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acetylcarnitine and Alloxan Diabetes

acetylcarnitine has been researched along with Alloxan Diabetes in 28 studies

Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.

Research Excerpts

ExcerptRelevanceReference
" Animals with 4 weeks of hyperglycemia and reduced NCV treated with an aldose reductase inhibitor (sorbinil) or a short-chain acyl-carnitine (acetyl-L-carnitine [ALC]) daily for 16 weeks showed an improvement in NCV."3.69The effects of acetyl-L-carnitine and sorbinil on peripheral nerve structure, chemistry, and function in experimental diabetes. ( Carver, J; Korthals, JK; Lowitt, S; Malone, JI; Miranda, C; Salem, AF, 1996)
"Flurbiprofen treatment of ND rats replicated many of the biochemical and physiological abnormalities of EDN, i."1.31Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. ( Greene, DA; Larkin, D; Li, F; Marinescu, V; Pop-Busui, R; Stevens, MJ; Sullivan, K; Van Huysen, C, 2002)
"Sorbinil treatment was associated with normalized sciatic nerve sorbitol and myo-inositol; ALC treatment did not reduce the elevated sorbitol levels, but sciatic nerve myo-inositol content was no different from nondiabetic levels."1.29Acetyl-L-carnitine corrects the altered peripheral nerve function of experimental diabetes. ( Benford, S; Korthals, J; Lowitt, S; Malone, JI; Salem, AF, 1995)
"Treatment with sorbinil was associated with normalization of the tissue sorbitol (0."1.28Altered neuroexcitability in experimental diabetic neuropathy: effect of acetyl-L-carnitine. ( Corsico, N; Lowitt, S; Malone, JI; Orfalian, Z, 1992)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's15 (53.57)18.2507
2000's8 (28.57)29.6817
2010's2 (7.14)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Yao, H1
Wang, Y1
Zhang, X1
Li, P1
Shang, L1
Chen, X1
Zeng, J1
Wang, CH1
Wang, SS1
Ko, WJ1
Chen, YS1
Chang, CY1
Chang, RW1
Chang, KC3
Tseng, CD1
Lu, SC1
Liang, JT1
Wu, MS1
Tsai, MS1
Hsu, KL1
Pop-Busui, R1
Marinescu, V1
Van Huysen, C1
Li, F1
Sullivan, K1
Greene, DA2
Larkin, D1
Stevens, MJ2
PEARSON, DJ1
TUBBS, PK1
Defani, MA4
Zanoni, JN2
Natali, MR2
Bazotte, RB2
de Miranda-Neto, MH1
Fregonesi, CE3
Molinari, SL1
Alves, AM2
de Miranda Neto, MH3
Pereira, A1
Alves, EP1
Stabille, SR1
Evangelista, CC1
Dos Santos, CA1
Cresto, JC1
Fabiano de Bruno, LE1
Cao, GF1
Pastorale, CF1
Confalonieri, N1
del Carmen Camberos, M1
Basabe, JC1
Ohsawa, M1
Miyata, S1
Carlsson, A1
Kamei, J1
Cotter, MA1
Cameron, NE1
Keegan, A1
Dines, KC1
Lowitt, S4
Malone, JI4
Salem, AF2
Korthals, J1
Benford, S1
Ido, Y1
McHowat, J1
Arrigoni-Martelli, E1
Orfalian, Z3
Kilo, C1
Corr, PB1
Williamson, JR1
Salem, A1
Kozak, WM1
Marzo, A1
Corsico, N3
Cardace, G1
Morabito, E2
Serafini, S1
Martelli, EA1
Lattimer, SA1
Feldman, EL1
Helton, ED1
Millington, DS1
Sima, AA1
Miranda, C1
Korthals, JK1
Carver, J1
Abdel-aleem, S1
Karim, AM1
Zarouk, WA1
Taylor, DA1
el-Awady, MK1
Lowe, JE1
Nakamura, J1
Koh, N1
Sakakibara, F1
Hamada, Y1
Hara, T1
Sasaki, H1
Chaya, S1
Komori, T1
Nakashima, E1
Naruse, K1
Kato, K1
Takeuchi, N1
Kasuya, Y1
Hotta, N1
Kano, M1
Kawakami, T1
Hori, H1
Hashimoto, Y1
Tao, Y1
Ishikawa, Y1
Takenaka, T1
Lo Giudice, P1
Careddu, A1
Magni, G1
Quagliata, T1
Pacifici, L2
Carminati, P1
Gorio, A3
Di Giulio, AM2
Tenconi, B1
Donadoni, L1
Germani, E1
Bertelli, A2
Mantegazza, P2
Maccari, F2
Ramacci, MT3
Ferraris, L1
Bellucci, A1
Piovesan, P1
Hekimian, G1
Feuvray, D1

