Page last updated: 2024-10-15

acetylcarnitine and Neoplasms

acetylcarnitine has been researched along with Neoplasms in 5 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Ifosfamide and cisplatin cause urinary loss of carnitine, which is a fundamental molecule for energy production in mammalian cells."6.70Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. ( Baldelli, AM; Bisonni, R; Canestrari, F; Catalano, V; De Gaetano, A; Ferraro, B; Giordani, P; Graziano, F; Lai, V; Mencarini, E; Rovidati, S; Silva, R; Testa, E, 2002)
"Fatigue was assessed by the Functional Assessment of Cancer Therapy-Fatigue quality of life questionnaire."6.70Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. ( Baldelli, AM; Bisonni, R; Canestrari, F; Catalano, V; De Gaetano, A; Ferraro, B; Giordani, P; Graziano, F; Lai, V; Mencarini, E; Rovidati, S; Silva, R; Testa, E, 2002)
"To evaluate the effect of the anti-cancer drug carboplatin on plasma concentrations and urinary excretion of L-carnitine (LC) and its main ester, acetyl-L-carnitine (ALC), in cancer patients."2.73Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment. ( Bisonni, R; Calvani, M; D'Iddio, S; Graziano, F; Lippe, P; Mancinelli, A, 2007)
"Ifosfamide and cisplatin cause urinary loss of carnitine, which is a fundamental molecule for energy production in mammalian cells."2.70Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. ( Baldelli, AM; Bisonni, R; Canestrari, F; Catalano, V; De Gaetano, A; Ferraro, B; Giordani, P; Graziano, F; Lai, V; Mencarini, E; Rovidati, S; Silva, R; Testa, E, 2002)
"Fatigue was assessed by the Functional Assessment of Cancer Therapy-Fatigue quality of life questionnaire."2.70Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. ( Baldelli, AM; Bisonni, R; Canestrari, F; Catalano, V; De Gaetano, A; Ferraro, B; Giordani, P; Graziano, F; Lai, V; Mencarini, E; Rovidati, S; Silva, R; Testa, E, 2002)
"CIPN is an important consequence of cancer treatment because of its potential impact on physical functioning and quality of life."2.44Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy. ( Abbott, L; Aschenbrenner, J; Collins, M; Hart, C; Visovsky, C, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zahednezhad, F1
Shahbazi Mojarrad, J1
Zakeri-Milani, P1
Baradaran, B1
Mahmoudian, M1
Sarfraz, M1
Valizadeh, H1
van Dam, DG1
Beijers, AJ1
Vreugdenhil, G1
Mancinelli, A1
D'Iddio, S1
Bisonni, R2
Graziano, F2
Lippe, P1
Calvani, M1
Visovsky, C1
Collins, M1
Abbott, L1
Aschenbrenner, J1
Hart, C1
Catalano, V1
Silva, R1
Rovidati, S1
Mencarini, E1
Ferraro, B1
Canestrari, F1
Baldelli, AM1
De Gaetano, A1
Giordani, P1
Testa, E1
Lai, V1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534]29 participants (Actual)Observational2015-09-30Completed
A Randomised, Double Blinded Cross-over Study Comparing the Efficacy of L-carnitine Versus Placebo in the Treatment of Fatigue in Multiple Sclerosis[NCT01149525]Phase 359 participants (Actual)Interventional2010-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for acetylcarnitine and Neoplasms

ArticleYear
Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy.
    Clinical journal of oncology nursing, 2007, Volume: 11, Issue:6

    Topics: Acetylcarnitine; Acupuncture Therapy; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplas

2007

Trials

2 trials available for acetylcarnitine and Neoplasms

ArticleYear
Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:1

    Topics: Acetylcarnitine; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area U

2007
Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients.
    British journal of cancer, 2002, Jun-17, Volume: 86, Issue:12

    Topics: Acetylcarnitine; Aged; Antineoplastic Agents; Carnitine; Cisplatin; Fatigue; Female; Humans; Ifosfam

2002

Other Studies

2 other studies available for acetylcarnitine and Neoplasms

ArticleYear
Surface modification with cholesteryl acetyl carnitine, a novel cationic agent, elevates cancer cell uptake of the PEGylated liposomes.
    International journal of pharmaceutics, 2021, Nov-20, Volume: 609

    Topics: Acetylcarnitine; Cations; Liposomes; Molecular Docking Simulation; Neoplasms; Particle Size; Polyeth

2021
Acetyl-L-carnitine undervalued in the treatment of chemotherapy-induced peripheral neuropathy?
    Acta oncologica (Stockholm, Sweden), 2016, Volume: 55, Issue:12

    Topics: Acetylcarnitine; Antineoplastic Combined Chemotherapy Protocols; Humans; Neoplasms; Peripheral Nervo

2016