Page last updated: 2024-10-15

acetylcarnitine and Myocardial Ischemia

acetylcarnitine has been researched along with Myocardial Ischemia in 4 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Treatment with acetylcarnitine (AcCN) increases the activity of cytochrome oxidase in the aged heart."1.33Reversal of mitochondrial defects before ischemia protects the aged heart. ( He, D; Hoppel, CL; Lesnefsky, EJ; Moghaddas, S, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schroeder, MA1
Atherton, HJ1
Ball, DR1
Cole, MA1
Heather, LC1
Griffin, JL1
Clarke, K1
Radda, GK1
Tyler, DJ1
Lesnefsky, EJ1
He, D1
Moghaddas, S1
Hoppel, CL1
Simkhovich, BZ1
Hale, SL1
Ovize, M1
Przyklenk, K1
Kloner, RA1
Löster, H1
Keller, T1
Grommisch, J1
Gründer, W1

Other Studies

4 other studies available for acetylcarnitine and Myocardial Ischemia

ArticleYear
Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2009, Volume: 23, Issue:8

    Topics: Acetylcarnitine; Animals; Carbon Isotopes; Citric Acid; Citric Acid Cycle; Energy Metabolism; Glutam

2009
Reversal of mitochondrial defects before ischemia protects the aged heart.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:9

    Topics: Acetylcarnitine; Aging; Animals; Disease Models, Animal; Heart; L-Lactate Dehydrogenase; Male; Mitoc

2006
Ischemic preconditioning and long-chain acyl carnitine in the canine heart.
    Coronary artery disease, 1993, Volume: 4, Issue:4

    Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Coronary Circulation; Dogs; Myocardial

1993
Effects of L-carnitine and its acetyl and propionyl esters on ATP and PCr levels of isolated rat hearts perfused without fatty acids and investigated by means of 31P-NMR spectroscopy.
    Molecular and cellular biochemistry, 1999, Volume: 200, Issue:1-2

    Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Energy Metabolism; Female; Heart; In Vi

1999