Other Studies

28 other studies available for acetylcarnitine and Alloxan Diabetes

ArticleYear
Targeting peroxisomal fatty acid oxidation improves hepatic steatosis and insulin resistance in obese mice.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:2

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Fatty Acids; Fatty Liv

2023
Acetyl-l-carnitine and oxfenicine on cardiac pumping mechanics in streptozotocin-induced diabetes in male Wistar rats.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acetylcarnitine; Animals; Antioxidants; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glycine;

2013
Effects of acetyl-L-carnitine and oxfenicine on aorta stiffness in diabetic rats.
    European journal of clinical investigation, 2010, Volume: 40, Issue:11

    Topics: Acetylcarnitine; Analysis of Variance; Animals; Aorta; Carnitine O-Palmitoyltransferase; Diabetes Me

2010
Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration.
    Diabetes, 2002, Volume: 51, Issue:8

    Topics: Acetylcarnitine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase

2002
ACETYL-CARNITINE IN HEART AND LIVER.
    Nature, 1964, Apr-04, Volume: 202

    Topics: Acetates; Acetylcarnitine; Acyltransferases; Animals; Coenzyme A; Diabetes Mellitus, Experimental; G

1964
Effect of acetyl-L-carnitine on VIP-ergic neurons in the jejunum submucous plexus of diabetic rats.
    Arquivos de neuro-psiquiatria, 2003, Volume: 61, Issue:4

    Topics: Acetylcarnitine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Die

2003
Morphoquantitative aspects of nitrergic myoenteric neurons from the stomach of diabetic rats supplemented with acetyl-L-carnitine.
    Anatomia, histologia, embryologia, 2005, Volume: 34, Issue:2

    Topics: Acetylcarnitine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Supplements; Male;

2005
Morphometric and quantitative evaluation of the NADH-diaphorase positive myenteric neurons of the jejunum of streptozotocin-diabetic rats supplemented with acetyl-L-carnitine.
    Anatomia, histologia, embryologia, 2005, Volume: 34, Issue:3

    Topics: Acetylcarnitine; Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Histoc

2005
Morphoquantitative aspects of NADH-diaphorase myenteric neurons in the ileum of diabetic rats treated with acetyl-L-carnitine.
    Anatomia, histologia, embryologia, 2006, Volume: 35, Issue:1

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Dihydrolipoamide Dehydrogenase; Histocyto

2006
The association of acetyl-l-carnitine and nicotinamide remits the experimental diabetes in mice by multiple low-dose streptozotocin.
    Pancreas, 2006, Volume: 33, Issue:4

    Topics: Acetylcarnitine; Animals; Blood Glucose; Body Weight; Cells, Cultured; Diabetes Mellitus, Experiment

2006
Preventive effect of acetyl-L-carnitine on the thermal hypoalgesia in streptozotocin-induced diabetic mice.
    European journal of pharmacology, 2008, Jul-07, Volume: 588, Issue:2-3

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Mice; Mice,

2008
Effects of acetyl- and proprionyl-L-carnitine on peripheral nerve function and vascular supply in experimental diabetes.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:9

