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acetylcarnitine and Cognition Disorders

acetylcarnitine has been researched along with Cognition Disorders in 15 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the putative neurotherapeutic effects of the mitochondrial cofactors, L-carnitine, acetyl-L-carnitine, and alpha-lipoic acid; and to provide a rationale for investigating their efficacy in the treatment of neurocognitive deficits associated with mood disorders."8.84Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? ( Chow, CS; Kennedy, SH; Konarski, JZ; McIntyre, RS; Soczynska, JK; Woldeyohannes, HO, 2008)
"Mood disorders are associated with decrements in cognitive function, which are insufficiently treated with contemporary pharmacotherapies."6.44Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? ( Chow, CS; Kennedy, SH; Konarski, JZ; McIntyre, RS; Soczynska, JK; Woldeyohannes, HO, 2008)
"To evaluate the putative neurotherapeutic effects of the mitochondrial cofactors, L-carnitine, acetyl-L-carnitine, and alpha-lipoic acid; and to provide a rationale for investigating their efficacy in the treatment of neurocognitive deficits associated with mood disorders."4.84Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? ( Chow, CS; Kennedy, SH; Konarski, JZ; McIntyre, RS; Soczynska, JK; Woldeyohannes, HO, 2008)
"ALC slows the progression of Alzheimer's disease in younger subjects, and the use of the trilinear approach to estimate the average rate of change may prove valuable in pharmacological trials."2.69Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach. ( Bravi, D; Brooks, JO; Carta, A; Yesavage, JA, 1998)
"People with Down syndrome are vulnerable to developing dementia at an earlier age than the general population."2.52Pharmacological interventions for cognitive decline in people with Down syndrome. ( Hanratty, J; Livingstone, N; Macdonald, G; McShane, R, 2015)
"Mood disorders are associated with decrements in cognitive function, which are insufficiently treated with contemporary pharmacotherapies."2.44Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? ( Chow, CS; Kennedy, SH; Konarski, JZ; McIntyre, RS; Soczynska, JK; Woldeyohannes, HO, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's5 (33.33)18.2507
2000's2 (13.33)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Pennisi, M1
Lanza, G1
Cantone, M1
D'Amico, E1
Fisicaro, F1
Puglisi, V1
Vinciguerra, L1
Bella, R1
Vicari, E1
Malaguarnera, G1
Bigford, GE1
Del Rossi, G1
Mehrotra, A1
Kanwal, A1
Banerjee, SK1
Sandhir, R1
Snigdha, S1
de Rivera, C1
Milgram, NW1
Cotman, CW1
Livingstone, N1
Hanratty, J1
McShane, R1
Macdonald, G1
Suchy, J1
Chan, A1
Shea, TB1
Glade, MJ1
Malaguarnera, M1
Soczynska, JK1
Kennedy, SH1
Chow, CS1
Woldeyohannes, HO1
Konarski, JZ1
McIntyre, RS1
Pascale, A1
Milano, S1
Corsico, N1
Lucchi, L1
Battaini, F1
Martelli, EA1
Trabucchi, M1
Govoni, S1
Brooks, JO1
Yesavage, JA1
Carta, A1
Bravi, D1
Kidd, PM1
Herrmann, WM1
Stephan, K1
Tempesta, E1
Troncon, R1
Janiri, L1
Colusso, L1
Riscica, P1
Saraceni, G1
Gesmundo, E1
Calvani, M1
Benedetti, N1
Pola, P1
Bonavita, E1

Reviews

7 reviews available for acetylcarnitine and Cognition Disorders

ArticleYear
Acetyl-L-Carnitine in Dementia and Other Cognitive Disorders: A Critical Update.
    Nutrients, 2020, May-12, Volume: 12, Issue:5

    Topics: Acetylcarnitine; Brain; Cognition; Cognition Disorders; Dementia; Humans; Liver; Nootropic Agents; T

