acetylcysteine has been researched along with Acute Brain Injuries in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 9 (28.13) | 29.6817 |
| 2010's | 16 (50.00) | 24.3611 |
| 2020's | 6 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, S; Gao, W; Gao, YX; Liao, H; Pang, T; Qiu, WW; Wang, YJ; Wang, YY; Xu, Y; Xu, YZ; Yang, LF; Yu, LG; Zhang, LY | 1 |
| André, C; Curioni, CC; da Silva, ACF; de Velasco, PC; Lamarca, F; Mocellin, MC; Ribas, SA; Tavares, MDS | 1 |
| Bitsina, C; Chatzisotiriou, A; Dandi, E; Kesidou, E; Spandou, E; Tata, DA; Theotokis, P | 1 |
| Beloosesky, R; Ginsberg, Y; Gutzeit, O; Khatib, N; Ross, MG; Weiner, Z; Zmora, O | 1 |
| Aceti, A; Austin, T; Corvaglia, L; Faldella, G; Martini, S | 1 |
| Beloosesky, R; Boulos, S; Fainaru, O; Ginsberg, Y; Gutzeit, O; Khatib, N; Millo, Z; Ross, MG; Segal, L; Weiner, Z; Zmora, O | 1 |
| Acosta, G; Andrews, KD; Cao, J; Dietrich, AD; Liu, Z; Lu, KH; Lungwitz, EA; Majumdar, S; Race, NS; Shekhar, A; Shi, R; Truitt, WA; Vega Alvarez, SM; Warner, TR | 1 |
| Beloosesky, R; Efrat, S; Ginsberg, Y; Khatib, N; Mordechai, H; Ross, MG; Sharabi, H; Tamar, BK; Weiner, Z | 1 |
| Liu, BH; Wu, W; Xia, XD; Xie, CL; Zhang, YM | 1 |
| Antkiewicz-Michaluk, L; Nalepa, I; Romańska, I; Wąsik, A; Zelek-Molik, A | 1 |
| Beloosesky, R; Ginsberg, Y; Itskovitz-Eldor, J; Khatib, N; Maravi, N; Ross, MG; Weiner, Z | 1 |
| Abdel Baki, SG; Bergold, PJ; Dash, P; Ershova, A; Grill, RJ; Grin'kina, NM; Haber, M; Irizarry, R; Orsi, S | 1 |
| Baumgartner, WA; Beaty, CA; Blue, ME; Johnston, MV; Kambhampati, SP; Kannan, RM; Kannan, S; Lesniak, WG; Mishra, MK; Troncoso, JC; Wilson, MA; Zhang, F | 1 |
| Nazıroğlu, M; Senol, N; Yürüker, V | 1 |
| Balaban, CD; Baratz-Goldstein, R; Eakin, K; Hoffer, BJ; Hoffer, ME; Lockwood, M; Miller, J; Pick, CG; Zindel, O | 1 |
| Goldstein, GA; Pandya, JD; Patel, SP; Pauly, JR; Rabchevsky, AG; Readnower, RD; Sullivan, PG; Yonutas, HM | 1 |
| Ghazizadeh, V; Nazıroğlu, M; Senol, N; Yürüker, V | 1 |
| Semple, BD | 1 |
| Davidsson, J; Günther, M; Mathiesen, T; Norgren, S; Plantman, S; Risling, M | 1 |
| Deng, H; Jankovic, J; Le, W; Pan, T; Xie, W; Zhao, H; Zhu, W | 1 |
| Chang, E; Jenkins, DD; Singh, I | 1 |
| Abdel Baki, SG; Bergold, PJ; Fenton, AA; Haber, M; Schwab, B | 1 |
| Chang, EY; Newman, R; Singh, I; Sullivan, S; Zhang, J | 1 |
| Balaban, C; Hoffer, B; Hoffer, ME; Slade, MD; Tsao, JW | 1 |
| Hazell, AS; Yi, JH | 1 |
| Griebenow, M; Kroppenstedt, SN; Stover, JF; Thomale, UW; Unterberg, AW | 2 |
| Hazell, AS; Hoover, R; McIntosh, TK; Yi, JH | 1 |
| Contreras, MA; Paintlia, AS; Paintlia, MK; Singh, AK; Singh, I | 1 |
| Chen, G; Hang, C; Hu, Z; Shi, J | 1 |
| Lee, CP; Peterson, PL; Xiong, Y | 1 |
| Chen, BD; Lee, CP; Lin, H; Peterson, PL; Xiong, Y | 1 |
2 review(s) available for acetylcysteine and Acute Brain Injuries
| Article | Year |
|---|---|
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials.
