Page last updated: 2024-08-17

acetyl coenzyme a and Neoplasms

acetyl coenzyme a has been researched along with Neoplasms in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.85)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (1.92)	29.6817
2010's	34 (65.38)	24.3611
2020's	15 (28.85)	2.80

Authors

Authors	Studies
Chua, KF; Li, TM; Tasselli, L; Zheng, W	1
Al-Hilfi, A; Walker, KD	1
Basak, D; Basak, S; Bhowmik, D; Chakraborty, P; Chatterjee, S; Chowdhury, S; Deka, A; Gautam, A; Ghosh, P; Kar, A; Mehrotra, S; Mukhopadhyay, A; Paul, S; Sarkar, D; Sarkar, I	1
Kundu, TK; Senapati, P; Singh, S	1
He, W; Li, Q; Li, X	1
Guertin, DA; Wellen, KE	1
Asiaban, JN; Bilotta, EM; Bishop, TR; Erb, MA; Garnar-Wortzel, L; Ott, CJ; Ramos, AR; Rock, CO; Subramanian, C; Zhang, Y	1
Das, S; Deshmukh, RS; Kumari, R	1
Alifano, M; Coquerel, A; Fournel, L; Icard, P; Lincet, H; Wu, Z	1
Glauben, R; Siegmund, B; Weidinger, C; Yerinde, C	1
Gao, J; Gao, Y; Guo, L; Zhang, Y; Zhu, Z	1
Ma, Q; Reiter, RJ; Sharma, R	1
Israël, M; Schwartz, L	1
Klement, RJ; Koebrunner, PS	1
Du, W; Sheng, Z	1
Anderson, G	1
Reiter, RJ; Rosales-Corral, S; Sharma, R	1
Corbet, C; Feron, O	2
Xie, C; Zhang, S	1
Algire, M; Bromberg, KD; Buchanan, FG; Chiang, GG; Choudhary, C; Cole, PA; de Vries, P; Digiammarino, EL; Edalji, RP; Faivre, E; Ferguson, D; Frey, R; Hansen, TM; Hessler, P; Jakob, CG; Karukurichi, K; Kesicki, E; Lai, A; Lam, LT; Langston, JW; Lasko, LM; Manaves, V; Marmorstein, R; Martin, RL; McElligott, D; Michaelides, MR; Montgomery, D; Qiu, W; Risi, RM; Rosenberg, SH; Shaw, B; Sun, C; Torrent, M; Uziel, T; Van Drie, JH; Weinert, BT	1
Stacpoole, PW	1
Guo, YR; Hawke, D; He, J; Lee, JH; Li, XJ; Liu, K; Liu, R; Lu, Z; Lyu, J; Qian, X; Tan, L; Tao, YJ; Wang, Y; Xia, Y; Xing, D; Yang, P; Yin, Z; Zheng, Y	1
Chen, R; Garcia, JA; Nagati, J; Xu, M	1
Abdel-Aziz, W; Abdel-Latif, HM; Aboonq, MS; Ahmed, NS; Almaramhy, HH; Ayat, M; Baghdadi, H; El Sayed, SM; El-Sawy, SA; Elshazley, M; Ibrahim, W; Mahmoud, AA	1
Bai, C; Chu, Q; Li, B; Liu, M; Qiu, L; Ruan, Y; Wang, Y; Yang, C	1
Eil, R; Finkel, T; Ha, NH; Huang, J; Kishton, RJ; Klebanoff, CA; Kruhlak, MJ; Lee, PH; Liu, X; Locasale, JW; Palmer, DC; Patel, SJ; Restifo, NP; Roychoudhuri, R; Shin, M; Sukumar, M; Vodnala, SK; Yamamoto, TN; Yu, Z	1
Alghanem, AF; Alhumeed, N; Aljasir, MA; Ball, C; Chadwick, AE; Cross, M; Djouhri, L; Ramsey, S; Sathish, JG; Sethu, S; Stebbings, R; Thaventhiran, T; Webb, SD; Wong, W; Yeang, HXA	1
Bose, S; Locasale, JW; Ramesh, V	1
Cao, Y; Gao, M; He, Y; Liu, S; Tang, H; Tao, Y	1
Fujibayashi, Y; Furukawa, T; Saga, T; Yoshii, Y	1
Barnhart, TE; Bendlin, BB; Christian, BT; Clarkson, BD; Hillmer, AT; Lao, PJ; Li, M; Mitchell, HA; Pehar, M; Peng, Y; Puglielli, L; Sandor, M	1
Cho, EJ; Choi, J; Jang, H; Kim, TW; Lee, JE; Lee, JH; Lee, SM; Youn, HD	1
Carrer, A; Wellen, KE	1
Cai, L; Comerford, SA; Du, X; Fu, A; Hammer, RE; Horton, JD; Huang, Z; Manning, HC; McKnight, SL; Tantawy, MN; Tu, BP; Walters, H; Wang, Y; Witkiewicz, AK	1
Denu, JM; Fan, J; Feldman, JL; Krautkramer, KA	1
Jaworski, DM; Moffett, JR; Namboodiri, AM	1
Iwamoto, T; Matsufuji, S; Migita, T; Murai, N; Murakami, Y; Tajima, A	1
Lisanti, MP; Martinez-Outschoorn, UE; Peiris-Pagés, M; Pestell, RG; Sotgia, F	1
Chen, S; He, D; Sang, N; Tan, X; Yin, C	1
