acetylcysteine and Acute Hepatic Failure

acetylcysteine has been researched along with Acute Hepatic Failure in 104 studies

Research

Studies (104)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (3.85)18.2507
2000's26 (25.00)29.6817
2010's60 (57.69)24.3611
2020's14 (13.46)2.80

Authors

AuthorsStudies
Ağın, H; Atakul, G; Çağlar, A; Çolak, M; Karaarslan, U; Soydan, E; Topal, S1
Aithal, GP; Alvarez-Alvarez, I; Andrade, RJ; Arikan, C; Atallah, E; Lucena, MI; Medina-Caliz, I; Niu, H1
Alkuraya, FS; Baker, JJ; Barcia, G; Baric, I; Braverman, N; Brennenstuhl, H; Burnyte, B; Christodoulou, J; Ciara, E; Coman, D; Darin, N; Das, AM; Della Marina, A; Distelmaier, F; Eklund, EA; Ersoy, M; Fang, W; Feichtinger, RG; Gaignard, P; Ganetzky, RD; Gonzales, E; Howard, C; Hughes, J; Kerr, M; Khan, A; Konstantopoulou, V; Kose, M; Landau, YE; Lenz, D; Margolis, MG; Mayr, JA; McFarland, R; Morrison, K; Mozer-Glassberg, Y; Müller, T; Murayama, K; Nicastro, E; Pechlaner, A; Pennisi, A; Peters, H; Piekutowska-Abramczuk, D; Prokisch, H; Rötig, A; Santer, R; Scaglia, F; Schiff, M; Schlieben, LD; Schröter, J; Shagrani, M; Sharrard, M; Soler-Alfonso, C; Staufner, C; Storey, I; Stormon, M; Taylor, RW; Teles, EL; Thorburn, DR; Vogel, GF; Wang, JS; Weghuber, D; Wortmann, S1
Balinski, A; Bower, R; Lee, M; McCarron, J1
Gupta, A; Gupta, M; Gupta, S; Jesrani, G; Sood, D1
Fedrizzi, M; Gál, J; Kovács, E; Maimeri, N; Morselli, F; Orlando, F; Pallanch, O; Székely, A1
Hynan, LS; Lee, WM; Rule, JA; Singh, S1
Hegarty, K; Monzon, B; Rech, MA1
Akakpo, JY; Jaeschke, H; Ramachandran, A1
Autry, MT; Fox, AN; Johnson, PN; Nation, BE1
Birrer, K; Carothers, C; Vo, M1
Nguyen, T; Siu, JT; Turgeon, RD1
Liabsuetrakul, T; Osatakul, S; Sriphongphankul, H1
Beitler, JR; Dzierba, AL; Furfaro, D; Muir, J; Shah, J1
Ari, B; Dawra, S; Kumar, A; Kumar, D; Manrai, M; Srivastava, S1
Bunchorntavakul, C; Reddy, KR3
Dalugama, C; Gawarammana, IB2
Serratrice, J; Spahr, L; Verdon, I1
Brok, J; Buckley, NA; Chiew, AL; Gluud, C1
Nguyen, V1
Liu, Z; Ye, Y1
Khan, R; Koppe, S1
Cao, P; Gong, X; Lin, Y; Liu, L; Luo, M; Wu, T; Yang, Q; Zhou, L1
Fontana, RJ; Hassan, A1
Moore, R; Nicholas, WA1
Ho, SM; Jiang, W; Khanal, T; Kim, K; Leung, YK; Timchenko, N1
Benesic, A; Berg, T; Gerbes, AL; Gerhardt, F; Henker, R; Maidhof, HP; Rademacher, S; Tillmann, HL; Trauer, H; Wiegand, J; Wittekind, C1
Amathieu, R; Chemit, M; Compagnon, P; Costentin, C; Dhonneur, G; Levesque, E; Merle, JC1
Brinkert, F; Fischer, L; Ganschow, R; Grabhorn, E; Herden, U; Hillebrand, G; Nielsen, D1
Bajaj, JS; Cheng, J; Lee, WM; Mirshahi, F; Reisch, J; Sanyal, AJ; Stravitz, RT1
Jayamanne, MD; Kankananarachchi, I; Senanayake, MP1
Chowdhury, R; Jayakumar, S; Karvellas, CJ; Ye, C1
Bass, S; Zook, N1
Koch, A; Streetz, KL; Tacke, F; Trautwein, C1
Bateman, DN; Butcher, I; Cooper, JG; Coyle, J; Dear, JW; Eddleston, M; Gray, A; Lewis, SC; Rodriguez, A; Sandilands, EA; Thanacoody, HK; Thomas, SH; Veiraiah, A; Vliegenthart, AD; Webb, DJ1
Burda, G; Gole, J; Hermon, M; Mostafa, G; Trittenwein, G; Vargha, R1
Eisenbach, C; Hoyler, B; Mogler, C; Sandig, C; Steinebrunner, N; Stremmel, W; Vittas, S1
Hu, J; Quan, Q; Ren, X; Sun, Z; Zhang, Q1
Abbas, Q; Haque, AU; Saleem, AF1
Jaeschke, H1
Kodali, S; McGuire, BM1
Hovda, LR; Schmid, RD1
Angus, P; Elliott, TR; Kannourakis, G; Symes, T1
