acetylcarnitine has been researched along with Dementia in 23 studies
Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute effects of intravenously administered L-acetylcarnitine (LAC) were evaluated with single-photon emission computed tomography (SPECT) and 99mTc-hexamethylpropyleneamine oxime in 30 demented patients (21 with a clinical diagnosis of Alzheimer's dementia and 9 with mixed-type dementia)." | 7.67 | Single-photon emission computed tomography studies with 99mTc-hexamethylpropyleneamine oxime in dementia: effects of acute administration of L-acetylcarnitine. ( Battistin, L; Borsato, N; Calvani, M; Da Col, C; Dam, M; Ferlin, G; Perlotto, N; Pizzolato, G; Saitta, B, 1989) |
| "Adults of both genders without dementia consumed a nutriceutical formulation ("NF," consisting of folic acid, B12, Vitamin E, S-adenosylmethionine, N-acetyl cysteine and Acetyl-L-carnitine), previously shown to improve cognitive performance in Alzheimer's disease, or placebo." | 5.14 | A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia. ( Chan, A; Kotyla, E; Lepore, A; Remington, R; Shea, TB; Zemianek, J, 2010) |
| "The trials were identified from a search of the Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 8 January 2003 using the terms acetyl-l-carnitine, l-carnitine acetyl ester, acetylcarnitine." | 4.82 | Acetyl-L-carnitine for dementia. ( Hudson, S; Tabet, N, 2003) |
| "The acute effects of intravenously administered L-acetylcarnitine (LAC) were evaluated with single-photon emission computed tomography (SPECT) and 99mTc-hexamethylpropyleneamine oxime in 30 demented patients (21 with a clinical diagnosis of Alzheimer's dementia and 9 with mixed-type dementia)." | 3.67 | Single-photon emission computed tomography studies with 99mTc-hexamethylpropyleneamine oxime in dementia: effects of acute administration of L-acetylcarnitine. ( Battistin, L; Borsato, N; Calvani, M; Da Col, C; Dam, M; Ferlin, G; Perlotto, N; Pizzolato, G; Saitta, B, 1989) |
| "Dementia is a common mental health problem affecting 5% of those over 65." | 2.42 | Acetyl-L-carnitine for dementia. ( Hudson, S; Tabet, N, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 15 (65.22) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Pennisi, M | 1 |
| Lanza, G | 1 |
| Cantone, M | 1 |
| D'Amico, E | 1 |
| Fisicaro, F | 1 |
| Puglisi, V | 1 |
| Vinciguerra, L | 1 |
| Bella, R | 1 |
| Vicari, E | 1 |
| Malaguarnera, G | 1 |
| Ferrari, F | 1 |
| Gorini, A | 1 |
| Villa, RF | 1 |
| Chan, A | 1 |
| Remington, R | 1 |
| Kotyla, E | 1 |
| Lepore, A | 1 |
| Zemianek, J | 1 |
| Shea, TB | 1 |
| Hudson, S | 1 |
| Tabet, N | 1 |
| Acierno, G | 1 |
| Ganesan, R | 1 |
| Standish, T | 1 |
| Molloy, DW | 1 |
| Darzins, P | 1 |
| Orange, JB | 1 |
| Kidd, PM | 1 |
| Lino, A | 1 |
| Boccia, MM | 1 |
| Rusconi, AC | 1 |
| Bellomonte, L | 1 |
| Cocuroccia, B | 1 |
| Herrmann, WM | 1 |
| Stephan, K | 1 |
| Recchia, G | 2 |
| Zerbini, O | 1 |
| Fabbri, L | 1 |
| Neri, M | 1 |
| Cortelloni, C | 1 |
| De Vreese, L | 1 |
| Roncolato, M | 1 |
| Meneghetti, M | 1 |
| Bamfi, F | 1 |
| Girelli, M | 1 |
| Cipolli, C | 1 |
| Chiari, G | 1 |
| Genazzani, E | 1 |
| Goety, CG | 1 |
| Tanner, CM | 1 |
| Cohen, JA | 1 |
| Thelen, JA | 1 |
| Carroll, VS | 1 |
| Klawans, HL | 1 |
| Fariello, RG | 1 |
| Passeri, M | 2 |
| Cucinotta, D | 2 |
| Bonati, PA | 2 |
| Iannuccelli, M | 3 |
| Parnetti, L | 1 |
| Senin, U | 1 |
| Garzya, G | 1 |
| Corallo, D | 1 |
| Fiore, A | 1 |
| Lecciso, G | 1 |
| Petrelli, G | 1 |
| Zotti, C | 1 |
| Sinforiani, E | 1 |
| Mauri, M | 1 |
| Costa, A | 1 |
| Merlo, P | 1 |
| Bono, G | 1 |
| Nappi, G | 1 |
| Battistin, L | 1 |
| Pizzolato, G | 1 |
| Dam, M | 1 |
| Da Col, C | 1 |
| Perlotto, N | 1 |
| Saitta, B | 1 |
| Borsato, N | 1 |
| Calvani, M | 1 |
| Ferlin, G | 1 |
| Ciotti, G | 1 |
| Nolfe, G | 1 |
| Davoli, D | 1 |
| Marchesi, M | 1 |
| Bertolotti, S | 1 |
| Bellesia, G | 1 |
| Pioli, G | 1 |
| Iori, E | 1 |
5 reviews available for acetylcarnitine and Dementia
| Article | Year |
|---|---|
Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update.
