acetovanillone has been researched along with Reperfusion Injury in 43 studies
apocynin : An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preconditioning with sevoflurane (SEV) can protect against ischemia-reperfusion injury in several organs, however, the benefits of SEV against acute lung injury (ALI), induced by intestinal ischemia-reperfusion (IIR), and the underlying mechanisms remain to be elucidated." | 3.81 | Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress. ( Chen, H; Hei, Z; Luo, C; Luo, G; Su, G; Yuan, D; Zhao, W, 2015) |
| "Allopurinol and apocynin exerted protective effects on hepatic ischemia/reperfusion injury." | 3.74 | Protective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice. ( He, SQ; Liu, PG; Wu, J; Zhang, YH, 2008) |
| "Renal ischemia/reperfusion injury is a common cause of acute kidney injury (AKI) and hypertension might contribute to the increased incidence of AKI." | 1.56 | Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats. ( Brkic, P; Ivanov, M; Jeremic, R; Jovovic, D; Karanovic, D; Kovacevic, S; Mihailovic-Stanojevic, N; Miloradovic, Z; Nesovic-Ostojic, J; Vajic, UJ; Zivotic, M, 2020) |
| "Stroke is a universal cause of death and permanent disability." | 1.46 | Adiponectin attenuates NADPH oxidase-mediated oxidative stress and neuronal damage induced by cerebral ischemia-reperfusion injury. ( Bai, H; Feng, D; Gao, L; Guo, H; Jiang, H; Li, X; Liu, H; Qu, Y; Wang, B; Yue, L; Zhao, L, 2017) |
| "Kidney fibrosis is a typical feature of chronic kidney disease and is characterized as an expansion of the interstitium due to increases in extracellular matrix molecules and interstitial cells caused by accumulations of extrarenal cells and by the proliferation or differentiation of intrarenal cells." | 1.40 | Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis. ( Han, SJ; Jang, HS; Kim, JI; Park, KM, 2014) |
| "Two hours after the end of EA pretreatment, focal cerebral ischemia was induced following 24h reperfusion." | 1.40 | Electroacupuncture pretreatment inhibits NADPH oxidase-mediated oxidative stress in diabetic mice with cerebral ischemia. ( Guo, F; Jiang, T; Liu, L; Song, W; Wang, F; Wang, Q; Xiong, L; Yin, H; Zhong, H, 2014) |
| "Diabetic EPCs demonstrate reduced eNOS expression and decreased NO bioavailability and migration in response to SDF-1α." | 1.37 | Blockade of NADPH oxidase restores vasoreparative function in diabetic CD34+ cells. ( Caballero, S; Grant, MB; Jarajapu, YP; Li, Q; Lo, MC; Nakagawa, T; Verma, A, 2011) |
| "The present study was designed to determine a dose-response relationship between apocynin and infarct volume as well as to provide a possible molecular mechanism mediating this effect." | 1.37 | Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis. ( Connell, BJ; Khan, BV; Saleh, MC; Saleh, TM, 2011) |
| "SAO shock is a severe form of circulatory shock produced by I/R of the splanchnic organs." | 1.36 | Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion. ( Bramanti, P; Cuzzocrea, S; Esposito, E; Galuppo, M; Impellizzeri, D; Mazzon, E; Paterniti, I, 2010) |