Donnelly, MC; Hayes, PC; Simpson, KJ1
Fix, OK; Hameed, B; Karvellas, CJ; Lee, WM; Leung, AA; McGuire, BM; Schilsky, ML; Stravitz, RT; Tillman, H1
Sklar, GE; Tan, CJ1
Chung, RT; Davern, T; Davis, BC; Fontana, RJ; Lee, WM; McGuire, B; Reddy, R; Stravitz, RT; Tillman, H1
Darweesh, SK; El-Tahawy, MA; Ibrahim, MF1
Busuttil, RW; Chun, LJ; Hiatt, JR; Tong, MJ1
Bansal, S; Dhawan, A; Hughes, RD; Mieli-Vergani, G; Mitry, RR1
Capparelli, E; Davern, TJ; Hinson, JA; James, LP; Lee, WM; Letzig, L; Roberts, DW; Simpson, PM1
Athuraliya, TN; Jones, AL1
Davern, TJ; Fontana, RJ; Hynan, LS; Larson, AM; Lee, WM; McCashland, T; Murray, NG; Reisch, JS; Robuck, PR; Rossaro, L; Stravitz, RT1
Trotter, JF1
Kramer, DJ; Stravitz, RT1
Riordan, SM; Williams, R1
Mehrpour, O; Sanaei-Zadeh, H; Shadnia, S1
Bémeur, C; Butterworth, RF; Desjardins, P; Vaquero, J1
Ford, RM; Sakaria, SS; Subramanian, RM1
Babu, IR; Goessling, W; Lord, AM; North, TE; Tannenbaum, SR; Vedder, LM; Wishnok, JS; Zon, LI1
Lee, WM1
James, LP; Khandelwal, N; Larson, AM; Lee, WM; Sanders, C1
Bass, D; Mojtahed, A; Yeh, AM1
Butterworth, RF1
Borrelli, MJ; Brown, AT; Chaudhuri, S; Jambhekar, K; James, LP; McCullough, S; Ou, X; Pandey, T1
Cash, WJ; Iqbal, M; McCormick, PA; Sarwar, S1
Jalan, R; Mpabanzi, L1
Lee, JH; Lim, G1
Hosoya, J; Iseki, K; Shiraishi, T; Suzuki, T; Takahashi, N; Tominaga, A; Toyoguchi, T1
Adegboyega, PA; Ajuebor, MN; Aw, TY; Downs, I; Liu, J1
Choate, J; Emre, SH; Luczycki, SM; Maitta, RW; Wu, Y1
Alonso, E; Belle, SH; Bucuvalas, J; Dhawan, A; Doo, E; Elisofon, S; Horslen, S; Karpen, S; Kerkar, N; Lawlor, S; Lobritto, S; Lopez, MJ; Narkewicz, MR; Ng, V; Olio, DD; Rand, E; Robuck, PR; Rodriguez-Baez, N; Romero, R; Rosenthal, P; Rudnick, D; Schwarz, K; Shneider, BL; Squires, RH; Subbarao, G1
Boyajian, M; Cheerharan, M; Iorio, ML; Kaufman, SS; Reece-Stremtan, S1
Hadžić, N1
Garrard, AR; Hodgman, MJ1
Abeysekera, RA; Illangasekera, U; Jayalath, T; Kularatne, SA; Sandeepana, AG1
Hynan, LS; Lee, WM; Singh, S1
Höckerstedt, K; Isoniemi, H; Koivusalo, AM; Nuutinen, H; Vakkuri, A1
Abdollahi, M; Jalali, N; Pajoumand, A; Shadnia, S1
Sklar, GE; Subramaniam, M1
Dybowska, D; Kozielewicz, D; Nowak, W; Olczak, A1
Bozek, P; Greksák, M; Gvozdjáková, A; Kucharská, J; Nakano, M; Sumbalová, Z; Ulicná, O; Vancová, O1
Andrades, M; Dal-Pizzol, F; Martins, MR; Menna-Barreto, S; Moreira, JC; Quevedo, J; Reinke, A; Ritter, C; Rocha, J1
Chen, WJ; Fang, CC; Liu, YP; Ni, YH1
Davern, TJ; Fontana, RJ; Hinson, JA; James, LP; Lalani, E; Larson, AM; Lee, WM; Munoz, S; Polson, J; Shakil, AO1
Alvarez, M; Culebras, JM; González-Gallego, J; San-Miguel, B; Tuñón, MJ1
Howarth, ES; Venkat-Raman, N; Venkata-Krishnan, RV1
Khashab, M; Kwo, PY; Tector, AJ1
Assy, N; Gefen, H; Hussein, O; Schlesinger, S1
Draaisma, JM; Hameleers-Snijders, P; Hogeveen, M; Kramers, C; Smeitink, JA1
Brown, JM; Carpenter, AB; Terneus, MV; Valentovic, MA1
Balistreri, WF; Leonis, MA1
Bansal, S; Cheeseman, P; Dhawan, A; Kortsalioudaki, C; Mieli-Vergani, G; Taylor, RM1
Ajzenberg, N; Alvin, P; Dreyfus, M; Rey, C; Tchernia, G1
Bray, GP1
Fellay, M; Kehtari, R1
Montanini, S; Praticò, C; Sinardi, AU; Sinardi, D; Trimarchi, G1
Lee, WM; Ostapowicz, G1
Bakos, A; Hazai, E; Monostory, K; Vereczkey, L; Zacher, G1
Bondesen, S; Christensen, E; Ott, P; Schiødt, FV1

