acetylcholine-receptor-alpha-subunit-(125-148) has been researched along with Thymus-Neoplasms* in 1 studies
1 other study(ies) available for acetylcholine-receptor-alpha-subunit-(125-148) and Thymus-Neoplasms
Article | Year |
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Antibodies to synthetic peptide (125-148) of the alpha-subunit of human nicotinic acetylcholine receptor in sera from patients with myasthenia gravis.
We measured the amount of antibodies to a synthetic peptide that corresponds to the alpha-subunit residues Lys125-Thr148 of human acetylcholine receptor (AChR) in myasthenic sera. We detected anti-peptide antibodies in 52% (89/171) of the patients with myasthenia gravis (MG), but none in any of the healthy controls. Anti-peptide antibodies should provide a valuable immunologic parameter for the clinical evaluation of MG, but no apparent correlation was observed between the titers of anti-peptide and anti-AChR antibodies. Topics: Autoantibodies; Humans; Myasthenia Gravis; Peptide Fragments; Receptors, Nicotinic; Thymoma; Thymus Neoplasms | 1990 |