| "Lung injury was assessed by measuring vascular permeability (via Evans blue dye), edema, neutrophil infiltration (via myeloperoxidase [MPO]), lipid peroxidation (via malondialdyhyde [MDA]), and expression of proinflammatory cytokines." | 1.35 | NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury. ( Kron, IL; Laubach, VE; Marshall, M; Sharma, AK; Yang, Z, 2009) |
| "Global cerebral ischemia was induced in gerbils by a 5-min occlusion of bilateral common carotid arteries (CCA)." | 1.33 | Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus. ( Korthuis, RJ; Simonyi, A; Sun, AY; Sun, GY; Tompkins, KD; Wang, Q, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.33) | 18.2507 |
| 2000's | 10 (23.26) | 29.6817 |
| 2010's | 30 (69.77) | 24.3611 |
| 2020's | 2 (4.65) | 2.80 |
| Authors | Studies |
|---|---|
| Arrault, A | 1 |
| Dubuisson, M | 1 |
| Gharbi, S | 1 |
| Marchand, C | 1 |
| Verbeuren, T | 2 |
| Rupin, A | 1 |
| Cordi, A | 2 |
| Bouskela, E | 2 |
| Rees, JF | 2 |
| Marchand-Brynaert, J | 2 |
| De Wael, F | 1 |
| Jeanjot, P | 1 |
| Moens, C | 1 |
| Tanyeli, A | 1 |
| Guzel Erdogan, D | 1 |
| Comakli, S | 1 |
| Polat, E | 1 |
| Guler, MC | 1 |
| Eraslan, E | 1 |
| Doganay, S | 1 |
| Kovacevic, S | 1 |
| Ivanov, M | 1 |
| Miloradovic, Z | 1 |
| Brkic, P | 1 |
| Vajic, UJ | 1 |
| Zivotic, M | 1 |
| Mihailovic-Stanojevic, N | 1 |
| Jovovic, D | 1 |
| Karanovic, D | 1 |
| Jeremic, R | 1 |
| Nesovic-Ostojic, J | 1 |
| Zhang, S | 1 |
| Tan, X | 1 |
| Chen, Y | 1 |
| Zhang, X | 1 |
| Li, X | 1 |
| Guo, H | 1 |
| Zhao, L | 1 |
| Wang, B | 1 |
| Liu, H | 1 |
| Yue, L | 1 |
| Bai, H | 1 |
| Jiang, H | 1 |
| Gao, L | 1 |
| Feng, D | 1 |
| Qu, Y | 1 |
| Arumugam, S | 1 |
| Girish Subbiah, K | 1 |
| Kemparaju, K | 1 |
| Thirunavukkarasu, C | 1 |
| Kapoor, M | 1 |
| Sharma, N | 1 |
| Sandhir, R | 1 |
| Nehru, B | 1 |
| Cananzi, SG | 1 |
| Mayhan, WG | 2 |
| Yücel, A | 1 |
| Aydogan, MS | 1 |
| Ucar, M | 1 |
| Sarıcı, KB | 1 |
| Karaaslan, MG | 1 |
| Tang, X | 1 |
| Zhong, W | 1 |
| Tu, Q | 1 |
| Ding, B | 1 |
| Jang, HS | 2 |
| Kim, JI | 2 |
| Han, SJ | 1 |
| Park, KM | 2 |
| Guo, F | 1 |
| Song, W | 1 |
| Jiang, T | 1 |
| Liu, L | 1 |
| Wang, F | 1 |
| Zhong, H | 1 |
| Yin, H | 1 |
| Wang, Q | 3 |
| Xiong, L | 1 |
| Zhao, W | 2 |
| Zhou, S | 1 |
| Yao, W | 1 |
| Gan, X | 1 |
| Su, G | 2 |
| Yuan, D | 2 |
| Hei, Z | 2 |
| Ozbek, O | 1 |
| Altintas, R | 2 |
| Polat, A | 2 |
| Vardi, N | 2 |
| Parlakpinar, H | 2 |
| Sagir, M | 2 |
| Duran, ZR | 1 |
| Yildiz, A | 2 |
| Şener, TE | 1 |
| Yüksel, M | 1 |
| Özyılmaz-Yay, N | 1 |
| Ercan, F | 1 |
| Akbal, C | 1 |
| Şimşek, F | 1 |
| Şener, G | 1 |
| Luo, C | 1 |
| Chen, H | 1 |
| Luo, G | 1 |
| Hu, B | 1 |
| Wu, Y | 1 |
| Tong, F | 1 |
| Liu, J | 1 |
| Shen, X | 1 |
| Shen, R | 1 |
| Xu, G | 1 |
| Qin, YY | 1 |
| Li, M | 1 |
| Feng, X | 1 |
| Wang, J | 1 |
| Cao, L | 1 |
| Shen, XK | 1 |
| Chen, J | 1 |
| Sun, M | 1 |
| Sheng, R | 1 |
| Han, F | 1 |
| Qin, ZH | 1 |
| Yang, Z | 1 |
| Sharma, AK | 1 |