Reviews

34 review(s) available for acetylcysteine and Acute Hepatic Failure

ArticleYear
Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review.
    Drug safety, 2022, Volume: 45, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adrenal Cortex Hormones; Adult; Carnitine; Chemical and Drug Induced Liver Injury; Child; Drug-Related Side Effects and Adverse Reactions; Glutathione; Glycyrrhizic Acid; Humans; Infant, Newborn; Liver; Liver Failure, Acute; Retrospective Studies; S-Adenosylmethionine; Ursodeoxycholic Acid

2022
Role of N-acetylcysteine in liver injury due to dengue fever.
    Tropical doctor, 2023, Volume: 53, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Dengue; Humans; Liver Failure, Acute

2023
Factors improving mortality in critically ill patients with liver failure - A systematic review.
    Physiology international, 2023, Sep-05, Volume: 110, Issue:3

    Topics: Acetylcysteine; Adult; Critical Illness; Humans; Liver Cirrhosis; Liver Failure; Liver Failure, Acute

2023
Novel strategies for the treatment of acetaminophen hepatotoxicity.
    Expert opinion on drug metabolism & toxicology, 2020, Volume: 16, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Edetic Acid; Fomepizole; Hepatocytes; Humans; Liver Failure, Acute; Pyridoxal Phosphate

2020
N-acetylcysteine for non-paracetamol (acetaminophen)-related acute liver failure.
    The Cochrane database of systematic reviews, 2020, Dec-09, Volume: 12

    Topics: Acetylcysteine; Adolescent; Adult; Bias; Cause of Death; Child; Child, Preschool; Hepatic Encephalopathy; Humans; Infant; Infant, Newborn; Liver Failure, Acute; Liver Transplantation; Placebos; Prognosis; Randomized Controlled Trials as Topic

2020
Use of N-Acetylcysteine for Clozapine-Induced Acute Liver Injury: A Case Report and Literature Review.
    Journal of pharmacy practice, 2023, Volume: 36, Issue:2

    Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Clozapine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Liver Failure, Acute; Middle Aged

2023
Acute Liver Failure.
    Clinics in liver disease, 2017, Volume: 21, Issue:4

    Topics: Acetylcysteine; Brain Edema; Chemical and Drug Induced Liver Injury; Clinical Protocols; Critical Care; Disease Management; Diuretics, Osmotic; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Intracranial Hypertension; Liver Failure, Acute; Liver Transplantation; Mannitol; Saline Solution, Hypertonic; Time Factors

2017
Interventions for paracetamol (acetaminophen) overdose.
    The Cochrane database of systematic reviews, 2018, 02-23, Volume: 2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Cysteamine; Dimercaprol; Drug Overdose; Gastric Lavage; Humans; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Methionine; Randomized Controlled Trials as Topic

2018
Acetaminophen (APAP or N-Acetyl-p-Aminophenol) and Acute Liver Failure.
    Clinics in liver disease, 2018, Volume: 22, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Biomarkers; Humans; Liver Failure, Acute; Liver Transplantation

2018
Management of Amanita phalloides poisoning: A literature review and update.
    Journal of critical care, 2018, Volume: 46

    Topics: Acetylcysteine; Amanita; Amanitins; Antidotes; Bile Ducts; Charcoal; Diuresis; Gastric Lavage; Humans; Liver; Liver Failure, Acute; Liver Transplantation; Mushroom Poisoning; Penicillin G; Silymarin

2018
Modern Management of Acute Liver Failure.
    Gastroenterology clinics of North America, 2018, Volume: 47, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Biomarkers; Blood Coagulation Disorders; Brain Diseases; Free Radical Scavengers; Humans; Intracranial Hypertension; Liver Failure, Acute; Liver Transplantation; Monitoring, Physiologic; Mushroom Poisoning; Renal Replacement Therapy

2018
The diagnosis and management of idiosyncratic drug-induced liver injury.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:1

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Biomarkers; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Failure, Acute; Liver Transplantation; Randomized Controlled Trials as Topic; Risk Factors

2019
[Severe toxic acute liver failure: etiology and treatment].
    Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acute Kidney Injury; Anti-Infective Agents; Blood Coagulation Disorders; Chemical and Drug Induced Liver Injury; Cholestasis; Combined Modality Therapy; Diagnosis, Differential; Disease Management; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Illicit Drugs; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Mushroom Poisoning; Neurologic Examination; Occupational Diseases; Respiratory Insufficiency; Sepsis; Shock; Time Factors; Valproic Acid

2013
Fulminant viral hepatitis.
    Critical care clinics, 2013, Volume: 29, Issue:3

    Topics: Acetylcysteine; Adult; Brain Edema; Developing Countries; Female; Hepatectomy; Hepatitis, Viral, Human; Herpesviridae; Humans; Hypothermia, Induced; Immunocompromised Host; Intensive Care Units; Intubation, Intratracheal; Liver Failure, Acute; Liver Transplantation; Pregnancy; Pregnancy Complications, Infectious; Prognosis; Viral Hepatitis Vaccines

2013
Intravenous acetylcysteine for indications other than acetaminophen overdose.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2013, Sep-01, Volume: 70, Issue:17

    Topics: Acetaminophen; Acetylcysteine; Administration, Intravenous; Animals; Antidotes; Drug Overdose; Hepatitis, Alcoholic; Humans; Liver Failure, Acute

2013
Acetaminophen-related hepatotoxicity.
    Clinics in liver disease, 2013, Volume: 17, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antipyretics; Chemical and Drug Induced Liver Injury; Humans; Liver Failure, Acute; Risk Factors

2013
[Acute liver failure. Diagnosis and therapy].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2013, Volume: 108, Issue:8

    Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Liver Transplantation; Multiple Organ Failure; Nucleosides; Nucleotides; Organ Dysfunction Scores; Prognosis

2013
Efficacy and safety of acetylcysteine in "non-acetaminophen" acute liver failure: A meta-analysis of prospective clinical trials.
    Clinics and research in hepatology and gastroenterology, 2015, Volume: 39, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Administration, Oral; Clinical Trials as Topic; Free Radical Scavengers; Humans; Infusions, Intravenous; Liver Failure, Acute; Prospective Studies; Treatment Outcome

2015
Acetaminophen: Dose-Dependent Drug Hepatotoxicity and Acute Liver Failure in Patients.
    Digestive diseases (Basel, Switzerland), 2015, Volume: 33, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antidotes; Biomarkers; Cell Death; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Overdose; Free Radical Scavengers; Hepatocytes; Humans; Liver; Liver Failure, Acute; Mice

2015
Diagnosis and Management of Hepatic Encephalopathy in Fulminant Hepatic Failure.
    Clinics in liver disease, 2015, Volume: 19, Issue:3