Topics: Acetylcarnitine; Brain; Cognition; Cognition Disorders; Dementia; Humans; Liver; Nootropic Agents; T | 2020 |
Acetyl-L-carnitine for dementia.
Topics: Acetylcarnitine; Aged; Alzheimer Disease; Dementia; Humans; Nootropic Agents; Randomized Controlled | 2003 |
New treatments for dementia. Myth, magic, and science.
Topics: Acetylcarnitine; Adult; Aged; Aged, 80 and over; Attitude to Death; Attitude to Health; Canada; Cult | 1994 |
A review of nutrients and botanicals in the integrative management of cognitive dysfunction.
Topics: Acetylcarnitine; Cognition Disorders; Complementary Therapies; Dementia; Ginkgo biloba; Humans; Noot | 1999 |
[Pharmacologic treatment of senile mental deterioration].
Topics: Acetylcarnitine; Cytidine Diphosphate Choline; Dementia; Humans; Neuropeptides; Parasympathomimetics | 1987 |
14 trials available for acetylcarnitine and Dementia
| Article | Year |
|---|---|
A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia.
Topics: Acetylcarnitine; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Dementia; Dietary Suppleme | 2010 |
[The use of 1-acetylcarnitine in (presenile and senile) Alzheimer's disease. Preliminary results].
Topics: Acetylcarnitine; Aged; Alzheimer Disease; Carnitine; Clinical Trials as Topic; Dementia; Double-Blin | 1983 |
[Psycho-functional changes in attention and learning under the action of L-acetylcarnitine in 17 young subjects. A pilot study of its use in mental deterioration].
Topics: Acetylcarnitine; Adult; Age Factors; Analysis of Variance; Attention; Dementia; Female; Humans; Lear | 1992 |
Efficacy and clinical relevance of cognition enhancers.
Topics: Acetylcarnitine; Clinical Trials as Topic; Cognition; Cognition Disorders; Dementia; Humans; Nimodip | 1991 |
[Aging of the population: the 2d demographic revolution].
Topics: Acetylcarnitine; Aged; Aged, 80 and over; Carnitine; Clinical Trials as Topic; Dementia; Demography; | 1990 |
[Clinical development of a drug for brain aging. Current limitations and future prospects].
Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Dementia; Diagnosis, Differential; Human | 1990 |
[Methodology of a clinical controlled study of L-acetylcarnitine].
Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Dementia; Humans; Middle Aged; Multicent | 1990 |
[Center monitoring and management of data bases].
Topics: Acetylcarnitine; Carnitine; Clinical Trials as Topic; Database Management Systems; Dementia; Humans; | 1990 |
[Effects of L-acetylcarnitine on mental deterioration in the aged: initial results].
Topics: Acetylcarnitine; Aged; Analysis of Variance; Behavior; Carnitine; Clinical Trials as Topic; Cognitio | 1990 |
[A controlled clinical study on the efficacy of L-acetylcarnitine in the treatment of mild-to-moderate mental deterioration in the aged. Conclusions].
Topics: Acetylcarnitine; Aged; Carnitine; Clinical Trials as Topic; Dementia; Humans; Middle Aged; Multicent | 1990 |
L-acetyl-carnitine in Huntington's disease: double-blind placebo controlled crossover study of drug effects on movement disorder and dementia.
Topics: Acetylcarnitine; Adult; Aged; Carnitine; Dementia; Double-Blind Method; Female; Humans; Huntington D | 1990 |
Acetyl-L-carnitine in the treatment of mildly demented elderly patients.
Topics: Acetylcarnitine; Aged; Carnitine; Cognition; Dementia; Double-Blind Method; Female; Humans; Male; Ra | 1990 |
Evaluation of the effects of L-acetylcarnitine on senile patients suffering from depression.
Topics: Acetylcarnitine; Aged; Aged, 80 and over; Carnitine; Clinical Trials as Topic; Dementia; Depressive | 1990 |
Mental impairment in aging: selection of patients, methods of evaluation and therapeutic possibilities of acetyl-L-carnitine.
Topics: Acetylcarnitine; Aged; Aged, 80 and over; Analysis of Variance; Carnitine; Dementia; Female; Humans; | 1988 |
4 other studies available for acetylcarnitine and Dementia
| Article | Year |
|---|---|
Functional proteomics of synaptic plasma membrane ATP-ases of rat hippocampus: effect of l-acetylcarnitine and relationships with Dementia and Depression pathophysiology.
Topics: Acetylcarnitine; Acetylcholinesterase; Adenosine Triphosphatases; Animals; Dementia; Depression; Fem | 2015 |
[Methodological premises of statistical analysis of the data].
Topics: Acetylcarnitine; Age Factors; Aged; Analysis of Variance; Carnitine; Data Interpretation, Statistica | 1990 |
Neuropsychological changes in demented patients treated with acetyl-L-carnitine.
Topics: Acetylcarnitine; Aged; Brain Ischemia; Carnitine; Dementia; Female; Humans; Male; Middle Aged; Pirac | 1990 |
Single-photon emission computed tomography studies with 99mTc-hexamethylpropyleneamine oxime in dementia: effects of acute administration of L-acetylcarnitine.
Topics: Acetylcarnitine; Aged; Alzheimer Disease; Carnitine; Dementia; Female; Humans; Injections, Intraveno | 1989 |