| Marshall, M | 1 |
| Kron, IL | 1 |
| Laubach, VE | 1 |
| Zhu, C | 1 |
| Bilali, A | 1 |
| Georgieva, GS | 1 |
| Kurata, S | 1 |
| Mitaka, C | 1 |
| Imai, T | 1 |
| Kim, GS | 1 |
| Jung, JE | 1 |
| Niizuma, K | 1 |
| Chan, PH | 1 |
| Phillips, SA | 1 |
| Pechman, KR | 1 |
| Leonard, EC | 2 |
| Friedrich, JL | 1 |
| Bian, JT | 1 |
| Beal, AG | 2 |
| Basile, DP | 2 |
| Zhao, H | 1 |
| Arrick, DM | 1 |
| Xiong, W | 1 |
| Sun, H | 1 |
| Paterniti, I | 2 |
| Galuppo, M | 1 |
| Mazzon, E | 2 |
| Impellizzeri, D | 1 |
| Esposito, E | 2 |
| Bramanti, P | 2 |
| Cuzzocrea, S | 2 |
| Genovese, T | 1 |
| Woodfin, A | 1 |
| Hu, DE | 1 |
| Sarker, M | 1 |
| Kurokawa, T | 1 |
| Fraser, P | 1 |
| Murotomi, K | 1 |
| Takagi, N | 1 |
| Takeo, S | 1 |
| Tanonaka, K | 1 |
| Shen, J | 1 |
| Bai, XY | 1 |
| Qin, Y | 1 |
| Jin, WW | 1 |
| Zhou, JY | 1 |
| Zhou, JP | 1 |
| Yan, YG | 1 |
| Bruce, IC | 1 |
| Chen, JH | 1 |
| Xia, Q | 1 |
| Jarajapu, YP | 1 |
| Caballero, S | 1 |
| Verma, A | 1 |
| Nakagawa, T | 1 |
| Lo, MC | 1 |
| Li, Q | 1 |
| Grant, MB | 1 |
| Chiang, CH | 1 |
| Chuang, CH | 1 |
| Liu, SL | 1 |
| Connell, BJ | 3 |
| Saleh, MC | 2 |
| Khan, BV | 2 |
| Saleh, TM | 3 |
| Rajagopal, D | 1 |
| Schleuter, D | 1 |
| Friedrich, J | 1 |
| Kim, J | 1 |
| Na, YK | 1 |
| Park, JW | 1 |
| Oguz, F | 1 |
| Beytur, A | 1 |
| Tompkins, KD | 1 |
| Simonyi, A | 1 |
| Korthuis, RJ | 2 |
| Sun, AY | 1 |
| Sun, GY | 1 |
| Yusof, M | 1 |
| Kamada, K | 1 |
| Gaskin, FS | 1 |
| Shiotani, S | 1 |
| Shimada, M | 1 |
| Taketomi, A | 1 |
| Soejima, Y | 1 |
| Yoshizumi, T | 1 |
| Hashimoto, K | 1 |
| Shimokawa, H | 1 |
| Maehara, Y | 1 |
| Liu, PG | 1 |
| He, SQ | 1 |
| Zhang, YH | 1 |
| Wu, J | 1 |
| Pearse, DB | 2 |
| Dodd, JM | 1 |
| Dodd-O, JM | 1 |
43 other studies available for acetovanillone and Reperfusion Injury
| Article | Year |
|---|---|
Protective effect of imidazolopyrazinone antioxidants on ischemia/reperfusion injury.
Topics: Amidines; Animals; Antioxidants; Capillary Permeability; Cricetinae; Firefly Luciferin; Imidazoles; | 2003 |
In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants.
Topics: Amines; Animals; Antioxidants; Capillary Permeability; Chromatography, High Pressure Liquid; Criceti | 2009 |
Therapeutic effects of apocynin on ovarian ischemia-reperfusion induced lung injury.
Topics: Acetophenones; Animals; Ischemia; Lung; Lung Injury; Oxidative Stress; Rats; Reperfusion; Reperfusio | 2022 |
Hyperbaric oxygen preconditioning and the role of NADPH oxidase inhibition in postischemic acute kidney injury induced in spontaneously hypertensive rats.
Topics: Acetophenones; Acute Kidney Injury; Animals; Enzyme Inhibitors; Hyperbaric Oxygenation; Male; NADPH | 2020 |
Postconditioning protects renal fibrosis by attenuating oxidative stress-induced mitochondrial injury.
Topics: Acetophenones; Animals; Antioxidants; Cell Line; DNA Damage; DNA, Mitochondrial; Epithelial-Mesenchy | 2017 |
Adiponectin attenuates NADPH oxidase-mediated oxidative stress and neuronal damage induced by cerebral ischemia-reperfusion injury.
