Page last updated: 2024-10-15

acetylcarnitine and Peripheral Nerve Injuries

acetylcarnitine has been researched along with Peripheral Nerve Injuries in 11 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Peripheral Nerve Injuries: Injuries to the PERIPHERAL NERVES.

Research Excerpts

ExcerptRelevanceReference
"The main aim of this study was to research new treatments following peripheral nerve injury involving melatonin (Mel), acetyl-l-carnitine (ALCAR), and leptin (Lep) using updated unbiased methods at the stereological and electron microscopic levels."3.85Possible effects of some agents on the injured nerve in obese rats: A stereological and electron microscopic study. ( Altun, G; Altunkaynak, BZ; Geuna, S; Kaplan, S; Muratori, L; Onger, ME; Türkmen, AP, 2017)
"The repair of peripheral nerve injuries is still one of the most challenging tasks and concerns in neurosurgery, plastic and orthopedic surgery."1.40Effect of in situ delivery of acetyl-L-carnitine on peripheral nerve regeneration and functional recovery in transected sciatic nerve in rat. ( Farahpour, MR; Ghayour, SJ, 2014)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's3 (27.27)2.80

Authors

AuthorsStudies
Kencebay Manas, C1
Derin, N1
Arican, RY1
Tanriover, G1
Dilmac, S1
Ozcanli, H1
Wang, J1
Song, J1
Song, G1
Feng, Y1
Pan, J1
Yang, X1
Xin, Z1
Hu, P1
Sun, T1
Liu, K1
Xu, W1
Wang, T1
Wang, S1
Liu, J1
Ruan, Y1
Pourshahidi, S1
Shamshiri, AR1
Derakhshan, S1
Mohammadi, S1
Ghorbani, M1
Catapano, J1
Zhang, J1
Scholl, D1
Chiang, C1
Gordon, T1
Borschel, GH1
Mohammadi, R1
Amini, K1
Onger, ME1
Kaplan, S1
Geuna, S1
Türkmen, AP1
Muratori, L1
Altun, G1
Altunkaynak, BZ1
Farahpour, MR1
Ghayour, SJ1
Kokkalis, ZT1
Soucacos, PN1
Terzis, JK1
Terenghi, G3
Hart, A1
Wiberg, M3
Hart, AM1
Youle, M1
McKay Hart, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome; a Randomized Control Trial.[NCT02141035]Phase 2/Phase 320 participants (Actual)Interventional2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for acetylcarnitine and Peripheral Nerve Injuries

ArticleYear
The Effect of Acetyl-L-Carnitine (ALCAR) on Peripheral Nerve Regeneration in Animal Models: A Systematic Review.
    Neurochemical research, 2023, Volume: 48, Issue:8

    Topics: Acetylcarnitine; Animals; Nerve Regeneration; Peripheral Nerve Injuries; Rats; Sciatic Nerve

2023
The nerve injury and the dying neurons: diagnosis and prevention.
    The Journal of hand surgery, European volume, 2011, Volume: 36, Issue:9

    Topics: Acetylcarnitine; Acetylcysteine; Animals; Axons; Cell Death; Cell Dedifferentiation; Humans; Nerve D

2011

Other Studies

9 other studies available for acetylcarnitine and Peripheral Nerve Injuries

ArticleYear
Comparison of the therapeutic effects of erythropoietin and acetyl-l-carnitine on sciatic nerve injury in rats.
    Neurological research, 2022, Volume: 44, Issue:7

    Topics: Acetylcarnitine; Animals; Caspase 3; Erythropoietin; Nerve Regeneration; Peripheral Nerve Injuries;

2022
Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.
    Andrology, 2022, Volume: 10, Issue:5

    Topics: Acetylcarnitine; Animals; Disease Models, Animal; Erectile Dysfunction; Fibrosis; Humans; Male; Nerv

2022
N-Acetylcysteine Prevents Retrograde Motor Neuron Death after Neonatal Peripheral Nerve Injury.
    Plastic and reconstructive surgery, 2017, Volume: 139, Issue:5

    Topics: Acetylcarnitine; Acetylcysteine; Animals; Cell Death; Cell Survival; Female; Motor Neurons; Peripher

2017
Topically-administered acetyl-L-carnitine increases sciatic nerve regeneration and improves functional recovery after tubulization of transected short nerve gaps.
    Journal of neurosurgical sciences, 2017, Volume: 61, Issue:4

    Topics: Acetylcarnitine; Animals; Male; Nerve Regeneration; Peripheral Nerve Injuries; Rats; Recovery of Fun

2017
Possible effects of some agents on the injured nerve in obese rats: A stereological and electron microscopic study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2017, Volume: 45, Issue:8

    Topics: Acetylcarnitine; Animals; Female; Leptin; Melatonin; Microscopy, Electron; Nerve Regeneration; Obesi

2017
Effect of in situ delivery of acetyl-L-carnitine on peripheral nerve regeneration and functional recovery in transected sciatic nerve in rat.
    International journal of surgery (London, England), 2014, Volume: 12, Issue:12

    Topics: Acetylcarnitine; Animals; Chitosan; Male; Muscle, Skeletal; Nerve Regeneration; Organ Size; Peripher

2014
Effect of acetyl-L-carnitine on axonal sprouting following donor nerve injury distal to an end-to-side neurorrhaphy model.
    Journal of reconstructive microsurgery, 2009, Volume: 25, Issue:8

    Topics: Acetylcarnitine; Animals; Axons; Disease Models, Animal; Electromyography; Male; Motor Endplate; Ner

2009
Systemic acetyl-L-carnitine eliminates sensory neuronal loss after peripheral axotomy: a new clinical approach in the management of peripheral nerve trauma.
    Experimental brain research, 2002, Volume: 145, Issue:2

    Topics: Acetylcarnitine; Animals; Axotomy; Cell Count; Cell Death; DNA Fragmentation; Male; Neurons, Afferen

2002
Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment.
    Neuroscience letters, 2002, Dec-16, Volume: 334, Issue:3

    Topics: Acetylcarnitine; Animals; Axons; Axotomy; Cell Count; Disease Models, Animal; Immunochemistry; Male;

2002