Corbet, C; Feron, O; Martherus, R; Pinto, A; Polet, F; Santiago de Jesus, JP	1
Gottlieb, E; Schug, ZT; Vande Voorde, J	1
Cuyàs, E; Fernández-Arroyo, S; Joven, J; Menendez, JA	1
van der Knaap, JA; Verrijzer, CP	1
Lincet, H	1
Fujibayashi, Y; Furukawa, T; Kiyono, Y; Kobayashi, M; Kudo, T; Mori, T; Okazawa, H; Tsujikawa, T; Waki, A; Yonekura, Y; Yoshii, H; Yoshii, Y	1
Cha, JH; Chun, KH; Ha, JY; Han, SH; Jeong, CH; Jeong, JW; Kang, JH; Kim, KH; Kim, KW; Kim, SH; Kwon, SW; Lee, HS; Lee, JW; Lee, KJ; Lee, MN; Lee, SJ; Lee, SK; Oh, GT; Oh, SH; Park, JA; Park, JH; Park, ZY; Seo, JH; Suh, SW	1
Ponisovskiy, MR	1
Chandel, NS; Chen, PH; Cheng, T; DeBerardinis, RJ; Jin, ES; Linehan, WM; Mullen, AR; Sullivan, LB; Wheaton, WW; Yang, Y	1
Jackowski, S; Leonardi, R; Rock, CO; Subramanian, C	1
Gevers, W; Levin, L	1
Kamataki, T; Kato, R; Saito, K; Shinohara, A	1

Reviews

24 review(s) available for acetyl coenzyme a and Neoplasms

Article	Year
Metabolic Regulation of Lysine Acetylation: Implications in Cancer. Sub-cellular biochemistry, 2022, Volume: 100 Topics: Acetyl Coenzyme A; Acetylation; Humans; Lysine; NAD; Neoplasms; Protein Processing, Post-Translational	2022
Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer. Biochimica et biophysica acta. Reviews on cancer, 2023, Volume: 1878, Issue:1 Topics: Acetyl Coenzyme A; Acetylation; Histones; Humans; Lipid Metabolism; Neoplasms; Protein Processing, Post-Translational	2023
Acetyl-CoA metabolism in cancer. Nature reviews. Cancer, 2023, Volume: 23, Issue:3 Topics: Acetyl Coenzyme A; Animals; Disease Models, Animal; Humans; Metabolic Networks and Pathways; Mice; Neoplasms	2023
ATP citrate lyase: A central metabolic enzyme in cancer. Cancer letters, 2020, 02-28, Volume: 471 Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; Humans; Neoplasms; Oxaloacetic Acid; Structure-Activity Relationship	2020
Metabolic Control of Epigenetics and Its Role in CD8 Frontiers in immunology, 2019, Volume: 10 Topics: Acetyl Coenzyme A; Animals; CD8-Positive T-Lymphocytes; Cell Differentiation; Cellular Senescence; Epigenesis, Genetic; Epigenomics; Histones; Humans; Immunologic Surveillance; Immunotherapy, Adoptive; Lymphocyte Activation; Neoplasms; Tumor Microenvironment; Virus Diseases	2019
Melatonin in Mitochondria: Mitigating Clear and Present Dangers. Physiology (Bethesda, Md.), 2020, 03-01, Volume: 35, Issue:2 Topics: Acetyl Coenzyme A; Animals; Glucose; Humans; Melatonin; Mitochondria; Neoplasms; Reactive Oxygen Species	2020
Tumour Microenvironment: Roles of the Aryl Hydrocarbon Receptor, O-GlcNAcylation, Acetyl-CoA and Melatonergic Pathway in Regulating Dynamic Metabolic Interactions across Cell Types-Tumour Microenvironment and Metabolism. International journal of molecular sciences, 2020, Dec-25, Volume: 22, Issue:1 Topics: Acetyl Coenzyme A; Age Factors; Animals; Basic Helix-Loop-Helix Transcription Factors; Computational Biology; Humans; Immunomodulation; Melatonin; Metabolic Networks and Pathways; Mitochondria; Models, Biological; Neoplasms; Organ Specificity; Receptors, Aryl Hydrocarbon; Sirtuins; Tumor Microenvironment	2020
Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases. International journal of molecular sciences, 2021, Jan-14, Volume: 22, Issue:2 Topics: Acetyl Coenzyme A; Animals; Glucose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Melatonin; Mitochondria; Neoplasms; Pentose Phosphate Pathway; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Warburg Effect, Oncologic	2021
