress; Risk; Telomerase; Tumor Suppressor Protein p53

2010
N-acetyl cysteine suppresses the foam cell formation that is induced by oxidized low density lipoprotein via regulation of gene expression.
    Molecular biology reports, 2012, Volume: 39, Issue:3

    Topics: Acetylcysteine; Apolipoproteins E; Atherosclerosis; Biomarkers; Cell Line, Tumor; DNA Primers; Foam Cells; Gene Expression Profiling; Gene Expression Regulation; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Lipoproteins, LDL; Microarray Analysis; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction

2012
Cigarette smoke metal-catalyzed protein oxidation leads to vascular endothelial cell contraction by depolymerization of microtubules.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:9

    Topics: Acetylcysteine; Antioxidants; Atherosclerosis; Calcium; Catalysis; Cells, Cultured; Endothelial Cells; Humans; Interleukin-6; Interleukin-8; Metals; Microtubules; Nicotiana; Oxidative Stress; P-Selectin; Paclitaxel; Platelet Endothelial Cell Adhesion Molecule-1; Proteins; Smoke; Tubulin; Vasoconstriction

2005
Antiatherogenic effects of S-nitroso-N-acetylcysteine in hypercholesterolemic LDL receptor knockout mice.
    Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:1

    Topics: Acetylcysteine; Animals; Atherosclerosis; Blotting, Western; Hypercholesterolemia; Immunohistochemistry; Mice; Mice, Knockout; Nitric Oxide Donors; Nitric Oxide Synthase; Receptors, LDL

2006
Oxidative stress provokes atherogenic changes in adipokine gene expression in 3T3-L1 adipocytes.
    Biochemical and biophysical research communications, 2006, Jan-13, Volume: 339, Issue:2

    Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes; Adiponectin; Animals; Atherosclerosis; Gene Expression Regulation; Glucose Oxidase; Hydrogen Peroxide; Leptin; Mice; Oxidative Stress; Peptide Hormones; Plasminogen Activator Inhibitor 1; Resistin; RNA, Messenger

2006
Ceramides reduce CD36 cell surface expression and oxidised LDL uptake by monocytes and macrophages.
    Archives of biochemistry and biophysics, 2006, Jun-01, Volume: 450, Issue:1

    Topics: Acetylcysteine; Atherosclerosis; CD36 Antigens; Ceramides; Gene Expression Regulation; Humans; Lipoproteins, LDL; Macrophages; Proteasome Endopeptidase Complex; Protein Transport; RNA, Messenger; U937 Cells

2006
Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:12

    Topics: Acetophenones; Acetylcysteine; Animals; Aorta; Atherosclerosis; Cells, Cultured; Endotoxins; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation; Humans; Inflammation; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; NADPH Oxidases; Onium Compounds; Rabbits; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4

2006
Chronic treatment with N-acetyl-cystein delays cellular senescence in endothelial cells isolated from a subgroup of atherosclerotic patients.
    Mechanisms of ageing and development, 2008, Volume: 129, Issue:5

    Topics: Acetylcysteine; Aged; Antioxidants; Atherosclerosis; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Female; Humans; Lipid Peroxidation; Male; Mammary Arteries; Middle Aged; Organ Culture Techniques; Oxidative Stress; Telomerase

2008