    Topics: Acetylcysteine; Ammonia; Brain Edema; Free Radical Scavengers; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Intracranial Pressure; Lactulose; Liver Failure, Acute; Neuroimaging; Neuropsychological Tests; Nutritional Support; Rifamycins; Rifaximin

2015
The changing face of liver transplantation for acute liver failure: Assessment of current status and implications for future practice.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2016, Volume: 22, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Contraindications; Free Radical Scavengers; Humans; Liver Failure, Acute; Liver Transplantation; Prognosis; Quality of Life; Rare Diseases; Survival Rate; Treatment Outcome; Waiting Lists

2016
Acetaminophen hepatotoxicity and acute liver failure.
    Journal of clinical gastroenterology, 2009, Volume: 43, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adult; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Liver Failure, Acute; Liver Transplantation; Male; United Kingdom; United States

2009
Practical management of acute liver failure in the Intensive Care Unit.
    Current opinion in critical care, 2009, Volume: 15, Issue:2

    Topics: Acetylcysteine; Biopsy, Needle; Brain Edema; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Intensive Care Units; Liver Failure, Acute; Liver Transplantation; Renal Insufficiency; United States

2009
Management of acute liver failure.
    Nature reviews. Gastroenterology & hepatology, 2009, Volume: 6, Issue:9

    Topics: Acetylcysteine; Antiviral Agents; Hepatitis, Viral, Human; Humans; Liver Failure, Acute; Liver Transplantation; Multiple Organ Failure

2009
Critical care management of patients before liver transplantation.
    Transplantation reviews (Orlando, Fla.), 2010, Volume: 24, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Brain Edema; Drug Overdose; End Stage Liver Disease; Hepatopulmonary Syndrome; Homeostasis; Humans; Liver Failure, Acute; Liver Transplantation; Postoperative Period; Preoperative Care; Treatment Outcome

2010
Hepatic encephalopathy: a central neuroinflammatory disorder?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Animals; Brain Edema; Hepatic Encephalopathy; Humans; Hypothermia, Induced; Liver Failure, Acute; Minocycline

2011
Neurological complications of acute liver failure: pathophysiological basis of current management and emerging therapies.
    Neurochemistry international, 2012, Volume: 60, Issue:7

    Topics: Acetylcysteine; Brain Edema; Combined Modality Therapy; Humans; Intracranial Pressure; Liver Failure, Acute

2012
Emergency ABO-incompatible liver transplant secondary to fulminant hepatic failure: outcome, role of TPE and review of the literature.
    Journal of clinical apheresis, 2012, Volume: 27, Issue:6

    Topics: ABO Blood-Group System; Acetaminophen; Acetylcysteine; Adult; Antibodies, Monoclonal, Murine-Derived; Antidepressive Agents; Biliary Tract Surgical Procedures; Blood Group Incompatibility; Cholestasis; Combined Modality Therapy; Depressive Disorder; Emergencies; Female; Graft Rejection; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Liver Failure, Acute; Liver Function Tests; Plasma Exchange; Postoperative Complications; Rituximab; Stents; Suicide, Attempted

2012
A review of acetaminophen poisoning.
    Critical care clinics, 2012, Volume: 28, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Drug Interactions; Drug Overdose; Ethanol; Humans; Liver Failure, Acute; Liver Transplantation; Nomograms; Time Factors

2012
Acetylcysteine treatment for non-acetaminophen-induced acute liver failure.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:3

    Topics: Acetylcysteine; Free Radical Scavengers; Humans; Injections, Intravenous; Liver Failure, Acute; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2004
Epidemiology of acute liver failure.
    Current gastroenterology reports, 2007, Volume: 9, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Drug-Related Side Effects and Adverse Reactions; Free Radical Scavengers; Hepatitis, Autoimmune; Hepatitis, Viral, Human; Humans; Liver Failure, Acute; Liver Transplantation; Metabolic Diseases; Neoplasms; Prognosis; Vascular Diseases

2007
[Focus: fulminant and subfulminant hepatic insufficiency].
    Revue medicale de la Suisse romande, 1996, Volume: 116, Issue:6

    Topics: Acetylcysteine; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Critical Care; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Hypoxia; Liver Failure, Acute; Liver Transplantation; Prognosis

1996
Acute hepatic failure: a Western perspective.
    Journal of gastroenterology and hepatology, 2000, Volume: 15, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Health Care Costs; Hepatitis, Viral, Human; Humans; Liver Failure, Acute; Liver Transplantation; Prevalence; Prostaglandins

2000
[About paracetamol again].
    Orvosi hetilap, 2001, Feb-18, Volume: 142, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Cimetidine; Drug Overdose; Humans; Liver; Liver Failure, Acute

2001

Trials

7 trial(s) available for acetylcysteine and Acute Hepatic Failure

ArticleYear
Effects of N-acetylcysteine on cytokines in non-acetaminophen acute liver failure: potential mechanism of improvement in transplant-free survival.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:9

    Topics: Acetylcysteine; Cytokines; Enzyme-Linked Immunosorbent Assay; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Logistic Models

2013
Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial.
    Lancet (London, England), 2014, Feb-22, Volume: 383, Issue:9918

    Topics: Acetaminophen; Acetylcysteine; Adult; Aged; Alanine Transaminase; Antiemetics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Liver Failure, Acute; Male; Middle Aged; Nausea; Ondansetron; Poisoning; Treatment Outcome; United Kingdom; Vomiting

2014
[Acute liver failure -- does N-acetylcysteine ​​improve the prognosis in children?].
    Zeitschrift fur Gastroenterologie, 2013, Volume: 51, Issue:8

    Topics: Acetylcysteine; Child; Child, Preschool; Combined Modality Therapy; Female; Free Radical Scavengers; Humans; Infant; Infant, Newborn; Liver Failure, Acute; Liver Transplantation; Male; Prevalence; Prognosis; Risk Assessment; Survival Rate; Treatment Outcome

