acetylcarnitine has been researched along with Muscle Disorders in 4 studies
Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effect of starvation or ACTH injection on the urinary level and profile of L-carnitine and its derivatives was studied in four healthy adult men or in a normal child and two patients with myopathy, respectively." | 3.66 | Urinary profile of L-carnitine and its derivatives in starved normal persons and ACTH injected patients with myopathy. ( Kinoshita, M; Suzuki, M; Tokuyama, K, 1983) |
| "Rhabdomyolysis is common in very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) and other metabolic myopathies, but its pathogenic basis is poorly understood." | 1.43 | Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency. ( de Sain-van der Velden, M; Diekman, EF; Houten, SM; Jeneson, JA; Nievelstein, RA; Schmitz, JP; Takken, T; Van der Pol, WL; van Riel, NA; Visser, G; Wardrop, M, 2016) |
| " Female Wistar Hanover rats were dosed daily for 12 days (oral gavage) with either vehicle (control, 0." | 1.38 | Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents. ( Constantin-Teodosiu, D; Davies, WJ; Glaves, PD; Greenhaff, PL; Mallinson, JE; Martin, EA; Sidaway, JE; Westwood, FR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diekman, EF | 1 |
| Visser, G | 1 |
| Schmitz, JP | 1 |
| Nievelstein, RA | 1 |
| de Sain-van der Velden, M | 1 |
| Wardrop, M | 1 |
| Van der Pol, WL | 1 |
| Houten, SM | 1 |
| van Riel, NA | 1 |
| Takken, T | 1 |
| Jeneson, JA | 1 |
| Mallinson, JE | 1 |
| Constantin-Teodosiu, D | 1 |
| Glaves, PD | 1 |
| Martin, EA | 1 |
| Davies, WJ | 1 |
| Westwood, FR | 1 |
| Sidaway, JE | 1 |
| Greenhaff, PL | 1 |
| Suzuki, M | 1 |
| Tokuyama, K | 1 |
| Kinoshita, M | 1 |
| Rettinger, A | 1 |
| Gempel, K | 1 |
| Hofmann, S | 1 |
| Gerbitz, KD | 1 |
| Bauer, MF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Nutritional Ketosis and Exercise in Glycogen Storage Disease Type IIIa[NCT03011203] | 6 participants (Actual) | Interventional | 2017-02-10 | Completed | |||
| Acute Nutritional Ketosis in VLCAD Deficiency: Testing the Metabolic Base for Therapeutic Use[NCT03531554] | 5 participants (Actual) | Interventional | 2016-04-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for acetylcarnitine and Muscle Disorders
| Article | Year |
|---|---|
Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase, Long-Chain; Adenosine Triphosphate; Adolescent; Adult; Case | 2016 |
Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase, Long-Chain; Adenosine Triphosphate; Adolescent; Adult; Case | 2016 |
Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase, Long-Chain; Adenosine Triphosphate; Adolescent; Adult; Case | 2016 |
Altered Energetics of Exercise Explain Risk of Rhabdomyolysis in Very Long-Chain Acyl-CoA Dehydrogenase Deficiency.
Topics: Acetylcarnitine; Acyl-CoA Dehydrogenase, Long-Chain; Adenosine Triphosphate; Adolescent; Adult; Case | 2016 |
Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents.
Topics: Acetylcarnitine; Animals; Body Weight; Carbohydrate Metabolism; Cathepsin L; Cytoprotection; Dichlor | 2012 |
Urinary profile of L-carnitine and its derivatives in starved normal persons and ACTH injected patients with myopathy.
Topics: Acetylcarnitine; Adrenocorticotropic Hormone; Adult; Carnitine; Child, Preschool; Female; Humans; Hy | 1983 |
Tandem mass spectrometric assay for the determination of carnitine palmitoyltransferase II activity in muscle tissue.
Topics: Acetylcarnitine; Carnitine; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Humans; | 2002 |