Topics: Acetylcysteine; Brain Injuries; Cerebral Palsy; Child; Choline; Docosahexaenoic Acids; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant; Infant, Newborn; Infant, Premature; Magnesium Sulfate; Pregnancy; Randomized Controlled Trials as Topic; Uridine Monophosphate; Vitamin A; Vitamin D | 2022 |
Free radicals and neonatal encephalopathy: mechanisms of injury, biomarkers, and antioxidant treatment perspectives.
Topics: Acetylcysteine; Allopurinol; Animals; Antioxidants; Asphyxia Neonatorum; Biomarkers; Brain Injuries; Clinical Trials as Topic; DNA; Erythropoietin; Free Radicals; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Malondialdehyde; Melatonin; Nitric Oxide; Oxidative Stress; Prostaglandins; Proteins; Uric Acid | 2020 |
2 trial(s) available for acetylcysteine and Acute Brain Injuries
| Article | Year |
|---|---|
N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI.
Topics: Acetylcysteine; Aldehydes; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Double-Blind Method; Energy Metabolism; Glutathione; Male; Maze Learning; Mitochondria; Neuroprotective Agents; Oxidative Stress; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine | 2014 |
Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled study.
Topics: Acetylcysteine; Adolescent; Adult; Blast Injuries; Brain Injuries; Cognition Disorders; Double-Blind Method; Female; Free Radical Scavengers; Humans; Iraq War, 2003-2011; Male; Memory Disorders; Military Personnel; Neuropsychological Tests; Placebos; Severity of Illness Index; Sleep Initiation and Maintenance Disorders | 2013 |
28 other study(ies) available for acetylcysteine and Acute Brain Injuries
| Article | Year |
|---|---|
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury.
Topics: Animals; Brain Injuries; Cell Survival; Diterpenes; Dose-Response Relationship, Drug; Drug Design; Glutamic Acid; Molecular Structure; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2015 |
N-Acetylcysteine Administration Attenuates Sensorimotor Impairments Following Neonatal Hypoxic-Ischemic Brain Injury in Rats.
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain; Brain Injuries; Hypoxia-Ischemia, Brain; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2022 |
Intestine and brain TLR-4 modulation following N-acetyl-cysteine treatment in NEC rodent model.
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain; Brain Injuries; Disease Models, Animal; Enterocolitis, Necrotizing; Glutathione; Ileum; Intestines; Rats; Rats, Sprague-Dawley; Rodentia; Toll-Like Receptor 4 | 2023 |
Maternal N-acetyl-cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model.
Topics: Acetylcysteine; Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Injuries; Caspase 3; Disease Models, Animal; Enterocolitis, Necrotizing; Female; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Interleukin-6; Nitric Oxide Synthase Type I; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2021 |
Psychosocial impairment following mild blast-induced traumatic brain injury in rats.
Topics: Acetylcysteine; Acrolein; Animals; Blast Injuries; Brain; Brain Concussion; Brain Injuries; Disease Models, Animal; Magnetic Resonance Imaging; Male; Prefrontal Cortex; Psychosocial Functioning; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2021 |
Therapeutic N-Acetyl-Cysteine (Nac) Following Initiation of Maternal Inflammation Attenuates Long-Term Offspring Cerebral Injury, as Evident in Magnetic Resonance Imaging (MRI).