Emerging roles of lipid metabolism in cancer progression. Current opinion in clinical nutrition and metabolic care, 2017, Volume: 20, Issue:4 Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Animals; Citric Acid Cycle; Drug Resistance, Neoplasm; Fatty Acids; Humans; Lipid Metabolism; Neoplasm Metastasis; Neoplasms; Obesity; Oxidation-Reduction; Stromal Cells	2017
The role of OXCT1 in the pathogenesis of cancer as a rate-limiting enzyme of ketone body metabolism. Life sciences, 2017, Aug-15, Volume: 183 Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Coenzyme A-Transferases; Gene Expression Regulation, Neoplastic; Humans; Ketones; Neoplasms; Signal Transduction	2017
Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer. Journal of the National Cancer Institute, 2017, 11-01, Volume: 109, Issue:11 Topics: Acetyl Coenzyme A; Adenosine Triphosphate; Biomimetics; Citric Acid Cycle; Dichloroacetic Acid; Energy Metabolism; Glycolysis; Humans; Isoenzymes; Mitochondria; NAD; Neoplasms; Oxidative Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Pyruvate Dehydrogenase Complex; Pyruvic Acid	2017
Acetate Metabolism in Physiology, Cancer, and Beyond. Trends in cell biology, 2019, Volume: 29, Issue:9 Topics: Acetates; Acetyl Coenzyme A; Acetylation; Glucose; Glycolysis; Humans; Lipogenesis; Mitochondria; Neoplasms	2019
Metabolic Intermediates in Tumorigenesis and Progression. International journal of biological sciences, 2019, Volume: 15, Issue:6 Topics: Acetyl Coenzyme A; Antineoplastic Agents; Carcinogenesis; Cell Proliferation; Disease Progression; Flavin-Adenine Dinucleotide; Humans; NAD; Neoplasm Invasiveness; Neoplasms; S-Adenosylmethionine; Tetrahydrofolates	2019
Acetate/acetyl-CoA metabolism associated with cancer fatty acid synthesis: overview and application. Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt A Topics: Acetates; Acetyl Coenzyme A; Cell Hypoxia; Coenzyme A Ligases; Fatty Acids; Humans; Lipogenesis; Neoplasms; Positron-Emission Tomography; Precision Medicine; Up-Regulation	2015
Metabolism and epigenetics: a link cancer cells exploit. Current opinion in biotechnology, 2015, Volume: 34 Topics: Acetyl Coenzyme A; Acetylation; Animals; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histones; Humans; Neoplasms	2015
Metabolic regulation of histone post-translational modifications. ACS chemical biology, 2015, Jan-16, Volume: 10, Issue:1 Topics: Acetyl Coenzyme A; Acetylation; Adaptation, Physiological; Animals; DNA Methylation; Epigenesis, Genetic; Histone Deacetylases; Histones; Humans; Neoplasms; Protein Processing, Post-Translational; Transcription, Genetic	2015
Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer. Current opinion in clinical nutrition and metabolic care, 2015, Volume: 18, Issue:4 Topics: Acetates; Acetyl Coenzyme A; Cell Line, Tumor; Citrates; Citric Acid Cycle; Glucose; Glutamine; Humans; Hypoxia; Ketoglutaric Acids; Lipogenesis; Neoplasms	2015
Acetate as a Metabolic and Epigenetic Modifier of Cancer Therapy. Journal of cellular biochemistry, 2016, Volume: 117, Issue:3 Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Acetylation; Animals; Carcinogenesis; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Signal Transduction	2016