Topics: Acetophenones; Adiponectin; Animals; Apoptosis; Brain Ischemia; Disease Models, Animal; DNA Nucleoti | 2017 |
Neutrophil extracellular traps in acrolein promoted hepatic ischemia reperfusion injury: Therapeutic potential of NOX2 and p38MAPK inhibitors.
Topics: Acetophenones; Acrolein; Animals; Antioxidants; Apoptosis; Cell Death; Cell Nucleus; Chemotaxis; DNA | 2018 |
Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion hippocampus injury in rat brain.
Topics: Acetophenones; Animals; Brain Ischemia; Enzyme Inhibitors; Hippocampus; Male; Maze Learning; NADPH O | 2018 |
In Utero Exposure to Alcohol Impairs Reactivity of Cerebral Arterioles and Increases Susceptibility of the Brain to Damage Following Ischemia/Reperfusion in Adulthood.
Topics: Acetophenones; Adenosine Diphosphate; Animals; Arterioles; Brain; Enzyme Inhibitors; Ethanol; Excita | 2019 |
Effects of Apocynin on Liver Ischemia-Reperfusion Injury in Rats.
Topics: Acetophenones; Animals; Antioxidants; Female; Liver; Oxidative Stress; Rats; Rats, Sprague-Dawley; R | 2019 |
NADPH oxidase mediates the expression of MMP-9 in cerebral tissue after ischemia-reperfusion damage.
Topics: Acetophenones; Animals; Blotting, Western; Brain; Brain Ischemia; Enzyme Inhibitors; Infarction, Mid | 2014 |
Recruitment and subsequent proliferation of bone marrow-derived cells in the postischemic kidney are important to the progression of fibrosis.
Topics: Acetophenones; Acute Kidney Injury; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Pr | 2014 |
Electroacupuncture pretreatment inhibits NADPH oxidase-mediated oxidative stress in diabetic mice with cerebral ischemia.
Topics: Acetophenones; Animals; Brain; Brain Ischemia; Cinnamates; Diabetes Mellitus, Experimental; Electroa | 2014 |
Propofol prevents lung injury after intestinal ischemia-reperfusion by inhibiting the interaction between mast cell activation and oxidative stress.
Topics: Acetophenones; Acute Lung Injury; Animals; Cell Degranulation; Enzyme-Linked Immunosorbent Assay; Hy | 2014 |
The protective effect of apocynin on testicular ischemia-reperfusion injury.
Topics: Acetophenones; Animals; Enzyme Inhibitors; Male; Rats; Rats, Wistar; Reperfusion Injury; Spermatic C | 2015 |
Apocynin attenuates testicular ischemia-reperfusion injury in rats.
Topics: Acetophenones; Animals; Biomarkers; Enzyme Inhibitors; Male; Oxidative Stress; Rats; Rats, Wistar; R | 2015 |
Sevoflurane ameliorates intestinal ischemia-reperfusion-induced lung injury by inhibiting the synergistic action between mast cell activation and oxidative stress.
Topics: Acetophenones; Acute Lung Injury; Anesthetics, Inhalation; Animals; Antioxidants; Cell Degranulation | 2015 |
Apocynin Alleviates Renal Ischemia/Reperfusion Injury Through Regulating the Level of Zinc and Metallothionen.
Topics: Acetophenones; Animals; Cytokines; Kidney; Kidney Diseases; Male; Metallothionein; Rats; Rats, Sprag | 2017 |
Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents; Brain Ischemia; Cyclooxygenase 2; Disease Models, | 2017 |
NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.
Topics: Acetophenones; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Capillary Permeability; Chem | 2009 |
Salvage of nonischemic control lung from injury by unilateral ischemic lung with apocynin, a nicotinamide adenine dinucleotide phosphate (NADPH) oxidase inhibitor, in isolated perfused rat lung.
Topics: Acetophenones; ADAM Proteins; ADAM17 Protein; Animals; Bronchoalveolar Lavage Fluid; Cell Membrane P | 2008 |
CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia.
Topics: Acetophenones; Animals; Brain; Brain Ischemia; Casein Kinase II; Cytoprotection; Disease Models, Ani | 2009 |
Increased ANG II sensitivity following recovery from acute kidney injury: role of oxidant stress in skeletal muscle resistance arteries.