2013
Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure.
    Gastroenterology, 2009, Volume: 137, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Survival Rate; Young Adult

2009
Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:4

    Topics: Acetylcysteine; Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Liver Failure, Acute; Liver Transplantation; Male; Severity of Illness Index; Survival Rate; Treatment Outcome

2013
Improvements in hepatic serological biomarkers are associated with clinical benefit of intravenous N-acetylcysteine in early stage non-acetaminophen acute liver failure.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:5

    Topics: Acetylcysteine; Adult; Biomarkers; Coma; Double-Blind Method; Female; Free Radical Scavengers; Humans; Infusions, Intravenous; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Male; Prospective Studies

2013
Use of acetylcysteine as the life-saving antidote in Amanita phalloides (death cap) poisoning. Case report on 11 patients.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:12

    Topics: Acetylcysteine; Adolescent; Adult; Aged; Alanine Transaminase; Amanita; Antidotes; Aspartate Aminotransferases; Biomarkers; Child; Child, Preschool; Female; Humans; L-Lactate Dehydrogenase; Liver Failure, Acute; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mushroom Poisoning; Renal Insufficiency; Time Factors

1999

Other Studies

63 other study(ies) available for acetylcysteine and Acute Hepatic Failure

ArticleYear
The association between N-acetylcysteine treatment and hepatic healing in patients with non-acetaminophen-induced liver injury in pediatric intensive care: A single-center retrospective study.
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2022, Volume: 29, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Child; Critical Care; Female; Humans; Liver Failure, Acute; Male; Retrospective Studies; Transaminases; Treatment Outcome

2022
Genotypic and phenotypic spectrum of infantile liver failure due to pathogenic TRMU variants.
    Genetics in medicine : official journal of the American College of Medical Genetics, 2023, Volume: 25, Issue:6

    Topics: Acetylcysteine; Adolescent; Child; Child, Preschool; Humans; Infant; Liver Failure; Liver Failure, Acute; Mitochondrial Proteins; Mutation; Retrospective Studies; tRNA Methyltransferases; Young Adult

2023
Intravenous acetaminophen associated with acute liver failure.
    BMJ case reports, 2022, Nov-22, Volume: 15, Issue:11

    Topics: Acetaminophen; Acetylcysteine; Brain Diseases; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Liver Failure, Acute

2022
Changes in alpha-foetoprotein and Gc-globulin in relation to outcomes in non-acetaminophen acute liver failure.
    Liver international : official journal of the International Association for the Study of the Liver, 2019, Volume: 39, Issue:12

    Topics: Acetylcysteine; Adolescent; Adult; Aged; alpha-Fetoproteins; Biomarkers; Female; Humans; Liver Failure, Acute; Male; Middle Aged; Retrospective Studies; Vitamin D-Binding Protein; Young Adult

2019
A knack for "NAC": Treatment for heat stroke induced acute liver injury.
    The American journal of emergency medicine, 2020, Volume: 38, Issue:4

    Topics: Acetylcysteine; Emergency Service, Hospital; Heat Stroke; Humans; Infusions, Intravenous; Liver Failure, Acute; Male; Young Adult

2020
Possible role for acetylcysteine as a treatment for acute liver failure secondary to antitubercular medication use.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, 09-04, Volume: 77, Issue:18

    Topics: Acetylcysteine; Administration, Oral; Adult; Antidotes; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Failure, Acute; Tuberculosis

2020
Acetylcysteine for the Treatment of Suspected Remdesivir-Associated Acute Liver Failure in COVID-19: A Case Series.
    Pharmacotherapy, 2020, Volume: 40, Issue:11

    Topics: Acetylcysteine; Adenosine Monophosphate; Aged; Aged, 80 and over; Alanine; Antiviral Agents; COVID-19 Drug Treatment; Fatal Outcome; Female; Humans; Liver Failure, Acute; Liver Function Tests; SARS-CoV-2; Treatment Outcome

2020
Clinical Outcomes of Children Diagnosed Dengue-Associated Acute Liver Failure with or without N-Acetylcysteine Treatment: A Retrospective Cohort Study.
    Journal of tropical pediatrics, 2021, 05-17, Volume: 67, Issue:2

    Topics: Acetylcysteine; Child; Dengue; Humans; Liver Failure, Acute; Microcirculation; Retrospective Studies; Thailand

2021
Rodenticide-induced acute liver failure - Uncommon presentation of commonly available poison.
    Tropical doctor, 2021, Volume: 51, Issue:4

    Topics: Acetylcysteine; Animals; Humans; Liver Failure, Acute; Phosphorus; Poisons; Rats; Rodenticides

2021
Dengue hemorrhagic fever complicated with acute liver failure: a case report.
    Journal of medical case reports, 2017, Dec-08, Volume: 11, Issue:1

    Topics: Acetylcysteine; Blood Transfusion; Free Radical Scavengers; Humans; Liver Failure, Acute; Male; Middle Aged; Severe Dengue

2017
[N-acetylcysteine : effective treatment in severe alcoholic hepatitis ?]
    Revue medicale suisse, 2018, Jan-17, Volume: 14, Issue:590

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antiviral Agents; Drug Overdose; Hepatitis, Alcoholic; Humans; Liver Failure, Acute

2018
Calculated decisions: King's College Criteria for Acetaminophen Toxicity
    Emergency medicine practice, 2018, Apr-01, Volume: 20, Issue:4 Suppl

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Biomarkers; Decision Making; Humans; Liver Failure, Acute; Liver Transplantation; Prognosis; Sensitivity and Specificity; Time Factors

2018
Tamoxifen Prevents D-galactosamine/Lipopolysaccharide-Induced Murine Acute Hepatic Failure through Inhibition of Oxidative Stress and Mmd-2 Upregulation.
    Immunological investigations, 2018, Volume: 47, Issue:6