Topics: Acetylcysteine; Animals; Brain; Brain Injuries; Disease Models, Animal; Escherichia coli; Female; Inflammation; Lipopolysaccharides; Male; Neuroprotective Agents; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Random Allocation; Rats, Sprague-Dawley | 2019 |
Neuroprotective effects of N-acetyl cysteine on primary hippocampus neurons against hydrogen peroxide-induced injury are mediated via inhibition of mitogen-activated protein kinases signal transduction and antioxidative action.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Injuries; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Hydrogen Peroxide; MAP Kinase Signaling System; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2018 |
The Protective Effect of Repeated 1MeTIQ Administration on the Lactacystin-Induced Impairment of Dopamine Release and Decline in TH Level in the Rat Brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcysteine; Analysis of Variance; Animals; Brain; Brain Injuries; Cysteine Proteinase Inhibitors; Dopamine; Exploratory Behavior; Functional Laterality; Locomotion; Male; Microdialysis; Neuroprotective Agents; Rats; Rats, Wistar; Tetrahydroisoquinolines | 2018 |
Prophylactic maternal N-acetylcysteine in rats prevents maternal inflammation-induced offspring cerebral injury shown on magnetic resonance imaging.
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain; Brain Injuries; Female; Infectious Disease Transmission, Vertical; Inflammation; Lipopolysaccharides; Magnetic Resonance Imaging; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2013 |
Minocycline plus N-acetylcysteine synergize to modulate inflammation and prevent cognitive and memory deficits in a rat model of mild traumatic brain injury.
Topics: Acetylcysteine; Animals; Avoidance Learning; Brain Injuries; Cognition Disorders; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Inflammation; Memory Disorders; Minocycline; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2013 |
Dendrimer brain uptake and targeted therapy for brain injury in a large animal model of hypothermic circulatory arrest.
Topics: Acetylcysteine; Animals; Biological Transport; Brain; Brain Injuries; Circulatory Arrest, Deep Hypothermia Induced; Dendrimers; Disease Models, Animal; Dogs; Drug Carriers; Male; Microglia; Nanomedicine; Neurons; Rabbits; Treatment Outcome; Valproic Acid | 2014 |
N-acetylcysteine and selenium modulate oxidative stress, antioxidant vitamin and cytokine values in traumatic brain injury-induced rats.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Injuries; Cytokines; Male; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Selenium; Vitamin A | 2014 |
Efficacy of N-acetyl cysteine in traumatic brain injury.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Injuries; Drug Evaluation, Preclinical; Male; Maze Learning; Mice; Mice, Inbred ICR; Rats, Sprague-Dawley; Recognition, Psychology | 2014 |
Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Brain Injuries; Calcium; Caspase 3; Hippocampus; Male; Neurons; Rats, Sprague-Dawley; Selenium | 2014 |
Early preservation of mitochondrial bioenergetics supports both structural and functional recovery after neurotrauma.
Topics: Acetylcysteine; Animals; Brain Injuries; Energy Metabolism; Humans; Mitochondria; Models, Biological; Neuroprotective Agents; Oxidative Stress | 2014 |
Neuroprotective effects of N-acetylcysteine amide on experimental focal penetrating brain injury in rats.
Topics: Acetylcysteine; Animals; Apoptosis; Brain; Brain Injuries; Head Injuries, Penetrating; In Situ Nick-End Labeling; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2015 |
Nurr1 deficiency predisposes to lactacystin-induced dopaminergic neuron injury in vitro and in vivo.
Topics: Acetylcysteine; Analysis of Variance; Animals; Apoptosis; Brain Injuries; Causality; Cell Line, Tumor; DNA-Binding Proteins; Dopamine; Gene Expression Regulation; Humans; Male; Mice; Mice, Knockout; Neuroblastoma; Neurons; Nuclear Receptor Subfamily 4, Group A, Member 2; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Transcription Factors; Transfection; Tyrosine 3-Monooxygenase | 2008 |
Neuroprotective interventions: is it too late?