2020
Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders.
    Advances in nutrition (Bethesda, Md.), 2014, Volume: 5, Issue:4

    Topics: Acetylcarnitine; Alzheimer Disease; Brain; Brain Injuries; Cinnamates; Cognition Disorders; Curcumin

2014
Pharmacological interventions for cognitive decline in people with Down syndrome.
    The Cochrane database of systematic reviews, 2015, Oct-29, Issue:10

    Topics: Acetylcarnitine; Adult; Antioxidants; Cognition; Cognition Disorders; Donepezil; Down Syndrome; Huma

2015
Oxidative stress and cognitive longevity.
    Nutrition (Burbank, Los Angeles County, Calif.), 2010, Volume: 26, Issue:6

    Topics: Acetylcarnitine; Aging; Animals; Central Nervous System; Cognition; Cognition Disorders; Humans; Lon

2010
Carnitine derivatives: clinical usefulness.
    Current opinion in gastroenterology, 2012, Volume: 28, Issue:2

    Topics: Acetylcarnitine; Cardiotonic Agents; Cardiovascular Diseases; Carnitine; Cognition Disorders; Depres

2012
Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders?
    Expert opinion on investigational drugs, 2008, Volume: 17, Issue:6

    Topics: Acetylcarnitine; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carnitine; Cl

2008
A review of nutrients and botanicals in the integrative management of cognitive dysfunction.
    Alternative medicine review : a journal of clinical therapeutic, 1999, Volume: 4, Issue:3

    Topics: Acetylcarnitine; Cognition Disorders; Complementary Therapies; Dementia; Ginkgo biloba; Humans; Noot

1999

Trials

4 trials available for acetylcarnitine and Cognition Disorders

ArticleYear
Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach.
    International psychogeriatrics, 1998, Volume: 10, Issue:2

    Topics: Acetylcarnitine; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Disea

1998
Efficacy and clinical relevance of cognition enhancers.
    Alzheimer disease and associated disorders, 1991, Volume: 5 Suppl 1

    Topics: Acetylcarnitine; Clinical Trials as Topic; Cognition; Cognition Disorders; Dementia; Humans; Nimodip

1991
Role of acetyl-L-carnitine in the treatment of cognitive deficit in chronic alcoholism.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:1-2

    Topics: Acetylcarnitine; Adult; Alcoholism; Carnitine; Clinical Trials as Topic; Cognition Disorders; Double

1990
Study of the efficacy and tolerability of L-acetylcarnitine therapy in the senile brain.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:9

    Topics: Acetylcarnitine; Aged; Aged, 80 and over; Anxiety Disorders; Carnitine; Cognition Disorders; Depress

1986

Other Studies

4 other studies available for acetylcarnitine and Cognition Disorders

ArticleYear
Mitochondrial modulators in experimental Huntington's disease: reversal of mitochondrial dysfunctions and cognitive deficits.
    Neurobiology of aging, 2015, Volume: 36, Issue:6

    Topics: Acetylcarnitine; Animals; Cognition Disorders; Drug Therapy, Combination; Female; Huntington Disease

2015
Effect of mitochondrial cofactors and antioxidants supplementation on cognition in the aged canine.
    Neurobiology of aging, 2016, Volume: 37

    Topics: Acetylcarnitine; Aging; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Coenzymes

2016
Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance.
    Nutrition research (New York, N.Y.), 2009, Volume: 29, Issue:1

    Topics: Acetylcarnitine; Alzheimer Disease; Animals; Antioxidants; Apolipoproteins E; Cognition Disorders; D

2009
Protein kinase C activation and anti-amnesic effect of acetyl-L-carnitine: in vitro and in vivo studies.
    European journal of pharmacology, 1994, Nov-14, Volume: 265, Issue:1-2

    Topics: Acetylcarnitine; Amnesia; Animals; Cerebral Cortex; Cognition Disorders; Dose-Response Relationship,

1994