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Antigens, Differentiation; Antioxidants; Aspartate Aminotransferases; Catalase; Galactosamine; Glutathione Peroxidase; Lipopolysaccharides; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Oxidative Stress; Superoxide Dismutase; Tamoxifen; Up-Regulation

2018
Lessons learnt from managing a case of dengue hemorrhagic fever complicated with acute liver failure and acute kidney injury: a case report.
    Journal of medical case reports, 2018, Aug-08, Volume: 12, Issue:1

    Topics: Acetylcysteine; Acidosis, Lactic; Acute Kidney Injury; Adult; Antioxidants; Diabetes Mellitus, Type 2; Erythrocyte Transfusion; Female; Fluid Therapy; Humans; Liver Failure, Acute; Renal Replacement Therapy; Severe Dengue

2018
Using the 150 rule to prevent hepatotoxicity from acetaminophen.
    JAAPA : official journal of the American Academy of Physician Assistants, 2019, Volume: 32, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Diagnosis, Differential; Disease Progression; Drug Overdose; Female; Humans; Liver Failure, Acute

2019
NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Epigenesis, Genetic; Hep G2 Cells; Humans; Liver Failure, Acute; Mice; Mice, Knockout; Orphan Nuclear Receptors; RNA, Long Noncoding; Signal Transduction; Tumor Suppressor Protein p53

2019
Iberogast-Induced Acute Liver Failure-Reexposure and In Vitro Assay Support Causality.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:8

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Causality; Dipyrone; Fatal Outcome; Female; Free Radical Scavengers; Gastrointestinal Diseases; Glucocorticoids; Hepatocytes; Humans; In Vitro Techniques; Liver Failure, Acute; Liver Transplantation; Middle Aged; Monocytes; Plant Extracts; Prednisolone

2019
Successful outcome of severe Amanita phalloides poisoning in children.
    Pediatric transplantation, 2013, Volume: 17, Issue:6

    Topics: Acetylcysteine; Amanita; Antioxidants; Child; Child, Preschool; Critical Care; Female; Follow-Up Studies; Humans; Infant; Liver Failure, Acute; Liver Transplantation; Male; Mushroom Poisoning; Prognosis; Retrospective Studies; Silybin; Silymarin; Treatment Outcome

2013
N-acetylcysteine in children with acute liver failure complicating dengue viral infection.
    The Ceylon medical journal, 2013, Volume: 58, Issue:2

    Topics: Acetylcysteine; Child; Dengue; Dengue Virus; Humans; Liver Failure, Acute; Retrospective Studies

2013
Treatment with N-acetylcystein and total plasma exchange for extracorporeal liver support in children with paracetamol intoxication.
    Klinische Padiatrie, 2014, Volume: 226, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Ammonia; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Child, Preschool; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Hypothermia, Induced; Infant; Intensive Care Units, Pediatric; Liver Failure, Acute; Liver Function Tests; Plasma; Plasma Exchange; Respiratory Tract Infections

2014
Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse.
    BMC gastroenterology, 2014, Aug-19, Volume: 14

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Disease Models, Animal; Free Radical Scavengers; Interleukin-1beta; Lactate Dehydrogenases; Liver; Liver Failure, Acute; Mice; Mice, Inbred BALB C; Neostigmine; Tumor Necrosis Factor-alpha

2014
Use of N-acetylcysteine in children with fulminant hepatic failure caused by acute viral hepatitis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:5

    Topics: Acetylcysteine; Acute Disease; Adolescent; Analysis of Variance; Antiviral Agents; Child; Child, Preschool; Female; Hepatitis, Viral, Human; Humans; Infant; Jaundice; Liver Failure, Acute; Liver Function Tests; Male; Retrospective Studies; Risk Factors; Treatment Outcome; Vomiting

2015
Acute Hepatic Failure in a Dog after Xylitol Ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:2

    Topics: Acetylcysteine; Animals; Animals, Inbred Strains; Antidotes; Biomarkers; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Disseminated Intravascular Coagulation; Dogs; Hypoglycemia; Liver Failure, Acute; Male; S-Adenosylmethionine; Sweetening Agents; Treatment Outcome; Xylitol

2016
Resolution of norfloxacin-induced acute liver failure after N-acetylcysteine therapy: further support for the use of NAC in drug-induced ALF?
    BMJ case reports, 2016, Jan-06, Volume: 2016

    Topics: Acetylcysteine; Aged; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Liver Failure, Acute; Norfloxacin

2016
Acute liver injury and acute liver failure from mushroom poisoning in North America.
    Liver international : official journal of the International Association for the Study of the Liver, 2016, Volume: 36, Issue:7

    Topics: Acetylcysteine; Adult; Amanitins; Chemical and Drug Induced Liver Injury; Cohort Studies; Female; Humans; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Mushroom Poisoning; North America; Penicillins; Registries; Silybin; Silymarin

2016
Characterisation and outcomes of adult patients with paracetamol overdose presenting to a tertiary hospital in Singapore.
    Singapore medical journal, 2017, Volume: 58, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Anaphylaxis; Drug Overdose; Female; Humans; Liver; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Singapore; Suicide, Attempted; Tertiary Care Centers; Treatment Outcome; Young Adult

2017
Heat stroke leading to acute liver injury & failure: A case series from the Acute Liver Failure Study Group.
    Liver international : official journal of the International Association for the Study of the Liver, 2017, Volume: 37, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Adult; Female; Heat Stroke; Humans; Liver; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Prospective Studies; Registries; Renal Replacement Therapy; Rhabdomyolysis; United States

2017
Effect of N-Acetylcysteine on Mortality and Liver Transplantation Rate in Non-Acetaminophen-Induced Acute Liver Failure: A Multicenter Study.
    Clinical drug investigation, 2017, Volume: 37, Issue:5

