acetylcarnitine has been researched along with Lesion of Sciatic Nerve in 8 studies
Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "ALCAR completely prevented mechanical hyperalgesia and provoked in the nerve a c-Jun increment only." | 1.36 | The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain. ( Bartolini, A; Di Cesare Mannelli, L; Ghelardini, C; Pacini, A; Toscano, A, 2010) |
| "Peripheral neuropathies are widespread disorders induced by autoimmune diseases, drug or toxin exposure, infections, metabolic insults or trauma." | 1.34 | Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy. ( Bartolini, A; Calvani, M; Di Cesare Mannelli, L; Ghelardini, C; Mosconi, L; Nicolai, R; Pacini, A; Vivoli, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kencebay Manas, C | 1 |
| Derin, N | 1 |
| Arican, RY | 1 |
| Tanriover, G | 1 |
| Dilmac, S | 1 |
| Ozcanli, H | 1 |
| Parisi, S | 1 |
| Ditto, MC | 1 |
| Borrelli, R | 1 |
| Fusaro, E | 1 |
| Mohammad-Bagher, G | 1 |
| Arash, A | 1 |
| Morteza, BR | 1 |
| Naser, MS | 1 |
| Ali, M | 1 |
| Di Cesare Mannelli, L | 2 |
| Ghelardini, C | 2 |
| Toscano, A | 1 |
| Pacini, A | 2 |
| Bartolini, A | 2 |
| Karsidag, S | 2 |
| Akcal, A | 1 |
| Sahin, S | 1 |
| Kabukcuoglu, F | 1 |
| Ugurlu, K | 1 |
| Namazi, H | 1 |
| Calvani, M | 1 |
| Nicolai, R | 1 |
| Mosconi, L | 1 |
| Vivoli, E | 1 |
| Kotil, K | 1 |
| Kirali, M | 1 |
| Eras, M | 1 |
| Bilge, T | 1 |
| Uzun, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome; a Randomized Control Trial.[NCT02141035] | Phase 2/Phase 3 | 20 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for acetylcarnitine and Lesion of Sciatic Nerve
| Article | Year |
|---|---|
Comparison of the therapeutic effects of erythropoietin and acetyl-l-carnitine on sciatic nerve injury in rats.
Topics: Acetylcarnitine; Animals; Caspase 3; Erythropoietin; Nerve Regeneration; Peripheral Nerve Injuries; | 2022 |
Efficacy of a fixed combination of palmitoylethanolamide and acetyl-l-carnitine (PEA+ALC FC) in the treatment of neuropathies secondary to rheumatic diseases.
Topics: Acetylcarnitine; Aged; Amides; Analgesics, Non-Narcotic; Carpal Tunnel Syndrome; Drug Administration | 2021 |
Synergistic Effects of Acetyl-l-Carnitine and Adipose-Derived Stromal Cells on Improving Regenerative Capacity of Acellular Nerve Allograft in Sciatic Nerve Defect.
Topics: Acellular Dermis; Acetylcarnitine; Adipose Tissue; Allografts; Animals; Male; Nerve Regeneration; Ra | 2019 |
The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain.
Topics: Acetylcarnitine; Animals; Disease Models, Animal; Enzyme Activation; Functional Laterality; Hyperalg | 2010 |
Neurophysiological and morphological responses to treatment with acetyl-L-carnitine in a sciatic nerve injury model: preliminary data.
Topics: Acetylcarnitine; Action Potentials; Animals; Disease Models, Animal; Electromyography; Male; Neural | 2012 |
Re: Karsidag S, Akcal A, Sahin S, et al. Neurophysiological and morphological responses to treatment with acetyl-L-carnitine in a sciatic nerve injury model: preliminary data. J Hand Surg Eur. 2012, 37: 529-536.
Topics: Acetylcarnitine; Animals; Male; Sciatic Nerve; Sciatic Neuropathy; Vitamin B Complex | 2012 |
Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy.
Topics: Acetylcarnitine; Animals; Apoptosis; Blotting, Western; Caspase 3; Cytochromes c; Cytosol; DNA Fragm | 2007 |
Neuroprotective effects of acetyl-L-carnithine in experimental chronic compression neuropathy. A prospective, randomized and placebo-control trials.
Topics: Acetylcarnitine; Animals; Axons; Chronic Disease; Decompression, Surgical; Disease Models, Animal; F | 2007 |