Page last updated: 2024-10-15

acetylcarnitine and Depressive Disorder

acetylcarnitine has been researched along with Depressive Disorder in 11 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
"Sixty-four anhedonic alcohol dependent patients with minor or absent withdrawal symptoms were randomized: 23 received ALC at a dosage of 3g/day, 21 received ALC at a dosage of 1g/day, and 20 were given placebo."2.76Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects. ( Andreoli, S; D'Iddio, S; Di Nicola, M; Fanella, F; Iannoni, E; Martinotti, G; Ortolani, I; Pozzi, G; Prof, LJ; Reina, D; Tedeschi, D, 2011)
"Minimal hepatic encephalopathy (MHE) represents a common complication present in well-compensated cirrhotic patients that impairs patients' daily functioning and health-related quality of life (HRQL)."2.76Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy. ( Bella, R; Gargante, MP; Giordano, M; Malaguarnera, G; Malaguarnera, M; Mistretta, A; Motta, M; Pennisi, G; Rampello, L; Vacante, M, 2011)
" Furthermore, combination therapy provides less adverse effects."1.42[Optimization of the efficacy and safety of antidepressant therapy in patients of a geriatric psychiatric unit]. ( Gavrilova, SI; Kalyn, YB; Kornilov, VV; Safarova, TP; Sheshenin, VS; Shipilova, ES; Yakovleva, OB, 2015)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's1 (9.09)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suzuki, H1
Hibino, H1
Inoue, Y1
Mikami, K1
Post, RM1
Wang, W1
Lu, Y1
Xue, Z1
Li, C1
Wang, C1
Zhao, X1
Zhang, J1
Wei, X1
Chen, X1
Cui, W1
Wang, Q1
Zhou, W1
Gavrilova, SI1
Kalyn, YB1
Safarova, TP1
Yakovleva, OB1
Sheshenin, VS1
Kornilov, VV1
Shipilova, ES1
Martinotti, G1
Andreoli, S1
Reina, D1
Di Nicola, M1
Ortolani, I1
Tedeschi, D1
Fanella, F1
Pozzi, G1
Iannoni, E1
D'Iddio, S1
Prof, LJ1
Malaguarnera, M1
Bella, R2
Vacante, M1
Giordano, M1
Malaguarnera, G1
Gargante, MP1
Motta, M1
Mistretta, A1
Rampello, L1
Pennisi, G2
Levine, J1
Panchalingam, K1
McClure, RJ1
Gershon, S1
Pettegrew, JW1
Biondi, R1
Raffaele, R1
Garzya, G1
Corallo, D1
Fiore, A1
Lecciso, G1
Petrelli, G1
Zotti, C1
Tempesta, E1
Casella, L1
Pirrongelli, C1
Janiri, L1
Calvani, M1
Ancona, L1

Trials

5 trials available for acetylcarnitine and Depressive Disorder

ArticleYear
Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jun-01, Volume: 35, Issue:4

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Alcoholism; Depressive Disorder; Diagnosis, Dual (Psychiat

2011
Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy.
    Scandinavian journal of gastroenterology, 2011, Volume: 46, Issue:6

    Topics: Acetylcarnitine; Adult; Aged; Anxiety Disorders; Depressive Disorder; Double-Blind Method; Female; H

2011
Effect of acetyl-L-carnitine on geriatric patients suffering from dysthymic disorders.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:6

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Depressive Disorder; Humans; Middle Aged; Psychiatric Stat

1990
Evaluation of the effects of L-acetylcarnitine on senile patients suffering from depression.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:2

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Carnitine; Clinical Trials as Topic; Dementia; Depressive

1990
L-acetylcarnitine in depressed elderly subjects. A cross-over study vs placebo.
    Drugs under experimental and clinical research, 1987, Volume: 13, Issue:7

    Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Depressive Disorder; Female; Humans; Mal

1987

Other Studies

6 other studies available for acetylcarnitine and Depressive Disorder

ArticleYear
The benefits of the concomitant use of antidepressants and acetyl-l-carnitine in the treatment of moderate depression.
    Asian journal of psychiatry, 2019, Volume: 41

    Topics: Acetylcarnitine; Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Drug Therapy, Combin

2019
Myriad of implications of acetyl-l-carnitine deficits in depression.
    Proceedings of the National Academy of Sciences of the United States of America, 2018, 08-21, Volume: 115, Issue:34

    Topics: Acetylcarnitine; Carnitine; Depression; Depressive Disorder; Humans

2018
Rapid-acting antidepressant-like effects of acetyl-l-carnitine mediated by PI3K/AKT/BDNF/VGF signaling pathway in mice.
    Neuroscience, 2015, Jan-29, Volume: 285

    Topics: Acetylcarnitine; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Chromones; Depre

2015
[Optimization of the efficacy and safety of antidepressant therapy in patients of a geriatric psychiatric unit].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:6

    Topics: Acetamides; Acetylcarnitine; Aged; Antidepressive Agents; Apathy; Cyclohexanols; Depressive Disorder

2015
Effects of acetyl-L-carnitine and myo-inositol on high-energy phosphate and membrane phospholipid metabolism in zebra fish: a 31P-NMR-spectroscopy study.
    Neurochemical research, 2003, Volume: 28, Issue:5

    Topics: Acetylcarnitine; Animals; Depressive Disorder; Humans; Inositol; Magnetic Resonance Spectroscopy; Me

2003
Acetyl-L-carnitine.
    Alternative medicine review : a journal of clinical therapeutic, 1999, Volume: 4, Issue:6

    Topics: Acetylcarnitine; Alzheimer Disease; Animals; Depressive Disorder; Diabetic Neuropathies; HIV Infecti

1999