    Topics: Acetaminophen; Acetylcysteine; Administration, Intravenous; Adult; Cohort Studies; Female; Hospitalization; Humans; Length of Stay; Liver Failure, Acute; Liver Transplantation; Male; Middle Aged; Mortality; Prospective Studies; Young Adult

2017
In vitro effects of sera from children with acute liver failure on metabolic and synthetic activity of cryopreserved human hepatocytes.
    Journal of pediatric gastroenterology and nutrition, 2009, Volume: 48, Issue:5

    Topics: Acetylcysteine; Adolescent; Cells, Cultured; Child; Child, Preschool; Cryopreservation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Free Radical Scavengers; Hepatocytes; Humans; Infant; Liver Failure, Acute; Male; Proteins; Serum

2009
Pharmacokinetics of acetaminophen-protein adducts in adults with acetaminophen overdose and acute liver failure.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Antidotes; Bayes Theorem; Benzoquinones; Biomarkers; Biotransformation; Databases as Topic; Drug Overdose; Female; Half-Life; Humans; Imines; Liver Failure, Acute; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Models, Statistical; Nonlinear Dynamics; Young Adult

2009
Prolonged N-acetylcysteine therapy in late acetaminophen poisoning associated with acute liver failure--a need to be more cautious?
    Critical care (London, England), 2009, Volume: 13, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antidotes; Drug Administration Schedule; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Liver Failure, Acute; Mice

2009
Liver: Management of non-acetaminophen-induced ALF.
    Nature reviews. Gastroenterology & hepatology, 2010, Volume: 7, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Free Radical Scavengers; Humans; Liver Failure, Acute; Liver Transplantation; Randomized Controlled Trials as Topic

2010
Late extensive intravenous administration of N-acetylcysteine can reverse hepatic failure in acetaminophen overdose.
    Human & experimental toxicology, 2011, Volume: 30, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Analgesics, Non-Narcotic; Antidotes; Chemical and Drug Induced Liver Injury; Delayed Diagnosis; Drug Overdose; Free Radical Scavengers; Humans; Infusions, Intravenous; Intensive Care Units; Liver Failure, Acute; Male; Treatment Outcome

2011
N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms.
    Metabolic brain disease, 2010, Volume: 25, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Azoxymethane; Brain Edema; Carcinogens; Cytokines; Disease Models, Animal; Hepatic Encephalopathy; Inflammation; Inflammation Mediators; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Oxidative Stress

2010
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Oct-05, Volume: 107, Issue:40

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Animals, Genetically Modified; Chemical and Drug Induced Liver Injury; Dinoprostone; Genes, Reporter; Glutathione; Liver; Liver Failure, Acute; Proteome; Signal Transduction; Zebrafish

2010
Commentary.
    Clinical chemistry, 2011, Volume: 57, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Bilirubin; Diagnosis, Differential; False Positive Reactions; Female; Humans; Liver Failure, Acute

2011
Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Bilirubin; Chemical and Drug Induced Liver Injury; Drug Overdose; Female; Free Radical Scavengers; Humans; Liver Failure, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Severity of Illness Index; Survival Rate; Transaminases

2011
Acute liver failure and aplastic anemia in an 11-year-old girl.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:8

    Topics: Acetylcysteine; Anemia, Aplastic; Antilymphocyte Serum; Bilirubin; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Liver Failure, Acute; Methylprednisolone Hemisuccinate; Platelet Transfusion; Prednisone; Transaminases; Treatment Outcome; Vitamin K

2011
Correlation of MRI findings to histology of acetaminophen toxicity in the mouse.
    Magnetic resonance imaging, 2012, Volume: 30, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Animals; Antidotes; Expectorants; Liver Failure, Acute; Magnetic Resonance Imaging; Male; Mice; Reproducibility of Results; Sensitivity and Specificity; Statistics as Topic; Treatment Outcome

2012
Paracetamol overdose: the liver unit perspective.
    Irish journal of medical science, 2012, Volume: 181, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Chemical and Drug Induced Liver Injury; Drug Overdose; Early Diagnosis; Humans; Liver Failure, Acute; Liver Transplantation; Time Factors

2012
N-acetylcysteine in children with dengue-associated liver failure: a case report.
    Journal of tropical pediatrics, 2012, Volume: 58, Issue:5

    Topics: Acetylcysteine; Administration, Intravenous; Antiviral Agents; Child; Dengue; Dengue Virus; Humans; Immunoglobulin G; Immunoglobulin M; Liver Failure, Acute; Liver Function Tests; Male; Prognosis; Transaminases; Treatment Outcome

2012
[Study of the serum concentrations of acetaminophen overdose].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2012, Volume: 25, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Liver Failure, Acute; Male; Middle Aged; Prescription Drug Misuse; Young Adult

2012
The ROS scavenger, NAC, regulates hepatic Vα14iNKT cells signaling during Fas mAb-dependent fulminant liver failure.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Acetylcysteine; Analysis of Variance; Animals; Antibodies, Monoclonal; Apoptosis; Blotting, Western; Fas Ligand Protein; Flow Cytometry; Free Radical Scavengers; Glutathione; In Situ Nick-End Labeling; Interferon-gamma; Liver; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Knockout; Natural Killer T-Cells; Reactive Oxygen Species; Signal Transduction

2012
Acute liver failure following cleft palate repair: a case of therapeutic acetaminophen toxicity.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2013, Volume: 50, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Chemical and Drug Induced Liver Injury; Cleft Palate; Humans; Infusions, Intravenous; Liver Failure, Acute

2013
Challenging the dogmas; the NAC tie.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:4

    Topics: Acetylcysteine; Female; Humans; Liver Failure, Acute; Male

2013
Successful use of intravenous N-acetylcysteine in dengue haemorrhagic fever with acute liver failure.
    The Ceylon medical journal, 2012, Volume: 57, Issue:4