Cancer metabolism: a therapeutic perspective. Nature reviews. Clinical oncology, 2017, Volume: 14, Issue:1 Topics: Acetyl Coenzyme A; Adaptation, Physiological; Amino Acids; Antineoplastic Agents; Antioxidants; Autophagy; Blood Glucose; Energy Metabolism; Epigenomics; Fatty Acids; Genetic Heterogeneity; Glutamic Acid; Glutamine; Humans; Ketone Bodies; Lactic Acid; Lipids; Mitochondria; Mitochondrial Ribosomes; Neoplasms; Nucleic Acids; Oxidative Stress; Pyruvic Acid; TOR Serine-Threonine Kinases; Transcription Factors; Tumor Microenvironment	2017
The metabolic fate of acetate in cancer. Nature reviews. Cancer, 2016, Volume: 16, Issue:11 Topics: Acetates; Acetyl Coenzyme A; Gastrointestinal Microbiome; Humans; Metabolic Networks and Pathways; Neoplasms; Signal Transduction	2016
Undercover: gene control by metabolites and metabolic enzymes. Genes & development, 2016, 11-01, Volume: 30, Issue:21 Topics: Acetyl Coenzyme A; Animals; Cell Nucleus; Chromatin; Gene Expression Regulation; Histones; Humans; Metabolism; NAD; Neoplasms; Pluripotent Stem Cells	2016
The reduced concentration of citrate in cancer cells: An indicator of cancer aggressiveness and a possible therapeutic target. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2016, Volume: 29 Topics: Acetyl Coenzyme A; Apoptosis; ATP Citrate (pro-S)-Lyase; Biomarkers, Tumor; Citric Acid; Citric Acid Cycle; Epigenesis, Genetic; Glycolysis; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Invasiveness; Neoplasms; Oxidative Phosphorylation; Prognosis	2016
Cancer metabolism and the Warburg effect as anabolic process outcomes of oncogene operation. Critical reviews in eukaryotic gene expression, 2010, Volume: 20, Issue:4 Topics: Acetyl Coenzyme A; Animals; Apoptosis; Glycolysis; Humans; Models, Biological; Neoplasm Metastasis; Neoplasms; Oncogenes	2010
Metabolic alterations in cancer. Part I. Carbohydrate metabolism. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Apr-04, Volume: 59, Issue:15 Topics: Acetyl Coenzyme A; Amino Acids; Animals; Female; Gluconeogenesis; Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Lactates; Metabolic Diseases; Neoplasms; Protein Deficiency; Pyruvate Carboxylase; Rats; Substrate Specificity	1981

Other Studies

28 other study(ies) available for acetyl coenzyme a and Neoplasms

Article	Year
Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation. Genes, 2021, 09-21, Volume: 12, Issue:9 Topics: Acetyl Coenzyme A; Acetylation; ATP Citrate (pro-S)-Lyase; Cell Adhesion; Cell Line, Tumor; Cell Movement; Gene Expression Regulation; HEK293 Cells; Histones; Humans; Neoplasms; Phenotype; Sirtuins	2021
Biocatalysis of precursors to new-generation SB-T-taxanes effective against paclitaxel-resistant cancer cells. Archives of biochemistry and biophysics, 2022, 04-15, Volume: 719 Topics: Acetyl Coenzyme A; Acetyltransferases; Biocatalysis; Neoplasms; Paclitaxel; Substrate Specificity; Tandem Mass Spectrometry; Taxoids	2022
Intracellular Acetyl CoA Potentiates the Therapeutic Efficacy of Antitumor CD8+ T Cells. Cancer research, 2022, 07-18, Volume: 82, Issue:14 Topics: Acetyl Coenzyme A; Animals; ATP Citrate (pro-S)-Lyase; CD8-Positive T-Lymphocytes; Humans; Interleukin-12; Mice; Neoplasms; Tumor Microenvironment	2022
Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition. Nature chemical biology, 2023, Volume: 19, Issue:10 Topics: Acetyl Coenzyme A; Histone Acetyltransferases; Humans; Neoplasms; p300-CBP Transcription Factors; Protein Binding	2023
Caspase-10 inhibits ATP-citrate lyase-mediated metabolic and epigenetic reprogramming to suppress tumorigenesis. Nature communications, 2019, 09-18, Volume: 10, Issue:1 Topics: A549 Cells; Acetyl Coenzyme A; Acetylation; Animals; ATP Citrate (pro-S)-Lyase; Carcinogenesis; Caspase 10; Cell Line, Tumor; Cell Proliferation; Epigenesis, Genetic; Female; HCT116 Cells; HEK293 Cells; Histones; Humans; Lipogenesis; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; p300-CBP Transcription Factors; Transplantation, Heterologous	2019
Aspirin Reshapes Acetylomes in Inflammatory and Cancer Cells via CoA-Dependent and CoA-Independent Pathways. Journal of proteome research, 2020, 02-07, Volume: 19, Issue:2 Topics: Acetyl Coenzyme A; Acetylation; Aspirin; Humans; Lysine; Neoplasms; Protein Processing, Post-Translational; Proteome	2020
Inhibition of the ketolytic acetyl CoA supply to tumors could be their "Achilles heel". International journal of cancer, 2020, 09-15, Volume: 147, Issue:6 Topics: Acetyl Coenzyme A; Antineoplastic Agents; Coenzyme A-Transferases; Combined Modality Therapy; Diet, Ketogenic; Humans; Liver; Mitochondria; Neoplasms; Warburg Effect, Oncologic	2020
Comments on "Inhibition of the ketolytic acetyl CoA supply to tumors could be their 'Achilles heel'". International journal of cancer, 2020, 12-01, Volume: 147, Issue:11 Topics: Acetyl Coenzyme A; Humans; Neoplasms	2020
NatB regulates Rb mutant cell death and tumor growth by modulating EGFR/MAPK signaling through the N-end rule pathways. PLoS genetics, 2020, Volume: 16, Issue:6 Topics: Acetyl Coenzyme A; Acetylation; Alleles; Animals; Animals, Genetically Modified; Apoptosis; Blood Proteins; Cell Proliferation; Cell Survival; Disease Models, Animal; Drosophila Proteins; ErbB Receptors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; MAP Kinase Signaling System; N-Terminal Acetyltransferase B; Neoplasms; Receptors, Invertebrate Peptide; Retinoblastoma Protein; Synthetic Lethal Mutations; Transcription Factors	2020
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature, 2017, 10-05, Volume: 550, Issue:7674 Topics: Acetyl Coenzyme A; Animals; Antineoplastic Agents; Binding, Competitive; Biocatalysis; Catalytic Domain; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Crystallography, X-Ray; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Hematologic Neoplasms; Heterocyclic Compounds, 4 or More Rings; Histone Acetyltransferases; Humans; Male; Mice; Mice, SCID; Models, Molecular; Neoplasms; p300-CBP Transcription Factors; Prostatic Neoplasms, Castration-Resistant; Protein Conformation; Receptors, Androgen; Xenograft Model Antitumor Assays	2017
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase. Nature, 2017, 12-14, Volume: 552, Issue:7684 Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Crystallography, X-Ray; Female; Gene Expression Regulation; Histone Acetyltransferases; Histones; Humans; Ketoglutarate Dehydrogenase Complex; Lysine; Mice; Models, Molecular; Mutagenesis, Site-Directed; Neoplasms; Protein Binding; Protein Domains; Transcription Initiation Site; Tyrosine	2017