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain Injuries; Disease Models, Animal; Female; Humans; Hypothermia, Induced; Male; Myelin Sheath; Neuroprotective Agents; Oligodendroglia; Oxidative Stress; Polysaccharides; Pregnancy; Prenatal Exposure Delayed Effects; Research Design; Time Factors | 2009 |
Minocycline synergizes with N-acetylcysteine and improves cognition and memory following traumatic brain injury in rats.
Topics: Acetylcysteine; Animals; Avoidance Learning; Brain Injuries; Cognition; Conditioning, Psychological; Drug Synergism; Interleukin-1beta; Memory; Minocycline; Myelin Sheath; Perception; Rats; Rats, Sprague-Dawley; Task Performance and Analysis; Time Factors | 2010 |
N-acetylcysteine attenuates the maternal and fetal proinflammatory response to intrauterine LPS injection in an animal model for preterm birth and brain injury.
Topics: Acetylcysteine; Animals; Animals, Newborn; Brain; Brain Injuries; Female; Fetal Diseases; Free Radical Scavengers; Mice; Pregnancy; Premature Birth | 2011 |
N-acetylcysteine attenuates early induction of heme oxygenase-1 following traumatic brain injury.
Topics: Acetylcysteine; Animals; Blotting, Western; Brain Injuries; Disease Models, Animal; Enzyme Induction; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Immunohistochemistry; Male; Oxygenases; Percussion; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts; Time Factors | 2005 |
The effect of N-acetylcysteine on posttraumatic changes after controlled cortical impact in rats.
Topics: Acetylcysteine; Animals; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Free Radical Scavengers; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Early, transient increase in complexin I and complexin II in the cerebral cortex following traumatic brain injury is attenuated by N-acetylcysteine.
Topics: Acetylcysteine; Adaptor Proteins, Vesicular Transport; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamic Acid; Hippocampus; Male; Nerve Degeneration; Nerve Tissue Proteins; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; SNARE Proteins; Synaptic Membranes; Synaptic Transmission; Time Factors; Up-Regulation | 2006 |
The antioxidant effect of N-acethylcysteine on experimental contusion in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Brain Edema; Brain Injuries; Disease Models, Animal; Injections, Intraperitoneal; Intracranial Pressure; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2005 |
Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: attenuation by N-acetyl cysteine.
Topics: Acetylcysteine; Acyltransferases; Analysis of Variance; Animals; Brain Injuries; Case-Control Studies; Cells, Cultured; Child, Preschool; Drug Interactions; Female; Fetus; Flow Cytometry; Free Radical Scavengers; Humans; In Vitro Techniques; Infant; Lipopolysaccharides; Neuroglia; Peroxisomal Disorders; Peroxisomes; Pregnancy; Prenatal Exposure Delayed Effects; Reactive Oxygen Species; RNA, Small Interfering; Time Factors; Transfection | 2008 |
Inhibitory effect on cerebral inflammatory response following traumatic brain injury in rats: a potential neuroprotective mechanism of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Apoptosis; Blood-Brain Barrier; Brain Injuries; DNA; Intercellular Adhesion Molecule-1; Interleukin-1beta; Interleukin-6; Male; Neuroprotective Agents; NF-kappa B; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2008 |
Effect of N-acetylcysteine on mitochondrial function following traumatic brain injury in rats.
Topics: Acetylcysteine; Animals; Brain Injuries; Free Radical Scavengers; Glutathione; Male; Mitochondria; Rats; Rats, Sprague-Dawley | 1999 |
Appearance of shortened Bcl-2 and Bax proteins and lack of evidence for apoptosis in rat forebrain after severe experimental traumatic brain injury.
Topics: Acetylcysteine; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain Injuries; Cytochrome c Group; Free Radical Scavengers; Male; Mitochondria; Prosencephalon; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2001 |