acetylcysteine and Akinetic-Rigid Variant of Huntington Disease

acetylcysteine has been researched along with Akinetic-Rigid Variant of Huntington Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lindholm, D; Myöhänen, TT; Norrbacka, S1
Francis, PS; Frazier, AE; Gray, LJ; Hannan, AJ; McGee, SL; Renoir, T; Smith, ZM; Thorburn, DR; Wright, DJ1
Berk, M1
Kamboj, SS; Mehrotra, A; Sandhir, R; Sood, A1
Johnson, WM; Mieyal, JJ; Wilson-Delfosse, AL1
Arrigo, AP; Currie, RW; Firdaus, WJ; Giuliano, P; Kretz-Remy, C; Wyttenbach, A1
Carmichael, J; Furlong, RA; Narain, Y; Rankin, J; Rubinsztein, DC; Swartz, J; Wyttenbach, A1
Banks, A; Butterfield, DA; Fontaine, MA; Geddes, JW1
Boeddrich, A; Lehrach, H; Lueder, G; Lurz, R; Scherzinger, E; Waelter, S; Wanker, EE1
Avila, J; Hen, R; Hernández, F; Lucas, JJ; Martín-Aparicio, E; Yamamoto, A1

Reviews

1 review(s) available for acetylcysteine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Dysregulation of glutathione homeostasis in neurodegenerative diseases.
    Nutrients, 2012, Oct-09, Volume: 4, Issue:10

    Topics: Acetylcysteine; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Friedreich Ataxia; Glutathione; Homeostasis; Humans; Huntington Disease; Neurodegenerative Diseases; Parkinson Disease

2012

Other Studies

9 other study(ies) available for acetylcysteine and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington's disease.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:12

    Topics: Acetylcysteine; Biocatalysis; Cell Survival; Cysteine Proteinase Inhibitors; HeLa Cells; Humans; Huntingtin Protein; Huntington Disease; Peptides; Proline; Prolyl Oligopeptidases; Proteasome Endopeptidase Complex; Protein Aggregates; Protein Aggregation, Pathological; Serine Endopeptidases; Trinucleotide Repeats

2019
N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease.
    Translational psychiatry, 2015, Jan-06, Volume: 5

    Topics: Acetylcysteine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Transporter 2; Free Radical Scavengers; Gait; Huntington Disease; Mice; Mice, Transgenic; Mitochondria; Motor Activity; Organ Size; Oxidative Stress

2015
N-Acetylcysteine for Huntington's?
    The Australian and New Zealand journal of psychiatry, 2015, Volume: 49, Issue:11

    Topics: Acetylcysteine; Affect; Depression; Female; Humans; Huntington Disease; Middle Aged; Psychiatric Status Rating Scales; Quality of Life; Treatment Outcome

2015
N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease.
    Neuro-degenerative diseases, 2012, Volume: 9, Issue:3

    Topics: Acetylcysteine; Animals; Behavior, Animal; Caspase 3; Cognition; Corpus Striatum; Female; Free Radical Scavengers; Huntington Disease; Lipid Peroxidation; Mitochondria; Motor Skills; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Tumor Suppressor Protein p53

2012
Huntingtin inclusion bodies are iron-dependent centers of oxidative events.
    The FEBS journal, 2006, Volume: 273, Issue:23

    Topics: Acetylcysteine; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Deferoxamine; Exons; Heat-Shock Proteins; Huntington Disease; Inclusion Bodies; Iron; Microscopy, Confocal; Oxidation-Reduction; Phenanthridines; Rats; Recombinant Fusion Proteins

2006
Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6

    Topics: Acetylcysteine; Animals; Blotting, Western; Carrier Proteins; Cell Death; COS Cells; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Exons; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Huntington Disease; Immunohistochemistry; Multienzyme Complexes; Peptides; Plasmids; Proteasome Endopeptidase Complex; Rats; Temperature; Time Factors; Transfection; Tumor Cells, Cultured

2000
Effect of exogenous and endogenous antioxidants on 3-nitropionic acid-induced in vivo oxidative stress and striatal lesions: insights into Huntington's disease.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Acetylcysteine; Animals; Antioxidants; Cerebral Cortex; Corpus Striatum; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione; Huntington Disease; Male; Membrane Proteins; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Synaptosomes

2000
Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation.
    Molecular biology of the cell, 2001, Volume: 12, Issue:5

    Topics: 14-3-3 Proteins; Acetylcysteine; alpha-Synuclein; Carrier Proteins; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endoplasmic Reticulum Chaperone BiP; Exons; Heat-Shock Proteins; Humans; Huntingtin Protein; Huntington Disease; Immunoblotting; Inclusion Bodies; Membrane Proteins; Microscopy, Fluorescence; Models, Biological; Molecular Chaperones; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Peptide Fragments; Poly(A)-Binding Proteins; Proteasome Endopeptidase Complex; Proteins; Recombinant Fusion Proteins; RNA-Binding Proteins; Synucleins; T-Cell Intracellular Antigen-1; Transgenes; Tyrosine 3-Monooxygenase; Vimentin

2001
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Nov-15, Volume: 21, Issue:22

    Topics: Acetylcysteine; Animals; Behavior, Animal; Cell Death; Cell Survival; Cells, Cultured; Corpus Striatum; Cysteine Endopeptidases; Disease Models, Animal; Gene Silencing; Genes, Dominant; Huntingtin Protein; Huntington Disease; Locomotion; Macromolecular Substances; Mice; Mice, Neurologic Mutants; Multienzyme Complexes; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phenotype; Proteasome Endopeptidase Complex; Remission Induction; Tetracycline; Transgenes; Ubiquitin

2001