Coordinate regulation of stress signaling and epigenetic events by Acss2 and HIF-2 in cancer cells. PloS one, 2017, Volume: 12, Issue:12 Topics: Acetate-CoA Ligase; Acetyl Coenzyme A; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Epigenesis, Genetic; HEK293 Cells; Humans; Lysine; Mice; Mice, Nude; Neoplasms; Oxidative Stress; Real-Time Polymerase Chain Reaction; Signal Transduction	2017
Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: A novel evidence-based medical hypothesis. Medical hypotheses, 2019, Volume: 122 Topics: Acetates; Acetyl Coenzyme A; Animals; Antineoplastic Agents; Brain Neoplasms; Chlorides; Dichloroacetic Acid; Evidence-Based Medicine; Glioblastoma; Heart; Humans; Ketones; Lactic Acid; Models, Theoretical; Neoplasms; Oxygen; Perfusion; Rats	2019
Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia. Nature communications, 2019, 01-14, Volume: 10, Issue:1 Topics: Acetyl Coenzyme A; Ammonia; Animals; Carbon; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Female; Glucose; Glutamine; HEK293 Cells; Humans; Lactic Acid; Lipogenesis; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Mice, Nude; Neoplasms; Nitrogen; Nucleotides; Orotic Acid; Tumor Microenvironment; Xenograft Model Antitumor Assays	2019
T cell stemness and dysfunction in tumors are triggered by a common mechanism. Science (New York, N.Y.), 2019, 03-29, Volume: 363, Issue:6434 Topics: Acetyl Coenzyme A; Acetylation; Animals; Autophagy; Caloric Restriction; CD8-Positive T-Lymphocytes; Cell Differentiation; Epigenesis, Genetic; Histones; Humans; Immune Tolerance; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Neoplasms; Potassium; Stem Cells; Tumor Microenvironment	2019
CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program. Monoclonal antibodies in immunodiagnosis and immunotherapy, 2019, Volume: 38, Issue:2 Topics: Acetyl Coenzyme A; Antibodies, Monoclonal; CD28 Antigens; CD4-Positive T-Lymphocytes; Cell Proliferation; Glucose; Glycolysis; Humans; Immunologic Memory; Lipogenesis; Lymphocyte Activation; Neoplasms; Protein Kinases; T-Lymphocytes, Regulatory; Tumor Cells, Cultured	2019
Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, May-14, Volume: 34, Issue:20 Topics: Acetyl Coenzyme A; Acetylation; Animals; Endoplasmic Reticulum; Infections; Inflammation; Mice; Mice, Transgenic; Neoplasms; Nerve Degeneration	2014
ATP-citrate lyase regulates cellular senescence via an AMPK- and p53-dependent pathway. The FEBS journal, 2015, Volume: 282, Issue:2 Topics: Acetyl Coenzyme A; AMP-Activated Protein Kinases; Animals; ATP Citrate (pro-S)-Lyase; Carcinogenesis; Cellular Senescence; Cytosol; Gene Expression Regulation, Enzymologic; Gene Knockdown Techniques; HEK293 Cells; Humans; Neoplasms; Rats; Signal Transduction; Tumor Suppressor Protein p53	2015
Acetate dependence of tumors. Cell, 2014, Dec-18, Volume: 159, Issue:7 Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Animals; Humans; Immunohistochemistry; Liver Neoplasms; Mice; Neoplasms; Positron-Emission Tomography; Triple Negative Breast Neoplasms	2014
Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells. Biochemical and biophysical research communications, 2016, Mar-18, Volume: 471, Issue:4 Topics: Acetyl Coenzyme A; Acetylation; ATP Citrate (pro-S)-Lyase; Carrier Proteins; Gene Knockdown Techniques; Humans; Lipogenesis; Neoplasms; Proteasome Endopeptidase Complex; Proteins; Proteolysis; Spermidine; Two-Hybrid System Techniques	2016
Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate. Oncotarget, 2016, Jul-26, Volume: 7, Issue:30 Topics: Acetyl Coenzyme A; Adaptation, Physiological; Adenosine Triphosphate; Cell Proliferation; Electron Transport; Glycolysis; Humans; NAD; Neoplasms; Oxaloacetic Acid; Oxygen; Pyruvic Acid; TOR Serine-Threonine Kinases	2016
Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation. Cell metabolism, 2016, 08-09, Volume: 24, Issue:2 Topics: Acetyl Coenzyme A; Acetylation; Acidosis; Animals; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Cellular Reprogramming; Electron Transport Complex I; Fatty Acids; Female; Glutamine; Histones; Humans; Hydrogen-Ion Concentration; Metabolic Networks and Pathways; Mice, Nude; Mitochondria; Models, Biological; Neoplasms; Oxidation-Reduction; Reactive Oxygen Species	2016
Metformin targets histone acetylation in cancer-prone epithelial cells. Cell cycle (Georgetown, Tex.), 2016, Dec-16, Volume: 15, Issue:24 Topics: Acetyl Coenzyme A; Acetylation; BRCA1 Protein; Carcinogenesis; Epigenesis, Genetic; Epithelial Cells; Genomic Instability; Haploinsufficiency; Histones; Metformin; Models, Biological; Neoplasms	2016
Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism. Cancer science, 2009, Volume: 100, Issue:5 Topics: Acetate-CoA Ligase; Acetates; Acetyl Coenzyme A; Animals; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cytosol; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Mice; Neoplasms; RNA Interference	2009
Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation. Cancer research, 2010, Jun-01, Volume: 70, Issue:11 Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Animals; beta Catenin; Cell Growth Processes; Cyclin D1; HeLa Cells; Humans; Mice; N-Terminal Acetyltransferase A; N-Terminal Acetyltransferase E; Neoplasms; Transcription Factor AP-1; Up-Regulation	2010
Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature, 2011, Nov-20, Volume: 481, Issue:7381 Topics: Acetyl Coenzyme A; Animals; Carcinoma, Renal Cell; Cell Hypoxia; Cell Line, Tumor; Citric Acid; Electron Transport; Electron Transport Complex I; Electron Transport Complex III; Fumarate Hydratase; Glucose; Glutamine; Humans; Isocitrate Dehydrogenase; Kidney Neoplasms; Mice; Mitochondria; NADP; Neoplasms	2011
Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation. The Journal of biological chemistry, 2012, Apr-27, Volume: 287, Issue:18 Topics: Acetyl Coenzyme A; Cell Hypoxia; Cell Line, Tumor; Humans; Isocitrate Dehydrogenase; Mitochondria; Mitochondrial Proteins; Mutation; NADP; Neoplasm Proteins; Neoplasms; Oxidation-Reduction	2012
Acetyl-CoA dependent O-acetylation of N-hydroxyarylamines in bacterial and mammalian cells--the significance for mutagenesis and carcinogenesis. Progress in clinical and biological research, 1986, Volume: 209A Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Animals; Biotransformation; Carcinogens; Cricetinae; Hydroxylamines; Liver; Mutagens; Mutation; Neoplasms; Rats; Salmonella typhimurium	1986