acetylcarnitine has been researched along with Allodynia in 6 studies
Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Evidence from animal models of chemotherapy-induced painful peripheral neuropathy produced by the taxane agent, paclitaxel, and the platinum-complex agent, oxaliplatin, indicate that they produce neuropathy via a common mechanism-a toxic effect on the mitochondria in primary afferent sensory neurons." | 5.38 | Mitotoxicity and bortezomib-induced chronic painful peripheral neuropathy. ( Bennett, GJ; Xiao, WH; Zheng, H, 2012) |
| "L-acetylcarnitine treatment enhanced mGlu2/3 receptor protein levels in the dorsal region of the spinal cord." | 1.46 | Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain. ( Battaglia, G; Bernabucci, M; Bruno, V; Cannella, M; Gradini, R; Imbriglio, T; Mascio, G; Nicoletti, F; Notartomaso, S; Scarselli, P; Zappulla, C, 2017) |
| " Evidence from animal models of chemotherapy-induced painful peripheral neuropathy produced by the taxane agent, paclitaxel, and the platinum-complex agent, oxaliplatin, indicate that they produce neuropathy via a common mechanism-a toxic effect on the mitochondria in primary afferent sensory neurons." | 1.38 | Mitotoxicity and bortezomib-induced chronic painful peripheral neuropathy. ( Bennett, GJ; Xiao, WH; Zheng, H, 2012) |
| "ALCAR completely prevented mechanical hyperalgesia and provoked in the nerve a c-Jun increment only." | 1.36 | The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain. ( Bartolini, A; Di Cesare Mannelli, L; Ghelardini, C; Pacini, A; Toscano, A, 2010) |
| "Peripheral neuropathies are widespread disorders induced by autoimmune diseases, drug or toxin exposure, infections, metabolic insults or trauma." | 1.34 | Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy. ( Bartolini, A; Calvani, M; Di Cesare Mannelli, L; Ghelardini, C; Mosconi, L; Nicolai, R; Pacini, A; Vivoli, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lucarini, E | 1 |
| Micheli, L | 1 |
| Toti, A | 1 |
| Ciampi, C | 1 |
| Margiotta, F | 1 |
| Di Cesare Mannelli, L | 3 |
| Ghelardini, C | 3 |
| Ardizzone, A | 1 |
| Fusco, R | 1 |
| Casili, G | 1 |
| Lanza, M | 1 |
| Impellizzeri, D | 1 |
| Esposito, E | 1 |
| Cuzzocrea, S | 1 |
| Notartomaso, S | 1 |
| Mascio, G | 1 |
| Bernabucci, M | 1 |
| Zappulla, C | 1 |
| Scarselli, P | 1 |
| Cannella, M | 1 |
| Imbriglio, T | 1 |
| Gradini, R | 1 |
| Battaglia, G | 1 |
| Bruno, V | 1 |
| Nicoletti, F | 1 |
| Toscano, A | 1 |
| Pacini, A | 2 |
| Bartolini, A | 2 |
| Zheng, H | 1 |
| Xiao, WH | 1 |
| Bennett, GJ | 1 |
| Calvani, M | 1 |
| Nicolai, R | 1 |
| Mosconi, L | 1 |
| Vivoli, E | 1 |
6 other studies available for acetylcarnitine and Allodynia
| Article | Year |
|---|---|
Anti-Hyperalgesic Efficacy of Acetyl L-Carnitine (ALCAR) Against Visceral Pain Induced by Colitis: Involvement of Glia in the Enteric and Central Nervous System.
Topics: Acetylcarnitine; Animals; Central Nervous System; Colitis; Humans; Hyperalgesia; Neuroglia; Rats; Vi | 2023 |
Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain.
Topics: Acetylcarnitine; Amides; Animals; Carrageenan; Cell Count; Cyclooxygenase 2; Disease Models, Animal; | 2021 |
Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain.
Topics: Acetylcarnitine; Amitriptyline; Analgesics; Animals; Chronic Disease; Disease Models, Animal; Epigen | 2017 |
The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain.
Topics: Acetylcarnitine; Animals; Disease Models, Animal; Enzyme Activation; Functional Laterality; Hyperalg | 2010 |
Mitotoxicity and bortezomib-induced chronic painful peripheral neuropathy.
Topics: Acetylcarnitine; Activating Transcription Factor 3; Adenosine Triphosphate; Analysis of Variance; An | 2012 |
Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy.
Topics: Acetylcarnitine; Animals; Apoptosis; Blotting, Western; Caspase 3; Cytochromes c; Cytosol; DNA Fragm | 2007 |