    Topics: Acetylcysteine; Administration, Intravenous; Female; Free Radical Scavengers; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Middle Aged; Severe Dengue; Treatment Outcome

2012
[Without liver transplantation paracetamol intoxication is often be lethal, in spite of N-acetylcysteine therapy].
    Duodecim; laaketieteellinen aikakauskirja, 2002, Volume: 118, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Drug Overdose; Humans; Liver Failure, Acute; Liver Transplantation; Prognosis; Treatment Outcome

2002
Successful treatment of acetaminophen overdose associated with hepatic failure.
    Human & experimental toxicology, 2003, Volume: 22, Issue:8

    Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Antidotes; Drug Overdose; Female; Humans; Liver; Liver Failure, Acute

2003
Acute hepatic failure in the course of alcohol-paracetamol syndrome--case report.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9 Suppl 3

    Topics: Acetaminophen; Acetylcysteine; Ethanol; Humans; Liver Failure, Acute; Male; Middle Aged; Poisoning

2003
Regeneration of coenzyme Q9 redox state and inhibition of oxidative stress by Rooibos tea (Aspalathus linearis) administration in carbon tetrachloride liver damage.
    Physiological research, 2004, Volume: 53, Issue:5

    Topics: Acetylcysteine; Animals; Antioxidants; Aspalathus; Beverages; Carbon Tetrachloride; Liver Failure, Acute; Liver Regeneration; Male; Oxidation-Reduction; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Treatment Outcome; Ubiquinone

2004
Protective effect of N-acetylcysteine and deferoxamine on carbon tetrachloride-induced acute hepatic failure in rats.
    Critical care medicine, 2004, Volume: 32, Issue:10

    Topics: Acetylcysteine; Animals; Antioxidants; Carbon Tetrachloride; Deferoxamine; Hydrocarbons; Inflammation; Liver; Liver Failure, Acute; Male; Models, Animal; Necrosis; Oxidative Stress; Rats; Rats, Wistar

2004
Fulminant hepatic failure due to chronic acetaminophen intoxication in an infant.
    The American journal of emergency medicine, 2005, Volume: 23, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Chronic Disease; Emergency Medicine; Female; Humans; Infant; Liver Failure, Acute; Poisoning; Treatment Outcome

2005
Measurement of serum acetaminophen-protein adducts in patients with acute liver failure.
    Gastroenterology, 2006, Volume: 130, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Blood Proteins; Chromatography, High Pressure Liquid; Female; Humans; Liver Failure, Acute; Male; Middle Aged; Poisoning

2006
N-acetyl-cysteine protects liver from apoptotic death in an animal model of fulminant hepatic failure.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:11

    Topics: Acetylcysteine; Animals; Animals, Inbred Strains; Antioxidants; Apoptosis; Caliciviridae Infections; Disease Models, Animal; Hemorrhagic Disease Virus, Rabbit; Hepatocytes; Liver; Liver Failure, Acute; Oxidative Stress; Rabbits

2006
Successful pregnancy outcome following maternal intravenous immunoglobulin treatment in a woman with recurrent perinatal haemochromatosis.
    Prenatal diagnosis, 2006, Volume: 26, Issue:13

    Topics: Acetylcysteine; Adult; Deferoxamine; Diagnosis, Differential; Female; Ferritins; Fetal Diseases; Free Radical Scavengers; Gestational Age; Hemochromatosis; Humans; Hydrops Fetalis; Infant, Newborn; Live Birth; Liver Failure, Acute; Pregnancy; Recurrence; Treatment Outcome; Vitamin E; Vitamin K

2006
The beneficial effect of N-acetylcysteine and ciprofloxacin therapy on the outcome of ischemic fulminant hepatic failure.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:12

    Topics: Acetylcysteine; Ciprofloxacin; Drug Therapy, Combination; Follow-Up Studies; Free Radical Scavengers; Humans; Ischemia; Liver; Liver Failure, Acute; Male; Middle Aged; Nucleic Acid Synthesis Inhibitors

2007
[Risk of acute hepatic insufficiency in children due to chronic accidental overdose of paracetamol (acetaminophen)].
    Nederlands tijdschrift voor geneeskunde, 2007, Apr-21, Volume: 151, Issue:16

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Child, Preschool; Drug Overdose; Female; Free Radical Scavengers; Humans; Liver; Liver Failure, Acute; Prognosis; Transaminases

2007
Comparison of S-adenosyl-L-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose.
    Toxicology, 2008, Feb-03, Volume: 244, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Aldehydes; Analysis of Variance; Animals; Blotting, Western; Drug Overdose; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Microscopy, Polarization; Organ Size; Protein Carbonylation; S-Adenosylmethionine; Time Factors

2008
Is there a "NAC" to treating acute liver failure in children?
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008, Volume: 14, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Child; Free Radical Scavengers; Humans; Injections, Intravenous; Liver Failure, Acute

2008
Safety and efficacy of N-acetylcysteine in children with non-acetaminophen-induced acute liver failure.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008, Volume: 14, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Liver Failure, Acute; Male; Retrospective Studies; Survival Rate; Treatment Outcome; United Kingdom

2008
[Acute liver failure caused by paracetamol: should treatment with N-acetylcysteine be prolonged?].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1995, Volume: 2, Issue:7

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Liver Failure, Acute

1995
Liver failure induced by paracetamol.
    BMJ (Clinical research ed.), 1993, Jan-16, Volume: 306, Issue:6871

    Topics: Acetaminophen; Acetylcysteine; Drug Overdose; Humans; Liver Failure, Acute

1993
The value of plasma acetaminophen half-life in antidote-treated acetaminophen overdosage.
    Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analysis of Variance; Antidotes; Drug Overdose; Female; Half-Life; Hepatic Encephalopathy; Humans; Liver Failure, Acute; Male; Middle Aged; Prospective Studies; Statistics, Nonparametric

2002