Topics: Acetophenones; Acute Kidney Injury; Animals; Antioxidants; Arteries; Cyclic N-Oxides; Hydrogen Perox | 2010 |
Alcohol-induced exacerbation of ischemic brain injury: role of NAD(P)H oxidase.
Topics: Acetophenones; Animals; Blotting, Western; Brain Ischemia; Central Nervous System Depressants; Ethan | 2010 |
Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cytokines; Enzyme I | 2010 |
Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats.
Topics: Acetophenones; Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Cytochromes c; Disease Models, | 2011 |
Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.
Topics: Acetophenones; Animals; Bradykinin; Bradykinin Receptor Antagonists; Brain; Brain Ischemia; Capillar | 2011 |
NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion.
Topics: Acetophenones; Animals; Enzyme Inhibitors; Ischemic Attack, Transient; Male; Membrane Glycoproteins; | 2011 |
Interrupted reperfusion reduces the activation of NADPH oxidase after cerebral I/R injury.
Topics: Acetophenones; Animals; Down-Regulation; Enzyme Activation; Free Radicals; Male; Maze Learning; Memb | 2011 |
Blockade of NADPH oxidase restores vasoreparative function in diabetic CD34+ cells.
Topics: Acetophenones; Adult; Animals; Antigens, CD34; Benzodioxoles; Chemokine CXCL12; Cyclic GMP; Diabetic | 2011 |
Apocynin attenuates ischemia-reperfusion lung injury in an isolated and perfused rat lung model.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Disease Models, | 2011 |
Apocynin may limit total cell death following cerebral ischemia and reperfusion by enhancing apoptosis.
Topics: Acetophenones; Animals; Antioxidants; Apoptosis; Brain Ischemia; DNA Fragmentation; Dose-Response Re | 2011 |
Co-administration of apocynin with lipoic acid enhances neuroprotection in a rat model of ischemia/reperfusion.
Topics: Acetophenones; Animals; Brain; Brain Ischemia; Drug Combinations; Humans; Male; Neuroprotective Agen | 2012 |
UPEI-100, a conjugate of lipoic acid and apocynin, mediates neuroprotection in a rat model of ischemia/reperfusion.
Topics: Acetophenones; Animals; Biomarkers; Disease Models, Animal; Glutathione Disulfide; Infarction, Middl | 2012 |
Persistent oxidative stress following renal ischemia-reperfusion injury increases ANG II hemodynamic and fibrotic activity.
Topics: Acetophenones; Acute Kidney Injury; Angiotensin II; Animals; Blood Pressure; Creatinine; Disease Pro | 2012 |
Bone marrow derived cells and reactive oxygen species in hypertrophy of contralateral kidney of transient unilateral renal ischemia-induced mouse.
Topics: Acetophenones; Animals; Biomimetic Materials; Bone Marrow Cells; Cell Movement; Enzyme Inhibitors; G | 2012 |
The protective effects of apocynin on kidney damage caused by renal ischemia/reperfusion.
Topics: Acetophenones; Animals; Enzyme Inhibitors; Female; Kidney; Kidney Diseases; Rats; Rats, Wistar; Repe | 2013 |
Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus.
Topics: Acetophenones; Aldehydes; Animals; Antioxidants; Biomarkers; Brain Ischemia; Cell Death; Cerebral In | 2006 |
Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Recept | 2007 |
Rho-kinase as a novel gene therapeutic target in treatment of cold ischemia/reperfusion-induced acute lethal liver injury: effect on hepatocellular NADPH oxidase system.
Topics: Acetophenones; Acute Disease; Adenoviridae; Animals; Cold Temperature; Enzyme Inhibitors; Gene Expre | 2007 |
Protective effects of apocynin and allopurinol on ischemia/reperfusion-induced liver injury in mice.
Topics: Acetophenones; Allopurinol; Animals; Apoptosis; Enzyme Inhibitors; Glutathione; Liver; Malondialdehy | 2008 |
Ischemia-reperfusion lung injury is prevented by apocynin, a novel inhibitor of leukocyte NADPH oxidase.
Topics: Acetophenones; Animals; Enzyme Inhibitors; Lung; NADPH Oxidases; Neutrophils; Reperfusion Injury; Sh | 1999 |
Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury.
Topics: Acetophenones; Antioxidants; Enzyme Inhibitors; Humans; In Vitro Techniques; Indicators and Reagents | 2000 |