acetyl-adenylate and Chromosome-Deletion

acetyl-adenylate has been researched along with Chromosome-Deletion* in 1 studies

Other Studies

1 other study(ies) available for acetyl-adenylate and Chromosome-Deletion

Article	Year
Acetyladenylate plays a role in controlling the direction of flagellar rotation. Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:18 Cells of Escherichia coli deleted for genes that code for the transducers and all the known cytoplasmic Che proteins except CheY responded reversibly to the addition of acetate by spinning their flagellar motors clockwise. By varying growth conditions and using metabolic inhibitors and mutants deficient in acetate metabolism, this effect was shown to require acetate-CoA synthetase [acetate:CoA ligase (AMP-forming); EC 6.2.1.1], an enzyme that catalyzes the formation of acetyl-CoA from acetate by an acetyladenylate intermediate. A mutant deficient in this enzyme but retaining the chemotaxis genes was deficient for chemotaxis. Thus, acetyladenylate appears to play a role in generating clockwise rotation at the level of CheY or the motor. Topics: Acetate-CoA Ligase; Acetates; Acetic Acid; Adenosine Monophosphate; Adenosine Triphosphate; Chemotaxis; Chromosome Deletion; Citric Acid Cycle; Escherichia coli; Flagella; Glycolysis	1988

Article

Year

Acetyladenylate plays a role in controlling the direction of flagellar rotation.

Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:18

Cells of Escherichia coli deleted for genes that code for the transducers and all the known cytoplasmic Che proteins except CheY responded reversibly to the addition of acetate by spinning their flagellar motors clockwise. By varying growth conditions and using metabolic inhibitors and mutants deficient in acetate metabolism, this effect was shown to require acetate-CoA synthetase [acetate:CoA ligase (AMP-forming); EC 6.2.1.1], an enzyme that catalyzes the formation of acetyl-CoA from acetate by an acetyladenylate intermediate. A mutant deficient in this enzyme but retaining the chemotaxis genes was deficient for chemotaxis. Thus, acetyladenylate appears to play a role in generating clockwise rotation at the level of CheY or the motor.

Topics: Acetate-CoA Ligase; Acetates; Acetic Acid; Adenosine Monophosphate; Adenosine Triphosphate; Chemotaxis; Chromosome Deletion; Citric Acid Cycle; Escherichia coli; Flagella; Glycolysis

1988