acetyl-dl-leucine has been researched along with Adiadochokinesis in 8 studies
acetylleucine: used for treating vestibular-related imbalance and vertigo
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy, safety, and tolerability of the modified essential amino acid acetyl-DL-leucine in treating patients who have cerebellar ataxia." | 9.41 | Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial. ( Adrion, C; Boesch, S; Doss, S; Feil, K; Giordano, I; Hengel, H; Jacobi, H; Klockgether, T; Klopstock, T; Mansmann, U; Nachbauer, W; Naumann, I; Schöls, L; Steiner, KM; Stendel, C; Strupp, M; Timmann, D, 2021) |
| "To investigate the efficacy, safety, and tolerability of the modified essential amino acid acetyl-DL-leucine in treating patients who have cerebellar ataxia." | 5.41 | Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial. ( Adrion, C; Boesch, S; Doss, S; Feil, K; Giordano, I; Hengel, H; Jacobi, H; Klockgether, T; Klopstock, T; Mansmann, U; Nachbauer, W; Naumann, I; Schöls, L; Steiner, KM; Stendel, C; Strupp, M; Timmann, D, 2021) |
| " Although the positive effects of N-acetyl-DL-leucine on cerebellar ataxia have been reported previously, there is little evidence of N-acetyl-DL-leucine's effects in patients with AT." | 4.31 | The Effect of N-Acetyl-DL-Leucine on Neurological Symptoms in a Patient with Ataxia-Telangiectasia: a Case Study. ( Beyraghi-Tousi, M; Gumpricht, E; Mirzadeh, M; Saberi-Karimian, M; Sahebkar, A, 2023) |
| "Cerebellar ataxia is a frequent and often disabling syndrome severely impairing motor functioning and quality of life." | 2.61 | Aminopyridines and Acetyl-DL-leucine: New Therapies in Cerebellar Disorders. ( Kalla, R; Strupp, M, 2019) |
| "Pharmacological treatment of cerebellar ataxias and cerebellar nystagmus still remains difficult." | 2.53 | Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus. ( Bremova, T; Feil, K; Muth, C; Schniepp, R; Strupp, M; Teufel, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feil, K | 5 |
| Adrion, C | 2 |
| Boesch, S | 1 |
| Doss, S | 1 |
| Giordano, I | 2 |
| Hengel, H | 2 |
| Jacobi, H | 2 |
| Klockgether, T | 2 |
| Klopstock, T | 3 |
| Nachbauer, W | 2 |
| Schöls, L | 2 |
| Steiner, KM | 1 |
| Stendel, C | 2 |
| Timmann, D | 1 |
| Naumann, I | 2 |
| Mansmann, U | 2 |
| Strupp, M | 6 |
| Saberi-Karimian, M | 3 |
| Beyraghi-Tousi, M | 1 |
| Mirzadeh, M | 1 |
| Gumpricht, E | 1 |
| Sahebkar, A | 3 |
| Becker-Bense, S | 1 |
| Kaiser, L | 1 |
| Becker, R | 1 |
| Muth, C | 3 |
| Albert, NL | 1 |
| Unterrainer, M | 1 |
| Bartenstein, P | 1 |
| Dieterich, M | 1 |
| Houra, M | 2 |
| Jamialahmadi, T | 2 |
| Sarvghadi, P | 2 |
| Nikbaf, M | 2 |
| Akhlaghi, S | 2 |
| Kalla, R | 1 |
| Teufel, J | 3 |
| Habs, M | 1 |
| Feuerecker, R | 1 |
| van de Warrenburg, BP | 1 |
| Bremova, T | 1 |
| Schniepp, R | 1 |
| Bösch, S | 1 |
| Claassen, J | 1 |
| Uslar, E | 1 |
| van de Warrenburg, B | 1 |
| Berger, I | 1 |
| Bayer, O | 1 |
| Müller, HH | 1 |
2 reviews available for acetyl-dl-leucine and Adiadochokinesis
| Article | Year |
|---|---|
Aminopyridines and Acetyl-DL-leucine: New Therapies in Cerebellar Disorders.
Topics: Aminopyridines; Animals; Cerebellar Ataxia; Cerebellar Diseases; Humans; Leucine | 2019 |
Update on the Pharmacotherapy of Cerebellar Ataxia and Nystagmus.
Topics: 4-Aminopyridine; Cerebellar Ataxia; Chlorzoxazone; Drug Therapy; Humans; Leucine; Muscle Relaxants, | 2016 |
2 trials available for acetyl-dl-leucine and Adiadochokinesis
| Article | Year |
|---|---|
Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial.
Topics: Administration, Oral; Adult; Aged; Cerebellar Ataxia; Cross-Over Studies; Double-Blind Method; Drug | 2021 |
Effects of acetyl-DL-leucine on cerebellar ataxia (ALCAT trial): study protocol for a multicenter, multinational, randomized, double-blind, placebo-controlled, crossover phase III trial.
Topics: Adult; Cerebellar Ataxia; Cross-Over Studies; Double-Blind Method; Humans; Leucine; Psychiatric Stat | 2017 |
4 other studies available for acetyl-dl-leucine and Adiadochokinesis
| Article | Year |
|---|---|
The Effect of N-Acetyl-DL-Leucine on Neurological Symptoms in a Patient with Ataxia-Telangiectasia: a Case Study.
Topics: Ataxia Telangiectasia; Cerebellar Ataxia; Child; Female; Humans; Leucine; Quality of Life | 2023 |
Acetyl-DL-leucine in cerebellar ataxia ([
Topics: Ataxia; Cerebellar Ataxia; Fluorodeoxyglucose F18; Humans; Quality of Life; Retrospective Studies | 2023 |
The Effects of N-Acetyl-L-Leucine on the Improvement of Symptoms in a Patient with Multiple Sulfatase Deficiency.
Topics: Ataxia; Cerebellar Ataxia; Child; Female; Humans; Interleukin-6; Multiple Sulfatase Deficiency Disea | 2023 |
The Effects of N-Acetyl-L-Leucine on the Improvement of Symptoms in a Patient with Multiple Sulfatase Deficiency.
Topics: Ataxia; Cerebellar Ataxia; Child; Female; Humans; Interleukin-6; Multiple Sulfatase Deficiency Disea | 2023 |
The Effects of N-Acetyl-L-Leucine on the Improvement of Symptoms in a Patient with Multiple Sulfatase Deficiency.
Topics: Ataxia; Cerebellar Ataxia; Child; Female; Humans; Interleukin-6; Multiple Sulfatase Deficiency Disea | 2023 |
The Effects of N-Acetyl-L-Leucine on the Improvement of Symptoms in a Patient with Multiple Sulfatase Deficiency.
Topics: Ataxia; Cerebellar Ataxia; Child; Female; Humans; Interleukin-6; Multiple Sulfatase Deficiency Disea | 2023 |
Effects of acetyl-DL-leucine in patients with cerebellar ataxia: a case series.
Topics: Adolescent; Adult; Aged; Cerebellar Ataxia; Disability Evaluation; Female; Humans; Leucine; Male; Mi | 2013 |