Page last updated: 2024-10-22

acetyl-dl-leucine and Gangliosidoses, GM2

acetyl-dl-leucine has been researched along with Gangliosidoses, GM2 in 1 studies

acetylleucine: used for treating vestibular-related imbalance and vertigo

Gangliosidoses, GM2: A group of recessively inherited diseases characterized by the intralysosomal accumulation of G(M2) GANGLIOSIDE in the neuronal cells. Subtypes include mutations of enzymes in the BETA-N-ACETYLHEXOSAMINIDASES system or G(M2) ACTIVATOR PROTEIN leading to disruption of normal degradation of GANGLIOSIDES, a subclass of ACIDIC GLYCOSPHINGOLIPIDS.

Research Excerpts

ExcerptRelevanceReference
" NALL was safe and well tolerated, contributing to an overall favorable risk:benefit profile."3.30Efficacy and Safety of N-Acetyl-l-Leucine in Children and Adults With GM2 Gangliosidoses. ( Bremova-Ertl, T; Claassen, J; Gascon-Bayari, J; Goldschagg, N; Hahn, A; Hassan, A; Hennig, A; Jones, S; Kay, R; Lau, H; Martakis, K; Perlman, S; Schneider, S; Sharma, R, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Martakis, K3
Claassen, J3
Gascon-Bayari, J3
Goldschagg, N3
Hahn, A3
Hassan, A3
Hennig, A3
Jones, S3
Kay, R3
Lau, H3
Perlman, S3
Sharma, R3
Schneider, S3
Bremova-Ertl, T3

Trials

1 trial available for acetyl-dl-leucine and Gangliosidoses, GM2

ArticleYear
Efficacy and Safety of N-Acetyl-l-Leucine in Children and Adults With GM2 Gangliosidoses.
    Neurology, 2023, 03-07, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Ataxia; Child; Female; Gangliosidoses, GM2; Humans; Male; Middle Aged; Quality of

2023
Efficacy and Safety of N-Acetyl-l-Leucine in Children and Adults With GM2 Gangliosidoses.
    Neurology, 2023, 03-07, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Ataxia; Child; Female; Gangliosidoses, GM2; Humans; Male; Middle Aged; Quality of

2023
Efficacy and Safety of N-Acetyl-l-Leucine in Children and Adults With GM2 Gangliosidoses.
    Neurology, 2023, 03-07, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Ataxia; Child; Female; Gangliosidoses, GM2; Humans; Male; Middle Aged; Quality of

2023
Efficacy and Safety of N-Acetyl-l-Leucine in Children and Adults With GM2 Gangliosidoses.
    Neurology, 2023, 03-07, Volume: 100, Issue:10

    Topics: Adolescent; Adult; Ataxia; Child; Female; Gangliosidoses, GM2; Humans; Male; Middle Aged; Quality of

2023