Page last updated: 2024-10-15

acetylcarnitine and Bipolar Disorder

acetylcarnitine has been researched along with Bipolar Disorder in 5 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"A 47-year-old man suffering from a bipolar disorder and intermittent myoglobinuria presented with acute rhabdomyolysis with renal failure after starting therapy with valproic acid."7.71Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. ( Glocker, FX; Jaksch, M; Ketelsen, UP; Kottlors, M; Lücking, CH; Weiner, S, 2001)
" Three groups of patients were studied: (A) epileptic under phenytoin monotherapy (n = 31); (B) with bipolar disorder under valproic acid treatment (n = 28); (C) elderly (n = 41)."5.22Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia. ( Fagiolino, P; González, R; Guevara, N; Maldonado, C; Queijo, C; Vázquez, M, 2016)
"A 47-year-old man suffering from a bipolar disorder and intermittent myoglobinuria presented with acute rhabdomyolysis with renal failure after starting therapy with valproic acid."3.71Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. ( Glocker, FX; Jaksch, M; Ketelsen, UP; Kottlors, M; Lücking, CH; Weiner, S, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Maiti, R1
Mishra, A1
Mishra, BR1
Jena, M1
Brennan, BP1
Jensen, JE1
Hudson, JI1
Coit, CE1
Beaulieu, A1
Pope, HG1
Renshaw, PF1
Cohen, BM1
Maldonado, C1
Guevara, N1
Queijo, C1
González, R1
Fagiolino, P1
Vázquez, M1
Goodison, G1
Overeem, K1
de Monte, V1
Siskind, D1
Kottlors, M1
Jaksch, M1
Ketelsen, UP1
Weiner, S1
Glocker, FX1
Lücking, CH1

Reviews

1 review available for acetylcarnitine and Bipolar Disorder

ArticleYear
Comparative efficacy of mitochondrial agents for bipolar disorder during depressive episodes: a network meta-analysis using frequentist and Bayesian approaches.
    Psychopharmacology, 2021, Volume: 238, Issue:12

    Topics: Acetylcarnitine; Bayes Theorem; Bipolar Disorder; Humans; Network Meta-Analysis; Treatment Outcome

2021

Trials

2 trials available for acetylcarnitine and Bipolar Disorder

ArticleYear
A placebo-controlled trial of acetyl-L-carnitine and α-lipoic acid in the treatment of bipolar depression.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:5

    Topics: Acetylcarnitine; Adult; Antidepressive Agents; Bipolar Disorder; Brain; Chi-Square Distribution; Dru

2013
Carnitine and/or Acetylcarnitine Deficiency as a Cause of Higher Levels of Ammonia.
    BioMed research international, 2016, Volume: 2016

    Topics: Acetylcarnitine; Adolescent; Adult; Aged; Aged, 80 and over; Ammonia; Bipolar Disorder; Carnitine; E

2016

Other Studies

2 other studies available for acetylcarnitine and Bipolar Disorder

ArticleYear
Mania associated with self-prescribed acetyl-l-carnitine in a man with bipolar I disorder.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2017, Volume: 25, Issue:1

    Topics: Acetylcarnitine; Adult; Bipolar Disorder; Dietary Supplements; Humans; Male; Psychoses, Substance-In

2017
Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency.
    Neuromuscular disorders : NMD, 2001, Volume: 11, Issue:8

    Topics: Acetylcarnitine; Acute Disease; Antimanic Agents; Bipolar Disorder; Carnitine O-Palmitoyltransferase

2001