    Topics: Acetylcarnitine; Action Potentials; Animals; Blood Flow Velocity; Blood Glucose; Body Weight; Carnit

1995
Acetyl-L-carnitine corrects the altered peripheral nerve function of experimental diabetes.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:5

    Topics: Acetylcarnitine; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies

1995
Neural dysfunction and metabolic imbalances in diabetic rats. Prevention by acetyl-L-carnitine.
    Diabetes, 1994, Volume: 43, Issue:12

    Topics: Acetylcarnitine; Animals; Ca(2+) Mg(2+)-ATPase; Carnitine; Diabetes Mellitus, Experimental; Diabetic

1994
Acetyl-L-carnitine corrects electroretinographic deficits in experimental diabetes.
    Diabetes, 1993, Volume: 42, Issue:8

    Topics: Acetylcarnitine; Aldehyde Reductase; Analysis of Variance; Animals; Diabetes Mellitus, Experimental;

1993
Effect of acetyl-L-carnitine treatment on the levels of levocarnitine and its derivatives in streptozotocin-diabetic rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:3

    Topics: Acetylcarnitine; Animals; Behavior, Animal; Blood Glucose; Carnitine; Diabetes Mellitus, Experimenta

1993
Acetyl-L-carnitine effect on nerve conduction velocity in streptozotocin-diabetic rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:3

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Male; Neural Conduction; Rats

1993
Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dose-Response Rela

1996
The effects of acetyl-L-carnitine and sorbinil on peripheral nerve structure, chemistry, and function in experimental diabetes.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: Acetylcarnitine; Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies

1996
Reduced effects of L-carnitine on glucose and fatty acid metabolism in myocytes isolated from diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1997, Volume: 29, Issue:9

    Topics: Acetyl Coenzyme A; Acetylcarnitine; Animals; Carbon Radioisotopes; Carnitine; Citric Acid Cycle; Dia

1997
Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:3

    Topics: Acetylcarnitine; Aldehyde Reductase; Animals; Body Weight; Carnitine; Diabetes Mellitus, Experimenta

1998
Effects of ALCAR on the fast axoplasmic transport in cultured sensory neurons of streptozotocin-induced diabetic rats.
    Neuroscience research, 1999, Volume: 33, Issue:3

    Topics: Acetylcarnitine; Afferent Pathways; Animals; Axonal Transport; Blood Glucose; Body Weight; Cells, Cu

1999
Autonomic neuropathy in streptozotocin diabetic rats: effect of acetyl-L-carnitine.
    Diabetes research and clinical practice, 2002, Volume: 56, Issue:3

    Topics: Acetylcarnitine; Animals; Autonomic Nervous System Diseases; Blood Glucose; Body Weight; Diabetes Me

2002
Peptide alterations in autonomic diabetic neuropathy prevented by acetyl-L-carnitine.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:5-6

    Topics: Acetylcarnitine; Animals; Autonomic Nervous System Diseases; Diabetes Mellitus, Experimental; Diabet

1992
Acetyl-L-carnitine prevents substance P loss in the sciatic nerve and lumbar spinal cord of diabetic animals.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:5-6

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Lumbar Vertebrae;

1992
Counteraction on experimentally induced diabetic neuropathy by levocarnitine acetyl.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:5-6

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Motor Activi

1992
Altered neuroexcitability in experimental diabetic neuropathy: effect of acetyl-L-carnitine.
    International journal of clinical pharmacology research, 1992, Volume: 12, Issue:5-6

    Topics: Acetylcarnitine; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Imidazoles; Imidaz

1992
Reduction of ischemia-induced acyl carnitine accumulation by TDGA and its influence on lactate dehydrogenase release in diabetic rat hearts.
    Diabetes, 1986, Volume: 35, Issue:8

    Topics: Acetylcarnitine; Adenosine Triphosphate; Animals; Carnitine; Coronary Disease; Diabetes Mellitus, Ex

1986