Page last updated: 2024-10-15

acetylcarnitine and Migraine Disorders

acetylcarnitine has been researched along with Migraine Disorders in 1 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hagen, K1
Brenner, E1
Linde, M1
Gravdahl, GB1
Tronvik, EA1
Engstrøm, M1
Sonnewald, U1
Helde, G1
Stovner, LJ1
Sand, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Acetyl-L-carnitine in Migraine - a Randomized, Double-blind Placebo Controlled Study[NCT01695317]Phase 472 participants (Actual)Interventional2013-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Days With Migraine and Side Effects

Secondary measures will be: Days with migraine; days with headache; hours with headache; headache intensity (0-3 scale) on days with headache; doses of analgesics; doses of triptans; days with sick leave; number of responders (≥ 50% decrease in migraine days compared with baseline); incidence of side effects recorded openly. (NCT01695317)
Timeframe: Last 4 weeks

InterventionHeadache hours per 4 weeks (Mean)
Acetyl-L-carnitine36.4
Sugar Pills37.0

Headache Days

The number of days per 4 weeks with moderate or severe headache lasting ≥ 4 hours or if treated with the patient's usual headache medication (usually a triptan) as the primary endpoint. (NCT01695317)
Timeframe: last 4 weeks

InterventionHeadache days per 4 weeks (Mean)
Acetyl-L-carnitine5.1
Sugar Pills5.2

Trials

1 trial available for acetylcarnitine and Migraine Disorders

ArticleYear
Acetyl-l-carnitine versus placebo for migraine prophylaxis: A randomized, triple-blind, crossover study.
    Cephalalgia : an international journal of headache, 2015, Volume: 35, Issue:11

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Cross-Over Studies; Female; Humans; Male; Middle Aged; Mig

2015